I assure you, being in the field and being involved in the patent process, I am much better versed on the topic than you. Thanks for the offer to look around, but I've already done it. A lot. I do it for a living.
There is no grand conspiracy as you would have others believe to keep cures hidden. As I said, NIH does most of the basic research for exploring biology and finding new drugs. Pharm companies do some drug exploration, but the bulk of their research dollars are spent on clinical trials which are *extremely* expensive. Many times there are candidate drugs which don't go on to clinical trials. These are not 'hidden'. Anyone is free to look at the literature to see them. And many researchers I know who have published new exciting results, try to get a story in the more general public news. This gets their name out there, and the Institute/University they work at gets some press that they love. Once again, not hidden. No conspiracy.
Patents are an entirely different issue. Patents are public record. Once again, they aren't hidden from you. Drugs generally have a use patent, so it's easy to see exactly what disease they are for the treatment of. Nothing hidden. Also patents don't last forever. Anyone with a patented drug that works will try to sell it like made for several years, because the patent is going to expire, and then anyone will be able to make a generic version of it, with no patent worries.
If the company patented a drug and sits on it because they don't think they will recoup as much as it would cost to do the trials/manufacturing, well, the patent is still going to expire, so others will be able to use it then. Nothing hidden again. No conspiracy.
Now, if the original company didn't want to go through the expense of doing clinical trials for it because they didn't think they would recoup their money, no one else is likely to want to foot the bill entirely either, since when they get it passed, all their competitors are then free to manufacture generic versions as well.
It all boils down to clinical trials, and who pays for the huge expense of them. No one wants to foot the bill for unpatentable or patent-expired drugs because it's 100+ million down hole for the company doing the trials, and a free ride for all their competitors. It's just terrible business sense. No 'conspiracy' involved at all.
Put away the tinfoil hats. It comes down to simple business decisions a 12-year old should be able to grasp. Blaming pharm companies and academic researchers for 'conspiring' to keep them off the shelf is simply stupid.
If you want a better system for orphan drugs, then lobby your congressmen to expand NIH funding to include drug trials for orphan drugs. Public dollars would be well worth spending in that area.
Take off the tinfoil hat. I'm a medical researcher. If I discover a cure for a disease, I get famous in my field, guaranteed funding, and get invited to speak at research Universities around the world. Maybe even win a Nobel prize. It's all pluses. What do I get to keep it secret if I'm a researcher? Nada.
Uninformed conspiracy nuts seem to think Pharm companies do all the medical research. The NIH (National Institutes of Health) will spend more than 28+ Billion on medical research this year (your tax dollars at work). I do research funded by them. My work is all published in journals you are free to subscribe to, or browse for free at your local research university's library.
The toll 2.5 G would take on the cardio system would not be good. The effects of that are going to be a LOT bigger on the body than you think. Humans survive in 30C to under 0C temps because they can reshape their environment to some extent (put on clothing, build shelter, etc). How are you going to reshape the environment to reduce gravity?
I had the same usage pattern, and trouble with burning most of the ink doing cleaning instead of printing.
I bought an HP 1600 color/network laser. By the end of the of next year I'll be at the break-even point with my inkjet costs. It's great. I'll never buy an inkjet again. And there's a lot more piece of mind knowing that when I next go to print I can just turn on the printer and print, rather than spending 10 minutes doing cleaning passes before something acceptable finally prints out.
I mainly use MSSQL right now, but I've set up the same or helped others set it up similarly for Oracle and PosgreSQL.
I automate the tests with stored procedures which call the test scripts. Yes, everything goes into a subversion repository. I've got a DTS packages set up to move the code for everything to/from a working directory synch'ed with subversion.
Stored procedures are extremely useful for security, to reduce network traffic to the client or application server, to ensure consistency, to take advantage of database-specific features, and most importantly to ensure data integrity.
Easy. The nimrod who wrote the application that you want/need to run didn't make the app database agnostic, so you are stuck with MySQL because "it's more popular". It's a catch 22. Until more folks start writing database agnostic apps, lots of us will get stuck using MySQL in places where we might prefer other databases. And so that will perpetuate MySQL being seen as being more popular... Argh.
