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Antibiotic-Resistant E Coli Reaches The US For The First Time (reuters.com)

New submitter maharvey writes: A woman in Pennsylvania has contracted a strain of E Coli that is unaffected by all known legal antibiotics, including the antibiotics of last resort. We have had bacteria that were resistant, but this is the first bacteria that is completely immune. Such bacteria were known in China, but since the woman has not traveled recently it means she contracted it in the wild in the USA. This is a major step toward the terrifying post-antibiotic world.

38 of 203 comments (clear)

  1. the chickens. by Gravis+Zero · · Score: 3, Insightful

    they've come home to roost.

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  2. Re:Does vodka help? by Anonymous Coward · · Score: 5, Funny

    I regularly have my Russian women consume vodka before placing their proverbial lips on my appendage. That is, after I place my tinfoil hat on and cross my fingers. So far so good. My anecdotal evidence supports your inquiry AND you read it here on the internet so it must be true.

  3. Antibiotic abuse and biodiversity by Anonymous Coward · · Score: 5, Insightful

    Biodiversity is a good thing, but we're destroying it. We need to allow nature to create new antibiotics and use those as needed.

    Also, there are some fucking absurd abuses of antibiotics. Doctors are way too quick to wrote prescriptions when they aren't necessary. We need to stop prescribing antibiotics when they aren't necessary for infections that will be stopped by the body's immune system or as preventive measures.

    Furthermore, we shouldn't be wasting antibiotics on animals, especially for cattle. I'm sorry that one of the animals in your herd is sick. There's no fucking reason to put antibiotics in the feed of all of your cattle. That's fucking ridiculous. Don't use antibiotics on cattle.

    This is a fucking big deal. People who misuse antibiotics should lose their license to practice medicine. I'd also support prison time for it.

    1. Re:Antibiotic abuse and biodiversity by golodh · · Score: 5, Interesting
      Apart from your gratuitous use of the f-word, I agree.

      Perhaps this woman's imminent death can serve as a rallying point to ban the (grossly irresponsible) use of antibiotics in foodstock fodder.

      Expect the foodstock industry to fight any such suggestion tooth and nail of course. Such a ban will cost them money since foodstock put on weight more slowly when not dosed with low levels of antibiotics, and any scare stories about antibiotics-resistant bacteria are "so many radical treehuggers' fantasies" of course.

      "Huh ... it's already happened you say? I thought we had another five years at least. Hmm ... denounce the linkage a speculation based on evolution theory, increase the lobbyist budget, and see if we can't get a deal with a nice understanding conservative presidential candidate."

      Why oh why do we need to actually see an antibiotics-resistant bacteria infect somebody before we'll acknowledge the blindingly obvious about to happen?

    2. Re:Antibiotic abuse and biodiversity by ilsaloving · · Score: 2

      The only problem is that, like climate change, it's already too late. We should have taken control of antibiotics use *before* antibiotic-immune bacteria evolved. Now it's too late.

      But as usual, people are too greedy and short sighted to care about minor details like destroying the single biggest and most important defence modern medicine has to help people.

    3. Re:Antibiotic abuse and biodiversity by yes-but-no · · Score: 3, Insightful

      Why oh why do we need to actually see an antibiotics-resistant bacteria infect somebody before we'll acknowledge the blindingly obvious about to happen?

      Because, Sir, we as a species are dumb.

    4. Re:Antibiotic abuse and biodiversity by silentcoder · · Score: 2, Insightful

      Well... we lack anything at all to stop it from doing so.

      How soon people forget... less than a hundred years ago the vast majority of bacterial infections were fatal. Penicillin has saved more lives than we can count, probably at least as many as pasteurization (which we've had for 2 centuries longer). Destroying the efficacy of our most powerful life-saving weapon through overuse remains one of the most monumentally stupid things humanity could ever do and we seem hellbent on doing it.
      This is the bacterial equivalent of anti-vaxxers and both are risking not just their own lives but millions, perhaps billions, of others. There have been multiple plagues in history that wiped out 25% or more of the human population, and those were all constrained by geography - a constraint that does not exist today - oh and some of the worst of them were bacterial. The most famous - the black death - was caused by bubonic plague, a bacterial infection. Imagine if a bacterium or virus with the virulence of bubonic plague happened today... we could easily see 75% or more of humanity dead just from direct infection. City streets lined with corpses - the cleanup services long ago overrun so every body lies there for weeks stinking and spreading the disease further. Quarantines become impossible to enforce as there are just not enough healthy people to enforce them. Complete economic collapse as every industry grinds to a standstill. All of which cause more deaths and violence. Some economists have calculated that Africa's negative GDP can be ENTIRELY accounted for by Malaria and, if that was eradicated, it would be a rich continent. And compared to something like plague, malaria is a lightweight since it can't spread anywhere that doesn't have a suitable climate for the one mosquito that can spread it.

