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Believing In Medical Treatments That Don't Work

Hugh Pickens writes "David H. Newman, M.D. has an interesting article in the NY Times where he discusses common medical treatments that aren't supported by the best available evidence. For example, doctors have administered 'beta-blockers' for decades to heart attack victims, although studies show that the early administration of beta-blockers does not save lives; patients with ear infections are more likely to be harmed by antibiotics than helped — the infections typically recede within days regardless of treatment and the same is true for bronchitis, sinusitis, and sore throats; no cough remedies have ever been proven better than a placebo. Back surgeries to relieve pain are, in the majority of cases, no better than nonsurgical treatment, and knee surgery is no better than sham knee surgery where surgeons 'pretend' to do surgery while the patient is under light anesthesia. Newman says that treatment based on ideology is alluring, 'but the uncomfortable truth is that many expensive, invasive interventions are of little or no benefit and cause potentially uncomfortable, costly, and dangerous side effects and complications.' The Obama administration's plan for reform includes identifying health care measures that work and those that don't, and there are signs of hope for evidence-based medicine: earlier this year hospital administrators were informed by the Centers for Medicare and Medicaid Services that beta-blocker treatment will be retired as a government indicator of quality care, beginning April 1, 2009. 'After years of advocacy that cemented immediate beta-blockers in the treatment protocols of virtually every hospital in the country,' writes Newman, 'the agency has demonstrated that minds can be changed.'"

22 of 467 comments (clear)

  1. And next up by m0s3m8n · · Score: 5, Interesting

    Just wait. Next up will be treatment based on life expectancy and quality. I see this becoming an issue based on my experience working for a group of Eye docs (retinal specialists). I often see very elderly (and often demented) patients receiving very expensive treatment of eye conditions. do they need the treatment - sure, to preserve their sight. Does the treatment improve their quality of life - maybe. So who decides, the patient or family, or BIG government?

    --
    Conservative, mod down for violating /. political norms.
    1. Re:And next up by JohnFluxx · · Score: 4, Interesting

      The scientist in me likes the ideas of NICE. If an operation neither extends life nor increases quality of life, then what's the point in the operation?

      Of course, it never works perfectly, but I'd be interested in what the critisms against NICE are?

    2. Re:And next up by b4upoo · · Score: 1, Interesting

      I can testify that knee surgery is sometimes a wonderful cure. I suffered terrible pain for years and two new artificial knees are better than the originals in many ways and they never,ever hurt at all.

    3. Re:And next up by stonewallred · · Score: 2, Interesting

      Just 10k a year. Wow, that's cheap. Let me look at my 1000.00 dollar a month budget and figure out how to work that in. 475.00 rent 50.00 car insurance 41.00 internet (college student with both campus and on line classes) 30.00 a week gasoline 55.00 a week grocery bill 50.00 cell phone oops, run out of money How about you sending me the money to afford health insurance since it is such a small amount in your world?

    4. Re:And next up by wisty · · Score: 2, Interesting

      It's more like an all-you-can-eat restaurant analogy situation than a car analogy situation. Some idiot will always pig out on the lobsters and oysters, even if it makes them sick. Doesn't matter whether it's private or public insurance, people will abuse the system.

      More doctors and nurses can be trained (provided that they have hospitals to train in), and more hospitals can be built (as long as there are doctors and nurses to staff them). MRI machines can be built, just like cars.

      We are only at the limit of how many surgeries can be performed because demand is not price sensitive. People getting the treatment don't care what it costs, because the health insurer (or government) is paying.

  2. Goes to show. by palegray.net · · Score: 5, Interesting

    The human body is pretty darn good at healing itself. There is absolutely no replacement for a decent diet, moderate exercise, and a positive attitude. The last factor alone has been repeatedly shown to boost immune system health over a variety of drug-based treatments.

    1. Re:Goes to show. by Hurricane78 · · Score: 2, Interesting

      I'd say in fact, especially for us people who like tinkering and tuning complex machines, getting our body to run perfectly should be a pretty easy and fun thing to do.
      The them "species-appropriate" is the key word. What is the perfect food for our machine called body? How do you maintain it? How does the brain work?

      If you look that stuff up, it all becomes so totally obvious. And much simpler to implement.

      About the last factor: What you mean is the placebo effect. There were experiments, where people became real swellings, from imagining a bee sting alone. This is still some mechanism that is not fully understood. But I think we can control more of our body trough our mind, than we think. Even optimize our healing.

