An abusive use of antibiotics, causing autoimmunities may very well be a contributing factor.
Regressive Autism May Be Linked to Autoimmune Enteropathy
NEW YORK (MedscapeWire) Apr 30 -- A regressive type of autism described in the April issue of Molecular Psychiatry may have an autoimmune basis, either directly or indirectly from an autoimmune enteropathy.
"We report findings of a novel form of enteropathy in children with autism, characterized by lymphocytic infiltration, increased crypt cell proliferation and enterocyte numbers, with co-localization of IgG and complement C1q on the enterocyte basolateral membrane," write F. Torrente, from Royal Free and University College Medical School in London, United Kingdom, and colleagues.
This comparative histologic study examined children with a form of autism characterized by regression in the second year of life after apparently normal early development. Earlier reports of immunologic abnormalities and unexpected bowel pathology in autistic children have come from this subgroup of affected patients. In this study, the researchers compared duodenal biopsies from 25 autistic children of this type with those from 11 children with celiac disease, 5 with cerebral palsy and mental retardation, and 18 histologically normal controls.
Compared with the normal and cerebral palsy control patients, the autistic children had increased numbers of enterocytes and Paneth cells, increased lymphocyte infiltration in epithelium and lamina propria, and upregulated crypt cell proliferation. Compared with those with celiac disease, the autistic children had fewer intraepithelial lymphocytes and lamina propria cells and more lamina propria T-cell populations. In 23 of 25 autistic children, but in none of the other subjects, there was IgG deposition on the basolateral epithelial surface, co-localizing with complement C1q.
Although these findings support an autoimmune basis for the unexpected bowel abnormalities in children with autism, the authors question the relevance of these findings to the general autistic population, because these children had more obvious bowel symptoms than are typically reported.
Interestingly, however, some children with regressive autism respond to enteric therapy. The bowel changes could also reflect a genetic condition affecting several systems, with brain symptoms more obvious than gastrointestinal symptoms. Although further research is needed to clarify the role of the "gut-brain axis" in autism, autoimmune mechanisms may suggest avenues for future treatment.
"It is possible that in the future there will be such a concept as 'autoimmune autism' within the autism spectrum," J. Licinio and colleagues from the University of California, Los Angeles, write in an accompanying editorial. "Other biological alterations may be the hallmarks of distinct disorders that may emerge from within our current classification of autism."
Hi there! My name is Stannus J. Wolfieschlegelsteinnerbergerdorfmann and I switched from Linux and Mac to Windows because I am a blithering idiot that barely knows how to turn my computer on. And I like the Tellytubby start-up screen, which brings back good memories of my stay at a rehabilitation program for the cowardly. I simply LuuuuV Microsoft products because I have learned to love the torturer, humbly accepting all abuse. With each surprise announcement of a new security breach concerning M$ or whenever Monopolosoft is caught in another lie, I simply turn all three of my other cheeks. I love Bill Gates because is hurts sooooo good!
Yep!!! You've got the right idea! I just can't wait for the Windiots to moderate me! I should end up with a score about as high as the IQ's of the deadheads that use M$ products. If it wasn't a kiddy game designed for their favorite TellyTubbesque Operating System, they would never go for passport.
Don't the fartheads at Monopolosoft know that people actually use Linux to stay away from their SlopWare designes for borderline idiots? Do they not know that their Fascist protocols do not interest the truly free?
The Slime will not share the secrets of their superficial SlimeWare. There attitude is: we ARE the law, and if you don't like that, the Slime Police will slip you away.
NOTICE: MS Corp is looking for spineless, ignorant, sell-outs to lie about why they just love Windows XP. We will only use people who have no clue as to what Open Source is. Applicants must have no ethical standards at all, in other words, they must reflect the total lack of morality and justice demonstrated by Microsoft Corp. for the last 15 years. If accepted, the "user" will be presented with one of Bill Gates' shoes to lick and a photo of his ass to kiss. Monetary compensation is also possible, depending on the quality of the lies.
