Slashdot Mirror


Stem Cell "Master Gene" Found

nexex writes "From the Washington Post, 'Scientists yesterday said they have discovered a long-sought "master gene" in embryonic stem cells that is largely responsible for giving those cells their unique regenerative and therapeutic potential.' The report summarizes an article in the newest issue of the scientific journal, Cell."

230 comments

  1. Potential by Limburgher · · Score: 5, Insightful

    Since they've now apparently isolated this gene, isn't it kind of like having "root" access to stem cells? Hopefully this kills off any remaining debate over cloning/killing babies and paves the way for real, theraputic research.

    --

    You are not the customer.

    1. Re:Potential by Turing+Machine · · Score: 5, Insightful

      They still need to learn how to turn it on.

      As I understand it (and I'm not even an amateur in this field, so take this for what it's worth) that's one of the major problems facing genetic scientists. There are many, many cases where they know which gene is responsible for something, but they don't yet know how how that gene is switched on (or off).

      I guess it's like knowing the root password, but not having a shell or any other way of making use of it. :-)

    2. Re:Potential by Pinguu · · Score: 3, Funny

      isn't it kind of like having "root" access to stem cells?
      What's the stem cells IP? I'm gonna hax0r it ^^

      --
      --
    3. Re:Potential by pe1rxq · · Score: 5, Insightful

      No, more like knowing the account is named 'root' but not having the password.

      Jeroen

      --
      Secure messaging: http://quickmsg.vreeken.net/
    4. Re:Potential by stoborrobots · · Score: 4, Informative
      One opportunity to kill off this debate is listed in this New Scientist article someone else posted...

      He says a more immediate use of the key gene would be to enable the medical profession to grow "millions and billions" of ESCs from existing samples. These could then more safely be used in humans, as they would not have been exposed to the "cocktail" of chemicals currently needed.

    5. Re:Potential by s88 · · Score: 3, Insightful

      "I guess it's like knowing the root password, but not having a shell or any other way of making use of it. :-) "

      Isn't it more like knowing that root is the account you want, but not knowing the password?

      Scott

    6. Re:Potential by BWJones · · Score: 4, Informative

      Since they've now apparently isolated this gene, isn't it kind of like having "root" access to stem cells?

      Not quite. Because you know which gene is responsible does not mean you know how to 1) activate it, 2) turn it off, 3) modulate it's activity. All three of these possibilities will be different in various tissues that may have differing rates of turnover. Take for instance lung tissue versus neural tissue. Lung tissue turns over quite a bit from stem cell populations, whereas neural tissue does not (well mostly does not).

      The whole genomics world is just the beginning in that there will be a whole post-genomics world where scientists need to figure out how all of the code works. We just now are getting to the point where we know what the code is and its general order, but we do not know how all of it works. It's like reverse engineering a system where we are not certain of all of the rules by which the system is constructed. With computer code at least, one can know the general order of code, its structure and execution. Bioscience is more......slippery. :-)

      --
      Visit Jonesblog and say hello.
    7. Re:Potential by moz711 · · Score: 2, Insightful

      Why bother figuring out how it's turned on? Just engineer a transgene, with the gene and a promoter sequence that you do know how to control (there are many different types, and some can be manipulated by external chemical control). Then insert the transgene into a test cell and use the added promoter sequence to turn it on at will.

    8. Re:Potential by Anonymous Coward · · Score: 0

      hehehehheh. He said "cock"

    9. Re:Potential by jalet · · Score: 0, Offtopic

      > No, more like knowing the account is named 'root'
      > but not having the password.

      At the LILO prompt, they just have to pass some additionnal arguments to bypass to launch of the init command :

      LILO: linux init=/bin/bash

      They don't need to know the root password.

      Well, maybe LILO is protected by a password too...

      --
      Votez ecolo : Chiez dans l'urne !
    10. Re:Potential by Anonymous Coward · · Score: 1, Funny

      Maybe unix metaphores isn't the best way describing stem cell resaearch?

    11. Re:Potential by Anonymous Coward · · Score: 0

      I clicked on the site, and got this:

      The following COMException has been caught

      eslo.core.jni.COMException: 0x80004005 E_FAIL [FACILITY_NULL "Unspecified error "] (Get records failed. talkProtocol.store_cards() failed with errorstate 2.)
      ------------
      and a lot of additional code...

    12. Re:Potential by nounderscores · · Score: 2, Insightful

      Good idea. And you could put in an antisense version with a promoter to turn off the natural copy at will.

    13. Re:Potential by the+uNF+cola · · Score: 2, Funny

      One gene to rule them all, and in darkness bind them? /frodo

      --

      --
      "I'm not bright. Big words confuse me. But Wanda loves me and that should be enough for you." - Cosmo

    14. Re:Potential by Anonymous Coward · · Score: 1, Funny
      They still need to learn how to turn it on.

      You'd think with all the P0rn on the internet they could find something that would turn it on.

    15. Re:Potential by Anonymous Coward · · Score: 0

      +1 Don't Know what the hell they're talking about but it sounds techie to me.

    16. Re:Potential by Cipster · · Score: 2, Interesting

      The problem with that is that you would have to continuously control the gene externally (essentially try and baby sit it). It would be much more easy to figure out how to turn an upstream switch on since:
      -You get to take advantage of cellular signal amplification so you will only need a small initial signal to turn on the cascade.
      -You can take advantage of the regulatory system apready in place so the newly activated cells don't turn into a tumor or worse.

    17. Re:Potential by junkgrep · · Score: 1

      Embryonic stem cell research WAS real theraputic research.

    18. Re:Potential by OhioJoe · · Score: 1

      Well, when you see a tractor pulling a load up a hill, and it is gaining speed, you're likely to believe it is going to crest the hill. That is what is going on with stem cell research. They keep learning more and more, and just when you think it will be another 10 years before the next big find, whamo, they've hit another big find.

      And for the record, there are few if ANY stem cell researches (SCR) who wish to work on "embryo's", unless you say blastocyst's are embryo's. And if you do, than 1 out of 4 females' body discards an embryo in further stages of development than what SCR scientists are working with, and she doesn't even know it. SCR scientists want Invitro Fertilzation Clinic 'blastocysts' that are being discared due to 'non prime specimen' reasons. In other words, SCR scientists want to intercept the blastocysts on their way to the dumpster. Where are all the picket signs outside of IVR clinics?

      --
      "Artificial Intelligence usually beats real stupidity."
    19. Re:Potential by rugwuk · · Score: 1

      - You can take advantage of the regulatory system apready in place so the newly activated cells don't turn into a tumor or worse.
      Whats worse than a tumor cell?

      --
      Its one damn thing before another. (Dick Bird 1999)
    20. Re:Potential by MrPotatoeHead · · Score: 1

      Good idea. And you could put in an antisense version with a promoter to turn off the natural copy at will.

      why does everyone always want to experiment on will?

      *groan* :)

    21. Re:Potential by the+uNF+cola · · Score: 1
      They still need to learn how to turn it on.


      A little dinner.. a little wine.. a little atmosphere..

      Too easy :)
      --

      --
      "I'm not bright. Big words confuse me. But Wanda loves me and that should be enough for you." - Cosmo

    22. Re:Potential by Anonymous Coward · · Score: 0

      My (poor) understanding of the genome project.

      Is it not parallel to having 'discovered' all the notes Beethoven used in his symphonies?

      Will scientists now tell us that all we have to do is find a way to crank out world-changing symphonies for only 93 cents each?

    23. Re:Potential by Cipster · · Score: 1

      A teratoma. It's very hard to treat since technically it's normal tissue in an abnormal place. So you end up with teeth or hair growing in someone's lungs.

    24. Re:Potential by nycsubway · · Score: 1

      I think it's more like knowing the base class from which all other classes are derived. like CObject in Microsoft Foundation Classes.

  2. Is this patentable? by dtolton · · Score: 5, Interesting

    Something you have to wonder is if they are going to patent this
    information? I would hope that since this is being done at a
    University that won't happen. Although with all the recent patent
    craziness, I wouldn't be completely suprised if they granted a patent
    on it.

    It still concerns and dismays me greatly that there is any discussion
    of patenting things like the human genome. As many have said, they
    are a discovery rather than an invention. Let's hope this research
    follows that philosophy.

    Sadly, the fact that stem cells have great potential application to
    ease human suffering is seen by many people as a great way to make a
    buck. It's even worse that most of this research is funded by our
    tax dollars, then we have to turn right back around and pay a high
    per item cost to help defray research costs. ::sigh::

    --

    Doug Tolton

    "The destruction of a value which is, will not bring value to that which isn't." -John Galt
    1. Re:Is this patentable? by EmagGeek · · Score: 5, Funny

      The human genome has already been patented. Patent number 00000001 is owned by God, and was issued a few million years ago. But, I don't think he's capable of enforcing it as there are no lawyers in heaven.

    2. Re:Is this patentable? by dissy · · Score: 3, Insightful

      > Something you have to wonder is if they are going to patent this
      > information

      Thats the nice thing about being a University, they dont need to patent, they just publish.
      Why pay for a patent if its suppost to be open? When you publish, you can always prove prior art to any future patents a jerk would try to make to steal the technology. And thats all that needs to be protected if it is to be open and public knowledge.

      I just hope having it open instead of using it to make huge profits is exactly what they have on their minds.

    3. Re:Is this patentable? by the+gnat · · Score: 5, Insightful

      I would hope that since this is being done at a
      University that won't happen.


      So would I, but bitter experience has proved that this expectation is unreasonable. A number of the existing stem cell lines that have been annointed as available to federally-funded researchers are in fact patented by the University of Wisconsin, if memory serves. However, perhaps the fact that this latest discovery was made in Scotland and Japan will change things.

      It's even worse that most of this research is funded by our tax dollars, then we have to turn right back around and pay a high per item cost to help defray research costs.

      I hear this a lot on Slashdot, but it misses half of the point. The problem is with patents on basic research, which do not represent a marketable product. A gene patent is commercially useless without extensive further research, e.g. traditional drug development. In contrast, many patents held by academic groups are for inventions that have immediate commercial potential. For instance, the automatic DNA sequencer was invented at Caltech, presumably with federal grant money, then patented. It was immediately commercialized, enabling a high-quality product to get to market quickly. (It was also truly revolutionary at the time.) Gene patents, on the other hand, are usually just used to stifle further research by competitors who might actually be capable of realizing its medical and economic potential.

      (This is distinct from junk patents that hardly meet any of the other standards such as novelty and non-obviousness. I've also seen a fair number of those applied for by academic groups. I think this reflects the sad fact that competition has become so much more intense that scientific ethics have increasingly disappeared - this is not limited to patents. Since I'd prefer to keep my job, I can't go into as much details as I'd like.)

    4. Re:Is this patentable? by maxpublic · · Score: 4, Insightful

      Patenting existing genes is unconstitutional in any event. As is clearly stated, both patents and copyrights exist to allow *inventors* and *artists* to profit from their work for a brief period of time, before that work must be released into the public domain.

      Discovered natural events, like genes, are not 'invented'. There is no constitutional basis for issuing a patent for a discovery of this nature. You could patent the *invention* used to isolate and manipulate the gene, but patenting the gene itself is bogus, a ridiculous extension of the process that goes well beyond constitutional protections.

      Unless, of course, the people involved in trying to patent the gene suffer from the delusion that they are god.

