Human Hibernation on the Horizon?
Mincemeat.net writes "The BBC is reporting that scientists at University of Washington have successfully induced a state of extreme hibernation in mice. The mice suffered no ill effects. Naturally, testing in larger animals will ensue. Humans wouldn't necessarily appreciate the smell of hydrogen sulfide while being placed into suspended animation. However, the applications are numerous if the usage of similar techniques can be applied to us. Cancer treatment, delaying death from injuries, interplanetary expeditions top the lists of possibilities. While it's not a quick freeze, maybe Fry will be able to meet Bender after all."
Funny, Hydrogen Sulfide is a common enough contaminant in ground (well) water systems as well as a byproduct of oil refineries. It deprives the brain of oxygen and causes what IIRC is called "blowdown" or "knockdown" in oil refineries when people momentarily pass out.
6x9=42
...an instant coast-to-coast flight.... "Fifth Element" is coming true. :)
-Palal
Hibernation has been taking place in people since geeks took to their parents' basements.
Now that they've got that done, they can work on getting people to function on less sleep. I want to be a microsleeper.
I'm up for a little hibernation for space travel, but for medical aid? Aren't we already saving too many people who should be dead and thereby contributing greatly to world problems like overcrowding and world hunger and fun stuff?
Remember, open source is free as in speech, not free as in bear.
Here
I don't want to read
So I'll be alive when Duke Nukem Forever is finally released. :)
--- Grow a pair, liberals... stop letting the Republicans bully you!
why? oh why did it have to be THAT molecule?
Free electronics!
Wake me up when the Olson Twins are legal.
Wait, nevermind...
"The newly born animals are then whisked off for a quick run through a giant baking oven." --heard on Food Network
Injectable Hybernation. I'm sure this can't be abused in any way whatsoever.
"Finally, after being in a constant state of hibernation for the last fifty years, I am ready to greet the future!"
"Yeah...about that...we all kinda went in after you...so science and technology is about at the same point you left off."
"So I still have cancer?"
"Technically, yes. But hey, at least that asteroid never hit...right?"
One of the effects of hydrogen sulphide exposure is that is "paralyses" the sense of smell before a fatal dose is reached. This is normally very dangerous as people can think they have left the contaminated area while continuing in fact to breathe in more of the toxic gas.
So chances are you wouldn't have to put up with the smell too long, before you either stop smelling, die horribly or maybe just go into suspended animation.
Using these in prisons?
Seems a bit better then the death penalty, would also actually make those 600 year jail sentences mean something =)
One day you go to jail, 5 years later you wake up anew.
Remind anyone of Demolition Man? Good because it should!
Bender isn't really an alchoholic in the sense a human would be. In Futurama alcohol is fuel for robots, and they consider not drinking to be like alcoholism.
It's funny that Futurama has the technological development of two distinct and competing technologies for longevity. Fry gets frozen in the chrogenics centre, wakes up in the future and, a few episodes later, discovers that celebrities live on as brains in jars. If we had the technology to keep a human brain alive and kicking I'd much prefer that to getting my head lopped off and frozen in the hope that a sufficiently advanced technology will one day be able to revive me. Even if it ment I had to spend the rest of my days as a body-less paraplegic in a wheelchair I think I'd rather that than to die from cancer.
Hybernation offers a third technology. Instead of lopping off my head at the first sign of cancer, you could put my body into hybernation and keep my brain active with regular stimulation. Hopefully you could do it by jacking me into a video game. I could handle living in MxO, as long as it was on a non-hostile server. Maybe I could even earn a living as a member of the Live Events team.
How we know is more important than what we know.
Hey, I was frozen, I know what guy wants to hear first: the bathroom's that way.
</end of obligatory Futurama quote>
And what strikes me right off (because of my field) is, if a 'hibernation' state can be easily and mobily achieved, you could save a LOT of critical cases by slowing them down right at the point of injury or on the ambulance, maybe even before moving them. That would have a definite positive benefit for sure, though thinking about flying through space in slo-mo is a cool vision too, for sure. =)
-chitlenz
Imagination is the silver lining of Intelligence.
> Bender is an alcoholic robot.
...i am too.
Letter to my lawyer
Enclosed in this envelope is my account information. Please wake me up when I can afford a decent spaceship.
Thank you
PS. ZZZZZzzzzzzzz
The article and research paper note that they placed the mice in the hibernation state for six hours, without any long-term effects. Unfortunately, I can't find in either the article or paper if they tried longer hibernation periods. If they haven't, I suppose that's the next logical thing to try. Looking at their figures, it seems that the 6 hour mark is about when the body temperature finally finishes asymptoting down to the ambient temperature.