This proves once again that Microsoft cannot do a single thing honestly. Their corporate culture is so imbibed in lies, illegalities, borderline and otherwise, outrageous affronts to the intelligence of the Windows user base, that they keep stuffing their corporate asses into their own mouths. What surprises me after all these years of abuse on all levels from lies about security, deliberate sabotage of third party soft, stealing of code, is that they actually have a "following" of users, BinLaden included right alongside of Bush and Grandma down the street willing to defend them and kiss Billy"s ass just because he is rich enough to be their god or they find it an absolute necessity to play a few games. This doesn't say much for either the intelligence or the courage of the "average" user.
Yes indeed!! XP is more interesting too! You get to use software that cannot be deleted, no matter how hard you try! That's an advantage if you have mean little kids who like to delete stuff. And you get to use soft that you would never see on a secure system, like snortin' Norton Anti-creepy-crawlies, and McLaughee laughware. You get to download patches every week too! What fun, especially on a 56K connection. And the best of all is that you get to contribute to a monopoly owned by a megalomanic wimp and presided over by a balding red-neck, lying, rather Ballmy type who loves to dance on stage and lie about Open Source, spread FUD and crush the competition illegally! Yes indeed, M$ is more fun.
Evidently, the author, and I use the word loosely, never heard of the Apple Developer Connection! Apple is most cooperative, at least to me, and I'm just a nobody developer for Darwin......
First of all, we let the pig-facedmotherfuckinusedcarandinsurance salesmen enter unto the internet so that they may attempt to dictate their piggish rules to freedom lovers while selling their wares! Then the motherfuckingpoliticianpig-faced mothers followed. What do you expect? This post is NOT a flame!!!! It is an epression of outrage! What do you expect when SUITS take control??????? They should all tighten their ties until they turn as blue as their pig noses!!
You have a good point!!!!! I have never seen Linux run so well on a machine as YellowDog on an iBook. There is also the Gentoo option, but I find it a bit glitchy. I have tried them all and Yellow Dog seems to be the nicest and fastest. The speed is simply unbelievable!!!!!!! I do not believe Mandrake PPC is an option because they will stop their PPC project soon. YellowDog is doing well, and their updates are well maintained.
If you do install Darwin 6.0.1 [just released], I recommend going this route http://developer.apple.com/darwin/projects/darwin/ and not the Fink route. Any method requires the Apple Developer Tools which installs a BSD SubSystem on OS X. I have used both the Fink-based and the "pure" Darwin-based systems and the method to which the link above points is by far the fastest and less glitchy of the two. Don't let that "glitchy" scare you! Darwin works much better than Red Hat, for one example, is easier to update, and had the newest versions of virtually all apps.
I made the switch rather easily. Under OS X, on my humble iBook, I regularly use several Browsers[iCab, Chimera, Mozilla1.1, OnniWeb, Opera 6. IE is there somewhere in the system too, but I never use it. I installed Darwin via Fink and I also may simultaneously use XFree and Aqua. I have KDE, Gnome, WindowMaker, Xfce, IceWM, Blackbox, Enlightenment.... all the latest versions. OpenOffice of course, is a must. In spite of the fact I have the same environments and apps as a Linux distro, I find myself using OS X more exclusively. It suffices for all my needs except for Open Office, which will be coming shortly for OS X.
The iBook is simply the best little machine I have ever owned.
This guy has done more for FreeSoft and OpenSource than us geeks. Let him keep speaking! The fact that most users in the world use MShit means that we all have to worry about the fundemental intelligence of everyone.
Slashdot Mirror
Because he speaks the truth, and as you know, Microslop apologists are afraid of that!
"I saw the best minds of my generation......etc" .....what would happen during power outages?
outage
n 1: the amount of something (as whiskey or oil) [OR MINDS] lost in storage
or transportation.....
Well, that's where a good tape drive comes in handy!
How else would I find out what my mother does at work?
Well, most people I know could put their minds on floppies, and it would still leave enough space for a nice copy of FDISK........... [fmind?]
An abusive use of antibiotics, causing autoimmunities may very well be a contributing factor.