      Max

      --
      My god carries a hammer. Your god died nailed to a tree. Any questions?
    5. Re:Is this patentable? by Jugalator · · Score: 0, Redundant

      No, but Hell is full of them. :-)

      --
      Beware: In C++, your friends can see your privates!
    6. Re:Is this patentable? by VanillaCoke420 · · Score: 1

      You can't patent information. Especially not since it's been around everywhere all the time. You can't even copyright it.

    7. Re:Is this patentable? by Anonymous Coward · · Score: 0
      Patenting existing genes is unconstitutional in any event.

      Not to mention how outrageously illogical and wrong it is.

    8. Re:Is this patentable? by the+gnat · · Score: 3, Interesting

      I agree, but unfortunately it's not really 'unconstitutional" until the Supremes say so (or until Congress passes a law, which wouldn't make it unconstitutional but would have the same effect). What's needed is for a gene patent to stifle medical research on some high-profile illness, particularly an illness that afflicts some group with lots of money and political clout. Only people realize the damage that gene patents can do, there will be considerable motivation to steamroll over the whining of biotechs and patent lawyers and declare them illegal. I'm a little surprised that Myriad's BRCA1 patent hasn't done this here, though Canada and France seem to be slowly getting the message.

      (Again, this is different from, say, AIDS drug patents, which I'd argue are still necessary even though Big Pharma needs to chill the fuck out. People would be far more outraged if a gene patent was used to block the sale of a live-saving drug, though I'm not sure how this is any different from Myriad suing breast-cancer researchers. Call it the difference between greed and spite.)

    9. Re:Is this patentable? by SUB7IME · · Score: 1

      In my Bioethics class at Yale I was informed that, in order to be patentable, the information coding a gene cannot be natural.

      For instance, if I manually create a new gene that exists nowhere in nature (as far as we know) then I am free to patent that, but if I merely discover a gene that already exists, I may not patent it.

      I will say nothing, though, about the patenting of techniques, which I will leave to abler minds.

    10. Re:Is this patentable? by roskakori · · Score: 4, Funny
      The human genome has already been patented. Patent number 00000001 is owned by God
      no, you are mistaken. although patent number 00000001 is owned by god, it refers to "light".
    11. Re:Is this patentable? by OldFart58 · · Score: 1

      Umm... no. Wasn't that patent number 0? In an orderly universe, IMHO, counting starts at zero ;-)

    12. Re:Is this patentable? by skywire · · Score: 2, Interesting

      You have the right idea about patents in general. However, a few years ago Congress decided to let discoverers of genes patent them. This is certainly a legal oddity (conflicting with the core meaning of patents in US law), but they wanted to encourage such discovery, and the patent system was a practical tool for effecting the policy.

      --
      Those who would give up essential liberty to purchase a little temporary safety, deserve neither liberty nor safety.
    13. Re:Is this patentable? by Anonymous Coward · · Score: 0

      Violators just get sent to the lawyers...

    14. Re:Is this patentable? by Anonymous Coward · · Score: 0

      Hello? Mr. Obvious called for you, and he wants his post back.

    15. Re:Is this patentable? by rulethirty · · Score: 0

      So is patent 000000000 for God?

    16. Re:Is this patentable? by saldek · · Score: 1

      Who needs lawyers when you have lightning bolts?

    17. Re:Is this patentable? by Courageous · · Score: 1

      When you publish, you can always prove prior art...
      ----
      Once someone else gets a patent, it takes about $10 million in legal fees to invalidate it, even if there exists prior art. That's why a lot of companies these days patent dubious things; they feel that a patent in their hands is a legal defense tactic against someone *else's* predatory moves.

      C//

    18. Re:Is this patentable? by Anonymous Coward · · Score: 0

      Erm, Universities still want patents. It's a good way for them to make money and protect their IP at the same time.

    19. Re:Is this patentable? by thomasmd · · Score: 1

      How would you suggest that research be funded, if not by the american people? The reason we are the most dominant country in the world scientifically is because we devote so much money to research. If we want to continue leading the world in scientific advances (and hence healthcare advances) we need to continue the funding through taxes. It simply is not possible to conduct the amount of research that is performed in the United States using private money. As far as the issue of patents -- all universities have scientific patent offices now, so don't be surprised if they try and patent this somehow.

  3. LIES ALL LIES!!!!! by Anonymous Coward · · Score: 4, Funny

    This GOVERNMENT filth is misinformation!

    Support BABY HARVESTING. It's the only way for a brighter future! Kill cancer, HARVEST BABIES!

    1. Re:LIES ALL LIES!!!!! by Anonymous Coward · · Score: 0

      In Soviet Russia, cancer harvests you.

    2. Re:LIES ALL LIES!!!!! by cruppel · · Score: 1

      Now now now, we don't want to be harvesting babies...the machines will do that in due time, after we scorch the sky.

    3. Re:LIES ALL LIES!!!!! by utexaspunk · · Score: 1

      yes, everyone knows the cure for cancer is baby oil... ba-dum-bum...

  4. Does this mean no more embrionic research? by SpamJunkie · · Score: 5, Interesting

    Can anyone familiar with the details say if this will end the need to do research on embryos? This seems to be a controversial aspect of stem cell research and eliminating this need may help win public acceptance.

    1. Re:Does this mean no more embrionic research? by stoborrobots · · Score: 3, Informative

      The article suggests that in the near term, this will actually boost the need for research on embryos, to figure out how this "nanog" stuff works...

      However, it does mean that (hopefully) down the track, those things which can now only be cured with embryonic transplants will be curable with alternative techniques...

      Happy to answer any other queries on the subject (have been following the subject *VERY* closely for a few years now... Also working in bioinformatics this month...)

    2. Re:Does this mean no more embrionic research? by nfk · · Score: 5, Informative

      They answer that in the article:

      "THE DISCOVERY of the gene brings scientists closer to a holy grail of biology: the ability to turn ordinary cells into those that possess all the biomedical potency of human embryonic stem cells, eliminating the need to destroy embryos to get them.

      Researchers cautioned that the new work (...) will not bring a quick end to the political controversy over human embryo research."

      They even say that it might intensify research on embryos, for now.

    3. Re:Does this mean no more embrionic research? by dbrutus · · Score: 1

      Actually, I am not aware of any actual embryonic stem cell treatments that are in clinical use. The hope has been high but hasn't panned out yet. The supposedly less capable adult stem cell therapies *are* out there and curing people without all the moral difficulties embryo therapies present.

      Could you give a ref. to an actual embryonic treatment that is in actual use?

    4. Re:Does this mean no more embrionic research? by littleRedFriend · · Score: 1

      The basic research has been done and will be done on mouse embryos.

      The discovery will hopefully lead to a cell line (originated from only a couple of human embryos, a single time) that can be growed indefinitely and without using chemicals to keep the cells from differentiating.

      So yes, there would be no more need for human embryos for "production" of stem cells and it would probably be safer and more reproducible for the patients as well.

      --
      IANAL, but imagine a beowulf cluster of in Soviet Russia all your belong are base to us welcoming the new SCO overlords.
    5. Re:Does this mean no more embrionic research? by stoborrobots · · Score: 4, Informative
      You're right (or at least to my knowledge) from a clinical perspective... There are no clinical-grade or even advanced research-grade treatments available... I didn't stress the "plausible but not proven" sense of the word "can" in my last post. My bad...

      However, I seem to recall some successes in among the spectacular failures... The only thing I can turn up seems to be this rather cryptic link (scan down to point 3) which alludes to the successes I (think I) can remember... It was a while ago though, before I was following this... So my memory may be unclear, or I may be hyping this more than it deserves... I will be back in touch if I find a more concrete reference...

      Also, there has been considerably less research on the embryonic stemcells than the adult variants, because of the moral difficulties, which may partly explain why there are more successes with the latter...

    6. Re:Does this mean no more embrionic research? by iawia · · Score: 1

      The way I read the article, the whole point is that there will be no need to harvest stem cells from embryo's once they find out how the NanOg gene is activated at about the 4th day of pregnancy.

      Once that is known, it will be possible to 'trigger' an adult cell to transform into a pluripotent cell.

      The whole system of using just a couple of cell lines is only usefull for research (and that limit has been an obstacle for research as well), not for medical application of stem cells.
      The point of using stem cells being that you could use cells with your own DNA to create new tissue/organs instead of donor material.

    7. Re:Does this mean no more embrionic research? by stoborrobots · · Score: 1
      There's this reference to successful treatment of under-60y.o. Parkinson's patients... The experiment was not a resounding success, but the treatment worked.

      I'm not sure if this is the one I am thinking of, but the timing is about right...

    8. Re:Does this mean no more embrionic research? by stoborrobots · · Score: 1
      And it may have had resounding failure later ...

      I may have to withdraw my previous statement... Not just yet, I still have a little confidence in my memory, but I may have to...

    9. Re:Does this mean no more embrionic research? by dbrutus · · Score: 1

      I can smell the snake oil from here. Low life expectency patients (read desperate), techniques that have not, apparently been peer reviewed and demonstrated efficacious, this sounds suspiciously like shamanism which, if they're just injecting saline and calling them fetal cells, I don't have much of a problem but if they're actually using the cells to gain advantage of the placebo effect...

  5. Unacceptable research? by stoborrobots · · Score: 5, Insightful

    If they have found the controller for the unlimited reproduction abilities of these cells, then we may be well on the way to curing many of these harmful diseases... True cures for Alzheimers and Parkinsons???

    maybe even eliminate costly transplants...

    Who knows, we could even save Michael J Fox's career... =)

    Hopefully the people in charge realise that this is more than an attempt "to transcend embryo research ... [because] it's wrong".

    1. Re:Unacceptable research? by Anonymous Coward · · Score: 0

      Who knows, we could even save Michael J Fox's career... =)

      I'm all for that, but hopefully they will save his life and he can decide whether he still wants to work, y'know?

      I met him once - very cool guy.

    2. Re:Unacceptable research? by Zanth_ · · Score: 3, Funny

      Who knows, we could even save Michael J Fox's career... =)

      Or even save Michael Jackson's face!

      Er...its pretty far gone, maybe not.

    3. Re:Unacceptable research? by Anonymous Coward · · Score: 0

      Back to the Future 4: Mr. Fusion powered hoverboards!!!

    4. Re:Unacceptable research? by jmccay · · Score: 1

      I know I will takea karma hit for saying this, but so be it because what I have to say is true. It applies to all those who suuport this type of research. What's next? Testing chemicals and bio-warfare on mentally disabled people?
      I bet that's what the Nazi's thought when they started to run all those tests on Jewish prisioners. You sound just like them. You want a cure at what cost? I have an aunt with Parkinsons who would love to be cured, and I have a man who was like a grandfather to me die of Alzheimers. I have seen what Alzheimers does and what Parkinsons does in it's later stages. I am sure that both of these people would not want a cure that was discovered/created by using body parts of dead babies sold and traded as commodities.
      Did you know a whol industry has grown out of selling fetuses? Their are companies who one traffic in human body parts produced from abortions.
      Did you know that if a baby manages to survive an abortion (like a saline abortion) that the doctor or a nurse will STRANGLE the living child till it is dead? Did you know there are times when the nurse, or doctor, oculdn't do this and they took the baby to be adopted? These are both true facts!
      DO you know what happens in a partial birth abortion? The woman is induced to start labor, and before the baby's head comes out into the real world, the baby is killed.
      Do you know that younger babies are just scrapped out of the womb? Did you know this could cause infertility becuase the woman might not be able to sustain a fetus.
      You people who support/do this type of reseach are no better than the Nazi's when the experiment on the Jewish prisoners they had in the concentration camps. The Japanesee weren't much better to their prisoners.

