Well, I agree that one of my first thoughts was that glycine is the simplest amino acid and therefore not quite as exciting as finding one or more of the other amino acids. However, it's important to remember that the important characteristic of amino acids is their ability to polymerize via condensation reaction of the amino group of one with the carboxyl group of another. The only thing that distinguishes glycine from the other amino acids (except for proline) is that it "only" has a H for its R group. All it takes is substitution of a methyl group at that position and suddenly you have alanine, one of the most abundant amino acids found in proteins.
5) the gel got contaminated on earth. or the mass spec is not definitive about the molecule in question.
I lean towards 5, and then 3 as a close second.
I would have agreed with you before I RTFA. The authors acknowledged contamination as a confounding factor, and tested for it by isotopic analysis of the C13:C12 ratio, where glycine from space is expected to have a greater amount of C13. This is precisely what they found, allowing them to conclude that the glycine did, in fact, come from the comet.
Well...fruit flies have been shown to be capable of learning by classical conditioning. Some may not consider this to be true pain, but they will avoid an odor that has been previously paired with an electric shock.
I believe you intended to refer to BRCA1 and BRCA2
you don't want this info getting to insurance companies
I could've sworn I saw a story here not too long ago about federal legislation banning insurance companies from discriminating against people on the basis of genetic testing. However, this factsheet from the National Cancer Institute indicates otherwise. If possible, it would seem testing yourself anonymously would indeed be prudent.
No way in hell anyone who hasn't had massive experience with PCR is going to get results from a DIY PCR...PCR protocols, although simple, are incredibly touchy and take a lot of time to get consistent results from.
I have to disagree with you here, at least for checking a specific, limited set of loci. IAAMB (molecular biologist) but I don't have "massive" experience with PCR and yet I've never had trouble getting it to work by following standard protocols using quality reagents (e.g. from NEB) and primers (from IDT). As long as the DIY guide included directions to use IDT's software to assist them in choosing primers and to determine the annealing temperature to use during the PCR cycle, I don't see why your typical DIYer with access to some old lab equipment wouldn't be able to get it to work as long as the DNA prep was good.
I would imagine a limiting factor to this approach would be the cost of the necessary equipment, with thermocyclers running in the thousands of dollars.
Or you could NOT be a fucking retard and just use CSV.
Right, because there's no way they would possibly want to include anything other than a single table of raw data in their reports, such as charts, or data organized across multiple sheets.
I can't find it now after a couple quick searches, but I believe somebody actually tried this, resulting in a temporary boost of his FAH "team" into the lead in work units processed. There was a sizable outcry within the folding community when people realized what he had done, due to the potentially damaging effect on the project if FAH were to be associated with computer viruses.
The summary claims that the monkeys learned to correctly "put up to 18 photos...in a row." However, TFA states that the two rhesus macaques "learned to place five photographs in a particular order" and that "In all, each monkey learned to order at least 18 separate series of photographs". I won't make any claims as to which task is easier, but I wanted to clear up that particular point for those few who skip straight to the comments.
One theory of autism that has received a fair amount of attention in the past few years is that autistic spectrum disorders may result from mirror neuron dysfunction. The mirror neuron system is thought to allow humans (and some primates) to mentally simulate the actions of others, thereby allowing greater understanding of their intentions and motivations. Preliminary results (PDF) indicate that this system may be impaired in individuals with ASD, resulting in characteristic social deficits as the result of inability to internally simulate observed actions.
Calvin: I like to verb words. Hobbes: What? Calvin: I take nouns and adjectives and use them as verbs. Remember when "access" was a thing? Now, it's something you do. It got verbed. Verbing weirds language. Hobbes: Maybe we can eventually make language a complete impediment to understanding.
One fewer move: 1. f3 e4 2. g4 Qh4++ shit!
