Scientists Create RNA From Primordial Soup
Kristina at Science News writes "The RNA world hypothesis proposed 40 years ago suggested that life on Earth started not with DNA but with RNA. Now a team of scientists bolsters this hypothesis, having assembled RNA in the lab from a mixture that resembles what was likely the primordial soup. 'Until now,' Science News reports, 'scientists couldn't figure out the chemical reactions that created the earliest RNA molecules.' The new work started the RNA assembly chemistry from a different angle than what earlier work had tried."
I thought that the headline was "Scientists Create RNA From Primordial Soap", which would have been interesting in a completely different way.
Nothing for 6-digit uids?
Abiogenesis.... Take that ID-iots!
Ahhh...the great dumpster continuum. Many a free computer will be found there. -- sowth (748135)
Primordial Post!!!11!one!one
You failed. Try again in another 3.8 billion years.
with extra croutons!
I'm a rabbit startled by the headlights of life
A wizard did it.
That they accidentally got RNA and thought they created it themselves? Did you read the article?
âoeBut while this is a step forward, itâ(TM)s not the whole picture,â Ferris points out. âoeItâ(TM)s not as simple as putting compounds in a beaker and mixing it up. Itâ(TM)s a series of steps. You still have to stop and purify and then do the next step, and that probably didnâ(TM)t happen in the ancient world.â
Sutherland and his team can so far make RNA molecules with two different bases, and there are still another two bases to figure out.
Beware: In C++, your friends can see your privates!
they found a reaction pathway - that does not prove it happened that way - I too thought the article title indicated spontaneous generation of RNA from primordial soup.
... and holy Unicode-less Slashdot, Batman. :-(
Beware: In C++, your friends can see your privates!
Demonstrating that another link in the evolutionary chain can happen without conscious intervention (spontaneously and mechanically) does not demonstrate the non-existence of an intelligent designer.
It, at best, removes a point that was previously used to defend ID.
But, logically, the inability to prove something does not constitute a disproof (that would be the fallacy of Argumentum ad Ignorantium).
Disclaimer: I am not an ID proponent. I am just a logician.
Soup...
So in other words: Even more chance of contamination.
Contamination.
'Nuff said.
Obviously. I'm sure they never accounted and corrected for that possibility. After all, it's not like these people are the type who would know anything about basic experimental science or anything.
a mixture that resembles what was likely the primordial soup.
Deja vu: I just had primordial soup for lunch.
Who would win this election: Andrew Weiner vs Andrew Weiner's weiner.
I've assembled a Windows XP kernel from Campbell's cream of leek soup.
From what I know plenty of previous attempts or rather "succesful" attemps have been shown to be due to contamination.
Now, I'm not saying these people don't know what they are doing, I'm saying the chance of contamination with discrete amounts of RNA / RNA bases / whatever in my eyes are probably far greater than the chance of actually making RNA.
(and no, I'm not some sort of creationist bastard heh)
In other news :
Witchdoctor creates soup from scientists who were studying primordials .
I thought the headline said that scientists create RIAA ...see, being from primordial soup...oh nevermind. No soup for you!
Todos mis movimientos están friamente calculados
Anyone that only scans the synopsis is going to get the wrong idea. Read the article...it's more than likely that this never occurred in nature. Since when do organisms add material and cleanse and add and cleanse? Who threw the sugar in the first primordial soup? Where would RNA get it's instructions? There are too many holes... this isn't a breakthrough in science, It's an episode of "The Frugal Gourmet"
This is the reaction sequence that's being proposed here: link.
Previously, the sticking point was that there was no logical way for the sugar (ribose) to spontaneously attach to the base. Organisms use enzymes to transfer a ribose phosphate group to a base, but of course, in the time before enzymes could be coded for, that wouldn't be possible. This sequence neatly sidesteps that, and also provides a more logical reason for phosphate to be involved; it is the reagent that attacks that tricyclic pyrimidosugar, breaking the bond to form ribocytidine phosphate.
Coincidentally, UV light deaminates cytosine to form uracil, which is where that second base comes from. This is why DNA uses thymine instead of uracil, by the way- as the archival storage medium for our genetic information, it would be unwise to have one base easily interconvert into another. The shorter expected lifetime of RNA means the interconversion is not a concern, though.
"FDA staff reviewers expressed concern about the number of patients who were left out of the study because they died."
What are your credentials, and why should we believe your arbitrary assertion? Could you give examples of past failures due to contamination? Could you tell us, given the particular set up of this experiment, what the possible vector of contamination is? Could you tell us why you think this particular experiment could not have created RNA? What are the difficulties that this set up does not address?