And I would fire any moron who refused to use them. There are numerous reasons to use them. I find it scary that anyone employs you as a manager. You must be one of those PHBs from Dilbert.
Probably not, *if* your house jumps over the property line onto my property as the radio waves do. Then it's on my property. Or the same thing might happen onto public property (the street).
Want another analogy since you seem to like them? If you have a fruit tree who's branches extend over the fence to your neighbors property, your neighbors are entitled to keep any fruit that drops on their side of the fence (I won't even discuss their right to make you trim back the tree, which they have in many jurisdictions). That's because it left your property and intruded on theirs, just as your radio waves from your wireless access point to.
Every single wireless router sold these days has encryption built in to it. You simply need to turn it on if you don't want to to share it with people whom YOU ARE BROADCASTING. Once again, if you don't want to share your wireless connection, turn on the encryption, you nimrod.
I call Bullocks on the truck theory. My uncle, as well as numerous local farmers have bee hives that have stayed in the same place for a decade or several decades. The bees have all died off in the last couple years. Something is going on, and it's not trucking.
Many predators, like crocodiles, aren't really what I'd call 'high speed' or big on endurance. They are sneaky, only able to make a quick lunge about the length of their body. If T-Rex was a predator (as opposed to a scavenger), it might not have been (or needed to be) 'fast'.
Agreed; XP is going to be the main OS that software is written for for at least two years (I'm guessing three, but perhaps four), and will be very well supported for at least five years (I'm guessing 7-10)
Your guess would be wrong.
XP came out in 2003. Microsoft has a policy of supporting new OS's for 10 years (their large corporate customers insisted that they keep supporting them that long, and they have contracts in place to enforce it). Full support for 5 years, security support for another 5. We've got a little more than a year before MS stops handing out 'new features' (MS considered the daylight savings time patch to fit in that category). Sometime in 2013, 6 years from now, security support is going bye-bye for XP. Forget about support in 7-10 years. It ain't gonna happen.
It's certainly not perfect, but it reduces the load on my spam-filter. A *lot*. More than 90+% of smtp connections don't make it through spamd here. I hardly call that worthless.
There is no BeOS-based Palm Software. There should have been, but they never released it. It would have been vastly ahead of vanilla PalmOS. BeOS was stable, had multitasking, and make adding/removing software a snap. Ever since BeOS shut down, I've been waiting for Palm to release a PDA with BeOS on it. I'd finally buy one. But it looks like that's never going to happen:(
The official list of exploits for every other OS is also a meaningless metric in that case. Take OpenBSD for example. It's the most secure OS out there (except perhaps for OpenVMS). The OpenBSD folks audit their code, over and over, rewriting messy code that is hard to audit, just in case any nasty bugs are in there but too difficult to weed out. It's the best example you can cite for the open source motto of "many eyes looking over the code finds more bugs" because their eyes are some of the best trained to look for security holes.
It's pretty much a given that they are the most paranoid folks around when it comes to securing their OS (which is why I love it) yet there was a flaw in the memory handling of some IP6 code which left it exposed for years to anyone who might have known about the flaw, but kept it a secret to use themselves. No set of eyes is perfect for finding bugs in software. Every OS you care to mention probably has multiple holes that have been in it for years that might be secretly exploited. So by your reasoning, that standard metric is meaningless for all OS's.
No it's not insane. Lots of customers want full root access on their systems so they can install whatever they want (different database or other servers, or even alternate OS's). Virtualization is the only way to go for that.
Why is it the college's responsibility to make corrections for some random website? Especially one that by it's nature will then let some random 12-year old re-edit the pages with bad information again.
Slashdot Mirror
I assure you, being in the field and being involved in the patent process, I am much better versed on the topic than you. Thanks for the offer to look around, but I've already done it. A lot. I do it for a living.
There is no grand conspiracy as you would have others believe to keep cures hidden. As I said, NIH does most of the basic research for exploring biology and finding new drugs. Pharm companies do some drug exploration, but the bulk of their research dollars are spent on clinical trials which are *extremely* expensive. Many times there are candidate drugs which don't go on to clinical trials. These are not 'hidden'. Anyone is free to look at the literature to see them. And many researchers I know who have published new exciting results, try to get a story in the more general public news. This gets their name out there, and the Institute/University they work at gets some press that they love. Once again, not hidden. No conspiracy.
