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Animal Farms Are Pumping Up Superbugs

oxide7 writes "The philosopher Frederick Nietzsche once famously said, 'That which does not kill me, makes me stronger.' That may or may not be true for human beings, but it is certainly true for bacteria. The superbugs are among us and they are not leaving. Indeed, they are growing stronger. 'The problem is that the animal agriculture industry makes massive use of low-dose antibiotics for growth promotion and in place of effective infection prevention methods,' Young said, adding that the farm animal population is much larger than the human population. The low-dose antibiotics do not kill the disease. They make the disease stronger, more resistant to those and other antibiotics. The animals — the cattle, pigs and chickens — thus treated become superbug factories. The diseases stay in them and they wash off them to infect the surrounding environment."

75 of 551 comments (clear)

  1. Is this a news? by chiui · · Score: 4, Interesting

    well known fact. And no regulation to stop it.

    --
    Moderation is overrated.
    1. Re:Is this a news? by nedlohs · · Score: 5, Informative

      The article is about proposed regulation stuck in committee to stop it. So apparently it's news for you at least.

    2. Re:Is this a news? by DJ+Jones · · Score: 2, Insightful

      Congress is too busy regulating rulers and paperclips in Science kits.

    3. Re:Is this a news? by nedlohs · · Score: 2, Funny

      For very low values of something...

    4. Re:Is this a news? by commodore64_love · · Score: 5, Insightful

      GOOD. I hope banning antibiotics in livestock passes. Also banning ag companies from accusing innocent farmers of stealing their gene-modified corn.

      This is a perfect example of unintended consequences, where antibiotics cure human disease, but then the germs "fight back" and revive in a more deadly form which we don't know how to stop. I wouldn't be surprised if the 2100s experiences as much death from disease as people in the 1800s did.

      --
      "I disapprove of what you say, but I will defend to the death your right to say it." - historian Evelyn Beatrice Hall
    5. Re:Is this a news? by maxume · · Score: 4, Interesting

      Most of the resistance business is about penicillin derivatives, tetracyclines and vancomycin, all of which come from the 1950s or earlier.

      Sure, misuse is making those antibiotics less effective at treating diseases, but the other half of the equation is that they have been so effective for 50 years that it hasn't been particularly worthwhile to pursue drugs that use different mechanisms of attack.

      Rapid genome sequencing is changing that, expect all sorts of novel antibiotics over the next 20 years. Also expect to pay for them.

      --
      Nerd rage is the funniest rage.
    6. Re:Is this a news? by n6kuy · · Score: 2, Insightful

      Regulate it with your pocket book. Know what you are buying. Don't ask the government to limit liberty in lieu of your own due diligence.

      --
      If you disagree with me on social issues, then it's pretty clear that you are a narrow-minded bigot.
    7. Re:Is this a news? by BrokenHalo · · Score: 4, Interesting

      This is a perfect example of unintended consequences

      It's also a perfect example of stupidity. Human beings haven't really been around that long (in fact, according to some Morm^Hons, I was apparently born before the descent of Man), and evolves comparatively slowly.

      Bacteria, on the other hand, can easily pick up scraps of extracellular DNA and incorporate it into their own, driving evolution effectively (i.e. where necessary) within a single generation of 15 minutes under optimal conditions. Bacteria might not be as smart as us (though I sometimes wonder), but their biochemistry can be seriously cool, and giving them the advantage in our food chain is just damn silly.

      Incidentally, you mention death from disease in the 1800s: It seems to surprise many to be reminded that the Spanish Influenza pandemic (1918-1920) killed more people than the First ("Great") World War. It killed more people in a single year than the Bubonic Plague did in four, from 1347 to 1351.

    8. Re:Is this a news? by h4rr4r · · Score: 3, Insightful

      Considering there are no laws about labeling for that sort of thing how do we do that?

      Clear labeling must be enforced by law.

    9. Re:Is this a news? by commodore64_love · · Score: 4, Informative

      >>>Spanish Influenza pandemic (1918) killed more people than the Bubonic Plague did in four, from 1347 to 1351.

      It's all relative. The 1918 flu killed 3% of the population while the 1348 Black Death killed 45% of Europe and 20% of the world. If WE were hit by some disease with the same mortality as the 1348 bubonic, then 1400 million people would be dead. - Or if it had the same localized impact as it had in 1348, killing 45% of a continent, then 200 million North Americans would need to be buried

      --
      "I disapprove of what you say, but I will defend to the death your right to say it." - historian Evelyn Beatrice Hall
    10. Re:Is this a news? by mcgrew · · Score: 4, Informative

      Influenza is a viral infection, not a bacteriological one. Antibiotics will do absolutely nothng against a viral disease.

    11. Re:Is this a news? by jc42 · · Score: 2, Insightful

      Doesn't the development antibiotic resistant bacteria involve evolution?

      Indeed, and this is occasionally used to illustrate why the evolution/creation "debate" isn't just an intellectual exercise. Here in the US, the creationists have effectively suppressed the teaching of evolution in our school system (below the college level). The result is that most of the population, including the people running all those farms, have been intentionally kept ignorant of the evolutionary process. They don't understand that they're forcing the evolution of antibiotic-resistant micro-organisms. If you were to mention this to them, a lot would react with the standard religious anti-evolution rhetoric, and reject your accusation that they're doing something dangerous. They either "know" that evolution doesn't exist, or they "know" that it takes millions of years and is thus irrelevant to them.

      We're living with the consequences of allowing the religious nut cases to block teaching of the evolutionary process. Or rather, we're getting sick and sometimes dying as a consequence of this.

      Something that doesn't even exist and is just a Jewish conspiracy.

      Heh. I thought Darwin was educated in the Christian ministry. ;-)

      --
      Those who do study history are doomed to stand helplessly by while everyone else repeats it.
    12. Re:Is this a news? by inviolet · · Score: 2, Informative

      Most of the resistance business is about penicillin derivatives, tetracyclines and vancomycin, all of which come from the 1950s or earlier.

