Scientists Create New Human Embryonic Stem Cell
Homework Help writes "U.S. scientists were successful in creating a new human embryonic stem cell. From source, "U.S. researchers said on Monday they have created a new human embryonic stem cell by fusing an embryonic stem cell to an ordinary skin cell.
They hope their method could someday provide a way to create tailor-made medical treatments without having to start from scratch using cloning technology.
That would mean generating the valuable cells without using a human egg, and without creating a human embryo, which some people, including President George W. Bush, find objectionable.
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That would mean generating the valuable cells without using a human egg, and without creating a human embryo, which some people, including President George W. Bush, find objectionable.
should read:
That would mean generating the valuable cells without using a human egg, and without destroying a human embryo, which some people, including President George W. Bush, find objectionable.
To echo something I said the other day: personally, speaking as someone whose training has been almost exclusively in medical science, I fully support embryonic stem cell research. We have embryos that are and will continue to be destroyed today, that could absolutely be harvested for research. However, to ignore any ethical debate on such issues is just as ignorant as some would paint the opposition. Scientifically, an embryo is, strictly speaking "human life"; so, when and why is it ok to end such life, regardless of the state it may be in? Why should we not examine the important ethical questions? There is absolutely no doubt that significant scientific benefit could come from cloning or farming of humans in more developed forms. So should we push forward with things such as that, full force? Or should we take pause ask important questions that define our very humanity?
Remember - and admittedly, this was due in part to the timing of discoveries, but is true nonetheless - President Bush is the first president to allow federal funding of any kind to human embryonic stem cell research. Further, there were no "bans" on embryonic stem cell research: there was a restriction on federal funding of research that didn't use approved, preexisting lines. Without regard to the purported scientific use{ful,less}ness of the existing lines, the fact remained that funding was indeed provided, human embryonic stem cell research (including the destruction of embryos) was not banned, and a conservative approach was taken. Further, large research entities - such as the state of California and the University of Wisconsin System - have had little difficulty in establishing research centers to skirt federal funding restrictions and still commit federal-scale research funds to embryonic stem cell research.
The ethical considerations are important: should we also clone humans? After all, aren't you "anti-science" if you oppose unrestricted human cloning?
Just because something is nothing more than an amalgam of cells - or a single cell - doesn't mean it doesn't represent, even if only philosophically, human life. Why is it valid in the macro scale, but not micro? Note I'm not saying that even embryonic stem cell research that involves the destruction of embryos - indeed, embryos that would have been discarded anyway - shouldn't be done; I am saying that there should be ethical debate and discussion: as I'm sure many would agree, just because you can do something doesn't necessarily mean you should.
In any event, I applaud researchers for finding a potential method that may allow embryonic stem cells to be used without the associated destruction of human embryos, thereby removing a significant and valid ethical consideration as a barrier to the further exploration and use of these cells as potentially valuable tools.
Note: I didn't vote for Bush, and don't personally support Bush's current human embryonic stem cell policy.
Please keep that in mind before you start bitching about us Christians being anti-science.
I just read an article about this, don't know how close it is to this one, but it was stated that the converted stem cells retain the DNA of the doner. The significance of this is that any organ or body part derived from that stem cell could be safely transplanted into that person without fear of rejection. Nifty.
Even though this is good news for science and the future of medicine, this is Slashdot; I feel like I should start an inflammatory politically charged internet argument that will result in hundreds of follow up posts and lots of angry name-calling.
So, allow me start us off:
I hate Bush. Discuss.
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Perhaps you'd like to try this totally untested stem-cell treatment for that nasty cough of yours?
~~~~~ BigLig2? You mean there's another one of me?
when we can have baboons, fish and any other creature with eight asses. What a glorious day that will be!
There exists no way of exchanging information without making judgments. --Bene Gesserit Axiom
Insightful, too, though. The president has a moral obligation to do what's best for the country as a whole instead of acting out of his own personal religious beliefs.
quidquid latine dictum sit altum videtur.
The problem with stem cells is that conditions must be met for those cells to become differentiated cells.
Take a skin-type stem cell. It will have to have some kind of trigger to tell it to turn into a skin cell and not say..a nerve cell that attaches to the skin, or an oil-producing-cell, etc. These triggers are tiny, have to be given at the right time, and probably won't be easy to produce.
Its like having a batch of nano-goop that will eat the resources available and turn itself into an object, but you have to find out how to tell it that, by hand.
Job? I don't have time to get a job! Who will sit around and bitch about being broke and unemployed then?
There's a lot more to the genotype of a somatic cell than DNA: cells accumulate a whole bunch of 'markers' such as methylated bases and proteins stuck to the DNA, and repeat units that fall off the ends of the chromosome with every cell division.
Nature has good mechanism for making sure germ line (reproductive cells) stay in a good state, but manipulated cells never seem to be 100% right. Clones often end up with poor health and life expectancy because of this, and I'm afraid stem cell therapy will end in poor results, maybe even cancer.
It's bizzare that stem cells have become such an issue for the left and the right. I see Democrats screaming at the top of their lungs so we can have more research into medical treatments that we can't afford, while Republicans are blowing the ethical issues entirely out of proportion.
