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Subjecting Yourself to Experimental Meds

ghostlibrary writes "Even while NIH is getting new ethics regs, patientINFORM is being evangelized as a way for ordinary citizens to look up experimental treatment online, in essence circumventing their doctor, and the FDA long ago tacitly approved this. /. debated Wikis in hospital. RSI fans track risky or untested procedures from the Typing Injury FAQ and Health-Hack covers IT-related self-help medicine. Laser-eye stuff is now mainstream and doesn't need a check beyond google. Any other sites out there for those willing to dictate their own medical course? Does this mean Internet users will become test subjects more than the usual college students and elderly?"

69 of 350 comments (clear)

  1. If nobody voulnteers no cures will be found by guildsolutions · · Score: 4, Interesting

    Its pretty obvious... If nobody vols for these medications, then the results will never be determined. Once we leave the earth we goto a better place above anyway, or so a lot of people tell me. Its a good thing to test experimental drugs...

    Just not on me.

    1. Re:If nobody voulnteers no cures will be found by PopeAlien · · Score: 3, Funny

      Its a good thing to test experimental drugs..

      Some of them are particularly good, I can taste the color green and I'm growing a fine pelt of electro-luminescent body hair!

    2. Re:If nobody voulnteers no cures will be found by Austerity+Empowers · · Score: 4, Interesting

      Provided the volunteers are informed of the risks of their choice by an independent medical expert. New-age/prayer treatments, or radical new drug treatments tend to sound attractive when argued by their supporters, but aren't always good choices.

      If I had a terminal condition I'd ideally like my doctor to lay out all my options, and explain them fully. This includes the conventional (but probably not so effective or pleasant), and the unconventional (and not have to worry that I or my family will sue him later). The reality is that traditional doctors can be a bit CYA, while the research doctors may be inclined to not tell me what I need to know. The laws and our social behavior are set up in such a way as to continue this situation.

      The next best option is to do my own research and run it by a couple conventional doctors and see how their answers disagree. It's not perfect but it's a step towards the ideal. This facility would seem to offer that, provided people who use it consult with an actual medical expert.

      Bottom line, if I am dying from a particularly untreatable form of cancer, I may be inclined to try something new. I just need to know what the options are, and what the odds are. Only I should be allowed to gamble with my life.

    3. Re:If nobody voulnteers no cures will be found by shish · · Score: 2, Funny

      Given the temperature of my CPU, I'd think those would be the directions to quite the opposite place...

      --
      I mod down anyone who says "I will be modded down for this", regardless of the rest of their comment
    4. Re:If nobody voulnteers no cures will be found by nmb3000 · · Score: 2, Funny
      You must be new here. Around Slashdot it would be more like this:
      goto aBetterPlace;
      Can't find label aBetterPlace at life line 4726421.
      --
      "What do you despise? By this are you truly known." --Princess Irulan, Manual of Muad'Dib
      /)
  2. sentence 1: wtf by Bootle · · Score: 5, Insightful

    Does that even remotely make any sense? Sure as hell doesn't to me...

    1. Re:sentence 1: wtf by shamowfski · · Score: 2, Insightful

      Nope. But I didn't think any of it made sense. I wish they made grammar check. It'd be this huge dude the just knocked the crap out of you for posting shit that doesn't make any sense.

    2. Re:sentence 1: wtf by hey! · · Score: 2, Informative

      Well, actually it does, it's just that the author tried to load so many ideas into it it's hard to disentangle them. Furthermore, the main point of the article is that there is a web site which allows people to access information on untested, nonconventional therapies, and that this is controversial for obvious reasons. Yet he leads of with a rather minor related point. The minor point he leads with is that NIH is working on regulations that might impact this kind of site. Since this is a minor side point, it doesn't actually lead anywhere, and the reader is confused as he scans the rest of the sentence and article in vain for evidence of the other shoe dropping.

      I actually went through the effort of reorganizing the article so it makes sense, but got down-modded for my trouble. Which goes to show that no good deed goes unpunished.

      --
      Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
  3. Ah yes by metlin · · Score: 2, Insightful


    This is just ripe for law-suits galore.

    Just wait and watch, until people figure out whom to sue to get the maximum out of. And then we can see this whole thing wither away...

    (Yes, I know. I'm quite cheerful on Mondays...)

    1. Re:Ah yes by stanleypane · · Score: 2, Insightful

      This is just a shot-in-the-dark, but I wouldn't be surprised if there is some wort of waiver that must be signed prior to beginning treatment/testing. I couldn't imagine these meds being gauranteed in any way, either.

      Hell, I live near Johns Hopkins in Baltimore and I can tell you they are *constantly* putting ads in the paper for experimental programs related to drug abuse and various other experimental treatments. Something tells me an institution as such has looked into the possible legal troubles they may encounter before doing anything like this.

  4. Be careful by thewiz · · Score: 5, Interesting

    My life was saved by an experiemntal drug. The doctors couldn't get my heart restarted after my third open-heart surgery via defibrillation or other methods. The anaesthesist was one of the doctors evaluating a new medication that showed promise for restarting hearts and used it on me. As you can tell, it worked.

    I've also been on the bad side of experimental drugs and have suffered thru some major side-effects. It's not a great feeling when the medication you are taking to eliminate pre-ventricular contractions makes you feel like you're living underwater.

    As for people volutarily subjecting themselves to experimental medications and treatment: TALK WITH YOUR DOCTOR FIRST! He knows your particular case better than any other doctor and can help you evaluate if you are a good candidate for the experimental treatment. It's a good thing that it's becoming easier to find out about available experimental treatments, but don't think it's going to be the "magic-bullet" cure until you find out more and talk with your doctor.

    --
    If "disco" means "I learn" in Latin, does "discothèque" mean "I learn technology"?
    1. Re:Be careful by Rude+Turnip · · Score: 4, Funny

      "As you can tell, it worked."

      That, or you're a zombie.

    2. Re:Be careful by guildsolutions · · Score: 2, Interesting

      My mothers life was also saved in such a way, it was nearly 16 years ago and she's still living today. My father and our family lawyer signed tons and tons of papers releasing the hospital/doctors from malpractice and other legalities... But they finally got her heart started and... Thankfully, she's still with us today... 16 years later.

      As I said above, these drugs have to be tested on someone. When the time comes to say.. "Your dead.. but we can try this and see if you will be alive.. well, Lets try it!"

      I would rather be alive than dead anyday, even if I do go to the place above, and I still have my mother here today.

    3. Re:Be careful by SoTuA · · Score: 2, Funny
      As you can tell, it worked.

      Oh really? You expect us to believe that you are alive *just* because you posted on slashdot? Ha!

      I'm afraid we'll need further proof...

