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Google Can Predict the Flu

An anonymous reader mentions Google Flu Trends, a newly unveiled initiative of Google.org, Google's philanthropic arm. The claim is that this Web service, which aggregates search data to track outbreaks of influenza, can spot disease trends up to 2 weeks before Centers for Disease Control data can. The NYTimes writeup begins: "What if Google knew before anyone else that a fast-spreading flu outbreak was putting you at heightened risk of getting sick? And what if it could alert you, your doctor and your local public health officials before the muscle aches and chills kicked in? That, in essence, is the promise of Google Flu Trends, a new Web tool ... unveiled on Tuesday, right at the start of flu season in the US. Google Flu Trends is based on the simple idea that people who are feeling sick will tend to turn to the Web for information, typing things like 'flu symptoms; or 'muscle aches' into Google. The service tracks such queries and charts their ebb and flow, broken down by regions and states."

55 of 289 comments (clear)

  1. Damn by tgd · · Score: 5, Interesting

    Thats a seriously great idea ...

    It totally sidesteps the problem of early symptoms not typically getting people to the doctor where it can potentially be reported/tracked.

    There's probably a lot of trends that can be detected the same way beyond just disease.

    1. Re:Damn by flyingsquid · · Score: 5, Funny

      Oh give me a break! I mean, assume for argument's sake that this technique actually worked. If it actually did, then the recent spike in search terms such as "mysterious virus", "flesh reanimation technology", "revivified corpses: control techniques" and "shotguns" on Google would indicate we're facing a major outbreak of zombies. That's just nonsense.

      I'd write more about why this idea won't work, but I'll have to do it tomorrow. Right now I've got a splitting headache, so I'm just going to put some neosporin on that bite I got from the weird guy on the subway train and then head to bed.

    2. Re:Damn by girlintraining · · Score: 5, Funny

      You have to break your query down by language and how old it is. See, looking for "massive zombie outbreak" won't get any results if, say, Russia gets overrun by the undead. I mean, what's Russian for "Oh sh*t we're all gonna die!" anyway? And given how often this happens, you really need to sort by date too. I mean, two weeks ago there was a major zombie outbreak. It happened all over the country, like some kind of national holiday. And then the next day everyone was all like "nuhhh--what happened? Where's the aspirin? BrrrrAAAAaaaaIIIiinNNNnnsss" Damn zombie boys... get your own damn brains. *sigh*

      --
      #fuckbeta #iamslashdot #dicemustdie
    3. Re:Damn by nizo · · Score: 5, Funny

      Yeah, because the first thing I am gonna think while running from a horde of zombies is, "Damn, I should go write a Slashdot journal entry about this".

    4. Re:Damn by Azkedar · · Score: 5, Informative

      Well, if you RTFA, you'll see that Google's method applied to the past four years very closely mathches trend data collected by physicians in coordination with the CDC. The proof is in the pudding.

    5. Re:Damn by Facegarden · · Score: 5, Insightful

      It doesn't predict anything reliably. Too many variables.

      Simply put: If you're looking for help online for flu symptoms, that doesn't correlate with an 'outbreak' of flu.

      And what defines outbreak anyway?

      Well, the way flu works, if you have it, you're likely to give it to someone else. You may google about it when you don't actually have it, but how often does that happen? The number of false positive searches would probably be somewhat low, and either way they would be constant. Google serves millions of search results a day, if not more. Almost everything "random" would, over time, look constant. When non-random things happen, like people from a certain region (remember, google knows your IP) getting the flu, even a 1% increase in flu related searches is extremely significant, if it otherwise doesn't vary that much.

      YOU googling for flu symptoms doesn't necessarily indicate if you have the flu, but a large increase in the number of people googling it probably does. Especially if you can compare your data to the CDC data, to check your theories.

      -Taylor

      --
      Worldwide Military budgets: $2100 billion. Worldwide Space Exploration budgets: $38 billion. Really, world? Really?
    6. Re:Damn by YrWrstNtmr · · Score: 3, Insightful

      Simply put: If you're looking for help online for flu symptoms, that doesn't correlate with an 'outbreak' of flu.

