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Weighing An Attogram

Roland Piquepaille writes "Researchers at Cornell University have reached a new level of precision by measuring objects with a mass of less than an attogram (10^-18 gram). They used a silicon cantilever oscillator to measure small dots of gold. But their real goal is to detect and identify viruses. The team also wants to reduce the size of the cantilever, extending the sensitivity well into the zeptogram (10^-21 gram) range. This summary contains more details and an image of a small gold dot resting on the silicon cantilever they used to achieve this breakthrough."

42 comments

  1. New tests for gravity. by G4from128k · · Score: 4, Interesting

    If they can use this to measure very small forces on very small objects, they might be able to construct some interesting tests of gravitational fields or of quintessence. We all think gravity changes with 1/r^2 and is irrespective of material composition, but do we really know that this rule works for ALL ranges of mass, distance, and material?

    Inquiring physicists want to know and this innovation could help them know it.

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    1. Re:New tests for gravity. by marcus · · Score: 5, Informative

      Your question reveals some confusion, perhaps produced by the wording of the article.

      They are not "weighing" anything. They are measuring the mass of the gold. These are two different things. Gravity is not involved in the latter.

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    2. Re:New tests for gravity. by QuantumFTL · · Score: 4, Informative

      If they can use this to measure very small forces on very small objects, they might be able to construct some interesting tests of gravitational fields or of quintessence.

      I don't really think that this technology in its current form can measure the forces on a particle that size. If you read the article, it is measuring the mass by measuring the resonant frequency, not measuring the forces present on the object.

      Yes I know that external forces can shift the frequency (due to nonlinearity) however I do not think that the precision of the device allows for measurement of such a weak effect.

      This has little to do, as another poster metioned, with other forces masking things at this small scale, but rather with the fundamental nature of the measuring device.

      Disclaimer: I'm a semester away from my BS in physics.

      Cheers,
      Justin

    3. Re:New tests for gravity. by mazarin5 · · Score: 1

      I think his experiment was in regards to interact between 'particles' on that small of a scale, now that we have a better means of 'seeing' them, but not necessarily how very small objects are affected by planetary forces.

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  2. How many... by dnahelix · · Score: 3, Interesting

    How many atoms of gold is that?
    Very fascinating! I love the picture.

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    1. Re:How many... by Patrik_AKA_RedX · · Score: 5, Informative

      Au: 197g/mol
      10E-18 / 197 = 5.076x10E-21 mol
      5.076x10E-21 x 6.022x10E23 = 3056.8 gold atoms.

    2. Re:How many... by Anonymous Coward · · Score: 2, Funny

      I was going to make a joke about atoms being atomic... ahh forget it.

    3. Re:How many... by dnahelix · · Score: 1

      that's cool. I'm guessing it should be rounded to an integer.

      Next question:
      How much is one gold atom worth?

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    4. Re:How many... by Rufus88 · · Score: 1

      3056.8 gold atoms

      So that's what? 3056 gold atoms and a europium atom?

    5. Re:How many... by Patrik_AKA_RedX · · Score: 1

      If you could isolate exactly one gold atom. I would say quite a lot.
      Really pure metals are quite expensive, and these are usualy only 99.9999% pure (give or take a nine). These are only used in labs, more common materials have a purity near 99% or worse.

    6. Re:How many... by Patrik_AKA_RedX · · Score: 3, Funny

      It means one atom is for only 80% part of the attogram. The other 20% is part of the attogram next to it.

      Or: 3056 gold atoms and a Gd atom (157.3ame ~80% of 197.0ame).

      Or: I broke one of the gold atoms, there quite fragile, you know.

    7. Re:How many... by Beryllium+Sphere(tm) · · Score: 3, Interesting

      Nostalgia department: there was one Asimov novel where a character is walking through a lab, and to convey a sense of wonder Asimov says the lab has a scale capable of weighing a billion atoms.

