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ESA To Study Human Hibernation

colonist writes "The European Space Agency (ESA) plans to study human hibernation for long-duration space voyages (a la 'Alien', '2001'). Although 'practical hibernation mechanisms are at least a decade away', ESA researchers will make initial inquiries into DADLE (D-Ala,D-Leu-enkephalin), an opium-like drug that triggers hibernation in ground squirrels and human cells. Other subjects of interest include dobutamine, a drug that maintains muscle, and the Madagascan fat-tailed dwarf lemur, the only primate known to hibernate."

50 of 379 comments (clear)

  1. Alternative Idea by Anonymous Coward · · Score: 5, Funny

    Study making smarter bears capable of space travel! They already hibernate.

    1. Re:Alternative Idea by TopShelf · · Score: 4, Funny

      They could always use this bear as a test subject. He's already smarter than the average bear...

      --
      Stop by my site where I write about ERP systems & more
    2. Re:Alternative Idea by MindStalker · · Score: 5, Informative

      Not true. Generally in hybernation animals drop their heart rate significantly but it doesn't stop. Bears drop their heart rate from around 40-50 bpm to 8-12 bpm. Which is slighty above other animals, which often decrease to 4 bmp. But what makes bear hibernation unique is that its blood temperature only drops slightly, allowing it to wake up quickly.

      This is still hibernation.

    3. Re:Alternative Idea by Jim+Starx · · Score: 3, Informative

      The heart slows, it doesn't stop. If it stopped the animal would die; that is the definition of death, your heart stops. As for the definition of hibernation, it's a state of regulated hypothermia. That is why bears are not technically hibernating, their body temperature doesn't drop, so it is not considered a state of hypothermia. That is also the reason why they can be woken up easly. Heart rate can be increased fairly quickly, but body tempature is a much slower process.

      --
      The darkness... controls the music. The music... controls the soul.
    4. Re:Alternative Idea by Ralph+Wiggam · · Score: 4, Interesting

      That's cool that bears can maintain a moderate body temp for months without eating. Having a huge layer of fat is usefull. That could be a new diet. You take two weeks off of work, go into hibernation in some lab, and have your body consume your fat gut while you sleep.

      -B

  2. Women on long-term space flights? by garcia · · Score: 5, Funny

    Perhaps all long-journey astronauts should be women. There is a well known but seldom used gene present in women that causes immediate hibernation. It has been called the sex-gene. Once the word sex is mentioned the women immediately roll over and are asleep within seconds. This will continue until sex has not been mentioned for at least eight hours. If an automated speaker was constructed to force the sex-gene into operation every 6 or so hours the women should (in theory) remain unconscious.

    Yes my gf reads Slashdot. No, I am not getting any tonight.

    1. Re:Women on long-term space flights? by thebra · · Score: 5, Funny

      "There is a well known but seldom used gene present in women that causes immediate hibernation. It has been called the sex-gene. Once the word sex is mentioned the women immediately roll over and are asleep within seconds. This will continue until sex has not been mentioned for at least eight hours."

      This has been known to have side effects such as headaches.

    2. Re:Women on long-term space flights? by PrvtBurrito · · Score: 5, Funny

      Men, on the other hand have the opposite problem. They fall asleep immediately after sex. Interesting women fall asleep before sex, men fall asleep after sex. How was it we evolved again?

      --
      Laboratree - Scientific collaboration based on OpenSocial.
    3. Re:Women on long-term space flights? by HarveyBirdman · · Score: 5, Funny
      Perhaps all long-journey astronauts should be women.

      Controller 1: What happened?

      Controller 2: Jupiter Two has exploded!

      Controller 1: My God! What happened? Was there any telemetry?

      Controller 2: Just a snippet of transmission.

      Controller 1: Was it a distress call? What did you hear?

      Controller 2: I heard Commander Janice shout "You bitch!" and then Lt. Sally say something about clawing out eye. Then there was just ten second of hissing and spitting and howling.

      Controller 1: Oh no! They synchronized! The dreaded (looks around and whispers) full moon effect!

      Controller 2: I thought we solved that with those pills?

      Controller 1: Yes, but... (sighs) There were always unknows, and the Jupiter system... sixty-three moons!

      Controller 2: We were bloody fools!

      Controller 1: That's not funny, Bob.

      --
      --- Ban humanity.
    4. Re:Women on long-term space flights? by iphayd · · Score: 3, Insightful

      I know I am replying seriously to a joke, but...

      Women, with limited reproductive capability, have an instinct to protect themselves from unfit fathers.

      Men sleep after sex to counteract the ability to reproduce with another female almost immediately after copulation, hence keeping the couple intact longer.