    4. Re:Be careful by Alzheimers · · Score: 2, Funny

      This conversation held not long after:

      Paramedic #1: You have no pulse, your blood pressure's zero-over-zero, you have no pupillary response, no reflexes and your temperature is 70 degrees.
      Thewiz: Well, what does that mean?
      Paramedic #1: Well, it's a puzzle because, technically, you're not alive. Except you're conscious, so we don't know what it means.
      Thewiz: Are you saying we're dead?
      Paramedic #2: Well, let's not jump to conclusions.
      Thewiz: Are you saying we're dead?
      Paramedic #2: No conclusions.
      Paramedic #1: Obviously I didn't mean you were really dead. Dead people don't move around and talk.

    5. Re:Be careful by DrStrange66 · · Score: 2, Funny

      My life was saved by an experiemntal drug. The doctors couldn't get my heart restarted after my third open-heart surgery via defibrillation or other methods. The anaesthesist was one of the doctors evaluating a new medication that showed promise for restarting hearts and used it on me. As you can tell, it worked.

      By any chance was this medicine from a company called the Umbrella Corporation?

  5. No. by shamowfski · · Score: 2, Funny

    Last time I checked, my computer could not innoculate me.

  6. Its your life by Ars-Fartsica · · Score: 3, Insightful

    If you understand the risks, side-effects, and possible benefits, anyone who is mentally fit should be able to insert whatever materials they wish into their own body presuming no perceived liabilities to others (which would preclude crack, PCP, etc).

    1. Re:Its your life by Knara · · Score: 3, Insightful

      How exactly are "crack, PCP, etc" automatically liabilities to others?

    2. Re:Its your life by garcia · · Score: 2, Insightful

      It's not "automatic" with anything but a good majority of users of any addictive, mood altering, substance (i.e. alcohol, crack, PCP, etc) become a liability in some way.

    3. Re:Its your life by Rei · · Score: 3, Insightful

      While in a general sense I completely agree with you (and have even taken that route myself and assisted others with it), I would clarify that your "no perceived liabilties to others" addendum precludes things like antibiotics and antivirals. If you use them wrong you can turn your body into a breeding ground for "superbugs", which can then go on to cause immense harm.

      --
      Freeze Ray. Tell your friends.
    4. Re:Its your life by dustman · · Score: 2, Interesting

      How exactly are "crack, PCP, etc" automatically liabilities to others?

      In exactly the same way drinking and driving is a liability to others.

      You're not going to run down some schoolkids every time you drive after a sixpack, and you're not going to kill random strangers every time you get juiced on PCP, but you're statistically an unacceptable liability.

    5. Re:Its your life by stanleypane · · Score: 4, Interesting

      No medicinal value? Cocaine was once used as a local anesthetic. What do you think helped spur the creation of synthetic drugs such as novacaine or lidocaine?

      Ditto for PCP. It was originally procuded as an anesthetic for humans later used by veterinarians. Now, neither uses them because of their potential for abuse. Ever heard of Ketamine? Another popular anesthetic used by vets. It is in the same family of drugs as PCP.

    6. Re:Its your life by gowen · · Score: 2, Insightful
      you're not going to kill random strangers every time you get juiced on PCP, but you're statistically an unacceptable liability.
      What you say applies to drink without the driving. Drunk people are much more likely to engage in violent, anti-social behaviour than sober people. But that's a piss-poor reason for prohibiting booze (or PCP), because it indiscriminately punishes the well behaved and the ill-behaved user equally.

      I bet you $100 that more people are killed by drunks than PCP users, even after you excludie drink-related traffic accidents.
      --
      Athletic Scholarships to universities make as much sense as academic scholarships to sports teams.
    7. Re:Its your life by InfiniteWisdom · · Score: 2, Funny

      Don't worry. I've got mod points. I've got you covered.

    8. Re:Its your life by Frank+T.+Lofaro+Jr. · · Score: 2, Interesting

      Most people that need experimental drugs are in no shape to be driving a truck.

      Heck, even if one was on such a drug and physically capable, they wouldn't pass the medical requirements. You need a certain level of health to be allowed to drive a truck.

      --
      Just because it CAN be done, doesn't mean it should!
    9. Re:Its your life by vorpal22 · · Score: 3, Interesting

      The reason people's freedoms in this regard are limited, is because their actions, over time, inflict a financial burden upon society that the individual does not pay for.

      I disagree with your claim for a number of reasons.

      First off, if you look around at a historical account of the formation on the war on drugs, you'll see that it stems largely from the general racism towards the Chinese, the African Americans, and the Mexicans during the early to mid 20th century.

      Secondly, many activities that we partake in daily, over time, inflict a far, far more disastrous financial burden upon society that the individual does not pay for. Examples? Alcohol, tobacco, excessive unhealthy / fast food consumption, lack of exercise, etc.

      Am I free to refuse to contribute my tax / insurance dollars towards your health care because I disapprove of your lifestyle? If I don't think your exercise regime is sufficient, or I feel that your diet doesn't meet my standards of healthiness, am I free to request that you pay your own hospital bills?

      I daily engage in a good 40 minutes of cardiovascular exercise. I eat naturally - opting to completely avoid unhealthy fats and artificial ingredients - and organically, when feasible. I also choose to use certain drugs, usually illegally, because I've spent man-months researching psychopharmacology, neuropharmacology, ethnobotany, etc. and feel that the substances that I do use offer far more benefits than risks. My doctor is well aware of my drug consumption and condones it, feeling that it is probably far more beneficial in terms of relaxation, spiritual growth, etc. than it is detrimental.

    10. Re:Its your life by Qzukk · · Score: 2, Funny

      angle dust

      I tried snorting that angle dust once. You have to be careful, the good stuff is nothing but right angles. If you get the cheap shit, you end up with nothing but obtuse angles that don't even fit in your nose, or worse, acute angles that scratch and sting like hell.

      --
      If I have been able to see further than others, it is because I bought a pair of binoculars.
    11. Re:Its your life by hey! · · Score: 2, Informative

      Well, sure, but you're not really addressing the original poster's point, are you? Crack is not used topically, it is smoked. Furthermore, it provides an intense high that wears of extremely quickly. Therefore crack has no practical medicinal value as an anesthetic.

      Likewise it is true that PCP was pioneered as an anesthetic, but it was never very useful and has been supplanted by ketamine, which as you pointed out is related, but is clinically superior. Therefore PCP has no medicinal value given that ketamine is available, in much the same way heroin is not useful given that morphine is available.

      I don't necessarily endorse the original poster's opinion, in fact I'm skeptical. I think this thread points to why: people are very apt to jump to unwarranted conclusions. Cocaine was once used as an anesthetic, therefore crack is potentially medically useful. PCP is similar to ketamine chemically and pharmacologically, therefore it can be used the same way. Heroin is converted to morphine in the brain, so it can be used like morphine. None of these statements logically follow, but they're sure to convince somebody who sufficiently wants to believe.

