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Japanese Guts Are Made For Sushi

cremeglace writes "Americans don't have the guts for sushi. At least that's the implication of a new study, which finds that Japanese people harbor enzymes in their intestinal bacteria that help them digest seaweed, enzymes that North Americans lack. What's more, Japanese may have first acquired these enzymes by eating bacteria that thrive on seaweed in the open ocean."

51 of 309 comments (clear)

  1. Stomach cancer by Anonymous Coward · · Score: 2, Interesting

    I wonder if that bacteria is (part of) the reason stomach cancer is a major killer in Japan. Lost a friend to it.

    1. Re:Stomach cancer by gomiam · · Score: 2, Interesting

      Bacteria (helicobacter pylorii, more specifically) are related to a lot of ulcer-induced stomach cancer. As the bacteria they talk about live in the intestines (that's what gut means) I don't think they have much to do with it. I may be mistaken, though.

    2. Re:Stomach cancer by Profane+MuthaFucka · · Score: 4, Funny

      I wonder if that bacteria is the reason for the blurry qualities of genitals in Japan.

      --
      Fascism trolls keeping me up every night. When I starts a preachin', he HITS ME WITH HIS REICH!
  2. Implications by Anonymous Coward · · Score: 2, Interesting

    This doesn't seem evolutionary so much as it appears that they grew up eating the bacteria. If I'm wrong, would somebody please tell me where my thought process is hitting a disconnect?

    1. Re:Implications by bkr1_2k · · Score: 2, Interesting

      Newborns don't have the enzymes (supposedly) to break down meat either, but we in the western world seem to do fine with that. I suspect this is more like you're thinking, a habitual thing that your body adapts to based on your other dietary intakes.

      --
      "Growing old is inevitable; growing up is optional."
    2. Re:Implications by RebelWithoutAClue · · Score: 2, Informative

      It's probably not that hard. You could probably get a faecal transplant if you really wanted to.

      --
      "However beautiful the strategy, you should occasionally look at the results" - Winston Churchill
  3. Am i missing something? by Daetrin · · Score: 5, Interesting

    I thought that everyone started out with pretty much zero gut bacteria and acquire them based on what they eat. (And sometimes people lose all their gut bacteria from various medical treatments and have to work to restore them.)

    So the japanese end up with the bacteria/enzymes do digest sushi because... they eat a lot of sushi. Presumably anyone else could develop a colony of such bacteria/enzymes by also eating a lot of sushi?

    That would mean the division isn't whether you're Japanese or American or something else. It's just whether or not you eat a lot of sushi.

    --
    This Space Intentionally Left Blank
    1. Re:Am i missing something? by polar+red · · Score: 2, Interesting

      I tought we got some of our mothers' bacterial community during pregnancy. is there a biologist or doctor in the room ?

      --
      Yes, I'm left. You have a problem with that?
    2. Re:Am i missing something? by Misanthrope · · Score: 4, Interesting

      Some of your gut microflora and fauna comes from your mom during the birthing process, others from breastfeeding and some from what you eat on a regular basis. This is interesting because the genes are transferred supposedly from the bugs living on seaweed to the bugs living in your gut, letting the same species of gut bugs to develop an ability to digest seaweed better.

    3. Re:Am i missing something? by Cylix · · Score: 4, Funny

      I'm not a biologist nor in any sense of the word am I qualified to answer your question. However, I feel that I might be able to lend some perspective on that matter that might otherwise be useful in gaining a firmer level of comprehension on the issue at hand.

      Onto the question regarding the transfer of some of the bacteria from mother to child I'm almost certain that someone may be able to shed some light on this puzzle.

      As noted earlier, I'm almost nearly certain that I am in no way shape or form the person who could assist in this conundrum.

      Don't hesitate to ask should you require further assistance.

      --
      "You should always go to other people's funerals; otherwise, they won't come to yours." -- Yogi Berra
    4. Re:Am i missing something? by leenks · · Score: 2, Insightful

      Isn't that basically what all scientific papers are though? Scientific method applied to hunches or experiences to confirm a behaviour?

  4. North Americans? by Froeschle · · Score: 3, Interesting

    What about North Americans of Japanese decent?

