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Gene Drive Turns Mosquitoes Into Malaria Fighters (sciencemag.org)
sciencehabit writes: The war against malaria has a new ally: a controversial technology for spreading genes throughout a population of animals. Researchers report today that they have harnessed a so-called gene drive to efficiently endow mosquitoes with genes that should make them immune to the malaria parasite—and unable to spread it. On its own, gene drive won't get rid of malaria, but if successfully applied in the wild the method could help wipe out the disease, at least in some corners of the world. The approach "can bring us to zero [cases]," says Nora Besansky, a geneticist at the University of Notre Dame in South Bend, Indiana, who specializes in malaria-carrying mosquitoes. "The mosquitoes do their own work [and] reach places we can't afford to go or get to."
I got dibs on the movie rights.
Sheesh, evil *and* a jerk. -- Jade
Given how little we understand about the complexity of existing gene interactions and how they actually work, this whole concept seems a tad risky and unpredictable.
if it were in the hands of a caring, mature humanity. In the hands of a greedy pharma industry not so much...
The newest thing in Slashdot posts: don't even include an article. Nobody reads them anyway, so why bother? More professionalism from Dice.com staff.
Shutting down free speech with violence isn't fighting fascism. It IS fascism!
is to get rid of the mosquitoes directly by using selfish gene elements like segregation distorters. But imagine the "what could possibly go wrong" comments if you tried to even suggest this.
There are risks in everything, but it is a safe bet you would change your tune if it was your child facing malaria.
And did you exchange a walk on part in the war for a lead role in a cage? - Pink Floyd.
There are risks in everything, but it is a safe bet you would change your tune if it was your child facing malaria.
Yes, but does desperation lead to good decision making? Desperation is what faith healers rely upon. Desperation is what the traditional healer that inadvertently helped spread ebola relied upon.
"Gene drive" apparently means that these genes are passed on to almost all offspring instead of just 50% of them. Which would allow the genes to spread pretty much exponentially, if they can get it to work. Currently it seems to work really well when started in male mosquitoes, but not so well when started in females, so there's still some work to do.
Malaria kills approx. 672k people/year worldwide (WHO: http://www.who.int/gho/malaria...).
Malaria cases per year, also very high in human cost, are much higher in number: 207M. AIDS has about 2x the death rate per year.
Maybe try this out on an island population of anopheles mosquitoes?
--PeterM
Mosquito bites are irritating, but as long as they don't spread disease they are endurable. Till the malaria pathogen mutates to find a new vector it would work.
sed -e 's/Chuck Norris/Rajnikant/g' joke > fact
And richer populations have fewer kids. If you're not living in an economically depressed malarial hellhole, you can afford birth control and set up a good economy.
Believe it or not, public health and improving people's economic status decreases birth rates.
Personally, I'd rather see worldwide populations limited by birth control and the naturally reduced birthrate that seems to ensue from better economic conditions than populations limited by war, famine, and pestilence.
--PeterM
It'd be much harder to do with antibiotics. The mosquitoes don't suffer a selective pressure from the gene drive - it doesn't hurt their chances of reproducing. Getting rid of antibiotic resistance in bacteria, of course, does.
Examine even your most deeply held beliefs. Nobody is always right.