      --
      Any sufficiently advanced intelligence is indistinguishable from stupidity.
    2. Re:Goes to show. by JWSmythe · · Score: 2, Interesting

          You're amazingly correct.

          I tell kids, pain is in their head. The sensory impulses tell the brain "this happened". Without the brain processing the input, it never happened.

          Take a kid who just tripped and banged something. Distract them from the pain. Tickle them. Poke them in the arm. Some people just yell "Hey, stop crying!". It distracts them from the pain, and it's either meaningless or just doesn't hurt as bad.

          I've sure you've heard of people who have walked on broken legs, because either they had to, or they were stupid. Sometimes you'll read stories of athletes and druggies doing that. They ignore the pain (mentally, or chemically), so it doesn't exist. Some people meditate. I just focus on ignoring the pain, by focusing on something else.

          Years ago, I cut my leg pretty badly. I could have cried over it. Instead, I gathered supplies to clean and protect the wound. When I poured alcohol on it, the people around me flinched, but I didn't. A few said "Ouch! Doesn't that hurt?!" Sure it hurts, but I was focused on cleaning the wound, rather than thinking about it. It wasn't that bad. About 3" long, 3/8" deep, and had spread 3/8" wide. I had to ask for help pinching it shut, so I could bandage it properly. I've seen people with papercuts scream more, and they weren't bleeding. I prefer to focus on what has to be done, rather than what is wrong. Then I can observe what else is happening.

          I'm not a warm fuzzy meditative holistic nut, that'll drink tea and fruit juice to make the world a better place. I do like to understand the human body, which is an amazing collection of parts, with a little something more that makes us alive. Well, alive if you're reading this. :)

      --
      Serious? Seriousness is well above my pay grade.
    3. Re:Goes to show. by lawpoop · · Score: 4, Interesting

      I think that the human organism basis some of its healing on its perception of its role in society. We are a social creature. Every culture has some kind of 'theory of medicine' -- that disease has a cause, which can be treated by certain practices, procedures, and bitter plant concoction ( the taste of 'bitter' is the chemical recognition of alkaloids, or drug compounds, in a plant ).

      If we are receiving 'treatment', or attention from the community when we are known to be sick, then our body's healing response will amp up.

      Likewise, people can die basically 'on command' in certain circumstances, when a doctor or sorcerer pronounces them dead. In some tribe somewhere, if a shaman does a certain ritual called a 'bone-pointing', the person who gets cursed will sicken and die in about three days -- shorter than you would die from thirst or hunger. Likewise, back in the 80s when AIDS was first on the scene, people would sometimes die within days of a diagnosis. Doctors didn't find any physical cause; they just kind of willed themself to death, probably because of the severe social stigma and lack of hope that an AIDS diagnosis meant at that point.

      So I think placebo medicine will be a big insight into understanding human health in the future.

      --
      Computers are useless. They can only give you answers.
      -- Pablo Picasso
  3. Inefficiency by syntaxglitch · · Score: 4, Interesting

    It's well-established that Americans as a whole pay far too much for health for far too little benefit, compared to other first-world nations.

    Can some of this discrepancy be explained by high availability of essentially useless or even harmful "treatments"?

  4. Sinusitis by jonpublic · · Score: 5, Interesting

    My experience with sinusitis definitely confirms this. Every 3 months or so I would come down with another sinus infection. Each time I would goto the doctor and get a prescription for antibiotics. I wasn't asking for antibiotics. I was looking for a solution to the problem. One time the doctor wanted me to switch to a much more expensive antibiotic. Sure enough I ended up getting some nerve damage from the antibiotic. Nothing permanent, but the numbness lingered for over a year.

    What the kicker here is that if the doctor had looked at my chart and said, maybe we should take another approach after the 5 or 6th time, the whole situation would have been avoided.

    I got a neti pot and I haven't had a sinus infection since, I just use the neti pot whenever I feel my head getting clogged up. $20 dollar solution.

  5. Beta Blockers by jamesl · · Score: 2, Interesting

    On the other hand, generic beta blockers (ie. propranalol) are so cheap as to be almost free. The conclusion in the cited article does not call for an absolute ban on beta-blocker therapy: Consequently, it might generally be prudent to consider starting beta-blocker therapy in hospital only when the haemodynamic condition after MI has stabilised.

