+ 5 - If Slashdot had stickies, this would be up top on Biology / Molecular Biology articles. Tape this to your monitors, folks.
(Except as a caveat, even Nature / Science / PNAS and Cell have blown it big time on occasion. Nothing is certain. Eat dessert first. Do Not Taunt Happy Fun Ball.)
Mitochondria are thought to be a (relatively late) Major Event - the genetic and biosynthetic pathways were already fairly advanced.
The major idea behind a LUCA is that you can 'work the clock back' with DNA sequencing to something around 4 billion years ago AND that all life-as-we-know-it relies on a fairly specific set of chemical reactions. It's pretty clear that modern organisms are a mismash of A+C+B+x - nature hates to throw genetic material away. It's also perfectly reasonable to assume that life started / stopped multiple times and that bits of earlier life were indeed incorporated into later critters. When you start talking about that, you get into some terribly annoying semantic arguments (perfect for Slashdot).
The Holy Grail would evidence of organisms using wildly different chemistry (like incorporating arsenic into the DNA backbone instead of Phosphorus) or some molecule that transferred genetic information without DNA or RNA entirely.
This is one strong reason why we should get our respective asses towards Mars. It offers the closest laboratory for finding off-world life. What that looks like (if it exists) is going to be one of the biggest scientific discoveries ever.
So, for life on earth, it's pretty clear that there is one LUCA - something started us along the pathway to RNA and DNA based life (I'm personally a proponent of RNA World). And TFA implies that that this enzyme was present fairly early on. But something further back had to set the stage for the ability of an organism to fold amino acids into proteins, etc. TFA doesn't even begin to discuss what the chemistry would have been - that''s another story - but by the time Thioredox was on the scene, something was making RNA and there was something that looked like a ribosome - pretty advanced functions. How they got there is pretty much hand waving.
Hospitals should not be required to provide free health care to anyone who walks in with a sniffle. Hospitals should be required to provide health care to those with serious injuries or other life-threatening situations.
We don't provide free health care for everyone with a sniffle. We triage patients. If it is deemed not to be an emergency (note that this is a rather bizarre legal definition, not a medical one), they get sent out with a nice little piece of paper that suggests they see someone in a clinic.
The sniffles and coughs don't crowd the ERs - it's the actually fairly sick people who can't get care anywhere else. Including the illegal immigrants.
And if you think ERs want to figure out immigration status on people, you should check into the psych ward along with the rest of the politicos.
I have a relative who works in the health industry and by far the biggest leeches on the free hospital care are people who come in with colds or related afflictions (flu), those looking to score a hit and yes, illegal immigrants.
Utter bullshit. People with colds and sniffles don't take much time, even if we see them (see above). Pill seekers are a bit more annoying, but they don't take a whole lot of resources in general. The things that cost money are the folks we do CTs and expensive tests on, and even more so, the folks that we admit and run more expensive tests on. If you want to save a bunch of money, outlaw (and somehow effectively manage the ban) on alcohol, and to a lesser degree, tobacco. Those nice legal drugs cost society a metric shitload of money.
How do you refine the lead and avoid fumes from smelting? Do you use a low temp process?
Do you have a bunch of OSHA / EPA regs you need to follow? Curious, because battery manufactures have to go through all sorts of hoops to work with lead plates.
Once a towel gets wet, it starts to smell funny. Apocalyptic survivors want to smell fresh and clean.
WD-40 for the wilderness isn't that much use, for the most part you will want more friction not less.
Speak for yourself, brother... You're forgetting the 1000s of other uses - fire starter, mosquito repellent, zombie repellant, bear repellant. The list goes on and on. Just because you're in the wilderness, doesn't mean that you can just ignore civilization.
Duct tape, has a limited use time until your roll runs out.
Again, such a failure of imagination. You can build a house, a dress, a condom (well, that might be a stretch). Fix a car / boat / airplane / bicycle. Splint a fracture, cover a wound.
A knife you can use over and over again, sharpen it on a stone and keep going. You can strip bark and make rope, which can allow you to tie the knife at the end of a stick to make a deadly spear. You can scrape it against some flint to start a fire.
Well, yes, of course. But if you just have a little knife and I've got a can of WD 40, then I'm going to spray you in the face, grab your knife and make some sparks.
That isn't entirely correct. One of the big issues I have with Mr. Adams is that he totally ignored WD40 and Duct tape. I don't care if he thinks he knows the answer to everything, your travel bag is not complete without those two essentials.
Not really. People kayak around them all of the time. If they were particularly aggressive, we would know about it. Sea Lions are more obnoxious. Not that I would go out and try and pet one, but I've been within 50 yards of them before. It does get the heart going - the could crunch the kayak or small boat and find the chewy nugget inside but they don't seem to care one way or the other.
Slashdot Mirror
The greatest shortcoming of the human race is our inability to understand the exponential function.
Albert Bartlett
Samuel Johnson.
That'll be 25 cents. PayPal accepted. No bitcoins.
It's not a duplicate.
It's a backup copy. Can't be too paranoid these days.
"Men rarely (if ever) manage to dream up a god superior to themselves. Most gods have the manners and morals of a spoiled child. "
Heinlein
+ 5 - If Slashdot had stickies, this would be up top on Biology / Molecular Biology articles. Tape this to your monitors, folks.
(Except as a caveat, even Nature / Science / PNAS and Cell have blown it big time on occasion. Nothing is certain. Eat dessert first. Do Not Taunt Happy Fun Ball.)
Mitochondria are thought to be a (relatively late) Major Event - the genetic and biosynthetic pathways were already fairly advanced.