Or maybe you could just admit that 'contamination' is a total shot in the dark with no evidence to back it up.
- None can love freedom heartily, but good men; the rest love not freedom, but license. -- John Milton
Flying Spaghetti Monster unimpressed.
I earn a living (well, if you can call it that) doing biochemical research, but frankly I don't care if you believe me (RTFA, it pretty much speaks for itself).
Sorry, not bored enough to give examples, but using google scholar will most definitely help you (if you are that bored ;-).
Possible vector of contamination? Are you serious? Try just about everything they may have come into contact with.... removal of "all things resembling RNA" is much easier than it sounds... destruction of RNA strands, yes... quite easy (however that may introduce yet more contamination ;-). Removal of all nucleotides... good luck.
Contamination is actally quite a good shot as to what may have brought on at least the start of the process...
Did I mention I'm not that worried if you don't believe me? :-)
So in other words: Even more chance of contamination.
No. Even less chance of contamination, because until you reach the final step ANY contamination would cause an immediate failure of the process.
"Sutherland says [...] 'The key turned out to be the order that the ingredients are added and the way you put them together -- like making a soufflé.'"
How much clearer does it need to be made to you amoral materialists that cooking dinner needs *a Chef*?
The only thing I regret is that Sutherland compared God's Work to making a "soufflé". Couldn't he have used a good Christian American recipe?
Like omelette!
Rich And Stupid is not so bad as Working For Rich And Stupid.
Contamination. 'Nuff said.
Obviously. I'm sure they never accounted and corrected for that possibility. After all, it's not like these people are the type who would know anything about basic experimental science or anything.
Sometimes even the researchers think it's contamination, but the story's too good for journalists to pass up. A memorable example:
"Scientists at University of Alabama sequenced a 130-nucleotide long mitochondrial DNA sequence from dinosaur vertebrae, and found that it was 100% homologous to mitochondrial DNA from turkeys. However, the scientists themselves 'remain quite sceptical of our own work' and noted that they had been consuming turkey sandwiches in the laboratory."
Even though the triceratops-turkey 'finding' was never published and eventually dismissed by the researchers, the false result was leaked onto the internet, where it can still be found today.
This RNA synthesis paper, however, has no such caveats.
Looking at the flow chart I get the idea that these folks have done a good job of showing succinctly their novel idea. It doesn't look so terribly difficult or different. But nobody else seems to have come up with it in forty years. And even if it does not truly represent what happened it is a big step towards and inspiration for those who would propose a better idea. It also provides an opportunity to research many other of life's puzzles.
Well done!
Was it Campbell's or Progresso?
#DeleteChrome
Frank N. Furter: It was an ACCIDENT!
Fascism starts when the efficiency of the government becomes more important than the rights of the people.
I don't really see the point of this in the argument. We already know that there must be SOME way to form all the biochemicals, or they wouldn't exist to begin with, whether there's a Designer or not.
Then again, I don't waste my time arguing about ID to begin with...
Also: abiogenesis refers to life coming from nothing. This is RNA, not a living organism. It's one step closer, but it is not, in fact, a demonstration of abiogenesis.
can someone give a quick explanation on how RNA is different from DNA? why is it relevant?
d) God is actually a woman. Powerful, but insecure, and she needs you to show her how much you love her all the time. If you don't, she'll get depressed and eat her weight in mint-chocolate chip ice cream, in which case she'll end up omnipresent in more ways than one.
This is like saying "Scientists find a way of creating diamonds from carbon." Its easy to say you figured out how to do something when you get to guess what the materials really are in the first place. They don't really know what "primordial soup" would have been. They just said "hey, we can make RNA out of this random shit we figured would be laying around... using this expensive equipment and a method that requires accurate timing and purification and controls."
don't get me wrong, I'm willing to look at "random accident" as a method for the creation of life, but this article is bullshit. Now if you'll excuse me, I'm going to go write an article showing that a copper mine with sand in it can evolve into a circuit board for a car stereo with a few simple steps and a bunch of human intervention...
Will that prove abiogenesis or ID? ;-)
'Likes to play mind games' was option c)
- None can love freedom heartily, but good men; the rest love not freedom, but license. -- John Milton
Is God willing to prevent evil, but not able? Then He is not omnipotent. Is He able, but not willing? Then He is malevolent. Is He both able and willing? Then whence cometh evil? Is He neither able nor willing? Then why call Him God?
