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Gene Drive Turns Mosquitoes Into Malaria Fighters (sciencemag.org)

sciencehabit writes: The war against malaria has a new ally: a controversial technology for spreading genes throughout a population of animals. Researchers report today that they have harnessed a so-called gene drive to efficiently endow mosquitoes with genes that should make them immune to the malaria parasite—and unable to spread it. On its own, gene drive won't get rid of malaria, but if successfully applied in the wild the method could help wipe out the disease, at least in some corners of the world. The approach "can bring us to zero [cases]," says Nora Besansky, a geneticist at the University of Notre Dame in South Bend, Indiana, who specializes in malaria-carrying mosquitoes. "The mosquitoes do their own work [and] reach places we can't afford to go or get to."

6 of 69 comments (clear)

  1. What could possibly go wrong. by Black+Parrot · · Score: 3, Insightful

    I got dibs on the movie rights.

    --
    Sheesh, evil *and* a jerk. -- Jade
  2. Re:The new Dice.com RTFA by Anonymous Coward · · Score: 3, Informative

    http://news.sciencemag.org/health/2015/11/gene-drive-turns-insects-malaria-fighters
    It's next to the title?

  3. Re:Another possibility by whitesea · · Score: 5, Informative

    is to get rid of the mosquitoes directly by using selfish gene elements like segregation distorters. But imagine the "what could possibly go wrong" comments if you tried to even suggest this.

    People tried to eradicate mosquitoes decades ago. Fish population suffered. We never know how things we hate are connected to the things we need. That's why it pays to consider long-term consequences before doing anything drastic.

  4. Re:So how will cattle DNA react? by TapeCutter · · Score: 4, Insightful

    There are risks in everything, but it is a safe bet you would change your tune if it was your child facing malaria.

    --
    And did you exchange a walk on part in the war for a lead role in a cage? - Pink Floyd.
  5. Re:Two minds about this by michelcolman · · Score: 3, Interesting

    "Gene drive" apparently means that these genes are passed on to almost all offspring instead of just 50% of them. Which would allow the genes to spread pretty much exponentially, if they can get it to work. Currently it seems to work really well when started in male mosquitoes, but not so well when started in females, so there's still some work to do.

  6. Healthier populations have fewer kids by PeterM+from+Berkeley · · Score: 4, Insightful

    And richer populations have fewer kids. If you're not living in an economically depressed malarial hellhole, you can afford birth control and set up a good economy.

    Believe it or not, public health and improving people's economic status decreases birth rates.

    Personally, I'd rather see worldwide populations limited by birth control and the naturally reduced birthrate that seems to ensue from better economic conditions than populations limited by war, famine, and pestilence.

    --PeterM