  5. No enzymes, eh? by ibsteve2u · · Score: 4, Funny

    Well, I'll be; and here I thought my brief illness on an Okinawan beach resulted from my consuming budweiser and salty dogs all night and then passing out on the beach - and failing to wake up when the sun came up.

    It wasn't alcohol, heat stroke, or the incandescent sunburn - it was the seaweed from that piece of sushi I had the day before!

    --
    Orwell: "In a Time of Universal Deceit, telling the Truth is a Revolutionary Act"
  6. I must have the enzyme for french fries. by ipquickly · · Score: 3, Insightful

    Is it not obvious that if you regularly eat a certain type of food, you will eventually have bacteria that thrive in your gut because of the regularity of what you eat?

    What would really surprise me is if they find that an American living in Japan and eating a 'local' diet would not acquire these bacteria.

    I'm sure by now I've acquired bacteria that help with the digestion of french fries and poutine.

    1. Re:I must have the enzyme for french fries. by Cyberllama · · Score: 2, Insightful

      Not all of Europe, actually, just all of northern Europe and also East Africa and places were the populations are descended primarily of those stocks. Wikipedia has a map!

      http://en.wikipedia.org/wiki/File:LacIntol-World2.png

  7. population sample by networkzombie · · Score: 5, Insightful

    Czjzek's team compared the microbial genomes of 13 Japanese people with those of 18 North Americans.
    If I used this many test subjects in my job I would get fired.

    1. Re:population sample by Thanshin · · Score: 4, Funny

      Czjzek's team compared the microbial genomes of 13 Japanese people with those of 18 North Americans.

      If I used this many test subjects in my job I would get fired.

      They don't even let me use test subjects in my job. Even after assuring them that most won't die.

    2. Re:population sample by zippthorne · · Score: 2, Insightful

      31 people, but billions of gut bacteria...

      --
      Can you be Even More Awesome?!
  8. ...and Americans are made for steak... by ook_boo · · Score: 3, Insightful

    Yeah, 20 years ago there was similar pseudo-science published in Japan claiming that Americans were specially built to eat hamburgers.

  9. Ammo for Racism by eheien · · Score: 5, Interesting

    Just what we need, more "Japanese are unique" idiocy to justify racism and discrimination in Japan. So far we've heard that "Japanese intestines are longer, so Japanese can't eat foreign beef", "Japanese brains are unique, so only Japanese people can speak the Japanese language." and so on, all of which are supported by pseudo-scientific studies such as this one.

    This sort of incomplete research just feeds the view of racial uniqueness (and superiority) among Japanese and justifies their racism and discrimination against others.

    1. Re:Ammo for Racism by outsider007 · · Score: 5, Funny

      This sort of incomplete research just feeds the view of racial uniqueness (and superiority) among Japanese and justifies their racism and discrimination against others.

      They can keep their ability to digest seaweed.
      I'll just try to get by on my > 4" weiner.

      --
      If you mod me down the terrorists will have won
    2. Re:Ammo for Racism by HungWeiLo · · Score: 2, Interesting

      My hunch is that this is an economic strategy. Japan has a history of doing stuff like this before - this is not strictly an example about genetic superiority - but they have claimed that Japanese snow has a unique texture, and therefore only Japanese-manufactured skis are suitable for their ski resorts.

      A lot of seaweed gets exported from China and Korea. This may be to stem the import of foreign seaweed.

      --
      There are a huge number of yeast infections in this county. Probably because we're downriver from the bread factory.
  10. Idle? by Escaflowne · · Score: 2, Informative

    What a surprise, samzenpus posting an idle article on the main page under a heading such as Science or Your Rights Online so his articles get more views.

    Seriously, take a look at the articles you've posted today samzenpus and the sections you placed them in. All, but one of your stories are Idle and yet all of them appear on the main page.

    Thanks for bypassing my filters and cluttering up people's pages with your nonsense.

  11. BREAKING NEWS... by linzeal · · Score: 4, Funny

    Killer Whale guts are made for Japanese, story at 11.

  12. babies by thoughtsatthemoment · · Score: 4, Insightful

    The study maybe valid if they can find the enzymes in Japanese babies. Otherwise it can be said that the Japanese have the enzymes because they eat lots of sushi.

