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Superflu Being Brewed in the Lab

Genial Generalist writes "Superflu is being brewed in the lab, an article by Michael Le Page, describes some of the ongoing efforts to genetically modify the different strains of flu, specifically CDC modification of bird flu for the purpose of developing new vaccines."

18 of 332 comments (clear)

  1. Oh NO! Worldwide Outbreak!!! by dukeluke · · Score: 5, Funny

    Wasn't there a movie about this very topic not too long ago?...hmm...I believe it was dubbed Mission Impossible 2.

    Point being, haven't we learned any lessons from the movies?!

    Create super virus - (and hopefully the corresponding vaccine).
    Sell super virus to terrorists - (and act like it got stolen).
    Keep vaccine to sell to public when 'Outbreak' occurs (another good movie).

    I hope someone can understand the devastation that could arise should this truly happen!

    But, if 'Outbreak' does occur or 'Mission Impossible 2' then I'm getting out of the city and heading to the hills!

  2. Bosh by shystershep · · Score: 5, Interesting

    This make anyone else think of Stephen King's The Stand ?

    That said, I think the dangers of this are exaggerated. No doubt it would be a catastrophe if it were to escape the lab, but life is a lot more resilient than it is usually given credit for. Creating "a virus that could kill tens of millions if it got out of the lab" is a catchy line in an article (or a cheesy plot for a movie), but there is absolutely no basis for it. I think any benefit that comes from this sort of research far outweighs the hypothetical dangers.

    --
    The bigotry of the nonbeliever is for me nearly as funny as the bigotry of the believer. - Albert Einstein
    1. Re:Bosh by JASegler · · Score: 5, Interesting

      Guess you don't read much history do you.

      The Pandemic flu of 1918-1919 - 10-25% exposed died, 25-37 million victims. They think it was a mutated swine flu.

      Bubonic plague (bacteria actually but just to point out a very deadly NATURAL biological agent) - ~90% exposed died, ~137 million victims.

      When europeans came to the US the diseases they brought wiped out about 90% of the Native American population simply because they didn't have the resistances the Europeans had.

      So you think a genetically engineered flu like what was in The Stand isn't possible?
      That it couldn't have a kill rate as high as 90+%?

      Genetic engineering of this kind is far worse than radiation. At least radiation will decay and disappear in 50,000 years or so.

      Biological agents mutate and get stronger through the standard darwinian evolutionary processes.

      They only reason we got rid of smallpox was there was a global effort to vaccinate everyone on the planet for decades. Colds and flu strains are so numerous that we haven't been able to devise a way to get rid of the ones we know of..

      And they want to build super versions of something we can't irradicate now?

      To paraphase from memory The Stand:
      This is how the world ends, not with a bang but a wimper.

      -Jerry

  3. Dangerous research? by Anonymous Coward · · Score: 5, Insightful

    Some say that this sort of research is dangerous because of the risk of the virus escaping or being using in bioterrorism, and others that it's good science.

    Refusing to perform research does not preclude others from doing the same for evil purposes.

  4. Superflu by illuminata · · Score: 5, Funny

    Isn't that a bit superfluous?

    Oh snap, oooooh snap! Score one for the big I!

    --


    Until Slashdot fixes the funny modifier, use insightful or interesting. The poster knows your intentions.
  5. Fear psychosis? by aacool · · Score: 5, Interesting
    Stories of this nature tend to bring out alarmists, Cassandras, and 'the sky is falling' types as well as rationalists and 'it-couldnt-happen-here' types.

    The tendency of the human race to both improve it's awareness of the world while at the same time endangering itself has been the cause of grief and happiness.

    This though, seems to be of little benefit to anyone, unless it guarantees a cure for the common cold!

  6. old news ... by tazanator · · Score: 5, Interesting

    sorry but the USSR plan was nukes and a "virus cocktail". They would hit major cites with nukes and lay waste there, however the fields that made crops had to be saved (we ship most of the grain they live on to them). They planned to release biological weapons on the great plains, not just a little problem stuff but things like anthraz and small pox or malaria and eboloa. By mixing the virus it becomes harder to trace what antibody the hospital needs, and the next year they can vacinate some people against what was spread in the area to allow farming to resume, 2 winters later the dieases would have died.

    --
    I'm told you are what you eat, does that mean I can be you by tomorrow with some A1?
  7. shouldn't that be? by caino59 · · Score: 5, Funny

    1. Create ubervirus
    2. Create vaccine for said ubervirus
    3. ????
    4. Profit!

    sorry about that...

    1. Re:shouldn't that be? by Waffle+Iron · · Score: 5, Funny

      3. Release ubervirus

  8. How about 100 million? 200 million? by kcurtis · · Score: 5, Insightful

    The 1918 pandemic killed 30-40 million, about half of them otherwise healthy adults (as opposed to most flu's, which affect mostly the young and old).

    Given that the world population has more than tripled since then, and given the increases in world travel, a death toll of over 100 million would not be unlikely for a similar flu. I wouldn't be surprised if it went higher (with a similar strain to the 1918 flu).

    I heard on NPR a week or two ago, from an author who wrote about the 1918 pandemic, that in one instance a man boarded a trolley. Before the trolley got to the end of the line, the conductor and several passengers were dead.

    As far as the benefit outweighing the dangers, I agree. But I don't think the dangers are exaggerated.