      --
      At the next eco-hypocrisy-meeting, count the private jets used to get to the meeting. Should be interesting to see that
    5. Re:Unacceptable research? by Anonymous Coward · · Score: 0
      "I am sure that both of these people would not want a cure that was discovered/created by using body parts of dead babies sold and traded as commodities."

      Hey it's like any dead animal in africa, you better put it to good use by letting those Lions and it's cubs to eat it. Would you let that tastey meat go to waste, hell no! So, better make use of dead babies rather than flush em down toilets, and burying them, talk about pointless.

      "Did you know that if a baby manages to survive an abortion (like a saline abortion) that the doctor or a nurse will STRANGLE the living child till it is dead? Did you know there are times when the nurse, or doctor, oculdn't do this and they took the baby to be adopted? These are both true facts!"

      Boy, you better have proof of that, I'm not buying that for a second.

    6. Re:Unacceptable research? by Anonymous Coward · · Score: 0

      You can ask the nurses who have done it. This just goes to show how ignorant you reall are about this subject.

    7. Re:Unacceptable research? by jmccay · · Score: 1

      I will probably take a karma hit for offering proof, but so be it. It'll be worth it if even just one abortionist changes their views ( or one innocent unborn child is saved).
      Here is proof of survivors. This woman is now 24, but when she was 19 she testified before congress about her situation. She is an abortion survivor. Her mother chose to abort her, but she survived!

      You tell me how that is this humane? You liberal and feminist assholes keep talking like a baby is a clump of cells, but this woman is proof that they are not just a clump of cell.
      Pro-choice vegans are no better (especially PETA). They cry fowl about the inhumane teatment of animals, but it perfectly fine to kill a baby that's being born (partial birth abortion). See this link (fox is slow today) for a VERY BASIC description of what partial birth abortion. The way the abortion bill is phrased is what happens when a doctor performs a partial birth abortion. How are these things humane? Tell me this, and don't answer with the "it's a womans right to choose" crap because that's an excuse (and avoids the REAL QUESTION)!!!!
      Here are some more links (1 and 2) to read if you have the guts to read them! There is more is you care to look, and it is very hard to find a written story that confirms that the doctors (or nurses) will kill a baby after it's born if it survives the abortion attempt--usually by strangling. If you anything on it, it's form the point of view that it's a womans right.

      --
      At the next eco-hypocrisy-meeting, count the private jets used to get to the meeting. Should be interesting to see that
    8. Re:Unacceptable research? by shaitand · · Score: 1

      let's not get too carried away here.

    9. Re:Unacceptable research? by shaitand · · Score: 1

      I'm Pro human experimentation, baby or otherwise. One or a million human life are nothing when compared to the foundation of knowledge of humanity for all time. People die, information generally does not.

      You won't convince me or anyone else.

    10. Re:Unacceptable research? by jmccay · · Score: 1

      I supposed you have no problems with the torturous test the Nazis performed on the Jews in WWII? What about the test the Japanesee performed in WWII? What about you? How about we start testing things on you, and then we can throw you away like a used napkin!

      --
      At the next eco-hypocrisy-meeting, count the private jets used to get to the meeting. Should be interesting to see that
    11. Re:Unacceptable research? by shaitand · · Score: 1

      No problem with any of that, the strongest should survive and no individual takes priority over the species as a whole. Individuals live a lil while, then they die, new ones spout up, then they die too, as individuals they don't matter in the greater scheme, all that matters is the contributions they leave behind, these test subjects left great contributions.

      Well I do have problems with some of the experimentation done, this isn't something that should be done for experimentation sake, only when it actually is for the purpose of increasing knowledge and has a good potential to benefit those that come after.

  6. can you turn Master gene on/off? by 192939495969798999 · · Score: 4, Funny

    What happens if you turn the Master gene on for a normal cell, or off in the stem cell? Does that automatically make the cell grow into a baby? That would be wild!

    --
    stuff |
    1. Re:can you turn Master gene on/off? by Baumi · · Score: 5, Informative

      Stem cells don't automatically grow into babies - if that were the case, this'd be the Easy Route to human cloning.

      An in-depth look into what stem cells are, can be found here.

    2. Re:can you turn Master gene on/off? by Anonymous Coward · · Score: 0

      the Easy Route to human cloning

      and then you could clock the time it takes them to publish "cloning for dummys" and "cloning for idiots" with an egg timer

    3. Re:can you turn Master gene on/off? by thasmudyan · · Score: 1

      No, but the question is interesting. I wonder if a gene therapy that activates this gene leads to incredibly increased cancer risk (beyond the risk already associated with gene therapy of course) because setting the STEM_CELL flag might also deactivate growth and replication controls?
      If so, would this mean that in order to repair/regrow tissue we whould probably do it offline (in a growth tank or something) and then insert the ready grown and thus stem-cell-free tissue into the body of a patient?
      Any biologists out there to provide some insight?
      (Sorry, if that was already answered in the article but there has been a slashdotting, in case you wouldn't have guessed.)

    4. Re:can you turn Master gene on/off? by Anonymous Coward · · Score: 1, Funny

      How about "spelling for dummies?"

    5. Re:can you turn Master gene on/off? by Monkey-Man2000 · · Score: 1

      This reminds of the South Park episode with the nurse and the dead fetus in her head. Of course, it would be interesting to be able to clone myself using just the shit I scratch off my head.

      --
      This post was generated by a Cadre of Uber Monkeys for Monkey-Man2000 (603495).
    6. Re:can you turn Master gene on/off? by diaphanous · · Score: 3, Informative

      I'm not very knowledgeable about stem cells, but I read the Chambers et al. paper (but not Mitsui et al.), and I think I understand the main points and if I'm wrong hopefully someone more knowledgeable will correct me.

      Mouse embryonic stem cells use a couple of factors- gp130 signalling, Oct4, and Nanog to retain their state as stem cells. Chambers et al. showed that that raising the levels of Nanog allows embryonic stem cells to maintain their "stemness"- their undifferentiated state- in the abscence of gp130 signalling. If you remove nanog, then whether the embryonic cells remained stem cells or became more specialized would probably depend on the levels of gp130 signalling, although it seems that nanog may be the limiting factor.


      ~Phillip

    7. Re:can you turn Master gene on/off? by teslatug · · Score: 2, Funny

      You must make sure you've also set the jumper correctly or you could leave it on CS

    8. Re:can you turn Master gene on/off? by juhaz · · Score: 1

      Not a biologist, but if stemm cells would all turn to cancer, no human would ever have born (remember the religious debate of harvesting stem cells from embryos?) human, but a chaotic lump of cancerous tissue.

    9. Re:can you turn Master gene on/off? by thasmudyan · · Score: 1

      if stemm cells would all turn to cancer, no human would ever have born

      Of course - but, you see, cancer is (to use a computer analogy) when the cellular system crashes in a very bad way. A cell basically just starts replicating and replicating, killing the host organism in the process. Now, that can only happen if the growth inhibitor "sub-systems" of a cell get damaged. Because a cell has to function as part of a whole organism, and because getting out of control is potentially fatal, there are very many reduntant controlling subsystems that handle inter-cellular communication, so the collective organism can achieve the common goal (=keeping this whole bunch of cells alive long enough to reproduce). This is a very delicate, though redundantly secured, system that basically tells the cell when to reproduce, and what chemistry to perform.
      Inserting genes into "the running program" and switching them around, puts this delicate genetic program in severe danger. That's because when we alter or (de)activate genes in gene therapy, we basically insert new code into the cell's running program (cool, imagine that)!
      Part of the problem is, that our code-insertion process is so crude, it ends up inserting code not only at the desired places but all over the system. Most of the chaos resulting from that is straightened out be the cell's error correction mechanisms, but it is sufficient to largely increase the cancer risk for gene therapy patients.
      Those undifferentiated stem cells reproduce very actively, they are not designed to be present in a fully grown organism like that. All sorts of things could go wrong. In addition to that, considering the extensive genetic manipulation needed to revert it to stem cell mode, as well as the fact that we completely lack the knowledge about what to do with this state of extreme programmability a stem cell is in, it seems probable that a large number of those cells end up either dead or cancerous.
      But I'm no biologist either, just thoughts from a programmers perspective...

  7. Washington Post? by Sygnus · · Score: 0, Offtopic
    Looks more like msnbc.com to me. Looks like the submitter needs to RTFA himself.

    --
    First posting isn't trolling. It's...first posting. :) -- Illiad
    1. Re:Washington Post? by Anonymous Coward · · Score: 1

      WashingtonPost.com Highlights
      Ability to manipulate 'master gene' may aid therapy
      By Rick Weiss
      THE WASHINGTON POST

      Don't tell someone to RTFA when you haven't read the fucking article.

    2. Re:Washington Post? by dbrutus · · Score: 1, Flamebait

      MSNBC says the story comes from the Washington Post. MSNBC is full of reprints from other sources.

      Maybe you need to RTFA more carefully.

  8. This is also on Newscientist.com by azav · · Score: 5, Informative

    And was posted on May 30 Link follows: Here

    --
    - Zav - Imagine a Beowulf cluster of insensitive clods...
  9. Re:Yes!!! lets get relion fanatics out of medicine by dbrutus · · Score: 0, Flamebait

    Watch out what you ask for. If you get those religious/moral types too far out of science you end up with Mengele reruns throwing jews into freezing water just to measure how quickly they die. It's good science but morally impermissible.

  10. Foreskin restoration!? by Martin+Marvinski · · Score: 5, Funny

    Now I can finally get my foreskin back after 43 years without it!

    1. Re:Foreskin restoration!? by Anonymous Coward · · Score: 2, Funny

      Actually, I have it right here. I kept it in my ice-chest for a while before moving your foreskin to a more secure cryogenic facility. We had been hoping to use your foreskin along with current research into stem cells to engineer a master race of men with foreskin covering their entire bodies.

      And now I click on the Post Anonymously box...

    2. Re:Foreskin restoration!? by glwtta · · Score: 1

      You do realize that for research that requires human cells tissue from foreskin is often used? I guess it's just widely available.

      --
      sic transit gloria mundi
    3. Re:Foreskin restoration!? by Anonymous Coward · · Score: 0

      all those shmucks ...

    4. Re:Foreskin restoration!? by LittleGuy · · Score: 2, Funny

      Now I can finally get my foreskin back after 43 years without it!

      Oh great. More spam to look forward to.

      --
      Mod Karma -1: I sed bad wurds. If I cep my mouf shut, I wud be at riyses.
    5. Re:Foreskin restoration!? by Lord+Sauron · · Score: 1

      Make your foreskin bigger with herbal stem cells.

  11. Re:Stack overflow? by dspeyer · · Score: 2

    No, it's just the /. effect taking out a memory-hungry VM. You didn't expect it to hold up, did you?

  12. Re:Can we get a libertarian country first? by dbrutus · · Score: 5, Insightful

    Sorry, even a libertarian (as opposed to anarchist) society will have to deal with the question of who or what is a rights bearing being. Artificial intelligences, embryos, the retarded, catatonic, and other border conditions have to be addressed in any society that's as advanced as we are.

