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Chinese Scientists Discover Structural Basis of Pre-mRNA Splicing

hackingbear writes: On August 21st, the research team led by Prof. Yigong Shi from School of Life Sciences, Tsinghua University in China published two side-by-side research articles in Science, reporting the long-sought-after structure of a yeast spliceosome at 3.6 angstrom resolution determined by single particle cryo-electron microscopy (cryo-EM), and the molecular mechanism of pre-messenger RNA splicing. Until now, decades of genetic and biochemical experiments have identified almost all proteins in spliceosome and uncovered some functions. Yet, the structure remained a mystery for a long time. The works, primarily performed by Dr. Chuangye Yan, and Ph.D students Jing Hang and Ruixue Wan under Prof. Yigong Shi's supervision, settled this Holy Grail question and established the structural basis for the related area. This work was supported by funds from the Ministry of Science and Technology and the National Natural Science Foundation of China.

5 of 48 comments (clear)

  1. Remember when America had science? by Anonymous Coward · · Score: 3, Insightful

    Those were good years.

  2. Can one do science without racism ? by Taco+Cowboy · · Score: 1, Insightful

    Is it so hard to do science without having to mixing in all the racist remarks?

    --
    Muchas Gracias, Señor Edward Snowden !
    1. Re:Can one do science without racism ? by Tablizer · · Score: 3, Insightful

      If it were American scientists and some Chinese made hamburger jokes, would it be "racist"? I don't know what the exact algorithm/formula is for determining "racism".

    2. Re:Can one do science without racism ? by Anonymous Coward · · Score: 0, Insightful

      > If it were American scientists and some Chinese made hamburger jokes, would it be "racist"?

      Of course not! It would be hilarious and fair, especially if there were hateful references to obesity!

      --SJW

    3. Re:Can one do science without racism ? by Applehu+Akbar · · Score: 1, Insightful

      If you read a food joke as a racist comment, then you're a SJW dumbass. Can you cite a genetic connection between ethnicity and cuisine?