    1. Re:How about 100 million? 200 million? by Sumocide · · Score: 5, Funny
      I heard on NPR a week or two ago, from an author who wrote about the 1918 pandemic, that in one instance a man boarded a trolley. Before the trolley got to the end of the line, the conductor and several passengers were dead.

      Probably because the trolley crashed, he just failed to mention that. Book sales and all.

    2. Re:How about 100 million? 200 million? by javatips · · Score: 5, Insightful

      I heard on NPR a week or two ago, from an author who wrote about the 1918 pandemic, that in one instance a man boarded a trolley. Before the trolley got to the end of the line, the conductor and several passengers were dead.

      How long was the journey in the trolley? I doubt it was long enought to cover the incubation period. So the people on the trolley were probably already sick and in an advance state of the infection.

      If a virus has a short incubation period and is very virulent (you die quickly) the less likely it will affect a large proportion of people.

      The more successfull virus are the one will long incubation period, take the virus that case AIDS for example.

  9. Human Evolution by Lord_Frederick · · Score: 5, Interesting

    I've read that human evolution has stopped, because modern medicine has eliminated most of the diseases that cause death prior to being mature enough to reproduce.

    If one of these superviruses was released, could it be viewed as a way of pushing along evolution, since only those strong enough and with the genetics to survive the virus would live to reproduce?

  10. This reminds me of some of the Animaniacs sketches by Darken_Everseek · · Score: 5, Interesting

    Good Idea: Studying naturally occuring flu viruses to learn how to prevent future pandemic outbreaks.

    Bad Idea: Deliberately creating new versions of the flu, to learn how to prevent future outbreaks.

    The frightening thought is that they aren't using the highest grade of quarantine level. I suppose though, when it does get out, they'll know how they made it, and theoretically, also how to fight it. At least until it mutates naturally.

  11. Nature's better at this than we are by stratjakt · · Score: 5, Insightful

    Movies generate a lot of fear of science, from the nuclear boogeyman who manifested as Attack of the 100 foot [animal] in the 50s and 60s, to the recent batch of nano-germ-megaflu series of movies, like 12 Monkeys, Outbreak, the Andromeda Strain, the Stand, etc..

    Fact is, noone brews up a killer virus like Mother Nature. There are thousands of strains of the flu, many fatal to a percentage of their victims.. HIV, Ebola, Smallpox, Anthrax, etc.. Lots of nasty shit out there. There's fecal coliforms on your toothbrush! Eww, I saw it on Mythbusters.

    Anyways, humanity survives. We survived the plague, we'll survive AIDS, we'll survive whatever Professor Peabody and his mad, mad test tubes come up with.

    After all, we don't know enough to cure the common cold, how could we know enough to create the perfect virus?

    --
    I don't need no instructions to know how to rock!!!!
  12. The problem with flu vaccines... by jeblucas · · Score: 5, Informative
    Flu vaccines--for the last several decades--are cultured in chicken eggs. The little eggs gets injected with flu virus, the virus replicates and the little liquid chicken produces antibodies, which are then sucked out and jabbed in Gramma's arm at the clinic. This works great. For swine flu.

    Avian flu, however, would likely kill the egg--Dead Eggs Produce No Antibodies, i.e. no vaccine. Luckily, it's more difficult for avian flu to make the species jump to humans in a virulent form, but the WHO, CDC, and other groups are scared to death some bird flu is going to figure this out soon and we'll be helpless in front of it. It's 1918 all over again.

    Don't get to cranky about these folks looking at ways to culture flu virii in something other than chickens--they're looking for answers.

    --
    blarg.
  13. Re: 1918 Pandemic- yes, it WAS that bad... by cbelt3 · · Score: 5, Informative

    My grandfather came down with the 1918 flu with his entire Army unit just before they shipped out to France. 2/3 of the unit died. These were young men at the peak of physical condition, but living in very close quarters. Most died literally overnight. He was hospitalized for a month, and fortunately, missed the war. And by the way, it was called "Spanish Flu". Most of the /. crowd is too damn young to remember the major pandemics of the 20th century (Spanish Flu, Polio, TB). Viruses can and will kill a hell of a lot of people in a hurry. Any nice theory to the opposite is obviously developed by people who failed to sudy or remember history. So far we've been damn lucky in the last 30 years. While I'm sure our luck will run out some time, deliberately coming up with an agent that will ENSURE megadeaths is the height of arrogance and stupidity.

  14. Virii and toxins by miketo · · Score: 5, Interesting

    IANAS, but if I recall correctly, the problem with biological agents like virii are that it's very difficult to create a highly contagious, high-mortality virus. Virii need a living host to reproduce, mutate, and pass on their modified genes to the descendants. Airborne virii need to be extremely hardy to survive outside their ideal breeding conditions (read: human host). And a virus that is so virulent it kills its host almost immediately won't live for very many more generations -- it's an unsuccessful mutation.

    That being said, it's still possible to balance all the factors so you have a fairly lethal virus, relatively contagious, that mutates quickly and successfully. It's just not as likely to end up as a Captain Tripps, or even an Ebola.

    Toxins, on the other hand, are better for short-term, near-instantaneous death, and are more likely to be "controllable" through judicious application. Again, there are contraindications such as method of application, weather, &tc. that would warrant not using them.

    The various death merchants will keep experimenting anyway, but it's nice to know that we're far more likely to be wiped out as a species by a giant asteroid than from a little critter built in a lab.