      Of course society has come in and screwed us all up. Women now get pissed at us for sleeping, despite being a chemical reaction. Alcohol and Hollywood screw up what people consider healthy. ... and now back to your regularly scheduled topic.

    5. Re:Women on long-term space flights? by vidarh · · Score: 4, Insightful

      You must be incredibly bad in bed if you have that effect on women...

    6. Re:Women on long-term space flights? by MarsDefenseMinister · · Score: 3, Funny

      Houston, we have a headache.

      --
      No weapon in the arsenals of the world is so formidable as the will and moral courage of free men.-Ronald Reagan
    7. Re:Women on long-term space flights? by kgarcia · · Score: 4, Funny

      Here you go

  3. We must look to Teenagers... by BongoBen · · Score: 5, Funny

    for inspiration. They can sleep for days at a time.

    --
    The Dude abides.
  4. If it weren't for my daughter... by grasshoppa · · Score: 3, Interesting

    SIGN. ME. UP.

    Hell ya, I'd go hibernate, and very likely get paid for it. Can you say, "Test subject"?

    --
    Mod me down with all of your hatred and your journey towards the dark side will be complete!
    1. Re:If it weren't for my daughter... by Mr2cents · · Score: 3, Funny

      So here's the plan, grasshoppa: You find out what restaurant delivers pizza's to ESA, you get yourself a delivery job there and wait for a delivery for "I.C. Weener".

      --
      "It's too bad that stupidity isn't painful." - Anton LaVey
  5. Boring by Anonymous Coward · · Score: 3, Funny

    This is just the start of a decade long project. Wake me when they capable of making me sleep for a decade.

  6. Good job ESA by strictnein · · Score: 4, Interesting

    This type of research is the future of human space exploration, at least for the forseeable future. Sorry, but light speed, or anything near light speed, just isn't going to happen anytime soon.
    The only downside to this is that the space traveler may seem like the trip only lasted a short time period, when it in fact took 10 years. By the time he gets back home his family will have aged 20 years. It actually may be the closest we get to time travel as well (want to see the future? just hybernate for 100 years).

    1. Re:Good job ESA by mirko · · Score: 5, Insightful

      Not everybody is attached to their family and relatives, some might even appreciate a century-time shift in order to refresh their relations.

      --
      Trolling using another account since 2005.
    2. Re:Good job ESA by WormholeFiend · · Score: 4, Interesting

      By the time he gets back home his family will have aged 20 years. It actually may be the closest we get to time travel as well (want to see the future? just hybernate for 100 years).

      I don't think hibernation prevents aging...

    3. Re:Good job ESA by (54)T-Dub · · Score: 4, Informative
      Yes, but it seems to me that the article inferes that hibernation could slow the aging process.
      While talking about the drug DADLE
      It also seems to send cultures of human cells to sleep: the cells divide more slowly and their gene activity drops when the molecule is applied.
      --

      "I can not bring myself to believe that if knowledge presents danger, the solution is ignorance" - Isaac Asimov
    4. Re:Good job ESA by Monkey-Man2000 · · Score: 4, Interesting

      If that were true, it would be nice if this became so commonplace that you could "hibernate" every night for about 8 hours. Thereby, extending your lifespan by ~33%.

      --
      This post was generated by a Cadre of Uber Monkeys for Monkey-Man2000 (603495).
    5. Re:Good job ESA by ryanvm · · Score: 4, Funny

      Not everybody is attached to their family and relatives, some might even appreciate a century-time shift in order to refresh their relations.

      Fry, is that you?

    6. Re:Good job ESA by 2nd+Post! · · Score: 3, Insightful

      And you'd wake up tired, irritable, and cranky, seeing as you only had 3 hours of sleep!

    7. Re:Good job ESA by AKAImBatman · · Score: 4, Interesting

      Believe it or not, the speed of light is easy to "beat". It's just a problem of "beating it" in some usable fashion.

      For example, quantum tunneling allows a particle to travel faster than light for a mere instant of a second by stealing energy from nearby particles. In the end, however, it has to pay back the energy it used. This means that its net velocity never exceeded light speed.

      On the more macro level, there is a theory that wormholes could be used to circumvent light speed. Unfortunately, no one knows how to generate enough energy, or where to find the "exotic matter" to create them.

      Another (possibly even more credible) theory on FTL travel, is the Alcubierre Drive, often confused with the Star Trek notion of a "Warp Drive". Again, the core problem is that we have no idea where the energy for such a craft would come from.

      If none of this suits your fancy, then just load up on a few kilotons of Antimatter, and blast off toward the edge of the Universe at 1G of acceleration. Thanks to the dilation of space-time, you should be able to reach the edge of the known Universe in barely a few years time! Of course, there's this slight issue with Earth no longer existing by the time you got back...

