X Chromosome May Leave a Mark On Male Fertility
sciencehabit writes "Behind every great man, the saying goes, there's a great woman. And behind every sperm, there may be an X chromosome gene. In humans, the Y chromosome makes men, men, or so researchers have thought: It contains genes that are responsible for sex determination, male development, and male fertility. But now a team has discovered that X—'the female chromosome'—could also play a significant role in maleness. It contains scores of genes that are active only in tissue destined to become sperm. The finding shakes up our ideas about how sex chromosomes influence gender and also suggests that at least some parts of the X chromosome are playing an unexpectedly dynamic role in evolution."
The neo-feminists will not stand for it! This has to be another male-dominated science propaganda finding and must be a lie!
Most ACs are not even worth the keystrokes to insult them. Be generically insulted by this and ignored otherwise.
...women! Excellent news for crossdressers. Bad news for religious fundamentalists of the middle east *wink* *wink*.
This is what happens when you have 3.5 Billion years of hacks. Legacy code, no overall architecture and absolute chaos.
Let's start over and redesign humans from the ground up.
And where's the documentation?
If the X genes were the same as mice, then all the girls would not be human. And some HAVE to be active during the creation of sperm - after all, half the sperm have an X, the other half have the Y.
The y chromosome doesn't code many genes at all, and this has been known for a long time. It's main function is turning specific genes off. Anatomy of all sorts, including gender characteristics is coded across all 24 chromosomes. The y just suppresses the female parts.
If I learn something over a decade ago in a high school class, it shouldn't be "science news."
The Y chromosome is a li'l runt and they think it won't even be there anymore in a hunnert thousand years or so.
Somet7hing cool national gay Nigger
Behind every great man, the saying goes, there's a great woman
Behing every failed man, there is a failed woman.
Slashdot social media options: AIM, ICQ, Yahoo, Jabber and Mobile Text. Why no MySpace?
Science still have a long way to go in decoding natures mysteries. It wasn't that long ago that it was reported that the Y chromosome used ECC, compression, and was encrypted with AES.
the Y chromosome makes men, men,...
We all know that Football - American Football - and Rugby make men. So do guns and Water Polo ( Water Polo makes Rugby players look like the fags they are. LaCross?! - Rich boy homos!) .
The more guns you have, the more man you are.
I mean really, the biologists need to examine how many gun toting Water Polo players there are.
Fucking Homos!
I thought this was implied when it was determined that the Y chromosome is a mutated X chromosome. The same reason dudes have nipples, yeah?
th3 system clean
The y just suppresses the female parts.
So the suppression of females by the Y Chromosome is natural, and this is what evolution has intended and achieved, and the general oppression of the women in the society is just a natural extension of what is going on in cellular level. So all the male chauvinistic pigs can now breath a sigh of relief, "we can't help it. we are born this way".
sed -e 's/Chuck Norris/Rajnikant/g' joke > fact
Actually, it does both: Turn genes on, and turn genes off.
Take for instance, "TDF Males".
(TDF == Testis Determining Factor, and is encoded by the SRY gene on the Y chromosome)
This single gene is sometimes translocated to the X chromosome in a rare mishap of cellular meiosis during gamete production.
http://en.wikipedia.org/wiki/XX_male_syndrome
Since this is just a single gene out of the many on the Y chromosome, resulting phenotypical male offspring are infertile, and the "androgenization" of the offspring is incomplete, often showing signs of feminine features.
The Y chromosome contains more than just SRY, and does quite a bit more. Specifically, it contains genes for sperm specific cellular features, like the AZF1 gene,
(https://en.wikipedia.org/wiki/AZF1 ), without which you can't produce sperm cells.
Given the limited real-estate of the Y chromosome, and it's structural fragility (See the "shrinking Y chromosome" theory, https://en.wikipedia.org/wiki/Y_chromosome#Shrinking_theory ), it makes LOADS of evolutionary sense to offload as much vital genetic data off of it as possible, and onto more stably recombining chromosomes as is possible.