    1. Re:babies by Opyros · · Score: 2, Informative
      One of them was a baby, according to this article:

      For now, it's not clear how long these marine genes have been living inside the bowels of the Japanese. People might only gain the genes after eating lots and lots of sushi but Hehemann has some evidence that they could be passed down from parent to child. One of the people he studied was an unweaned baby girl, who had clearly never eaten a mouthful of sushi in her life. And yet, her gut bacteria had a porphyranase gene, just as her mother's did. We already known that mums can pass on their microbiomes to their children, so if mummy's gut bacteria can break down seaweed carbs, then baby's bugs should also be able to.

  13. Ah! by Superdarion · · Score: 2, Insightful

    So that's why nobody eats sushi outside of Japan!

  14. strange diet by CaptainNerdCave · · Score: 5, Funny

    I'll just try to get by on my > 4" weiner.

    That seems like an odd diet, I hope it serves you well.

    1. Re:strange diet by outsider007 · · Score: 4, Funny

      Your mother swears by it.

      --
      If you mod me down the terrorists will have won
    2. Re:strange diet by Maxo-Texas · · Score: 2, Funny

      How is she able to swear with her mouth full?

      --
      She was like chocolate when she drank... semi-sweet at first and then increasingly bitter.
  15. Bowel obstruction by AlpineR · · Score: 5, Interesting

    Speaking of cold, dead digestive tracts: A few years ago, I got terribly ill while on vacation. Loss of appetite, waves of tremendous abdominal cramps, and vomiting. My intestines had plugged up and it took some intervention to get them moving again.

    I put some of the blame on a sushi lunch I ate that day. I'd eaten sushi often before, but this restaurant used a lot more seaweed in the dishes than I was accustomed to. Even as I was eating, I had second thoughts about whether what I was putting into my mouth was actually edible. But I figured it seemed strange to me only because that Japanese restaurant was more authentic than the Americanized sushi places where I usually dined.

    Now I wonder whether that seaweed would be edible to Japanese guts, but truly was inedible to mine.

    1. Re:Bowel obstruction by voodoo+cheesecake · · Score: 5, Funny

      Some with weaker constitutions would flinch, but I'd give you a mod point if I had any at the moment. As an Alaska'n fisherman, let me tell you that North Pacific bull kelp will rip you up pretty good, but I mix mine with jelly fish for that extra zing! Prepare your bull kelp and brown snot looking jelly fish with vinegar and high voltage, about 30kV or so should do the trick - just enough to evaporate it within a minute. Any longer than that and it starts to get a funny after taste.. Once it has cooled, sprinkle it on smoked tuna or sockeye salmon. Wash it down with orange Jolt and Bacardi 151 - of course, you should only do this on shore at the local tavern. Feel free to experiment with other beverages suitable to your taste if you want to whimp out.

    2. Re:Bowel obstruction by jim_v2000 · · Score: 2, Interesting

      I doubt it. It's not genetic...as in it has nothing to do with someone being Japanese. It boils down to people who eat more sushi have more of the related bacteria.

      --
      Don't take life so seriously. No one makes it out alive.
  16. Many asians can't digest milk by Viol8 · · Score: 2, Interesting

    A large proportion suffer lactose intolerance which means milk and yoghurts are out though I believe they can still eat some cheeses where the lactose has been converted into something else. If anyone has ever wondered why you never see dairy food in chinese or japanese restaurants - theres your answer.

    Anyway , most veg if cooked long enough can be digested by the human gut so these enzymes only give them an advantage if they eat it partially cooked or raw.

  17. Japanese yogurt cultures by mattr · · Score: 3, Interesting

    TFA is not clear whether non-Japanese really cannot break down seaweed at all.
    In Japan it is popular to buy yogurt with live culture, for example there is Meiji's LB51 (lacto bacillus 51) yogurt supposedly good for your gut.
    Might be cool if a yogurt with this organism is made.
    Of course if you could just eat non-sterile seaweed maybe it would make a culture for you in your gut.. anybody know about edible seaweeds that would have this?
    I've had seaweed salad and maybe that would have it.
    Also the American gut is supposedly longer does that balance not having the enzyme at all?