      Your conclusion is missing a vital piece of data. Vancomycin is the last line of defense for antibiotic-resistant infections in humans. That is why doctors avoid using it -- because it is vitally important that the bugs never acquire a resistance to it.

      I remember a few years ago, when the industrial-farming folks pushed through approval to use vanco in cattle feed. The physicians in attendance made the obvious objection, and naturally were ignored in favor of the farms' colossal political power. Yee-haw, full speed ahead!

      --
      FATMOUSE + YOU = FATMOUSE
    13. Re:Is this a news? by jc42 · · Score: 2, Interesting

      There was a story on /. here a few years ago about squirrels that look booth ways before crossing the road.

      Yeah, I've seen them doing that. Of course, since their eyes are on the sides of their heads, it's pretty easy for them. But you can see them looking around for things in the street.

      One of my favorite examples of short-term human-triggered evolution is in our lawn: Our neighborhood has mower-adapted dandelions. This has been reported in many cities, but rarely out in rural areas where mowers are much less common. What they do is form flowers on very short stems that are below the mower blades. Then, as the seeds ripen, the stem grows to the usual longer length, so the mover tears up the seed head and sends (some of) the seeds into the air and on their way. The seeds' little "parachutes" are also somewhat tougher than they used to be.

      There are lots of other example of wild critters, weeds, and parasites adapting quickly to human activity. The squirrel and dandelion adaptations are mostly funny illustrations. Bacterial adaptations to antibiotics aren't quite as entertaining.
       

      --
      Those who do study history are doomed to stand helplessly by while everyone else repeats it.
  2. I have an idea to stop the need for anti-biotics by SirGeek · · Score: 4, Interesting

    How about we feed the animals the foods they were DESIGNED to eat (i.e. Feed Cows GRASS, Not Corn). Yes, the grass might cost more but you wouldn't need to pump them full of antibiotics.

  3. Re:I have an idea to stop the need for anti-biotic by robably · · Score: 5, Insightful

    How about we feed the animals the foods they were DESIGNED to eat

    Even better, feed them the food they have EVOLVED to eat.

  4. Re:It is all your fault by aliquis · · Score: 2

    I'm vegan, if you drink milk you're still supporting it ;)

    Anyhow, afaik cows and such don't get antibotics for no reason over here in Sweden. Sure if they get sick (I don't know how that affect slaughter though, don't know if you sell the meat if they are on drugs.)

    So it's an american (and most likely others) thing.

    May be more needed in really small boxes where you can't move at all and everyone is closer to eachother and so on.

  5. What about... by chiui · · Score: 2, Insightful

    using no antibiotics and killing the diseased animals? In the long rung they would get superanimals :)

    --
    Moderation is overrated.
  6. Re:I have an idea to stop the need for anti-biotic by Anonymous Coward · · Score: 2, Insightful

    You'd still have to pump them full of antibiotics.
    The environment they are in tends to be pretty bad due to trying to pack as many animals together as possible to increase profit by lowering costs.

    Doubtless having animals eat the kinds of food they should actually be eating would help the situation some, though, as it would remove some of the needs for antibiotics and artificial diet balancers.

  7. no shocker by TheCarp · · Score: 4, Interesting

    I mean, anyone who has not had their head stuck in the ground for the past 30 years should be well aware of the whole antibiotics/superbug issue. The only possible exceptions being the evolution deniers and, I bet even many of them have some twisted concept that reconciles their philosophy with superbugs.

    However, I was reading that there is a new class of antibiotics in development, which are based on immune system antigens and, for some reason (anyone know more?) are thought to, because of their mechanism of action, not be susceptible to the same problem of evolving the bacteria to survive them.

    I don't know if its true or how they work but, if the article I saw a while back is right, then, they could be useful here. Then again, this just seems like a bad idea overall.

    -Steve

    --
    "I opened my eyes, and everything went dark again"
    1. Re:no shocker by llamapater · · Score: 2, Interesting

      that sounds like it could go very wrong if bacteria evolves to counter that and it mimics the bodies natural immune system we as a species may well be fucked

    2. Re:no shocker by Raenex · · Score: 2, Informative

      They believe in small scale evolution (the electricity), but they don't believe in large scale evolution where a single-cell organism has evolved into all the species that you see today. At least, not based on purely random mutation. It's kind of hard to repeat that in the lab.

  8. Corporate Farming and Capitalist Failure by al0ha · · Score: 4, Interesting

    Occasionally I get to drive by a huge corporate cattle ranch while on a trip; the animal's living conditions are deplorable. No shade in a hot arid climate, and hardly enough room to move around, they pack as many animals into a corral as possible. They stand all day in wet muddy shit, costs too much to provide land to roam and people to round them up.

    In my opinion, this exemplifies what is wrong with unabashed Capitalism. Who cares what happens, just make us more money now, is a philosophy ultimately doomed to failure. Time to get smart.

    --
    Did you ever wake up in the morning, with a Zombie Woof behind your eyes? -- FZ
    1. Re:Corporate Farming and Capitalist Failure by MyLongNickName · · Score: 4, Insightful

      Actually, it is not what is wrong with Capitalism. This is what is called an externality. Basically a unaccounted for benefit or cost. The role of government is to see things like this that the market cannot account for and be sure to tax or regulate according to the cost.

      It isn't terribly difficult. The problem is we have the right with their Pavlovian "Government is bad" chant, and the left which wants to micromanage. You then have the majority of the population which doesn't really understand economics and just listens to their favorite commentator think for them.

      --
      See my journal for slashdot ID's by year. Mine created in 2005. http://slashdot.org/journal/289875/slashdot-ids-by-year
    2. Re:Corporate Farming and Capitalist Failure by Fastolfe · · Score: 2, Insightful

      I don't understand what this has to do with Capitalism. Can you describe some other type of economy that would not result in the same outcome? The real problem is that efficiency in cattle ranching is at odds with your sense of decent living conditions for these animals. Any system that rewards efficiency and does not adequately protect the animals will have this outcome. The solution is to regulate how animals are treated and their living conditions. Or, at the very least, have a certification and labeling program to allow consumers the option of only purchasing from ranches that meet their personal standards.

