Sorta what you said, but also not. From the article you linked
The second step of virus entry and the first absolutely required for infection entails binding of Env to its primary receptor,the host protein CD4 (Maddon et al. 1986; McDougal et al. 1986). Env is a heavily glycosylated trimer of gp120 and gp41 heterodimers.
Note the "absolutely required"
The third step of virus entry, coreceptor binding, is widely thought to be the trigger that activates the membrane fusionpotential of Env. HIV strains can be broadly classified based on their coreceptor usage. Viruses that use the chemokine receptor CCR5 are termed R5 HIV, those that use CXCR4 are termed X4 HIV, and viruses that can use both coreceptors are called R5X4HIV (Berger et al. 1998). There is no compelling evidence that coreceptors other than CCR5 and CXCR4 play important roles in supporting infection of HIV-1 in vivo. With rare exception, only R5 and R5X4 viruses are transmitted between individuals (Keele et al. 2008), likely owing to multiple imperfect but overlapping host restrictions on X4 HIV transmission (reviewed in Margolis and Shattock 2006).
The NPR.org article says that the researcher blocked the CCR5 pathway, So if the father has the R5 or R5X4 HIV variant, then the genetic modification will indeed prevent the daughter's getting infected from their dad. If I recall correctly, this "fix" would also cause the daughters to be immune to the bubonic plague (Yersinia pestis). I suspect that what he did was copy the CCR5 delta 32 mutation into the embryo. it's a mutation known not to be harmful.
In my dream world, this would be used to silently propel solar-powered zeppelins around the world. The zeppelin's buoyancy would support the weight of the batteries used for night-time propulsion. Of course the problem with that is lithium batteries well-known flammability. But what's the odds of something going wrong with something a simple as a zeppelin?
we still should acknowledge that there are telemarketers who do have humanity
False. Anyone who signs up to do this job accepts the shit storm they will receive. You don't get to say "I'm just doing my job." Find a different job.
agreed regarding killing rats, PETA says "rats are living creatures and deserve our protection as well". So rats should be treated like people. If a person came into my house and gnawed open my cereal box and shit on the kitchen counter, I'm a gonna shoot him if I catch him.
If a rat started ringing my phone all day and I could catch him, would I just say "oh well, let it go. it's a living creature". uh, no.
Whoever wrote the Slashdot summary should have taken the few seconds to read the abstract they linked to. From that abstract, here's the author's claim regarding contamination.
To eliminate the possibility that the presence of bacteria was due to contamination, we examined germ free mouse brains (n=4) processed in an identical way; we did not detect any bacteria. The observation that the location of the bacteria was highly specific and deep within the specimens also argues against contamination. Interestingly, there were no structural signs of inflammation in any of the brains examined. It is presently unclear the route of entry bacteria take to the brain, but the evidence of them in axons and at the blood brain barrier supports previous speculation.
It's not confusing, it's just that many people don't do the conversion in their heads. Further, presenting the natural frequency is more useful for small percentages: e.g. 1 in 4,000 is definitely easier to digest than 0.025%
1. What "conversion"?
2. What makes "1 in 4,000" easier to digest than "0.025%"?
I suppose it's because.025% is a poor choice of a way to express a value. Percent means parts of a hundred, and they make more sense when the values is between 1 and 100. When you're using percents that are far less than 1%, it is hard to get an intuitive feel for the relative size of whatever is being measured. Sure it's easy enough to do the conversion, but why not express it as a number that is scaled to the measurement in the first place.
It's sort of like when someone asked for the height of my son. I could say he is 0.0011 mile tall, and although you may have a good feeling for how long a mile is, you have no idea whether he is average, short, or tall until you've done the conversion.
Here's your answer: No, I won't take on liability if my device is used in the attack due to a poor design decision made by the manufacturer. The manufacturer is especially liable if the flaw is a well-known and solved security issue that they chose to ignore, such as using hard-coded default passwords and backdoor accounts.
