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Sleep Is the Ultimate Brainwasher

sciencehabit writes "Every night since humans first evolved, we have made what might be considered a baffling, dangerous mistake. Despite the once-prevalent threat of being eaten by predators, and the loss of valuable time for gathering food, accumulating wealth, or having sex, we go to sleep. Scientists have long speculated and argued about why we devote roughly a third of our lives to sleep, but with little concrete data to support any particular theory. Now, new evidence (abstract, full text paywalled) has refreshed a long-held hypothesis: During sleep, the brain cleans itself." During sleep, the Cerebrospinal fluid fills channels in the brain, collecting waste products. It uses a lot of energy, leading to the hypothesis that the brain can't clean up waste while also processing sensory input.

8 of 210 comments (clear)

  1. Like so many computer programs... by christianT · · Score: 5, Funny

    Humans suffer from major memory leaks and must be shut down periodically due to poor garbage collection.

  2. Re:Extremely variable sleeping periods by Anonymous Coward · · Score: 5, Funny

    Cats must have very clean brains!?

  3. Re:Obvious question by interkin3tic · · Score: 5, Interesting
    From TFA:

    Many neurological diseases—from Alzheimer's disease to stroke and dementia—are associated with sleep disturbances, Nedergaard notes. The study suggests that lack of sleep could have a causal role, by allowing the byproducts to build up and cause brain damage. "This could open a lot of debate for shift workers, who work during the nighttime,” Nedergaard predicts. "You probably develop damage if you don’t get your sleep."

    Beta amyloids are specifically mentioned, those make up the plaques that are found in Alzheimers.

    Worth pointing out that the effects of sleep deprivation are well known, this is simply trying to explain HOW those symptoms occur.

  4. Re:Obvious question by Anonymous Coward · · Score: 5, Funny

    Apparently, brain poop which may lead to many brain farts.

  5. Re:Extremely variable sleeping periods by turkeydance · · Score: 5, Funny

    yep...brain waste excreted with hair balls.

  6. Re:Extremely variable sleeping periods by Samantha+Wright · · Score: 5, Informative

    Here's the other link you want; that article only details artificial patterns. In short: it's normal to wake up briefly in the middle of the night, and take about 9-10 hours from when you first go to bed till when you last wake up.

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  7. Re:Extremely variable sleeping periods by war4peace · · Score: 5, Funny

    "This was also a favorite time for scholars and poets to write uninterrupted, whereas still others visited neighbors, had sex, or engaged in petty crime." ...Or all the above, at the same time :)
    Like visiting a neighbor to have sex with his wife and steal some silver in the process... and then write about it.

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  8. In short, you're killing yourself. by Valdrax · · Score: 5, Informative

    You're possibly setting yourself up for Alzheimer's. It's been known for a long time that buildup of amyloid plaques is worsened by lack of sleep and vice versa. (Sleep issues show up long before other symptoms of Alzheimer's). This provide a mechanism by showing how the plaques are regularly removed by good sleep.

    For extra fun, sleep is also when myelin-repairing oligodendrocytes kick into gear. You probably won't develop MS from not sleeping, but it isn't good for your long-term health, as that function is necessary to the survival of brain cells. This impacts mood, memory, and moral judgement.

    Oh, and then there's the fact that lack of sleep disrupts the ratio of leptin and ghrelin in your body, making you far hungrier when awake. This is part of the reason that lack of sleep is correlated with obesity. You also have lower testosterone (impacting your virility) & higher cortisol levels (wrecking your memory and weakening your immune system). Other hormone changes put you at higher risks of type 2 diabetes.

    In short, you're killing yourself. Seek help if this isn't voluntary. Prioritize getting more sleep.

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