Slashdot Mirror


Mice Produced Using Artificial Sperm

vasanth writes to tell us scientists have successfully grown mice from artificial sperm. The sperm was created from embryonic stem cells and implanted into female mice. There were a few problems, including that some of the mice showed abnormal patterns of growth and difficulty breathing. The hope here is to assist couples who are having difficulties with conception.

34 of 435 comments (clear)

  1. Artificial Sperm? by lecithin · · Score: 5, Interesting

    Not artificial sperm, but artificially grown sperm.

    People took'sperm seeds' from stem cells and grew them into mature sperm outside the gonads.

    Regardless, it looks like males have one less reason for existance.

    --
    It could be worse, it could be Monday.
    1. Re:Artificial Sperm? by hotdiggitydawg · · Score: 5, Funny

      You mean my sole reason for existence is now opening jars for the missus?

    2. Re:Artificial Sperm? by Jordan+Catalano · · Score: 5, Funny

      "Regardless, it looks like males have one less reason for existance."

      Don't sweat it -- you still need scientists to perform the procedure, and last I checked they weren't letting girls get into science.

    3. Re:Artificial Sperm? by sirinek · · Score: 4, Funny

      You mean my sole reason for existence is now opening jars for the missus?

      Don't forget killing bugs...

    4. Re:Artificial Sperm? by WilliamSChips · · Score: 4, Funny

      I'm pretty sure men and women are the same species.

      --
      Please, for the good of Humanity, vote Obama.
    5. Re:Artificial Sperm? by LordKronos · · Score: 4, Funny

      You mean my sole reason for existence is now opening jars for the missus?

      Ohhhhhh..I have a bad feeling you aren't going to like this:
      http://www.blackanddeckerappliances.com/category-2 07.html

  2. Oh really? by Rendo · · Score: 3, Funny

    It seems women are getting more and more fed up with us males that they're working diligantly on not needing us anymore. We can choose which sex, now we're working on assisting "couples" (of women) in having babies. Damn... At least I've procreated!

  3. Think of the micelings! by Anonymous Coward · · Score: 3, Funny

    Aren't there already enough unwanted, unluved mice babies already?

  4. Heather Has Two Mommies by Doug+Dante · · Score: 4, Interesting
    Lesbian couples can now eliminate the external sperm doner and Heather can have two mommies who are both her biological parents. All children will be girls, unless a Y chromosome is added from a donor and an X is yanked.

    Given some time, eggs may also be made as well as sperm from stem cells, and homosexual male couples can also have biological children with the help of a woman to carry the fetus.

    --
    The world will not get better through technology. We must seek to be better people.
  5. "Difficulties with conception" by Silent+sound · · Score: 3, Interesting

    You know, with some of the recent medical advances I keep idly wondering how long it's going to be before the statement "same-sex couples can't have biological children" is no longer true. After all, there's no particular reason the stem cells used to create the artificial sperm in this procedure would have to come from a male, is there?

  6. Re:The Mice? by Tackhead · · Score: 3, Funny
    > Has anybody thought of the mice? Aren't we playing GOD with them? Shouldn't they have a right to live and roam free and not be subject to those humans obsessed with fertilizing them? Disgusting and definitely unethical.

    Gee, Brain, I guess I wasn't pondering what you were pondering. I was pondering more along the lines of me and Pippi Longstocking. I mean, what would the children look like? NARF!

  7. Initial gut reaction by teasea · · Score: 3, Interesting

    Ummmm....

    Ew.

  8. Welcome to the real-life "Amazon" by scheming+daemons · · Score: 4, Interesting
    The hope here is to assist couples who are having difficulties with conception.

    With this technology, two women could generate a baby that has 23 chromosomes from each of them. Men would no longer be necessary to create a new human being that is genetically half of two different individuals.

    And since both "halves" would be providing an X chromosome and never a Y, the resulting baby would be female... every time.

    If enough women in a society opt for this form of male-unnecessary reproduction, over a few generations there will be no more males in that society.

    I can see Gloria Steinem and others of similar political persuasion creating a female-only society somewhere with this technology. An estrogen utopia.

    I, for one, welcome our Lesbian overlords.

    --
    "I have as much authority as the pope, I just
    don't have as many people who believe it" - George Carlin

    1. Re:Welcome to the real-life "Amazon" by Anonymous Coward · · Score: 5, Funny

      Except for when the technology breaks and there will be no man to fix it.

  9. Help With Conception?! by susano_otter · · Score: 3, Insightful
    The sperm was created from embryonic stem cells... The hope here is to assist couples who are having difficulties with conception.