You want your cake and eat it. So typical - screaming for your individual rights, wilfully blind to any personal responsibility. Fuck you asshole, governments exist precisely to protect us from the dickheads like you.
Seriously, why do you think that a purchaser of a defective product be the one held liable and not the manufacturer? You should consider that it is settled case law that the builder is responsible for hidden defects, not the purchaser, and this goes back to the Code Of Hammurabi.
You didn't answer his question : will you take on the liability if your device is used to attack a 3rd party?
Here's your answer: No, I won't take on liability if my device is used in the attack due to a poor design decision made by the manufacturer. The manufacturer is especially liable if the flaw is a well-known and solved security issue that they chose to ignore, such as using hard-coded default passwords and backdoor accounts.
IANAL, nor do I regularly read legislature bills. But, on my read of the bill, I don't see any teeth to the bill? What are the repercussions for a company for violating this law? Other than setting a more concrete bar for possible civil cases, are there any more repercussions?
If a bill don't have teeth, what's the point?
Without the law if you buy an IoT device that gets hacked and captures enough information that lets your bank accounts get compromised, that's your tough luck.
With the law, if people have their devices hacked through a fixed password and financial losses occur, then there's a basis for a lawsuit: "You broke the law and thus it is your fault this bad thing happened". And it can even be a class-action suit and make some law firm partners even richer.
I setup a Facebook account over 10 years ago using a throw-away email account and a phony birthdate. The only real info was my actual name. I forgot my password, and Facebook is no help. How do I contact these dark web people to get my password? For only $3, it's a bargain.
Well, yeah, you're right about that. I have had to once share the weekday show with members of the permanently unemployed nothing-to-lose underclass who felt a need to act out. Also, one is more likely on a weekday to get stale popcorn, although I stopped buying that quite some time ago.
What you say is true, "The phone system's been outright ruined by spammers".
Not answering is my default mode as well as turning the phone off. But not everyone has the option of not answering, especially small business owners.
I recently hired a local guy who does remodeling and home repair to do some work for me. I asked him about getting scam calls on his phone seeing how the number was published, and he has to take every call if he wants any business. His phone rang often, and often while he was on the ladder, or the roof, or while running the saw, or while just standing there. He said "Yeah, it's a problem". The look on his face made me wonder if his head was about to explode.
His solution seems to be to let unknown calls go to voicemail, and if it turned out to be a prospective customer, add the number to his contacts. He still has to stop and look at the phone because if it is an existing customer, giving good service to customers requires that he answer those calls right then, which in an ideal world would be fine. And he still has to wade through the bogus voicemail messages spammers often leave.
Also, this guy and his workers were large. I'd pay for their airline tickets if they ever wanted to go over there and visit one of those call centers with some baseball bats. I bet people would pay to see a video of that in movie theaters.
Force the telcos to not allow callerID spoofing of any kind. It's gooten out of hand In theory, it allows a company to have a representative call you, but their phone number is spoofed to give the general contact number instead of that person's desk. It made sense back then, but almost every single callerID spoofed number is a scam. Just stop allowing callerID spoofing. We don't need it as much as we need relief.
The law requires that people be able to use callerID blocking, So businesses that do not want you to call back on the number that called you can block it, and they can say in the conversation, or voice mail, what number to call them back on.
This article tells us how far the surveillance state has already gone.
Here's an AI doing something "useful"
Since the spring of 2017, the information has been used to rank citizens' "trustworthiness"
Who are us to tell the Indians what they ought to do?
If the Indians want to be ranked for 'trustworthiness' it's their right to do so !!
That is so true, it is their right to do so, and likewise for China. If that is what they want to do to solve their problems, then that is indeed their business. But, and it's a big but, what constitutes the "they" who want to do these things? The average man on the street in Mumbai or Beijing? or some government agency?