Regressive Autism May Be Linked to Autoimmune Enteropathy
NEW YORK (MedscapeWire) Apr 30 -- A regressive type of autism described in the April issue of Molecular Psychiatry may have an autoimmune basis, either directly or indirectly from an autoimmune enteropathy.
"We report findings of a novel form of enteropathy in children with autism, characterized by lymphocytic infiltration, increased crypt cell proliferation and enterocyte numbers, with co-localization of IgG and complement C1q on the enterocyte basolateral membrane," write F. Torrente, from Royal Free and University College Medical School in London, United Kingdom, and colleagues.
This comparative histologic study examined children with a form of autism characterized by regression in the second year of life after apparently normal early development. Earlier reports of immunologic abnormalities and unexpected bowel pathology in autistic children have come from this subgroup of affected patients. In this study, the researchers compared duodenal biopsies from 25 autistic children of this type with those from 11 children with celiac disease, 5 with cerebral palsy and mental retardation, and 18 histologically normal controls.
Compared with the normal and cerebral palsy control patients, the autistic children had increased numbers of enterocytes and Paneth cells, increased lymphocyte infiltration in epithelium and lamina propria, and upregulated crypt cell proliferation. Compared with those with celiac disease, the autistic children had fewer intraepithelial lymphocytes and lamina propria cells and more lamina propria T-cell populations. In 23 of 25 autistic children, but in none of the other subjects, there was IgG deposition on the basolateral epithelial surface, co-localizing with complement C1q.
Although these findings support an autoimmune basis for the unexpected bowel abnormalities in children with autism, the authors question the relevance of these findings to the general autistic population, because these children had more obvious bowel symptoms than are typically reported.
Interestingly, however, some children with regressive autism respond to enteric therapy. The bowel changes could also reflect a genetic condition affecting several systems, with brain symptoms more obvious than gastrointestinal symptoms. Although further research is needed to clarify the role of the "gut-brain axis" in autism, autoimmune mechanisms may suggest avenues for future treatment.
"It is possible that in the future there will be such a concept as 'autoimmune autism' within the autism spectrum," J. Licinio and colleagues from the University of California, Los Angeles, write in an accompanying editorial. "Other biological alterations may be the hallmarks of distinct disorders that may emerge from within our current classification of autism."
...now /. lets capatalist pigs post too!
No, you are wrong! It is your attitude that is the cause of the Enrons of the world because it defends the immorality of an immoral corporation.
Hi there! My name is Stannus J. Wolfieschlegelsteinnerbergerdorfmann and I switched from Linux and Mac to Windows because I am a blithering idiot that barely knows how to turn my computer on. And I like the Tellytubby start-up screen, which brings back good memories of my stay at a rehabilitation program for the cowardly. I simply LuuuuV Microsoft products because I have learned to love the torturer, humbly accepting all abuse. With each surprise announcement of a new security breach concerning M$ or whenever Monopolosoft is caught in another lie, I simply turn all three of my other cheeks. I love Bill Gates because is hurts sooooo good!
Yep!!! You've got the right idea! I just can't wait for the Windiots to moderate me! I should end up with a score about as high as the IQ's of the deadheads that use M$ products. If it wasn't a kiddy game designed for their favorite TellyTubbesque Operating System, they would never go for passport.
Don't the fartheads at Monopolosoft know that people actually use Linux to stay away from their SlopWare designes for borderline idiots? Do they not know that their Fascist protocols do not interest the truly free?
The Slime will not share the secrets of their superficial SlimeWare. There attitude is: we ARE the law, and if you don't like that, the Slime Police will slip you away.
NOTICE: MS Corp is looking for spineless, ignorant, sell-outs to lie about why they just love Windows XP. We will only use people who have no clue as to what Open Source is. Applicants must have no ethical standards at all, in other words, they must reflect the total lack of morality and justice demonstrated by Microsoft Corp. for the last 15 years. If accepted, the "user" will be presented with one of Bill Gates' shoes to lick and a photo of his ass to kiss. Monetary compensation is also possible, depending on the quality of the lies.