  18. Nothing new really by Nephrite · · Score: 2, Interesting

    Let's recall that tribes that life off hunting have more lactose intolerant people that those that practice livestock breeding, that certain northern tribes of Chukchas and Eskimo doesn't have ensimes to get rid of alcohol so they become alcoholics easily and so on and so on.

  19. really? by malkien · · Score: 2, Insightful

    organisms adapt to local diet.
    film at 11.

  20. But then it makes no sense by Moraelin · · Score: 4, Insightful

    But then it makes no sense to say they acquired it from bacteria.

    Genes don't transfer from bacteria to mammals. Genes transfer between bacteria, via exchange of plasmids. (Which is one reason why antibiotic resistance spreads so fast.) But your cells don't have the mechansims to acquire such a plasmid, and wouldn't know what to do with it. You don't even have the regulating proteins or the ribosome to deal with a _circular_ DNA strand, and one outside the nucleus at that.

    At this point someone will probably have the knee-jerk reaction to explain how viruses can account for horizontal gene transfer, 'cause they read that notion at some point and it sounded so smart. Not so fast. Viruses are quite specialized in what they attach to. They depend on very specific nucleotid sequences, which is why you can have a virus that attacks your upper respiratory tract, but can't affect your lungs, or viceversa. Viruses that prey on bacteria, the so called "phages", have very specialized capsids and mechanisms to inject themselves into a bacterium, and are even more specialized in what they can attach to. Which is why for example you can spray meat with a phage which destroys Lysteria, but won't destroy your intestinal flora. A virus that's suited to infect both a bacterium _and_ your gut lining and transfer genes from one to the other, is almost an impossibility, and at any rate to the best of my knowledge none was ever identified.

    --
    A polar bear is a cartesian bear after a coordinate transform.
    1. Re:But then it makes no sense by Sleepy · · Score: 2, Interesting

      >Genes don't transfer from bacteria to mammals.

      I would not cling to that view too strongly - there's some circumstantial evidence that genes can be transfered between unrelated species. Don't ask me to explain it - it's not understood as yet. But as an example you could Google, some GMO genes are being found in plant and insect species and it looks like the result of an unknown transfer process. It may be that mutations are not entirely random, but can be based on exposure (such as diet).

    2. Re:But then it makes no sense by jc42 · · Score: 2, Insightful

      But then it makes no sense to say they acquired it from bacteria. Genes don't transfer from bacteria to mammals. Genes transfer between bacteria, via exchange of plasmids.

      It's more accurate to say that we don't know of gene transfer between bacteria and mammals (or eukaryotes in general). It may happen, but it's probably not common.

      But what the article is about is gene transfer between bacteria in the gut. This is something that's well understood in medical circles, but not in the general population. Our digestive system depends on a lot of bacteria to provide many of our digestive enzymes. We do produce digestive enzymes ourselves, but not nearly enough, and we'd get a lot less value from our food without the assistance of all those bacteria.

      The suggestion is that the enzymes to digest seaweeds came from bacteria that were ingested along with the seaweeds, and in Japan, those bacteria exchanged some genes with the more common human digestive bacteria, so that the bacteria that are adapted to our gut picked up the seaweed-digesting enzymes. From what is known about bacterial genetics, this isn't a radical suggestion. It's what you'd expect to happen when a human population adopts some new food stuff that's difficult to digest.

      It is possible that the genes that make some of those seaweed-digesting enzymes have also transferred into the human genome in Japan. But it's a lot less likely. That's the sort of job that our digestive system prefers to farm out to subcontracting bacteria.

      --
      Those who do study history are doomed to stand helplessly by while everyone else repeats it.
  21. North Americans? What, like the Sioux? by evilandi · · Score: 2, Interesting

    I didn't realise that the appetite for sushi amongst the Sioux, Cherokee and other North Americans was quite such a concern.

    Or did they mean Europeans?

    If you're going to discuss genetic differences, you do need to be accurate.

    --
    Andrew Oakley - www.aoakley.com
    1. Re:North Americans? What, like the Sioux? by evilandi · · Score: 2, Informative

      'Caucasian' includes the peoples of the Indian and Arabian subcontinents, as well as the European subcontinent.