But first of all, I'm interested in all this for the implications it has for my country, and not so much other places. We've got the same problem in the USA. There have always been (I'm talking historically) those in power who do things to us that we don't want "they" to do, even though we are part of that they. And I don't doubt for one second that there's people in power in the USA that thinks putting the owner's QR code on every gun in the USA is a good idea. That one is already being bandied about in California in an indirect fashion. And consider the push to put backdoors into all encryption. They definitely want that, but that they is not the they that I want to be part of.
Since the spring of 2017, the information has been used to rank citizens’ “trustworthiness” using various criteria. People are deemed trustworthy, average or untrustworthy depending on how they fit into the following categories: 15 to 55 years old (ie, of military age); Uighur (the catalogue is explicitly racist: people are suspected merely on account of their ethnicity); unemployed; have religious knowledge; pray five times a day (freedom of worship is guaranteed by China’s constitution); have a passport; have visited one of 26 countries; have ever overstayed a visa; have family members in a foreign country (there are at least 10,000 Uighurs in Turkey); and home school their children. Being labelled “untrustworthy” can lead to a camp.
And your identity card will contain your "reliability status"
Next, the records associated with identity cards can contain biometric data including fingerprints, blood type and DNA information as well as the subject’s detention record and “reliability status”.
How shall we gather the information? This is way beyond Orwellian.
To complete the panorama of human surveillance, the government has a programme called “becoming kin” in which local families (mostly Uighur) “adopt” officials (mostly Han). The official visits his or her adoptive family regularly, lives with it for short periods, gives the children presents and teaches the household Mandarin. He also verifies information collected by fanghuiju teams. The programme appears to be immense. According to an official report in 2018, 1.1m officials have been paired with 1.6m families. That means roughly half of Uighur households have had a Han-Chinese spy/indoctrinator assigned to them.
Have a cellphone?
Because the government sees what it calls “web cleansing” as necessary to prevent access to terrorist information, everyone in Xinjiang is supposed to have a spyware app on their mobile phone. Failing to install the app, which can identify people called, track online activity and record social-media use, is an offence. “Wi-Fi sniffers” in public places keep an eye, or nose, on all networked devices in range.
Don't have a phone? How you'll be tracked.
In Hotan and Kashgar there are poles bearing perhaps eight or ten video cameras at intervals of 100-200 metres along every street; a far finer-grained surveillance net than in most Chinese cities. As well as watching pedestrians the cameras can read car number plates and correlate them with the face of the person driving. Only registered owners may drive cars; anyone else will be arrested, according to a public security official who accompanied this correspondent in Hotan.
Wondering about controlling weapons?
In butchers and restaurants all over Xinjiang you will see kitchen knives chained to the wall, lest they be snatched up and used as weapons. In Aksu QR codes containing the owner’s identity-card information have to be engraved on every blade.
$5 for a homebrew antenna? That's pure luxury! I make mine from Pringles cans. They were on sale last week at 99 cents per can so I bought 50 of them.
I make my kids hold up some wires and aluminum tubes, and they rotate on command to pick of channels from different directions. They can even get on the roof for those more distant channels. However, they have incurred more expense than the $5 you mentioned.
Slashdot Mirror
Sorta what you said, but also not.
From the article you linked
The second step of virus entry and the first absolutely required for infection entails binding of Env to its primary receptor,the host protein CD4 (Maddon et al. 1986; McDougal et al. 1986). Env is a heavily glycosylated trimer of gp120 and gp41 heterodimers.
Note the "absolutely required"
The third step of virus entry, coreceptor binding, is widely thought to be the trigger that activates the membrane fusionpotential of Env. HIV strains can be broadly classified based on their coreceptor usage. Viruses that use the chemokine receptor CCR5 are termed R5 HIV, those that use CXCR4 are termed X4 HIV, and viruses that can use both coreceptors are called R5X4HIV (Berger et al. 1998). There is no compelling evidence that coreceptors other than CCR5 and CXCR4 play important roles in supporting infection of HIV-1 in vivo. With rare exception, only R5 and R5X4 viruses are transmitted between individuals (Keele et al. 2008), likely owing to multiple imperfect but overlapping host restrictions on X4 HIV transmission (reviewed in Margolis and Shattock 2006).