      If many, many others in your area are doing the same, it just might indicate a local outbreak.
      Graph this over time, and you might see trends happening.

      Do this for a couple of years, and compare to actual CDC data, and you might just find it works.

    7. Re:Damn by YrWrstNtmr · · Score: 4, Interesting

      True - if weren't for the pesky fact that the Google curves and the CDC curves differ significantly, and not just in lag time.

      Not according to the graph here

    8. Re:Damn by b4upoo · · Score: 4, Interesting

      What we are seeing is the edge of a very powerful, useful, and potentially deadly technology.Given a large enough quantity of data it is quite likely that correlations of seemingly unrelated data can be used as accurate predictors for other events. For example the price of eggs might be used to predict movement in the price of gold. Obviously that is overly simple but by using computational power and large data bases there should be methods found of predicting all kinds of things that may be world changing.

    9. Re:Damn by billcopc · · Score: 5, Funny

      I fail to see the sarcasm in your comment.

      --
      -Billco, Fnarg.com
    10. Re:Damn by syousef · · Score: 2, Insightful

      Well, if you RTFA, you'll see that Google's method applied to the past four years very closely mathches trend data collected by physicians in coordination with the CDC. The proof is in the pudding

      Exactly, which is why I'll be impressed when they can do this ahead of time. I'm not holding my breath. Analysing data trends in existing data and concluding you can predict them is not impressive.

      --
      These posts express my own personal views, not those of my employer
    11. Re:Damn by SleepingWaterBear · · Score: 3, Insightful

      Simply put: If you're looking for help online for flu symptoms, that doesn't correlate with an 'outbreak' of flu.

      I think you need to look up 'correlate' in a dictionary, you obviously have no idea what the word means. A correlation is not a one to one relation, if A correlates with B all that means is that A is more likely if B is true.

      Sure, the fact that i just went and searched for flu stuff out of curiosity doesn't mean there's an outbreak near me, but people presumably perform searches on this at a pretty steady rate, and a flu outbreak ought to cause a spike in searches. The occasional false positive happen in a region, say if there's a news story on the flu, but to say there's no correlation is ridiculous.

      You could I suppose argue that the correlation is too weak to pick out from the noise, however if you RTFA, it is quite clear that the correlation is quite strong enough to produce useful results.

    12. Re:Damn by Ihmhi · · Score: 3, Informative

      what's Russian for "Oh sh*t we're all gonna die!" anyway?

      According to Google, it's this. It translates from Russian back into English as this, which reads as "Well crap, we all will die!" I'd paste it here, but we all know how Slashcode mangles any foreign languages or special symbols.

      Oh, and I have no idea how I know this, but Russian for Brraaaaiiiiins is "Maaaassssgiiiiiiii".

      So really, if Russian zombies ever invade, some poor sap is just going to think it's a hobo saying "Musky" and they get bit.

    13. Re:Damn by tehgimp · · Score: 2, Informative

      The number of false positive searches would probably be somewhat low

      I don't disagree with the gist of your post. But having just finished a rotation of family medicine, I couldn't resist commenting.. the number of people who come into the doctor's office thinking they have the "flu", "strep throat" etc but have nothing more than the common cold is ridiculous. The number of false positives is alarmingly high.

    14. Re:Damn by IcyHando'Death · · Score: 4, Funny

      The proof is not, nor has it ever been, in the pudding. However perhaps you meant to say the proof (i.e. test) of the pudding is in the eating.

      Idiom police at your service. No, you needn't thank me ... just doing my job.

    15. Re:Damn by Gibbs-Duhem · · Score: 2

      Or, at least, it worked great until everyone started typing in "flu outbreak" in google to find the page they created!

      Second order effects, huzzah!

    16. Re:Damn by Sparr0 · · Score: 2, Informative

      If you watched the animation you would realize that the "general depiction of a rising and falling curve" is the point. The google prediction is two weeks ahead of the CDC data for the same changes, and can be data mined far more specifically for location and such.