  13. Help! by Anonymous Coward · · Score: 1, Informative

    Does anybody have the Locus Link ID,
    Unigene ID, official HUGO name or even
    the genomic coordinates for
    the NANOG gene?

  14. Actually, Heaven does have *one* lawyer (HUMOUR) by Anonymous Coward · · Score: 4, Funny

    Following a distinguished legal career, a man arrived at the Gates of heaven, accompanied by the Pope, who had the misfortune to expire on the same day.

    The Pope was greeted first by St. Peter, who escorted him to his quarters. The room was somewhat shabby and small, similar to that found in a low-grade Motel 6-type establishment.

    The lawyer was then taken to his room, which was a palatial suite including a private swimming pool, a garden, and a terrace overlooking the Gates. The attorney was somewhat taken aback, and told St. Peter,

    "I'm really quite surprised at these rooms, seeing as how the Pope was given such small accommodations."

    St. Peter replied, We have over a hundred Popes here, and we're really very bored with them. We've never had a lawyer.

  15. Re:Stack overflow? by Anonymous Coward · · Score: 1, Funny

    The recursion is all in the xml library, pretty typical to have that deep of a tree with xml parsing.

    Having read all that I'm pretty sure what it's trying to say is "unexpected end of file" lol

  16. Stem Cell Addict by Anonymous Coward · · Score: 1, Funny

    "The one thing that's true of embryo research ... is that once people have done a little of it, they want to do more."

    Just ask Christopher Reeve about his trip to South Park. {snap! schlurrrrrp!}

  17. Re:Yes!!! lets get relion fanatics out of medicine by weorthe · · Score: 2, Insightful

    Religion does not necesarily equal morality. I'd rather not have Jerry Falwell/Pat Robertson have a say in what happens to MY genes.

    --
    cat * >> sig
  18. I resent that by Anonymous Coward · · Score: 0, Funny

    I don't live in my parent's basement.

    I live in the garage, fucktard.

  19. We need to know more than that. by Anonymous Coward · · Score: 0

    We might want to figure out how to turn it off.
    That might be a cure for cancer.

  20. Turn on? by jabbadabbadoo · · Score: 4, Funny

    Can I exploit this knownledge to turn on women, you think?

    1. Re:Turn on? by Anonymous Coward · · Score: 1, Funny

      You are better off writing a piece of code that gives a woman an orgasm when she takes a bite of the chocolate cake you sent her. Or something.

      Just don't speak in a ghey french accent when you do it.

    2. Re:Turn on? by jabbadabbadoo · · Score: 0, Flamebait
      "You are better off writing a piece of code that gives a woman an orgasm when she takes a bite of the chocolate cake you sent her. " OK - thanks for the tip.

      Deployment issues aside, I think I know how to write the program. Just needs to *push the right buttons*.

      A couple of shifts, a few rotates and a longjmp should do it.

  21. Welcome by Barkmullz · · Score: 3, Funny

    I, for one, will welcome our new master gene overlords

    --
    Ronald said nothing. He flung himself from the room, flung himself upon his horse, and rode madly off in all directions.
  22. Master gene? XX of course by Anonymous Coward · · Score: 0

    My ex in particular was always telling me what to do-

  23. SCO claims infringement by bstadil · · Score: 1
    Darl McBride at a hastily called press conference said that when they threw out the baby with the bathwater here recently they found these patents left in the tub.

    --
    Help fight continental drift.
  24. Incase anyone's interested... by Andorion · · Score: 2, Informative

    There's a cool song about stem cell research by Dream Theater, called "The Great Debate", off "Six Degrees of Turbulance" - I suggest checking it out =)

    ~Berj

    1. Re:Incase anyone's interested... by Anonymous Coward · · Score: 0

      hell yeah

  25. Master Gene? No! Mistress Gene! by screwthemoderators · · Score: 5, Funny

    A gene that tells all others what to do should definitely be feminine-

    1. Re:Master Gene? No! Mistress Gene! by Anonymous Coward · · Score: 0

      One gene to rule them all, and in the darkness punish them!

  26. Mistress Gene by screwthemoderators · · Score: 1

    The suggestiveness of S&M in the term "mistress Gene" is entirely appropriate, I might add.

  27. Don't tell me Cell Press has been /.ed by Anonymous Coward · · Score: 0

    i've tried going to the source at Cell and it gives an error message. Same thing's happening at Neuron and Molecular Cell. Don't tell me we brought the whole server down.

  28. Re:I AM TEH WINNAR!!! by Anonymous Coward · · Score: 0

    I hadn't realized it was saturday night before reading this comment.

    kool!

    props to all dead homiez

  29. Re:Can we get a libertarian country first? by maxpublic · · Score: 2, Funny

    That should've been:

    "artificial intelligence, embryos, the retarded, the catatonic, the average slashdot poster..."

    Oh wait - you were trying to avoid redundancy. My bad.

    Max

    --
    My god carries a hammer. Your god died nailed to a tree. Any questions?
  30. hmmmm by Anonymous Coward · · Score: 0

    An article about an article about an article about a cell. Sounds alot like...........(ok so I can't think of anything its like but im sure someone can)

  31. AHHHH! by Ghoser777 · · Score: 2, Funny

    "AYBABTU," then "In Soviet Russia..."

    When will the lame jokes end?!?! I only hope this valuable research will lead us towards a way to turn off the "lame-joke" gene.

    Matt Fahrenbacher

    --
    James Tiberius Kirk: "Spock, the women on your planet are logical. No other planet in the galaxy can make that claim."
  32. Take That, Pope! by E-Rock-23 · · Score: 0, Flamebait

    Religion should NOT get in the way of human progress. And this looks like human progress to me. So take that Catholic Church, take that President Dubya, and take that Religion in general. Science is the way, the truth, and the means to make humanity better.

    Let the Karma-bashing love-fest begin!

    --
    Blog Prophyts - Right On, Man
    1. Re:Take That, Pope! by thasmudyan · · Score: 1

      Amen, brother!

    2. Re:Take That, Pope! by JamochasWitness · · Score: 0

      Amen. And may Allah be with you.

    3. Re:Take That, Pope! by Anonymous Coward · · Score: 0

      How the hell is this flamebait? Oh, I get it. The moderator was a touchy fundamentalist who was afraid to lose his religion by reading the truth.

    4. Re:Take That, Pope! by Anonymous Coward · · Score: 0

      You mean science is the way, the truth, and the light. I agree. Let's build a temple to it!!! Let's ostracize those who question it!!!

  33. your .sig by Anonymous Coward · · Score: 0

    it's more like:

    "Spock ... the women on your ... planet are ... logical. No other planet ... in the galaxy can ... make that claim."

  34. Shocking cell article conclusion by Anonymous Coward · · Score: 0

    Reading between the lines of that cell article, I'm forced to conclude that God doesn't write in VB, but uses java!

  35. Re:Yes!!! lets get relion fanatics out of medicine by Anonymous Coward · · Score: 1, Insightful

    You mean religous fanatics like Louis Pasteur, yes?

  36. Reall? That's great! by Znonymous+Coward · · Score: 1

    Now if we could only find a cure of the common cold.

    --

    Karma: The shiznight, mostly because I am the Drizzle.

  37. oh nooo by Anonymous Coward · · Score: 0

    oh crap more stuff to learn about in molecular,developmental biology and genetic classes. crap!!!

  38. Re:Yes!!! lets get relion fanatics out of medicine by Anonymous Coward · · Score: 0

    Did he let his irrational religious beliefs influence his scientific work?

  39. Re:Yes!!! lets get relion fanatics out of medicine by Daniel+Dvorkin · · Score: 3, Insightful
    Watch out what you ask for. If you get those religious/moral types too far out of science you end up with Mengele reruns throwing jews into freezing water just to measure how quickly they die. It's good science but morally impermissible.
    GMAFB. Naziism was a religious ideology which directly incorporated the Christianity of the society in which it was formed ("Gott mit uns") and which furthermore inherited the idea that it was okay to kill Jews (defined, of course, by their religion) from centuries of Christian anti-Semitism. I am sick to death of people citing Mengele as a favorite example of "why science needs religion" when a) Mengele was himself a religious man, and b) religion has never shown any special aptitude for morality, in science or anywhere else.

    Can you give give me one single solid example of a time when religious restraint on scientific research has done more good than harm? (I assure you, history is full of examples of the reverse.) A single one? Apparently when religion and morality are invoked, we're all supposed to stroke our chins and nod wisely and say, "Hmmm, well, of course, science requires religious morality to control its excesses." It's bullshit. If I have to choose between superstition and ignorance and morality-by-authority on the one hand, and a longer, happier, healthier life for myself and the people I love on the other, I know which one to pick.
    --
    The correlation between ignorance of statistics and using "correlation is not causation" as an argument is close to 1.
  40. Old news by Ambush · · Score: 2, Funny
    I saw Russell Crowe regenerate his cells last night in Virtuosity. Of course, he used glass rather than stem cells, but it was a neat party trick anyway.

    ;-)

    --
    There are 10 kinds of people; those who know ternary, those who don't, and those now hunting for a dictionary.
  41. Convert DNA to Binary... by SharpFang · · Score: 2

    and you'll see in the beginning of the gene:

    int main (int argc, char** argv)
    { ...

    --
    45 5F E1 04 22 CA 29 C4 93 3F 95 05 2B 79 2A B2
    1. Re:Convert DNA to Binary... by GreyWolf3000 · · Score: 1
      Actually, more like:

      10 PRINT "ENTER A CHOICE:"
      20 PRINT "1) GROW"
      30 PRINT "2) DIVIDE"
      PRINT "3) DIE"
      40 INPUT A

      --
      Slashdot: Where people pretend to be twice as smart as they really are by behaving like children.
    2. Re:Convert DNA to Binary... by Anonymous Coward · · Score: 0

      well if you actually did convert it into binary you would have a string of '1's and '0's.

  42. Alfas, betas, deltas, morlocks by Anonymous Coward · · Score: 0

    Not necessarily in that order.
    Considering the resounding success of televangelism, shopping channels, politicians, a considerable portion of what passes for entertainment and information (increasingly siamesed, artificial and vacuous)... They would seem to be doing fine !

  43. How to Turn On A Stem Master Cell by thedbp · · Score: 4, Funny

    1. Put on some smooth jazz or R&B. Al Green will do nicely.

    2. Light some candles and incense. Sandalwood is perfect, especially if you can get some sandalwood massage oil.

    3. Compliment the Stem Master Cell heavily, even if you don't believe a word of what you're saying.

    4. Offer a deep-fetal-tissue massage.

    5. After a nice 20 minute session, rub the Stem Master Cell's buttocks and thighs, hightening their pleasure with small injections of dopamine.

    That should do it! Lord knows it works for me.

    1. Re:How to Turn On A Stem Master Cell by Anonymous Coward · · Score: 0

      forgot:

      6. !Profit!

  44. Re:Yes!!! lets get relion fanatics out of medicine by Anonymous Coward · · Score: 1, Funny

    Well I wanted to nuke china to prevent SARS from spreading, but my pastor talked me out of it.

