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HIV Vaccine Approval For Human Trials
An anonymous reader writes with news that researchers from the University of Western Ontario have been given approval from the U.S. Food and Drug Administration to begin testing an HIV vaccine in humans. From the article:
"The vaccine is the first based on a genetically modified killed whole virus, [researchers said.] ... a clinical trial on 40 HIV-positive volunteers will begin next month. That phase will last a year, after which 600 HIV-negative volunteers will see how the vaccine impacts their immune systems. A final phase, which will take about three years, will involve about 6,000 HIV-negative volunteers."
WOOHOOO!!!
So it is a kill -9 virus?
So the pool will longer be closed due to AIDS?
Pretty sure this means that they know it works but want to see if it fucks anything else up?
I hope this vaccine is as effective as the smallpox and polio vaccines have been. The world would do well to be rid of this particularly crafty and deadly virus. It is also a whole lot easier to introduce vaccination programs into third world countries (which counts as medicinal treatment) which would otherwise have severe religious problems with contraceptives like condoms (which counts as interfering with "God's work").
- Toast
to get someone to let you inject them with an experimental vaccine for a deadly virus? Is there a clause in the contract for a lifetime supply of AZT should the vaccine's quality control be lacking and the test subject contracts HIV? I've always been curious how this stage of research is handled.
0mg
Who's the HIV negative subject going to get injected with a Vaccine that could possibly cause HIV? It technically is possible.
"Ok, so you either were injected with the actual vaccine or the placebo. Go have sex with this shady hooker to see if it worked!"
There is no such virus, the acquired immune syndrome has always existed for certain types of bedroom activity. But then again that would prevent people from perpetuating the lie that a condom prevents this, and so the lie persists in a certain type of doctor.
The purpose of existence is to make money.
Alright, fine! I'll go back to lurking on Fark...
There is no sig...
Trial 1: One year.
Trial 2: Length unspecified, but probably one year.
Trial 3: Three years.
Add in about six months per trial for paperwork, awaiting new approval and so on... six and a half years.
This had better be good.
Interesting point to consider though. If the trials were conducted with reckless disregard for the safety of the test subjects, trials one and two could be eliminated. That saves three years, at the expense of perhaps killing a few of the volunteers in the remaining trial. If the vaccine makes it to practical use three years earlier though, that would be a lot more additional lives saved. Could more people be saved overall by considering testing volunteers semi-expendable in order to hasten medical advance?
You can even have another Toronto paper if you like.
Good to hear that this is going forward. Hopefully, this will lead to a brighter future for Africa.
I worry about the health of the participants, but, HIV isn't a death sentence anymore. I would volunteer for the trial, assuming that, in the worst case, they cover my medical expenses and anti-retrovirals to control it.
It would be worth it.
Let's hope this line of research dampens the damage being done by the pro-circumcision lobby's dubious attempt to present circumcision as a viable tool for preventing HIV.
Can we work on that next?
This isn't just positive news, its HIV positive.
Why does a Canadian University need approval from the U.S. FDA?
WALSTIB!
I guess the FDA has to make sure the drug is truly safe, after all. At least all those people who will contract and die of AIDS over the next four years will die safely.
Liberty in your lifetime
Why does this sound like a plot from a horror movie?
The Year: 2012
The month:Dec
The vaccine being tested does not work. It instead causes the virus to further mutate into an airborne variety
Result: Those fearing 2012 were correct. A Global pandemic....
And the residents of Habbo Hotel express cautious optimism over a future where the pool is no longer closed due to AIDS.
How long until this vaccine is mandatory for 2 year olds?
I figure, if it passes clinical trials, 5 years later we'll require every toddler to have it before they can attend pre-school. (Got to stop all that pre-school sex.)
delivers the goods.
Seeing aids go from you are going to die, to testing a vaccine in 25 years is freaknig awesome.
