Slashdot Mirror
Gene Drive Turns Mosquitoes Into Malaria Fighters (sciencemag.org)
sciencehabit writes: The war against malaria has a new ally: a controversial technology for spreading genes throughout a population of animals. Researchers report today that they have harnessed a so-called gene drive to efficiently endow mosquitoes with genes that should make them immune to the malaria parasite—and unable to spread it. On its own, gene drive won't get rid of malaria, but if successfully applied in the wild the method could help wipe out the disease, at least in some corners of the world. The approach "can bring us to zero [cases]," says Nora Besansky, a geneticist at the University of Notre Dame in South Bend, Indiana, who specializes in malaria-carrying mosquitoes. "The mosquitoes do their own work [and] reach places we can't afford to go or get to."
I got dibs on the movie rights.
Sheesh, evil *and* a jerk. -- Jade
Given how little we understand about the complexity of existing gene interactions and how they actually work, this whole concept seems a tad risky and unpredictable.
if it were in the hands of a caring, mature humanity. In the hands of a greedy pharma industry not so much...
The newest thing in Slashdot posts: don't even include an article. Nobody reads them anyway, so why bother? More professionalism from Dice.com staff.
Shutting down free speech with violence isn't fighting fascism. It IS fascism!
is to get rid of the mosquitoes directly by using selfish gene elements like segregation distorters. But imagine the "what could possibly go wrong" comments if you tried to even suggest this.
People tried to eradicate mosquitoes decades ago. Fish population suffered. We never know how things we hate are connected to the things we need. That's why it pays to consider long-term consequences before doing anything drastic.
There are risks in everything, but it is a safe bet you would change your tune if it was your child facing malaria.
And did you exchange a walk on part in the war for a lead role in a cage? - Pink Floyd.
There are risks in everything, but it is a safe bet you would change your tune if it was your child facing malaria.
Yes, but does desperation lead to good decision making? Desperation is what faith healers rely upon. Desperation is what the traditional healer that inadvertently helped spread ebola relied upon.
They already tried this in a number of areas - by introducing large numbers of Asian Tiger Mosquitoes. The males will mate with the Anopheles Mosquitoes that carry Malaria, but no offspring will be produced because the species are not compatible. Since female Mosquitoes only mate once, this renders them childless. It works quite well against Malaria, but the downside is that Asian Tiger Mosquitoes carry Dengue and other diseases that are only marginally less severe than Malaria.
People tried to eradicate mosquitoes decades ago. Fish population suffered.
Can you provide a citation for this? I can't find one. It's well-known that mosquitoes are nothing's favorite food, except perhaps species we only care about because they suppress mosquitoes like the mosquitofish which may have actually exacerbated the mosquito problem in Oz by outcompeting native mosquito-controlling fish.
So, what kind of fish are you talking about? And where is your citation?
"You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
"Gene drive" apparently means that these genes are passed on to almost all offspring instead of just 50% of them. Which would allow the genes to spread pretty much exponentially, if they can get it to work. Currently it seems to work really well when started in male mosquitoes, but not so well when started in females, so there's still some work to do.
And richer populations have fewer kids. If you're not living in an economically depressed malarial hellhole, you can afford birth control and set up a good economy.
Believe it or not, public health and improving people's economic status decreases birth rates.
Personally, I'd rather see worldwide populations limited by birth control and the naturally reduced birthrate that seems to ensue from better economic conditions than populations limited by war, famine, and pestilence.
--PeterM