    </troll>

  45. Re:Yes!!! lets get relion fanatics out of medicine by dbrutus · · Score: 1

    The problem of a Mengele appearing is not theoretical but historical. The example I gave was all too real and the research data was under embargo for decades after WW II. From a purely scientific point of view this was and is bad science.

  46. Re:Yes!!! lets get relion fanatics out of medicine by dbrutus · · Score: 3, Insightful

    Naziism, formally called national socialism, was very much not christian which any serious examination of their belief system would bear out. It's an anti-christian libel to view Nazi denial of jewish humanity as different only in degree with christian fury over the christ-killer libel. Christians were angry with jews over what their ancesters did, Nazis believed that inherently the jews were subhuman. And christians, unlike nazis, have doctrines of love and forgiveness that tended to ameliorate anger.

    It was the denial of humanity that allowed all those medical experiments to be done as if jews, homosexuals, gypsies, and the other inmates of the death camps were just animals that could be used as means to nazi ends.

    As for religious restraint doing more good than harm, how do you determine the good and harm of an experiment that was not run? Medical ethics boards don't tend to trumpet to the public the immoral ideas their staff come up with that they shoot down. As an alternative, I'd look at the history of immoral scientific experiments that could have used a bit more moral supervision. I'd suggest a little more restraint on the part of they doctors who refrained from treating those black syphilis patients with more than a placebo just so they could record 'what would happen' would have been a good thing.

  47. FOAD is now obsolete by Anonymous Coward · · Score: 0

    see subject

  48. Well, duh!!! by commodoresloat · · Score: 1

    Of course He uses java. Where's he gonna find VB programmers in heaven???

  49. "The Great Debate" by AvantLegion · · Score: 1
    Has anyone listened to Dream Theater's "The Great Debate"?

    After listening to that song, I can't read any discussion about stem cell research without rolling my eyes over that stupid song. :)

    1. Re:"The Great Debate" by Anonymous Coward · · Score: 0

      Dream Theatre are playing oin Toronto this summer and I am definately going.

      The best technical musicians on the face of the planet.

      JOHN PETRUCCI OWNS ALL !!

  50. Re:Yes!!! lets get relion fanatics out of medicine by I(rispee_I(reme · · Score: 1

    Yes, and there is certainly no way to appreciate one's fellow humans without gettin' Jesus... I would actually say that an atheist with morals is superior to a christian with morals, because the atheist acts decently with no heavenly reward dangled in front of him.

  51. last words to a bishop? by denny_d · · Score: 1

    Typical of the washington post's slant. They leave the last words to a bishop
    "The one thing that's true of embryo research," Doerflinger said, "is that once people have done a little of it, they want to do more.

    I'm always curious to see how the mega-medias treat stories to reflect their stockholders/ chairpersons political and religious interests.

    Does anyone know where I can find a topic map of the big media ownership and their political affiliations?

    I found this one pretty easily...
    Washington Post's Media interests

    1. Re:last words to a bishop? by m1chael · · Score: 1

      the one thing true of religion is that once people have done a little of it, they want to do more. ahhhhhhhhhhhhhhhhhhhh.

      fear leads to anger leads to the dark side.

      --
      I know you are psychotic, but please make an effort.
    2. Re:last words to a bishop? by Rick+Richardson · · Score: 1

      They asked me first, but decided not to use my words, which were:

      Scientists will achieve human immortality by 2100. Do you want the
      government (you) to pay for *me* to live forever? Think about *that* before
      voting for government insurance programs. I could be around a long time.

  52. Tree Of Life_root access by Anonymous Coward · · Score: 0


    Genesis 3:22-24

    22. And the LORD God said, Behold, the man is become as one of us, to know good and evil: and now, lest he put forth his hand, and take also of the tree of life, and eat, and live for ever:

    odd that there is little or no serious thought and speculation as to why ..

    something that on the surface would aper to be a good thing .. ie. to know what is good and what is evil ..

    actually turn out to be the source of all mans troubles:

    couldn't be ..

    that with only 2 points of reference all that i can do is draw straight lines in space .. with absolutely no relativity .. which requires at the very least 3 point for a plainer perspective and a minimum of 4 points if 1/we desire multi-dimensional perspective .. good and true perception

    the ROOT of/for divine logic is:

    either/or can never be enough .. i/we must at the very least know what is and/or

    if i/we seek only to know whether something or someone is good or evil .. i/we will never know what is good and true

    i/we must know what is both good and true: for not all that is good is necessarily true and not all that is true is necessarily good ..

    23. Therefore the LORD God sent him forth from the garden of Eden, to till the ground from whence he was taken.

    24. So he drove out the man; and he placed at the east of the garden of Eden Cherubims, and a flaming sword which turned every way, to keep the way of the tree of life.

  53. I still have MY foreskin by Anonymous Coward · · Score: 0

    And I LOVE it! No snipping for me, thank you!

  54. Finally! by gad_zuki! · · Score: 0

    >eliminating the need to destroy embryos to get them.

    Now they can rest where god intended them to rest, in the dumpster behind the clinic or finally tossed out en masse when storage costs outweigh potential profit at the fertility clinic. Heaven forbid this waste actually does some good for someone somewhere!

    It's really going to hurt when European and Asian drugs based on stem research, patented of course, hit the markets here in the States with a huge mark-up.

  55. Re:Yes!!! lets get relion fanatics out of medicine by PenguiN42 · · Score: 1

    Science may require some kind of morality or ethics -- just like everything else does; however, Morality and ethics do not require religion.

    --
    The following sentence is true. The preceding sentence was false.
  56. Re:Yes!!! lets get relion fanatics out of medicine by Anonymous Coward · · Score: 0

    Don't blame ALL religion when you really mean Judeo-Christian. Would we have this science-religion gap if we were Muslims or Buddhists?

  57. Useful to find this gene role in cancer by Muhammar · · Score: 3, Interesting

    A lot of tumor cells use signaling pathways which are activated normaly only in embryogenesis - turning the cell signaling off is a new promising way to treat cancer without the typical debilitating chemotherapy side-effects. The ability to switch this master stem-cell gene off could be useful in this respect.

    --
    I doubt that we will ever figure out - and I suspect that even if we did figure out we couldn't do much about it
  58. Already Discovered! by Skynet · · Score: 1

    The master gene was discovered decades ago :)

    --
    Execute? [Y/N] _
  59. Indeed not by uberdave · · Score: 1
    Patent 0: Wisdom

    12 "I, wisdom, dwell together with prudence; I possess knowledge and discretion. 13 To fear the LORD is to hate evil; I hate pride and arrogance, evil behavior and perverse speech. 14 Counsel and sound judgment are mine; I have understanding and power. 15 By me kings reign and rulers make laws that are just; 16 by me princes govern, and all nobles who rule on earth. [1] 17 I love those who love me, and those who seek me find me. 18 With me are riches and honor, enduring wealth and prosperity. 19 My fruit is better than fine gold; what I yield surpasses choice silver. 20 I walk in the way of righteousness, along the paths of justice, 21 bestowing wealth on those who love me and making their treasuries full. 22 "The LORD brought me forth as the first of his works, [2] , [3] before his deeds of old; Proverbs 8:12-22
  60. Re:Yes!!! lets get relion fanatics out of medicine by kramer2718 · · Score: 1

    Ha! Pretty Funny! Did anyone else get this? Where are my mod points when I need them? I just let 4 points expire yesterday...

  61. Religious History by PsiPsiStar · · Score: 2, Interesting

    >Christians were angry with jews over what their >ancesters did

    Allegedly did. One gospel account has the Romans holding Jesus's trial, another account has the Sanhedrin holding the exact same trial.
    So one of the gospels violates a commandment and bears false witness.

    >And christians, unlike nazis, have doctrines of >love and forgiveness that tended to ameliorate >anger.

    Individual Christians may live by such doctrines, but historically and politically pogroms, murder, and severe economic sanctions were commonly used by religiously oriented governments (Christians included) as a form of political control which played on feelings of religious nationalism. The Vatican was openly in support of Hitler, then tried to erase its involvement afterwards. The tremendous support given to Nazism by religious institutions was not an accident.

    It seems that the political usefulness of religion is to help individuals to assert their moral superiority over others, and then use that superiority to justify expansion and or exploitation. Christianity may make its followers well disposed towards other Christians, but it has rarely, from what I have seen, increased the acceptance of various 'outsiders' (whoever those happen to be at the time) by Christians. The Quakers were one possible exception. Our modern emphasis on tolerance is more a novelty than the rule.

    --

    ___
    It's the end of my comment as I know it and I feel fine.
    1. Re:Religious History by Anonymous Coward · · Score: 0

      Allegedly did. One gospel account has the Romans holding Jesus's trial, another account has the Sanhedrin holding the exact same trial. So one of the gospels violates a commandment and bears false witness.

      This is just dumb. There were two trials, (as is CLEARLY documented in the Bible). The Romans allowed the Sanhedrin to exist solely as a puppet government over the Jews. The Sanhedrin tried Jesus and found him guilty, then had to take him to the Romans (Pontuis Pilate) to legally get him sentenced to death. Pilate did not want to crucify Jesus because, since he wasn't a Jew, in his eyes Jesus had done no wrong.

      Typical atheist, basing all of your ideas about Christianity on half-truths and misconceptions. If you're talking about something as important as how you're going to spend eternity, shouldn't you at least check out the one religion that says if you don't do it their way you're going to spend eternity in pain and anguish? To NOT check it you would have to be a pretty ignorant, close-minded person, wouldn't you?

    2. Re:Religious History by Anonymous Coward · · Score: 0
      Allegedly did. One gospel account has the Romans holding Jesus's trial, another account has the Sanhedrin holding the exact same trial. So one of the gospels violates a commandment and bears false witness.
      Oh please. This is a sophomoric argument that relies on a sophomoric reading of the gospels. There have been centuries of efforts in trying to show such obvious contradictions in the Biblical narrative, but if you read it using the most basic historical and literary discipline, you aren't left with any of these bumper-sticker criticisms of the Biblical narrative holding up under scrutiny. Every time someone thinks they have the bumper sticker, or the thesis, that puts irrefutable holes in the Biblical narrative, someone else comes up with a bumper sticker, or thesis, that suggests an alternative explanation. Not just the you-can-read-into-it-whatever-you-want kind of suggestion, but well-founded, solid working hypotheses. Such as the obvious need to take into account the different vantage points of the writers of the four books collectively referred to as the Gospels.

      As soon as I saw this opening line of your post, I simultaneously thought "poor uneducated sophist" and "troll." I'm not sure which it really is, but I'll give you the benefit of the doubt and assume it was the second, and that I am merely satisfying your desire to see somebody post this obvious response.

      One of the greatest tragedies of our time is that we have a world full of people with graduate-school level understandings of their specialties but elementary-school understanding of the claims of the Biblical narrative and the claims of Christ.

      I'm posting anonmymously, because this doesn't seem to be worth wasting karma on, posting it just to have a bunch of knee-jerk /.ers label it as flaim-bait or something...
    3. Re:Religious History by juhaz · · Score: 1

      One of the greatest tragedies of our time is that we have a world full of people with graduate-school level understandings of their specialties but elementary-school understanding of the claims of the Biblical narrative and the claims of Christ.

      Tragedy? Where? People have graduate-school level understandings of their specialties. They need to. Those specialties are real, and can be used in real life.

