It would be nice if Ford decided that engine mounts lasting more than 30,000 miles should be SOP too. I'm looking at you, Ford/Mazda passenger side mount that was too loose when it was new and now has cracked and burped hydraulic fluid all over everything near it...
When 3D printing finally becomes fast, cheap, and ubiquitous, most things made from printed plastic will be considered cheap, ubiquitous, and ugly, and gauche. If it can be made of wood or metal, people will want it to be made of wood or metal. Cue 3D printing of steel, oak, and maple...
It shouldn't cost more to "rent" a two year old movie to stream online that it does to BUY it in the bargain bin. Not only that, but many older movies aren't available to rent at all, only for "purchase" (which, when bought online is really a long-term rental anyway due to DRM).
Get the rental prices down. Let me pay $2-$3 to watch a movie rather than $6-$10. And for the love of Princess Celestia, when you PAY for content online, it should look good! No compression artifacts, no buffering. Let me pull down the whole thing, or maybe half of it before watching to ensure a good experience.
The point of making movies is to rake in huge profits and transferable tax credits while pretending to have lost money. How does providing you good service at a modest price make the current rights holders richer than they already are?
I guess I'll have to see some people or feed some hungry. Got a bum knee.
Shitty TV is great background for doing physical therapy. (5 shoulder exercises and 3 knee exercises) x 3 sets x 20 reps each x both sides = one episode of Helix.
Hear, hear!! I suppose to the boneheaded CEO, institutional memory means nothing. It is hard to quantify, but without it, your company has no staying power.
Staying power. Is that something that happens before or after the next quarterly earnings statement?
Go after em Nate? More like a struggling website launch is resorting to recycled clickbait to fill in the gaps. Launching shortly before March Madness made perfect sense, but maybe he should have stuck with sports, elections, and "other" instead of trying to generate content in so many areas.
So you have the freedom to make arguments with a lack of evidence while others do not? If your argument is that laws you don't like require evidence from a parallel society that does not and cannot exist you're going to have to use the same standard for laws you accept or cut bait. But don't worry about it: since absolutely no laws have ever met the standards you espouse your argument is pretty much irrelevant outside your own head.
Places that were once ruled by the Ottoman empire you could have whole villages or clans where all males have exactly the same y chromosome and have very high degree of relatedness. Such populations would pledge allegiance to the clan and take great personal sacrifices for the sake of their clans or tribes or villages or their shieks.
Trying to impose a western style democracy of a society with a mean value r on to other societies with an order of magnitude different r would not work easily. Giving autonomy and self governance for people/tribes/clans with high degree of relatedness, but subject to collective punishments and rewards would be considered sacrilege in the West. But such practices are more likely to succeed, pacify the population and lead to peace.
There's an old Bedouin (who were part of the Ottoman empire for a while) saying: "I against my brother, my brothers and I against my cousins, then my cousins and I against strangers"
Tribalism/clannism doesn't bring peace, it just structures violence and corruption differently while removing many of the checks and balances.
The problem with private property rights is that they infringe on civil rights, regardlesss of any good people think private property does. To know that it's beneficial, you'd have to be able to peer into an alternate dimension where private property doesn't exist and our society is otherwise entirely the same. Comparing us to older societies without private property is nonsensical because they were different in a myriad of other fundamental ways. So, where is your scientific, peer-reviewed evidence that private property is beneficial?
Funny, my Android phone uses a common charger. Apple does not, so I don't buy from them (among other reasons). That's how a free market works.
Android phones use a common charger because the EU started pushing for that standard years ago, not because of a free market.
Apple signed on to the micro-usb 5V standard in Europe back in '09 and introduced the necessary adapters a few years later.
People complain all the time about what they think their preferences are, and how they think they work -- when you look at real behaviors though, there is often a disconnect from what people say they will and won't do.
Everyone says, "I never click on ads." While it is obvious that someone does, or else they would abandon the ad model and change for the service.
I think Google's revenue extraction ideal is a presentation of ads that clearly differentiates them from search results but still leads people who avoid ads to click on them anyway when they aren't paying close attention. That's why the ad text and formatting matches the search results. A tiny iconprobably works better for that than a completely different background for most users. Shifting formats around occasionally probably helps too since people will eventually condition themselves to any given format.
Then there's the idea of calling a farm a "conservation community" after placing it in a desert that has already depleted its groundwater, will be getting a shrinking share of the Colorado, and is in the middle of the worst drought in over 100 years. I'd believe the "conservation community" label if they xeriscaped Agritopia as opposed to farming it.
I agree, it is a waste of time to investigate fraud. Every study should be independently replicated to catch all types of false results.
