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Fighting Mosquitoes With GM Mosquitoes

doug141 writes "Scientists are releasing genetically modified male mosquitoes that produce flightless female offspring. The male offspring go on to wipe out another generation of females. This is similar to the way screwworms were eradicated in the U.S., except with nature itself making more of the modified males. Field trials are already underway."

18 of 521 comments (clear)

  1. Nature... will find a way! by arcite · · Score: 5, Informative

    Or maybe not. Actually I would be more in favor of releasing wave after wave of bats. Fruit bats preferably, they're cute!

    1. Re:Nature... will find a way! by ascrewloose · · Score: 4, Informative

      At least the fruit bats won't starve if we kill all the mosquitoes.

    2. Re:Nature... will find a way! by jcgam69 · · Score: 3, Informative

      Except for the occasion rabies infection: http://www.sciencedaily.com/releases/2002/05/020506074445.htm

    3. Re:Nature... will find a way! by icebike · · Score: 4, Informative

      Be careful what you wish for. There was an article - google it - regarding the number of bats killed by wind turbines and the direct cost increase to farmers who had to increase their pesticide usage in response.

      Sorry, but that is totally false myth perpetrated by anti-wind power crowd. Modern wind turbines do not kill birds or bats in any great numbers. Ask any farmer who walks around under the turbines on his land. Ask Google.

      --
      Sig Battery depleted. Reverting to safe mode.
  2. Mosquitoes will go the way of the dinosaur! by bogaboga · · Score: 3, Informative

    What could possibly go wrong?

    The mosquito could become extinct in a few generations. Here's how this could play out:

    Mosquitoes usually fly when fleeing danger. These flightless mosquitoes will not be in position to flee! In a situation where they could survive a whack by flying away, they will surely be killed!

    Killed in enough numbers, there will be no female mosquitoes to produce the 'next generation!'

    Result: Males will find it difficult to find a mate, resulting in fewer mosquitoes all together.

    Folks, the mosquito could get extinct in a few years. Scary indeed.

    1. Re:Mosquitoes will go the way of the dinosaur! by Bowling+Moses · · Score: 5, Informative

      "Folks, the mosquito could get extinct in a few years. Scary indeed."

      Well, A mosquito species could be come extinct. According to TFA, Aedes aegypti to be exact. This particular mosquito can carry several major human pathogens including dengue hemorrhagic fever, yellow fever, and chickungunya, which are all viral diseases. Ae. aegypti originated in Africa but is now found throughout tropical and subtropical regions including the USA, where it used to be in only Florida and the southeast but has since spread north to New York and Illinois. Especially alarming is the fact that there have been outbreaks of dengue recently (in 2010 at least) in Florida.

      Eradication of Ae. aegypti might not necessarily be that big of a deal environmentally. While mosquitoes are an important part of the diet of many predators, there are over 40 genera comprising thousands of species of mosquitoes. Any reasonably sized chunk of land probably has more than one species of mosquito, for example here in Wisconsin we have not less than 58 species. Even tiny Rhode Island is home to at least 46 mosquito species!

    2. Re:Mosquitoes will go the way of the dinosaur! by Bowling+Moses · · Score: 4, Informative

      Male mosquitoes feed on nectar from flowers, in the lab we feed them sugar water. Female mosquitoes on the other hand require a blood meal for the proper development of their eggs. Mosquitoes live in the water as free swimming larvae, which will develop into similarly free-swimming pupae. When development is complete, the pupae floats to the water surface and the adult mosquito emerges. The adult mosquito stands on the water surface while its new exoskeleton and wings dry and harden. The adult mosquito can't swim, and while it can walk on water it only does so when emerging from the pupae and for some species when depositing eggs. It minimizes water walking in both cases and flies away as soon as possible. That's what makes this so cool. The female, and only the female mosquito, is stuck on the water unable to fly and practically motionless. It's a free lunch to any mosquito-eating predator around. The males on the other hand are free to escape and then free to mate and pass that gene on to their offspring--again fatal to their daughters, and no harm to their sons, who repeat the cycle.

    3. Re:Mosquitoes will go the way of the dinosaur! by bryan1945 · · Score: 3, Informative

      Many many years ago I read a study that determined that the only species that could go poof and it wouldn't matter was the mosquito. It wasn't this one, but it said more or less the same thing-
      http://www.nature.com/news/2010/100721/full/466432a.html

      --
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  3. Re:Obligatory turd in punchbowl by Taibhsear · · Score: 4, Informative

    Since clearly a lot of people didn't read the article or the link in the article that directly addresses this...

  4. Re:Obligatory turd in punchbowl by Anonymous Coward · · Score: 4, Informative

    I found this on the Internet.

    http://www.nature.com/news/2010/100721/full/466432a.html

    [[Ecology: A world without mosquitoes

    Eradicating any organism would have serious consequences for ecosystems — wouldn't it? Not when it comes to mosquitoes, finds Janet Fang.]]

  5. Re:Lets fuck it up. by TheCarp · · Score: 3, Informative

    Partially agreed but...at the same time... who knows what doesn't mean it wont work...or will result in problems later, just that we don't fully know...and I might argue, can't fully know until we try.

    That said, I think it has a real chance of working, mostly because of how drastic of an effect this could have by shifting the reproductive cycle in such a way as to massively overpopulate males vs females. If this works for the first few generations, it could quickly put a hurting on their numbers. This leaves a couple of possibilities.

