How Chemistry Stymies Attempts To Regulate Synthetic Drugs
Hugh Pickens writes "Brandon Keim reports that the war on drugs has a new front, with chemists fabricating synthetic mimics of marijuana, dissociative drugs and stimulants. So far lawmakers appear to be a losing the war, as every time a new compound is banned, overseas chemists synthesize a new version tweaked just enough to evade the letter of the law in a giant game of chemical Whack-a-Mole. 'Manufacturers turn these things around so quickly. One week you'll have a product with compound X, the next week it's compound Y,' says forensic toxicologist Kevin Shanks. 'It's fascinating how fast it can occur, and it's fascinating to see the minute changes in chemical structure they'll come up with. It's similar, but it's different.'
During the last several years, the market for legal highs has exploded in North America and Europe. While people raised on Reefer Madness-style exaggerations may be wary of claims that 'legal high' drugs are dangerous, researchers say they're far more potent than the originals. Reports of psychotic episodes following synthetic drug use are common and have led to a variety of laws, but so far the bans aren't working, as the drugs can be subtly tweaked so as to possess a different, legal molecular form. One obvious alternative approach is to ban entire classes of similar compounds; however this is easier said than done. 'The problem with that is, what does "chemically similar" really mean? Change the structure in a small way — move a molecule here, move something to the other side of the molecule — and while I might think it's an analogue, another chemist might disagree,' says Shanks. 'That's the crux of the entire problem. The scientific community does not agree on what "analogue" essentially means.""
Doesn't every chemical have to go through thorough tests before deemed safe for human consumption?
All of it.
Some junkies will kill themselves... but that will taper off quickly. Some kill themselves. Some don't. Some never touch the stuff. If people want to destroy themselves... let them.
I've decided to stop wasting my time responding to AC trolls/sockpuppets... so if you want a response from me... login.
What this means is that the drugs which are legal, are potentially more dangerous than the ones which are banned. Marijuana, mushrooms, LSD have been around long enough that they've been well studied, and we know the risks are minimal. But the latest synthesised version of them has not been studied, and might be dangerous. When will we learn that the war on drugs is just making things worse?
Deconstruct the State
Let's ban synthetic drugs while the tradicional/crime financing drugs are still around
Let's make more difficult for people to have their nicotin fix in a less harmful way by banning all 'less harmful' alternatives.
The drug traffickers and tobacco companies are grateful for your cooperation.
how long until
And they say there is no innovation in America...
Make it illegal to sell drugs without declaring the exact compounds and forbid driving or operating dangerous machinery under the influence of any drug.
What about Prozac? What about caffeine, or sugar for that matter. These are all psychoactive chemicals, and quantifying the difference between them and ... say cocaine... is extremely subjective.
-=Geoskd
I wish I had a good sig, but all the good ones are copyrighted
Blacklisting is always going to be running behind the curve. I think whitelisting allowed recreational mood/thought-altering substances (currently: ethanol, nicotine, caffeine, sugar, fat, others?) might work better. Simply make it illegal to sell or distribute new substances to the general public without permission from the FDA.
One pill makes you larger, and one pill makes you small
And the ones that mother gives you, don't do anything at all.
The FDA is never going to whitelist anything potent for over-the-counter recreational use.
When our name is on the back of your car, we're behind you all the way!
Why not pass a law that just bans any drug that has the potential to be used recreation-ally? Or is that too easy?
Because that always works so well...
Humanity was getting high since the dawn of time. At some point people are going to have to confront the fact that humanity enjoys altering their consciousness for recreational purposes.
You mean like alcohol and tobacco? People use caffeine recreationally, despite the danger in doing so. There are a number of ornamental plants that can be used as a drug.
We need to go in the other direction, and stop banning drugs. We also need to stop letting a law enforcement agency dictate the laws it is charged with enforcing (see: emergency drug scheduling). While we are at it, let's stop having paramilitary police, stop attacking civil rights, and stop having the largest prison population on Earth.
Palm trees and 8
I think whitelisting allowed recreational mood/thought-altering substances
That is exactly what we have now. How does this help at all?
We should legalize drugs, and then apply truth in advertising laws to drug packaging. The FDA can evaluate the safety and risks of recreational drugs; the packages should include a summary of that assessment, and drugs which have not been assessed should have a big warning on them. Give people accurate information, not a jail cell, when they want to get high.