    3. Re:Corporate Farming and Capitalist Failure by llZENll · · Score: 3, Informative

      Food Inc I watched it last year and made the switch to eating about 95% organic ever since. I tell people we are in the FOOD MATRIX right now, everyone is, when I go to a normal grocery store now all I see are the green 1 and 0s of the matrix code on the isle shelves, except instead of 1s and 0s they are processed corn, soy, and wheat lol. If people only knew, or cared to know. Watch this movie and you will know some of it, its sad, but you can help change it. Sadly it takes a long time as the mass market of buying is the uneducated, and getting this message to them is very hard.

    4. Re:Corporate Farming and Capitalist Failure by Abcd1234 · · Score: 4, Insightful

      Actually, it is not what is wrong with Capitalism.

      What? It's exactly what's wrong with capitalism. Hell, you pointed out the problem yourself! Negative externalities are *specifically* a fundamental flaw in pure capitalism, which is why it must be tempered with some level of government intervention.

    5. Re:Corporate Farming and Capitalist Failure by rsborg · · Score: 4, Insightful

      Basically a unaccounted for benefit or cost. The role of government is to see things like this that the market cannot account for and be sure to tax or regulate according to the cost.

      This is exactly the definition of "Unbridled" Capitalism (ie, free from the government "bridle). I agree with you that it's in the common interest that capitalism is regulated, and the government is the best tool for that job.

      Our major problem isn't with the people who are brainwashed into "free markets == victory" mantra, but the brainwashers (ie, the corporate controlled media) and the money that pays everything and everyone to buy into that flawed concept.

      The wealthy and corporate elite are the ultimate villains here, they will do what they did to other countries where they strip-mined the land, put the people into slave labor, in the name of pure profits.

      We in the US/EU ignored it then because we benefited from it, but now it's coming back to bite us because these multinational corporations and their controlling funders are now more powerful than governments and have quite a few in their pockets. World domination won't come through the flawed UN, but instead through the "invisible hand" that controls and dominates numerous governments across the globe into doing it's bidding.

      --
      Make sure everyone's vote counts: Verified Voting
  9. Re:I have an idea to stop the need for anti-biotic by Stargoat · · Score: 2, Insightful

    If you would have RTFA, you would realize that the animals are being pumped full of antibiotics to increase size, not to keep them disease free.

    --
    Hoist Number One and Number Six.
  10. Re:I have an idea to stop the need for anti-biotic by Red+Flayer · · Score: 3, Informative

    The reason it increases their size is because it keeps them disease-free.

    Livestock stressed by illness don't grow as fast.

    --
    "Trolls they were, but filled with the evil will of their master: a fell race..." -- J.R.R. Tolkien on Olog-hai
  11. I work cattle part-time. It's a real threat. by Anonymous Coward · · Score: 3, Informative

    The usual anti-biotics we used was from a Pfizer product labeled LA-200 and it is expensive at around $140 every 5-ounces: about 1/4 ounce is used for a 350lb cow when we find one with a puncture wound or laceration. I've talked with smaller family farms on what they use on their animals to prevent infections and fight infections and it's always been a simple herbal formula consisting of crushed garlic mixed with crushed black walnut and applied as a paste that is more effective than Pfizer LA-200. Ive tried this same organic mix on fungal infections on my forearms and llower legs and it works better than the expensive tube pastes from convenience stores.

    What I find unsettling about LA-200 is that many of the cowboys equally take a smaller dosage by the same needle (before using on the cows though) because it's practically the same as what they would've been given from an HMO but much less expense.

  12. I am not a vegetarian, but we need to reduce by dominion · · Score: 5, Interesting

    I am not a vegetarian, but we need to reduce our meat consumption. I'll never be a vegetarian, I'm too fond of my Sicilian-American culinary traditions, but two things need to happen: First, we need to reduce the amount of meat we consume, and we need to consume better meat when we do. This diet that America has of eating a big bucket of meat and cheese from Denny's is just ridiculous, and it's killing us on multiple fronts.

    I try to follow a basic plan: Vegan (or Vegetarian) before 6pm. I try and make sure the meat I do eat for dinner is high quality. I pay a little extra for it, but the savings throughout the day balance out. There are other types of diets that would be great for reducing meat consumption without any of us thinking we're suddenly living off of soy and wheat germ. Eating smaller portions of meat, but still using it for flavoring, for instance. Even just getting the idea in our heads that we shouldn't eat meat for every single meal.

    Factory farming has got to go, it's horrible on so many fronts. I'm not a foodie, and I don't have vegan super powers, and I recognize that people are on a budget, and can't shop for organic at whole foods (hell, I can't afford to, and I have a decent job). But we have to figure some kind of practical way forward, because we can't keep packing animals in to dark crates, standing in their own filth and pumping them full of drugs and then call that dinner.

  13. buy organic by t2t10 · · Score: 2, Informative

    It will be a long time before Congress acts, if ever. But you can protect yourself and make things better by buying meat from "organically" raised animals: animals that were raised without antibiotics and without having been raised in factory farms. Note that the "organic" label itself may be misleading depending on what you are and who uses it, so check more carefully what it means for that particular product (the label usually says it if they did go through the trouble of doing the right thing). You should also probably avoid genetically modified animals, foods, and feeds, not because the genetic modifications are harmful (usually they are not), but because many genetic modifications are intended just to enable bad and dangerous farming practices. Both of these are in your own interest (not just socially good things to do) because you yourself may run a higher risk of infection with a resistant strain if you eat animals raised on antibiotics.

    1. Re:Buy organic by icebraining · · Score: 2, Insightful

      Too bad that "organic" is an overloaded term with not clear definition, especially in the realm of the food industry.