Anyways, here's the research abstract from Science:
H2S Induces a Suspended Animation-Like State in Mice
Eric Blackstone, Mike Morrison, Mark B. Roth
Mammals normally maintain their core body temperature (CBT) despite changes in environmental temperature. Exceptions to this norm include suspended animation-like states such as hibernation, torpor, and estivation. These states are all characterized by marked decreases in metabolic rate, followed by a loss of homeothermic control in which the animal's CBT approaches that of the environment. We report that hydrogen sulfide can induce a suspended animation-like state in a nonhibernating species, the house mouse (Mus musculus). This state is readily reversible and does not appear to harm the animal. This suggests the possibility of inducing suspended animation-like states for medical applications.
Really, I've done this. I hacked my deep freeze to cryogenically freeze me and let me awake in the year 2211. I set up a Unix server to run it all and made sure I had power available until then at least by having my power bill paid from an account into which I deposited $263. I figured the compounding interest over that time would more than pay for the power plus give me a nice nest egg when I awoke. Assuming they still used money in those days. I put myself to sleep on Februray 4th, 2003. Unfortunately I had forgotten to put out dog food for the time I was going to be asleep and poor old Turing (the dog) got a bit restless and he ended up pulling the power on that Unix box. Well, the freezer defrosted, the door popped open and I awoke. First thing I did was turn on the TV. MTV in fact and wow, everything was so different than before. I saw nothing I recognised. I was convinced I had awoken in my choosen time. ThenI looked at my watch and it was February 5th. 2003. Damn the fast moving and ever changing world of popular music.
From eating you alive? Metabolism is down to 10% of normal conditions and almost all of our enzymes have an optimum around 310 K (37 Degrees C). Immune cells won't be very active in hibernation (282 K, 11 degrees C), while some microorganisms flourish at that temperature. Just put a piece of cheese in your fridge, wait two months and take a look to see what the effects can be.
Actually there's probably already a couple of billion of them on your skin and completely sterilizing a human being (alive) is long from possible. Six hours of hibernation is one thing, but I wouldn't want to try this for more than a day.
Even if it's of no use for long-distance space travel, I think this would be still useful for shorter-distance space travel (say, to Mars). After all, it means you have to transport less food and water, and I think a slower metabolic rate also means that the effects of microgravity (like weakening of the bones) are slowed down.
The Tao of math: The numbers you can count are not the real numbers.
shithouse mice are resistant
I doubt that we will ever figure out - and I suspect that even if we did figure out we couldn't do much about it
Alright what's going on here.. several searches later I find the comments void of Bobba Fett jokes of any shape or size? What.. not even subtle nod towards carbonite, the fashionable substance that gave birth to advancements in stasis such as these?
Truly this is a dark day for Slashdotters everywhere...
Mice are also much smaller than humans (yes a statement of the obvious) and so their thermal mass is much slower - i.e. they cool down MUCH faster due to their increased surface area to mass ratio. I'll try to not become too enthusiastic until I see some larger animal studies - preferrably on cats (not dogs please - I like them) or also on a few of the weird looking guys who hang out at the gas station by my house.
..........FULL STOP.
As hibernation tech increases you can bet many will pay millions for it, and why not? All we need now is some megacorp to set up a freezing station on the moon to store all those human popsicles and they will be billionaires.
I doubt you would be so quick to condemn someone to death rather than hibernation if it was your life on the line.
at least airlines wont have to;
1. put up with idiotic customers
2. serve drinks and food
3. show entertainment
4. have good leg room
Just pack up em like cargo as tight as it can go.
Liberty freedom are no1, not dicks in suits.
Little nano-bots with little laser beams. Perfeerably resembling the classic blaster design from starwars. or perhaps tiny light sabres, although, the colladeral damage may be too great.
Fry: "You're a robot, why do you need to drink?"
;)
Bender: "I don't need to drink! I can quit any time I want!"
It's not as funny without the voices..
Its not so much our body warning us, it's the result of millions of years of change. The people who hated the smell more, were less likely to go near it, (or other rotting things that smell similar) and so didn't get the negative effects... the people (and creatures) who liked it more, didn't get to reproduce as often.
WANNAWIKI Wannawiki WannaWiki WANNAWIKI!