It would be much more expensive to replicate each study than to investigate fraud; in some fields independent replication would be almost as expensive as the original. If we are going to flash anywhere near that amount of cash around I'd rather see grant proposals graded a bit more on bigger sample sizes and internal replication (reviewers could look at applicants' prior publications to see if they follow through on those promises) with funds increased accordingly. NIH could also have requirements for training in experimental design and data analysis for any grad students or postdocs that its grant money pays.
If the prosecutor proved to the judge that you hid assets and used them to pay the lawyer things might get hinky. Might get hinky for the lawyer too since presumably he should have known about the order to freeze assets. I think the "unfreezable" will stay in quotes, at least as far as payments for traceable goods and services go.
The wise man accepts reality and makes the best of it and tries to be a good example.
Exactly. He doesn't fantasize about righteously shooting criminals and vigilanteism, especially not to the point of buying a gun. What kind of example would that set? Hint: imagine someone so creepy they natter on about hoping they get hit by a car 'cause they really really really want to sue someone to bankruptcy/death. Then they launch into a comparative description of which law firms will cause the most damage to the driver. Then they get snippy when you suggest their priorities might be a wee bit off.
When you hear someone vomit nonsense about how much they hope somebody gives them a reason to draw their weapon you are not talking to a gun enthusiast. You're not talking to someone who sees self defense as a necessary tool. You're talking to a gun nut.
A wise man also doesn't carry a loaded gun everywhere, since for most people in most places risks of both violent and property crime are quite low and getting lower. When he does carry it's in a fucking holster, not sharing a pocket with a fucking phone.
Finally: why the hell do they call it a concealed carry permit when 90% of the people who get them seem completely fixated on telling everybody all about their gunnnnzzzzz?
Honestly, it's like the "how can you tell if someone is vegan?" joke, except the concealed carry crowd is worse.
One the one hand that's irrelevant to the topic of the thread (approval hurdles for individualized therapies. On the other hand brincidofovir has yet to succeed in phase III trials' it has also failed a phase II (efficacy) trial, so calling it a life saving drug is a bit premature. On a third hand why are you saying this is about the FDA approval cycle and not about ability to quickly scale up production of the drug to support both a Phase III trial and compassionate use, or the difficulty handing out the drug for compassionate use causes for recruiting patients for a phase III trial? if you think you need the drug, would you rather definitely get it (compassionate use) or risk maybe not getting it (assigned to control wing of clinical trial). On the asinine (money) side, highly publicized failures of a drug during compassionate use could tank a biotech's stock right while they are trying to keep funding together for an expensive clinical trial.
This article covers a bit of the complexities involved:
Slashdot Mirror
this is all part of the regulated market process.
FTFY.
It would be nice if Ford decided that engine mounts lasting more than 30,000 miles should be SOP too. I'm looking at you, Ford/Mazda passenger side mount that was too loose when it was new and now has cracked and burped hydraulic fluid all over everything near it ...
You can do it by phone and fax.
That opens the car; stealing the whole car would still require a truck to move it.
When 3D printing finally becomes fast, cheap, and ubiquitous, most things made from printed plastic will be considered cheap, ubiquitous, and ugly, and gauche. If it can be made of wood or metal, people will want it to be made of wood or metal. Cue 3D printing of steel, oak, and maple ...
Industry shill: contractor
Industry expert: consultant or employee.
Dice will be using drones to deliver movies on flash drives, you say?
It shouldn't cost more to "rent" a two year old movie to stream online that it does to BUY it in the bargain bin. Not only that, but many older movies aren't available to rent at all, only for "purchase" (which, when bought online is really a long-term rental anyway due to DRM).
Get the rental prices down. Let me pay $2-$3 to watch a movie rather than $6-$10. And for the love of Princess Celestia, when you PAY for content online, it should look good! No compression artifacts, no buffering. Let me pull down the whole thing, or maybe half of it before watching to ensure a good experience.
The point of making movies is to rake in huge profits and transferable tax credits while pretending to have lost money. How does providing you good service at a modest price make the current rights holders richer than they already are?
I guess I'll have to see some people or feed some hungry. Got a bum knee.
Shitty TV is great background for doing physical therapy. (5 shoulder exercises and 3 knee exercises) x 3 sets x 20 reps each x both sides = one episode of Helix.
That's why you need to root your fridge. Plus then you can have cooler apps on it.
Hear, hear!! I suppose to the boneheaded CEO, institutional memory means nothing. It is hard to quantify, but without it, your company has no staying power.
Staying power. Is that something that happens before or after the next quarterly earnings statement?
Go after em Nate? More like a struggling website launch is resorting to recycled clickbait to fill in the gaps. Launching shortly before March Madness made perfect sense, but maybe he should have stuck with sports, elections, and "other" instead of trying to generate content in so many areas.
How about going back to the old system: 14 year copyright, extendable for another 14 years?
Anti-SOPA != anti-copyright, something that seems to have escaped the OP.