The Kruger Dunning explains most post on
Back in college I would frequently get paid to be a test subject for medical research (to test for, say, metabolizing rates of a blood pressure medicine, etc); it was a fantastic way to help pay for school, and my grandmother was proud to tell everyone that I was "helping out the medical research community". The WORST was a concurrent heroin trial, where all the subjects were easily identified as "those guys puking in the toilets all day long"...and yes they were compensated. That being said, I cannot imagine how much they'd have to pay me to examine my body's reaction to an HIV vaccine....!
wait till everyone realizes that once AIDS is "cured by prevention" they'll eventually have to deal with the millions that are infected with Lyme Disease who've been ignored, chastized, marginalized and left to suffer for so long. Sex with monkeys will seem downright religious.
Now that we're messing with "God's plan" for people. (sarcasm)
So in the clinical trials, do some of the volunteers NOT get the actual vaccine? It seems like you have to validate its effectiveness against something... but giving people a placebo instead of an actual vaccine against a life-threatening disease seems sort of dodgy...
"Well, none of them got HIV, if that's what you're asking."
Now we can go back to eating raw monkey meat like god intended. Just don't forget that dipping sauce!
Please do not read this sig. Thank you.
Killed whole virus means whole virus if mistakes are made. I had a co-worker who spent several weeks in the hospital several decades ago that got shot with a still "hot" vaccine. Oops.
Having sex with animals exclusively means you'll never contract a human STD (unless you hotswap the animal with another human) and any zoonosis can happen without sex.
What is it, a shot of vitamins? Oh, genetically modified whole killed virus, really? Have they published an actual report with evidence proving the existence of whatever virus that is, first? Because without that I think I'd hold them and their snake-oil, premature claims to success, under considerable incredulity!
And what's this? A final phase to be tested on 6,000 clean individuals? Over three years? Perfect, enough time for a super retro-whammy-insane-O version of HIV to quietly spread into the population. What with the low numbers they've been seeing thanks to more easily available information, numbers of HIV cases have decreased and with scientists making huge strdes tiwards new, legitimate cures in the last couple of years, we might actually be looking at the end of AIDS. That's no good, how will Gallo and his cohorts continue to make billions pushing poisons? This whole injecting people with super HIV is a GREAT idea!
"Stratigraphically the origin of agriculture and thermonuclear destruction will appear essentially simultaneous" -- Lee
You might just get it.
Just saying, why would FDA have anything to do with a Canadian trial?
I, for one, welcome our new pharmaceutical overlords.
SO how do they do the final testing of the vaccine?
They are starting human trials, but does that mean that eventually they are going to give this vaccine to someone and then inject them with HIV and see what happens?
How much money do you pay patients to be injected with a deadly virus that you "think" that you have a vaccine for now.
Troll is not a replacement for I disagree.
Why is Phase I testing the vaccine on people that are HIV positive? A vaccine is a preventative measure it is not a cure so it won't have any effect on people that already have HIV. So why test it on them? Anyone?
Comment removed based on user account deletion
Please see: http://www.petermcwilliams.info/health-scams/86-the-aids-hoax
the zombie apocalypse is upon us
It's still an inoculation. Vaccines have never once been created by a pharmaceutical corporation for the betterment of the people. A supplement to the Immune System would make an awesome vaccine, such as antigens or even a boost synthetic White cell, but giving the disease and expecting it to train your Immune System is the reason why the fatality and complication statistics have been skewed. Not to mention the dangerous delivery of this HIV inoculation doesn't meet the character of being a vaccine: it's a live virus, no matter whether you call it crippled or what. I haven't even mentioned the fact that it's delivery by syringe is one of the primary reasons it is dangerous in that the blood stream will circulate something in your body within a matter of minutes while a swab for only a localised inoculation would keep it a complication of a limb that can be pinched-off (sounds funny, but it's on the mind).