    2. Re:buy organic by ThatOtherGuy435 · · Score: 2, Informative

      Most places in the country have Community Supported Agriculture (CSA) programs, and it well behooves one to look into these.

      I get about 15-25lbs of fresh produce, locally grown by a group of Amish farmers, every week - and it costs me about $15/wk and a half hour on Saturday running up to the local farmer's market to pick it up. Some places have the same kind of thing for grass-fed beef and (genuinely) free range chicken, and occasionally pork too.

    3. Re:Buy organic by Anonymous Coward · · Score: 2, Informative

      Actually "organic" has a clear definition, particularly in the realm of the food industry.

      The United States passed legislation defining what "Organic" actually means back in 2002.

      http://www.ams.usda.gov/AMSv1.0/ams.fetchTemplateData.do?template=TemplateA&navID=NationalOrganicProgram&leftNav=NationalOrganicProgram&page=NOPNationalOrganicProgramHome&acct=AMSPW

      I'm not sure exactly how it applies to meat, however products that say they are "Organic" need to be made with 95% organic ingredients. I tried to look up exactly what organic meat was through through the USDA website however didn't make much progress.

      I do know however that the certification process to be classified as organic is a pretty serious thing to go through. I've heard it is cost prohibitive to smaller farms.

    4. Re:Buy organic by stonewallred · · Score: 3, Informative

      Fuck that. Take a few cigarettes, break off the filters and drop them into a bottle of water for about two or three days. Spray some of that water upon the bug of your choosing. Watch as the bug goes into a long, painful looking death spasm, imagining the agony as its body is poisoned. And what amazes me is that I use this mixture on some plants I grow in order to control mites, and I still smoke a pack or two a day.

  14. Re:It is all your fault (fyi this is a joke) by T+Murphy · · Score: 4, Funny

    You vegetarians want to save the animals, but we carnivores are doing our part to cut down on this superbug problem. If we listened to you vegetarians, these animal farms would be a huge drain on the economy, raising animals for no practical use, and the animal population would spiral out of control. Stop shifting the blame and take responsibility to this disaster you're creating.

  15. Re:Growth? What? by t2t10 · · Score: 2, Informative

    Nobody knows for certain, but it does work. (If it didn't work, agribusiness wouldn't be spending so much money on it.) It's probably that it's normal for animals to get bacterial infections, and while they are fighting them, they aren't eating and growing as much. If you can eliminate most of those infections, they will just grow without interruption, meaning they will grow bigger over the same time period.

  16. Well... no by sean.peters · · Score: 2, Informative

    Actually, while there are a lot of theories (some of which are discussed in other responses), no one really knows why. It's not really curing any disease... antibiotics make even healthy animals grow faster. So actual answer to your question is no, no one can really explain this.

  17. Re:Growth? What? by geekoid · · Score: 2, Insightful

    They help animals digest there food more efficiently. For example, about 5% of the food a pig eats would normally lost to the bacteria in the digestive tracks.

    --
    The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
  18. Re:1) buy out local traditional family farms by TheLink · · Score: 2, Informative

    5) slaughter livestock, grind up by products, then feed to other livestock.

    That bit also happens unhygienically - very often the animal feces and bacteria get splattered everywhere contaminating the meat.

    Then the consumers are told to cook everything properly, and if stuff happens, it's the consumer's fault, not agribusiness fault...

    I've heard of a case where they dunk all the chicken in the same water after removing the feathers, and naturally that mixes and spreads all the bacteria and gunk from all chickens...

    --
  19. Re:Growth? What? by pspahn · · Score: 2, Insightful

    Watch a documentary or two. Animals raised in an environment where they aren't exposed to typical bugs don't develop the same strong immune system as animals exposed to these things since birth. Imagine you were born in a box and lived your whole life in that box. After some time your immune system would become suppressed and you would need this stuff to survive.

    This reminds me of a study I once read about (I think it was done in Germany) where they looked at the immune systems of children raised on farms and were regularly exposed to livestock. They compared this to the immune systems of children raised in an urban setting and found that kids who grow up with regular exposure to animals had a stronger immune system. Same concept.

    I like to eat animals, but it is troubling to know the truth about how they are raised. I feel fortunate to live in a region where it is possible to raise animals in a less manufactured way.

    --
    Someone flopped a steamer in the gene pool.
  20. The "superbugs" aren't stronger by Attila+Dimedici · · Score: 2, Insightful

    The summary gets one thing wrong. Antibiotic resistant bacteria are not stronger than those that are nor antibiotic resistant. As a matter of fact they are weaker. Generally, the way that bacteria develop resistance to antibiotics is by shutting down the cellular mechanism that the antibiotic uses to get into the cell. However, that cellular mechanism serves a useful function in the cell (usually to bring nutrients into the bacterial cell). When antibiotic resistant bacteria are in an environment without antibiotics they generally die off over a relatively short time-span. This is why currently most infections with antibiotic resistant bacteria occur in hospitals.
    That being said, excessive use of antibiotics is still a bad thing.

    --
    The truth is that all men having power ought to be mistrusted. James Madison
    1. Re:The "superbugs" aren't stronger by crmarvin42 · · Score: 4, Informative

      Conventional wisdom agrees with you, but the evidence does not. Denmark has had a ban on growth promoting antibiotics for almost a decade now, with the rest of the EU having followed suit only a couple of years later. Several antibiotics that have been approved for use the US were never approved for use in the EU for agriculture. However, they were approved for use in humans. DANMAP is the danish antibiotic use and resistance tracking program that was developed to ensure compliance and track the ban's effect. I can't remember off the top of my head, but for several of those antibiotics that were never approved for animals, but were in humans, the resistance levels are higher in Denmark, then they are in the US where agriculture has been using them alongside human medicine. It appears as though many antibiotic resistance genes have no negative value in the absence of selective pressure, which goes a long way toward explaining the generally higher resistance levels in some EU member nations relative to the US.