    17. Re:Damn by vux984 · · Score: 4, Funny

      Yeah, because the first thing I am gonna think while running from a horde of zombies is, "Damn, I should go write a Slashdot journal entry about this".

      Good point. But you can bet your ass that the twits on twitter will be tweeting...

      "Zombies in the street. Gonna stay in tonight." ...
      "Garbage stinks... better take it out."...
      "it bit me. Hertz pretty bad." ...
      "Man TV sucks on Monday night. Watching Simpons reruns." ...
      "Seems cold in here. Crankin the heat."...
      "I'm so hungry...lets see whats in the kitchen...!"
      "Hand ii coodaafination fafading.. fafegae"...
      "need bwrainsss brAaainzzs...."

    18. Re:Damn by GooberToo · · Score: 4, Insightful

      That's why we have a "flu season." It is very cyclic in nature. Trends will very likely be a good indicator when localized spikes of new queries provide a precursor where a previous trend can further enforce.

      In other words, a spike of localized searches related to flu falling well within flu season for a given geographic locale, likely is a precursor to a growing flu outbreak. It's really not that hard to imagine - especially once you consider the incubation time of your typical flu virus.

      The lead time prediction of Google's method verses the CDC's post-suffering reporting is easy to guess. The CDC's numbers measure reported cases. Google's method measures localized interest (signal), develop a metric to discern against baseline interest (noise), and apply against trend data (signal has velocity), you likely have identified a growing flu outbreak. Once you add the incubation time, it's likely Google's numbers have a strong correlation with the reported CDC numbers.

    19. Re:Damn by drinkypoo · · Score: 2, Funny

      "Hand ii coodaafination fafading.. fafegae"...
      "need bwrainsss brAaainzzs...."

      And these are different from normal twits (best ever name for twitter entries) how?

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
    20. Re:Damn by drinkypoo · · Score: 2, Insightful

      The CDC charts reported flu cases. Flu cases are only reported if you seek medical care. If you just go to the drug store and buy a bottle of NyQuil, the CDC doesn't know you had the flu. I should not have to tell you this...

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
  2. So, if you want to game the system... by jcr · · Score: 4, Insightful

    Buy stock in companies that sell treatments for Beri-Beri, Trench Foot, and Jungle Rot, and then have your botnet look them on on google.

    -jcr

    --
    The only title of honor that a tyrant can grant is "Enemy of the State."
    1. Re:So, if you want to game the system... by TubeSteak · · Score: 2, Interesting

      Buy stock in companies that sell treatments for Beri-Beri, Trench Foot, and Jungle Rot, and then have your botnet look them on on google.

      I had thoughts along the same line, but in a different direction after reading this quote FTFA:

      "And internally [Google] has tested the use of search data to reach conclusions about economic, marketing and entertainment trends."

      If Google can correlate search terms with movements in stock or commodities markets, they might be able to attain that precious first mover advantage

      --
      [Fuck Beta]
      o0t!
  3. future Google services by bmecoli · · Score: 5, Funny

    In the future, Google will be able to record your eating habits and predict when you are going to poop.

    This, of course, won't work on female users since we all know that girls don't poop.

    1. Re:future Google services by girlintraining · · Score: 5, Funny

      yes we do, we just don't make a damn production out of it by telling everyone, then doing it and acting like setting off the smoke alarm gives us extra credit.

      --
      #fuckbeta #iamslashdot #dicemustdie
    2. Re:future Google services by mpoulton · · Score: 4, Funny

      Setting off the smoke alarm DOES give you extra credit. That kind of attitude is why girls never win at pooping.

      --
      I am a geek attorney, but not your geek attorney unless you've already retained me. This is not legal advice.
    3. Re:future Google services by girlintraining · · Score: 2, Funny

      Men compete over the stupidest shit. Literally.

      --
      #fuckbeta #iamslashdot #dicemustdie
  4. Madagascar Closes Down by jon_cooper · · Score: 5, Funny

    If Madagascar detects anyone googling "flu" they'll close their ports.

