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Aspirin Helps Prevent Cancer, New Studies Show

kkleiner writes "For years, research has shown that aspirin is beneficial in preventing heart attacks. Now new studies support its ability to prevent cancer as well. The studies, involving tens of thousands of participants over many decades, show reductions of cancer incidence (both short- and long-term) and mortality rate as well as a decrease in metastatic cancer. It still is not known exactly how aspirin and cancer are connected, but those between the ages of 45-50 will now likely consider taking low-dose aspirin daily for the remainder of their lives."

21 of 132 comments (clear)

  1. Goddamn Futurism "Reporting" by eldavojohn · · Score: 5, Informative

    100-Year Old Wonder Drug Now Shown To Prevent Cancer and Heart Attacks

    Hmmm, that's odd, this "news" story reads like one of those ads trying to sell me something. Is this ancient Chinese secret or midwest housewife research?

    For all the money spent on studies of aspirin, perhaps all the evidence anyone needs of its health benefits is the life of Walter Breuning, who lived to be 114 years old and aspirin was the only medication he ever took.

    Oh, you just need a sample size of one? No need for that expensive tens of thousands double blind study, huh? And all he ever took was aspirin? We should refuse vaccines? And what the hell do you mean by "for all that money spent"? I find it odd that all three of the abstracts linked to in the article end with:

    Funding
    None.

    Wait a second ... *checks URL*

    singularityhub.com

    Oh son of a bitch, it's more misinformation and half truths from Ray Kurzweil's disciples. Now I have to guess which is which.

    --
    My work here is dung.
    1. Re:Goddamn Futurism "Reporting" by Jeremiah+Cornelius · · Score: 5, Funny

      "perhaps all the evidence anyone needs of its health benefits..."

      Well, my grandmother relied exclusively on anecdotal evidence, and SHE lived to be 103!

      --
      "Flyin' in just a sweet place,
      Never been known to fail..."
    2. Re:Goddamn Futurism "Reporting" by mcgrew · · Score: 4, Informative

      Hmmm, that's odd, this "news" story reads like one of those ads trying to sell me something. Is this ancient Chinese secret or midwest housewife research?

      Neither, it was on TV news last night. It's a peer-reviewed study with unexpected results. Here are a couple of more reputable sources than the stupid FA that I didn't bother reading:

      Can aspirin really reduce the risk of cancer?
      Studies Link Daily Doses of Aspirin to Reduced Risk of Cancer

      Unfortunately, many folks seem to pick the least reputable rag they can find as a link for their submissions, often their own blogs.

      Aspirin isn't for everyone. Kids under 16 shouldn't take it, especially if they have the flu, and if you have stomach or digestive problems, hemophilia, or a few other conditions aspirin can be dangerous.

      I wonder if Naproxin Sodium prevents cancer? I stopped taking aspirin when the patent on Alieve went away.

    3. Re:Goddamn Futurism "Reporting" by hrvatska · · Score: 5, Informative

      100-Year Old Wonder Drug Now Shown To Prevent Cancer and Heart Attacks

      Hmmm, that's odd, this "news" story reads like one of those ads trying to sell me something. Is this ancient Chinese secret or midwest housewife research?

      Maybe you like it straight from 'The Lancet': Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials, Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials, and Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials.

      The NY Times also reported on these studies. Some of the findings of these studies found were that after five years the risk of dying of cancer was reduced by 37 percent among those taking daily aspirin, that over six and a half years, on average, daily aspirin use reduced the risk of metastatic cancer by 36 percent and the risk of adenocarcinomas by 46 percent, daily aspirin use reduced the risk of progressing to metastatic disease in patients with colorectal cancer.

      It was found that the risk of bleeding in aspirin users diminished over time, and that the risk of death from brain bleeds was actually lower in the aspirin users than in the comparison group.

    4. Re:Goddamn Futurism "Reporting" by ColdWetDog · · Score: 4, Insightful

      This has been going on for years - low dose aspirin either helps or it doesn't help.

      Here's a couple of take home messages - the canonical study would be to see if low dose aspirin helps you live longer (live 'better' would be a much more useful metric, but pretty much impossible to do). IIRC, the studies that looked at that did not find any benefit from aspirin.