This proves once again that Microsoft cannot do a single thing honestly. Their corporate culture is so imbibed in lies, illegalities, borderline and otherwise, outrageous affronts to the intelligence of the Windows user base, that they keep stuffing their corporate asses into their own mouths. What surprises me after all these years of abuse on all levels from lies about security, deliberate sabotage of third party soft, stealing of code, is that they actually have a "following" of users, BinLaden included right alongside of Bush and Grandma down the street willing to defend them and kiss Billy"s ass just because he is rich enough to be their god or they find it an absolute necessity to play a few games. This doesn't say much for either the intelligence or the courage of the "average" user.
Yes indeed!! XP is more interesting too! You get to use software that cannot be deleted, no matter how hard you try! That's an advantage if you have mean little kids who like to delete stuff. And you get to use soft that you would never see on a secure system, like snortin' Norton Anti-creepy-crawlies, and McLaughee laughware. You get to download patches every week too! What fun, especially on a 56K connection. And the best of all is that you get to contribute to a monopoly owned by a megalomanic wimp and presided over by a balding red-neck, lying, rather Ballmy type who loves to dance on stage and lie about Open Source, spread FUD and crush the competition illegally! Yes indeed, M$ is more fun.
GNU GNOW it!!!!
I am Chaos.
I am the substance from which
your artists and scientists build rhythms.
I am the spirit with which
your children and clowns
laugh in happy anarchy.
I am Chaos.
I am alive, and tell you
that you are free.
-Eris, Goddess of Chaos, Discord, and Confusion...
GNUness gracious! Gnuys! I'm GNUnna try it right GNUow.
....so there! Nyaa nyaaa nyaaaaaa
The FreeBSD handbook, available for free on the web, contains more useful Unix information pertaining to OS X than this book.
Evidently, the author, and I use the word loosely, never heard of the Apple Developer Connection! Apple is most cooperative, at least to me, and I'm just a nobody developer for Darwin......
First of all, we let the pig-facedmotherfuckinusedcarandinsurance salesmen enter unto the internet so that they may attempt to dictate their piggish rules to freedom lovers while selling their wares! Then the motherfuckingpoliticianpig-faced mothers followed. What do you expect? This post is NOT a flame!!!! It is an epression of outrage! What do you expect when SUITS take control??????? They should all tighten their ties until they turn as blue as their pig noses!!
You have a good point!!!!! I have never seen Linux run so well on a machine as YellowDog on an iBook. There is also the Gentoo option, but I find it a bit glitchy. I have tried them all and Yellow Dog seems to be the nicest and fastest. The speed is simply unbelievable!!!!!!! I do not believe Mandrake PPC is an option because they will stop their PPC project soon. YellowDog is doing well, and their updates are well maintained.
If you do install Darwin 6.0.1 [just released], I recommend going this route http://developer.apple.com/darwin/projects/darwin/ and not the Fink route. Any method requires the Apple Developer Tools which installs a BSD SubSystem on OS X. I have used both the Fink-based and the "pure" Darwin-based systems and the method to which the link above points is by far the fastest and less glitchy of the two. Don't let that "glitchy" scare you! Darwin works much better than Red Hat, for one example, is easier to update, and had the newest versions of virtually all apps.
I made the switch rather easily. Under OS X, on my humble iBook, I regularly use several Browsers[iCab, Chimera, Mozilla1.1, OnniWeb, Opera 6. IE is there somewhere in the system too, but I never use it. I installed Darwin via Fink and I also may simultaneously use XFree and Aqua. I have KDE, Gnome, WindowMaker, Xfce, IceWM, Blackbox, Enlightenment.... all the latest versions. OpenOffice of course, is a must. In spite of the fact I have the same environments and apps as a Linux distro, I find myself using OS X more exclusively. It suffices for all my needs except for Open Office, which will be coming shortly for OS X.
The iBook is simply the best little machine I have ever owned.
This guy has done more for FreeSoft and OpenSource than us geeks. Let him keep speaking! The fact that most users in the world use MShit means that we all have to worry about the fundemental intelligence of everyone.