  5. Can slashdot cause flu? by WarJolt · · Score: 4, Insightful

    Do to the /. effect thousands of /.ers started googling flu symptoms causing the predictor to indicate a flu outbreak.

    Thousands of hypochondriacs responded by checking themselves into hospitals complaining about flu-like symptoms.

  6. Re:Great. by mpoulton · · Score: 4, Informative

    If you've received a flu shot in the past 6 years the only thing you got was a chance at a bad immune reaction and a concoction of mercury, detergent and some other nasty compounds.

    That's blatantly untrue. The flu strain predictions have been fairly good in the last few years, with the exception of 2003-2004 when it was only marginally protective for one of the more common strains. Even that year, it was largely protective for most strains. Get your damn flu shot and protect the rest of us. For reference:
    wikipedia

    --
    I am a geek attorney, but not your geek attorney unless you've already retained me. This is not legal advice.
  7. Re:Great. by Cyberax · · Score: 4, Informative

    Umm...

    You're TOTALLY wrong. WHO-recommended flu vaccines are very effective. See here for an example: http://www.phac-aspc.gc.ca/publicat/ccdr-rmtc/06vol32/acs-07/index.html

    And: "...the only thing you got was a chance at a bad immune reaction and a concoction of mercury, detergent and some other nasty compounds..." is just a stock anti-vaccination quackery.

  8. Finally, a get rich scheme that will work! by nilbog · · Score: 4, Interesting

    1. Invest in Tamiflu (the leading medication to treat flu symptoms)
    2. Organize a massive effort to do web searches for "flu symptoms"
    3. Wait for Google to sound the flu alarm
    4. Profit!

    --
    or else!
  9. Trend data as a long term resource by dada21 · · Score: 4, Insightful

    As a capitalist, and an incubator, I've spent tens of thousands of dollars (per project) on market analyses. For me, finding if a particular good or service, even a niche or very specific on, is desired in a given area is expensive. It's often the MOST expensive thing I do before starting a business.

    I've always harbored the idea that Google's grasp of data, even just raw data, is their most important resource. As they make this information available, the market will prosper. I've been able to use Google Trends (national, not local) to profit from the so-called "long-tail" and enter a business market I might otherwise not have.

    When Google starts making trend data available based on region, it will be a huge boon for guys like me -- the risk takers. I'd love to know if a certain term is growing in popularity in given regions, or even in given regions at certain times (say "Where can I get vegan food?" in Chicago after 10pm but before 4am). I'd love to know if it's from a desktop or mobile, or even a Mac versus PC. By digging deeper into a customer-base's desire, Google trending can offer me a profitable business, but it can also offer the customer base more competition (or even a product that isn't readily available in their market).

    The flu trending is just an eyewash to push Google's strength in raw data retention over time. That's their reason for doing it. Will it help people? Certainly. But to those anti-capitalists, this is exactly where capitalism reaches those in need, but still can provide a profit for the charitable person or company.

    1. Re:Trend data as a long term resource by Detritus · · Score: 2, Insightful

      ...and the difference between the two is what? As a non-Christian, I'm not too impressed with the morality and ethics of Christian business people, or of business people in general.

      --
      Mea navis aericumbens anguillis abundat
  10. Re:How long until... by evanbd · · Score: 3, Insightful

    A very long time. How on earth is this "interesting?" Is crazed paranoia on /. really the most interesting thing you've seen all day? I think some of the mods need to get out more.