      Of course those who profit from some blatantly idiotic things as giving antibiotics to factory farmed animals to boost growth would call this alarmist... and conveniently forget that this has happened before, many times. It is not alarmist to say that if we destroy the thing that made it stop happening, that it would happen again.

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    5. Re:Antibiotic abuse and biodiversity by silentcoder · · Score: 2

      Yeah bubonic plague was just a story right. Immune systems are actually pretty limited things without drugs that help them - and historically, most people did NOT survive most infections. There is no evolutionary drive to evolve a GOOD immune system - just good enough for SOME to survive.

      Oh and about 99% of natural immune system consists of one organ: the skin. Once an infection gets past that barrier it's odds of killing are pretty high. Even the flu can easily have high fatality rates if just a few conditions converge. Somewhere between 3 and 5 percent of the entire human population was killed by a single flu outbreak a mere 98 years ago. Aggravated by the fact that a world war had concluded just a few months earlier.

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    6. Re:Antibiotic abuse and biodiversity by silentcoder · · Score: 2

      Frankly, it makes a helluva lot more sense to throw these people in prison (for risking the wellbeing of the entire human race) than to throw kids in there for smoking some weed and risking exactly no harm to anybody at all.

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    7. Re:Antibiotic abuse and biodiversity by Evtim · · Score: 2

      And for the bacterial infection go phage! Oh, but you can't patent a naturally occurring cure. We can't have that - saving lives without making PROFIT....are you Marxist or something ;)

    8. Re:Antibiotic abuse and biodiversity by PCM2 · · Score: 4, Informative

      Well... we lack anything at all to stop it from doing so.

      We may lack anything. But she has something ... it's called an immune system.

      Note, also, that the Reuters story has been corrected. They analyzed the woman's bacteria and noticed it would be resistant to colistin, a "last-resort antibiotic." It's not resistant to all the other ones, too -- unlike what the first version of the story said. It's just that we know bacteria can be resistant to all the other ones, and it wouldn't be so hard for this strain to pick up those other genes, resulting in an unstoppable bacteria. This is not that unstoppable bacteria; but it's proven once again that it is theoretically possible for one to exist.

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  4. Re:Does vodka help? by Anonymous Coward · · Score: 2, Funny

    Topical alcohol is an excellent disinfectant, however for internal infections alcohol tends to kill the host before the bugs so not such a good idea.

  5. Re:Does vodka help?RTFA by zlives · · Score: 2

    protect themselves from the superbug and from other bacteria resistant to antibiotics by thoroughly washing their hands, washing fruits and vegetables thoroughly and preparing foods appropriately.

  6. Perhaps not use antibiotics on animals by NotInHere · · Score: 5, Insightful

    what about not using antibiotics on living animals? They serve as a feeding ground for antibiotics. The price would be that you have to pay more for products that include flesh, because you would have to isolate the animals better, in order to stop spreading illnesses.

    1. Re:Perhaps not use antibiotics on animals by NotInHere · · Score: 2

      I would draw it between humans and animals. Maybe pets should get an exception, but even there the list of allowed antibiotics should be highly limited.

    2. Re:Perhaps not use antibiotics on animals by gumbi+west · · Score: 2

      As a living animal who has been helped by antibiotics, I object.

  7. Nice job humanity! by slacka · · Score: 4, Insightful

    Total Failure of Government and Society and not a good sign for the future of the human race. I personally have been well aware of the risks of Antibiotic-Resistant for over 20 years. This was the text book example of natural selection in my High School Biology class.

    Instead of listening to the scientists and public health officals on the risks, we have let the greed and money in big ag run make our laws. We let them dump antibiotics in our livestock food in so we could have cheap meat and now the chickens are coming home to roost.

    Welcome back to the pre-antibiotic era where a cut can be deadly and hospitals can kill you. Nice job humanity!