      Second - all of these aspirin / cancer link studies have been pulled from aspirin and heart disease studies - these were secondary effects and the studies neither designed nor powered to ask whether or not aspirin was useful for cancer prevention. When you do this, you are pretty much at the mercy of people who purport to understand statistics much better than the vast majority of folks. Lies, damned lies and .... statistics.

      And finally, when you see reports that a certain drug / treatment / lifestyle does or does not work over a number of various and sundry studies, it means that the value of the treatment / drug / lifestyle isn't all that much. In other words, the effect is just barely over the noise floor.

      Don't worry about it, you're gonna die anyway.

      --
      Faster! Faster! Faster would be better!
    5. Re:Goddamn Futurism "Reporting" by Mister+Whirly · · Score: 4, Informative

      Naproxen Sodium is not to be taken daily for a long term or it can cause kidney problems. I know someone who found this out the hard way after taking it daily for over a year. Maybe she should have read the warning about consulting a doctor about long term use and the directions to stop taking it after two weeks.

      --
      "But this one goes to 11!"
    6. Re:Goddamn Futurism "Reporting" by Anonymous Coward · · Score: 5, Funny

      Don't worry about it, you're gonna die anyway.

      The evidence speaks against it. In all the time I lived, I've died exactly zero times. Therefore the experiment "will I die this second" has a huge about of evidence against (typical science experiments are data-starved in comparison!), the number of repetitions being larger than a billion, all with the same result: "No". Therefore I conclude that I'll never die. :-)

  2. Contraceptive. by wcrowe · · Score: 5, Funny

    It's also a good contraceptive, according to Rush Limbaugh.

    --
    Proverbs 21:19
    1. Re:Contraceptive. by Jeremiah+Cornelius · · Score: 5, Funny

      I'd like to establish a control set for Rush's experiment. I beleive that it is actually his "personality" which is the mechanism preventing fertilization.

      --
      "Flyin' in just a sweet place,
      Never been known to fail..."
  3. Re:But destroys your liver by XxtraLarGe · · Score: 5, Informative

    I'd rather avoid aspirin and other NSAIDs (like tylenol/acetaminophen).

    But then again...

    A 2009 article published by the Journal of Clinical Investigation suggested that aspirin might prevent liver damage.

    Source: http://en.wikipedia.org/wiki/Aspirin#Experimental

    --
    Taking guns away from the 99% gives the 1% 100% of the power.
  4. It's not misinformation by pigwiggle · · Score: 5, Informative

    it's actual, real life, scientific research - published in a well read and respected peer reviewed medical journal. But if it's just the messenger that has you all wee weed up, try PBS
    http://www.pbs.org/newshour/bb/health/jan-june12/aspirin_03-21.html

    --
    46 & 2
    1. Re:It's not misinformation by Tokolosh · · Score: 4, Informative
      --
      Prove anything by multiplying Huge Number times Tiny Number
  5. Re:But destroys your liver by Daniel+Dvorkin · · Score: 5, Informative

    I'd rather avoid aspirin and other NSAIDs (like tylenol/acetaminophen).

    Acetaminophen's not an NSAID, since it has hardly any anti-inflammatory effect at all. Still something that should IMO be avoided -- aspirin's actually a lot healthier and safer for most people -- but it's important to know what class of drugs you're actually dealing with.

    --
    The correlation between ignorance of statistics and using "correlation is not causation" as an argument is close to 1.
  6. I'm for it. by Cazekiel · · Score: 4, Funny

    I was thinking of quitting smoking. Now I'll just take an aspirin with every cig. Problem solved!

    --
    You want to know how to help your kids? LEAVE THEM THE F*&K ALONE. --George Carlin
  7. The Study Itself Is Fine, Singularity Hub Is Not by eldavojohn · · Score: 4, Insightful

    it's actual, real life, scientific research - published in a well read and respected peer reviewed medical journal.