  11. Re:So? by justinlee37 · · Score: 5, Informative

    You obviously haven't heard much about The 1918 Flu Pandemic

  12. I had a similar idea.... by Brad1138 · · Score: 3, Interesting

    5-10 years ago I had a somewhat similar idea:

    We all know that animals act odd, hours or days before things like earthquakes. The morning before a 6.8 quake in Washington State in 2001, my neighbors dog that normally will do anything to force it's way out of the front door and run for hours when the door is opened the slightest bit, wouldn't even get close to the door when the neighbor opened it. By itself, 1 animal acting weird means nothing, but a large group of animals over a localized area acting weird at the same time would point to something about to happen. The problem is that it is always after the "catastrophe" that people say, "You know sparky was acting odd this morning". If there was an online database that you could quickly go to and report that at your address your pet is acting weird at this moment, you might be able to predict the event by looking for groups of "odd acting" pets. I know it seems like a weird & far fetched idea, but tell me why it wouldn't work.

    --
    If you could reason with religious people, there would be no religious people
    1. Re:I had a similar idea.... by jrumney · · Score: 3, Insightful

      Dogs and other animals do random things that might seem a little odd all the time. Most of the time, you don't give it a second thought, but when something unpredictable happens, like an earthquake, if you believe in the supernatural powers of dogs, then you might connect the random odd acts with the earthquake after the fact, in much the same way that plagues of locusts and floods get connected with the actions of people leading up to their occurrence, and ascribed to "punishment from God" in the bible.

  13. Re:Great. by YesIAmAScript · · Score: 3, Informative

    If you've received a flu shot in the past 6 years the only thing you got was a chance at a bad immune reaction and a concoction of mercury, detergent and some other nasty compounds.

    Thimerosal (mercury) is only used in multi-dose vials. Although these are legal in the US, they are in practice not used here. The chances you received any thimerosal in your flu shot if you got in the US is almost nil.

    I do agree with the OP that two years of the last decade the WHO predicted which strains would be dominant in the US incorrectly and thus the shot didn't immunize the recipient properly against the strains they would actually face.

    --
    http://lkml.org/lkml/2005/8/20/95
  14. Re:Not a very reliable metric. by girlintraining · · Score: 3, Interesting

    Yes, but not without violating the privacy of the users of google. We don't ask for their personal information from the clinic because it's a privacy violation, but we apparently have no moral objections to using their browser histories to get pretty much the same data.

    --
    #fuckbeta #iamslashdot #dicemustdie
  15. Re:Great. by Anonymous Coward · · Score: 2, Interesting

    You're TOTALLY wrong. WHO-recommended flu vaccines are very effective

    You're correct, for the majority. There are those of us though who end up having immune system reactions for a good month to 6 weeks following a flu shot every single time.

    I specifically do NOT get a flu shot for this reason, but if one does not have this kind of reaction then you're exactly correct. I may not be a carrier with the vaccine but i cannot risk being guaranteed under the weather for almost 10% of the year as opposed to the risk of possibly contracting the flu during the winter myself.

    The following is more of a way the hell out there probability:
    There is the other side of the coin that we have yet to get a long term enough sample set to verify. Imagine a world where humanity has been vaccinating for a few generations and suddenly due to one event or another, the supply of vaccines is no longer available.

    I hope those practice runs on the vaccines is enough to keep our immune systems able to cope. The chances of vaccination having a negative effect on us being naturally able to cope with new strains is a non-zero to keep an eye on if nothing else. Not saying OMG FLU SHOTS EVIL EACH INNOCULATION KILLS A KITTEN or anything, but theres a lot of outliers like this that many people avoid considering. Personally i think it has a lot to do with the years of grooming patients to accept a doctor as god as opposed to another human, with all the possible error conditions that applies, who happens to know a shitload about medicine and biology.

  16. Re:Great. by Irish_Samurai · · Score: 3, Interesting

    Just an aside.

    How the hell does WHO predict Flu strains for immunization? I am honestly ignorant and would like to know.

  17. What Else Can They Predict? by Fuseboy · · Score: 2, Interesting

    This is fascinating, but it does make me wonder what else they could be predicting.

    For example, if they're correlating searches from at-work employees, I bet they could turn up all manner of interesting things - predicting layoffs or other adverse business conditions, see who HR is googling (are they interviewing Google employees?).

    Or keeping tabs on start-ups that are doing research into areas that Google is looking to make acquisitions. (Imagine when you're trying to sell your company to Google, they pull your employees' search history to see how long you've really been working on your flux capacitor.)