    So let me get this straight: you want to help a couple make a baby... by making a baby somewhere else, destroying it, harvesting its biological material, and using that material to make another baby, which you then give to the baby-challenged couple?

    I guess the big advantages to working for the Department of Redundancy Department is, you get double funding for everything, and there's always someone else around to do your work for you. But it does seem kind of wasteful, sometimes.
    --

    Any sufficiently well-organized community is indistinguishable from Government.

  10. Female/Female Reproduction by spyrral · · Score: 3, Insightful

    Would this allow two females to produce an offspring together? Because that would be a species changing event for humanity.

    1. Re:Female/Female Reproduction by brianerst · · Score: 3, Interesting
      It doesn't appear that the technology in question would do that (the FA talks about spermatogonial stem cells, so presumably it requires biologically male embryos).

      An interesting meta-question is what might that (female-only reproduction) do to evolution? If we don't move into directed evolution (via DNA tinkering or selective abortion), how would having only female gametes change the rate of evolution? The reason that I ask is that male gametes are created at a fantastic rate, creating trillions of possible chromosomal mutations over the lifespan of a male. Female gametes, in contrast, are created at a very deliberate pace (either early on in the development of the ovaries, or, according to some more recent research, on-demand once a month from ovarian stem cells) - far fewer opportunities to screw up the copying and create a mutation.

      Look at the one chromosome that is male-only - the Y chromosome, the most stunted, bizarrely mutated one of the bunch. Lots and lots of changes occurred on that branch, and without female evolutionary "brakes", it nearly mutated itself out of existence.

      Would female-only reproduction cause a slowdown in genetic drift and mutation? Combined with the technological ability to modify our environment to minimize evolutionary pressures, this could keep humanity percolating at the homo sapiens sapiens level for a long time. An interesting point to ponder...

    2. Re:Female/Female Reproduction by Grishnakh · · Score: 4, Informative

      Yes, it sounds like this could be a really good thing for humans, by stopping evolution cold and keeping mutations out. The problem with evolution is that it's actually a bad thing for humans, because while we still have mutations and such, we no longer use natural selection to weed out the bad mutations. Instead of just allowing sick people to die, we save them with medicine, and they reproduce, making more people with serious genetic diseases.

  11. Money Talks, God + Common Sense Walk by RobotRunAmok · · Score: 3, Insightful

    Why can't more rich, self-absorbed and childless yuppies want to go to Mars? Then maybe our space program would get that much needed shot in the arm...

    Damn.

  12. Re:If god doesn't want you to to have kids... by CosmeticLobotamy · · Score: 3, Interesting

    the fact that god has said NO to a couple should be taken as an extremely stong hint that it just shouldn't be done.

    He didn't say "no", he said "try harder." You'd know God's "no" if you saw it, it doesn't look like what you're seeing. There's more flaming corpses.

  13. Re:If god doesn't want you to to have kids... by LnxAddct · · Score: 3, Insightful

    Screw your god, I'll do what I want.
    Regards,
    Steve

  14. If god doesn't want you to wear clothes... by MarkByers · · Score: 5, Funny

    Then don't. Clothes turn people into lower mamals. Though we don't have the insight right now, I bet in 50 years, we'll figured out why God didn't want you to wear clothes. All life exists for us to look at, and in some species will havve fur, or occasionally produce a viable hairy offsprring. Given life's penchant for procreation, the fact that god has said NO to people wearing clothes should be taken as an extremely stong hint that it just shouldn't be done.

    Become nudist. There are tons of guys waiting for women who actually want to show off their body.

    Just because we can, doesn't mean its right. Or smart.

    --
    I'll probably be modded down for this...
  15. I don't see the use by helicologic · · Score: 5, Funny
    [...] The sperm was created from embryonic stem cells and implanted into female mice. [...] The hope here is to assist couples who are having difficulties with conception.

    How many couples really want to conceive a mouse, anyway?
  16. Re:If god doesn't want you to to have kids... by bsartist · · Score: 4, Insightful

    If God didn't want you to have kids, this procedure wouldn't work. I always get a kick out of people who claim that God is all-powerful, and in the next breath claim that scientists are doing something that's against His will. They never seem to understand the inherent contradiction in those two statements...

    --
    Lost: Sig, white with black letters. No collar. Reward if found!
  17. Re:The Mice? by ch-chuck · · Score: 3, Funny

    The mice are actually pan-dimensional beings cleverly performing experiments on humans, getting pregnent on artificially produced sperm to find out how humans will react, etc.