      I think it was one of the Caves of Steel series.

      Not only can we weigh things, we can identify them at infinitesimal quantities. There was a fact article in Analog about analytical chemistry. There are sensors today that can match the sensitivity of a dog's nose. That field has been advancing at the same explosive rate as computer performance has.

    8. Re:How many... by Muad'Dave · · Score: 1, Funny

      So can I have all of those extra fractional gold atoms? No one will miss 0.8 atoms out of 3056. I'll deposit them into my Swiss bank account, a la "Office Space".

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    9. Re:How many... by Anonymous Coward · · Score: 2, Insightful

      that's cool. I'm guessing it should be rounded to an integer.

      Actually... with his calculations it should be rounded to 3060 because there are only three significant figures in 197g/mol

      Obviously it gets the point across either way though.

    10. Re:How many... by Anonymous Coward · · Score: 0

      Oh yeah? Well, I have a scale capable of weighing a billion billion billion atoms!

  3. Tests will be difficult by Spamalamadingdong · · Score: 5, Insightful

    At that scale, influences like Van der Waals forces become far more powerful than gravity. Reading the pull of gravity with all the EM-related forces at work seems like a very, very difficult job.

  4. Ah, finally... by blate · · Score: 2, Funny

    ...finally a way to weigh my post-dot-com crash paycheck. :D

  5. Weight Via Chaos Theory by Doug+Dante · · Score: 3, Interesting

    I had this idea, which I've never implemented, of weighing items with extreme precision using a chaotic system. Since the chaotic system is sensitively dependent upon initial conditions, it should be possible to take measurements over a short period of time and work backwards mathematically to one of several possible initial weights. Eliminate those values that are not possible via other means (negative weights, far too heavy, far too light), and you should end up with an extremely accurate initial weight.

    I'm not sure that it would really work in practice, but I just thought it was a neat idea, and vaguely related to the authors' use of an oscilator.

    Perhaps if they were able to make the position of the oscilator at any time sensitively dependent on initial conditions, they could invent such a measurment tool (e.g. swing another weight in and out based on the position of the oscilator to slightly modify the local gravity in a nonmodal fashion that would make the oscilator sensitively dependent upon its weight and its inital position)

    My differential equations work is so far gone, I couldn't even begin to measure this mathematically anymore.

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    1. Re:Weight Via Chaos Theory by Tango42 · · Score: 1

      Isn't the whole point of a chaotic system that you *can't* work it backwards like that, because it's all too complicated?

    2. Re:Weight Via Chaos Theory by Baron_Yam · · Score: 4, Interesting

      Actually, this has already been done... though with optics. You take large numbers of measurements of 'nothing' and note the random static produced by the sensor. You can then subtract the average noise from the average of a large number of measurements of something and get an accuracy level theoretically beyond the ability of your instrument.

    3. Re:Weight Via Chaos Theory by Tango42 · · Score: 1

      But isn't random noise random, as the name suggests? (or at least chaotic, but without more information than it is realistically possible to get, it's as good as random) Minusing a random number will get you a random number. You can try and find some sort of systematic error and minus that, but pretending random error is systematic is going to cause problems, no?

    4. Re:Weight Via Chaos Theory by Baron_Yam · · Score: 1

      The idea is to average the noise over a large number of samplings, and subtract that from the average of a large number of samplings of whatever you are measuring.

      You don't subtract a single noise measurement from a single final measurement, which would double your error margin (you could have a perfect cancellation, or perfect addition).

    5. Re:Weight Via Chaos Theory by Anonymous Coward · · Score: 0

      I think you're talking about the "stochastic resonance" effect, which is quite fascinating...

    6. Re:Weight Via Chaos Theory by PD · · Score: 3, Informative

      The problem with this is that your system is chaotic. If you measure it one way, you can't tell how it's going to turn out. If you measure it the other way, you also can't tell how it began.

