Replicating chemistry isn't hard with good instructions.
Organic chemists often lump reactions into two classes: peak reactions and plateau reactions. Peak reactions give a maximum yield of product only for a narrow range of conditions. Plateau reactions work over a broad range of conditions. If you go to run a plateau reaction, you don't need a very good SOP, but if you are running a peak reaction you need very specific conditions and detailed instructions for every step. And you generally don't know what type of reaction you are going to have on your hands just by looking at it on paper.
A scientist should also run experiments multiple times to see if the results are repeatable before publishing those results.
No time. Many if not most synthetic methodology papers will test a new reaction on a range of homologous compounds, say 20. Few of those are repeated twice, let alone multiple times. A lot of this work comes out of graduate school groups where the emphasis is on publishing rapidly. There is one Nobel Prize winner in particular whose publications in Tetrahedron Letters (usually a two page paper) are notorious for sacrificing accuracy for rapidity.
In meatspace war, the object was always to damage flesh. We first had blunt objects (stones, clubs) which gave way to sharp piercing weapons (spears, arrows) which gave way to propelled metal (flintlocks, rifles) which gave way to blast waves and shrapnel (shells, bombs) which evolved into directable versions (cruise missiles, armed drones). The next step is probably autocontrolled weapons v1.0, iRobots which scurry through the battlefield and club the enemy or some such.
I wonder where we are on that scale with weaponizable viruses. Are Stuxnet and its peers the equivalent of Predator drones or will we look back decades from now and think that they were the crude matchlock blunderbusses of their day?
Cornyn should shut his fat hypocritic yap. It's his kind that wants to make IP abuse a criminal matter where it should be civil. He's in the crowd who would make violation of TOSs a federal crime. Now he is crying crocodile tears that the Justice Department applied laws he rabidly supported?
It would seem that - with isolated exceptions - having wealth is a get out of responsibility free card. Society generally is more forgiving of the transgressions of the wealthy than of the working class.
This has been the way of the world since... well, forever.
This may be one of the times where we underestimate the ability of the masses to cope with selective information. After all, America's Funniest Home Videos has been on the air for over twenty years and people have adjusted to not having grooms collapse at every wedding and nutsacks being pummeled by every wiffle ball hit.
Indeed. Annoying as hell that they decided to fix one flawed process by instituting another even more flawed process.
If you think about some of the high money contracts it covers, it makes a lot of sense. You want to pave 100 miles of road, you put our specifications for asphalt depth, quality, etc. - all the parameters covering the needed job. Then let all bid on the job. This eliminates somebody's brother in law from getting the contract unless he is the lowest bidder willing to meet the specs.
Where is fails is on the cutting edge of technology. Those potholes on the parkway that appear in the same place every winter and are filled the same way every spring? There are advanced paving methods and materials which could prevent them from forming in the first place but government bidding laws prevent the contract from going to a higher bidder who wants to use experimental technology.
That's because in the US people are trained to always go with the lowest bidder and to only look at the short term return on an investment. My dad was a high-quality remodeler for many years, and it was always a challenge for him to make a customer understand that the guy with the lowest bid was not always the best choice.
Remember that the government "lowest bidder" laws were put into place in response to rampant and blatant contract-fixing. In the private sector, you get what you pay for usually.
"I'm going to be late to the cross burning, my free government blowjob robot broke. farkin' bullshiat man, this guy's the worst president ever. Just like a black guy to give you a blowjob robot for free and it breaks after six years." -Patton Oswalt
I picked up a Windows 8 touch Samsung notebook. Very nice design. When I did this, Windows 8 was no longer the OS I disliked - quite the opposite. Many common things that I used to have to do, (like adjust network settings) were such a chore with the mouse or keyboard..... Reminds me of when the mouse got real popular.
Nice try. On the second day of astroturf training you will learn to create a real user ID to give you more credibility than just some AC.
Great. Here come the tsunami of middle-aged and elderly users - who were formerly able to rest their wrists on the laptop and type but who now have to lift up their arms to touch the screen constantly - with their complaints as the new interface slowly destroys what was left of their rotator cuffs and shoulder bursas.
Now who can argue with that? I think we're all indebted to Anonymous Coward for clearly stating what needed to be said. I'm particulary glad that these lovely children were reading Slashdot today to read that speech. Not only was it authentic Internet gibberish, it expressed a courage little seen in this day and age.
Do the decision makers at Microsoft not have any rotator cuffs? Because just the thought of reaching out to touch a desktop monitor all day makes mine start to ache.
...actually, being a Canadian, I started giving my life story until she told me to shut up.