I myself have survived 2 heart attacks in early 2000's on a MMR "vaccine" that turned out to be the real-thing for me. That was 2 heart attacks that I KNOW ABOUT because I was awake, yet I have had the same symptoms countless times after awaking in pain from sleep and mind-numbing effects. Those heart attacks were never my main concern: it was the dreadfull allergies and auto-immune complications that followed and I didn't even equate them to anything but my high maintenance lifestyle of long-distance jogging and weight-lifting.
I've gotten more Immune System training from drinking water to small amounts of urine of someone that survived said viral infection and this gave me the antigen recovery for train my Immune System the right way without the Black Bag and the Needle. Does everyone forget that many of these so-called "vaccines" were result of military testing in which soldiers in high-stress environments signed-over their lives to be the expendable guards against foreign principalities while the military industrial complex was having raunchy COMMERCIAL SEX with Big Pharma to trade and train the testbed for germ warfare weapon advantage? That was the case of H5N1 in Ukraine that was traced to a mishandling from Baxter Laboratories as being the maker of that Germ Warfare agent. However if H5N1 was named for a Germ Warfare agent then why was that form and strain of virus not linked to H4N1 and the others prior? That's BULLSHIT that the public needs to know. H5N1 was remedied by the local population without Big Pharma, without Kaiser Permanents: but with raw minced garlic consumed readily multiple times per day with food and that alone not Inoculations disguised as vaccines is what conquered every virus including the Germ Warfare H5N1 strain.
I hope all of these participants are watched very carefully.
It would be pretty stupid if one of them contracted AIDS and then passed it on to someone, and then that someone passed it on to someone else , etc etc etc..
it isn't good to buy any kind of product from a company whose own government has a financial impact and incentive to approve such a product that could spawn future job security if either weren't held liable for any discovered complications.
Remember that these kinds of companies get WAIVERS from the government to dispense this tech without liability for what harm it causes. That's the opposite of a warrantee: that's a weapon.
The reason diseases spread is because people are uncloaked on a hostil planet of such infections that spread by contact to eachother. Goverment police manhandles everyone on the road but come to the jail and they put on gloves and cower at what secrets they reveal in their inquisition. People are worth more dead from such forced simulated moral decisions as vaccination, because money transfering hands involunarily through death is the game of Trust law that catalyzes society into it's effeminate downward spiral.
Diseases don't spread to islands because the boat is isolation enough, and the smartest people are already in motorcycle suits under helmets to hide their resperator bong to be ready to get some oxygen when they feel the resulting PH imbalance and cramping that results from a spreading infection.
So how much does everyone think this is going to cost? The largest group of people that have HIV/AIDS live in Africa and are very very poor. Who gets first dibs on this? Obviously the wealthy, but what can be done for the extremely poor?
Africans still rape and dissect virgin living albino Africans on claims that such non-melanized African can cure AIDS or give good luck in business and fishing.
Africans still are known as enduring among fellow Africans where RAPE is a weapon by conquering troops that is unlimited to grown men as punnishment for dessertion and children and women to muster submittance and to babies as punnishment against existing family.
And here we see on Slashdot that supposes the probability of bestiality by Africans as being the intent to malign Africans more than they already admit theirselves to be? In al depravity, Germany and Rome was the center of much vile filth and yet published knowledge of this goes unrestricted yet when someone publishes anything on Africa that continues to this day thousands of years beyond it is all suddenly an eschewing of circumstance or racism?
OH PLEASE: Africans already have the reputation of being both cruel and cowardly, and if bestiality ever was part of their character then it would actually be positive because they would defend the animal they love more than their harrem of underrage girls.
FUCK YOU, OP.
Because it's a US trial. The vaccine was developed in Canada, but they're doing the trial in the US, presumably as people meeting the trial criteria (HIV negative people at high risk of infection) are easier to come by, if only due to having 10x as many people.
upon the advice of my lawyer, i have no sig at this time
At this point would be a tremendous boon to the human race.
Don't worry, there will be plenty of breeders left, more than enough.