      Good luck, intrepid space traveller!

    8. Re:Good job ESA by Abcd1234 · · Score: 3, Interesting

      It may, actually. Assuming such hibernation significantly reduces the basal metabolic rate, it can be surmised that lifespan would likely be extended. For example, the lifespan of lab rats have been greatly extended by placing them on an ultra-low-calorie diet, and it is theorized that this increase in lifespan is due to the decreased basal metabolic rate resulting from such a diet.

  7. An alternative solution. by mikael · · Score: 5, Funny

    ESA researchers will make initial inquiries into DADLE (D-Ala,D-Leu-enkephalin), an opium-like drug that triggers hibernation in ground squirrels and human cells. Other subjects of interest include dobutamine, a drug that maintains muscle, and the Madagascan fat-tailed dwarf lemur, the only primate known to hibernate."

    An alternative solution is to design a virtual environment simulator that will make ground squirrels and Madagascan fat-tailed dwarf lemurs believe they are jumping across tree branches, when in fact they are piloting an interstellar spaceships.

    --
    Vintage computer adverts: http://www.vintageadbrowser.com/computers-and-software-ads
    1. Re:An alternative solution. by BondHeadGuy · · Score: 5, Funny

      I can't believe I'm about to do this but...

      I, for one, welcome our new Madagascan fat-tailed dwarf lemur interstellar spaceship pilot masters.

      Ugh, I feel so dirty.

  8. Does cancer hibernate too? by Euphonious+Coward · · Score: 4, Interesting

    I wonder if tumors stop growing during hibernation. If they do, then everybody with (expected-) fatal cancer can just hibernate until there's a cure.

    Likewise aging...

    1. Re:Does cancer hibernate too? by jdmetz · · Score: 5, Informative

      That would be nice, but unfortunately hibernating is not the same as suspended animation. Hibernating animals still lose muscle mass and use energy. The metabolic rate decreases but does not stop in hibernation.

  9. Great idea! by NoMoreNicksLeft · · Score: 3, Funny

    As long as it's cheap enough I can afford it on my unemployment check, I believe it would be a good idea to simply hibernate for 20-25 years, and bypass the entire recession!

    Where can I buy some of this stuff?

  10. Oh yeah, that's comforting... by pergamon · · Score: 5, Funny

    "Don't worry sir, the device you're about to trust your life to is the result of years of research with the Madagascan fat-tailed dwarf lemur."

  11. I hope there going for basic science... by Retric · · Score: 5, Interesting

    Interesting but I think they're going to need to work out how to prevent bone loss if you're going to hibernate for a significant portion of the time in space. Anyway I hope there going for a basic science approach to the subject because if dobutamine maintains muscle mass during hibernation then it might also help with coma/bed-ridden patients.

  12. Atrophy by Short+Circuit · · Score: 5, Interesting

    Having someone sleep indefinately is only a matter of controlled sedatives. I imagine their biggest problem is going to be organ atrophy.

    If they solve that, then they'll have an extremely valuable spinoff technology that will help everyone from the temporarily wheelchair-bound to the hospitalized.

  13. OK, but will the ESA study how to build by panurge · · Score: 4, Funny
    Heuristic algorithmically programmed computers that don't decide to take over the mission? Science fiction precedent shows that being a hibernating crew member on a long voyage means you don't make it to the end of the movie. I guess we will need some of that old Russian technology with drum timers.

    Also, if the eventual mechanism is based on bear hibernation, how are the astronauts going to wake up and poo in the woods periodically?

    --
    Panurge has posted for the last time. Thanks for the positive moderations.
  14. I want it! by Sediyama · · Score: 3, Funny

    I want to hibernate and wake up in 5 years. So I can afford a Quake 3 compatible video card!

  15. Madagascan fat-tailed dwarf lemur by Esion+Modnar · · Score: 5, Funny

    Having a name like that is a survival mechanism. You see, when anybody's hunting them, by the time they say, "Hey, there's a Madagascan fat-tailed dwarf lemur!" it's gotten away clean.

    --

    They say the first thing to go is your penis. Well, it's either that or your brain. I forget which...
  16. Obscure Reference by jdavidb · · Score: 3, Funny

    The lid above rises and a light comes on. You are in a sponge-lined coffin. The only exit is out.

    The panel has 10 buttons: black, brown, red, orange, yellow, green, blue, purple, grey and white.

  17. Does cancer hibernate too? - Easier Surgury? by mykepredko · · Score: 4, Interesting

    I wondered the same thing - and going ahead with this, would it be easier to operate on somebody in hibernation?

    Would hibernation be part of a safer anesthetic protocol for surgury? Put the patient into hibernation with local pain killers rather than forcing them into unconsciousness?