    1. Re:Nice job humanity! by Anonymous Coward · · Score: 2, Insightful

      Nice job humanity!

      The human race has never had a good long game. Immediate comfort is irresistible to all animals.

    2. Re:Nice job humanity! by Anonymous Coward · · Score: 2, Informative

      One minute you blame government, the next you say we should listen to "public health officials." I think you contradict yourself.

      Not a contraction at all. The government as a whole can fail the people, while individuals within the government can warn of the impending threat.

      Watch Frontline's "The problem with antibiotics", there a member of the CDC, a "public official", warns about feeding antibiotics to livestock, however the CDC cannot regulate animal food, that's the FDA's role. But the FDA's hands are tied by Senators who have been corrupted by big ag's money. Hence, our government failed us because "corporations are people".

    3. Re:Nice job humanity! by silentcoder · · Score: 2

      While I agree with your sentiment, your example is flawed. Chernobyl was a private corporation - they are an example more like Enron than like government. In fact that company still exists, and is still in business. My own government seems hellbent to sign a major nuclear procurement deal with them... because of COURSE we'll buy our nuclear reactors from the only company to ever blow one the fuck up.

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  8. "Such bacteria were known in China..." by JoeyRox · · Score: 3, Funny

    More proof of our trade imbalance with China.

  9. Re:Try the original antibiotic by ttucker · · Score: 4, Insightful

    Until you turn blue.

  10. Re:Try the original antibiotic by swell · · Score: 2, Interesting

    Sorry you are unable to follow the Google suggestion. When you learn to read before you rant you will eventually discover that the FUD about silver safety is a scam. You need to consume gallons over a long period of time to experience a change of skin color, and even then it doesn't seem to have health consequences.

    When you are selling an expensive patented antibiotic and competing against less expensive OTC silver, will you spread the joy that silver is more effective? Or will you look for any way to eliminate the competition? Use your head when you read various opinions. Or join the marketing staff at Monsanto where they need shills like you.

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  11. Re:Blame the farmers .. yeah ! by Anonymous Coward · · Score: 3, Informative

    This is only a problem for factory farms. Regular farms don't need to rely on antibiotics to keep animals healthy.

    We should ban factory farming techniques.

    It will drive the price of meat up significantly. That's fine; a whole generation of first-worlders can learn just how protein-rich a plant-based diet can be (before you object, be aware that the shaolin monks (the most powerful athletes in the world) live on a strictly vegan diet from the day they start training (at around 5 years of age). If THEY can do it, so can you!)

  12. Crop Rotation by ThatsNotPudding · · Score: 4, Interesting

    This is a stupid question, but I've always wondered why old (very old, unused for decades) antibacterials can't be resurrected with a restored effectiveness. I liken it to the idea of rotating crops so the field soils aren't totally stripped of nutrients by planting the same crop year after year.

    I mean: what does in benefit rather simple organisms to continue to pass along resistance to a spectrum of anti-biotic that their ancestors hadn't been exposed to in decades (and that's how many bacterial generations)? Isn't there a 'carrying capacity' or 'memory limit' to what can be added to their code that has to be slowly deprecated / de-prioritized just for physical space constraints? Asserting they have the Borg-like ability to perfectly add to their defenses without end, sounds a bit too apocalyptic to me.

    1. Re:Crop Rotation by Zontar_Thing_From_Ve · · Score: 4, Interesting

      This is a stupid question, but I've always wondered why old (very old, unused for decades) antibacterials can't be resurrected with a restored effectiveness. I liken it to the idea of rotating crops so the field soils aren't totally stripped of nutrients by planting the same crop year after year.

      It's not a stupid question at all. Frankly, people should be asking this question in case nobody thought of it. The problem is that this has actually been tried and in a lot of cases it hasn't helped. Some of the older drugs stopped being used because they were toxic or had some very undesirable possible side effects and they were replaced with drugs that were safer to the patient to use. It turns out that once bacteria start getting highly resistant that they are basically resistant to almost everything including the older drugs. We desperately need drug manufacturers to get interested in new lines of antibiotics, but due to research cost there hasn't been a lot of interest in developing new ones. And as others have pointed out given how the government seems completely and utterly disinterested in the USA (and other countries) in stopping people from giving antibiotics to livestock, we've created this mess ourselves and seem oddly uninterested in fixing it.