    As much as we would like to believe otherwise, medicine is still an inexact science.

  6. Idiotic. by DrYak · · Score: 5, Interesting

    Every 3 months or so I would come down with another sinus infection. Each time I would goto the doctor and get a prescription for antibiotics.

    This is indeed idiotic. You should shot your doctor. There's plenty of evidence that chronic sinusitis aren't caused by bacteria (the only thing killed by antibiotics).

    If the doctor really wanted to try something, he should have made a try with an anti-fungic (some studies tend to show that part of recurring sinusitis might be due to bugs more of the fungi persuasion).

    I got a neti pot and I haven't had a sinus infection since, I just use the neti pot whenever I feel my head getting clogged up. $20 dollar solution.

    Brilliant. Washing the nasal cavity is a method which also works for viruses which you most likely had like most of the adult population (and against which antibiotics are no use).
    It's part of what we prescribe here around (although as I said in another post, I now work in research).

    For extra, you can also buy sprays containing carbocisteine (an agent helping making the mucus more fluid), but you should use sprays containing beta-mimetics more than 1-2 weeks.

    But the basic "clean the cavity with water" $20 solution works too.

    --
    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
    1. Re:Idiotic. by nine-times · · Score: 2, Interesting

      If the doctor really wanted to try something, he should have made a try with an anti-fungic (some studies tend to show that part of recurring sinusitis might be due to bugs more of the fungi persuasion).

      But that would be more work and would not help the doctor any more in what he's really trying to do: get the patient out of his office.

      Seriously, I'm amazed at how lazy most doctors are about actually trying to help their patients, considering how much work it takes to get to be a doctor. I would bet money that none of my doctors in my adult life have bothered to look at my file a single time except when I've been in their presence. As in, I come with symptoms, and when I'm in the office they grab my file. They glance at the file while I tell them my symptoms, and then they recommend the first course of treatment that pops into their heads.

      If they don't know what the problem is, they don't delve further into my file. They don't go back and research the situation. They don't try to contact other experts to look for greater insight.

      When I was working helpdesk, if I had been that lazy in trying to diagnose problems, I would have been fired.

  7. Pressure system by dov_0 · · Score: 2, Interesting

    Unfortunately medicine, just like any other industry is driven by profit.

    Eli Lily pushed Prozac and got it approved in many countries even though it causes psychotic episodes in 18% of patents. They even send sample packs to GP's so they can hand them out to patients. Psychiatry in itself is a whole sham, pushing drugs which will never heal the patient, when in many cases counseling or Cognitive Behaviour Therapy will bring about a cure.

    Myself, I used to have terrible problems with allergies and get awful migraines. Once I stopped taking pain-killers and antihistamines the problems largely abated. Haven't taken anti-biotics in 13 years and I reckon I get over any nasties I catch mor quickly than I used to. Very rarely get sick though!

    The amount of useless drugs administered and useless surgery performed won't go down while there's money to be made. The pressure will always be on the medicos. Either from the drug companies or for the payments on the new sports car.

    --
    sudo mount --milk --sugar /cup/tea /mouth /etc/init.d/relax start
  8. Re:patients are just customers by nelsonal · · Score: 3, Interesting

    In a similar vein, there are some recent studies that suggest that most of the benefit of medicine is the temporary status transfer from a high status individual paying more attention to the patient which perversely causes them to get better. That goes along with the idea that it's important to get your chance to get that status boost.

    --
    Degaussing scares the bad magnetism out of the monitor and fills it with good karma.
  9. PayWall by jamesl · · Score: 2, Interesting

    Perhaps if The New England Journal of Medicine was available free on-line, more patients would know about the conclusions of the cited article Spinal-Fusion Surgery -- The Case For Restraint. Access to the single article costs $10.

  10. Corrupt Doctors by bloobamator · · Score: 4, Interesting

    The single biggest factor driving health care costs in America is the corruption of doctors. Too many doctors are on the take from Big Pharma.

    I personally know one who makes millions dispensing medicines pushed by the pharmaceutical companies. He owns a big house in the Westchester, a swank apartment on the Upper East Side, 2 BMW's, a Mercedes, pays hefty child support, alimony (which includes a third mortgage on his ex-wife's big house in Westchester), and he parties like a freak.

