Slashdot Mirror


Sleep Is the Ultimate Brainwasher

sciencehabit writes "Every night since humans first evolved, we have made what might be considered a baffling, dangerous mistake. Despite the once-prevalent threat of being eaten by predators, and the loss of valuable time for gathering food, accumulating wealth, or having sex, we go to sleep. Scientists have long speculated and argued about why we devote roughly a third of our lives to sleep, but with little concrete data to support any particular theory. Now, new evidence (abstract, full text paywalled) has refreshed a long-held hypothesis: During sleep, the brain cleans itself." During sleep, the Cerebrospinal fluid fills channels in the brain, collecting waste products. It uses a lot of energy, leading to the hypothesis that the brain can't clean up waste while also processing sensory input.

19 of 210 comments (clear)

  1. Extremely variable sleeping periods by DavidHumus · · Score: 4, Interesting

    I wonder how well this accounts for the extremely variable sleeping periods of various animals? See http://faculty.washington.edu/chudler/chasleep.html .

    1. Re:Extremely variable sleeping periods by Anonymous Coward · · Score: 5, Funny

      Cats must have very clean brains!?

    2. Re:Extremely variable sleeping periods by acariquara · · Score: 4, Informative

      Humans are polyphasic too, as infants. We are conditioned into a 8-hour cycle, but it's neither the most efficient nor the best one for your health.

      --
      Dear aunt, let's set so double the killer delete select all
    3. Re:Extremely variable sleeping periods by turkeydance · · Score: 5, Funny

      yep...brain waste excreted with hair balls.

    4. Re:Extremely variable sleeping periods by Samantha+Wright · · Score: 5, Informative

      Here's the other link you want; that article only details artificial patterns. In short: it's normal to wake up briefly in the middle of the night, and take about 9-10 hours from when you first go to bed till when you last wake up.

      --
      Bio questions? Ask me to start a Q&A journal. Computer analogies available for most topics!
    5. Re:Extremely variable sleeping periods by war4peace · · Score: 5, Funny

      "This was also a favorite time for scholars and poets to write uninterrupted, whereas still others visited neighbors, had sex, or engaged in petty crime." ...Or all the above, at the same time :)
      Like visiting a neighbor to have sex with his wife and steal some silver in the process... and then write about it.

      --
      ...gis sdrawkcab (usually not responding to ACs; don't bother posting as AC)
    6. Re:Extremely variable sleeping periods by mspohr · · Score: 4, Interesting

      When I was in medical school, I adopted a pattern of going to sleep for 4 hours in the early evening, waking up at midnight and studying for 4 hours then back to sleep for a few hours. This seemed to work well and improved my grades.

      --
      I don't read your sig. Why are you reading mine?
    7. Re:Extremely variable sleeping periods by ignavus · · Score: 4, Interesting

      Cats must have very clean brains!?

      It's hard work running the world and performing the duties of an Egyptian god.

      Every cat knows that the human race is merely there to serve them and that's a huge responsibility.

      And then there's scripting all those funny cat videos just to keep us humans (their pets) amused.

      No wonder cats are tired out most of the time.

      --
      I am anarch of all I survey.
    8. Re:Extremely variable sleeping periods by ozmanjusri · · Score: 4, Funny

      Hi, ho Silver...

      --
      "I've got more toys than Teruhisa Kitahara."
  2. Like so many computer programs... by christianT · · Score: 5, Funny

    Humans suffer from major memory leaks and must be shut down periodically due to poor garbage collection.

    1. Re: Like so many computer programs... by TheReaperD · · Score: 4, Interesting

      A few rare people can achieve a REM-like state while awake. I am one of them. In my case, I learned to do it due to having a lifelong hereditary sleep disorder. Going without sleep for up to five days is a common occurrence. I enter a trance state and begin to dream. I have more control over these dreams than during normal sleep but, I am mostly unaware of my environment though it is not hard to snap me out of it. I'm aware enough that if my name is called or someone touches me, I come out of it. On rare occasions, the dream state does not end right away and I have both stimuli at the same time. It is awkward but, navigateable. The state give me most of but, not all of the benefits of real sleep. My mind responds as if rested, it stops dulusions that occur because of sleep loss and the general mental slowdown that naturally occurs. What it doesn't do is some of the more complex physical cleaning that the body does when you sleep such as clearing substance P from your pain receptors. As I have fibromyalgia, this last point is very relevant.