-Epicurus, 300 BCE
The refrain from fundamentalists, Christian and Muslim and Jew alike, is because he is God, and he said so, according to this really old book. Which is usually the inerrant word of God - they just can't agree on which version is the "perfect" word. Once you try to engage someone who firmly believes that they know what God thinks, there's no use in trying to apply logic.
One of my favorite David Cross bits is where he's asking out loud for the name of the television show where there's this guy on stage, and everyone in the television audience believes he can talk to the dead. The crowd in front of David keeps shouting out "Crossing Over!"
And then David says, "Oh no, it was church, it was church."
You just made three unsupported and ridiculous assertions as if they were a logical argument. Nice hat trick.
Religion does not need to rely on faith. Buddhism certainly doesn't, but I know some consider that a philosophy, not a religion. Still, it is listed as a major world religion, and it requires no one to take anything on faith.
Predestination and free will are both pointless human speculations unsupported by any human experiences, and if free will were real, it would be a curse, not a gift, especially considering your God's planned punishments for going against arbitrary rules that you have no way of knowing came from Him.
If God were to be in residence and free will were real, God's presence would not diminish free will. So what? At most, nobody would choose to sin anymore. I don't choose to froom, either, and my not being able to choose to froom does not diminish any free will I may have.
But people could still choose to sin knowing God existed, I know I would, just to register my disapproval of God's arbitrary and unjust actions. Infinite punishment for finite transgressions, my ass. Fuck you, God, I'm going out to fuck a guy JUST TO PISS YOU OFF, YOU SHIT! I'm not even gay, I'll probably hate it, but I'm going to do it just because you said you'd torture me forever if I did. I don't negotiate with terrorists.
- None can love freedom heartily, but good men; the rest love not freedom, but license. -- John Milton
That when it's a team of AMERICAN scientists doing anything the heading says "American Scientists...", but when it's any other country it's just "Scientists..."?
Looks like an intelligently designed process to me.
So let's assume this pathway occurred in the primordial soup.
How long would ancient conditions let it stick around to advance to more steps?
Except for ending slavery, the Nazis, communism, & securing American independence, war has never solved anything.
Reading what you wrote is like reading something written by the crack-addled, bastard love child of R. Buckminster Fuller and Emily Dickinson.
The sides aren't what you think they are. There are more than two sides. Most people are on more than one side. I'm not on a side at all. Seriously, lay off the drugs or I will be forced to blow your mind some more, man.
- None can love freedom heartily, but good men; the rest love not freedom, but license. -- John Milton
Life is complex and it works well. It's not proof, it's evidence. The laws of physics yield a consistent universe. It's not proof, it's evidence.
Both of these things are only evidence of themselves. Nothing more. You cannot logically extrapolate these things into anything more than they are without direct evidence of something more. No matter how much evidence the universe gives of its own existence, it does not point to anything beyond that, be it God or invisible unicorns or Flying Spaghetti Monsters, sauce be upon him, or anything else. The current body of evidence points only to its own existence.
If you want to posit the existence of God, based on the evidence provided by the universe, then you need direct evidence of God (well, you also need a clear, falsifiable definition of God). Otherwise, Occam's Razor gives us the more likely conclusion. Given the same body of evidence, the simpler explanation tends to be the correct explanation, unless more evidence appears to show otherwise.
In this case, the body of evidence: The universe.
- H0.) The universe just exists.
- H1.) The universe exists because God created it. God just exists.
Given the same body of evidence, H0 is the more likely explanation, and there is no REASON to assume H1 without further evidence.
While you cannot prove a negative, in science, lack of evidence for H1 is provisional evidence for H0. Also, any scientist knows that you can NEVER prove anything based on observation. You can only disprove it OR decrease the likelihood of its falseness.
NB: Most of the "you" in this post is the general "you" not a specific "you" to the parent post.
"Empathise with stupidity, and you're halfway to thinking like an idiot." - Iain M. Banks
Well, lets say you have a few billion gallons of "soup" and you let it stew for a few hundred million years...
With enough trials low probability events become near certainties.
Warning: this article may contain humor, sarcasm, parody, and perhaps even irony. Read at your own risk.
Poof!!!
- Anonymous God
And then... when those organisms evolute a bit... they will conclude by their arrogance that they were made by... coincidence.
I believe it. Cells make proteins from RNA, so it makes sense that that mechanism evolved first. Then, DNA later evolved as storage, to keep the useful genes and let them replicate.
