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Chinese Scientists Discover Structural Basis of Pre-mRNA Splicing

hackingbear writes: On August 21st, the research team led by Prof. Yigong Shi from School of Life Sciences, Tsinghua University in China published two side-by-side research articles in Science, reporting the long-sought-after structure of a yeast spliceosome at 3.6 angstrom resolution determined by single particle cryo-electron microscopy (cryo-EM), and the molecular mechanism of pre-messenger RNA splicing. Until now, decades of genetic and biochemical experiments have identified almost all proteins in spliceosome and uncovered some functions. Yet, the structure remained a mystery for a long time. The works, primarily performed by Dr. Chuangye Yan, and Ph.D students Jing Hang and Ruixue Wan under Prof. Yigong Shi's supervision, settled this Holy Grail question and established the structural basis for the related area. This work was supported by funds from the Ministry of Science and Technology and the National Natural Science Foundation of China.

2 of 48 comments (clear)

  1. Re: Remember when America had science? by Tablizer · · Score: 1, Flamebait

    At least we don't cover up our history like they do.

    Instead, we outsource Fox News and Rush L. to rewrite it. Those with money/power always find a way to tilt history.

  2. Now let's wait and see by Chas · · Score: 0, Flamebait

    Whether or not this is a genuine discovery, or yet another Chinese Hoax.

    --


    Chas - The one, the only.
    THANK GOD!!!