How about a religion of sorts for the wise. they sleep and tend-one-another in turns. The membership can be self-supporting with replacments chosen by the group by invitation.
every x years, a 'class is awoken', it is shown an explination of the last y years developments by the previous class (the previous class is then put into hibernation for a spell).
each class digests and reflects on humanities progress, problems etc. and issues reports, runs for offices, give grants etc etc etc.
right now, our insect-like-lifespans cause chaos. there is no incentive to plan long term, there is no incentive to build real solutions to real long-present problems.
maybe if we all lived longer (or my flight-of-fancy "Cult of the Wise") we would stop thinking about our personal pleasure more and start to think about how to gaurantee pleasure for all... and taking reward in eliminating war, famine, global-pollution etc etc.
or, we could fly off to other planets - hell i dont know.
I mean since mice can't talk how do they know how this affects their memories? The normal human brain cannot go without oxygen for 5 minutes, and while oxygen wouldn't be completely cut off from the brain, it would still be greatly reduced. I wonder if this would send the brain into a "skeleton system" type of environment where it keeps on only the bare essentials to survive and therefore shuts out memories. Humans breathe roughly 12 - 20 times per minute, if we apply the rate change of the mouse (1/12 it's normal rate) then humans would be breathing between 1 and 1.5 times a minute. I wonder if this would be enough oxygen for the brain to retain everything that it needs so when the person wakes up they can still perfrom their lives and jobs.
The Technomancer
"Men of lofty genius when they are doing the least work are most active."-
That is a solid reaming.
I get a cheque from my wife on thursday and deposit it that morning, and withdraw funds from that account. the cheque is funded by a paycheque that isn't actually present in the chequeing account until 12:01am friday.. I'm always amazed it works and they don't whine about it.
You should try taking your story to a local newspaper. Convince some journalist to write a good story about how this could screw over a single mom struggling to pay for milk even when she meticulously watches her spending!
you may have aged nothing while your twin brother or sister will have aged twenty, thirty, forty or however many years it is, depending on how long you were frozen. This will come to you as a profound shock, particularly if you didn't know you had a twin brother or sister.
Sorry it had to be done.
You have been warned.
*Hood on fire*
*Not good*
*EXR-H+ initaiates auto-extingush system, puts the flames out.*
*EXR-H+ releases Auto-Fix-It Unit SSE-3 which repairs the damage*
*EXR-H+ drives you to the nearest Holiday Inn Express*
It will drop you for a little more than "momentarily". H2S has the capacity to kill at less than 100ppm, depending on how long your exposure is. Yes, it will make you pass out -- but you might never wake up.
It's nasty stuff and all refineries, pipelines, and other oil/gas installations are trained about H2S and it's risks. Where H2S is present in the lines, you will see many of the technicians wearing portable H2S monitors.
(BTW, I sell H2S detectors for natural gas custody transfer points. Not the portable ones I spoke about but large scale one for pipeline intersections)
Energy consumption.
It's a moot point unless an alternative to our dependance on fossil fuels is found. Starvation will quickly solve the popluation problem in short order.
It's all about energy. If you have energy, nothing is a problem - period. If you don't have energy, EVERYTHING is a problem. We're past the point where a retreat to an agrarian life is possible without bloody revolution.
The only answer is new energy technologies - efficient fusion, improved fission, better solar, clean burning coal extraction and liquification, etc etc etc.
..don't panic
The uses are almost endless. Anyone can build a home H2S chamber and just shut themselves down for days at a time. I can envision a time when people are freed of the need to wait for anything. Spiderman 7 coming out in 15 days and you just can't wait? Hop in the chamber, dial it up for 14 days and 23 hours, and just "chill out".
The cool thing is that since metabolic activity cease, your cells would stop dividing, and therefore the aging process would cease as well. Opportunistic viruses would not multiply since they require cellular mitosis, and most bacteria would also take a nap.
I would, however, worry about anaerobic bacteria, especially the kind that thrive on sulfur gases; they'd literally eat you for lunch while you were out like a light. If even one of those suckers got inside, then when someone opened your chamber six months from now you'd be pretty much a skeleton with a mass of oozing, smelly residues--ewwwww!
I would also wonder about undigested food sitting in your stomach and small intestine for days or months, not to mention feces still in the colon. You want to move that stuff through before you shut down the system. On second thought I think I'll wait before trying this one out.
it's = "it is"; its = possessive. E.g., it's flapping its wings.
Comment removed based on user account deletion
After four years of daily exposure to HS during my time as a ammo "loader" in an Army artillery battery, my sense of smell is almost entirely gone. I can't smell anything noxious at all, and have to carefully control the conditions in order to be able pick up smells like perfume or coffee. So IMHO the olfactory nerve thing is very real.. Wish i could have hibernated through my foru years in the Army though...