I am against this, because I was only for stem cell research as a byproduct of killing babies.
I used to have a cool sig, back when I cared
Actually, the National Institute of Health is the federal agency that assigns the funding in question. The NIH is part of the Department of Health and Human services, which is part of the executive branch, which the president is the head of. There's your constitutional basis.
Unfortunately, a lot of this research gets picked up by the anti- side and used as evidence for the (false) view that scientists are just "lazy" or politically motivated, and there are lots of alternatives to embryonic stem cells just lying around if they were willing to use them. Unfortunately, most of these alternatives are not ready for prime time, and won't be for years, maybe decades-- if ever (in fact, you'll see many of them melt away, never to be heard from again once science proves them dangerous or unsatisfactory). Most scientists would like to see this research happening now, because even if it takes decades to result in a cure, a five year head start could mean useable treatments a few years earlier than if we wait. And in some cases, that could save thousands of lives.
You'll also notice that most of the embryonic stem cell research plans currently being proposed make use of excess embryos from IVF clinics, and only after effort has been expended to reduce over-production and boost embryo adoption (which currently is not very successful, but might take off with enough encouragement). Surprisingly few mainstream politicians and scientists are strongly advocating therapeutic cloning, although that technology has even more promise.
Executive orders do not have (and never have had) the force of law. Congress can override them simply by passing a law contradicting the order, and the Supreme Court can strike orders down (and has in the past). The only type of orders that do have force of law are those made in pursuance of certain Acts of Congress which give the President discretionary powers.
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For starters, I don't think anyone has proposed any use of stem cells to fight cancer. So while I respect the emotion of your position, you seem to have no grasp of the actual specifics of the issues whatsoever. That makes you both passionate and uninformed. A dangerous combination. Putting that aside... My grandfather - who was extremely healthy, relatively young, and whom I was very close to - passed away last summer from stomach cancer. My wife's mother (I actually LIKE my mother-in-law) has been battling breast cancer for 15 years and is currently going through yet another round of chemo. Diseases like this suck, and I hate them. But the truth is that I believe that even if I myself had cancer, I would refuse a treatment that involved using stem cells from an aborted embryo. For the same reason that I would refuse to have my life spared by the killing of an infant, a toddler, or any other human. Sure, you can taunt me and claim that I don't know because I haven't been there and that such high-minded principles fall by the wayside in the struggle for life istelf. But those are my principles, and they are what I beleive in. No matter how bad the experiences in your life have been I think you need to be open to the possibility that other view points can also have compelling motivations and stir up just as much passion as your own. Finally to the argument in general, I'm specifically opposed to stem cells harvested from destroyed embryos. I am also uncomfortable with the use of "discarded" embryos, and I am also uncomfortable with the whole notion of discarding (or even freezing) embryos that are left over from fertility treatments. I say "uncomfortable" and not "opposed" because I think conviction should be a function of both your opinion of the relevant facts and your degree of certainty in the relevant facts. I think it would be good if more people followed that principle.
The Southern Baptist Convention has creationism. On Slashdot, we have porn.
They're trying not to. They'd rather not be forced to pay for it, via taxes.
I think the biggest issue here is exactly how people define life. Right now the focus seems to be around "if there's conception, there's life", though there's all sorts of issues that make things complicated. Stem cells from umbilical cords seem fine to most folks because it's something typically seen as tossed away. Extracting bulk stem cells from people's brains is probably a no-no, though stem cells from fat tissue is fine.
The bottom line is that there's no obvious definition over what constitutes a living person and what isn't. As someone with a master's degree in biology, I've decided there never is going to be one ("life" will be one of those words like "justice" or "freedom" that mean many things to many people).
What people will find, of course, is that there's a way to reprogram adult cells so that it looks and acts just like embryonic stem cells. Of course, that means that you could turn it into something that looks an awful like a human being. If any cell in your body has the potential for turning into a full-grown human, does that mean liposuction is murder? If I create a stem cell from scratch, can I grow them to term and sell them as non-human slaves?
I'm not necessarily advocating either side in the debate, only that it's one of those ethical decisions rather than something science dictates as fact. I suspect it'll be argued over for many decades to come.
Hey, as long as you're speaking for all Christians everywhere -- evidently including me and my extended family, despite none of us ever having signed over any plenipotentiary powers to you -- why don't you go ahead and just tell us what God thinks? You're already speaking for other human beings whose minds you plainly DO NOT KNOW; why not go for the Go(l)d?
See, there's a subtle distinction to be made, there -- or really a not so subtle one, yeah? -- about your own views versus those of all Christianity. It's a distinction that you've missed a handful of times in the course of your three sentence post.
Which makes me a little wary of handing over any sort of moral authority to you and your like-minded authoritarian wannabes when it comes to medical science. You dig?
"Fundamentalism" isn't about divine morality. It's about human authority.
From what I hear, most conservatives base their opposition to embryonic stem cell research based on their belief that life begins at conception, producing a unique organism that God grants a unique soul.