The NPR.org article says that the researcher blocked the CCR5 pathway, So if the father has the R5 or R5X4 HIV variant, then the genetic modification will indeed prevent the daughter's getting infected from their dad.
If I recall correctly, this "fix" would also cause the daughters to be immune to the bubonic plague (Yersinia pestis). I suspect that what he did was copy the CCR5 delta 32 mutation into the embryo. it's a mutation known not to be harmful.
I forgot to ask, how well would this work in the rain? Or even fog for that matter.
In my dream world, this would be used to silently propel solar-powered zeppelins around the world. The zeppelin's buoyancy would support the weight of the batteries used for night-time propulsion.
Of course the problem with that is lithium batteries well-known flammability. But what's the odds of something going wrong with something a simple as a zeppelin?
we still should acknowledge that there are telemarketers who do have humanity
False. Anyone who signs up to do this job accepts the shit storm they will receive. You don't get to say "I'm just doing my job." Find a different job.
agreed
regarding killing rats, PETA says "rats are living creatures and deserve our protection as well".
So rats should be treated like people. If a person came into my house and gnawed open my cereal box and shit on the kitchen counter, I'm a gonna shoot him if I catch him.
If a rat started ringing my phone all day and I could catch him, would I just say "oh well, let it go. it's a living creature". uh, no.
Whoever wrote the Slashdot summary should have taken the few seconds to read the abstract they linked to. From that abstract, here's the author's claim regarding contamination.
To eliminate the possibility that the presence of bacteria was due to contamination, we examined germ free mouse brains (n=4) processed in an identical way; we did not detect any bacteria. The observation that the location of the bacteria was highly specific and deep within the specimens also argues against contamination. Interestingly, there were no structural signs of inflammation in any of the brains examined. It is presently unclear the route of entry bacteria take to the brain, but the evidence of them in axons and at the blood brain barrier supports previous speculation.
I am on the side of adding an hour now so that in 6,000 years everything will be fine.
It's not confusing, it's just that many people don't do the conversion in their heads. Further, presenting the natural frequency is more useful for small percentages: e.g. 1 in 4,000 is definitely easier to digest than 0.025%
1. What "conversion"?
2. What makes "1 in 4,000" easier to digest than "0.025%"?
I suppose it's because .025% is a poor choice of a way to express a value. Percent means parts of a hundred, and they make more sense when the values is between 1 and 100. When you're using percents that are far less than 1%, it is hard to get an intuitive feel for the relative size of whatever is being measured. Sure it's easy enough to do the conversion, but why not express it as a number that is scaled to the measurement in the first place.
It's sort of like when someone asked for the height of my son. I could say he is 0.0011 mile tall, and although you may have a good feeling for how long a mile is, you have no idea whether he is average, short, or tall until you've done the conversion.
dashdotdot dotdashdot dot dashdot dashdotdash
Bzzzt. I hope that the company that makes it can spell better than that.
Ahhhhhh, my bad. But I want to blame slashdot for not having a more universal spell-checker.
I am sad. We can't put Unicode emoticons on Slashdot, and they won't let us post Morse code.
dotdashdot dot dashdash dot dashdash dashdotdotdot dot dotdashdot
dash dashdashdash
dashdotdot dotdashdot dot dashdot dashdotdash
dashdotdashdash dashdashdash dotdotdash dotdashdot
dashdashdash dotdotdotdash dotdash dotdashdotdot dash dotdot dashdot dot
Here's your answer: No, I won't take on liability if my device is used in the attack due to a poor design decision made by the manufacturer.
The manufacturer is especially liable if the flaw is a well-known and solved security issue that they chose to ignore, such as using hard-coded default passwords and backdoor accounts.
