Plus the ones like Vioxx and Celebrex that make it through but may actually cost the companies money due to lawsuits. One has only to look at the stock chart for Merck to see what losing one drug will do to the value of the company.
I'm sure that's true; they seemed to be siphoning off the whole "buffy coat" which is the area between red cells and plasma. The machine processed 5 times my total blood volume and only reduced WBC from like 28 down to 23, so they must lose a lot of separation efficiency in order to run the continuous process. I didn't want them to batch-process my entire blood supply:)
Neupogen IS the drug used to increase WBC, but apparently it also increases stem cell count in the marrow to the degree that stem cells escape into the peripheral blood.
The docs told me they were stem cells and googling neupgen stem cell transplant yields similar stories, for example:
http://www.flex.com.au/~kaye/Patexp.html
As my brother's bone marrow is going to be destroyed by chemotherapy, I hope they know what they are talking about.
The BIG mystery to me is how the machine works without twisting up the lines. There are 4 tubes connected to the main centrifuge tube; everything is plastic and discardable, but the main centrifuge tube spins. I can see how one would connect one line up with a spin decoupler, but more than one would have to get twisted as far as I can see. Maybe they are nested with multiple spin decouplers.
I did a stem cell donation for my brother last week. It cost about $6000 and involved hooking up veins in both arms to a continuous centrifuge that pumped blood out of one arm, centrifuged it to remove the stem cells, and then injected the plasma and red cells back into the other arm. I had to get injections of Neupogen for four days prior to what the docs called the "harvest". I didn't have to have long needles stuck into my bone marrow. The worst part was not being able to move my arms for 5 1/2 hours for any reason because of the needles in veins in my elbows.
They got 3 times as much material as they need and I am trying to arrange to have the rest stockpiled in case I need them at some later date. They needed 8 million cells per kilo of body weight for a cross donation, but only 4 million for self-donation.
At least you got a straight answer; those form letters are usually constructed by staffers to avoid committing the pol on anything while pretending to agree with the writer.
Denmark has dealt with Stalin living next door; they are not scared of Microsoft. If it comes down to it, they can cost Bill a lot more than he can cost them -- a nice open-source mandate would be a good place to start.
This is from a talk at the Gartner Group. Adaptive technology seems to be about lending empowerment to the shifting paradigm of the value proposition:
"You have to think about your enterprise horizontally, not vertically, because every process is going to become digital, mobile, virtual. Once you start to think about your business horizontally, there is a set of processes supported by infrastructure. The goal is to have that be simpler, easier to manage, more reliable and more adaptable," Fiorina said.
"We're talking about helping customers instrument infrastructure, applications and processes so they can manage them with service-level agreements. You have to take complexity out. You have to simplify, standardize, virtualize and integrate," she described.
All the hype around the movement toward utility computing or on-demand computing or the adaptive enterprise has created confusion in the IT world. Fiorina took a stab at providing a more crisp definition of HP's adaptive enterprise initiative, describing it as an end state.
"The end state we're talking about is a business where every business decision can be supported by the underlying process, application and technology in way that's real time. The business and IT are linked and flexible," she said.
According to Fiorina, adaptive enterprise requires thinking about the enterprise not as a set of independent, standalone islands of automation, but as a set of processes, applications and underlying technologies.
"We think adaptability can be measured across time and range and ease. By time mean when you make a business decision, how long does it take to reflect that change? If you change a price, how long does it take to reflect that in the underlying system? This is an era where how things work together is everything," she said.
"Then there's ease--how hard is it to do those things? You can measure it. Finally adaptive enterprise is a framework that describes our products, services, software, standards and partners."
"Lastly adaptive enterprise isn't rocket science and it is not a Star Trek mystery: it says customers can create a more adaptive enterprise by doing some fundamental (but hard) things. Simplify, standardize, virtualize and integrate processes, applications and infrastructure," she concluded.
Last week there was a new store opened up in Tucson called "Printer Cartridge World" or some such. They specialize in refilling ink cartridges. This could be bad news for HP's razor-blade pricing model. Even better (or worse if you're HP) would be a mail-order refiller, postage-paid both ways, boxes supplied, etc, like Netflix or Seattle Film Works. Does anybody do this?