      This is a very important and complex issue, and FUD articles like the IBTimes one are not helpful. They stir up the general populace to act without considering the evidence that already exists. The EU ban has not been effective at its stated goal of reducing resistance prevalence in the human population. I think that a ban that excludes the nursery phase would be more appropriate if not a complete repeal of the ban. But that's just based on my own interpretation of the scientific literature (as opposed to the financial literature, or populist literature). You can agree with me or not, it won't affect my research.

      --
      Bureaucracy expands to meet the needs of the expanding bureaucracy.-Oscar Wilde
    2. Re:The "superbugs" aren't stronger by Guppy · · Score: 2, Informative

      The summary gets one thing wrong. Antibiotic resistant bacteria are not stronger than those that are nor antibiotic resistant. As a matter of fact they are weaker. Generally, the way that bacteria develop resistance to antibiotics is by shutting down the cellular mechanism that the antibiotic uses to get into the cell. However, that cellular mechanism serves a useful function in the cell (usually to bring nutrients into the bacterial cell). When antibiotic resistant bacteria are in an environment without antibiotics they generally die off over a relatively short time-span.

      Eh, "-1 Oversimplified".

      Loss-of-function or alterations of form are indeed one of of the possible mechanisms, and tends to be the more easily-evolved type, so you will often see those appear (and disappear) the fastest. However, occasionally you see mutations that are "free" to the bug, and represent a genuine evolutionary advance that will stick around, possibly forever.

      Outside of this, resistance mechanisms are mostly plasmid-encoded factors for things such as antibiotic-degrading enzymes, efflux pumps, and other such defenses. The evolutionary cost for these can range from very high to trivially low, depending (does your enzyme soak up lots of resources to make, or is it highly efficient? Is it permanently switched on, or does it come with an induction mechanism that only triggers when appropriate?). In addition, many bacteria can swap plasmids around, allowing for more genetic versatility.

      So the short answer is, that there is no short answer. How fast resistance disappears when antibiotics are no longer used, will depend on each particular situation. However, over time quick-and-dirty solutions will tend to be replaced by more evolutionarily elegant adaptations.

  21. Re:I have an idea to stop the need for anti-biotic by maxume · · Score: 2, Informative

    The USDA prohibits feeding mammal tissues to ruminants.

    That still leaves them room to feed chicken to cattle though.

    --
    Nerd rage is the funniest rage.
  22. Re:Growth? What? by gstoddart · · Score: 2, Informative

    Can someone explain to me how giving animals antibiotics promotes growth of the animals?

    Basically, they use them as a broad-spectrum prophylactic against things that might otherwise affect them and make them less productive/healthy animals.

    Essentially to compensate for industrial farming practices which are more or less awful conditions (cows enclosed in a stall standing in their own shit for hours at a stretch) they inoculate them against everything. They're also feeding them stuff that would make you cringe ... mad cow came from feeding sheep-parts (brains) to the cows (herbivores) for instance to put more protein in their diet. The prions in the sheep brain crossed into the cow in a way that would never have happened without people intervening -- when was the last time you saw a bunch of cows standing around the carcass of a sheep?

    Small scale farming (the way it was done for thousands of years) didn't have these problems because the conditions were different. Yes, cows could still get sick, and probably did. But, people weren't putting them in unsanitary conditions and feeding them part of other animals.

    The antibiotics help to mitigate (in a non-specific way) some of the effects.

    --
    Lost at C:>. Found at C.
  23. Re:I have an idea to stop the need for anti-biotic by 0100010001010011 · · Score: 3, Interesting

    Some people still do. It's not something you can get at Walmart but if you live anywhere close to the country there is a good chance that:
    1) There are farmers markets around. The best and freshest produce and meat money can buy, and usually competitive on price.
    2) Some farmers let you just buy a side of a cow (or an entire cow). So for $x00 you can buy an entire cow. The farmer raises it, kills it and you can have a say in how it is butchered. This does require a deep freezer (unless you're going to throw one heck of a braai). Usually ends up cheaper than super market and you know exactly where your meat is coming from.

    Cut out the middle man.

  24. Some info by geekoid · · Score: 3, Insightful

    1) the animals use a very low, non therapeutic dose, most of which is lost in their waste.
    2) there isn't any good evidence that this causes superbugs. Yes, intuitively it seems so, and there may be a mechanisim in place, and it really wouldn't surprise anyone if this turned out to be the case, but no study backs any of that up.
    3) it is now that the over use of therapeutic doses causes this issue.
    4) not all bugs become superbugs
    5) superbug doesn't mean more virulent.

    Now:
    We need to understand the precise mechanism on how the antibiotics work for growth. The exact chemical reaction. Then we can produce more specific drugs.

    We should be using the Swedish model. Slightly less product per animal. I I don't think a 1% increase in meat costs is going to be a big deal to any individual persons budget

    --
    The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    1. Re:Some info by tpjunkie · · Score: 2, Informative

      1) This is precisely the "best" possible way to induce antibiotic resistance. You are basically selecting out the bacteria which are able to tolerate low doses of antibiotic, which are then able to outcompete their more susceptible brethren. The result is the "normal" gut flora of these farm animals now has a built in resistance to that particular antibiotic. 2) The gut flora of these animals is excreted in waste. The mechanisms by which super bugs are created is through transmission of plasmids, bacteriophages, and naked DNA uptake, which many species of bacteria are capable of. (For a new fun threat, see http://en.wikipedia.org/wiki/Vancomycin-resistant_enterococcus ) 3) There is no "therapeutic dose" for healthy animals. Antibiotics are given to animals to increase the rate at which they absorb food. The "normal" state of the lamina propria and mucosa of the gut is a constant state of low level inflammation, which serves as a protection from any bugs that manage to work their way out of the lumen of the gut. Antibiotic use lowers the amount of gut flora, likely leading to a reduction in this inflammation that results in greater absorption of food. I am not aware of a conclusive proof of this, but animals raised in sterile conditions and fed sterilized food support this hypothesis in terms of weight gain and histologic appearance of gut tissue. 4) You don't need all bugs to become super bugs. The majority of bacteria can become much more virulent and resistant to antibiotics. It really only takes one or two, and there are nearly innumerable options that live happily as commensals in either our or other species guts. 5) This is true, but it's not really going to cheer up someone whose opportunistic infection is resistant to antibiotics. Anyway, see #3 for a good idea of the mechanism. It's not a chemical reaction, its a physiologic consequence. FWIW, I am a medical student finishing up microbiology.