Patents are an entirely different issue. Patents are public record. Once again, they aren't hidden from you. Drugs generally have a use patent, so it's easy to see exactly what disease they are for the treatment of. Nothing hidden. Also patents don't last forever. Anyone with a patented drug that works will try to sell it like made for several years, because the patent is going to expire, and then anyone will be able to make a generic version of it, with no patent worries.
If the company patented a drug and sits on it because they don't think they will recoup as much as it would cost to do the trials/manufacturing, well, the patent is still going to expire, so others will be able to use it then. Nothing hidden again. No conspiracy.
Now, if the original company didn't want to go through the expense of doing clinical trials for it because they didn't think they would recoup their money, no one else is likely to want to foot the bill entirely either, since when they get it passed, all their competitors are then free to manufacture generic versions as well.
It all boils down to clinical trials, and who pays for the huge expense of them. No one wants to foot the bill for unpatentable or patent-expired drugs because it's 100+ million down hole for the company doing the trials, and a free ride for all their competitors. It's just terrible business sense. No 'conspiracy' involved at all.
Put away the tinfoil hats. It comes down to simple business decisions a 12-year old should be able to grasp. Blaming pharm companies and academic researchers for 'conspiring' to keep them off the shelf is simply stupid.
If you want a better system for orphan drugs, then lobby your congressmen to expand NIH funding to include drug trials for orphan drugs. Public dollars would be well worth spending in that area.
Take off the tinfoil hat. I'm a medical researcher. If I discover a cure for a disease, I get famous in my field, guaranteed funding, and get invited to speak at research Universities around the world. Maybe even win a Nobel prize. It's all pluses. What do I get to keep it secret if I'm a researcher? Nada.
Uninformed conspiracy nuts seem to think Pharm companies do all the medical research. The NIH (National Institutes of Health) will spend more than 28+ Billion on medical research this year (your tax dollars at work). I do research funded by them. My work is all published in journals you are free to subscribe to, or browse for free at your local research university's library.
The toll 2.5 G would take on the cardio system would not be good. The effects of that are going to be a LOT bigger on the body than you think. Humans survive in 30C to under 0C temps because they can reshape their environment to some extent (put on clothing, build shelter, etc). How are you going to reshape the environment to reduce gravity?
It's 5 times the size of earth. I don't think that would make it class M. Finding this one means we might be able to detect them soon though.
I had the same usage pattern, and trouble with burning most of the ink doing cleaning instead of printing.
I bought an HP 1600 color/network laser. By the end of the of next year I'll be at the break-even point with my inkjet costs. It's great. I'll never buy an inkjet again. And there's a lot more piece of mind knowing that when I next go to print I can just turn on the printer and print, rather than spending 10 minutes doing cleaning passes before something acceptable finally prints out.
I mainly use MSSQL right now, but I've set up the same or helped others set it up similarly for Oracle and PosgreSQL.
I automate the tests with stored procedures which call the test scripts. Yes, everything goes into a subversion repository. I've got a DTS packages set up to move the code for everything to/from a working directory synch'ed with subversion.
Not when you realize that most of us got our knowledge of them by playing Morrow Project or video games. ;)
Bull.
Stored procedures are extremely useful for security, to reduce network traffic to the client or application server, to ensure consistency, to take advantage of database-specific features, and most importantly to ensure data integrity.
It is a big assumption. How do you know at no time in the future another application won't be trying to access the database directly?
I write/debug/test/and version control my stored procedures just fine, thank you very much.
Why would you go with MySQL over Firebird?
Easy. The nimrod who wrote the application that you want/need to run didn't make the app database agnostic, so you are stuck with MySQL because "it's more popular". It's a catch 22. Until more folks start writing database agnostic apps, lots of us will get stuck using MySQL in places where we might prefer other databases. And so that will perpetuate MySQL being seen as being more popular... Argh.
And I would fire any moron who refused to use them. There are numerous reasons to use them. I find it scary that anyone employs you as a manager. You must be one of those PHBs from Dilbert.
Probably not, *if* your house jumps over the property line onto my property as the radio waves do. Then it's on my property. Or the same thing might happen onto public property (the street).