Something along the lines of this:
"I don’t reckon them times will ever come again. There never was a more bullier old ram than what he was. Grandfather fetched him from Illinois–got him of a man by the name of Yates–Bill Yates–maybe you might have heard of him; his father was a deacon–Baptist–and he was a rustler, too; a man had to get up ruther early to get the start of old Thankful Yates; it was him that put the Greens up to jining teams with my grandfather when he moved west. Seth Green was prob’ly the pick of the flock; he married a Wilkerson–Sarah Wilkerson–good cretur, she was–one of the likeliest heifers that was ever raised in old Stoddard, everybody said that knowed her. She could heft a bar’l of flour as easy as I can flirt a flapjack. And spin? Don’t mention it! Independent? Humph! When Sile Hawkins come a browsing around her, she let him know that for all his tin he couldn’t trot in harness alongside of her. You see, Sile Hawkins was–no, it warn’t Sile Hawkins, after all–it was a galoot by the name of Filkins–I disremember his first name; but he was a stump–come into pra’r meeting drunk, one night, hooraying for Nixon, becuz he thought it was a primary; and old deacon Ferguson up and scooted him through the window and he lit on old Miss Jefferson’s head, poor old filly. She was a good soul–had a glass eye and used to lend it to old Miss Wagner, that hadn’t any, to receive company in; it warn’t big enough, and when Miss Wagner warn’t noticing, it would get twisted around in the socket, and look up, maybe, or out to one side, and every which way, while t’ other one was looking as straight ahead as a spy-glass. Grown people didn’t mind it, but it most always made the children cry, it was so sort of scary. She tried packing it in raw cotton, but it wouldn’t work, somehow–the cotton would get loose and stick out and look so kind of awful that the children couldn’t stand it no way. She was always dropping it out, and turning up her old dead-light on the company empty, and making them oncomfortable, becuz she never could tell when it hopped out, being blind on that side, you see. So...."
Slashdot Mirror
Replicating chemistry isn't hard with good instructions.
Organic chemists often lump reactions into two classes: peak reactions and plateau reactions. Peak reactions give a maximum yield of product only for a narrow range of conditions. Plateau reactions work over a broad range of conditions. If you go to run a plateau reaction, you don't need a very good SOP, but if you are running a peak reaction you need very specific conditions and detailed instructions for every step. And you generally don't know what type of reaction you are going to have on your hands just by looking at it on paper.
A scientist should also run experiments multiple times to see if the results are repeatable before publishing those results.
No time. Many if not most synthetic methodology papers will test a new reaction on a range of homologous compounds, say 20. Few of those are repeated twice, let alone multiple times. A lot of this work comes out of graduate school groups where the emphasis is on publishing rapidly. There is one Nobel Prize winner in particular whose publications in Tetrahedron Letters (usually a two page paper) are notorious for sacrificing accuracy for rapidity.
In meatspace war, the object was always to damage flesh. We first had blunt objects (stones, clubs) which gave way to sharp piercing weapons (spears, arrows) which gave way to propelled metal (flintlocks, rifles) which gave way to blast waves and shrapnel (shells, bombs) which evolved into directable versions (cruise missiles, armed drones). The next step is probably autocontrolled weapons v1.0, iRobots which scurry through the battlefield and club the enemy or some such.
I wonder where we are on that scale with weaponizable viruses. Are Stuxnet and its peers the equivalent of Predator drones or will we look back decades from now and think that they were the crude matchlock blunderbusses of their day?
Cornyn should shut his fat hypocritic yap. It's his kind that wants to make IP abuse a criminal matter where it should be civil. He's in the crowd who would make violation of TOSs a federal crime. Now he is crying crocodile tears that the Justice Department applied laws he rabidly supported?
Too many damn Reddit users here trying to get imaginary link karma by submitting provocative and incorrect summaries.
That is incorrect. In the classical world, a scandal usually meant the leaders will be executed or murdered, whether it was their fault or not.
You weren't much of a leader if you didn't have a legion of yesmen, buttboys, and fallguys.
It would seem that - with isolated exceptions - having wealth is a get out of responsibility free card. Society generally is more forgiving of the transgressions of the wealthy than of the working class.
This has been the way of the world since... well, forever.
This may be one of the times where we underestimate the ability of the masses to cope with selective information. After all, America's Funniest Home Videos has been on the air for over twenty years and people have adjusted to not having grooms collapse at every wedding and nutsacks being pummeled by every wiffle ball hit.
Indeed. Annoying as hell that they decided to fix one flawed process by instituting another even more flawed process.
If you think about some of the high money contracts it covers, it makes a lot of sense. You want to pave 100 miles of road, you put our specifications for asphalt depth, quality, etc. - all the parameters covering the needed job. Then let all bid on the job. This eliminates somebody's brother in law from getting the contract unless he is the lowest bidder willing to meet the specs.