You want your cake and eat it. So typical - screaming for your individual rights, wilfully blind to any personal responsibility. Fuck you asshole, governments exist precisely to protect us from the dickheads like you.
Seriously, why do you think that a purchaser of a defective product be the one held liable and not the manufacturer?
You should consider that it is settled case law that the builder is responsible for hidden defects, not the purchaser, and this goes back to the Code Of Hammurabi.
You didn't answer his question : will you take on the liability if your device is used to attack a 3rd party?
Here's your answer: No, I won't take on liability if my device is used in the attack due to a poor design decision made by the manufacturer.
The manufacturer is especially liable if the flaw is a well-known and solved security issue that they chose to ignore, such as using hard-coded default passwords and backdoor accounts.
IANAL, nor do I regularly read legislature bills. But, on my read of the bill, I don't see any teeth to the bill? What are the repercussions for a company for violating this law? Other than setting a more concrete bar for possible civil cases, are there any more repercussions?
If a bill don't have teeth, what's the point?
Without the law if you buy an IoT device that gets hacked and captures enough information that lets your bank accounts get compromised, that's your tough luck.
With the law, if people have their devices hacked through a fixed password and financial losses occur, then there's a basis for a lawsuit: "You broke the law and thus it is your fault this bad thing happened". And it can even be a class-action suit and make some law firm partners even richer.
If it were my employee that automated their job, I would fire the ones that were still doing everything by hand and keep the obvious intelligent one.
I setup a Facebook account over 10 years ago using a throw-away email account and a phony birthdate. The only real info was my actual name.
I forgot my password, and Facebook is no help.
How do I contact these dark web people to get my password? For only $3, it's a bargain.
TL
You will avoid some of the problems but not all.
Well, yeah, you're right about that.
I have had to once share the weekday show with members of the permanently unemployed nothing-to-lose underclass who felt a need to act out.
Also, one is more likely on a weekday to get stale popcorn, although I stopped buying that quite some time ago.
I didn't read past the OP's "Copying is a natural right". It appears you did, and you have my sympathy.
Go on a weekday during the day, and you'll avoid all that.
I'm aware this advice does not work for wage slaves.
What you say is true, "The phone system's been outright ruined by spammers".
Not answering is my default mode as well as turning the phone off.
But not everyone has the option of not answering, especially small business owners.
I recently hired a local guy who does remodeling and home repair to do some work for me. I asked him about getting scam calls on his phone seeing how the number was published, and he has to take every call if he wants any business. His phone rang often, and often while he was on the ladder, or the roof, or while running the saw, or while just standing there.
He said "Yeah, it's a problem". The look on his face made me wonder if his head was about to explode.
His solution seems to be to let unknown calls go to voicemail, and if it turned out to be a prospective customer, add the number to his contacts. He still has to stop and look at the phone because if it is an existing customer, giving good service to customers requires that he answer those calls right then, which in an ideal world would be fine. And he still has to wade through the bogus voicemail messages spammers often leave.
Also, this guy and his workers were large. I'd pay for their airline tickets if they ever wanted to go over there and visit one of those call centers with some baseball bats. I bet people would pay to see a video of that in movie theaters.
Thought you were missing an 'o'.
It's gooten out of hand
Found it.
Thanks!
I owe you one now.
Force the telcos to not allow callerID spoofing of any kind. It's gooten out of hand
In theory, it allows a company to have a representative call you, but their phone number is spoofed to give the general contact number instead of that person's desk. It made sense back then, but almost every single callerID spoofed number is a scam.
Just stop allowing callerID spoofing. We don't need it as much as we need relief.
The law requires that people be able to use callerID blocking,
So businesses that do not want you to call back on the number that called you can block it, and they can say in the conversation, or voice mail, what number to call them back on.
Whatever steaming pile is on offer from Google, it would be nice if we could at least do away with little-endian hostnames.
That would be an easy fix and probably stop most of the phony sites right there. So it's not going to happen.