It comes from two factors: First, Bill spends more time in front of cameras than any other founder of a fortune 500 company. I don't know many of the others -- Michael Eisner at Disney, Andy Grove at Intel. Second, the company he personifies so assiduously is well known to be one of the most rapacious, thieving, lying monopolies in history.
You can pretty much expect self-serving lies from any head of a major corporation; if they told the truth their stockholders might sue them. Same goes for politicians, lawyers, etc, really these people have nothing interesting to say. Reading them makes one stupider, not smarter; it's all dis-information.
If one is making an iso-fruitopic comparison one also needs to remember that the costs of a repair mission are probably pretty accurate (they've done a few already) while the costs of building a new scope and launching it are wild-ass guesses.
So which engineer at Microsoft figured out how to break their API so that Lotus Notes wouldn't run but Microsoft products would? Someone should write the history of that also.
You also can expense the cost immediately rather than having to write it off over 7-10 years. Unless you've gotten smarter (acquired intellectual capital) in which case you have to appraise and declare that, too!
Hiring engineers away from Borland for 300K salaries and then putting them on extended vacations (but under no-compete contracts so they couldn't go back to Borland)? I'm just guessing here.
I tried to install a Suse system and it wanted to reformat the entire drive. I couldn't get it to install on my existing partitions. Tried Gentoo and it compiled for 3 days (literally) and then failed. Redhat's init.d turns the sky overhead black with crisscrossing symlinks.
I just love Slackware -- it's so straightforward and unpretentious. Doesn't hide the boot or installation processes behind GUI's.
Slashdot Mirror
10 watts per square foot is typical, 120 watts per square inch is a ludicrous claim.
I look forward to hearing from Shirley Maclaine and Moammar Khaddafi, two original thinkers who can move their lips without lying, on this issue.
See this for some more contemporary measurements.
What happens when the speed of light changes?.
Plus the ones like Vioxx and Celebrex that make it through but may actually cost the companies money due to lawsuits. One has only to look at the stock chart for Merck to see what losing one drug will do to the value of the company.
c kc hart.asp?symb=mrk&sid=0&o_symb=mrk&x=0&y=0
http://bigcharts.marketwatch.com/quickchart/qui
I'm sure that's true; they seemed to be siphoning off the whole "buffy coat" which is the area between red cells and plasma. The machine processed 5 times my total blood volume and only reduced WBC from like 28 down to 23, so they must lose a lot of separation efficiency in order to run the continuous process. I didn't want them to batch-process my entire blood supply :)
My favorite are the standard Java comments like // Public instance methods
// Private static methods.
in front of all the public instance methods.
etc.
I've seen way too much Java code where those are the only comments in the file.
Neupogen IS the drug used to increase WBC, but
apparently it also increases stem cell count in the marrow to the degree that stem cells escape into the peripheral blood.
The docs told me they were stem cells and googling
neupgen stem cell transplant yields similar stories, for example:
http://www.flex.com.au/~kaye/Patexp.html
As my brother's bone marrow is going to be destroyed by chemotherapy, I hope they know what they are talking about.
The BIG mystery to me is how the machine works without twisting up the lines. There are 4 tubes connected to the main centrifuge tube; everything is plastic and discardable, but the main centrifuge tube spins. I can see how one would connect one line up with a spin decoupler, but more than one would have to get twisted as far as I can see. Maybe they are nested with multiple spin decouplers.
I did a stem cell donation for my brother last week. It cost about $6000 and involved hooking up veins in both arms to a continuous centrifuge that pumped blood out of one arm, centrifuged it to remove the stem cells, and then injected the plasma and red cells back into the other arm. I had to get injections of Neupogen for four days prior to what the docs called the "harvest".
I didn't have to have long needles stuck into my bone marrow. The worst part was not being able to move my arms for 5 1/2 hours for any reason because of the needles in veins in my elbows.
They got 3 times as much material as they need and I am trying to arrange to have the rest stockpiled in case I need them at some later date. They needed 8 million cells per kilo of body weight for a cross donation, but only 4 million for self-donation.
Yeah, that'll work :) although it would be better to just use them as feedstock.
The nice thing about this is that it puts a cap of around $80/barrel on oil, at least till we run out of turkey guts and poop.
At least you got a straight answer; those form letters are usually constructed by staffers to avoid committing the pol on anything while pretending to agree with the writer.
Denmark has dealt with Stalin living next door;
they are not scared of Microsoft.
