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User: RollinDutchMasters

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Comments · 15

  1. Re:Do it in China. on Publicly Funded GMO Research Facing Destruction In Italy · · Score: 1

    Italy isn't exactly an R&D powerhouse. They're a science third-world country. The places where GMO research is being aggressively pursued are only becoming more active as the underlying biology improves. Some of that is in China, yes, but the bulk is in the major research centers in the US, Canada, and Germany.

    Ultimately, GMO agriculture is essential to the long-term stability of our civilization as global warming starts to push on food production. Some disorganized and largely ignorant resistance isn't going to stop a nickel of research grant money in these countries from going out.

  2. Re:$1000 on The Race To $1,000 Human Genome Sequencing · · Score: 2

    You're missing the point. You don't need a thousand-dollar test to tell you what color your hair is. You do need a thousand dollar test to tell you how your specific cancer is disregulated, and which pathways which have been damaged can be targeted by non-cytotoxic chemotherapy drugs. That's the true revolution behind cheap sequencing; it tells you EXACTLY what the problem is. This means you can move from drugs that kill everything, hoping that they kill cancer faster, to drugs that inactivate or inhibit very specific things which are only present in the cancer. That is the revolution. That's what we need sequencing for.

  3. Re:Designer Humans? on The Race To $1,000 Human Genome Sequencing · · Score: 1

    This isn't true at all. Human somatic cell nuclear transfer (SCNT) cloning doesn't work. We don't know why. It partially works (you get early development) if you bootstrap by leaving a partial copy of the oocyte genome in the recipient cell, but that's not developmentally viable past a certain point. There's absolutely a difference for humans and we don't know what it is. Until we do, we can't do human cloning.

  4. Re:Rosalind Franklin on Double-Helix Model of DNA Paper Published 59 Years Ago · · Score: 1

    Rosalind Franklin has credit. Her paper is published in the same issue of Nature as the Watson and Crick paper, it's two pages away. She'd have shared the Nobel prize if she hadn't died before it was awarded. She got a bit screwed, but she's hardly the first academic you can say that about.

  5. Re:No way on Biotech Company Making Fossil Fuels With a 'Library' of Bacteria · · Score: 4, Informative

    The Joule technology requires no "feedstock," no corn, no wood, no garbage, no algae. Aside from hungry, gene-altered micro-organisms, it requires only carbon dioxide and sunshine to manufacture crude. And water: whether fresh, brackish or salt.

    How can anyone with a high school chemistry education take this bullshit seriously?

    People with a high school biology education know that CO2 + H20 + Sunlight = Sugar, thanks to the magic of photosynthesis and the Calvin Cycle. Sugar + anaerobic respiration = Ethanol, thanks to the magic of anaerobic ethanol fermentation. You can argue that their bioreactors will need nutrient supplementation to maintain viability, and you'd be right. Those are not feedstocks however, as you only need small amounts relative to product. It's not bullshit, it's science.

  6. Re:Obvious and boring on Are 68 Molecules Enough To Understand Diseases? · · Score: 2, Informative

    It's interesting in that this is a nice summary of information that we've known for a while that has never been presented in so succinct a format.

    I had a table with that molecular breakdown in my biochem textbook. It was just black&white instead of colored, and it didn't look like it was made in Illustrator.

    Way to go to him for... coloring... I guess. It's still pretty 1970-y information.

  7. So..... on Are 68 Molecules Enough To Understand Diseases? · · Score: 3, Insightful

    He's just discovered something that's in every first-year biochemistry textbook that's been published for the last 30 years?

    I love when 'cutting-edge research' is actually old information with a pretty new graph/picture/powerpoint slide/animation/etc.

  8. Fantastic on Black Screens For Unauthorized Copies of Windows · · Score: 2, Insightful

    Given that there are a number of pieces of malware which break WGA and cause it to fail to validate (most of which are not trivial to clean out), why exactly would Microsoft have WGA punish them even more? I'd have to imagine that people with actual pirated copies of windows will just continue to not visit windowsupdate and continue to not have the WGA. I don't see this having a major effect on anyone except legitimate users.

  9. Re:Softball on Your Lord of the Rings Online Questions Answered · · Score: 1
    It was completely worth the softball questions to give someone from Turbine a chance to call Blizzard unoriginal. While it's true, it still makes my irony-meter explode just because of who said it.

    Quick, with LOTRO out the door, they've run out of popular licenses to butcher - someone sell them Firefly!