  25. Re:I have an idea to stop the need for anti-biotic by russotto · · Score: 2, Insightful

    Evolution is an automated design process with a more complete specification than manual engineering.

    Eh? Evolution has no specification and only one requirement: Survive to reproduce.

  26. Organic food isn't just for hippies anymore... by defro · · Score: 2, Informative

    Speaking of hippies, I stopped by my token hippy friend's place the other day and they were watching this documentary about food. It was called Food Inc. and after literally the first 5 minutes, I planted myself on the couch and watched it. I always knew our (ie. us Westerners) diet was pretty bad, but I really had no idea HOW bad the food system is. We're basically eating crap 24/7.

    Long story short, I've been reading up about this topic lately and can suggest a few easily accessible resources for anyone who wants to learn a bit more:
    Food Inc. - A decent documentary to get you started.
    The Omnivores Dilemma - An easy read that can point in the right direction for further research.

  27. http://www.foodincmovie.com by Anonymous Coward · · Score: 2, Interesting

    http://www.foodincmovie.com

  28. The superstition of the market by Un+pobre+guey · · Score: 4, Interesting

    This is not a bad example of the superstitious fallacy that market forces fix everything, and we should deregulate all markets because regulations only get in the way, blah blah blah. Feedlots exist because in the short term they are by far most efficient from the strict standpoint of profitability. They are monstrously inefficient overall because they externalize the costs of waste disposal, coliform contamination of meat, feed costs (corn, the favorite animal feed, is subsidized), high fat-content in the resulting meat (due to the use of corn instead of forage), etc. The public must bear these costs so that meat producers can enjoy a profitable business. The power of the market is largely a myth that exists mainly in academic discussions rather than in real life.

  29. What's really scary is... by Philomage · · Score: 2, Insightful

    ...the uncontrolled experiment in microbe evolution being conducted in workplaces all over North America. In my own workplace there are these sanitation stations on every floor, in every wing, that dispense alcohol gel. Thousands of people everyday, in my complex alone, depopulate the flora and fauna of their hands to let the evolutionary lottery pick new winners to see what develops. I truly fear for the future of humanity.

  30. Re:Um, then stop it! by Abcd1234 · · Score: 2, Insightful

    People are blindly following the sciences, and that's a huge problem.

    Yeah, here's a little hint: People blindly doing anything without considering the long-term consequences will likely fuck shit up. At least science provides us with the necessary tools to predict and evaluate those consequences.

    I mean, you don't *really* think this whole "livestock superbug" thing is suddenly a new, entirely unpredicted discovery, do you?

  31. catch 22 for the small farmer by Anonymous Coward · · Score: 4, Interesting

    disclaimer, I raise some cattle

    This whole scene with the huge feedlots is a ripoff for the consumer and the end user eater..and for us small farmers. We only have a hand full of big packers in the US. Small farmers are forced to sell their feeder cattle at auction, because it is SO difficult to market full size eatin cows locally. It's possible, but mostly it just sucks, almost impossible People just don't have full size freezers anymore where they can fit a "side" or half a cow. So, we are forced to sell the cows at a lower weight, typically around 500-600 lbs at auction, for a suck ass cheap price, so the very few corporate buyers get them and ship them to the feedlots where they are fattened up like you describe in medium rank conditions. They have basically a ripoff cartel that sets prices. We as small farmers don't make much at all, most of the loot is made upstream at the packers and then the shippers, then with the wall street speculators who make a *ton* for doing nothing at all except being leeches. That $8.99 1lb ribeye you are eating we got paid around a buck for...maybe

    If more people would buy locally, we could change this. Our cows are grass fed and happy, plenty of room to move around, shade, all of that. What happens after the auction is out of our hands. You as consumers can change this, buy local, spend the money and get a decent sized freezer, you will get much cheaper beef and better quality.

  32. Re:I have an idea to stop the need for anti-biotic by SuricouRaven · · Score: 2, Insightful

    Cows are partially designed. Many domesticated species differ greatly from their wild ancestors. Cows included. Chickens too. Pigs a little, but not so much. Bananas are an extreme example.

  33. Phages, possible solution? by Firethorn · · Score: 3, Informative

    However, I was reading that there is a new class of antibiotics in development, which are based on immune system antigens and, for some reason (anyone know more?) are thought to, because of their mechanism of action, not be susceptible to the same problem of evolving the bacteria to survive them.

    I liked what the Russians were working on for a while - Phages. More completely, Bacteriophages. Viruses for bacterias.

    No chance of the virus crossing over to affect humans, and a bacterial colony already under assault by the human immune system isn't generally going to last long when it's also 'sick' with a virus. As a bonus, immunity doesn't really happen because the virus adapts right along with the bacteria.

    The problem with phages is that they're the opposite of broad-spectrum antibiotics. They're very, very, specific. They'll clear a throat infection right up, but first you need a culture to determine which species of bacteria you have(there's millions/billions of them), then find an effective phage against it.

    That can take a week, then you gotta get the phage to the clinic, as most don't have the room for the number of phage samples you'd need.

    --
    I don't read AC A human right
    1. Re:Phages, possible solution? by Firethorn · · Score: 2, Interesting

      Until they mutate. Which is where they came from in the first place.

      Probably way back when multicellular life was just differentiating itself from other forms of proto-bacteria.

      The mutations necessary to be infectious in a mammal's cell versus a bacerial cell is just too extreme to be a credible threat.