If it comes down to it, they can cost Bill a lot more than he can cost them -- a nice open-source mandate would be a good place to start.
This is from a talk at the Gartner Group.
Adaptive technology seems to be about lending empowerment to the shifting paradigm of the value proposition:
"You have to think about your enterprise horizontally, not vertically, because every process is going to become digital, mobile, virtual. Once you start to think about your business horizontally, there is a set of processes supported by infrastructure. The goal is to have that be simpler, easier to manage, more reliable and more adaptable," Fiorina said.
"We're talking about helping customers instrument infrastructure, applications and processes so they can manage them with service-level agreements. You have to take complexity out. You have to simplify, standardize, virtualize and integrate," she described.
All the hype around the movement toward utility computing or on-demand computing or the adaptive enterprise has created confusion in the IT world. Fiorina took a stab at providing a more crisp definition of HP's adaptive enterprise initiative, describing it as an end state.
"The end state we're talking about is a business where every business decision can be supported by the underlying process, application and technology in way that's real time. The business and IT are linked and flexible," she said.
According to Fiorina, adaptive enterprise requires thinking about the enterprise not as a set of independent, standalone islands of automation, but as a set of processes, applications and underlying technologies.
"We think adaptability can be measured across time and range and ease. By time mean when you make a business decision, how long does it take to reflect that change? If you change a price, how long does it take to reflect that in the underlying system? This is an era where how things work together is everything," she said.
"Then there's ease--how hard is it to do those things? You can measure it. Finally adaptive enterprise is a framework that describes our products, services, software, standards and partners."
"Lastly adaptive enterprise isn't rocket science and it is not a Star Trek mystery: it says customers can create a more adaptive enterprise by doing some fundamental (but hard) things. Simplify, standardize, virtualize and integrate processes, applications and infrastructure," she concluded.
Last week there was a new store opened up
in Tucson called "Printer Cartridge World"
or some such. They specialize in refilling
ink cartridges. This could be bad news for
HP's razor-blade pricing model. Even better
(or worse if you're HP) would be a mail-order
refiller, postage-paid both ways, boxes
supplied, etc, like Netflix or Seattle Film
Works. Does anybody do this?
Google has this word indexed today and this
page is the only entry. We'll see what happens
next
It comes from two factors: First, Bill spends more time in front of cameras than any other founder of a fortune 500 company. I don't know many of the others -- Michael Eisner at Disney, Andy Grove at Intel. Second, the company he personifies so assiduously is well known to be one of the most rapacious, thieving, lying monopolies in history.
You can pretty much expect self-serving lies
from any head of a major corporation; if they
told the truth their stockholders might sue
them. Same goes for politicians, lawyers, etc,
really these people have nothing interesting to
say. Reading them makes one stupider, not
smarter; it's all dis-information.
If one is making an iso-fruitopic comparison one also needs to remember that the costs of a repair mission are probably pretty accurate (they've done a few already) while the costs of building a new scope and launching it are wild-ass guesses.
There is a very thorough and reasonably up-to-date
m tc -00028565b.htm
account of M$'s piratical practices at:
http://www.usdoj.gov/atr/cases/ms_tuncom/major/
It looks to be an amicus brief prepared by
Consumer's Union.
So which engineer at Microsoft figured out how to break their API so that Lotus Notes wouldn't run but Microsoft products would? Someone should write the history of that also.
You also can expense the cost immediately rather than having to write it off over 7-10 years.
Unless you've gotten smarter (acquired intellectual capital) in which case you have to appraise and declare that, too!
I can remember blowing $200 per minute on the Univac 1108 at Georgia Tech, when my program got into an infinite loop.
Hiring engineers away from Borland for 300K salaries and then putting them on extended vacations (but under no-compete contracts so they couldn't go back to Borland)? I'm just guessing here.
Microsoft apparently thought Google was good enough, as MS tried to buy Google. What they cannot acquire they will destroy.
I tried to install a Suse system and it wanted to reformat the entire drive. I couldn't get it to install on my existing partitions. Tried Gentoo and it compiled for 3 days (literally) and then failed.
Redhat's init.d turns the sky overhead black with crisscrossing symlinks.
I just love Slackware -- it's so straightforward and unpretentious. Doesn't hide the boot or installation processes behind GUI's.