The real thing here, is that "most of being male, is present in the female genotype". Most, but not all.
Otherwise there would be very little genetic diversity between father and
son regarding fertility, and we know that to be false.
"...the Y chromosome makes men, men, or so researchers have thought..."
Two of my choices are the same thing, and the third is a short phrase. Interesting.
I guess I always assumed that the Y determined sex, not that everything about maleness was encoded on it --- a signal rather than a guidebook.
Which species has 24 chromosomes?
The y chromosome doesn't code many genes at all, and this has been known for a long time. It's main function is turning specific genes off. Anatomy of all sorts, including gender characteristics is coded across all 24 chromosomes. The y just suppresses the female parts. If I learn something over a decade ago in a high school class, it shouldn't be "science news."
Yeah, it's very poorly written. The news here is that there are far more genes active only in males on the X chromosome than expected. This is important when studying how evolution happens. The science writer largely misses this exciting result focuses, as you say, on something that's been known for decades.
The previous science article about accurately measuring sea level in the past has the same stupidity when written up by others.
The human species has:
1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,X, and Y.
How many do you count?
The Y chromosome contains more than just SRY, and does quite a bit more.
SRSLY?
Women, X-X. Men, X-Y. Chuck Norris, Y-Y.
There is no chick in Chuck Norris.
It just means men are females that have been suppressed. We're the victims here!
The Y chromosome is a li'l runt and they think it won't even be there anymore in a hunnert thousand years or so.
I don't think there's anyone who takes this seriously any more. There were some people suggesting that if genes are lost at a linear rate off the Y chromosome, it should disappear in another 10 million years. However, chimpanzees and humans show no difference in the number of genes on the Y chromosome since we diverged 6-7 million years ago, and we've both only lost one gene since we diverged from the rhesus macaque 25 mya. Given that sequencing of the platypus genome puts the common mammalian Y chromosome at a max of age of 166 mya, this suggests the linear model is just wrong.
The Wikipedia has good article on this from which I drew my numbers, if you're interested in more.
If it's for-profit but free, you're not the customer -- you're the product (e.g., the Slashdot Beta's "audience").
Can't live with em, can't live without em.
Yes. Exactly. Exactly. Exactly.
The Y chromosome has degenerated because it is only present in males. Therefore it does not benefit from crossover. Therefore a bad mutation on it is passed down to all generations of males from that point on. This makes it a very poor place to put useful genes, and it is gradually becoming nothing more than a device to determine gender.
Look, I didn't name it that ok?
Want a truly silly name? Look up "sonic hedgehog gene".
For realz.
That the basic body plan is female to start with. I mean why else would men have nipples too?
And look at differences in the reproductive organs of men and women. Testes and Ovaries - just small deviations create each, and of course location.
This is nothing new. The Y-Chromosome is too small to actually code for anything, and no one ever thought that it could contain more than a handful of genes. The Y is just a set of GOTOs pointing to the X.
Oppression of women is as natural and greed and cruelty, and just as avoidable.
I wish I could vote up on this account. This is such a fascinating topic.
And behind every great woman, there's a man. Staring at her ass.
Actually not, but he did write this pun filled song - to the tune of "Home on the Range,"
Oh, give me a clone
Of my own flesh and bone
With its Y-chromosome changed to X
And when it is grown
Then my own little clone
Will be of the opposite sex.
More if you search for it.
If you look at all the chromosomes though, there are a lot of "runts". The size of the chromosome doesn't matter as long as they can hold a few genes that are vital.
To be honest, I did check EntrezGene first to see whether there really is a SRSLY gene. Apparently not; all I got was SRSY, a little-boy-mouse gene.
It is "X Window System". "WindowS" is a trademark of Evil Redmond, Inc,
Those first 22 are pairs. Humans have 46 chromosomes, two of which are the X and Y.