      --
      I don't read AC A human right
  34. Re:I have an idea to stop the need for anti-biotic by h4rr4r · · Score: 2, Interesting

    Including chicken litter, which may include undigested chicken feed, which includes mammal tissues. Producers voluntarily stopped using chicken litter as cattle feed recently, but could go back to using it at any time.

  35. Since when... by crmarvin42 · · Score: 5, Informative

    is the International Business Times an authority on anything. I'd never even heard from them before today.

    Additionally, as someone with a doctorate in animal science and a researcher in the field, I have to say that the case against animal agriculture is overstated. No one will argue that they don't contribute, but the relative importance of antibiotic use in animals (that less than 1% of the population ever come into contact with while they are alive) relative to that of rampant, large-dose, antibiotic abuses in hospitals (You know where all of those sick people hang out, transferring infections back and forth) has never been ascertained empirically.

    First, the vast majority of the bacterial species that live in livestock are not capable of living in people. Therefore, the rate of resistance transfer from animal bacteria to human bacteria is relatively low. Evidence exists that these species can, and do transfer resistance gene between eachother. However, the majority of the evidence is "Resistance gene A is present in pig bacteria and human bacteria, and genes are essentially identical, therefore the gene came from animals!" This of course, completely ignores the possiblity that the gene arose to prominence in the human population and then was transferred to a pig via a farm worker that was a carrier. Talk about placing the cart in front of horse.

    Second, low levels of antibiotic use in the swine industry is usually only during the first month after weaning. Pigs are weaned at between 18 and 24 days on most farms in order to prevent the sow (aka "Mom") from transmitting certain diseases to the piglets that have little effect on adult animals, but can kill piglets very easily. At this age the maternal antibodies from the colostrum are starting to wear off, but the piglets own acquired immune system is not completely up to the task. Therefore the antibiotics buy the piglets time by reducing the overall microbial load in the intestine, and coincidentally increasing the efficiency of feed utilization (which is good for the environment). Many farms then discontinue the use of prophylactic, or growth promoting antibiotics because antibiotics cost money and feed costs can account for 60-70% of total production overhead. Expensive feed can drive you out of business in a hurry.

    Third, to all those bragging about being from the EU, where there is a total ban on prophylactic antibiotics a word of caution. The total amount of antibiotics used in EU agriculture is not actually lower than it was before the ban. The difference is that instead of giving antibiotics to prevent infection, and improve production they are now given to tread disease outbreaks that wouldn't of otherwise happened and to try and minimize reductions in production. Also, the antibiotics of most relevance to human medicine are not routinely used for growth promotion, but they are used to treat disease outbreaks. So, the total tonnage of antibiotics being administered has not really gone down (it did until they banned them in the nursery which was the last phase of the ban), and the antibiotics being used are MORE likely to also be used in human medicine. Bravo, talk about unintended consequences!

    Finally, I fail to see how this made the front page here. It is not the usual fare of geek (no computers anywhere), it is not actually news (this controversy has been around for at least a decade), this article contributed nothing new to the discussion (restates already rampant FUD), and the IBTimes are not exactly the NYTimes or LATimes. The only thing I can see in its favor is that it lets the ignorant "Organic" group say I told you so without any real technical points for those few of us in the field to respond to. The original article is link-bait, plain and simple and /. fell for it.

    Pathetic

    --
    Bureaucracy expands to meet the needs of the expanding bureaucracy.-Oscar Wilde
    1. Re:Since when... by Fantastic+Lad · · Score: 2, Interesting

      You bring up some valid points and your insight is an appreciated antidote to a poorly executed article.

      But (putting GM feed aside), there remains one big aspect about factory farms I cannot get past...

      Are the animals experiencing a quality of life which doesn't include standing around in shit?

      Then they are no longer animals. They are active meat cultures. They may not be stressed, but I know plenty of fat idiots who are generally not stressed either and their lives are also pathetic compared to free range humans. When driving past factory chicken farms, the air for a mile in every direction is filled with the stench of hell. Life existing the center of that hell may not be overly stressed, but it's still not the right place for living things. And I do imagine that egg laying chickens stacked in boxes, despite any efforts to mitigate their stress levels don't experience what one might call "sanguine" lives. Same goes for milking cows to a lesser degree, but only because you can't stack ruminants.

      I know this doesn't fit well into the question, "Well, how do you propose we feed all these people?" While there are better ways, better diets, and better means for managing populations of both humans and farm animals, the fact remains, we are where we are and it isn't pretty.

      So what can I do? Well, I eat free range and I know my farmers and I've met the herds and the birds. I'm satisfied that I'm not contributing unduly to lousy lives among our fellow creatures occupying this world. Can this scale up to meet the present needs of the planet? I doubt it. We're pretty much screwed as a population. But that doesn't mean I have to play along. I'm not going to cause needless misery and degradation if I can avoid it. And if everybody had cared enough from the outset, I'm sure we could have built a far better system which respected the creatures who feed us as they deserve.

      There's a ton of bad karma being generated and it will need to be paid back eventually. It always is.

      -FL

    2. Re:Since when... by crmarvin42 · · Score: 2, Informative

      Most of my recent experience is with pigs, and broiler chickens, but I did work on a couple of small to medium sized dairies as an undergraduate. On intensive dairies, the cows live in a free stall barn usually. They consist of 1 or 2 ally's flanked by rows of stalls. The stalls are elevated about a foot or 2 above the floor, are padded (ground up tires cover with thick canvas and fresh wood shavings replaced periodically), and allow the cows to comfortably lie down without laying in shit. On one wall is a headlock system where the cows can poke their heads through to reach the feed. The headlocks prevent one cow from pushing another cow away from the feeder, and can be set to hold the cows in place when they need medical treatment. At the end of the ally's is a large open space that lead to the milking parlor (of which there are multiple designs, each with benefits and drawbacks of their own) which they enter for milking. They are fed and milked 2 to 3 times a day. Dry cows and replacement heifers are kept separate from the milking animals because their nutritional needs are so different so they just have a free stall barn without the milking parlor.