I have several questions for all of you:
1) Conception takes place before implantation in the uterus. If you don't already know, many contraceptives work by blocking implantation. Since a conceived zygote is being blocked from developing further (and will die), is this murder?
2) At the stage the cells are taken from (blastocyst), a biologist could divide the inner cell mass (any one of which is used for embryonic SCR) and what would happen is that twins or triplets would develop. If you believe each child is given a unique soul at conception, does that soul also divide into two or three? Or does God give "last-minute" souls out?
My point, if it's not clear, is that embryonic stem cells are taken at a stage when it is not individually unique. A lot of people also seem to be happy with either in vitro fertilization or birtch control pills while opposing embryonic stem cell research.
Light a fire for a man and he'll be warm for a day. Light a man on fire and he'll be warm for the rest of his life.
The president has a moral obligation to do what's best for the country as a whole instead of acting out of his own personal religious beliefs.
Strictly speaking, he does not have that obligation, nor that power. He can recommend to the Congress "such Measures as he shall judge necessary and expedient." He must do what is necessary to uphold the law of the land.
But the power to act lies within Congress, and any recommendation by the President is based upon his personal opinion, which may or may not reflect what is best for the country.
This is why there is a separation of powers, so that the Congress can hold a President, who either oversteps his authority, or is an idiot, in check.
"Trolls they were, but filled with the evil will of their master: a fell race..." -- J.R.R. Tolkien on Olog-hai
Stem-cell cures are probably two decades away, if proven viable.
No side of the stem-cell debate is AT all honest.
On the left...
The pro-embryonic research crew is 1, telling sick people that George Bush is killing them, when in fact they have a death sentence and stem cell research may cure FUTURE patents, but not likely the current ones.
This is more about politics than anything else. A prohibition on federal funds isn't a prohibition on research. Bush was the first President to approve ANY funding, and allowed it for pre-existing lines. That may not be enough lines for major research, but it should have given a start to doing some of the basic research to determine if this is viable. Unfortunately, people would rather play politics. I expect the pro-choice crowd to be EXTREMELY upset at this research, that manages to create research lines WITHOUT destroying life, as many of the vocal members aren't focused on the research, but a believe that every embryo destroyed someone secures their agenda.
On the right...
Federal funding is generally key to any EARLY stage research. Cutting off federal funds DOES slow down basic research.
This is a closet attempt to deal with their moral issues with IVF, not the activity, but the discarding of embryos.
If this discovery is confirmed then it means that Bush's compromise worked out wonderfully, whether you like him or not. He allowed the basic research to continue, and scientists found a solution.
Do you think that if every undergrad biology student could get a vial of embryos as part of a basic lab class (if you listen to the argument on the left that there is NO MORAL question), this research would have been heavily pushed or developed?
The pro-choice crowd was EXTREMELY excited about the ability to destroy more embryos as part of their "proof" that embryos aren't life. The pro-life crowd wanted to start developing embryonic rights. Somehow, Bush managed to placate the religiously motivated conservatives while allowing the research to go on, and low-and-behold, someone may have found a solution that solves the whole problem.
Alex
Doctors hope to someday use embryonic stem cells as a source of perfectly matched transplants to treat diseases such as cancer, Parkinson's and some injuries. [emphasis added]
Currently, doctors are already using adult stem cells to treat diseases such as Parkinson's and some forms of cancer.
Which lends me to believe that the debate about embrionic stem cell research has very little to do with actually creating cures for diseases. It seems to me that the debate is more about the role of science in society than the actual results it produces. It would seem to some that science is man's highest endeavor, capable of doing no wrong. To them, anything, no matter how horrible, is justifiable in the name of science.
But what is really interesting is that the opposition to embrionic stem cell research is not an opposition to science or discovery, but rather an affirmation of the dignity of the human being. They see science as the servant of mankind, not mankind as the servant of science. The fundamental objection of embrionic stem cell research is not an objection to discovery, but rather that the research is being done with a secondary objective of allowing science to arbitrarily redefine what it means to be human.
And this is the fundamental battle over embrionic stem cell research. It has nothing to do with science, and everything to do with removing the role of the church from ethical decisions in public policy.
Interestingly, I still find it ironic that some people believe there is a conflict between science and religion:
- Religion finds answers the ethical questions facing all of mankind.
- Science explains the natural world.
- Together, with the ethical guidelines provided by religion, and the knowledge provided by science, society can make decisions which preserve both the dignity of the individual and benefit society as a whole.
I still find it strange that some people believe that science alone can answer all of the questions facing mankind, or that religion alone can sufficiently explain the natural universe. It's all knowledge folks; it enlightens those who are willing to accept it. Insisting that science somehow "proves" God doesn't exist, or that an ancient religious text "scientifically describes" the creation of the world benefits no one and only shows one's ignorance.The society for a thought-free internet welcomes you.
If we can benefit from the use of embryonic stem cells without the ethical and moral problems inherent in obtaining them from actual embryos, isn't this a win for both sides of the issue? I submit that anyone who objects at this point isn't interested in medical advancement, but has some other agenda, for which this issue is just a proxy.