From the headline and summary, you'd almost think this was the first-ever HIV vaccine approved for human trials, but that's far, far, far from the truth. Really the only story here is that it's the first Canadian-developed vaccine approved for human trials. http://www.hvtn.org/science/trials.html
You know what I find disturbing is the fact that the government helped craft/fund the above supposed vaccine and yet private industry ends up with the patents.
What about something like this?
http://www.msnbc.msn.com/id/41834106/ns/health-aids/t/gene-therapy-builds-hope-future-aids-cure/
http://www.wired.com/wiredscience/2008/06/gene-editing-co/
I truly believe from the bottom of my heart and in the deepest reaches of my soul, that in order to solve the AIDS problem, we need to get rid of the faggots.
Perhaps its better to judge from case to case, instead of generalizations.
Sometimes a hard decision is necessary, a compromise has to be made.
But sometimes the price is just too horrible and unthinkable, indeed.
Cargill: [gets out five files] Well, I've narrowed your choices down to 5 unthinkable options. Each will cause untold misery and--
President: [points to the third file] I pick #3.
Cargill: You don't even wanna read them first?
President: I was elected to lead, not to read. #3!
I am opposed to HIV vaccine, because HIV infection is the result of a personal sins, i.e. fornication. Negro mount monkeys and then eat them, white men sleep with men like they should sleep with womenfolk, the japanese abuse the dignity of the female body in their pervert-oriented porn culture. "Emancipated" housewives invite husbands to their rear entrance when he complains of untight pussy. Teenage party girls openly offer their body for serial copulation after bilge drinking sprees and street women sell their bodies for drugs and thus HIV spreads.
Do not eat monkeys and apes, do not engage in animal sex, do not practice homosexuality and refrain from analsex or pornography. Do not copulate with prostitutes, do not abuse drugs and do not fornicate. Value marriage as a bond for life, raise your children to be God-fearing and wholesome and thus HIV/AIDS will be soon gone.
Thus spoke the Lord of Abraham, God jealous, who punishes the sins of fathers in their sons for up to the 7th generation!
Why does a Canadian organisation require any permission from the Government of the USA?
Heavy is the head that wears the tinfoil hat.
Basically any decently powerful medication goes all batty on side effects because of the body's irritating habit of requiring some 5-70 interactions to get anything done. So it's only 3rd generation medicines etc that get the job done right because of 20 years of practice. My own minor hobby is studying stomach acid preventers. (Not cheap calcium rolaids etc, the other pills that are supposed to prevent your stomach from overproducing the acid in the first place.)
The first gen ones did work, but over-targeted related biochem targets, so they didn't play nice with a whole slew of important prescription meds. Only later by switching around the component molecule rings did the newer ones mostly behave.
My first Journal Entry ever, in 8 years! http://slashdot.org/journal/365947/aphelion-scifi-fantasy-horror-poetry-webzine
Does this mean we can have sex with monkeys again?
And gay men will become less fatalist?
Seriously. I'd volunteer. I'm 51, not married, no dependents, HIV-negative. If the vaccine fails, so be it. If it works, many lives could be saved.
My brother died of AIDS in the early 90s. Most nurses were afraid to touch him. Health insurance wouldn't cover him. Politically, it was leprosy.
I'd volunteer because the sooner a cure/vaccine is found, the better it is for the world.
I'm sure this has been mentioned, but one presumes that there are two primary tests:
A) does the vaccine have side effects & what are they
B) does the vaccine work.
In order to answer B, doesn't this mean you have to find someone without HIV, administer the vaccine, and then expose them to HIV?
Being a volunteer ... for this ... damn. That takes nuts.
Your comment confuses me for the following reasons:
Ceviche *is* cooked. (The proteins are denatured with acid rather than heat.)
Venison is *not* monkey. (Not even moderately related as far as species go.)
Steak/Horse/Venison/etc Tartar (a raw chopped preparation) can be exceptionally tasty with no cooking whatsoever.