    He's not even a surgeon. How does he make so much money? By accepting kickbacks from the pharmaceutical companies for the medicines he prescribes and dispenses (his specialty allows him to dispense certain injections to relieve back pain.)

    All this guy does is inject people's backs with something that is clearly ineffective, and then refers them on to his surgeon buddy when the injections don't work. What a scam!

    He bragged to me on several occassions, while drunk, how the Big Pharma companies wined and dined him in super-expensive Manhattan restaurants, and how they paid for ultra-luxurious island vacations. I know there was more he wasn't telling me.

    I met another "doctor" who actually just owned a bunch of clinics in NJ. He was the dumbest son-of-a-bitch I have ever met, and he walked, talked and dressed like a wiseguy. Yet he drove 2 Rolls-Royces and invested heavily in porn sites and strip clubs in FL. He was scary, really scary, yet he was a "leader in quality private health care in the greater NJ region". *shiver*

    It's time we cracked down on medical waste and fraud.

    --
    "Crude and slow, clansman. Your attack was no better than that of a clumsy child."
  11. Ear infections TYPICALLY recede in a few days? by Kral_Blbec · · Score: 4, Interesting

    So what about those that dont? When I was a kid, our doctor refused to give me anything based on this reasoning. As a result of chronic untreated ear infections, I developed a speech impediment that i had to have therapy for until i was almost 16 and still lingers today. I attribute a lot of my anti-sociality in my youth (and now) to being embarrassed to talk. Thanks for nothing doc.

  12. Rapid CRP by Aggrajag · · Score: 3, Interesting

    At least here in Finland it is common practice to take a rapid CRP test from patients when they show symptoms of for example sinusitis. If the result is less than 10 sinusitis is most likely caused by a viral infection so no antibiotics will do the patient any good.

  13. it is about money. by Organic+Brain+Damage · · Score: 2, Interesting

    The numbers are somewhat astonishing, last I heard it was like 14% of GDP going into healthcare in the USA.

    If we look at unnecessary procedures like the arthroscopy for osteoarthritis (assuming the study results are repeatable) that's one major way to save money.

    Another major way to save money is to make the payment handling a non-profit business. Something like 20% of healthcare spending is going into the insurance business and dealing with payments. That should be more like 2%.

    And a third major savings is to be gained by realizing we're all going to die and not spending huge money on someone in their last six months. It makes no sense, but most of the money spent on most of the people in the USA is spent on people within 6 months of death. And most of the time, their life is no longer than if they didn't spend the money, but it is more painful. Curbing this spending could save us as much as 20% of our current healthcare spending.

    I suggest that if a person is 2 years beyond average lifespan, no government money be spent on hospitalization or surgery. If they have the money to buy private insurance or can pay for it out of pocket, fine, that's their choice, but otherwise, too bad, don't make the rest of us pay for torturing your granny to death.

  14. Re:This isn't news... by WayneTheGoblin · · Score: 2, Interesting

    Actually, while I'll agree with you that the latest research doesn't support any prophylactic effect from taking vitamin C for colds and the like, I'm going to disagree with your conclusion.

    Vitamin C does have a number of effects that make it worth taking during a cold or flu. Biochemically, vitamin C has a number of roles, such as deactivating histamine, which is one of the causes of feeling sick when you're sick, and it plays a major role in free radical clean up.

    When you're sick, your immunocytes are attacking the invading pathogen with such wonderful enzymes as myeloperoxidase, which take hydrogen peroxide (produced in the oxidative burst) and turn it into HOCl (bleach) in order to kill the pathogen. This process spews reactive oxygen species (free radicals). When the ROSs interact with your cells, they cause damage, which leads to cytokine release and mast cell degranulation. Mast cells are the primary histamine releasers. So, not only is Vitamin C involved in the cleaning up of free radicals (in that vitamin C will quench the free radical, by itself becoming a free radical, albeit a safer and more stable one), but it also deactivates histamine.

    Additionally, if you'd care to do the research, most of the studies showing megavitamin therapy (in the case of vitamin C) to be ineffective have either been performed by those with an interest in showing that it's ineffective (i.e. the drug companies), or had indeterminate conclusions.

    Much more research needs to be done on the subject, but since the only problem with (oral, at least) vitamin C therapy seems to be osmotic diarrhea at more than 2g/day intake, in my opinion, there is no reason not use it for this purpose.

    IAAMedStudent

    --
    I refuse to engage in a duel of wits with the unarmed.