The major idea behind a LUCA is that you can 'work the clock back' with DNA sequencing to something around 4 billion years ago AND that all life-as-we-know-it relies on a fairly specific set of chemical reactions. It's pretty clear that modern organisms are a mismash of A+C+B+x - nature hates to throw genetic material away. It's also perfectly reasonable to assume that life started / stopped multiple times and that bits of earlier life were indeed incorporated into later critters. When you start talking about that, you get into some terribly annoying semantic arguments (perfect for Slashdot).
The Holy Grail would evidence of organisms using wildly different chemistry (like incorporating arsenic into the DNA backbone instead of Phosphorus) or some molecule that transferred genetic information without DNA or RNA entirely.
This is one strong reason why we should get our respective asses towards Mars. It offers the closest laboratory for finding off-world life. What that looks like (if it exists) is going to be one of the biggest scientific discoveries ever.
So, for life on earth, it's pretty clear that there is one LUCA - something started us along the pathway to RNA and DNA based life (I'm personally a proponent of RNA World). And TFA implies that that this enzyme was present fairly early on. But something further back had to set the stage for the ability of an organism to fold amino acids into proteins, etc. TFA doesn't even begin to discuss what the chemistry would have been - that''s another story - but by the time Thioredox was on the scene, something was making RNA and there was something that looked like a ribosome - pretty advanced functions. How they got there is pretty much hand waving.
What about the sex part?
Hospitals should not be required to provide free health care to anyone who walks in with a sniffle. Hospitals should be required to provide health care to those with serious injuries or other life-threatening situations.
We don't provide free health care for everyone with a sniffle. We triage patients. If it is deemed not to be an emergency (note that this is a rather bizarre legal definition, not a medical one), they get sent out with a nice little piece of paper that suggests they see someone in a clinic.
The sniffles and coughs don't crowd the ERs - it's the actually fairly sick people who can't get care anywhere else. Including the illegal immigrants.
And if you think ERs want to figure out immigration status on people, you should check into the psych ward along with the rest of the politicos.
I have a relative who works in the health industry and by far the biggest leeches on the free hospital care are people who come in with colds or related afflictions (flu), those looking to score a hit and yes, illegal immigrants.
Utter bullshit. People with colds and sniffles don't take much time, even if we see them (see above). Pill seekers are a bit more annoying, but they don't take a whole lot of resources in general. The things that cost money are the folks we do CTs and expensive tests on, and even more so, the folks that we admit and run more expensive tests on. If you want to save a bunch of money, outlaw (and somehow effectively manage the ban) on alcohol, and to a lesser degree, tobacco. Those nice legal drugs cost society a metric shitload of money.
Man, Dropbox better watch out. Serious competition here.
But really, had the NSA pitched their product as a 'service', people would have fallen all over themselves to pay for it.
"Stores everything, everywhere! Never back up again!"
What's not to like?
(A)bort, (R)etry, (F)ail.
That's because you're a cat. Dogs wag and bark and smile.
And chew on mobile phones.
How do you refine the lead and avoid fumes from smelting? Do you use a low temp process?
Do you have a bunch of OSHA / EPA regs you need to follow? Curious, because battery manufactures have to go through all sorts of hoops to work with lead plates.
Buckshot. That said, I'm not sure how many people actually use that for deer hunting.
That's much too subtle for this audience.
A lot of people who fly fixed wing planes really don't consider helicopters as 'aircraft'.
"Helicopters do not fly. The ground repels them because they are so ugly."
You press that big button on the top (not shown in the picture) and the flight deck folds up and guns pop out.
Sheesh. Haven't you seen the Transformers movie yet?
Spelling counts
Punctuation, not so much.
It's French! How do you think it got this outrageous accent?
For the most part a towel is more handy.
Once a towel gets wet, it starts to smell funny. Apocalyptic survivors want to smell fresh and clean.
WD-40 for the wilderness isn't that much use, for the most part you will want more friction not less.
Speak for yourself, brother... You're forgetting the 1000s of other uses - fire starter, mosquito repellent, zombie repellant, bear repellant. The list goes on and on. Just because you're in the wilderness, doesn't mean that you can just ignore civilization.
Duct tape, has a limited use time until your roll runs out.
Again, such a failure of imagination. You can build a house, a dress, a condom (well, that might be a stretch). Fix a car / boat / airplane / bicycle. Splint a fracture, cover a wound.
A knife you can use over and over again, sharpen it on a stone and keep going.
You can strip bark and make rope, which can allow you to tie the knife at the end of a stick to make a deadly spear. You can scrape it against some flint to start a fire.
Well, yes, of course. But if you just have a little knife and I've got a can of WD 40, then I'm going to spray you in the face, grab your knife and make some sparks.
Kids these days.
And none of these can be created with a 3D printer. What is wrong with these people?
All one needs is a towel.
That isn't entirely correct. One of the big issues I have with Mr. Adams is that he totally ignored WD40 and Duct tape. I don't care if he thinks he knows the answer to everything, your travel bag is not complete without those two essentials.
Just view it at your convenience.
One of them did manage to get a highly acclaimed documentary about their inevitable demise. Good ol Timothy Treadwell aka 'the Kodiak snack'.
Not really. People kayak around them all of the time. If they were particularly aggressive, we would know about it. Sea Lions are more obnoxious. Not that I would go out and try and pet one, but I've been within 50 yards of them before. It does get the heart going - the could crunch the kayak or small boat and find the chewy nugget inside but they don't seem to care one way or the other.
"Any users accessing a Freedom Hosting hosted site since 8/2 with javascript enabled are potentially compromised."
That would include all the FBI computers used to deliver the poison, then?
Nah, they're probably using IE 6. Still.