    Actually.... this reminds me of some of the talk of cancer evolution....in fact, its probably a good model here. To go from being a human cell to a cancer cell generally takes not just one, but several evolutionary steps. At each of those steps, a cell line could die off (either via chance or via a cleaning mechanism designed to take out mutated cells). Chances are, if you have cancer, your body came close to cancer several times before one cell finally finds the right mutated configuration.

    So the chance of developing cancer actually is dependent on the number of steps required to become cancerous, down all of the paths that it can. This is an identical situation here.... it comes down to how close the populations genetic makeup is to being able to circumvent this. If it only takes one or two mutations to make females who avoid GM males, or to produce something which compensates for the change, then.... this is unlikely to work. Similarly, if they already have the genes required to make females that are not susceptible, then this will simply make sure that they dominate.

    That said, if there are no coping mechanisms already in their population, and if developing them is more than a few mutations away.... it could come damned close to eradicating them. Once their numbers are vastly smaller, it would also slow the rate of total mutations in their population, making them less likely to make it over the hurdles.

    It could work.... but... what that will mean in the long term is unclear.

    --
    "I opened my eyes, and everything went dark again"
  6. Re:Obligatory turd in punchbowl by Remus+Shepherd · · Score: 3, Informative

    The article links to this Nature story that asserts that completely eradicating mosquitos would have no measurable effect on the environment. They don't really do anything but spread disease. They might have a role as a food source for other animals, but they don't appear to be very significant.

    But we might be missing an important part of the chain, and wiping out the mosquitos might throw the world completely out of balance. Then again, humans have so many reasons to hate the little buggers that it still might be worth it.

    --
    Genocide Man -- Life is funny. Death is funnier. Mass murder can be hilarious.
  7. Re:How about driving their evolution instead? by Rerracoon · · Score: 3, Informative

    That's exactly what they are doing. They are concentrating on one single strain of mosquito that is the only one that carries the virus. by eradicating only this one strain, they hope to eliminate the virus without eliminating the Mosquito as a species.

  8. Re:Genocide by geekoid · · Score: 4, Informative

    It's a new disease, so I expect you haven't heard of it: Malaria.

    malaria accounts for 2% of deaths worldwide. most of which are children.

    and secondly:RTFuckingA. the discuss that specific topic.

    --
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  9. Some info on malaria by Nidi62 · · Score: 3, Informative

    MALARIA FACTS Of the 300-500 million clinical cases of malaria that occur globally each year, 90 percent of them are in Africa. Malaria is endemic in more than 90 countries. Forty percent of the world population is at risk for malaria. Ten percent of world population gets sick each year with malaria. DEATH BY MALARIA Number of fatal cases of malaria each year: over 1 million Most common age at death: 4 years Every 30 seconds, a child dies of malaria Five percent of African children are killed by malaria, almost 3,000 each day, or the equivalent of seven jumbo jets full of children crashing every day. Up to 23 percent of African infants are born with the malaria parasite.

    (http://malaria.jhsph.edu/about_malaria/)

    Personally, I think killing large numbers of mosquitoes is a good thing, especially considering malaria is quickly becoming resistant to the drugs used to treat it. A reduction in mosquito numbers would greatly reduce the transmission of this disease.

    --
    The only thing necessary for evil to triumph is for it to be pitted against a slightly greater evil
  10. Re:Obligatory turd in punchbowl by Anonymous Coward · · Score: 2, Informative

    Like, for instance, humans. Nature would get along much better without us, probably.

    My theory is that nature wanted plastics, and since there was no natural way to produce plastics nature created humans to make plastics. Unfortunately for nature this plan has gone slightly had some unforeseen side effects.

    Thats George Carlins hypothesis.

  11. Re:Lets fuck it up. by mark-t · · Score: 4, Informative

    The immediate side effect is that there will not be any mosquitoes.

    No serious negative repercussions are known to exist for such an event beyond that the diet of certain types of insect predators would be affected (fortunately for such predators, their diet is not exclusively dependent on the species of mosquito that this concept intends to render extinct). The net effect upon mankind should be positive, other than possibly causing companies that make mosquito repellent to possibly go out of business.

    But seriously.... did you *NEED* somebody to have to spell that all out for you? They're mosquitoes, for crying out loud... and not some vital part of the food chain on which we ourselves are part of.

  12. Re:Obligatory turd in punchbowl by kEnder242 · · Score: 3, Informative

    http://www.scientificamerican.com/article.cfm?id=the-wipeout-gene&page=6

    "Some people wonder if it is ethical—or safe—to eliminate an organism, even in just a small geographic area. Proponents argue that A. aegypti is an invasive species that has evolved to exploit a solely human niche. “Urban A. aegypti is not part of any significant food chain,” says Phil Lounibos, a mosquito ecologist at the Florida Medical Entomology Laboratory. Yet Lounibos doubts whether eliminating A. aegypti would stop dengue transmission permanently. “A previous campaign to eradicate this species from the Americas in the 1950s and 1960s, when it was the primary vector of urban yellow fever, failed miserably,” he says. The invasive Asian tiger mosquito—another good dengue vector—readily occupies niches vacated by A. aegypti. Moreover, both the Cayman and Tapachula mosquito strains, even if successful, are not permanent. Migration of mosquitoes from neighboring regions into Tapachula could foil eradication attempts and mandate frequent releases of the modified males to keep the population in check."

    --
    my associative arrays can kick your hash - TCL