    I've got no problem with the original research being legit. I have a problem with the original research showing that for this historical data it statistically linked aspirin to reducing the risk of cancer. It didn't show that these people who took aspirin were also more likely to take supplemental vitamins nor did it attempt to show exactly how the aspirin worked its "miracle." Was there a control group? You have to understand that the reason I'm "wee weeing" (whatever the hell that means) singularity hub is that they took totally legit level headed scientific research and they jumped all the way up to this:

    100-Year Old Wonder Drug Now Shown To Prevent Cancer and Heart Attacks

    Now let me ask you, where in the research did it "show" in anyway how this prevents cancer? And the article itself was only worse. It's a statistical study on historical data and from your PBS link, they did it right:

    How Aspirin May Help Prevent Certain Kinds of Cancer

    Do you see the difference here? These singularists or futurists or whatever the hell you want to call them take this, which is like 50% and bump it all the way up to 100% and make it a universal truth. Then they extoll this about how they're living until the end of time and people get caught up in this. It's ridiculous and, yes, I'm going to call this out when I see it. I do call that half-truths and I do call that misinformation. We can be more clear about this and the people PBS interview are.

    That part about the 114 year old man? That wasn't misinformation? The lead in that that was all you need? I was out of line to get annoyed by that?

    --
    My work here is dung.
  8. Aspirin's mechanism of action IS known! by Invisible+Now · · Score: 5, Informative

    The mechanism, at least for colon cancer is known. Aspirin is COX 2 inhibitor. Colon and other cancers have COX 2 receptors on their cell walls. See details at: http://modernrecovery.com/news/7-latest/11-aspirin-reduces-colon-cancer.html

    --

    "Knowing everything doesn't help..."

  9. Inflammation by koan · · Score: 4, Informative

    There are doctors that are going as far as to state that most ailments (heart disease, cancer, arthritis, etc) are cause to some degree by chronic inflammation:
    GIFY
    https://encrypted.google.com/search?client=ubuntu&channel=fs&q=inflammation+and+disease&ie=utf-8&oe=utf-8

    Aspirin reduces inflammation and so helps in all things inflammation related.

    You should check out diet related inflammation as some (if not most) of us have poor dietary habits OR eat to much.
    https://en.wikipedia.org/wiki/Inflammation

    --
    "If any question why we died, Tell them because our fathers lied."
  10. Re:But destroys your liver by fahrbot-bot · · Score: 4, Informative

    Acetaminophen's not an NSAID,

    Furthermore, as far as I know, it's only Acetaminophen (Tylenol) that has been shown to potentially cause liver failure using regular 2 x 325mg doses, and only when taken with alcohol over a period of a few days. The articles I've read about liver failure from NSAIDs have been from using high(er) doses of Ibuprofen or Naproxen - both of which are stronger than Aspirin - continuously over a long period of time, like for arthritis pain control. But, IANAMD.

    --
    It must have been something you assimilated. . . .
  11. Re:But destroys your liver by Hatta · · Score: 4, Informative

    Aspirin is not harmless either. About 10,000 Americans a year suffer gastric bleeding due to aspirin. There is absolutely a tradeoff to be made here. Don't go on aspirin therapy without fully considering the risks.

    --
    Give me Classic Slashdot or give me death!
  12. Re:The Study Itself Is Fine, Singularity Hub Is No by krotkruton · · Score: 4, Interesting

    I agree with you on a lot of points, but this study was more than just another correlation study like those that link high levels of vitamin D in subjects to reduced risks in cancer. This was a meta-analysis, which is meant to eliminate some of that bias by taking many studies (51 if I read correctly) and weighing them based on their merits and processes to look for statistical significance. Sure, it's not a perfectly executed double blind, but it's still an important study and the results shouldn't just be thrown out.

  13. Re:Maybe Willow Bark instead by mutube · · Score: 5, Informative

    Aspirin is already converted to salicylic acid (I think), so you may be better off (study this) with the natural precursor 'Willow Bark'.

    You've got this exactly backwards (unfortunately this was also about the only time you were 'exact' in your entire post).

    If I wanted to take aspirin daily, I'd take it that way instead, since it may be kinder and gentler on your system.

    So you essentially have no idea. But it being natural feels all warm and fuzzy so you will do that instead of basing your decisions off nasty pointy facts.

    You can die from other things besides cancer and heart disease...like a failed liver or thin blood.

    Or self-medicating with incorrectly dosed quanties of active drugs derived from an poorly regulated source.