      If you make the argument from a purely philosophically libertarian viewpoint, I suppose it can't be argued with. If the government has no position in protecting people from their own stupidity, then so be it. However in that case, allowing people to muck around with powerful drugs is not something that you do to promote health and physical well being, it's a matter of liberty.

      --
      Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
    12. Re:Its your life by Dread_ed · · Score: 2, Funny

      "Cocaine was once used as a local anesthetic

      I can vouch for the use of cocaine as a local anesthetic by doctors. My niece was bitten by a dog on the mouth a few years ago and they uesd it to numb her face while they did the initial repairs. Not sure about what was used by the plastic surgeon in the later operations.

      As for PCP it did have a recent resurgence of use experimentally for treatment of stroke patients. Most stroke patients have the majority of their brain destruction caused by the production of glutamic acid. It is produced in large quantities when oxygen is REINTRODUCED into the brain after the stroke happens. PCP prevents this glutamic acid production, but it was considered unsuitable for use in the general population for obvius reasons. Other drugs have now been created that will eliminate the symptoms without making the patient see angry purple midgets.

      --
      When the only tool you have is a claw hammer every problem starts to look like the back of someone's skull.
  7. WTF on the challenges? by PornMaster · · Score: 4, Interesting

    I'm as cynical as the next guy, but how the fuck can someone challenge the publishing of information as violating the Freedom of Information Act?

    1. Re:WTF on the challenges? by benhocking · · Score: 2, Informative

      It took me a while to figure out that you were referring to:

      Meanwhile, the APS/AAI statements cite other federal policies and regulations the NIH proposal seemingly violates, including the Freedom of Information Act and an Office of Management and Budget circular that says the NIH must perform a "cost comparison study."
      from the evangelized link in the original story.

      To address your question, I think at least one site lost information in paraphrasing. APS states "While this outcome arguably could be defeated by reliance on FOIA Exemption Four, 5 U.S.C. [section] 552(b)(4)...". And the FOIA shows that this exemption is "trade secrets and commercial or financial information obtained from a person and privileged or confidential". However, this does not mean that this information cannot be published (as far as I can tell - IANAL), merely that it doesn't have to be published. However, I think that the previously mentioned link has misrepresented the APS position on this. (I'm not saying I agree with the APS, merely that I don't believe they are using the FOIA to justify blocking the information, merely saying that the FOIA does not forbid blocking the information.)

      --
      Ben Hocking
      Need a professional organizer?
  8. Day Job: Lab Rat by RobertB-DC · · Score: 5, Interesting
    Moderately Off-Topic Anecdote time!

    One of my favorite unknown alt.country singers, Slaid Cleaves, tells the story of his day job: lab rat for experimental medicines at a center in Austin, Texas.
    I take drugs for a living. I'm a human guinea pig. A lab rat. A medical research volunteer. Pharmaco International pays me to stay in their facility for about $100 a day. Some studies only last a couple of days. Some are comprised of several weekend stays. Right now I'm in the middle of a long term study. 22 days. We are in the facility for the entire time, except for a few 20 minute walks around the building for fresh air. No visitors. No outside food. Hospital type meals are provided, along with newspapers, movies, pay phones and a clip board that tells us where to be and when for certain "procedures."
    The rest of the story (including the lab's phone number, if you're interested) can be found at Slaid Cleaves' web site.
    --
    Stressed? Me? Of course not. Stress is what a rubber band feels before it breaks, silly.
    1. Re:Day Job: Lab Rat by TomSawyer · · Score: 2, Funny
      The rest of the story (including the lab's phone number, if you're interested) can be found at Slaid Cleaves' web site.

      Wait, those weren't alt.country song lyrics? I was coming up with a little tune in my head to go along with it while reading.

      --
      If you disagree then it must be overrated, redundant or trolling.
  9. I'd argue the opposite.. by Quickfry · · Score: 2, Interesting

    Why would Internet users subject themselves this type of thing more than others? If we have the ability to find out about the experimental meds online, we'd know better what we were dealing with, and know enough not to subject ourselves unnecessarily.

  10. what??? by demonbug · · Score: 3, Insightful
    patientINFORM is being evangelized as a way for ordinary citizens to look up experimental treatment online, in essence circumventing their doctor


    How is gathering infromation on experimental treatments "circumventing their doctor"? It seems to me that it is better to be informed about potential or experimental treatments for an ailment you are suffering from - if you are interested, bring it up with your doctor. And no, that doesn't mean you should TELL your doctor you want this or that treatment; the idea is to inform yourself, not attempt to replace the years of training and practice a doctor has. Seems like a non-issue to me.

  11. Finger joints by Colin+Smith · · Score: 3, Interesting

    After typing all day every day for, hmm, decades now my finger joints get painful. I've found that glucosamine and chondroitin supplements work wonders. They take a couple of days to kick in but no pain. IIRC they act by improving the cushioning the joint better and allowing it to heal.

    --
    Deleted
    1. Re:Finger joints by Anonymous Coward · · Score: 2, Funny

      I find that C2H5OH helpsh the mosht.

  12. Democratization of Information by under_score · · Score: 2, Insightful

    In general, I really like this sort of development. It is the way the alternative health scene has worked for years (although, of course, only recently through the internet). There is a lot to be said for anecdotal evidence - but of course it is also dangerous. Many people feel under or mal-served by the medical establishment. Why not do one's best to bypass it?

    Personally, I have a strong science background so I feel slightly confident about investigating remedies on my own. I do fear for people with poor educations though. That's one thing that the web is good for - it helps people self-educate.

  13. /. abbreviation by kevin_conaway · · Score: 4, Insightful

    ...and the FDA long ago the tacitly approved this. /. debated...

    Can we please refrain from starting sentences with the /. abbreviation?

    1. Re:/. abbreviation by guitaristx · · Score: 2, Interesting

      Are you referring to your own subject?

      --
      I pity the foo that isn't metasyntactic
  14. Trust in Medical Professionals by lukewarmfusion · · Score: 4, Insightful

    Doctors are like help desk technicians - you come to them with a problem, they have tests they can perform, and in the end they try to help you fix whatever's ailing you. But also like a tech, doctors are not always perfect - they have to make educated guesses about the problem and can definitely make mistakes. (The analogy continues, but it's important to realize the difference in necessary education before a person becomes a doctor. The risks of a PC crash are nothing compared to an allergic reaction that results in death.)

    Now just like calling a computer tech, your visit to the doctor may not be that fruitful. It is possible that you will discover something your physician doesn't - after all, it's your body. In many cases, the doctor may not be willing to spend hours of research time finding a possible treatment for you. It's not surprising that you're willing to spend those hours on Google or other resources.

    What I'd suggest is that you do your research and present your findings to your doctor. Work with him or her to approach these findings from an objective (try) standpoint and leave your emotions at the door. If your doctor will not work with you and you believe that one of these treatments may be successful, find another doctor who will be more receptive.