Indeed; nothing can.
Nor indeed is there any requirement or reason to "demonstrate the non-existence of X," where there is no evidence for the putative existence of X.
On a side not, this discovery doesn't demonstrate the non-existence of the tooth fairy either.
Better to be despised for too anxious apprehensions, than ruined by too confident a security. --Edmund Burke
While you cannot prove a negative
Even if you squash every one you see they keep coming back!
http://www.google.com/#hl=en&q=can't+prove+a+negative
Maybe I'll put some links in my sig...that'd be like strapping always-spraying cans of Raid to my belt.
"When information is power, privacy is freedom" - Jah-Wren Ryel
No primordial soup for you!
Far be it from me to minimize such a significant accomplishment, but, as the article points out, two base RNA molecules have been created so far. So, there are still two more that need to be created in order to make the 'lucky' four.
I imagine it will only take a bit of time to figure out the last two now that the recipe to create things in the first place is known. Nevertheless, there is still a bit more to the puzzle at this point. In any event, this team deserves a Nobel Prize.
And all our yesterdays have lighted fools The way to dusty death. --Will
Eh.
The more time that goes on the less likely RNA is able to stay intact for the next phase of the RNA world.
And the fossil record looks like the Earth cools and almost immediately (geologically speaking) you get bacteria around 3.85 billion years ago.
Except for ending slavery, the Nazis, communism, & securing American independence, war has never solved anything.
We have just proven that God exists, and She's a Woman. As evidence, I present The World Around You. Look at it. Think about it. C'mon.
Dinosaur bones. Buried in the ground. Makes it look like She isn't there. So we say, 'Okay, I get it. You aren't there,' and She gets all pouty and says, "What about all that majestic crap that some dude told you I did but you never saw me do? THEY WROTE BOOKS ABOUT IT!"
YOU don't have any books written about you, I'd know it if you did, I'M OMNISCIENT! Your greatest achievement is a fricken +5 on some blog no one important even reads."
What about that, huh, Mr. About-to-get-his-ass-thrown-in-a-lake-of-fire? Did you stop to consider ANY of that shit when you saw those dinosaur bones WELL DID YOU?"
Why won't you talk to me? Don't you know I love you? C'mere, let's snuggle forever. Just say you were sorry. Just admit you were wrong, and we'll snuggle wuggle forever and I'll make you so happy! My love is the best thing you've ever had."
WHY WON'T YOU ANSWER ME? IT'S LIKE YOU AREN'T EVEN LISTENING! FUCK YOU! I DON'T LOVE YOU AND I NEVER DID! DIE IN A FIRE!"
A Woman. No doubt in my mind now. My humblest apologies if any of this offends you, my Lady.
i only meant it as a joke...
Actually, they've recently synthesized DNA from another fossil of another dinosaur, which, upon comparison, supports the T-Rex DNA. It's in one of the semi-recent Nature podcasts.
Your point is good, but some days the universe kicks you in the head especially hard when it comes time to choose an example.
Looks like they finally have the blueprints to build Bender.
I don't negotiate with terrorists.
It's your religion. He's your god. You go to hell.
There's another theory, one that says life came from other planets - it's called panspermia
(Yes, yes, I know... don't bother trying to make a joke out of it, it always turns out clumsy)
To quote Sir Frederick Hoyle: "There are those who believe... that life here began out there!"
"Slow down, Cowboy! It has been 3 years, 7 months and 26 days since you last successfully posted a comment."
I always thought of it as weird, the whole ID - Evolution debate , I mean think of it, on evolution side you have people that use intelligence ,science and logic to search for answers and create models that describe the natural world. ID proponents believe in God and that God created all (ie. Some sort of intelligence was needed to create something, exactly what these guys just "proved".)
So as much as evolutionist is trying to use science to "prove" evolution , the more they have to believe that what they are saying happened.
Evolutionist = believe in random actions != science.
ID != believe in random actions == science
Scientist finds bug in soup
from the that's-no-tasty-soup-for-you dept.
"The RNH (Random gNat Hypothesis) proposed 40 years ago
suggested that somewhere, some scientist is definitely finding a
bug in his/her soup. Now a team of scientists bolsters this
hypothesis, having assembled soups in the lab from a mixture
that resembles what gnats like to eat in the wild. 'Until now,'
Science News reports, 'scientists couldn't figure
out the necessary ingredients that created the probabilities
necessary to support RNH.' The new work started the RNH
soup development from a different angle than what earlier
luncheons, err, work had tried."