Where is fails is on the cutting edge of technology. Those potholes on the parkway that appear in the same place every winter and are filled the same way every spring? There are advanced paving methods and materials which could prevent them from forming in the first place but government bidding laws prevent the contract from going to a higher bidder who wants to use experimental technology.
That's because in the US people are trained to always go with the lowest bidder and to only look at the short term return on an investment. My dad was a high-quality remodeler for many years, and it was always a challenge for him to make a customer understand that the guy with the lowest bid was not always the best choice.
Remember that the government "lowest bidder" laws were put into place in response to rampant and blatant contract-fixing. In the private sector, you get what you pay for usually.
"I'm going to be late to the cross burning, my free government blowjob robot broke. farkin' bullshiat man, this guy's the worst president ever. Just like a black guy to give you a blowjob robot for free and it breaks after six years." -Patton Oswalt
I picked up a Windows 8 touch Samsung notebook. Very nice design. When I did this, Windows 8 was no longer the OS I disliked - quite the opposite. Many common things that I used to have to do, (like adjust network settings) were such a chore with the mouse or keyboard. .... Reminds me of when the mouse got real popular.
Nice try. On the second day of astroturf training you will learn to create a real user ID to give you more credibility than just some AC.
Great. Here come the tsunami of middle-aged and elderly users - who were formerly able to rest their wrists on the laptop and type but who now have to lift up their arms to touch the screen constantly - with their complaints as the new interface slowly destroys what was left of their rotator cuffs and shoulder bursas.
I just searched 'shoes'. First three results were on a light violet background marked 'Ads'.
Now who can argue with that? I think we're all indebted to Anonymous Coward for clearly stating what needed to be said. I'm particulary glad that these lovely children were reading Slashdot today to read that speech. Not only was it authentic Internet gibberish, it expressed a courage little seen in this day and age.
I also filed a petition - that I be recognized as the Queen of England. I think mine will be approved just before the one approving DDoSs.
it's always about you, isn't it?
AIG = Ain't I Grateful?
Do the decision makers at Microsoft not have any rotator cuffs? Because just the thought of reaching out to touch a desktop monitor all day makes mine start to ache.
...actually, being a Canadian, I started giving my life story until she told me to shut up.
Something along the lines of this:
"I don’t reckon them times will ever come again. There never was a more bullier old ram than what he was. Grandfather fetched him from Illinois–got him of a man by the name of Yates–Bill Yates–maybe you might have heard of him; his father was a deacon–Baptist–and he was a rustler, too; a man had to get up ruther early to get the start of old Thankful Yates; it was him that put the Greens up to jining teams with my grandfather when he moved west. Seth Green was prob’ly the pick of the flock; he married a Wilkerson–Sarah Wilkerson–good cretur, she was–one of the likeliest heifers that was ever raised in old Stoddard, everybody said that knowed her. She could heft a bar’l of flour as easy as I can flirt a flapjack. And spin? Don’t mention it! Independent? Humph! When Sile Hawkins come a browsing around her, she let him know that for all his tin he couldn’t trot in harness alongside of her. You see, Sile Hawkins was–no, it warn’t Sile Hawkins, after all–it was a galoot by the name of Filkins–I disremember his first name; but he was a stump–come into pra’r meeting drunk, one night, hooraying for Nixon, becuz he thought it was a primary; and old deacon Ferguson up and scooted him through the window and he lit on old Miss Jefferson’s head, poor old filly. She was a good soul–had a glass eye and used to lend it to old Miss Wagner, that hadn’t any, to receive company in; it warn’t big enough, and when Miss Wagner warn’t noticing, it would get twisted around in the socket, and look up, maybe, or out to one side, and every which way, while t’ other one was looking as straight ahead as a spy-glass. Grown people didn’t mind it, but it most always made the children cry, it was so sort of scary. She tried packing it in raw cotton, but it wouldn’t work, somehow–the cotton would get loose and stick out and look so kind of awful that the children couldn’t stand it no way. She was always dropping it out, and turning up her old dead-light on the company empty, and making them oncomfortable, becuz she never could tell when it hopped out, being blind on that side, you see. So...."
The United States of America lost 75% of its Constitutional rights by following this one weird trick!
Personally, I don't think MIT is the "Best" tech college.
You can always tell a nonMIT man.
Previously on Slashdot: Could You Pass Harvard's Entrance Exam From 1869?
Well, would you want a Harvard degree from 1873?
Cam Corvette, charismatic leader
Johnny Pinto, able to burst into flame
Suzy Smartcar, tiny but strong
and of course, The VW Thing
Their next scheme: billboards covered with giant tarps. You have to pay them to unroll the tarp and show you the ad. Brilliant!