    A few months ago, I went to the doctor with what I feared to be bronchitis or pneumonia. He told me I had the flu and prescribed a couple of things. I was skeptical of his anti-viral Rx, and when I went to get them filled the pharmacist told me that these drugs were only supposed to be prescribed on the first or second day of symptoms (I was in my fourth). I felt like the doctor (not my regular, but someone filling in) just gave me something to get me to leave. I did some research, and sure enough, there was no reason he should have prescribed those pills other than to mollify me.

    Like telling a user "run a defrag."

    1. Re:Trust in Medical Professionals by justforaday · · Score: 2, Insightful

      It is possible that you will discover something your physician doesn't - after all, it's your body.

      While I agree with everything you said in your post, you shouldn't forget that the doctor may also find something that you would never be able to diagnose (in your analogy think of a keylogger that AdAware or SpyBot don't detect). Just because you found something online that you think may help you, you should always remember that the doctors are the experts in the field. And as always, you should get a second opinion for anything really important.

      --
      I'll turn into a supernova and burn up everything. Well I'll turn into a black little hole and you'll turn into string.
    2. Re:Trust in Medical Professionals by lukewarmfusion · · Score: 2, Insightful

      Very true. I would never recommend that someone take their healthcare entirely into their own hands (auto-surgical procedures are messy). :)

      Always get a second opinion if you don't feel your doctor is giving you the best care you can get. Of course, there are folks out there that simply refuse to believe what doctors tell them so they end up hurting or deluding themselves.

  15. Experimental drugs... by TripMaster+Monkey · · Score: 3, Funny


    I've tried plenty in my time...didn't know you could get paid for doing so...

    ^_^

    --
    ____

    ~ |rip/\/\aster /\/\onkey

  16. Experiment test subject by LarsWestergren · · Score: 3, Interesting

    I volunteered as a test subject a couple of years ago, several times. Partly because of the money (though you didn't get that much), but also, I guess, for the thrill of it (I wouldn't do it today).

    Most of the experiments were totally harmless, but I have a couple of good horror stories. One experiment was a medicine for lowering blood pressure. It worked let me tell you, I almost passed out when running up some stairs the second day, and I'm normally fairly fit. It also contained beta-blockers, which turned out to give me horrible nightmares. Serveral nights I dreamt of being paralyzed, drowning while being tied up, buried alive etc. When waking up from the nightmares I was panicking, but I had problems moving. My body felt sluggish, and my heart was punding very hard but slow, though it *felt* like it should be racing.

    A lasting positive effects of the experiments was that I lost my phobia of needles and blood after giving blood samples once every hour for 24 hours.

    --

    Being bitter is drinking poison and hoping someone else will die

  17. Can you dictate the treament to your doctor? by l2718 · · Score: 2, Informative

    On the news in England: a man afflicted with a degenerative brain condition has won a court ruling last year that will force doctors to give him water and food even if he cannot ask for it possibly a reaction to the then-ongoing Schiavo case in the US. Doctors are protesting that this "undamentally altered the nature of doctor / patient relationships and was not in the best interests of the patient."

    I have not read the ruling, but I think it should be self-evident that if this guy wants to be sustained even when he can't ask for it, this should be done.

    Doctors claim the ruling means they "would have to provide treatment which they knew would be of no benefit or could even be harmful", which is why I am making the post here. Indeed patients should not be able to force any particular doctor to give them treatment that, in his judgement, is medically unnecceary. Of course, they should be free to find a doctor who agrees with their choice of treatment. Of course, this can be bad for them, as the heading story points out, but it is their problem.

    That said, I fail to see how giving someone food and water can be "harmful". It may be "of no benefit" only to the extent that the person's life is of no benefit, which is not for the doctor to judge especially when the patient has spoken on the matter.

  18. All medications are experimental forever by G4from128k · · Score: 4, Insightful
    All medications are experimental for three fundamental reasons:
    1. Clinic research is not statistically adequate: testing a medication on 10,000 people will not catch adverse side effects that kill 1-in-20,000 (e.g., kill 1,500 per year when 30 million peapl take the drug). Aspirin given to millions of children for more than 100 years before discovering Reyes syndrome.
    2. Genetic variations: People aren't genetically uniform. A drug that tests safe and effective on Chinese patients may kill Caucasians (and the Chinese and Caucasians are hardly genetically uniform). For childhood leukimia, there are currently 3 different drugs and they use genetic testing to determine which one to use (the wrong one is lethal).
    3. Environmental factors: The other substances that you ingest affect drug behavior. Two different drugs may be metabolized via that same pathway and thus if you take both, it slows the the processing of the drug (may increase or decrease the drug's effects). Foods also affect the results. For example., grapefruit deactivates certain digestive enzymes that otherwise limit absorption of some drugs (e.g., you get a higher dose of the medicine if you take it with grapefruit juice).
    The point is that there's rarely enough data and too many genetic and environmental variations to judge all the effects. No medicine is ever proven safe. At best, you can create statistical confidence estimates on the likelihood of adverse reactions, but the genetic and environmental factors make these hard to do.
    --
    Two wrongs don't make a right, but three lefts do.
  19. Desperation? by catdevnull · · Score: 2, Interesting

    I suppose if there's an experimental drug out there that needs testing and it's aimed at my particular affliction/malady, I'm game for it if the docs can't do much for it with exhisting medicine or techniques. [And the side effects aren't worst than the disease--such as 'anal leakage'].

    But, then again, there ain't no cure for the summertime blues.

    --

    I might know what I'm talkin' about, but then again, this is Slashdot...
  20. What is a doctor? by qualico · · Score: 4, Interesting

    Next time your in a doctor's office, ask to see their drug indications guide.
    You should be given a thick manual with pages of fine print on all the available drugs and the interactions/warnings of each.

    The scary part is that it will be choked full of advertising.
    For example; notice the thick tabbed glossy insert for "Viagra".

    This may not be as fraudulent as this:
    http://www.whistleblowerfirm.com/pharmaceutical-fr aud/

    However, it does beg the question, "What is a doctor?"
    If they are being swayed by advertising and free samples, than they are nothing more than a sales agent.

    That be said, there are no doubt a class of doctors who see beyond this garbage and choose to educate themselves to offer an unbiased and professional service for their clients.

    Good on ya, if you have found the later, otherwise you might as well just subject yourself to experimental meds.

  21. patient directed medicine by Anonymous Coward · · Score: 5, Insightful

    [ Disclaimer: I come from a family of MDs, so am probably unusually sympathetic to doctors ]

    There is a general problem with medicine in the US, and this story is part of it. The medical system considers us "patients" who are to be taken care of. But the insurance system considers us "customers", who have to manage our own health care, and figure out how it will be paid for.

    Here's my latest example: I have good reason to suspect I have high LP-a, a condition that can be detected with a simple, inexpensive blood test. The results are easy to interpret, but the test is not standard procedure, especially for someone my age (young).