So you have the freedom to make arguments with a lack of evidence while others do not? If your argument is that laws you don't like require evidence from a parallel society that does not and cannot exist you're going to have to use the same standard for laws you accept or cut bait. But don't worry about it: since absolutely no laws have ever met the standards you espouse your argument is pretty much irrelevant outside your own head.
Places that were once ruled by the Ottoman empire you could have whole villages or clans where all males have exactly the same y chromosome and have very high degree of relatedness. Such populations would pledge allegiance to the clan and take great personal sacrifices for the sake of their clans or tribes or villages or their shieks.
Trying to impose a western style democracy of a society with a mean value r on to other societies with an order of magnitude different r would not work easily. Giving autonomy and self governance for people/tribes/clans with high degree of relatedness, but subject to collective punishments and rewards would be considered sacrilege in the West. But such practices are more likely to succeed, pacify the population and lead to peace.
There's an old Bedouin (who were part of the Ottoman empire for a while) saying: "I against my brother, my brothers and I against my cousins, then my cousins and I against strangers"
Tribalism/clannism doesn't bring peace, it just structures violence and corruption differently while removing many of the checks and balances.
The problem with private property rights is that they infringe on civil rights, regardlesss of any good people think private property does. To know that it's beneficial, you'd have to be able to peer into an alternate dimension where private property doesn't exist and our society is otherwise entirely the same. Comparing us to older societies without private property is nonsensical because they were different in a myriad of other fundamental ways. So, where is your scientific, peer-reviewed evidence that private property is beneficial?
The old EU standard for phones allowed the use of an adapter, which is how Apple met it. Presumably the new standard will as well.
Funny, my Android phone uses a common charger. Apple does not, so I don't buy from them (among other reasons). That's how a free market works.
Android phones use a common charger because the EU started pushing for that standard years ago, not because of a free market. Apple signed on to the micro-usb 5V standard in Europe back in '09 and introduced the necessary adapters a few years later.
People complain all the time about what they think their preferences are, and how they think they work -- when you look at real behaviors though, there is often a disconnect from what people say they will and won't do.
Everyone says, "I never click on ads." While it is obvious that someone does, or else they would abandon the ad model and change for the service.
I think Google's revenue extraction ideal is a presentation of ads that clearly differentiates them from search results but still leads people who avoid ads to click on them anyway when they aren't paying close attention. That's why the ad text and formatting matches the search results. A tiny iconprobably works better for that than a completely different background for most users. Shifting formats around occasionally probably helps too since people will eventually condition themselves to any given format.
Then there's the idea of calling a farm a "conservation community" after placing it in a desert that has already depleted its groundwater, will be getting a shrinking share of the Colorado, and is in the middle of the worst drought in over 100 years. I'd believe the "conservation community" label if they xeriscaped Agritopia as opposed to farming it.
I agree, it is a waste of time to investigate fraud. Every study should be independently replicated to catch all types of false results.
It would be much more expensive to replicate each study than to investigate fraud; in some fields independent replication would be almost as expensive as the original. If we are going to flash anywhere near that amount of cash around I'd rather see grant proposals graded a bit more on bigger sample sizes and internal replication (reviewers could look at applicants' prior publications to see if they follow through on those promises) with funds increased accordingly. NIH could also have requirements for training in experimental design and data analysis for any grad students or postdocs that its grant money pays.
If the prosecutor proved to the judge that you hid assets and used them to pay the lawyer things might get hinky. Might get hinky for the lawyer too since presumably he should have known about the order to freeze assets. I think the "unfreezable" will stay in quotes, at least as far as payments for traceable goods and services go.
The wise man accepts reality and makes the best of it and tries to be a good example.
Exactly. He doesn't fantasize about righteously shooting criminals and vigilanteism, especially not to the point of buying a gun. What kind of example would that set? Hint: imagine someone so creepy they natter on about hoping they get hit by a car 'cause they really really really want to sue someone to bankruptcy/death. Then they launch into a comparative description of which law firms will cause the most damage to the driver. Then they get snippy when you suggest their priorities might be a wee bit off.
When you hear someone vomit nonsense about how much they hope somebody gives them a reason to draw their weapon you are not talking to a gun enthusiast. You're not talking to someone who sees self defense as a necessary tool. You're talking to a gun nut.
A wise man also doesn't carry a loaded gun everywhere, since for most people in most places risks of both violent and property crime are quite low and getting lower. When he does carry it's in a fucking holster, not sharing a pocket with a fucking phone.
Finally: why the hell do they call it a concealed carry permit when 90% of the people who get them seem completely fixated on telling everybody all about their gunnnnzzzzz?
Honestly, it's like the "how can you tell if someone is vegan?" joke, except the concealed carry crowd is worse.
This article covers a bit of the complexities involved:
http://pipeline.corante.com/ar...