Want another analogy since you seem to like them? If you have a fruit tree who's branches extend over the fence to your neighbors property, your neighbors are entitled to keep any fruit that drops on their side of the fence (I won't even discuss their right to make you trim back the tree, which they have in many jurisdictions). That's because it left your property and intruded on theirs, just as your radio waves from your wireless access point to.
Every single wireless router sold these days has encryption built in to it. You simply need to turn it on if you don't want to to share it with people whom YOU ARE BROADCASTING. Once again, if you don't want to share your wireless connection, turn on the encryption, you nimrod.
Please mod parent up. It's the most insightful post I've seen in the entire thread.
FYI, the reports I heard on TV said it was all done with a handgun. I have no idea if those reports are accurate, but that's what was on the TV here.
I call Bullocks on the truck theory. My uncle, as well as numerous local farmers have bee hives that have stayed in the same place for a decade or several decades. The bees have all died off in the last couple years. Something is going on, and it's not trucking.
Many predators, like crocodiles, aren't really what I'd call 'high speed' or big on endurance. They are sneaky, only able to make a quick lunge about the length of their body. If T-Rex was a predator (as opposed to a scavenger), it might not have been (or needed to be) 'fast'.
Mirrors absorb light?
Wow.
And they are hoping to reflect photons (which are light) not electrons.
I think you need to go retake some science classes. Seriously.
Agreed; XP is going to be the main OS that software is written for for at least two years (I'm guessing three, but perhaps four), and will be very well supported for at least five years (I'm guessing 7-10)
Your guess would be wrong.
XP came out in 2003. Microsoft has a policy of supporting new OS's for 10 years (their large corporate customers insisted that they keep supporting them that long, and they have contracts in place to enforce it). Full support for 5 years, security support for another 5. We've got a little more than a year before MS stops handing out 'new features' (MS considered the daylight savings time patch to fit in that category). Sometime in 2013, 6 years from now, security support is going bye-bye for XP. Forget about support in 7-10 years. It ain't gonna happen.
Graylisting is worthless? Umm, no.
1 7105149
It's certainly not perfect, but it reduces the load on my spam-filter. A *lot*. More than 90+% of smtp connections don't make it through spamd here. I hardly call that worthless.
Last year it was more like 99+%. Here's some stats from someone else last year: http://undeadly.org/cgi?action=article&sid=200602
Ahh, thanks for that. I hadn't realized it was actually 'finished' and just that no hardware manufacturer decided to license. it.
I think the reason everyone repeats it is because most folks familiar with BeOS would think it's crazy that no manufacturer would pick it up.
Mod parent up as informative (and sad) please.
There is no BeOS-based Palm Software. There should have been, but they never released it. It would have been vastly ahead of vanilla PalmOS. BeOS was stable, had multitasking, and make adding/removing software a snap. Ever since BeOS shut down, I've been waiting for Palm to release a PDA with BeOS on it. I'd finally buy one. But it looks like that's never going to happen :(
The official list of exploits for every other OS is also a meaningless metric in that case. Take OpenBSD for example. It's the most secure OS out there (except perhaps for OpenVMS). The OpenBSD folks audit their code, over and over, rewriting messy code that is hard to audit, just in case any nasty bugs are in there but too difficult to weed out. It's the best example you can cite for the open source motto of "many eyes looking over the code finds more bugs" because their eyes are some of the best trained to look for security holes.
It's pretty much a given that they are the most paranoid folks around when it comes to securing their OS (which is why I love it) yet there was a flaw in the memory handling of some IP6 code which left it exposed for years to anyone who might have known about the flaw, but kept it a secret to use themselves. No set of eyes is perfect for finding bugs in software. Every OS you care to mention probably has multiple holes that have been in it for years that might be secretly exploited. So by your reasoning, that standard metric is meaningless for all OS's.
No it's not insane. Lots of customers want full root access on their systems so they can install whatever they want (different database or other servers, or even alternate OS's). Virtualization is the only way to go for that.
Why is it the college's responsibility to make corrections for some random website? Especially one that by it's nature will then let some random 12-year old re-edit the pages with bad information again.
I agree entirely. They just aren't funny.
However, Ask A Ninja rocks. I'm glad the awards got that one right at least.