Palm trees and 8
Working in drug discovery, I'm still amazed at how often a small change of sometimes even a single atom of a molecule can take an pharmacologically active molecule and make it near-worthless - or even worse take a (relatively) safe molecule and turn it unacceptably toxic. I'd stay FAR away from any "analogue" being created with the sole purpose of rounding a ban without having any sort of safety and probably minimal efficacy testing.
I'd say this kind of story gives even stronger evidence for why illicit drugs (the less-toxic at least) should be legalized & controlled - if this article is not overly sensational and there really is an escalating war of chemistry we could get into some pretty nasty stuff being marketed to consumers who do not know any better.
I've got news for you. If the guy beat his adoptive mother and brother to within an inch of their lives on K2, then they should thank their lucky stars he was on K2, or they would be dead right now.*.
Disclaimer:I've actually tried K2 and know what I'm talking about.
Perhaps you were unaware of this, but when the government wants to make something illegal, they are often not truthful. Furthermore, correlation doesn't equal causation. If one smokes a joint and then goes and kills someone, they didn't kill someone because they smoked a joint; they killed someone because they are a murderous person.
Guns don't kill people; Physics kills people! - John Lithgow as Dick Solomon on Third Rock From The Sun
In Canada, the Controlled Drugs and Substances Act bans "Cannabis, its preparations, derivatives and similar synthetic preparations".
http://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-24.html#h-27
...religion hates spiritual experience and even simple pleasure it doesn't ration.
Note the level of Bible Thumper influence which not only drove Prohibition, but anti-"narcotics" (cannabis is not one) laws in the same era.
Taliban must control sex and control other pleasures, and to accomplish that goal must define disobedience as "sin" then punish it.
The cost of WOSD is spectacular, and it fuels the wave of immigration from the narco-states it creates (though the Christian Taliban are completely incapable of connecting the disruption of civil society with flight to the US!).
"This post is an artistic work of fiction and falsehood. Only a fool would take anything posted here as fact."
Caffeine is a non-selective adenosine antagonist. Prozac is an SSRI. Cocaine is an SNDRI. Sugar is indirectly psychoactive, at best. The pharmacology is far from subjective.
...religion hates spiritual experience and even simple pleasure it doesn't ration.
Thus explaining why Jews are required to drink wine every week and are required to drink four glasses (definitely enough for almost anyone to at least get a buzz) on Passover. You also forgot about the numerous religions that use psychedelic mushrooms as part of their ceremonies. Religion is not the problem here.
If you want to know why we have a war on drugs, I can think of the following more plausible explanations:
Religion is really a minor issue here. There are a few priests who will pound on their pulpits about the evils of drugs, but their power in the drug war is limited at best.
Palm trees and 8
If someone discovered a new biologically harmless but mind-altering drug, it would be made illegal, too. They are banning these things not only, or even primarily, because they are dangerous, but because they get you high.
These synthetic drugs aren't mimicking the effects of marijuana, or of LSD. They just change your perceptions or ideas. They aren't mimicking the effects of valium, either, but nobody ays that they are. Because "mimicking valium" isn't scary scary scary. Because the corporate mass media isn't trying to scare people about valium. Because valium is actualy Valium, a brand name drug sold by giant pharmacos that advertise on TV. Marijuana and LSD are sold by independent operators who don't pay TV corps $billions a year to make them sound friendly. That's why they're illegal. Even though they're not anywhere near as scary as valium, which is actually addictive.
But that doesn't stop Slashdot from saying these drugs "mimic marijuana", or the Miami cops telling the corporate mass media that bath salts are "a new form of LSD" when some idiot turns themself into a flesh eating zombie possibly by smoking some. Because there's no corporate PR pushback to protect the brand, any kind of inane lie will fly around the media if it appeals to fear of drugs.
The fact that in 2012 the mass media is quoting cops saying bath salts are "the new form of LSD", and Slashdot is pimping the idea that some arbitrary drug "mimics marijuana" shows that the only victory in the Drug War is the first casualty of any war: the truth.
--
make install -not war
How about you just leave us alone with whatever we want to do with our protein receptors?
Criminalize actual acts that actually harm someone else, regardless of the cause. If you want to make an aggravated crime out of doing harm as a result of doing something else that's known to be risky, especially on a second or further conviction, that's got some merit.
But criminalizing people self-stimulating (or inhibiting) their own bodies is tyranny. It has failed over and again, every time, creating far more damage than the drug consumption ever has. While failing to stop the consumption. And destroying both justice itself and the people's ability to trust it, atop the rubble of everything else the prohibition touches.