Well, I agree that one of my first thoughts was that glycine is the simplest amino acid and therefore not quite as exciting as finding one or more of the other amino acids. However, it's important to remember that the important characteristic of amino acids is their ability to polymerize via condensation reaction of the amino group of one with the carboxyl group of another. The only thing that distinguishes glycine from the other amino acids (except for proline) is that it "only" has a H for its R group. All it takes is substitution of a methyl group at that position and suddenly you have alanine, one of the most abundant amino acids found in proteins.
5) the gel got contaminated on earth. or the mass spec is not definitive about the molecule in question.
I lean towards 5, and then 3 as a close second.
I would have agreed with you before I RTFA. The authors acknowledged contamination as a confounding factor, and tested for it by isotopic analysis of the C13:C12 ratio, where glycine from space is expected to have a greater amount of C13. This is precisely what they found, allowing them to conclude that the glycine did, in fact, come from the comet.
Well...fruit flies have been shown to be capable of learning by classical conditioning. Some may not consider this to be true pain, but they will avoid an odor that has been previously paired with an electric shock.
This kind of language abuse makes my head literally explode!
George Bush criticiz nafta for spotted owl gay sex with firearms
blam!
brac gene (breast cancer)
I believe you intended to refer to BRCA1 and BRCA2
you don't want this info getting to insurance companies
I could've sworn I saw a story here not too long ago about federal legislation banning insurance companies from discriminating against people on the basis of genetic testing. However, this factsheet from the National Cancer Institute indicates otherwise. If possible, it would seem testing yourself anonymously would indeed be prudent.
No way in hell anyone who hasn't had massive experience with PCR is going to get results from a DIY PCR...PCR protocols, although simple, are incredibly touchy and take a lot of time to get consistent results from.
I have to disagree with you here, at least for checking a specific, limited set of loci. IAAMB (molecular biologist) but I don't have "massive" experience with PCR and yet I've never had trouble getting it to work by following standard protocols using quality reagents (e.g. from NEB) and primers (from IDT). As long as the DIY guide included directions to use IDT's software to assist them in choosing primers and to determine the annealing temperature to use during the PCR cycle, I don't see why your typical DIYer with access to some old lab equipment wouldn't be able to get it to work as long as the DNA prep was good.
I would imagine a limiting factor to this approach would be the cost of the necessary equipment, with thermocyclers running in the thousands of dollars.
Or you could NOT be a fucking retard and just use CSV.
Right, because there's no way they would possibly want to include anything other than a single table of raw data in their reports, such as charts, or data organized across multiple sheets.
Same link as parent, but clickable: http://www.galaxyzooblog.org/2008/03/20/voorwerp-fever/
I believe you misplaced your exclamation point.
Of course, if your current wireless plan is already $49.99, the math becomes:
8GB iPhone $199 + $10 * 24 = $439
I can't find it now after a couple quick searches, but I believe somebody actually tried this, resulting in a temporary boost of his FAH "team" into the lead in work units processed. There was a sizable outcry within the folding community when people realized what he had done, due to the potentially damaging effect on the project if FAH were to be associated with computer viruses.
The summary claims that the monkeys learned to correctly "put up to 18 photos...in a row." However, TFA states that the two rhesus macaques "learned to place five photographs in a particular order" and that "In all, each monkey learned to order at least 18 separate series of photographs". I won't make any claims as to which task is easier, but I wanted to clear up that particular point for those few who skip straight to the comments.
One theory of autism that has received a fair amount of attention in the past few years is that autistic spectrum disorders may result from mirror neuron dysfunction. The mirror neuron system is thought to allow humans (and some primates) to mentally simulate the actions of others, thereby allowing greater understanding of their intentions and motivations. Preliminary results (PDF) indicate that this system may be impaired in individuals with ASD, resulting in characteristic social deficits as the result of inability to internally simulate observed actions.
Calvin: I like to verb words.
Hobbes: What?
Calvin: I take nouns and adjectives and use them as verbs. Remember when "access" was a thing? Now, it's something you do. It got verbed. Verbing weirds language.
Hobbes: Maybe we can eventually make language a complete impediment to understanding.