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Scientists Demonstrate Mammalian Tissue Regeneration

telomerewhythere writes "A quest that began over a decade ago with a chance observation has reached a milestone: the identification of a gene that may regulate regeneration in mammals. The absence of this single gene, called p21, confers a healing potential in mice long thought to have been lost through evolution and reserved for creatures like flatworms, sponges, and some species of salamander. 'Unlike typical mammals, which heal wounds by forming a scar, these mice begin by forming a blastema, a structure associated with rapid cell growth and de-differentiation as seen in amphibians. According to the Wistar researchers, the loss of p21 causes the cells of these mice to behave more like embryonic stem cells than adult mammalian cells, and their findings provide solid evidence to link tissue regeneration to the control of cell division. "Much like a newt that has lost a limb, these mice will replace missing or damaged tissue with healthy tissue that lacks any sign of scarring," said the project's lead scientist.' Here is the academic paper for those with PNAS access."

23 of 260 comments (clear)

  1. So by jimbobborg · · Score: 4, Funny

    We can all be Wolverine now? Cool!

    1. Re:So by Monkeedude1212 · · Score: 5, Funny

      Minus the Claws. And the Adamantite interior. And the Rugged good looks - in your case, anyways.

    2. Re:So by K.+S.+Kyosuke · · Score: 4, Funny

      And be wary that this rather serious matter may take a tumorous twist.

      --
      Ezekiel 23:20
    3. Re:So by Jurily · · Score: 2, Funny

      And the Adamantite interior.

      You missed an expansion pack. He upgraded to Saronite when he reached 80.

    4. Re:So by Syberz · · Score: 2, Funny

      I have a feeling you should know something about the subject before weighing in.

      You sir are hanging out on the wrong internets.

      --
      ~Syberz
    5. Re:So by natehoy · · Score: 3, Funny

      I heard you were looking for some, so I went back in time and destroyed them all on this planet.

      Lovingly yours,
        - The Master

      --
      "This post contains words, known to the State of California to cause thought. Wash brain thoroughly after reading."
    6. Re:So by Luyseyal · · Score: 2, Funny

      There's an analogy with software development in there somewhere, if I could just flesh it out.

      Oh, I've got it. Managers will choose the quick patch over the proper fix every time due to competitive pressure.

      Where are my free internets?
      -l

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    7. Re:So by Anonymous Coward · · Score: 1, Funny

      Not only that, but consider the anti-aging possibilities:

      1. Get old
      2. Sequentially, & repeat:
            a. Amputate old body segments
            b. Scream like a motherfucker
            c. Regenerate yer parts with that "factory fresh" smell
      3. ???
      4. Profit!

      Don't worry about your brain, you can do one hemisphere at a time. And remember, corporate ownership of popular culture means all your important memories are already stored in the cloud!

    8. Re:So by Stephen+Tennant · · Score: 2, Funny

      I'm sure many a Slashdot reader will receive an upgrade in the looks department when they are able to heal acne scars. Now excuse me while I prepare for troll modding from butthurt pizzaface.

      --
      I spend most of my time in bed, darling.
  2. Now I can finally start my restaurant... by Culture20 · · Score: 5, Funny

    Now I can finally start my restaurant (which specializes in mouse-tail delicacies) without PETA breathing down my neck. "Look: it's growing back!" Mouse-tail soup anyone?

    1. Re:Now I can finally start my restaurant... by Bakkster · · Score: 2, Funny

      "Waiter, there's a blastema in my soup."

      --
      Write your representatives! Repeal the 2nd Law of Thermodynamics!
    2. Re:Now I can finally start my restaurant... by Hatta · · Score: 5, Funny

      I think instead that it was cats who domesticated humans.

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      Give me Classic Slashdot or give me death!
    3. Re:Now I can finally start my restaurant... by HornWumpus · · Score: 4, Funny

      The cat the lives in my house has owners.

      My dogs.

      I feed the 'orange devil' though.

      The girl Lab thinks the little fucker is her baby. So does the cat. Lets her lick him clean like a new mama dog.

      The cat and the German shepherd play a game with the other neighborhood cats. The cat picks a fight then 'runs like a Frenchman' back to my yard where the dog pounces on the neighbor cat. Repeat.

      Might be a problem if he didn't knows cats are way more fun to chase then they are to catch.

      --
      John McAfee 'It was like that time I hired that Bangkok prostitute; to do my taxes, while I fucked my accountant'
  3. Degeneration by tedgyz · · Score: 2, Funny

    You know this discussion will degenerate into how this can be applied to growing a longer penis.

    --
    "No matter where you go, there you are." -- Buckaroo Banzai
    1. Re:Degeneration by protodevilin · · Score: 3, Funny

      Then I hope it doesn't involve having to amputate the penis first.

    2. Re:Degeneration by Anonymous Coward · · Score: 2, Funny

      I don't see why it should. Just have the doctor cause a new one to grow there next to the one you already have. Then, when the new one is in place, have tubing moved over, and the old one removed. Or just keep both, whatever strikes your fancy.

      Damn I can't believe I just spent that much time thinking that through... I'm glad I thought to post as AC.

  4. Re:It will be interesting to see... by AioKits · · Score: 4, Funny

    Remember, you are not a newt.

    I got better...

    --
    "Quote me as saying I was mis-quoted." -Groucho Marx
  5. Re:Be careful when fooling Mother Nature by lawpoop · · Score: 4, Funny

    Darwinism is cruel... Nature does things for a reason.

    Narture wants to be anthropomorphized ;)

    It nature is so cruel and barbaric, then for what reason did it evolve human beings who feel sympathy, empathy, are able to learn, and practice healing arts?

    --
    Computers are useless. They can only give you answers.
    -- Pablo Picasso
  6. PETA....... by axor1337 · · Score: 1, Funny

    People Eating Tasty Animals But then as the Nugent says "You have to Kill it, before you Grill it."

    --
    there are 10 types of people in this world, those who read binary and those who don't. which are you!
    1. Re:PETA....... by natehoy · · Score: 2, Funny

      Just remember, there's room for all of God's creatures... right there, next to the mashed potatoes.

      --
      "This post contains words, known to the State of California to cause thought. Wash brain thoroughly after reading."
  7. I have access to a PNAS... by zero_out · · Score: 4, Funny

    Here is the academic paper for those with PNAS access.

    I have access to a PNAS. Sometimes I let my wife have access to it, too.

  8. Re:caveat by rockNme2349 · · Score: 3, Funny

    there are logistical, economic and public relations issues with trying to keep hundreds of chimpanzees in order to punch holes in their ears.

    Ahh, high school...

    --
    Sewage Treatment Facilities - "Our duty is clear."
  9. Re:caveat by ArbitraryDescriptor · · Score: 2, Funny

    You could probably keep 10+ mice, quite comfortably, in the volume of space an adult pig takes up. I could probably keep 100 caged mice in my office, with ample room for them to run around and live relatively normal mouse-lives; whereas a single pig would probably be tearing this place up and demanding half* its body weight in food everyday. It would be ridiculous.

    No, the logical solution here is to find out which gene we need to turn off to make mice taste like pork and just go from there.

    This post paid for by Monsanto and a grant from the Moreau Foundation.
    Macon: It ain't just a city in Georgia

    *IANAPF