      On the other hand, people DO NOT, need thorough education on storybooks such as bible, koran, adventures of the mickey mouse, and other equivalently true books just because someone, somewhere, happens to hold them "holy". Elementary knowledge of these so called religions is more than enough, and even that should center equally on them all, rising people to christians by force is not any goal, and that specific religion has no more factual basis than any of those other tales, if a person wants to study these works of fiction or even worship one of their imaginary deities, it should be solely his/her own decision and not something dictated by society.

    4. Re:Religious History by Anonymous Coward · · Score: 0

      More troll, I presume.

      But Christianity has always flourished where intellectual exchange is most free, and the culture engendered by Christianity has led to more scientific advances than those made by all other cultures. Slashdot is not such a place (of free intellectual exchange), because it is full of people like you who don't really know squat about the Biblical narrative or the claims of Christ. So the price of entry to *real* debate is too high, and people who know more about Christianity tend to hang out other places, where they are more likely to find open-minded people.

      Hiding behind the little cultural trendlet of Scientism (which is pretty much the mainstream religion of Slashdot) will not, in the end, make you look any wiser than last century's Darwinist (which is fast becoming a scientific dead-end) or the flat-earth society that came before that.

      The universe, under any degree of scrutiny, has always behaved in ways that are consistent with the Christian conception of the universe, and Christianity itself is a self-consistent set of assertions that do exclude other religions. But hey, it's trendy to look arrogant and philosophically naive, so go ahead and keep talking like this. Maybe some day you'll have the good fortune to say something like this in front of somebody a) who knows better and b) whom you respect enough to listen to.

      On that day, you might begin to see past all these sophomoric presumptions that you have welcomed as others have crammed them into your cranium and down your throat.

    5. Re:Religious History by juhaz · · Score: 1

      Not a troll. But truth hurts, like always, so you must escape behind that excuse.

      But Christianity has always flourished where intellectual exchange is most free, and the culture engendered by Christianity has led to more scientific advances than those made by all other cultures.

      Indeed. Like middle aged most overtly christian europe where all scientific development was at almost total still, and no wonder, do something scientific and all those wonderful open-minded christians come and burn you as a wich. They didn't even manage to reclaim knowledge found by greeks and romans thousands of years earlier!

      Right after the stranglehold of christianity broke, people broke into renaissance in sciences and arts, and pace of scientific discovery has from that point accelerated constantly towards this day - while christianity has at same time diminished and become more of a fashion than anything most people take serious any more.

      So the price of entry to *real* debate is too high

      There can never be a real debate between biblists and people who follow real scientific princibles. Your precious book has no other proof than itself! But that is enough for Christians, they don't want Knowledge, nor Truth, they only want to Believe.

      will not, in the end, make you look any wiser than last century's Darwinist (which is fast becoming a scientific dead-end)

      Darwin could obviously not know everything we do after recent advantages of biology, and his theory reflects it, but its basic princible is, and will be valid for a very long time. There are no viable alternatives for evolution. Creationism and its advocates has never been any more than a joke. Not even funny one. Hopefully I didn't lower myself to argue with one.

      or the flat-earth society that came before that.

      Very christian society, if I may remind you, based on direct interpretation of bible, interpretation that is still valid, and will always be, with dozens of others equally valid interpretations. Because bible is full of misinformation and is inconsistent even with itself.

      The universe, under any degree of scrutiny, has always behaved in ways that are consistent with the Christian conception of the universe

      Yeah, it was created in a week or so, about four (or was it six?) thousand years ago, world is flat and all the other universe is circling around it, et cetera.

      Oh wait. Under any degree of scrutiny, christians have always changed their conception of the universe whenever new information has been uncovered (information that they couldn't silently bury, by burning its discoverer or otherwise).

      Christianity itself is a self-consistent set of assertions that do exclude other religions.

      Christianity is everything but consistent, and every monotheistic religion does by definition exclude other religions. All those other religions and their assertions are just as viable and valid as christianity.

      But hey, it's trendy to look arrogant and philosophically naive, so go ahead and keep talking like this.

      I don't tend to follow trends, and I've always been direct with my words for followers of imaginary deities. And no offence but if anything is naive and childish, it's believing in those said entities.

      Maybe some day you'll have the good fortune to say something like this in front of somebody a) who knows better and b) whom you respect enough to listen to.

      I hope the same for you. Sadly, fanatic christianism excludes any person from belonging to either groub a or b. Blindly clinging to dying god doesn't earn a person knowledge or wisdom any more than respect from me.

      On that day, you might begin to see past all these sophomoric presumptions that you have welcomed as others have crammed them into your cranium and down your throat.

      On that day, you might begin to see the Light of knowledge past all these tales and superstition crammed into your, and your ancestors, craniums for last few thousand years. And by the way, nobody has crammed anything, my opinions are totally my own, and I feels sad for persons who don't have that freedom, because even their private thinking is bound by that imaginary god.

    6. Re:Religious History by PsiPsiStar · · Score: 1

      Umm... but I'm not an atheist.

      --

      ___
      It's the end of my comment as I know it and I feel fine.
    7. Re:Religious History by PsiPsiStar · · Score: 1

      translation: you disagree with me so you're going to insult me a little bit.

      You didn't even seem to grasp the point of what I was writing. If we take the New Testament standard of 'judging a tree by its fruit' then we have to come to grips with the notion that Christian society (as well as other societies) has frequently used religion as a tool throughout history in the process of nationbuilding and of separating 'us' from 'them'.
      i.e. 'do you worship the local god(s)?'

      In short, I was arguing against the notion that the Christian history of Germany was incidental to the nationalism, the anti-semitism and the anti-gypsy attitudes.

      --

      ___
      It's the end of my comment as I know it and I feel fine.
  62. Re:Yes!!! lets get relion fanatics out of medicine by jaelle · · Score: 1
    Sigh...the religious propaganda machine grinds on...

    "You find as you look around the world that every single bit of progress in humane feeling, every improvement in the criminal law, every step toward the diminution of war, every step toward better treatment of the colored races, or every mitigation of slavery, every moral progress that there has been in the world, has been consistently opposed by the organized churches of the world. I say quite deliberately that the Christian religion, as organized in its churches, has been and still is the principal enemy of moral progress in the world." Bertrand Russell

    "The great religious ages were notable for their indifference to human rights . . . not only for acquiescence in poverty, inequality, exploitation and oppression, but also for enthusiastic justifications for slavery, persecution, abandonment of small children, torture, and genocide. . . . Moreover, religion enshrined hierarchy, authority, and inequality. . . . It was the age of equality that brought about the disappearance of such religious appurtenances as the auto-da-fe and burning at the stake." Arthur Schlesinger Jr.

    "The slave trade flourished with the approval of the Church, and in Britain and America it was the established churches that fought most vigorously against abolition. . . . Bible texts . . . were used constantly to support slavery. Opponents of slavery, including Wilberforce and Paine, were savagely attacked by the churches for presuming to know better than the Bible, and the antislavery attitude of the Quakers made them unpopular with orthodox Christians. Wilberforce . . . complained that his supporters were nonconformists and atheists, while church people generally opposed him." Carl Lofmark

    "Historian Larry Hise notes in his book Pro-Slavery that ministers 'wrote almost half of all defenses of slavery published in America.' He listed 275 men of the cloth who used the Bible to prove that white people were entitled to own black people as work animals." James Haught

    "Abolitionists failed to win the churches to their cause. In 1837, the Presbyterian General Assembly 'excised' from the church its most thoroughly antislavery synods. No major denomination endorsed abolitionism. This reluctance on the part of clergymen and church bodies was to have profound consequences for the course of the antislavery movement. It helped push Garrison and others into taking militant anti-clerical stands, and it caused the movement in the later 1830s and 1840s to adopt increasingly secular policies." Merton L. Dillon

    "In all the ages the Roman Church has owned slaves, bought and sold slaves, authorized and encouraged her children to trade in them. . . . There were the texts; there was no mistaking their meaning; . . . she was doing in all this thing what the Bible had mapped out for her to do. So unassailable was her position that in all the centuries she had no word to say against human slavery." Mark Twain

    "The delegates of the annual conference are decidedly opposed to modern Abolitionism and wholly disclaim any right, wish, or intention to interfere in the civil and political relation between master and slave as it exists in the slave-holding states of the union." Methodist Episcopal Church, 1836 General Conference, Cincinnati

    "It [slavery] has exercised absolute mastery over the American Church. . . . With the Bible in their hands, her priesthood have attempted to prove that slavery came down from God out of heaven. They have become slaveholders and dealers in human flesh." William Lloyd Garrison, abolitionist leader

    "I assert most unhesitatingly, that the religion of the South is a mere covering for the most horrid crimes - a justifier of the most appalling barbarity, a sanctifier of the most hateful frauds, and a dark shelter under which the darkest, foulest, grossest, and most infernal deeds of slaveholders find the strongest protection. Were I to be again reduced to the chains of slavery, next to that enslavement, I should regard being the slave of a religious master the greatest calamity that could befall me. . . . I . . . hate the corrupt, slaveholding, women-whipping, cradle-plundering, partial and hypocritical Christianity of this land." Frederick Douglass

    --
    You have the right to remain silent. Anything you say will be misquoted, then used against you.
  63. You forgot... by Anonymous Coward · · Score: 0

    to site "The complete left-wing history of Western Religeon" as your source....

    I am serious...for fucks sake people, get over it. Not all Western Religeous people (Christians included) are what you want them to be in your own mind. Consider reading some other books and taking a history class NOT at Berkley. The truth lies somewhere in between.

    1. Re:You forgot... by ChrisMaple · · Score: 1

      Don't confuse anti-religion views with leftist views. There's plenty of capitalist philosophy that considers religion a hideous evil.

      --
      Contribute to civilization: ari.aynrand.org/donate
  64. Er, I think you're reading dated text by CharlesClarkson · · Score: 3, Funny

    According to: The Gesargenplotzian Gospel

    IV. 1. Lo, in 1962 the Great Gesargenplotz came back, and it saw what He had done. And the Great Gesargenplotz was wroth, and it spoke unto Him saying "Why have you done this? Why have you created these creatures just to torment them?" 2. And He answered, saying "I have done so because it amuses me, Great Gesargenplotz. Of what matter is their pain and disappointment? They are not gods as you and I, they exist only for my amusement." 3. The Great Gesargenplotz, hearing His answer, knew that His heart was hard. The Great Gesargenplotz repented it that it had made Him. 4. The Great Gesargenplotz ate Him and He was no more.

    After being eaten by His creator, I think His patent lapsed.

    --

    Charles K. Clarkson
    Many people truly want to help. Unfortunately, many people truly suck at it.
  65. Re:Yes!!! lets get relion fanatics out of medicine by Planesdragon · · Score: 1

    Science may require some kind of morality or ethics -- just like everything else does; however, Morality and ethics do not require religion.

    If by "religion" you mean "theism," then you're right.

    But, at the very least, to be moral you need to have some claim as to the worth of others / the whole of humanity. A self-centered viewpoint, which is emminently logical, is the very essence of amorality--and what logically a person will have if they do not believe in the worth and value of SOMETHING other than themselves.

    The bare minimum to be moral is not "belief in the almighty" or "belief in the beyond" or even "belief in humanity", but a faith that if you are moral to others then others will be moral to you.

    Thankfully, this can be proven through observation of how humans behave socially.