    The local hospital does the test for $30. My insurance won't cover this test, so it is going to be out of pocket for me. BUT, the hospital won't do the test without a doctor's prescription (read: permission). They say this is so that it gets "billed to your insurance" correctly (even when I say that I am paying out of pocket).

    I can go find some doctor (I don't have a regular doctor), pay a few hundred dollars (insurance won't cover this visit), and explain in gory detail why I want this specific test, hope that they don't think I am kook and give me the prescription. Then I pay the $30.

    The kicker is that the hospital still won't give me the results. Instead, they will only send them to the doctor, requiring a second visit, and more money I don't have.

    So how does this make sense:
    - A test is being done on me
    - But doctor must consent (no mention anywhere of my own consent, by the way)
    - The results, in medical file, are kept hidden from me
    - And I am expected to pay for the whole thing
    - Yet can not influence any of the process

  22. Its not circumventing, it is working with your doc by rvaniwaa · · Score: 4, Insightful

    I have a rare form of cancer for which I am about 30 years younger than the average person with this cancer. I don't expect my doctor to know much about carcinoid because there are so few of us (he has only treated about half a dozen people with carcinoid).
    Therefore, I feel it is my job to research as much as possible, find experts in carcinoid with which to consult and the latest paper to forward on to my current doc. Medicine should be a cooperative venture between doctor and patient, never just one or the other.
    --Ron

    --
    main(i){(10-putchar(((25208>>3*(i+=3))&7)+(i ?i-4?100:65:10)))?main(i-4):i;}
  23. Similar: I did it, it was fun and weird (Pharmaco) by timothy · · Score: 2, Informative

    I did a few Pharmaco studies -- one complete, one where IIRC I was a standby, and turned out not to be needed.

    It wasn't too bad: I've described it before as a mix of summer camp, hospital, insane asylum, and low-security prison. (These last three, I guess could be usefully combined.)

    The biggest problem is that I failed to think as I should have about hydration: you need to drink enough water if you're going to have a fair amount of liquid extracted through holes in your arms; at one point, after various unsuccessful stabs at my arms, the doctor (who was a bit arrogant and standoffish, but certainly not terrible) gave me a shunt, so I didn't have to get stuck any more, and advised me to drink water so I'd have more to give, so to speak.

    I got more schoolwork done there than I probably did on any other weekends, which was good, because that's not something I was winning any awards for. The food was bland but edible; the only thing I didn't eat was the mayo-containing coleslaw. Entertainment was scarce -- pool, television, a bank of phones -- but there was a computer room, and I brought books.

    It's regimented and strange -- but for a couple of weekends, I got iirc $600, and an understanding of the place / system, and I don't regret it. Maybe I'll do it again sometime, out of interest / curiosity at how it's changed in the last decade than anything else.

    timothy

    p.s. There are lots of rumors about the studies there, including the fabled "heart stopper" where they give you $40,000 to stop and then re-start your heart. Likewise, the "lose a toe" one, where they amputate a toe to test some anti-bleeding drug. I dunno about the veracity of either, but I know when I laughingly told my brother about the heart-stopping one, he paused and asked "Really? 40 thousand?" very thoughtfully.

    --
    jrnl: http://tinyurl.com/c2l8yr / foes: http://tinyurl.com/ckjno5
  24. Health misinformation can be very dangerous. by nilesh_tms · · Score: 3, Interesting

    Misinformation on the internet can be very dangerous. Things like the Typing Injury FAQ are probably more harmful than good. RSI tends to be more of a psychosomatic issue. Sites like the Typing Injury FAQ reinforce the false idea that it is physical problem.

    I say this both from experiencing it for myself and years of research into "RSI" (while I had the symptoms of). The only thing that ever made sense and was able to cure me was John E. Sarno's book "Mindbody Prescription." Do a Google search for "sarno tms" for more info (though the link above on the Harvard site is the best starting point to understand what he is talking about).

    Take random health information on the internet with a grain of salt, especially since it can cause you to exhibit psychosomatic problems if you are prone to it (which more people are than you would think).

    I know this is a controversial idea, but please at least read all of the document I linked to and give it a chance.

    1. Re:Health misinformation can be very dangerous. by Idarubicin · · Score: 2, Informative
      Note that the link helpfully tells how to handle a typing-related repetitive stress/strain injury. Apparently, it's all in your head, and as soon as you clear out the negative emotions, you're all set. You just need to buy the book to learn how:
      Don't go home and just try to start typing. If it starts to hurt, you might get scared and start doubting yourself. Read Dr. Sarno's books and then decide if this is right for you. You will find more instructions there on how to proceed and get better.

      Many people can eliminate their symptoms simply by reading one of Dr. Sarno's books. Some people need a little more help. If reading his book doesn't "cure" you, there are a few other options:

      I didn't add the emphasis to the document; it was already present. The parent poster is at best well-meaning but poorly informed; at worst an astroturfing shill. Note that his user name ("nilesh tms") even includes the acronym for Sarno's proposed disease: "Tension Myositis Syndrome". His only posts on Slashdot have been to promote Sarno's work.
      --
      ~Idarubicin
    2. Re:Health misinformation can be very dangerous. by Bob+Cat+-+NYMPHS · · Score: 2, Insightful

      One of the signs of quackery is the claim that you can cure dozens of diseases with your 'discovery'. Sarno fits the bill.

      "In the course of his medical experience, Dr. Sarno realized that TMS is not just limited to musculoskeletal manifestations. Following is a list of conditions which Dr. Sarno believes commonly serve the same purpose. They are conditions which, emotionally induced, can work as a distraction and can be cured through education and awareness.

