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Alcohol Can Cause Irreversible Genetic Damage To Stem Cells, Says Study (theguardian.com)
A new study, published on Wednesday, states that drinking alcohol produces a harmful chemical in the body which can lead to permanent genetic damage in the DNA of stem cells, increasing the risk of cancer developing. From a report: The research, using genetically modified mice, provides the most compelling evidence to date that alcohol causes cancer by scrambling the DNA in cells, eventually leading to deadly mutations. During the past decade, there has been mounting evidence of the link between drinking and the risk of certain cancers. "How exactly alcohol causes damage to us is controversial," said Prof Ketan Patel, who led the work at the MRC Laboratory of Molecular Biology in Cambridge. "This paper provides very strong evidence that an alcohol metabolite causes DNA damage [including] to the all-important stem cells that go on to make tissues." The study builds on previous work that had pinpointed a breakdown product of alcohol, called acetaldehyde, as a toxin that can damage the DNA within cells. However, these earlier studies had relied on extremely high concentrations of acetaldehyde and used cells in a dish rather than tracking its effects within the body.
Hi,
I'm in my mid thirties, rather accomplished, with a very good job (tech) that I like, family with 2 kids etc. I drink way too much however and I fear I'm already borderline alcoholic. I've recently found this 'high functioning alcoholism' term and realized this is me. Which scares me a lot. I do know people that drink a lot in my family (I'm from eastern Europe...) and until recently I've never considered myself similar to them. For the record, I'm drinking on average 5 evenings per week, between half and a full bottle of wine (which is not that much, certainly I got used to it, so it doesn't put me in the drunk mode neither).
I keep an 'inner scorecard' which means I evaluate myself against what I used to be, and what I think I can accomplish (did I perform / accomplish something up to my potential, or did I just did a half-ass effort). Funnily enough, I always somehow discarded alcohol as a factor, justifying it (to myself) that it's not that influencing. Which is of course false. I should add that I work in the evenings very often (I love what I do btw) and most of those time, I drink too when working.
What made me realize this problem much more efficiently was running. I started quite recently and did some tests - how I perform, with the same training scheme, with and without alcohol for a period of time. Numbers don't lie. I run much better and also feel better.
As to why I'm drinking when I'm working alone, I don't really know (other than I like the taste). Not necessarily to forget problems or something. With perspective, this amounts to huge chunks of time, which certainly impacts my work on side projects / business. Sometimes I think I drink because I'm scared to actually succeed with this side stuff, and somehow unconsciously I sabotage myself.
Are / were you in this situation ? If you managed to stop, I would appreciate the 'how'.
There's a pretty huge gap between
"Alcohol Can Cause Irreversible Genetic Damage To Stem Cells, Says Study"
and
"However, these earlier studies had relied on extremely high concentrations of acetaldehyde and used cells in a dish rather than tracking its effects within the body."
Thanks but we already knew that alcoholic have an higher risk of cancer : https://www.elementsbehavioral...
But I guess I should be thankful that, for once, the real signifiant fact is inside the summary...
Elok
Itâ(TM)s like this: what do you do to prevent an infection if you get cut? You put alcohol on it, and thst kills germs.
Whatâ(TM)s sickness but germs inside your body? You know what to do
Put me off drinking over the course of 10 years. My grandfather was an alcoholic. I could have drank like him.
Another thing is that I like to code and my brain cannot handle it on liquor.
Expecting family to help is a nonstarter. They are the cause of trouble, not the cure, at least for me.
Now that the alcohol is proven haram (harmful and unclean according to the goatfucker in chief), we are waiting for studies to "scientifically" prove that eating pig causes cancer and not wearing hijab causes cancer as well (and rape).
So forbidding alcohol, pig meat and not wearing hijabs is not to appease the bloody moslems, but because this is "scientifically proven" that they cause harm,
It's really nothing that the fucking globalists and their subservient liberal cuckers that won't spoil to push their stinky agenda ???
A "party foul" at the lab is unacceptable, JOHN! ;)
Anons need not reply. Questions end with a question mark.
They lack the natural resistance to cancer that humans have, because they don't really need it. So studies like this don't show anything really conclusive.
Now pass me that bottle!
This is from the same kind of "scientists" who claim things like evolution and global warming are real. Meanwhile for all their "evidence" they still can't explain how the eye evolved or why its so fucking COLD outside.
Wasn't Acetaldehyde shown to form in the saliva of Alcohol drinkers over a decade ago?