    Historically, of course, great moral humans (who set the tone for the whole of our society) have been rather religious--and those that have not have had a "religous feeling" towards something else greater than themselves.

    And, as for the "relion fantaics" meddling in medicine--it's just a semi-religous argument as to the personage status of a fetus. If a fetus is a living person, then it's unethical to kill them or profit from their death. If it's not as person, it is ethical to euthanise them and learn / profit from their death.

    The religious overtones of the arugment are coincidences--the various clergy could just as easily be arguing that a fetus is no more than a part of the mother, and can be treated as a spare kidney or bundle of hair.

  66. Re:Poon Tang by Anonymous Coward · · Score: 0

    I'd be gettin' some tonight, but I got plenty this morning from the missuz and we have a long drive ahead of us tomorrow to see the in-laws and eat barbecued ribs :)

  67. What? by Anonymous Coward · · Score: 0

    So we didn't have to kill all those babies after all? We could've just done more research and spared human lives? Doh!

  68. Re:Take That, Pope! ( a bit offtopic ) by anubi · · Score: 1
    Ok.. since you brought up Religion getting in the way of human progress, let me run my belief system up the flagpole and see if anybody salutes it, or if they piss on it.

    Given... God made the Universe.. Heavens, Earth, and everything in it. I am not stating what God is, or how "he" did it. I have no idea. I have been looking for 40 years now without much luck.

    Science is the study of God's Creation. I choose to let Creation itself bear witness of the Creator. I consider the Laws of Physics to be God's Law. He created them. I certainly didn't. Scientists are recognized for observing and documenting a relationship, but name me any scientist that dictated the mechanization. Anybody here can change the charge of an electron? Only God can do that. And don't take me as a religious nut - I get in extremely heated arguments with every darned religion I come in contact with. Even the Bible itself describes how much deception is involved in searching for God. Many passages. If Science is the study of God's Creation, then I see Science itself as the ultimate study for verification of God.

    I see all these lengthy texts from antiquity, but yet these were written by MAN. Of course, they say "Inspired by God".. but I am writing this right now, and I feel "Inspired by God" too. Does this make me a prophet? I hope not, for I don't have anything more than speculative reports at this time. I just want the TRUTH. I've known MAN for way too long and know he will tell me anything to get me to follow him. ( Leadership skills ).

    My prime fear on religion has to do with the propensity of men to "create" a superior when they want authority to boss other men around, but don't want to take responsibility for their decisions. Its kinda like the business types that can make a decision, but if you press them for one that they don't want to make, they will come up with the line that they don't have authority to do it and will bring it up to the "committee". Knowing how the human psychology mandates pecking orders so heavily, how do I discriminate between That who Created the Universe, and something somebody made up long time ago? They speak many words, but offer no proof, citing "faith". C'mon now, am I to believe in a God that is sold like a bad investment? What do they take me for?

    Science is the only thing I have to go on. Something demonstrable.

    All this study on Genetics to me is just further study of God's Creation. God put it here for us. If whatever created us did not want us messing with it, we would never be able to comprehend it. Can you imagine cats studying genetics? If God had wanted a bunch of bleating sheep, He could have left it as such.

    And as I stated, although I often use the word "He" to reference the deity, I have no idea what I am dealing with. Lacking anything definitive, I often see nebulous phrases such as "spirits" used as a descriptor.

    I don't think the problem is so much what we know, its whether or not we can develop the wisdom of knowing what to do with it. Knowlege can be used for great good, or great evil. Our choice. If you pray for anything, pray for Wisdom.

    --
    "Prove all things; hold fast that which is good." [KJV: I Thessalonians 5:21]

  69. Comeback #2 by Anonymous Coward · · Score: 0

    "Why have lawyers when you're the judge?" asks the Diety, "Then again how many cases can I win, when everyone who sits on the witness stand either swears by me or at me?"

  70. Re:Yes!!! lets get relion fanatics out of medicine by lee1 · · Score: 1
    Nazism [...] was very much not christian

    The comment that you reply to was so very well expressed that I feel a need to defend it. He did not say that Nazism was Christian. Read it again. What he did say is very rarely brought up, because it is so potentially troubling to Christians. It is also practically self-evident. Nazism did not arise in a vacuum; it was adopted by a community of Christians with a horrible history of violent antisemitism that preceded Nazism. Read about the treatment of Jews in 19th century Germany. The Nazi policy toward Jews was an elaboration and formalization of that preexisting attitude. Without that Christian kernel of hatred toward the Jews, Nazism could not have taken hold.

    [...] look at the history of immoral scientific experiments that could have used a bit more moral supervision

    He was not arguing against moral restraint. Religious influence is not moral influence, it is religious influence. Morality must overcome religion; ethics must not be usurped by superstition.

  71. Nazism != Christianity by Anonymous Coward · · Score: 0

    Anymore than Likkudism == Judaism

  72. Re:Yes!!! lets get relion fanatics out of medicine by Anonymous Coward · · Score: 0

    The Nazi's also exterminated quite a few Christians who didn't agree with their views and actions. Alot of people like to forget that or leave it out of the history books, but the original poster needs a reality check...they were not Christians reguardless of what they chose/choose to call themselves.

  73. All your cells have the same genes by sam_handelman · · Score: 1

    Briefly, for those who went to high school here in the states:

    Gene (DNA) -> RNA -> Protein

    So, each Gene makes a single Protein product.

    Reearchers have found the Gene that makes the protein product that causes a cell to behave as a stem cell. This Gene is found in every cell of your body, but, under normal circumstances, the protein product is found only in stem cells.

    While I'm clearing things up I might as well explain some more.

    Melanin, for example, is the pigment that turns your skin brown. The gene to make melanin is found in every cell of your body, however, the cornea (whites of the eyes) of a black person is not black. The gene to make melanin is inactive in those cells.

    Likewise, this stem cell gene is inactive in most cells of your body.

    Different forms of a gene (called alleles) make slight variations of the same Protein product, or make the same protein product under different circumstances.

    For example, both a white person and a black person have the gene that makes the protein melanin, which is a dark brown pigment found in both skin and iris.

    A white person, with brown eyes, has a gene which is less active in the skin, makes less melanin there, and the skin is paler (forms of melanin which are less dark also exist). A black person has a gene which is more active in the skin.

    A white person with brown eyes, however, probably has every bit as much melanin in the iris (the colored part of the eye,) as the black person. So, the melanin gene is differentially active only under some circumstances.

    This differential activity is mediated by transcription factors. Transcription factors are switches that turn genes on and off, they are present in some tissues but not others. The white person has an allele of melanin which doesn't not respond to the "on" switch (or responds weakly) found in the skin, but still responds to the seperate "on" switch found in the iris.

    The gene this group has discovered (nanog) is an example of a transcription factor; more accurately, the protein product made by nanog is a transcription factor. It allows genes to be activated ("expressed" is the term) in a human embryo but not in an adult, or vice versa.

    --
    The good and new comes from no quarter where it is looked for, and is always something different from what is expected.
  74. Long healthy lives - maybe by tonyl · · Score: 1

    I've often thought that it won't be too long before all disease can be cured. I doubt I'll live long enough to see it, but I bet my children will.

    That of course assumes that the religious right doesn't screw it up, that world conflict doesn't drive us back into the stone age, and that large rocks don't come raining down on us from outer space.

    If it does come to pass, it's interesting to think about how societies will change. If I had several hundred years of healthy living to look forward to, there are so many things I'd want to learn..

    I would think that human life would become more precious too: longevity might even be a disincentive to war. There would always be deaths from accidents, but population growth would have to be carefully managed.. and so many other effects..

    --
    -- Tony Lawrence
    1. Re:Long healthy lives - maybe by crashnbur · · Score: 1
      Evolution works two ways. We get better at defending against one thing, and something else develops. That is to say, human beings are not the only thing developing in the natural world, and human beings can never outpace nature. No matter how good we get at immunizing ourselves, there will always be something worse to be discovered or set upon us.

      My theory: the only we could ever cure ourselves from all diseases would be for everyone to die from everything they've ever gotten, leaving only the few lucky, healthy, uninfected of us. Of course, proper removal of the infected bodies could pose a problem...

      The world is too big, and something big or small will alway be plaguing it. If we ever seem to have immunized ourselves completely, the resulting complacency will be our undoing.

    2. Re:Long healthy lives - maybe by tonyl · · Score: 1

      Consider your computer.

      No matter what breaks, it can be repaired. The time, effort and expense may not be justified, but you CAN fix it. Why? Because the technology is completely understood.

      We don't understand the technology of cells yet, but we are heading in that direction. Again, barring disruption by our own stupidity or natural disaster, there will come a day when we can "fix" anything biologically wrong because we can fix or replace cellular machinery. It doesn't matter what "comes along" if you really understand the technology: whatever it is, you can fix it.

      It's easy to imagine little machines running through your body repairing cellular damage or just replacing defective cells with healthy versions. Your body already has such mechanisms, but someday we will improve on what evolution has provided. Evolution does accomplish wonderful things, but it gets there by blunder: if we understand the mechanics fully, we should be able to do much better. Someday. Probably long after I'm gone, but you never know: sometimes things happen faster than you expect.

      Consider that if the ability to do all that perfectly is a thousand years away (probably isn't, but..), all you need to do to be there for it is to survive long enough that the technology pushes you along to the next advancement. In other words, if you can live until the technology could push you to two hundred years, during that next period it might advance yet again and so on.

      I really believe that people in their twenties now have a real shot at living "forever" (whatever that means).

      Of course there's nothing like superstition, prejudice, ignorance and general stupidity to screw that up.

      --
      -- Tony Lawrence
    3. Re:Long healthy lives - maybe by crashnbur · · Score: 0
      I disagree, and here's why.

      First, I should say that I agree with your idea that we can fix anything, ignoring expense, given a complete understanding of a given technology. Your point is very well illustrated.

      However, I believe that a complete understanding of exactly what makes the human body tick is one of those cosmological mysteries that will never be fully solved. A prerequisite for such understanding would be to have a little one-on-one with God himself, or to actually figure out the very first thing that happened in this universe. We would have to know the nature of the cosmic order, what makes stuff stuff, what makes life live, etc.

      Then again, I will not rule out the possibility that the "technology" of the human body may be a bit simpler than that; however, my limited understanding of why life works the way it does gives me the opinion that organic things are far more succeptible to the technological limitations of infinite possibilities. That is, an organic thing -- more specifically a living organism -- is not likely to fully understand itself simply because it is not a higher being than itself.

      I consider full human understanding of the human body to be an asymptote on a graph ... we may keep getting closer and closer, but we'll never quite get there, simply because there is no higher being there to guide us, and the probability that our stumbling will lead us in the right direction without such a guide is 1 in infinity (but, well, I guess that means there's a chance...)

      (I would love to re-write this argument into a better-arranged, more thoughtful essay... if I weren't so damn lazy.)

    4. Re:Long healthy lives - maybe by tonyl · · Score: 1

      Well, stick around, you'll probably be proved wrong.

      Ever since the first glimmerings of scientific thought people having been asserting that such and such is just too complicated and will never be understood.