      "I do not think it means what you think it means."

      --
      Andrew Oakley - www.aoakley.com
  22. Sigh...some of you are dumb by magamiako1 · · Score: 4, Informative

    The article states clearly that:

    Gene transfer from the living bacteria transferred into the Japanese people's genome that produces enzymes in the gut that make breaking down seaweed easier (i.e. they get more from it).

    They didn't say you couldn't eat seaweed and that it was bad for you if you don't have these enzymes, just that it's better for you if you do.

  23. To tune your guts... by AlecC · · Score: 2, Interesting

    So Japanese people have a seaweed digesting bacterium in their guts. So sushi restaurants could offer visiting westerners a small culture of this bacterium, and they would be set up to digest the seaweed. Before you go "Ewww, bacteria!", this is just what is being offered commercially as "pro-biotic yogurt". You would probably need a top-up on every visit to Japan, because the bacterium would probably die out without a regular supply of seaweed.

    --
    Consciousness is an illusion caused by an excess of self consciousness.
  24. Re:Americans by TheRaven64 · · Score: 2, Informative

    Not having the enzymes won't make any difference to your enjoyment of the dish, it will just mean that the seaweed won't be broken down for digestion. It will simply pass through your system like fibre. You can enjoy it, you just won't get any nutrition from it. I'm not really surprised by this discovery; it explains why I feel hungry about an hour after eating sushi.

    --
    I am TheRaven on Soylent News
  25. Re:in natural childbirth by Anonymous Coward · · Score: 2, Informative

    Not if they're giving birth with a competent doctor/midwife/whoever. A catheter and proper procedure keeps all that off the baby. I have two kids, so I've seen it happen. Next time try going to a hospital instead of a biker bar.

  26. Sample size by crossmr · · Score: 2, Insightful

    Czjzek's team compared the microbial genomes of 13 Japanese people with those of 18 North Americans. Five of the Japanese subjects harbored the enzyme, but among the North Americans, "we didn't find a single one," says Czjzek, whose team reports its findings tomorrow in Nature.

    such a big sample size, how could they possibly be wrong..

  27. you're missing the implication by circletimessquare · · Score: 3, Interesting

    if you artificially make the birthing process clean, you are not adequately inoculating your baby's digestive tract with the mother's gut flora

    perhaps setting the kid up for opportunistic infection in the first days of life, inadequate digestion, malformed immune system (allergies), etc.

    so you reacted to the ugliness of getting shat upon by your mother at birth, but your delicate sensibilities are not the issue: for millions of years, getting shit on at birth has meant we evolved with the timing of the introduction of the full spectrum of the mother's gut bacteria at time of birth. meaning a delay in that timing could be unhealthy for normal immune function, normal digestion function, etc.

    we talk about how antiseptic living has increased allergies and other diseases. a clean birthing room might be a part of that constellation of problems. perhaps in the future, healthy child birth will consist of the doctor shoving his finger up the mother's ass and sticking it in the newborn's mouth to ensure full spectrum inoculation. this may sound disgusting to you, but it may be the healthiest thing you can do for a newborn's normal development

    --
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  28. Re:Americans by techhead79 · · Score: 3, Insightful

    This is one thing I always hate to hear. anyone who doesn't really like it simply hasn't been properly introduced. I've know a few Gay men that make the suggestion about certain sexual situations...

    So let me be clear, you're wrong...some things just rub people the wrong way. It's not how you were introduced to it...we are honestly that different from each other. I hate Sushi and it makes me want to throw up just looking at it.

  29. Born with Steril Gut. Get flora from Environment by Anonymous Coward · · Score: 3, Informative

    Primarily the Mother - in cases of vaginal birth. Breastfeeding, touching, etc add more. The infant is pretty well colonized within 1-6 months.
    Wikipedia article on Gut Flora
    http://en.wikipedia.org/wiki/Gut_flora#Acquisition_of_gut_flora_in_human_infants

  30. These Guts Were Made For Sushi... by Radical+Moderate · · Score: 3, Funny

    Cue Nancy Sinatra in 5...4...3...2...1

    --
    Never let a lack of data get in the way of a good rant.