      Low back pain, diagnosed with one or more of the following: Sciatica, Osteoarthritis, Spinal stenosis, Herniated/bulging/degenerated lumbar disc, Scoliosis, Spondylolysthesis, Piriformis syndrome, Weak/inflexible torso or hip muscles, Spina bifida occulta, Spondylolysis, Transitional vertebra.
      Neck/shoulder pain, diagnosed with one or more of the following: Osteoarthritis, Pinched nerve, Herniated/bulging/degenerated cervical disc, Whiplash, Thoracic outlet syndrome, Weak/inflexible neck, shoulder girdle, or rotator cuff muscles, Rotator cuff tears, Bursitis, Tendonitis.
      Knee pain, diagnosed with one or more of the following: Tendonitis, Torn meniscus, Chondromalacia, Unstable patella, Muscular imbalances around the knee joint, Osteoarthritis
      Elbow pain, diagnosed with one or more of the following: Tennis elbow, Tendonitis, Muscular imbalances around the elbow joint, Osteoarthritis
      Foot/lower leg pain, diagnosed with one or more of the following: Tendonitis, Plantar fasciitis, Plantar metatarsalgia, Neuroma, Flat feet, Calcium deposit/heel spur, Shin splints, Muscular imbalances around the ankle or foot joints, Osteoarthritis
      Wrist/hand pain, diagnosed with one or more of the following: Carpal tunnel syndrome/repetitive stress injury, Tendonitis, Muscular imbalances around the wrist or hand joints, Osteoarthritis
      Nerve dysfunction, diagnosed with one or more of the following: Sciatica, Carpal tunnel syndrome/repetitive stress injury, Trigeminal neuralgia/tic douloureux, Bell's palsy
      Temporal mandibular joint syndrome (TMJ)
      Fibromyalgia
      Myofascial pain syndrome
      Tension myalgia
      Chronic pain
      Gastrointestinal disorders: Heartburn/acid reflux, Hiatus hernia, Gastritis, Ulcer, Nervous stomach, Spastic colon, Irritable bowel syndrome, Colitis
      Circulatory disorders: Tension headache, Migraine, Raynaud's phenomenon (excessively cold hands/feet)
      Genitourinary disorders: Frequent urination, Urinary tract infections, Prostatitis
      Cardiac disorders: Rapid pounding heartbeat (paroxysmal auricular tachycardia), Extra (ectopic) heartbeats
      Immune system disorders: Allergies, Asthma attacks, Frequent infections, Skin disorders, Epstein-Barr syndrome
      Psychological disorders: Depression, Anxiety, Panic attacks, Obsessive-compulsive disorder
      Miscellaneous disorders: Dizziness/vertigo, Tinnitus (ringing in the ears), Chronic fatigue syndrome, Laryngitis/spasmodic dysphonia"

  25. But we do this already by Ars-Fartsica · · Score: 2, Interesting

    Every day laypeople put drugs in their bodies, some of which have been later determined to be harmful, often not by research performed by doctors, but simply by observations over time. Note also I specifically stated "mentally fit", by which it is implied the person has some understanding of what they are doing, and the risks involved. This really isn't that radical, there have been many cases whereby rational individuals simply cannot afford to wait for the FDA.

  26. SERIOUSLY rolling the dice... by rewt66 · · Score: 3, Insightful
    My mother has arthritis in her hands. She had been on stronger and stronger medicine, and finally was placed on an FDA-approved drug trial. The new medicine was really helping her...

    And then one day she got a phone call: "Stop taking that medicine. Don't take the next pill. Go see your doctor immediately." One of the other patients had died from a side effect of the medication.

    But for my mother, it was a real miracle drug. It has put her arthritis in remission for 10-15 years - and that is unheard of in the world of arthritis treatment.

    Fen-phen comes to mind as another example. Playing games with stuff that hasn't been well studied may have great benefits, or serious consequences, or both. If the FDA hasn't done due diligence (or if you don't trust the FDA), then you'd better do your homework like your life depends on it. Don't just look for the reports of how wonderful the results can be - look for how bad the downside can be.

  27. Re:New Test subjects? by Perl-Pusher · · Score: 2, Informative
    Well here is just a small list of incidents that can easily be verified:

    The CDC Tuskegee experiment
    1955 - Army Chemical Corps continues LSD research, studying its potential use as a chemical incapacitating agent. More than 1,000 Americans participate in the tests, which continue until 1958. 1955 - The CIA, in an experiment to test its ability to infect human populations with biological agents, releases a bacteria withdrawn from the Army's biological warfare arsenal over Tampa Bay, Fl. 1953 - Joint Army-Navy-CIA experiments are conducted in which tens of thousands of people in New York and San Francisco are exposed to the airborne germs Serratia marcescens and Bacillus glogigii. 1953 - CIA initiates Project MKULTRA. This is an eleven year research program designed to produce and test drugs and biological agents that would be used for mind control and behavior modification. Six of the subprojects involved testing the agents on unwitting human beings. 1953 - U.S. military releases clouds of zinc cadmium sulfide gas over Winnipeg, St. Louis, Minneapolis, Fort Wayne, the Monocacy River Valley in Maryland, and Leesburg, Virginia. Their intent is to determine how efficiently they could disperse chemical agents. 1953 UK. NAZI scientists were involved in the nerve gas research that led to the 'suspicious' deaths of at least 25 ex-servicemen at the top secret Porton Down base. [Media] British nerve gas death tests 'had Nazi scientists' 1951 - Department of Defense begins open air tests using disease-producing bacteria and viruses. Tests last through 1969 and there is concern that people in the surrounding areas have been exposed. 1950 - Department of Defense begins plans to detonate nuclear weapons in desert areas and monitor downwind residents for medical problems and mortality rates. 1950 - I n an experiment to determine how susceptible an American city would be to biological attack, the U.S. Navy sprays a cloud of bacteria from ships over San Franciso. Monitoring devices are situated throughout the city in order to test the extent of infection. Many residents become ill with pneumonia-like symptoms. 1947 - Colonel E.E. Kirkpatrick of the U.S. Atomic Energy Comission issues a secret document (Document 07075001, January 8, 1947) stating that the agency will begin administering intravenous doses of radioactive substances to human subjects. 1947 - The CIA begins its study of LSD as a potential weapon for use by American intelligence. Human subjects (both civilian and military) are used with and without their knowledge. 1946 - Patients in VA hospitals are used as guinea pigs for medical experiments. In order to allay suspicions, the order is given to change the word "experiments" to "investigations" or "observations" whenever reporting a medical study performed in one of the nation's veteran's hospitals. 1945 - Project Paperclip is initiated. The U.S. State Department, Army intelligence, and the CIA recruit Nazi scientists and offer them immunity and secret identities in exchange for work on top secret government projects in the United States. 1944 - U.S. Navy uses human subjects to test gas masks and clothing. Individuals were locked in a gas chamber and exposed to mustard gas and lewisite. 1943 - In response to Japan's full-scale germ warfare program, the U.S. begins research on biological weapons at Fort Detrick, MD. 1942 - Chemical Warfare Services begins mustard gas experiments on approximately 4,000 servicemen. The experiments continue until 1945 and made use of Seventh Day Adventists who chose to become human guinea pigs rather than serve on active duty. 1945 - "Program F" is implemented by the U.S. Atomic Energy Commission (AEC). This is the most extensive U.S. study of the health effects of fluoride, which was the key chemical component in atomic bomb production. One of the most toxic chemicals known to man, fluoride, it is found, causes marked adverse effects to the central nervous system but much of the information is squelched in the name of na

  28. Wow...Time to inject some humor here. by KipCas · · Score: 2, Funny

    I have been subjecting myself to drug experementaion on and off for years with a certain weed indigenous to just about any place with dirt. And can report only one bad side effect. I don't remember her name, but she keyed my car and took a bunch of my CD's. Other than that I'd say I do quite well and my IQ has always tested well above average. I mean, come on, I used the word "Indigenous". That means I'm smart. And if I do something that makes me seem stupid I can always just say, "Oh sorry, I'm pretty high right now." It's a win/win situ...it's um...what were we talking about again?