    This could be a very useful spin-off of this technology and maybe be more important to humanity than facilitating very long duration space-flight.

    myke

    1. Re:Does cancer hibernate too? - Easier Surgury? by mykepredko · · Score: 3, Interesting

      And what, precisely, do you see the as philosophical difference between being drugged into hibernation and being drugged into unconsciousness?

      None - the current drugs used to "put somebody under" for surgury and lowering blood pressure/heart rate/respiration are dangerous and require constant monitoring of the patient. If the same function could be provide by a "hibernation drug", I presume that this would be easier on the patient and safer through the course of the surgury.

      myke

  18. Longhorn by angrist · · Score: 3, Funny

    Sounds like the perfect way to eliminate (subjectively) that pesky wait for Longhorn.....

  19. A Humble Suggestions for ESA by Dr.+Shim · · Score: 4, Funny

    Let me get this right, the ESA is creating an opium like drug to put people into hibernation on long space voyages.

    And this drug work's successfully on ground squirrels.

    Why not just send the squirrels into space, and skip humanity altogether?

    --
    People discover the meaning of life between getting piss drunk and the following hangover.
  20. I offer myself... by abkaiser · · Score: 5, Funny
    ...To test the "opium-like" drug. I'm that dedicated to scientific advance.

    Of course, the last time I heard something like that, it was from a bartender who suggested a drink and told me "it was as close to legal opium as you could get".

    So, one interesting night later, I have this advice: Stay away from Chartreuse.

  21. Just.. by the_mad_poster · · Score: 4, Funny

    ...send them to my cubicle. The second I enter it, all mental and physical functions shut down for hours.

    --
    Alito: A vote for Alito is a punch in the eye to put that bitch back in her place!
  22. Poor, poor lemurs by nagora · · Score: 3, Funny
    the Madagascan fat-tailed dwarf lemur, the only primate known to hibernate.

    A trait it is about to regret <sound of skull-saw starting up>

    TWW

    --
    "Encyclopedia" is to "Wikipedia" what "Library" is to "Some people at a bus stop"
  23. Oooh, and we can call it... by devphil · · Score: 5, Funny


    ...wait for it...

    Lemur's Game

    --
    You cannot apply a technological solution to a sociological problem. (Edwards' Law)
  24. Seasonal Affective Disorder by Beryllium+Sphere(tm) · · Score: 3, Interesting

    Some humans gain weight and lower activity when the days get shorter. Is it possible that we have a vestigial hibernation response already?

  25. Reasons the Article doesn't go into.... by Artifakt · · Score: 4, Interesting

    1. Radiation shielding on long term voyages seems to be a real bear of a problem for manned spaceflight to the planets. It might be feasable to put a bunch of shielding around a small compartment with a hybernaut where it wouldn't be feasable to shield all the working and sleeping areas for an awake astronaut.

    2. By extension, a 2001-like approach becomes workable - Put part of the crew into hybernation, rotate them in and out as needed. In 2001, this was supposed to be because the planetside geologists and such had little to do until Discovery was close to Jupiter, and then the security/paranoia factor kicked in. In the real case, a ship might rotate crew to even out radiation exposure, or put a crewman who was loosing bone mass faster than others into hybernation to protect his health.

    --
    Who is John Cabal?
  26. Solution by superdan2k · · Score: 3, Funny

    You know, the ESA doesn't have to spend a dime. All they have to do is drop someone into my job -- it keeps me slowed down, makes me want to sleep, and destroys my motivation.

    --
    blog |
  27. worthing saga by joeldg · · Score: 3, Interesting
    If you have ever read the worthing saga the ideas put forth in that book are amazing for what people might do if given the ability to suspend themselves while time goes by.
    Setting huge plans in motion while sleeping away, they end up with an entire section of the populace that tries to "live" as long as they possibly can. It is really an interesting take on how things like this could kind of get out of hand.


    Book Description

    It was a miracle of science that permitted human beings to live, if not forever, then for a long, long time. Some people, anyway. The rich, the powerful--they lived their lives at the rate of one year every ten. Somec created two societies: that of people who lived out their normal span and died, and those who slept away the decades, skipping over the intervening years and events. It allowed great plans to be put in motion. It allowed interstellar Empires to be built.

    It came near to destroying humanity.

    After a long, long time of decadence and stagnation, a few seed ships were sent out to save our species. They carried human embryos and supplies, and teaching robots, and one man. The Worthing Saga is the story of one of these men, Jason WOrthing, and the world he found for the seed he carried.

    Orson Scott Card is "a master of the art of storytelling" (Booklist), and The Worthing Saga is a story that only he could have written.