      And, the number of possibilities you have for a starting state would probably depend on just how sensitive your system is. If there's not many possibilities to choose from, then your system is probably insensitive enough to get an accurate measurement right up front.

      But it's a cool idea that would probably make a good gimmick in a sci-fi story.

  6. It will just grow back then... by Jru+Hym · · Score: 2, Funny
    But their real goal is to detect and identify viruses.

    A virus is what we doctors call very very small. So small in fact it could not possible have made off with an entire leg.

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  7. Attogram Huh Huh Huh by A55M0NKEY · · Score: 0, Funny
    So, how many sides does an attogram have? No, not a parralellogram, an attogram. No, I don't know what a perpendicugram is, but it sounds disgusting.

    How much would an attogram cost to send at Western Union? How many letters in an attogram anyway? Can I write normally or should I abbreviate with alotta yotta-yotta-yottas?

    Are attograhams good with marshmallows and chocolate?

    Tadum pum!

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  8. Great by BoomerSooner · · Score: 1, Funny

    Now I can figure out what smells so good in my crotch. Maybe I can get it in a bottle, make it stronger and spray it all over.

    I can see it now: Crotch in a Bottle, by Calvin Klein

  9. Re:Zeptogram? by cicadia · · Score: 5, Funny

    About 1.4x10^-11 microns/zL on the highway, 8x10^-12 or so in the city. Although I think that mileage is more commonly measured in zeptolitres per 100 Angstroms these days.

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  10. Re:Zeptogram? by Anonymous Coward · · Score: 0

    holy shit he actually calculated it...

  11. Zeptogram? by whistler36 · · Score: 3, Funny

    The zeptogram was never as popular as the grouchogram. People only use it because it's better looking.

  12. Re:Zeptogram? by Muhammar · · Score: 1

    Attogram: signature from renowned pilot

    {tasteless puns should be forbidden or forgiven by the government}

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  13. Identifying a virus by weight.. by Copious1 · · Score: 2, Funny

    Damn little bastards will become weight concious and go on a diet just to elude detection.

    1. Re:Identifying a virus by weight.. by Anonymous Coward · · Score: 0

      I don't know if you're joking or not...but if large scale detector/eradicators are installed in places like airports that might be exactly what happens.

  14. I can't be the only one thinking this.... by System.out.println() · · Score: 2, Funny

    But their real goal is to detect and identify viruses.

    Maybe they should license this technology to Microsoft?

  15. Not Easy by Rubyflame · · Score: 1

    Let me tell you, I'm very impressed. I tried doing this and I could never pull it off. No matter how many diets I tried and how many hours I spent on the treadmill, I could never get down to one attogram. So, to you dedicated researchers who managed to weigh an attogram... congratulations, and good luck in your modeling career.

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  16. Not just in optics by ControlFreal · · Score: 1

    A technique like the one you mention is very common in many measuring applications: it's called oversampling followed by lowpass filtering.

    Essentially, you're trading bandwidth for accuracy: the lower you make your lowpass bandwidth, the more you "average out" the noise, and the more accurate your measurement can become. However, the downside is that your bandwidth is very small, which causes your measuring time to be very large (you'll have to wait for your lowpass filter to complete at least a reasonable portion of its step-response).

    The above implies that there is a limit on low tight you can make your lowpass filter: the characteristic timescale of your lowpass filter must be larger than that of your actual phenomenon (not: noise) related signal, or else the process itself it "too fast" and the actual signal is also filtered out by your lowpass filter.

    Example: if you have a small amount of atoms that you want to weight, then having a too-large measuring time to obtain a 0.1% (or whatever) accuracy on the mass doesn't make sense if on the timescale of your measurement more than 0.1% of the material evaporates.

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  17. Re:Zeptogram? by Marijuana+al-Shehi · · Score: 1

    You mean Attagram, right? Only a sick bastard would log in to /. to make tasteless jokes about Septemb...oh wait!

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