I expect to hear from the usual mixture of deniers and and 'I told you so' folks now. Oh how tedious...
So, let's wait until further studies are performed across the World and when they agree or disagree with this finding, we can make a decision then? A vain hope I know....
Stuart http://stuarthalliday.com/
both of my grandparents were very heavy drinkers and lived to be over 95.
Last night my wife and I helped an old lady up. She had literally fallen and couldn't get up. My nose soon detected that her problem wasn't that she was old, but that she was drunk as a skunk.
This morning we found out that this is normal for her and she's been a lifetime alcoholic. So you could argue that she won the alcoholics lottery. She's well over 80 and she got to spend here life drinking. Most of us would die of cancer or liver failure before we got to the retirement community.
I should use this sig to advertise my book ISBN-13 : 978-1501515132.
So moderate alcohol use (supposedly) helps prevent heart disease but also (supposedly) increases your odds of cancer.
On one hand, repairing or replacing hearts, possibly from cloned stem cells, is theoretically easier than curing cancer and repairing damaged stem cells.
On the other hand, a heart attack is a lot more likely to catch you by surprise before you realize you need to have your heart repaired or replaced. Also, your stem cells are going to get damaged sooner or later anyways, alcohol just speeds up the process. So sooner or later we'll have to figure out how to repair or replace stem cells anyways.
Of course that's all taking the long view. In the short(er) view, none of us are getting out of this alive. So drink up i guess?
This Space Intentionally Left Blank
You're drinking alone while you work probably because it helps numb your mental fatigue and/or your muscular pain from hunching over a computer.
Here's how to stop drinking: Every time you crave some alcohol, evaluate yourself for why you are craving it; if you notice that your neck/shoulders are killing you, or that you're actually kind of tired, then take a damn break! Do some exercises, or stretching, or take a nap, or get a snack. Eventually, you'll retrain the AI in your head to associate those alternatives (rather than alcohol) with an improvement in your sense of comfort.
Hey, drinking was once useful to you; it's not anymore. That's all there is to it; you are in control.
Which leads me to think getting cancer has a lot more to do with genetics than external factors.
I guess this explains APK then.That and fetal alcohol syndrome. Maybe his mom doing 5lbs of blow a day too. Dammit I forgot about his eating of paint chips also.
If someone offers you a beer, according to this research, they are trying to kill you.
I like to share my story with fellow techies.I was a heavy drinker. I started drinking when I was in 16 or 17, but never abused much until I was 40 or 41. Then I started drinking heavily , 1-2 bottles of Brandy or Whiskey a week and been and wine occasionally. I knew I had a problem, but I was't an alcoholic to anyone . I had a few minor accidents. Finally I started thinking about why I need to drink. The underlying problem was an unhappy relationship. That ended almost 2 years back after 16 years. I given up drinking and smoking almost the same time. This may not be popular here, but I turned into spiritual help and it worked wonders in my life. I don't have any temptations anymore. I am with smokers and go to bar with friends, but enjoy a pepsi or water with them. I don't take a moral position on who can drink responsibility, but I think there are people who shouldn't be drinking. And never user alcohol to resolve solve and actual problem like relationship or join pain.
I exercise regularly and eat right. My triglycerides is with in the range and sleep changed. At 45 I feel like 22. I lost a lot of friends when I stopped drinking, but they were probably not friends to begin with. I am in a new relationship and hopefully everything is behind me. I know some of the stories are very true . Good luck and never give up.
From TFS:
Those who turn red in the face after drinking (Asians often have a genetic issue that causes this, btw) should pay particular attention to this symptom; the reason for the red face is an acetaldehyde dehydrogenase deficiency, which results in an accumulation of acetaldehyde, which in turn has been associated with an increased risk of esophageal cancer.
cite
I've fallen off your lawn, and I can't get up.
Be careful. You can develop a drinking problem
At least if you're male, if nothing else kills you, prostate cancer most certainly will.
But if you're not male, it doesn't matter really - stick around long enough, and you cannot avoid your cells fucking up during reproduction.
No Magic Science Diet Woo is going to change that.
Tonight we drink, for tomorrow, or hopefully a few decades from now at least, we die.
There really isn't a good way to solve it yourself unless you are willing to change your *ENTIRE LIFESTYLE*.
That may sound a bit ominous and crazy, but it is true. Your friends will try and drag you back into drinking with them, you will find peer pressure difficult to withstand, and as you cut back on drinking, many of your friends will likely turn on you for not 'partying with them'.