    --
    Turk: Let's play Steak. J.D.: What? Turk: Steak. The 1st person to finish their steak is the winner of Steak. -Scrubs
  29. Experimental drugs vs. tried and true alternatives by vorpal22 · · Score: 4, Interesting
    Drug law and the pharmaceutical industry both baffle me completely, in a theoretical sense and from personal experience.

    There seems to be a whole branch of the pharmaceutical industry that is interested in deriving new medications to substitute for older tried-and-true medications, because the older meds often demonstrate "positive side effects" that we somehow view as undesirable.

    What we're ignoring is that while the newer medications may eliminate the positive side effects (which may be addictive, or encourage abuse of medications, etc), these are not just vanishing; they're often being replaced by negative and potentially dangerous side effects.

    From my own dealings with the medical industry, I present several examples:
    • In 1996, still a teenager, I was cursed with some terrible, painful, and scarring cystic acne. I went to my doctor at the time and requested tetracycline. He instead gave me Accutane as he was hesitant to prescribe antibiotics for this condition. Several months later, for no situational reason, I became suicidal and tried to kill myself. Suicidal tendencies are now a well-known side effect of Accutane.
    • In 1999, I developed a debilitating case of Generalized Anxiety Disorder. My doctor did not want to prescribe me benzodiazepines (very effective anxiolytics), instead preferring to give me paroxetine (Paxil). Result? It induced, within hours, panic attacks in me. Prior to that point, I had never had a panic attack before. It was determined that I was one of approximately 7% of caucasians deficient in the CYP450 family of liver enzymes, explaining why the medication demonstrated effects within hours instead of within days. This resulted in me also developing Panic Anxiety Disorder. My doctor then wanted to give me imipramine, which had a whole host of negative side effects, including instant death in a small percentage of users. I finally went to see another doctor, who was happy to prescribe me the benzodiazepine alprazolam (Xanax), which worked brilliantly and allowed me to live my life and engage in a cognitive behavioural therapy treatment program to learn long-term anxiety management skills. Note that in dealing with long term users of Paxil, I've noticed that many report that Paxil withdrawal is far worse than benzodiazepine withdrawal despite the fact that Paxil is supposed to be "non-addictive".
    • I pulled a muscle in my lower back in late 2000. The doctor I went to see did not want to give me muscle relaxants for it as he thought they were too addictive, so instead, he provided me with celecoxib (Celebrex). I was in so much pain and so unable to do anything from the stiffness that I was unable to protest, and while it worked, during the treatment I discovered that Celebrex was so new a medication that it had only undergone a couple of clinical trials and had rushed to be released. I felt thoroughly like a guinea pig, particularly in light of the fact that several years later, Celebrex has largely been yanked from the market as it can cause possible heart problems.


    The list can go on: Ultram invented for pain in lieu of the opioids (despite the fact that it's still very addictive), Ambien invented for inducing sleep instead of barbiturates and benzodiazepines (because it was, and still is assumed to be safer - ignoring the fact that it can and often does cause dramatic hallucinations at standard prescribed doses).

    Personally, when I have severe pain, I want codeine or morphine. When I need to be sedated, give me some Valium. Don't try to haul this new, safer, poorly researched crap on me. Opiates, for example, have been in use for hundreds or thousands of years, and are well understood. I'd be much more likely to put my faith and comfort in them than some experimental drug that's but a couple years old.
  30. OT: A little editorial advice by hey! · · Score: 5, Informative
    Y'know, this is an interesting article, but it is classic case of "burying your lead". It starts of almost as if it is about the new NIH regs. I had to read it several times to make positively sure I understood what was going on.

    Here is the original article:


    ghostlibrary writes "Even while NIH is getting new ethics regs, patientINFORM is being evangelized as a way for ordinary citizens to look up experimental treatment online, in essence circumventing their doctor, and the FDA long ago the tacitly approved this. /. debated Wikis in hospital. RSI fans track risky or untested procedures from the Typing Injury FAQ and Health-Hack covers IT-related self-help medicine. Laser-eye stuff is now mainstream and doesn't need a check beyond google. Any other sites out there for those willing to dictate their own medical course? Does this mean Internet users will become test subjects moreso than the usual college students and elderly?"


    Let me suggest this as a better rewrite:

    ghostlibrary writes "People who are interested in obtaining information about experimental treatments for health conditions can turn to a new web site called patientINFORM, which is being evangelized by a collective of publishers and medical groups. This site is controversial because it in effect allows patients to circumvent their doctors in the search for unconventional and unapproved therapies. While the FDA has tacitly approved this kind of information service in the past, the NIH is about to issue new regs covering the conflicts of interest this kind of service raises. This site joins other sites that disseminate information about risky or untested procedures, such as the Typing Injury FAQ, which covers RSI (repetitive strain injuries) or Health-Hack, which covers IT-related self-help medicine. Laser-eye stuff is now mainstream and doesn't need a check beyond google, and past Slashdot articles have even discussed the advisability of using wikis in hospitals.

    Are there other sites out there for those willing to dictate their own medical course? Does this mean Internet users are joining the usual college students and elderly as experimental subjects for untested therapies?"


    I think this is a bit clearer. A general word of advice -- try to put what an article is about in the first clause of the first sentence if possible
    --
    Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
  31. Be involved! by Pedrito · · Score: 4, Interesting

    Whoever described doctors as "techs" was right on. Anyone who isn't actively involved in their own treatment is being absoutely careless. I decided this years ago, but it came crashing home when I got misdiagnosed by 3 doctors who said I had asthma based on very sketchy evidence. I was promptly put on a steroid inhaler for daily treatment and an albuterol inhaler for emergencies.

    Now, the reason I went to 3 other doctors (the 4th being the one who correctly diagnosed my problem), is that the albuterol (a stimulant that opens the airways) was making my attacks WORSE, not better. But the second and third doctor said it was all in my head and to stick with it.

    It turns out I was actually having panic attacks. So the last thing I really needed was to be sending a stimulant directly into my lungs which is just shy of injecting one right into your veins. I actually stopped taking the albuterol shortly after the second idiot doctor and just kept going back saying the same thing until I finally got a doctor who was willing to actually check if I really had asthma.

    Now this is just a single example, but it's also not the first misdiagnosis I've had. I've been prescribed antibiotics for flu. I've been told I had food poisoning when I didn't.

    There are some good doctors out there. There are a number of really, really, bad doctors out there. And most doctors, good or bad, are rarely willing to take the time to really investigate their patients' problems these days. You simply can't count on doctors to do the homework on your condition. Someone should be doing the homework. The doctor can run tests, but what if they're not running the right tests? You need to do at least some homework and be willing to make suggestions to your doctor. And if that bugs your doctor, find a new one.

    I know we can't all get medical degrees and it should be the doctors' job to figure all this crap out, but the fact is with HMOs and the like, doctors aren't doing their jobs. They're working on a factory line and getting through as many patients as they can as quickly as they can.