--TheOrangeSquid Is it any wonder things seem so awry? We swim in a sea of confusion and don't have to think to survive
Cough syrup! Nothing but plain, ordinary, over-the-counter children's cough syrup!
"Those who do not want to imitate anything, produce nothing." -- Salvador Dali
Thought that the damn scientists had created another RIAA. They never think of the consequences!
Almost immediately, only 200 million years.
You forgot a third quality without which God is not God: He should also be infinitely good, he does not like us to suffer.
That goes against (a) and (c) in your argument, leaving only (b) he does not exist, at least not with those three qualities.
Raymond Chandler had one of his characters in his 1958 novel "Playback" say: "If God were omnipotent and omniscient in any literal sense, he wouldn't have bothered to make the Universe at all."
I think the simple fact that we exist shows that God, if he does exist, is not omniscient and omnipotent. Why create the Universe if you already know exactly how everything will happen?
Or, like another scientist did recently, you can just take all of the component bits and pieces, freeze it in ice, and leave it for 15 years.
At the end of it, you will have RNA and a bunch of amino acids.
This is why I read New Scientist magazine religiously.
Coming soon - pyrogyra
http://en.wikipedia.org/wiki/Devil's_Due_(TNG_episode)
"Devil's Due" is an episode of the science fiction television series Star Trek: The Next Generation. In this episode, the people of Ventax II believed in a devil-woman named Ardra (played by Marta DuBois). A thousand years before the episode, Ardra promised to solve all the world's problems. In return, the planet would become hers in a thousand years.
*************
The USS Enterprise receives a distress call from a Federation delegation on Ventax II, where the population is in a state of panic because they are convinced that their world will soon end. A thousand years ago, according to Ventaxian history, the population entered a Faustian deal with Ardra, their mythology's devil, in exchange for helping to clean and improve their heavily polluted planet. As the millennium is about to come to a close, the planet has recently begun experiencing earthquakes that were said to precede Ardra's arrival, fueling the fears of the Ventaxian people. As Captian Picard and Data discuss the matter with the Ventaxian leader, a sultry brunette appears in the chamber, announcing herself as Ardra. She proves her identity by seemingly starting an earthquake at will, and changing her form into that of both the Christian and then the Klingon devil. Ardra states that the thousand years are over and that she has come to claim the planet, including anything in orbit--that is, including the Enterprise. When Picard and Data attempt to return to the Enterprise to contemplate this development, the Enterprise disappears before their eyes.
Picard, believing Ardra to be a fraud, calls for a Ventaxian arbitration hearing, which Ardra agrees to as long as Data acts as the arbitor, due to his ability to be completely impartial despite his Starfleet position. Picard agrees to the choice of Data, knowing that he also cannot feel pressed by Ardra. The hearing reveals that Ardra never assisted the planet in cleaning up their pollution; the people improved their planet gradually after the deal was made. Despite his claims, Picard cannot convince the Ventaxian leader that Ardra is playing a con game. As the hearing continues, La Forge analyzes Ardra's power and discovers two cloaked ships in orbit: the Enterprise and another ship. La Forge relays this information to Picard, who, after a short recess, performs the some of Ardra's "tricks" for the Ventaxian leader and for Data. Picard reveals that a team from the Enterprise was able to seize Ardra's cloaked ship, and used the technology aboard it to create the same effects. Picard further explains that "Ardra" and her conspirators were simply trying to take advantage of the Ventaxian mythology. With the hearing closed, "Ardra" attempts to simply abrogate the contract but finds herself detained for her fraud by the Ventaxian government.
With the first link, the chain is forged.
Comment removed based on user account deletion
CREATION == DISCOVERY ?
Back in the day, we didn't have all these fancy RNA and DNA strands. If we wanted some damn primordial soup for dinner, we made it ourselves...from scratch!
DNA! HA! I *wish* we had DNA. We had to make our own proteins from just G! And for RNA we only had U! I still remember when Chuck Norris and I made our first cat. Hooey! What a mess! It was just GGG GGG GGG GGG strung together, but Chuck, he got it to work somehow...I wonder what ever happened to that cat?
Oh boy! Time to get my diaper changed!
Bunch of people make a RNA making soup in experiment and they claim that it proves "evolutionary chain can happen without conscious intervention"
hahaha
Funy!!! Slashdot is great place to observe young minds... and how they fit in the wall as bricks.
* "this" being what we can see/measure and determine with repeatable experiments about the universe.
I have determined that my sig is indeterminate.