No longer use my nose
The kittens run away from me and hide
Weird things between my toes
And people often think something has died.
I climb a lonely hill
On the Boulevard of Bad Hygiene
I frighten CowboyNeal
But he could learn to love it if he tried.
Something has died? Something has died.
Something has died? Something has...
My B.O.'s the only thing that walks beside me.
My B.O. makes strong men think of suiciding.
My Odor kills the flowers and the pine trees.
Smells like, something has died.
Arrgh ack, Arrgh ack, Arrgh ack, *Cough* *Cough*
Arrgh ack, Arrgh ack, Arrgh ack.
I'm walking down the line
diners flee the buffet so that's fine
so I can take my time
And eat onions, cabbage and... *sniff* something has died.
I can shower, fine.
Or I could on go slashdot tonight.
Closed window, pull the blinds.
But the neighbours think something has died.
Something has died? Something has died.
Something has died? Something has...
My B.O.'s clings to surfaces behind me
My B.O.'s beyond a mortal understanding
Sometimes they wish someone would put me in a... um...
Plastic bag, something has died.
Arrgh ack, Arrgh ack, Arrgh ack, *Cough* *Cough*
Arrgh ack, Arrgh ack, Arrgh ack.
Something has died? Something has...
I walk this empty street
On the Boulevard of Bad Hygiene
City evacuates
in it's pants and something has died.
My B.O. is worse than a Bush e-con-omy.
My B.O. gets UN weapons inspectors antsy.
My Odor could be casus beli if they could find me.
I think, Something has died.
from amiright.com
I appreciate the dangers of this particular chemical, but we won't necessarily use this chemical to achieve its effects in humans. If researchers figure out the process the chemical induces in organisms, they can synthesize safer methods.
Bring on the hibernation! Jupiter, here we come.
Hibernation would be stupid if you still die when you're 80... is there any research into whether or not it helps you to live longer?
brave new world was a dystopic nightmare future.
you did realize that right?
I'll just use my special getting high powers one more time...
If at all times the money you actually had in the bank was greater than the amounts withdrawn (was that $60 cash or a check? could be important) then they can't charge you for overdraft because it NEVER HAPPENED.a l/personal_cu.html> for contacts at US Bank. and try these for Kentucky's banking regulators:
IANAL, but I'm pretty shure deliberately failing to count a deposit when the funds were there (eigther imediately for cash, or as soon as the check clears for checks in most cases, check banking regs and/or a lawyer in the field for exact details) so they can then charge you shure looks like theft or fraud to me.
Also if they showed you a statement showing all the deposits and withdraws and still having a positive ballance then they go back re-do it to charge you I would expect that to be wrong as well.
I'd definately contact the governing body in your state and file a detailed complaint as well as climb as high up the chain of command with US Bank as you can, since they operate in multiple states I doubt they're doing that in many if any other branches and likely someone there is playing games (s)he can and would get fired for.
I once had a rent check bounce despite the banks own statement they issued me showing that I would have had $5.50 left after the check cleared, when I confronted them with that they could appologize fast enough and paid ALL the resulting fee's and wrote the management company I paid rent to a very sincere letter taking all the blame.
Banks are highly regulated and are not allowed to just willy nilly re-order the timing of deposits and withdraws to your detriment. Walk in and tell them you want it fixed post haste, do NOT show any doubt that you are in the right and make shure they know you know who to report thier misdeeds to.
You can try this page:<url:http://www.usbank.com/personal/sub_glob
Commissioner
Department of Financial Institutions
1025 Capitol Center Dr.
Suite 200
Frankfort KY 40601
502-573-3390
Toll free: 1-800-223-2579
Fax: 502-573-8787
Web site: www.dfi.state.ky.us
I suspect someone at that bank is telling you one thing and his out of town bosses another and pocketing the difference, or some other game that smells like embezzling. Just a hunch with no data other than what you've posted on moderngeek, but that is so screwed up I'd find gross incompetence the only other possible explanation.
Again if you confront them again be dead certain in your attitude, don't raise your voice, don't use fould language, just calmly and with total certaintity tell them they need to undoo all the innaproriate charges on your acount or you will have to notify thier superiors and the state banking regulators and possibly the federal athourities as you suspect a criminal activity.
Mycroft
https://signup.leagueoflegends.com/?ref=4c3ed6600b6ea