      --
      "Be particularly skeptical when presented with evidence confirming what you already believe." -
  3. Re:Obvious question by interkin3tic · · Score: 5, Interesting
    From TFA:

    Many neurological diseases—from Alzheimer's disease to stroke and dementia—are associated with sleep disturbances, Nedergaard notes. The study suggests that lack of sleep could have a causal role, by allowing the byproducts to build up and cause brain damage. "This could open a lot of debate for shift workers, who work during the nighttime,” Nedergaard predicts. "You probably develop damage if you don’t get your sleep."

    Beta amyloids are specifically mentioned, those make up the plaques that are found in Alzheimers.

    Worth pointing out that the effects of sleep deprivation are well known, this is simply trying to explain HOW those symptoms occur.

  4. Re:Obvious question by Anonymous Coward · · Score: 5, Funny

    Apparently, brain poop which may lead to many brain farts.

  5. Re:Obvious question by Deflagro · · Score: 4, Interesting

    I went almost a week without sleep and it definitely screws you up. On day 5, I was hallucinating that there were people around me and seeing things out of the corner of my eye. I had a constant fuzzy feeling and had very little energy. It was an interesting experiment and it was not easy to get to sleep. It took me over a month to get back into a proper rhythm.

    --
    Der Tod ist der einzige Weg hier raus!
  6. Re:Neat. by SJHillman · · Score: 4, Funny

    For teenagers, it's more like a cron job running rm -rf /knowledge/school/exam_answers/*

  7. Re:Couldn't you come up... by GrandCow · · Score: 4, Informative

    ...with a better word than "brainwashing?" Since that already means something that does not match the contents of the article.

    BEEP BOOP I am a robot can't detect a joke.

    Brainwashing is a perfect word to use here since that's exactly what's happening.

    --
    "Well kids, you tried your best, and you failed. The lesson is, never try." -Homer Simpson
  8. Re:Couldn't you come up... by jamesh · · Score: 4, Funny

    ...with a better word than "brainwashing?" Since that already means something that does not match the contents of the article.

    Agree. A "dirty mind" joke would have gone down far better.

  9. Re:Obvious question by interkin3tic · · Score: 4, Interesting

    I agree that it doesn't seem like night or day would matter much.

    The second point, you're responding to a new hypothesis put forth by the researcher based on the current findings. The current findings are only that it's cleared out during sleep, not saying that low neural activity is the reason. That part is just speculation. I'd suggest it's probably more complex, that the glial cleaning activity causes abnormal neuronal activity when it's in that mode. Perhaps the reason it happens during sleep is because if it happened while you were awake, you'd hallucinate, act even more irrationally and irregularly etc. Perhaps that's part of the reason that dreams are so bizarre. Pure speculation.

  10. In short, you're killing yourself. by Valdrax · · Score: 5, Informative

    You're possibly setting yourself up for Alzheimer's. It's been known for a long time that buildup of amyloid plaques is worsened by lack of sleep and vice versa. (Sleep issues show up long before other symptoms of Alzheimer's). This provide a mechanism by showing how the plaques are regularly removed by good sleep.

    For extra fun, sleep is also when myelin-repairing oligodendrocytes kick into gear. You probably won't develop MS from not sleeping, but it isn't good for your long-term health, as that function is necessary to the survival of brain cells. This impacts mood, memory, and moral judgement.

    Oh, and then there's the fact that lack of sleep disrupts the ratio of leptin and ghrelin in your body, making you far hungrier when awake. This is part of the reason that lack of sleep is correlated with obesity. You also have lower testosterone (impacting your virility) & higher cortisol levels (wrecking your memory and weakening your immune system). Other hormone changes put you at higher risks of type 2 diabetes.

    In short, you're killing yourself. Seek help if this isn't voluntary. Prioritize getting more sleep.

    --
    If it's for-profit but free, you're not the customer -- you're the product (e.g., the Slashdot Beta's "audience").