      Beef can be raised out on the range, in free stall barns, or in feedlots. I have little direct experience there, so I can't tell you much more detail. However, I can be certain that their conditions are not as abhorent as most people believe because the stress of poor environment inhibits animal growth, production, and quality. Bad farmers put themselves out of business the next time prices drop.

      --
      Bureaucracy expands to meet the needs of the expanding bureaucracy.-Oscar Wilde
  36. Re:I have an idea to stop the need for anti-biotic by h4rr4r · · Score: 2, Informative

    Pork fat, pastry is made with lard. Not tallow. That would be horrible.

    Oh and stop using Crisco, that stuff sucks. Mix butter and lard 50/50 if you must.

  37. Re:1) buy out local traditional family farms by MozeeToby · · Score: 3, Insightful

    3) pipe sewage to huge waste ponds, then spew it out onto open ground. To hell with the neighbors who complain about the smell

    It's not a waste pond, it's 100% all natural fertilizer storage the type of which has been in use since humanity began farming, including by those family farms you imagine were run so differently. The alternative is to spread artificial petroleum based fertilizer on everything or not be able to farm the same field after about 10 years. So yeah, to hell with the neighbors who complain about the smell, they don't know what they're talking about.

  38. Re:I have an idea to stop the need for anti-biotic by hoggoth · · Score: 5, Interesting

    THIS!

    I (we) buy all of our food directly from farms. We live in a suburb of New York City, and still we have found farms not too far away.
    We buy a 1/4 cow (we split it with three other families) and it feeds us for a year. All of our produce comes from farms as well.
    Our beef and chicken is raised walking around eating grass and bugs and whatever it would naturally eat.

    The food tastes better and is better for us.
    A month doesn't go by that I don't hear of some horrible contamination-caused food recall that doesn't affect me or my family.

    --
    - For the complete works of Shakespeare: cat /dev/random (may take some time)
  39. Re:I have an idea to stop the need for anti-biotic by JonySuede · · Score: 2, Insightful

    so stop buying the cheapest meat as possible

    --
    Jehovah be praised, Oracle was not selected
  40. Re:It is all your fault by shadowofwind · · Score: 3, Funny

    As a vegetarian....

    Actually, you know, I can't think what to write next.

    Lack of protein and/or necessary combinations of amino acids does that to one's cognitive abilities. Try mixing mushrooms with lima beans. And eat more nuts and sprouts.

  41. Re:I have an idea to stop the need for anti-biotic by hoggoth · · Score: 4, Informative

    We are both partially right. From http://www.fao.org/docrep/article/agrippa/555_en.htm

    According to the National Office of Animal Health (NOAH, 2001), antibiotic growth promoters are used to "help growing animals digest their food more efficiently, get maximum benefit from it and allow them to develop into strong and healthy individuals". Although the mechanism underpinning their action is unclear, t is believed that the antibiotics suppress sensitive populations of bacteria in the intestines. It has been estimated that as much as 6 per cent of the net energy in the pig diet could be lost due to microbial fermentation in the intestine (Jensen, 1998). If the microbial population could be better controlled, it is possible that the lost energy could be diverted to growth.

    Thomke & Elwinger (1998) hypothesize that cytokines released during the immune response may also stimulate the release of catabolic hormones, which would reduce muscle mass. Therefore a reduction in gastrointestinal infections would result in the subsequent increase in muscle weight. Whatever the mechanism of action, the result of the use of growth promoters is an improvement in daily growth rates between 1 and 10 per cent resulting in meat of a better quality, with less fat and increased protein content. There can be no doubt that growth promoters are effective; Prescott & Baggot (1993), however, sho ed that the effects of growth promoters were much more noticeable in sick animals and those housed in cramped, unhygienic conditions.

    Currently, there is controversy surrounding the use of growth promoters for animals destined for meat production, as overuse of any antibiotic over a period of time may lead to the local bacterial populations becoming resistant to the antibiotic. This is it not an invariable rule: Streptococcus pyogenes remains sensitive to penicillins after over sixty years of clinical use but such examples are, however, very rare. Undoubtedly, the medical exploitation of antimicrobial chemotherapy, particularly to treat human infections, has imposed an enormous selection pressure on formerly sensitive bacteria to acquire genetic elements that code for resistance to antibiotics.

    --
    - For the complete works of Shakespeare: cat /dev/random (may take some time)
  42. Re:gah. by treeves · · Score: 2, Funny

    ...more expensive beef might be a good thing.

    Most definitely! Have you had Kobe beef? MMmmmm.

    --
    ...the future crusty old bastards are already drinking the Kool-Aid.
  43. Re:It is all your fault (fyi this is a joke) by morari · · Score: 2, Informative

    That's not how survival of the fittest works though. ;)

    --
    "He who can destroy a thing, controls a thing." --Paul Atreides, Dune
  44. Re:I have an idea to stop the need for anti-biotic by jc42 · · Score: 2, Insightful

    Gawd, not this/i unimaginative debate again. ... why can't a "Universal Awareness" (I dislike the word "God," to me it sounds so ass-backward and presumptuous) have used "evolution" to influence "design?"

    Actually, in this case that's what people were talking about. Except the "design" wasn't done by a [Gg]od. It was done by a million local animal breeders over thousands of years, who started with a number of wild animals, and through selective breeding, produced the modern milk/egg/meat machines that give us most of our protein.

    Similar selective breeding was done by other millions of growers to produce our modern grains, some of which are so different from their wild ancestors that we're not sure just which wild species were the ancestors.

    However our domesticated animal and plant species came to be, we know a fair amount about how they turned into the current species. There was a good deal of "intelligent design" in this process. Urban stereotypes of dumb rural hicks aside, many of those millions of growers and breeders did know what they were doing and how they wanted their animals and crops to change.

    --
    Those who do study history are doomed to stand helplessly by while everyone else repeats it.
  45. Re:How about free market? by Cyberax · · Score: 2

    Yes, in fact bureaucrats do have a better track record than for-profit companies.