  18. Re:So? by hldn · · Score: 3, Funny

    everyone knows it starts in arnette, tx.

    --
    http://www.accountkiller.com/removal-requested
  19. Re:Great. by niw · · Score: 2, Interesting

    While the healthy won't die or have any serious consequences, they can still pass it on the others, who may be a greater risk.

  20. Re:So? by theraptor05 · · Score: 3, Informative

    ....Penicillin is an anti-biotic. Not going to do a thing against the flu. About the only development that has helped us fight the flu is vaccination. And maybe a small bit of improvement in personal hygiene.

  21. The Technique Works by broward · · Score: 3, Interesting

    I posted models of it almost three years ago.

    http://www.realmeme.com/Main/dailymeme/2005/Aug/coughcoldDejanews.png

    Web searches are co-incidental indicators.

    Want to see something that Google hasn't shown you?

    http://www.realmeme.com/roller/page/realmeme/?entry=sars_versus_avian_flu_meme

    It's quite likely that the Internet retains knowledge and alters its behavior over time. Compare the group reaction time between the SARS and avian flu viruses.

  22. Guys named, Dick Drop. by Ostracus · · Score: 2, Funny

    "That, in essence, is the promise of Google Flu Trends, a new Web tool... unveiled on Tuesday, right at the start of flu season in the US. Google Flu Trends is based on the simple idea that people who are feeling sick will tend to turn to the Web for information, typing things like 'flu symptoms; or 'muscle aches' into Google. The service tracks such queries and charts their ebb and flow, broken down by regions and states.""

    Hmmm. *types in Google "Dick falling off"*

    --
    Shai Schticks:"You don't make peace with friends, you make peace with enemies"
  23. Re:Great. by KevinIsOwn · · Score: 3, Interesting

    What a ridiculous statement. Yes, viruses and bacteria mutate, but a vaccine is a good way of fighting it. Small pox didn't suddenly get worse when everyone got vaccinated, on the contrary, it was pretty much eradicated, save for lab samples. Vaccines have made a number of diseases practically unknown to the modern world thanks to their incredible effectiveness (polio anyone?), and here you are spreading completely wrong information about vaccination.

    A realistic assessment of the flu vaccine can pretty easily show its value- it's around 60-70% effective, according to the sheet they gave me when I got vaccinated this year. If a majority of the people you come in contact with are vaccinated, it clearly reduces the probability of infection. This becomes especially important if you plan to visit anyone in a nursing home or hospital, in terms of protecting them as well as yourself from the flu.

    So stop trying to out-think the logic of vaccination just to be different and go get vaccinated. It won't hurt you, it doesn't cause autism, and you won't turn into a zombie (and even if you do, brains may just be pretty tasty)

  24. Re:Great. by KevinIsOwn · · Score: 2, Insightful
    Why don't you stop posting your accusations of brainwashing and realize you are getting modded to oblivion because you are wrong. 100% wrong. I already responded to one of your other comments linking that crappy video and website, but I'll respond to more of your comments just because I feel like feeding the trolls today.

    Any independent research will show that the only people claiming a benefit from flu shots are either profiting, or governmental organizations.

    How about all the people who haven't gotten smallpox? How about the people who haven't been crippled from polio? Or maybe the people who have avoided tetanus, measles, mumps, and rubella?

    Oh right, you forgot about all of those people, even though that pretty much describes everybody.

  25. Self defeating? by Culture20 · · Score: 3, Interesting

    So, if people start relying on google warnings, two things will result: Increased searches for "flu symptoms" after a google warning (increasing the size and scope of a warning), and almost no searches for "flu symptoms" when no warnings are issued (reducing the frequency of the warnings).

  26. Syndromic Surveilance by Rorschach1 · · Score: 2, Insightful

    This sort of thing has been floated around for a while under the banner of 'syndromic surveilance'. I spent most of the last three years working on a research project that involved gathering data on water quality and developing statistical software to find subtle indications of contamination. The intent was always to extend the approach to syndromic data, incorporating things like over-the-counter medicine sales, ER visits, and so forth.