      Life is nothing but sufficiently complex chemistry, and chemistry is nothing but applied physics. Of course if you have religious beliefs that insist otherwise, you probably won't ever believe that, and I'm not a bit interested in trying to convince you. However, I am fully convinced, and already biology and chemistry are getting very chummy at their unions. In its turn, chemistry will yield to physics eventually. At that level, it may be true that we can't fully understand certain interactions - or at least can't predict individual events with perfect accuracy. But that doesn't matter in the larger world, does it? An individual atom
      may indeed move unexpectedly for reasons we may never be able to grasp, but we still know that if you boil water you mostly get steam. It's reliable, predictable, and understandable. We'll reach the same level with biology, chemistry and physics eventually.

      As to the argument that we can't ever understand ourselves, that's a philosophical position I have no patience with. We are quite obviously made of higher level structures that in turn are built from lower level structures. We are learning more and more about the chemistry and the mechanics of cells, and we've haven't needed any "guide" to help us . Again, your religious beliefs may say otherwise and I again have no desire to argue about that.

      Nor am I overly interested in arguments that draw on the idea that a program can't prove itself correct. That's all well and good, but a program COULD repair another program that was under assault from bit changing viri.

      So: if we know the mechanics of a cell and are capable of repairing or duplicating it, we have all we need for effective immortality (ineffective when exposed to sudden nuclear blasts at close range, of course).

      Of course if you think life didn't come from chemistry, if you instead think that gods designed it all, that's your right and I am all in favor of whatever makes you happy. But I do think it's pointless to invoke the God argument in a discussion like this. If you believe in such things, then of course we may never be able to understand life, and there's no point (as far as I am concerned) in discussing whether that God did or did not make it simple enough for us to tinker with. It may be an interesting theological argument, but such things are of no interest to me.

      If you leave superior beings out of it, we will understand cellular chemistry. Count on it.

      --
      -- Tony Lawrence
    5. Re:Long healthy lives - maybe by davesag · · Score: 1
      would love to re-write this argument into a better-arranged, more thoughtful essay... if I weren't so damn lazy.

      See Godel's Theorem. In summary: All logical systems of any complexity are, by definition, incomplete; each of them contains, at any given time, more true statements than it can possibly prove according to its own defining set of rules. This theory has been taken to imply that you'll never entirely understand yourself, since your mind, like any other closed system, can only be sure of what it knows about itself by relying on what it knows about itself.

      --
      I used to have a better sig than this, but I got tired of it
    6. Re:Long healthy lives - maybe by tonyl · · Score: 1

      But that has nothing whatsoever to do with understanding the mechanics of cells or the chemistry of life.

      I also take issue with the greater argument (though unrelated to this thread). What does it mean to "understand yourself"? It can't mean that we can't map out major areas of responsibility in our brains, because we've already done that. It can't mean that we can't understand the chemistry that affects the brains operation, because we understand more and more of that every day.

      Nor is the mind a "closed system" in this context because we can and do examine all sorts of other minds. We know quite a bit about pyschology (how the complex organ reacts) from that: if Godel's theorem really had any bearing on this we wouldn't know squat about any of that, and quite a few folks would need to find other employment.

      So just what is it we supposedly cannot understand?

      But back to the chemistry of cells: my personal opinion is that defining "life" is exactly the same as defining "complicated": it's all chemistry and what you call living or not is just a matter of definition. No doubt that opinion will be sneered at, but I bet someday it will be generally accepted as correct.

      Again though, if your religious beliefs insist that there's something mysterious here, a "life force" that isn't related to chemistry, then there's nothing more to be said. We'll never understand life because it requires more than chemistry and physics. I don't believe that for a minute, but it's OK if someone else does - as long as that belief isn't used as a reason to prevent the advance of knowledge.

      --
      -- Tony Lawrence
    7. Re:Long healthy lives - maybe by davesag · · Score: 1
      if Godel's theorem really had any bearing on this we wouldn't know squat about any of that

      wrong. godel's theorem merely says that there would be more to know. - and waddayaknow... there is. no life force needed, just maths.

      --
      I used to have a better sig than this, but I got tired of it
    8. Re:Long healthy lives - maybe by crashnbur · · Score: 1
      I will be proved wrong when the technology is developed that allows me to "stick around".

      It kinda sucks that, in a way, my death is what will prove me right...

    9. Re:Long healthy lives - maybe by xutopia · · Score: 1
      don't think that technology fixes everything. It just allows us to do the same mistakes over and over again on a larger scale.

      Take for example 100 years ago next to no one had washing machines, dryers and dishwashers. Why did they have time to do crafts and other stuff? Why is it that we barely have free time and we have cars to drive us places faster than we could ever dream of going before?

      Fact is as soon as we are capable of doing something we do it and try to see what are the other limits of our stupidity. So instead of making the world better for our kids we simply provide tools for them to make bigger more blatent mistakes than us!

      Here kids, here is a bunch of technology that saves you time so you don't have to work as much as I did. I hope it gives you time to figure out the real meaning of life.

  75. Re:Yes!!! lets get relion fanatics out of medicine by dbrutus · · Score: 1

    Based on the limited experience of atheists in power (mostly 20th century communists who have the highest 'fellow citizens killed' totals and percentages ever) I'd say that there's ample real world reason to exhibit a bit of concern.

  76. Re:Yes!!! lets get relion fanatics out of medicine by dbrutus · · Score: 1

    I understood what he was saying but it makes it no better to argue that naziism was out of the christian tradition. There is a difference in kind between the nazi belief system and the christian belief system. I know that the Church intensively studies the German experience in the 30s to this day. Part of the results of that was a severe tightening of just war theory that we all saw on full display over the Iraq war where bishops played back seat driver to national leadership to an unprecedented extent very much because the German bishops of the time did not play back seat driver enough.

    As for the dichotomy between religious and moral, I would suggest that religious leaders are subject matter experts in morals and comprise a large majority of the people on the planet who professionally think about moral matters. The original post on this topic was about taking religious people out of moral supervisory roles regarding scientific experimentation. I don't deny that you *can* have non-religious moral standards, I do think that taking out the majority of professional moralists on the planet will inevitably reduce moral supervision of scientific experimentation which I hope you agree would be a bad thing.

  77. Yeah, they know. by twitter · · Score: 1
    Hopefully the people in charge realise that this is more than an attempt "to transcend embryo research ... [because] it's wrong".

    Yes, they understand all the good things you can do without killing babies now.

    --

    Friends don't help friends install M$ junk.

    1. Re:Yeah, they know. by Anonymous Coward · · Score: 0

      Yes, but not killing babies, that too, kills babies.

  78. Re:Yes!!! lets get relion fanatics out of medicine by Cappy+Red · · Score: 2, Insightful

    Dodging the godwin's law sidetrack...

    Science is not merely the realm for scientists to ask questions, they're merely the ones determined, talented, or able enough to put action to them. Everyone else in a society is also allowed to ask questions that the scientists can try to answer and that they must answer to. That society includes the "religious/moral types".

    It might have been prudent to cite one or two examples "of the reverse", when you asked for one of religious restraint in action for good. Nevertheless, I have none for either side. Rather, I say that I've found that history and especially the idle historian better remember the fantastically bad events than the quietly good ones. I myself am also an idle historian.

    And morality... do you scoff at all moral guidence in science or merely that from religion? Especially if it is the former, I hope you are neither a doctor mucking about with my insides nor a scientist mucking about with the Universe. Moral guidence, whether direct by personal belief, or indirect by considering the questions they raise, is what keeps us from destroying ourselves personally, publically, and scientifically.

    *honken quip about karma going up or down*

    --
    This is my sig. It's prescription, I swear. I need it for reading things... on the other side of things
  79. This reply is off topic by Anonymous Coward · · Score: 0

    I feel I've reached a new level in my geekiness. I actually understood and laughed at your sig. I'm going to go soak my head now.

    This post is made with the utmost lack of spine, in AC vision.

  80. Re:Yes!!! lets get relion fanatics out of medicine by I(rispee_I(reme · · Score: 1

    Based on the extensive of experience of deists in power, I'd say that atheists are the lesser of two evils. Unless one's opinions of theology have no bearing on how good a person one is...

  81. Re:Yes!!! lets get relion fanatics out of medicine by I(rispee_I(reme · · Score: 1

    arrgh, one too many "of"'s in the first sentence. forgot to preview.

  82. Re:Take That, Pope! ( a bit offtopic ) by Cackmobile · · Score: 1

    Excellent. I'm not religious and I don't believe in God. I believe that you should have a right to if you want to. I only wish more people who do beleive were like you. YOu see the corruption that is organised religion. Nice work.

    --
    -- Karma Karma Karma Karma, Karma Chameleon - Boy George
  83. Sweet by Cackmobile · · Score: 1

    I want 2 hearts and 4 lungs. Imagine how hard I could go. Of course i'd need a new liver as well.

    Its amazing the amount of responses this is getting.

    --
    -- Karma Karma Karma Karma, Karma Chameleon - Boy George
  84. Re:Yes!!! lets get relion fanatics out of medicine by dbrutus · · Score: 1

    Human beings of all ideologies can be rotten, brutal, evil and malicious. The relevant comparison in regimes is total deaths and percentage of your own population's death in my opinion. From memory, both figures are held by communism with the Soviets taking the total #s crown at 67 million and Cambodia taking the percentage crown at 1/3 of their own people in a few short years.

    By what metric were you judging the deists?

  85. Re:Yes!!! lets get relion fanatics out of medicine by I(rispee_I(reme · · Score: 1

    total slain. you gotta remember, the deists have been at it a while...

  86. stupidity is not a religion... by Anonymous Coward · · Score: 0

    ... religion is stupidity.

  87. Re:Yes!!! lets get relion fanatics out of medicine by dbrutus · · Score: 1

    The great spanish inquisition, a huge stain on the catholic church killed under 1000. If you're just guessing that the religious toll *must* be greater, guess again. The subject is serious enough that it deserves a true count. The total communist toll in one century is 100 million. That's a hell of a number over a very short period of time.

    On the side, you're using deists in a non-standard way. What exactly do you mean by it?

  88. Did you think this all the way through? by SquareOfS · · Score: 1
    Hopefully this kills off any remaining debate over cloning/killing babies and paves the way for real, theraputic research.

    Why on earth would the discovery of the "master gene" have any impact whatsoever on the debate over the moral status of stem cells derived from the destruction of embryos?

    The contention is that a human embryo, from the moment of conception, is a unique new human life, and deserves the full measure of respect and protection accorded to human life generally.

    (Sidebar: note that the contention is not that the embryo is a human person; personhood is fundamentally impossible to establish scientifically, since it is at bottom a philosophical and theological category. But an embryo is, inarguably, human life.)

    And yet those parties to the debate who support embyronic stem cell research persist in trotting out the most recent developments and extravagant promises of embryonic stem cell research as if they will determine the debate.

    Let me try to make it clear. Let us posit that embryonic stem cells will cure not just one, but every human disease; that they will erase poverty; usher in world peace; and make us all immortal.

    It is still irreducibly evil to profit from the deliberate destruction of a unique human life.

  89. Re:Yes!!! lets get relion fanatics out of medicine by I(rispee_I(reme · · Score: 1

    those who worship a deity.
    and i suppose your going by the catholic church's official records on the inquisition.

  90. Re:Yes!!! lets get relion fanatics out of medicine by I(rispee_I(reme · · Score: 1

    you're, rather.

  91. Re:Can we get a libertarian country first? by shaitand · · Score: 1

    None of them have rights that take precedence over the advancement of the human race as a whole. There issue settled, shows over, lets get back to work now.