While I haven't dealt with this personally, my parents have run into it with their 50-70 aged crowd of friends, and a cousin who has finally after three years started purging her social circle after multiple incidents with drunk friends at annual events have lead her to agree with my opinion on running dry social events. While she hasn't done it yet, she's been cutting back on the alcohol at her parties, and noting how many of her presents are booze related, indicating people didn't really know much about her outside of alcohol.
As we all know and as has been Proven by no less than the Great Dr. Johnny Fever, drinking makes your reflexes faster
When Fascism comes to America, it will call itself Anti-Fascism, and tell you to give up your guns.
Next week, who knows.
...I need a drink!!
Explains why practicing moslems are generally (exceptions exist) more terse and less open and happy than christians. It's quite obvious when you deal with Lebanese where both religions coexist.
Sugar: The Bitter Truth — 2009, 7.5 million views
The Hacking of the American Mind with Dr. Robert Lustig — 2017
John Yudkin: the man who tried to warn us about sugar — 2014
Many serious people now believe that excess fructose (which is metabolized in the liver through much the same pathway as ethanol) is the largest single causal component to the metabolic syndrome epidemic, which is itself one of the largest single causes of runaway healthcare costs in the United States.
Salt, Sugar, Fat: How the Food Giants Hooked Us by Michael Moss — 2013
How the Food Makers Captured Our Brains — 2009
Sugar is the tongs and the hammer.
As Lustig once said (from memory): given the choice between sugar and alcohol, I'll take alcohol, because you can only drink yourself under the table once a day.
dude you are whst you eat. and everybody who drinks are jerks. i smoke pot and love myself.
Actually, I think the title of this post explains it all - there's a few thousand miles of difference between "can cause" and "will cause."
An enigma, wrapped in a riddle, shrouded in bacon and cheese
First step for me was being genetically predisposed to gout. Then getting gout, then quitting meat as well as alcohol for a year and STILL getting gout. For the gout, uloric completely cured me, however i do have to take a pill once a day every day. I did not start drinking again, and now am at year three.
I still think about drinking lots, however what i do since medical marijuana is legal where i am, is take some phoenix tears whenever i have a craving. I completely lose the urge to drink and it does not return for a few days at least. I dont like smoking joints (lung butter, reduced lung performance, chronic coughs) however i also use a vapourizer on occasion.
Anyways thats my recommendation. Phoenix tears. If you have an addictive personality and or you just find life boring without drinking, you might try switching to thc and cbd. Its far less harmful, i get next to no headaches now, my weight is wayy down and i dont have to exercise as hard to keep it off. I am also far less moody, angry and more mellow.
I really dont think you drink that much though. I would drink 2.5 bottles of wine a day, but i much prefer a mikki of liquor every day and 2 beers. As you can imagine this got really expensive. Did home brewing as well to try and overcome the cost, but its true what they say that you can only drink 30 glasses of beer a day no matter how rich you are... and i would never really get drunk was the real kicker. if i drank fast (350ml liquor every hour), or had something that was 60%, then maybe. Most times i would just fall asleep, so in the end it was pointless to continue.
tldr: phoenix tears.buy at a dispensary near you!
This just in...
Almost anything can cause a genetic change to the bodies cells! Water, Sunlight, Foods, Air...
Every cell in the Human body has the chance of becoming a cancer cell...
Instead of articles about what causes it, I only want to hear/read about those that cure it. Everything can cause cancer, because cancer is you, go ask a fish.
Thanks for the laugh, that was a good joke.
Also, drinking alcohol kills some cells. But if you study natural selection, only the weakest gets killed. Hence, drinking alcohol just kills weak and slow cells and thereby leaving you with a very strong and healthy cells on your body every time you binge on alcohol.
The immediate questions that come to mind are how much alcohol, and how long?
I mean, is this a beer or one mixed drink, a shot or so, a day, or are we talking alcoholics who need alcohol all the time, or the binge drinkers, who are doing it most weekend?
I remember the Studies Proving The Killer Weed Causes Cancer. Um, yupper, they were using mice, and if you smoked that much, you'd be asleep 20 or more hours a day, and either smoking or eating the rest of your waking hours, *and* you'd need really, really potent weed.
I expect this to be the same. And are they also worried about elephants, who have been documented going out of their way to drink rotted, fermented fruits? Or monkeys doing the same? Or that maybe we've been drinking since we were proto-human?
Or maybe The Monolith started dispensing booze.....