  13. Not humanity. Capitalism. by Uberbah · · Score: 2

    It's not like there was a mass social movement demanding that cows be inundated with antibiotics because they're knee-deep in their own shit on a factory farm. Like climate change, asbestos or the tobacco industry, this is about profit for a handful of people.

  14. Re:Blame the farmers .. yeah ! by Opportunist · · Score: 3, Informative

    Personal responsibility (or rather "don't give a shit about anyone but yourself") yes. But god forbid corporations would be responsible for anything they do! That could endanger jobs! Not to mention profits.

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  15. Re:Does vodka help? by PolygamousRanchKid+ · · Score: 2

    I regularly have my Russian women consume vodka before placing their proverbial lips on my appendage . . . you read it here on the internet so it must be true.

    Read?

    GIFs or JPGs, or it never happened.

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  16. Re:Try the original antibiotic by Opportunist · · Score: 2

    Wow, the medical woo preachers have reached /. I thought I wouldn't see the day.

    OK, if you want to join the blue man group and don't mind your kidneys to shut down eventually, go for it. Wash it down with a big glass of chlorine bleach that you idiots love so much as well, just please don't use it on your kids.

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  17. Re:Blame the farmers .. yeah ! by dow · · Score: 5, Informative

    Real life farmer here. Maybe is the USA cows in pastures are a lie, but in the UK ours spend the summer out in the fields. It's cheaper to keep them in a pasture than in a barn. Also, we don't feed our cows antibiotics. Again, that's something they might do in the US, but in Europe antibiotics in cattle feeds have been banned for quite some time. We have some factory farms in the UK also, but nothing the size of many US herds. One farmer wanted to build an eight thousand head farm, but it made national news and there was massive public resistance. They do not want that sort of farm in the UK.

    If you want to blame farmers for using such practises, blame yourself for looking for the cheapest food you can get. Supermarkets compete on prices. You wanted cheap food, you got cheap food. Now, you realise the price of that cheap food. The farmers were just giving people what they wanted, the cheapest food they could produce. Did you ever pick up an item at the supermarket and think that it was too cheap? When it comes to many quality foods, people should really stop asking themselves "Why is it so expensive?" and ask "Why is the other stuff so cheap?"

  18. Silver poisonning by aepervius · · Score: 2

    https://en.wikipedia.org/wiki/...
    Not life threatening but the quantity of silver required to effectivelky treat such bacterial infection may lead easily to agyria, localized or generalized. On the other hand we may get better avatar porn, so there is a, hehe , silver lining. (and now I'll slap myself silly for the easy joke).

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  19. Re:Try the original antibiotic by sackvillian · · Score: 2

    When you are selling an expensive patented antibiotic and competing against less expensive OTC silver, will you spread the joy that silver is more effective?

    I'm not sure where you live, but here in Ontario we have a law that all prescriptions must be automatically replaced with generic versions unless otherwise specified by the physician (very rarely). And guess what? There have not been many new antibiotics discovered in the past 15 years, so the vaaaast majority prescribed are generic. We further make use of all sorts of topical antibacterial solutions containing iodine and hydrogen peroxide, for example.

    In other words, if there was any validity at all to what you were saying, physicians would jump at the chance to prescribe silver.

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  20. Re:An abundance of caution by coofercat · · Score: 2

    Had that abundance of caution extended to not giving humans and livestock antibiotics that they didn't need, then we'd probably have another 20 years to develop some new antibiotics.

  21. Re:Blame the farmers .. yeah ! by Khashishi · · Score: 2

    Everywhere you look, you see tragedy of the commons. But the libertarians continue to blame regulation.

  22. Re:Blame the farmers .. yeah ! by minstrelmike · · Score: 2

    Farms don't overuse antibiotics to keep their animals healthy; they overuse them to make them gain weight faster.

  23. Re:Blame the farmers .. yeah ! by Khashishi · · Score: 2

    That's stupid. Whose private property will the air fall under if we abolish the government? OK, suppose it's yours. How are you even remotely capable of protecting your private property from exploitation by others without government regulation?

    Private property exists because regulations exist to protect private property. Regulation creates things like mineral rights and spectrum rights and land deeds.

  24. Re: Blame the farmers .. yeah ! by Opportunist · · Score: 2

    "War on Christianity"? Melodrama much?

    Only in America would giving someone rights be seen as taking away someone else's rights.

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