This article tells us how far the surveillance state has already gone.
Here's an AI doing something "useful"
Since the spring of 2017, the information has been used to rank citizens' "trustworthiness"
Who are us to tell the Indians what they ought to do?
If the Indians want to be ranked for 'trustworthiness' it's their right to do so !!
That is so true, it is their right to do so, and likewise for China. If that is what they want to do to solve their problems, then that is indeed their business.
But, and it's a big but, what constitutes the "they" who want to do these things?
The average man on the street in Mumbai or Beijing? or some government agency?
But first of all, I'm interested in all this for the implications it has for my country, and not so much other places.
We've got the same problem in the USA. There have always been (I'm talking historically) those in power who do things to us that we don't want "they" to do, even though we are part of that they.
And I don't doubt for one second that there's people in power in the USA that thinks putting the owner's QR code on every gun in the USA is a good idea. That one is already being bandied about in California in an indirect fashion.
And consider the push to put backdoors into all encryption. They definitely want that, but that they is not the they that I want to be part of.
And the new law, that underwear must be changed every half hour
https://www.youtube.com/watch?...
This article tells us how far the surveillance state has already gone.
https://www.economist.com/brie...
Here's an AI doing something "useful"
Since the spring of 2017, the information has been used to rank citizens’ “trustworthiness” using various criteria. People are deemed trustworthy, average or untrustworthy depending on how they fit into the following categories: 15 to 55 years old (ie, of military age); Uighur (the catalogue is explicitly racist: people are suspected merely on account of their ethnicity); unemployed; have religious knowledge; pray five times a day (freedom of worship is guaranteed by China’s constitution); have a passport; have visited one of 26 countries; have ever overstayed a visa; have family members in a foreign country (there are at least 10,000 Uighurs in Turkey); and home school their children. Being labelled “untrustworthy” can lead to a camp.
And your identity card will contain your "reliability status"
Next, the records associated with identity cards can contain biometric data including fingerprints, blood type and DNA information as well as the subject’s detention record and “reliability status”.
How shall we gather the information? This is way beyond Orwellian.
To complete the panorama of human surveillance, the government has a programme called “becoming kin” in which local families (mostly Uighur) “adopt” officials (mostly Han). The official visits his or her adoptive family regularly, lives with it for short periods, gives the children presents and teaches the household Mandarin. He also verifies information collected by fanghuiju teams. The programme appears to be immense. According to an official report in 2018, 1.1m officials have been paired with 1.6m families. That means roughly half of Uighur households have had a Han-Chinese spy/indoctrinator assigned to them.
Have a cellphone?
Because the government sees what it calls “web cleansing” as necessary to prevent access to terrorist information, everyone in Xinjiang is supposed to have a spyware app on their mobile phone. Failing to install the app, which can identify people called, track online activity and record social-media use, is an offence. “Wi-Fi sniffers” in public places keep an eye, or nose, on all networked devices in range.
Don't have a phone? How you'll be tracked.
In Hotan and Kashgar there are poles bearing perhaps eight or ten video cameras at intervals of 100-200 metres along every street; a far finer-grained surveillance net than in most Chinese cities. As well as watching pedestrians the cameras can read car number plates and correlate them with the face of the person driving. Only registered owners may drive cars; anyone else will be arrested, according to a public security official who accompanied this correspondent in Hotan.
Wondering about controlling weapons?
In butchers and restaurants all over Xinjiang you will see kitchen knives chained to the wall, lest they be snatched up and used as weapons. In Aksu QR codes containing the owner’s identity-card information have to be engraved on every blade.
$5 for a homebrew antenna? That's pure luxury! I make mine from Pringles cans. They were on sale last week at 99 cents per can so I bought 50 of them.
I make my kids hold up some wires and aluminum tubes, and they rotate on command to pick of channels from different directions. They can even get on the roof for those more distant channels.
However, they have incurred more expense than the $5 you mentioned.