    Unfortunately, it turns out that none of us on the team knew enough about statistics to manage a fantasy football league. I'm now happily self-employed doing stuff absolutely unrelated to statistics. I think some of my hair has grown back, and I hardly even cringe when someone says 'generalized least squares'.

    If you're interested, though, here is a paper from the CDC on the subject. I'm pretty sure they have a better idea what they're talking about. Or at any rate, they've got nicer graphics.

  27. Re:Great. by thepotoo · · Score: 3, Interesting
    Since you don't have any replies yet I'll give it my best shot.

    Influenza (the flu), originates in China pretty much every year. Different strains of RNA viruses arise (mutations in antigens, the process is called antigenic drift), in pigs. These are different enough to be able to get past the immune system (which is resistant to last year's strain, but unable to recognize recombined (new) antigens).

    Pigs share a common receptor with people which is hijacked by these RNA viruses; this allows the virus to jump from pigs to humans. (Aside: they also share a different receptor with birds, which is why we're so paranoid about avian influenza: it could jump to pigs, mutate to our receptor, and then jump to humans.)

    Every year you'll have dozens of different strains of influenza arising in pigs; only and handful of these use the common receptor and are able to jump to people. From there, only a handful of these are spread (through migration) to other parts of the world. IIRC, the flu spreads west with the climate, eventually encountering a city where it's able to hitch a ride to America (and the rest of the world) on a boat or an airplane.

    WHO relies on being able to look at previous strains which reached epidemic and pandemic proportions, and on being able to artificially recombine antigens to create this years major strains. Sometimes they miss a few critical ones (2003-2004), but they're remarkably good about predicting which strains will mutate.

    Basically, there are only a few different antigens, and we rely on creating the same new set that nature will create (there's a finite number of viable recombinant strains, after all). I doubt they look at pigs in China; there's simply too many in areas that are too remote.

    If there's an epidemiologist reading this, he can probably give you a more detailed answer.

    --
    Obligatory Soundbite Catchphrase
  28. Amazing by DiadoMraz · · Score: 2, Funny

    That's great! Google strikes again... We can now "predict" a flu season when it is already happening. The timing of a flu season is more or less regular for a particular place (one of the mysteries of flu) and the big problem is not to predict when it will happen, but what will be the strain of choice for this year. This is the effort of CDC/WHO and it is a tricky problem because the flu virus mutates a lot (hence the need to be vaccinated every year). The mutation sometimes is such that an avian and a human virus combine to produce a new human virus. That's when bad things happen (predicted vaccines fail, 1918 pandemic, etc.). Google's idea is at best very interesting as a tool for monitoring the spread of flu amongst people with access to internet, but I fail to see its predictive power in general.

  29. Re:Great. by Vornzog · · Score: 2, Informative

    How the hell does WHO predict Flu strains for immunization? I am honestly ignorant and would like to know.

    No magic, really.

    Basically, they pick the dominant strain that is circulating at the time that they have to make a recommendation to the vaccine producers.

    The vaccine strain has to be picked ~6 months before it is needed (it takes that long to grow it up in eggs in sufficient quantity). Typically, that is right at the peak of flu season for the other hemisphere (north/south).

    The selection is based on the RNA sequence for the virus, and on antigenic tests (antibodies to the strain, grown up in ferrets usually).

    The selection is made much earlier than the CDC/WHO would like, but the long lead time for vaccines means you have to do it. So the track record for picking vaccine strains the last few years is pretty remarkable.

    The only 'wrong' strain that got picked was the H3N2 strain in 2003. Everyone knew which strain to pick, but they couldn't make it grow in eggs. So they picked another one that did grow (better than nothing) and a lot of people died. Since then, there has been a lot more interest in getting a cell-based vaccine pushed through the FDA here in the US...

    --

    -V-

    Who can decide a priori? Nobody.
    -Sartre