    --
    try { do() || do_not(); } catch (JediException err) { yoda(err); }
  18. Re:wtf? by flipsoft · · Score: 5, Informative

    Actually it is a misconception that adoption is cheaper and easier. Average adoption costs are $12k US. Significantly more than the doctors bill for our first child. Also adoption, at least in the state of CA, is very dificult and requires 50+ hours of classes. Much more time invested then a couple hours at a bar and some drinks. ;)

  19. No. by Silent+sound · · Score: 5, Informative
    If you'll read the article, you'll see (emphasis mine):

    "If we understand this we can treat infertility in men."

    In the future, men with fertility problems might be able to have their own stem cells harvested using a simple testicular biopsy, matured in the lab and then transplanted back.
    They are using embryonic stem cells because of the benefits that embryonic stem cells offer over other stem cells when doing research. It is clear that once they can get the procedure working with embryonic stem cells in mice, the next step will be to get it working with non-embryonic stem cells.
  20. Re:What abnormalities? by Ohreally_factor · · Score: 4, Funny

    The main abnormality in human children conceived through this method seems to be an unhealthy obsession with cheese and a tendency to scamper.

    --
    It's not offtopic, dumbass. It's orthogonal.
  21. Re:The Mice? by Itninja · · Score: 5, Insightful

    Everbody knows that easily 'humanized' animals (i.e. cute and furry, big eyes, or perceived intelligence) get complete protection. Whereas ugly animals can just suck it. That's why everybody freaked out when they found out dolphins were being killed in tuna nets. But nobody cared that 1000's more TUNA were being killed in tuna nets. I mean, have you ever seen a tuna? They are ug-leee.

    --
    I judt got a nre Kinesis keybiartf so please excusr ant egregiou typos.
  22. Re:They don't need us by CosmeticLobotamy · · Score: 4, Informative

    I hate to have to tell you this, but girls aren't passing you up because you're not aggressive or violent enough, it's because you're ugly, boring, or both. Sorry. If it makes you feel better, I'm right there with you.

  23. OK, I'll be the party pooper here by argStyopa · · Score: 4, Interesting

    I'm not convinced that 'helping infertile couples have children' is the ultimate rationale - is everyone ENTITLED to have children?

    I mean, is it so far fetched to believe that several million years of trial and error have produced a system of conception that is fairly fault-tolerant but will self-abort if a certain minimum level of viability is not achieved? And that short-circuiting this might not be in anyone's best interest - the parents', the child's, society's?

    So then we come in with near-godlike medical technology, and FORCE certain sets of gametes together which would otherwise fail? Am I the only one that has a moral problem with that?

    Personally, I'm a HUGE fan of the 'conventional' method of fertilization; if it works, great. If it doesn't, maybe there's a very good reason it doesn't.

    --
    -Styopa
  24. Heh by Silent+sound · · Score: 3, Informative

    Not so fast, it goes the other way too. Separate research is taking place in the meantime that involves turning donor cells into egg cells-- which would be the counterpart in fertility procedures to the artificial sperm procedure this article is about, and would also hypothetically make possible the conception of a baby with only males donating the biological material.

    When a news article about such research cropped up last year, I saw people on the internet worrying about a science-fiction type scenario where the development could lead to a world devoid of women.

    People get really paranoid about science...

  25. Teriatary effects by phorm · · Score: 3, Insightful

    Well, there are quite a few people who are incapably or semi-incapable for medical rather than genetic reasons. They're born and develop perfectly able to reproduce, but do to accident. For example: getting hit in the nads too hard, or getting an inter-uterine infection, my mother was rendered incapable due to complications of a car accident (obviously after I was born).

    It's also a survival method. What if some new nasty disease or bacteria, etc, rendered a large portion of the human race largely incapable of reproducing naturally. It's always a good idea to have a backup plan... it's just a matter of not abusing the ability.

  26. Sad by fish_in_the_c · · Score: 3, Insightful

    As can be seen by several post here this is sad news, it is degrading to males.
    It is also degrading to babies.

    Such technology is degrading to human beings.
    It treats procreation as being nothing more then a biological process.
    It makes something that should be held as a honor and a privilege ( being a parent )
    into a commodity bought and sold in the laboratory.

    When you reduce procreation to a commodity you reduce people to being a commodity.
    Honestly this kind of technology is evil for the same reason slavery is evil.
    people are not a commodity.

    --
    âoeTolerance applies only to persons, but never to truth. Intolerance applies only to truth, but never to persons.