  32. Medical Tourism time... less cost, more ownership by geekotourist · · Score: 2, Insightful
    (oh, and add to your list - Depending on the results, a flag gets added to your Permanent Medical Record aka the Medical Information Bureau , making it permanently more difficult to get individual health insurance. Remember to get your free yearly credit-style report to see how near-death they think you are. Insurance decisions are not supposed to be based only on your MIB. right.)

    While it might not apply to your single-test request, Medical Tourism might help. In your case, for less than the total cost you mention you might be able to fly or drive to a nearby country and get the same test, but in a way that you own the results. More commonly, medical tourism is used to either get an extensive set of medical tests done for a fraction of the U.S. cost (if you could get your HMO to authorize the set in the first place), or to get specific surgeries or dental procedures done for far less than the U.S. cost.

    The well-known m.t. hospitals have the same equipment and safety standards as U.S. hospitals, but much cheaper prices. Plus you get your own data and the hospital room is like a resort hotel, sometimes with beach nearby.

    As examples, a friend needed $20,000 worth of dental work done (as estimated by U.S. dentists). His total cost was less than $5,000 in Costa Rica (including plane tix: Costa Rica is known for dental m.t.), plus he got some ecotourism time in the rain forests. Several of the m.t. hospitals in Thailand and elsewhere have had their business skyrocket after 2001: families who used to visit the U.S. for their yearly checkups (Mayo clinic or similar) aren't being allowed into the U.S. (i.e. a drop of 40% from Middle Eastern countries. Stop the most U.S. friendly people in these countries from seeing their long-term doctors and keep their money away from U.S. businesses: great PR and great economic planning, with no appreciable safety benefits. ).

    M.T. also allows you to truthfully say you're going off for a vacation when you're going to get elective surgery like liposuction or plastic surgery done. On your return you'll get "Hey, you look better...nice tan."

  33. Re:Insurance isn't. by wodgy7 · · Score: 2, Insightful
    Be careful with this. In the US, believe it or not, if you don't have insurance and end up in the emergency room, you don't pay the same amount as someone who has insurance. Usually you end up paying the hospital's top rate for the procedure, which is far more than someone with even cheap, high-deductible insurance would pay.

    It doesn't make a lot of rational sense -- why should people who often can't afford insurance pay the highest prices? -- but it is an artifact of the way the system is designed. Hospitals set a high fee by default and then negotiate steep discounts with insurance companies. Individuals don't get these same discounts. Recently, there have been plenty of articles in the Wall Street Journal about this and other aspects of health care economics.

  34. Re:I got no insurance by Ars-Fartsica · · Score: 2, Insightful
    ill-defined caveat regarding the nebulous property of 'percieved value to others'.

    It is not nebulous or ill-defined at all, it is quite plainly spelled out in the narcotics laws of your local jurisdiction, which are by definition the local standards for materials that impose a higher perceived cost than benefit. If none of this makes sense to you, try Tierra del Fuego, I hear you can set up your anarchy there for little cost.

  35. Lyme disease, or why doctors suck by b0s0z0ku · · Score: 2, Insightful

    Well, about a year ago, I was bitten in the head by a tick. Developed joint pain, characteristic rashes in several places on my body, headaches, frequent bouts of feeling like shite, wierd urinary issues, etc. In short, all the symptoms of Lyme Disease.

    Went to my usual doc; he tested me for it using the (quite flawed) ELISA test. Came back negative and all other bloodwork was fine. Two months later, I has a bad case of sinusitis, and was given an antibiotic which just happened to be effective against Lyme.

    After experiencing a worsening of symptoms (known as a Herxheimer reaction) on the third day of treatment, I started feeling much better. Joint and back pain was reduced almost to zero, headaches were gone for the first time in 10 months or so.

    Of course, the doctor said: "you can't possibly have Lyme, you tested negative for it." I told him that I read that the test is not 100% accurate and the NJ state health depertment had even advised doctors not to use it as the sole diagnostic criterion. "Well, ... stop reading so much and worrying about your health. The fact that antibiotics helped you is probably just the placebo effect." (stupid fucktard, as if it isn't known that joint pain is often caused by bacterial infections.)

    So far, after 10 days of that antibiotic (Omnicef) and a week more of self-administered amoxicillin, my symptoms are 90% gone, but since 2 and a half weeks of antibiotics isn't enough to treat Lyme, they'll undoubtedly come back.

    Fortunately, I was given the name of a good specialist, whom I'm seeing in two weeks, and there is still a faint mark from one of the rashes, so there is evidence that I was infected. I suppose that if I were desperate, I could always go to Mexico and get antibiotics or order them through a pharmacy site like Master's Marketing, which is reputable but isn't too particular about prescriptions for non-narcotic drugs.

    -b.

  36. Re:Little Boys & Hammers by RzUpAnmsCwrds · · Score: 2, Insightful

    The reality is, there *is* no alternative medicine. There is tested, proven medicine, and there is untested, unproven medicine.

    It's certainly possible that Osteopathy has benefits. But unless you can provide the studies that *back that up*, I'm going to stick with what is proven.

    It's common for "alternative" medicine believers to tell grandiose stories about how the "establishment" is trying to cover up their mistakes and promote "bad" treatments.

    But, think about this: if "conventional" medicine is really so bad, why does it work so well? When I take 10mg of loradatine (Claritin), my allergies clear up. I can feel the effect - and, more importantly, double-blind tests can measure the effect.

    Medicine, like all sciences, is an evolving process. We've been wrong about a lot of things in the past, and we're wrong about a lot of things today. But I'd rather take an imperfect system than one that is completely unproven.

    "A core tenet of Osteopathy is that Structure and Function are interrelated - hence the importance of applying appropriate adjustments to the body's structure (spine, bones, muscles and tendons) to a body that is not functioning properly."

    There's another crap argument. You make the statement that it's a "core tenent" without actually backing it up. Where are the studies that *show* that structural adjustments can fix chemical problems? You have neither described the mechanism nor provided evidence that your method works.

    Believe what you want. I'm going to believe what's tested and verifiable.

  37. Re:Little Boys & Hammers by mbaciarello · · Score: 2, Insightful

    An allopath (99% of M.D.s) believes that a body's symptoms are the problem, and gives his patients substances which counteract the symptom.

    Man, does this reek of superstition and scam...

    You didn't stop for a minute to think what antibiotics, antivirals, surgical excision of a tumor do, right? I'll tell you: they remove the cause of your illness. Symptoms are cured to make you feel better, as well as to provide relief when the initial cause of the disease cannot be treated.

    If you got off the magic carpet and looked up "angioplasty" on Google, you'd find out that it's used to actually reopen clogged up arteries, not just make a patient's chest pain go away.

    The same goes for many, many therapies and procedures in so-called "allopathic" medicine. You believe in pure superstition, based on utter ignorance of what medicine is today.