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A 3-D View of the Brain

Jamie found a nifty story about Researchers at Thomas Jefferson University Hospital coming up with new 3D Brain Imaging Software. The interesting bit is that it merges data from MRIs as well as various other types of brain scans to create a single visualization for your noodle.

18 of 68 comments (clear)

  1. Check out the 'MultiMedia' by Silver+Sloth · · Score: 4, Informative

    As well as TFA there's a 'Multimedia' link which give much more info - as well as having some pretty pictures.

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  2. We all know what a man's brain really looks like- by tomhudson · · Score: 4, Funny
  3. The ultimate geek by GregPK · · Score: 2, Interesting

    Would order pictures of his brain and keep one on his desk in a frame.

    I'm such a dork, because I kinda want one too. :-D

  4. Not likely by $RANDOMLUSER · · Score: 3, Funny

    If it really was a 3D representation of my brain, all you'd see would be tits and code (and maybe some beer).

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  5. for the lazy by bumby · · Score: 2, Informative
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  6. Re:Matching images. by tOaOMiB · · Score: 3, Informative

    All MRI machines can do it all; they are just different programs you feed the machines to get different images. Unfortunately, the images at the end still have to be lined up. This is typically done by allowing the brains to rotate in 3 dimensions until the registration maximizes some function; for example, the mutual information between the two images. See the package fsl (http://www.fmrib.ox.ac.uk/fsl/) for some great fMRI analysis tools, including FLIRT for aligning brains (of multiple patients, or one patient's fMRI scan to MRI scan).

  7. nothing new by j00r0m4nc3r · · Score: 4, Interesting

    Computer-assisted stereotactic neurosurgery has been around for a long time. The software takes MRI slices and uses a marching-cubes-type algorithm to convert from texels to voxels. I don't see how this software is anything new really, other than maybe using some other kind of input image.

  8. Nothing new here... by perrin · · Score: 5, Informative

    I work within the field of medical imaging, and this is nothing new. People have been doing image fusion with images from different image modalities for over a decade. There are lots of products like this one, some even open source and with more impressive screenshots. Why is this particular product, which is not even named or referenced, featured? If you want to see impressive open source work within the medical world, check out ITK and VTK (http://www.vtk.org/ and http://www.itk.org/). Now that is really cutting edge work done with free software.

    1. Re:Nothing new here... by cbelt3 · · Score: 4, Informative

      .. a decade.

      How about over THREE Decades. As a high school student (in the 70's), I worked on software to merge CAT scans and thermal scans of the brain during an NSF summer program at Mizzou. Fortran IV, big honkin IBM 360 mainframe, etc. The first run with a full data load took the entire University mainframe down (hey, I was only 15 and didn't understand JCL, shoot me). We were trying to auto-diagnose tumors.

      The basic engineering has been refined, but the science is still the same.

    2. Re:Nothing new here... by cbelt3 · · Score: 2, Funny

      Oh, you were looking for a display, and maybe a mouse and overlapping WIndows ? Sorry, hadn't been invented yet. We did build a color map display and rotate it, though. This was the Biomedical Image Analysis Lab. Very cool stuff for 1975. Imaging and display ran on a PDP-11...mmm. back in the day. had to boot that sucker by loading in the punch tape boot code sequence in octal, then load paper tape, THEN we could actually load the programs from Mag tape. you guys and your newfangled hard drives don't know how easy you've got it ! (mumbling about steam powered computers and young whipper-snappers..)

  9. "noodle" by jo42 · · Score: 3, Funny

    My "noodle" is nowhere near my brain...

    1. Re:"noodle" by B4D+BE4T · · Score: 2, Funny

      Same here. Although I tend to get into trouble for thinking with that noodle from time to time...

  10. Re:Matching images. by glueball · · Score: 2, Informative


    they're relatively easy to match up!


    Not always true. A GRE, SE, or FLAIR image sequence for anatomy will not line up well with the EPI sequence of fMRI due to B field non-linearities and shift even if the patient doesn't move. The nice thing, though, is that unless there is surgery and deformation due to swelling, tissue void, or skull shifting, the skull shape stays constant and one can use it as a rigid body for starting the registration.

    There are some software programs to attempt it but it still comes down to an expert setting some landmarks and using some validated software. Sorry, but the "free software" world is behind the commercial software and I see the gap widening.

    Bill

  11. Re:Matching images. by MillionthMonkey · · Score: 3, Informative

    Fortunately, most brains (unlike arms and legs) aren't in the habit of moving around a lot during an MRI scan, so they're relatively easy to match up!

    You've obviously never spent an hour inside one of those machines. I used to do research in an fMRI lab and even something like post nasal drip eventually makes you swallow just to keep breathing and the slight movement pushes your head into a new pixel lattice so when you subtract the images you just see gray everywhere.

  12. House by Elsapotk421 · · Score: 2, Funny

    great...now Dr. House will be ordering up a million of these on every episode.

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  13. 10 years ago by broothal · · Score: 3, Insightful

    "That is why I am excited about something that should have been here 10 years ago."

    It was. I actually wrote my master thesis about it exactly 10 years ago. But one thing is the technology. Another thing is someone to fund the development of a fully functional package. Technology is many years ahead of reality when it comes to medical imaging.

  14. Re:Not really a new thing by magbottle · · Score: 3, Informative

    > While it is good to see more talented people working in the medical visualization space,
    > this is not really a new thing. Image Fusion [wikipedia.org] has been around for a while now
    > but it has not yet become a mainstream technique.

    It is very mainstream for PET/CT fusion. Many manufacturers make combo PET/CT machines for just this purpose since the acquisitions are done at the same time, they align very closely and little if any rotation/translation has to be done for a good volume match.

  15. FYI,one way to compute 3d brain models from MRIs.. by syn1kk · · Score: 2, Interesting

    is done through the application of 'level sets' its pretty fun stuff to study. There are some cool videos of level set stuff like this one: http://graphics.stanford.edu/~fedkiw/animations/wa ter_oil.avi . And the application of level sets is very broad. I've only dabbled in Level Sets but I am very tempted to do a Master's thesis on it =P.