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Two Twin Long-Tailed Macaque Monkeys Are the First Primates Cloned Using the Dolly Method (arstechnica.com)
An anonymous reader quotes a report from Ars Technica: The twin long-tailed macaque monkeys are the first primates cloned using the same method that created the world's most famous sheep in 1996 -- a method called somatic cell nuclear transfer, or SCNT. The twins' genetic blueprints were swiped from fetal cells of another monkey. Researchers then popped the DNA into egg cells that they had also cleared of their DNA-containing nuclei. With a dash of compounds that spur embryo development, the reprogrammed cells developed into healthy baby monkeys in surrogate mother monkeys. The two were born about seven weeks ago in China and are developing normally so far, researchers reported Wednesday in the journal Cell. Though the overall SCNT method is the same as what was used for Dolly, researchers struggled for years to tweak it to work in primates. The procedure is delicate and required a lot of optimization -- not to mention DNA-swaps.
The researchers behind the cute clones, led by Zhen Liu of the Chinese Academy of Sciences, first tried using DNA from adult monkey cells. They created 192 embryos this way, implanting 181 of them into 42 surrogates, leading to 22 pregnant monkeys. But this resulted in the live birth of only two monkeys, both of which died within hours. Next, the researchers tried using DNA from fetal tissue. They created 109 embryos, implanted 79 of them into 21 surrogates, leading to pregnancy in six of them. Two female monkeys, Zhong Zhong and Hua Hua, resulted. The researchers attribute their success to new cell-imaging methods, tweaking the right mix of reprogramming compounds, and lots of practice.
The researchers behind the cute clones, led by Zhen Liu of the Chinese Academy of Sciences, first tried using DNA from adult monkey cells. They created 192 embryos this way, implanting 181 of them into 42 surrogates, leading to 22 pregnant monkeys. But this resulted in the live birth of only two monkeys, both of which died within hours. Next, the researchers tried using DNA from fetal tissue. They created 109 embryos, implanted 79 of them into 21 surrogates, leading to pregnancy in six of them. Two female monkeys, Zhong Zhong and Hua Hua, resulted. The researchers attribute their success to new cell-imaging methods, tweaking the right mix of reprogramming compounds, and lots of practice.
Could we focus are efforts on something a little more tasty?
oooohhhh yeah
That ape is artificial AF, everyone sees it now whether they admit it or not.
I'm pretty excited about having hot swappable organs all ready for my old age stored in my lobotomized clone body.
Some drink at the fountain of knowledge. Others just gargle.
(throwing banana)
"Two Twin Long-Tailed Macaque Monkeys Are the First Primates Cloned Using the Dolly Method"
My first attempt to parse this resulted in me thinking there was some sort of monkey with two tails, and now I am sad that there is not.
... Monkeys Are the First Primates Cloned Using the Dolly Method
I initially read that as "Pirates Cloned".
Then I thought of the musical Hello Dolly, then imagined a musical version of Pirates of the Caribbean -- "Curse of the Lead Feet", then wondered if they could use cloned monkeys for that.
It must have been something you assimilated. . . .
China's scientists working hard to clone Mao so he can kill them all over again.
nt
Invest in organ farming... Because this signals the dawn of it. The SECOND people can be cloned, the organ farms will begin. Bodies without brains. Empty shells filled with replacement parts. EXACT replacement parts... No Rejection. No Lifetime of Anti-Rejection Drugs. The New world of 140-200 year old elitists, taking OLD money to all new heights. Sociopaths that can live two CENTURIES. Isn't this JUST what the world needed? INVEST NOW! SCREW BITCOIN! :-D
LOL!
So now there 's the possibility for rich narcissistic megalomaniac assholes to clone themselves? (Anyone come to mind?)
to the fabled 12-assed monkeys?
(Everyone has agreed to not post any serious comments about the story, right? Ok, good. No adults allowed!)
As someone who plays Dwarf Fortress, I just want to be the first to say: Fuck rhesus macaques! We should be using science to get us fewer of them, not more of them!
...that monkeys have beaten us to cloning
tone
He’ll be the coolest monkey in the jungle.
"The research is costly and can create ethical dilemmas, and primates are also not perfect models of human disease. But the authors of the new study think their new clones could change things.
"Once we demonstrate the cloned monkey's usefulness in curing disease, I hope [Western societies] will gradually change their minds," co-author Mu-ming Poo told Science."
They say they want to change our minds on using primates for research, but they show us pictures of cute baby monkey's sucking their thumbs and cuddling with toys?
I mean, I get they are valuable to research, but those pictures spark an emotional reaction in me to want to stop research on them. I'm conflicted.
It's their leader and they gonna clone it
Because it sounds like something done bu a bunch of CuNTS
I wonder what it's like, being completely unable to feel the suffering of others, and having to pretend to care about the people that you deal with in daily life, all the time. I wonder what hell the poor monkeys used in these sick experiments went through. But all I see here are sociopaths making stupid jokes about it all.
When did you choose to be born human, and not an animal? How did you do that?
...the clone war has
You'll be able to sequence the DNA, error-correct it in software, and 3D-print the DNA before injecting it.
I can imagine simple graphical software that takes your sequenced DNA and lets you apply patches (easier than CRISPR if you have many of them), correct intelligence-linked SNPs, and apply pro-athlete genes, or just randomly fold in DNA sequenced from extraordinary people.