  10. Re:The company should be able to do this... on Eve Online to Elect Player Oversight Group · · Score: 1
    There already are strong internal controls, but the people who insist on nailing themselves to the cross to protest a lack of INTERNET JUSTICE simply refuse to believe anything released by an internal audit. More amusing are the denials that they even exist because if they existed then CCP would be trustworthy but I don't trust CCP so they dont exist because if they existed then CCP would be trustworthy... its a merry-go-round of people martyring themselves over perceived injustices in an internet spaceship game.

    The biggest mistake CCP made was releasing a game where you can actually defeat people in a meaningful way - a minor mistake by a GM in WoW creates a stupid post on a blizzard forum already drowned in an avalanche of idiocy. In EVE, the same thing makes slashdot with people decrying the lack of internal controls.

  11. Re:Whoa. on Eve Online to Elect Player Oversight Group · · Score: 1
    It's not going to set any precedent - it's an outrageously stupid idea. It does absolutely nothing, because the people who are crazy enough to believe in the existing tinfoil-hattery menagerie of half-truths and no-truths about corruption can easily extend that same insanity to whoever is doing 'oversight'.

    CCP is screwing themselves by even giving legitimacy to the entire thing. In the end, it will just be one more group which can be complained about - with only 9 winners, the 90% of the population which doesn't back one of them will feel marginalized and out of the loop because of it. Plus, since its an internet popularity contest, all 9 of those people will be retards.

    Just about the only thing this is good for is a bit of publicity from the same news outlets that seem to have a creepy obsession with Second Life (We're going to put a virtual ABC studio between the virtual kiddie-raping theme park and the virtual bestiality bazaar!) Its like the mainstream news outlets are daring MMOGs to one-up each other in insane concepts which will make a fancy headline and 3 sentences of text. At some point, the circus is just going to fall apart.

  12. Re:Bad PR move: Never whine on EVE Online Scandal Deliberate Frame-Job? · · Score: 1
    Right now, CCP has three clients - normal, GM, and Dev. You can't use a Dev or GM client without being at CCP's offices, you cant use a Dev or GM client with a non-Dev or non-GM character. Even the developers play their normal characters with the normal client, which has no access to any of the devtools.

    Not that this has stopped anyone from assuming otherwise for no reason at all.

  13. Re:Actually, it's not that hard a concept on EVE Online Scandal Deliberate Frame-Job? · · Score: 1
    If you define "fair" as being the ability to achieve anything in a game regardless of your interaction with other players, then EVE isn't fair and wasn't meant to be. Fair as you've defined it is simply not exciting. That's not the problem though - it's a game where the work of hundreds of people can be invalidated and destroyed by hundreds of other people working harder. That's what both attracts the kind of people who like to win, and makes them go completely batshit insane.

    Genuinely losing at a videogame is not something that many people are capable of handling. The losing party in EVE almost always puts the blame squarely on something which was not their fault - that's been the case for years. Its only in the last year and a half that CCP has been drawn into that kind of petty mudslinging.

    Honestly, I think that the people responsible for oversight at CCP have just become so aggravated by all the bile hurled at them whenever someone in the game feels wronged in some way by someone else that they've lost the ability to play deft PR. I can't say I blame them.

  14. It Shouldn't Suprise Anyone on EVE Online Scandal Deliberate Frame-Job? · · Score: 5, Insightful

    EVE is one of the few MMOGs where other players can legitimately destroy huge amounts of your hard work, if you've dared to step into the alliance warfare arena. People don't like to be beaten, it's far easier to accept that you've lost if you have something to pin it on. Traditional targets have been incompetent allies, the vague 'internal problems', people leaving EVE for other games (Lineage II was popular with the old Forsaken Empire - too popular), essentially anything which can deflect blame. The odd 'CCP is helping my enemies cheat' accusation cropped up, but that was relatively uncommon - up until about a year ago, that is. Since then, everything is a result of someone, anyone, with authority tilting the scales in favor of the other guy. If you're winning, its because someone is cheating for you. It's both incredibly sad and completely unsurprising that the human response to losing at even trivial games is to bitch and moan - a problem which is compounded on the internet, because you can make up whatever you want and noone will ever have the ability to tell you to stop being an ass. At least in organized sports, the "Fucking Refs" phenomenon only works for a limited time, until someone slaps the hell out of you and tells you to stop being an idiot.

  15. Re:The Significance of Cheating in EVE on EVE Devs Admit To Misconduct · · Score: 1

    Significant Cheating... I'm getting sick of people claiming that what was given to BoB was significant in any way. A handful of BPOs, most of which were of limited value - in the context of alliance economics at that scale, it was nothing. A few days of complex running for BoB's collection of 10/10s at most. The reason that this is an issue is that any help whatsoever was given to one alliance by a rogue developer - NOT that the help which was given was non-trivial. Now its just degenerated into a bunch of idiots rabble-rousing for political gain and a herd of sheep following along.