--
make install -not war
while I might think it's an analogue, another chemist might disagree,' says Shanks. 'That's the crux of the entire problem.
The author seems to have missed the fact that the real crux of the problem and that is that the country has banned the relatively safe versions, causing people to seek out these dangerous copies.
The world has changed in the last twenty years. Online control by voter polling of our representatives' legislative acts has become a technical possibility. We can now go beyond the village and state level. We could set up a system whereby everybody would only need access to the Internet to securely vote.
No matter how many laws or constitutional changes we manage to have enacted, none would have such political impact as simply enacting an amendment allowing voters to repeal unwanted legislation.
Do you really want to have open heart surgery under a local?
Perhaps you'd like to be the one to explain to chronic pain sufferers that they're just going to have to suffer living hell because otherwise someone might do something stupid (or have some illicit fun)?
What about things that are 'not a drug' like paint thinner, GHB or bath salts?
1. Legalize marijuana and traditional hard drugs: cocaine, methamphetamine and amphetamine, heroin, morphine, ketamine, MDMA, etc. I have reservations about PCP, but heck, legalize it too--because my system will create strong but non-criminal incentives to not sell people PCP (which is one of the very few drugs that can actually cause drug psychosis--meth's propensity for this is WAY over hyped by propaganda, and more likely due to poor nutrition and impure drug anyway in the rare cases that it occurs. Now do this:
2. Do NOT regulate and tax the heck out of it. Just:
2a. Pharmacy is legally exempt from legal ramifications if buyer has an adverse reaction.
2b. Pharmacy is legally restricted to sell a modest "ration" to each buyer per week. Of course, addicts will try to get their friends to sell them their ration. This is OK. Remember--it's all legal. But...
3. Since ONLY a pharmacist is legally exempt from lawsuit for selling the regulated amount, and your friend or factory is NOT, your friend can choose to sell it to you or not. But many, such as myself, will tell you to go away because I have a life and a job, etc., and am not interested in the risk of a lawsuit because you blow your heart out snorting my weekly 0.5g of coke, for a measly $20. Some people will choose to take the risk and peddle their rations. That's Ok--but the incentive will be to not do this.
4. A free market for medical insurance to create financial incentives to not abuse drugs. The market may then evolve the following situation:
4a. Disaster insurance--covers hospital stays and serious medical bills that would financially wreck the typical person. Cheap to buy, but relatively high deductibles of several $1000. That will make most healthy young adults happy. Buy preventative care and small incidental care with cash--it will be much cheaper without the gov. mandating that doctors and ins. cos. cover everything. It cost me $7 for a doctor visit when I was a kid.
4b. More thorough insurance that covers stuff like child delivery, some prescription meds., etc. More expensive, but lower deductible, and guaranteed to cover things that are likely but not certain to happen, like child birth. Suitable for middle class folks when they get started on their careers.
4c. Steep discounts for healthy lifestyles. You take cocaine and heroin and it shows on your yearly insurance co. piss test, that's Ok. You just don't get the healthy lifestyle discount. Strong incentive for folks to not abuse drugs. Occasional users can just not use any for 2 weeks before their piss test.
4d. Charity hospitals for caring for the poor. To the extent that the charity system has the resources to treat. This was what worked, imperfectly, but better than bankrupting a whole nation which is going to happen with the present system. Then we will all get nothing. And how big a health risk is a civil war?
4e. Government clinics for preventative care, first aid, shooing away people with the common cold, vaccines, urgent care etc. I'm a libertarian, but life isn't simple. I'll make a compromise here. But no, we will NOT treat you with $500000 of care to extend your life 6 months when you are 77 and at the end of the road. We'll give you a bottle of morphine if you can't afford it and send you on your way to meet you maker. It's what we all much ultimately face. My neighbor should not be obligated to pay for my life extension with 1/2 of his lifetime earnings.
5. Pharmaceutical drugs should be similarly deregulated, so that folks with terminal diseases who are going to die anyway can take the risk of testing a new drug that has little risk data behind it, but which might just save them. And nonsense like this doesn't happen anymore... A final little anecdote:
GHB (gamma-hydroxy butyric acid) was banned because a handful of people were victimized by the "date rape" crime. One could argue that they took a large risk by hanging out with the nightclub trash where this happens anyway. Anyway, it u