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Schizophrenia Is Not a Single Disease

An anonymous reader writes: New research from Washington University has found that the condition known as schizophrenia is not just a single disease, but instead a collection of eight different disorders. For years, researchers struggled to understand the genetic basis of schizophrenia. This new method was able to isolate and identify the different conditions (each with its own symptoms) currently classified under the same heading (abstract, full text). "In some patients with hallucinations or delusions, for example, the researchers matched distinct genetic features to patients' symptoms, demonstrating that specific genetic variations interacted to create a 95 percent certainty of schizophrenia. In another group, they found that disorganized speech and behavior were specifically associated with a set of DNA variations that carried a 100 percent risk of schizophrenia." According to one of the study's authors, "By identifying groups of genetic variations and matching them to symptoms in individual patients, it soon may be possible to target treatments to specific pathways that cause problems."

222 comments

  1. Then I guess you could say... by toonces33 · · Score: 4, Funny

    that schizophrenia itself has a bit of a split personality.

    1. Re: Then I guess you could say... by Anonymous Coward · · Score: 5, Informative

      You could also be referring to "multiple personalities," which is also known as Dissociative Identity Disorder. Neither Bipolar nor DID are the same as Schizophrenia.

    2. Re: Then I guess you could say... by sg_oneill · · Score: 4, Informative

      *rimshot*. I do realise your just making a joke, however it is worth noting that multiple personalities is not considered part of the schizophrenia spectrum, but rather part of the disasociative disorders spectrum. Its a ketamine disease rather than an Acid disease, to make a metaphor.

      --
      Excuse the Unicode crap in my posts. That's an apostrophe, and slashdot is busted.
    3. Re: Then I guess you could say... by linuxrocks123 · · Score: 4, Interesting

      No, he's thinking of multiple personality disorder, which is extremely rare and much different than schizophrenia. It's confused with schizophrenia because of the hallucinatory voices common in schizophrenia, but those "voices" aren't different personalities of the afflicted; they're just hallucinations. Multiple personality disorder is the split personality one -- the person is basically like Dr. Jekyll & Mr. Hyde, although the personalities don't have to be good/evil or working at cross purposes to each other, and there can be more than two.

      --
      vi ~/.emacs # I'm probably going to Hell for this.
    4. Re:Then I guess you could say... by Anonymous Coward · · Score: 5, Informative

      I'm schizophrenic with mild hallucinations but I hear shit around the clock and it gets extremely annoying. I know it's not real, but there are days where I'm like leave me the fuck alone. I'd be cool with it if it were Ed Harris but everything I hear is abstract so I keep it pretty loud in my room to drown it out. Luckily my case is not too bad, but it's bad enough that I can imagine what people with serious cases go through. I feel extremely bad for people that have been drove out of their minds.

      The feeling of knowing what you're seeing or hearing is fake is indescribable.

    5. Re:Then I guess you could say... by Quantum+Apostrophe · · Score: 1

      Sounds terrible. Is there no way to stop this shit? Medication? Electroshock? Cutting out the bad wiring?

    6. Re:Then I guess you could say... by Miamicanes · · Score: 3, Interesting

      I've always wondered whether someone experiencing audio hallucinations they couldn't distinguish from real sounds could use software as a prosthetic. Say, write a program to continuously sample sound, display the past 5 minutes or so of waveform history on-screen, do realtime speech recognition, and annotate the waveform display with a transcript of what it thought it heard... so if they thought they heard something really disturbing, they could look at the display to see whether there was an organized waveform a few moments earlier, and listen to it again if they wanted to be sure..

      If someone with schizophrenia did that, would it help? Or would it stimulate the development of new neural pathways & eventually make matters worse by inducing visual hallucinations on top of the auditory ones in an attempt to bring their physical perception of reality in line with their mental one?

    7. Re:Then I guess you could say... by TheRealQuestor · · Score: 1

      The feeling of knowing what you're seeing or hearing is fake is indescribable.

      Odd I seem to remember, in my youth, that acid was pretty much that to a T and I can describe it as pretty awesome.
      That said I KNEW why it was happening and I am sure that is much different that having it happen for no good reason :(

    8. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      You can test for it in the amniotic fluid, then take care of it with an abortion.

    9. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      YEEAAAAHHHHH

    10. Re:Then I guess you could say... by Anonymous Coward · · Score: 4, Interesting

      That would likely help. For those that don't know if the hallucinations are real. However, the problem with hallucinations is that they'll drive you nuts even if you know they're not real. I remember the hallucinations would get so loud that I'd yell at them even though I knew they weren't real because I could barely hear anything else.

      The trick is that doctors need to stop treating schizophrenics like we're sick. They need to start treating us like we're real people that just happen to have a different sense of reality. Trying to force us to buy into a reality that's every bit as fake as the one they're trying to get us to give up is ludicrous. It's not curable per se, but if we're given the tools to evaluate things for ourselves, the brain will eventually rewire itself in a way that's more functional.

      Ultimately, people need to accept the symptoms as symptoms. Trying to fight the disorder is a losing battle. Eventually I got to the point where I missed the voices and started to intentionally cause the hallucinations. Before too long I was having trouble maintaining them and that aspect of the disorder was more or less gone.

      The rest is really psycho-social education. It's not that schizophrenics can't be treated or virtually cured, it's that the mental health establishment makes more money with ineffectual treatments than it does for treatments that would improve the situation. There's some very good work being done in the neurosciences that could make a huge difference. Unfortunately, it would put psychologists completely out of business as it requires work from psychiatrists and therapists, but not psychologists.

    11. Re: Then I guess you could say... by Anonymous Coward · · Score: 0

      Roses are red
      Violets are blue
      I'm schizophrenic
      and so am I!

    12. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      I'd be horrified by this. My brother is a schizophrenic and my life, and I daresay the world, would be seriously worse without his love and creativity. He is a beautiful person, very generous to his friends and the community he lives in (many with mental health issues), and a great musician.

    13. Re:Then I guess you could say... by Guy+Harris · · Score: 1

      I'd be cool with it if it were Ed Harris

      If you're referring to Pollock, hee came across in the movie as being manic-depressive, not schizophrenic.

    14. Re:Then I guess you could say... by theshowmecanuck · · Score: 2

      And it has an expected end when things go back to normal.

      --
      -- I ignore anonymous replies to my comments and postings.
    15. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      A Beautiful Mind, I'm guessing.

    16. Re: Then I guess you could say... by Anonymous Coward · · Score: 0

      but how could you trust that you weren't hallucinating the output?

    17. Re:Then I guess you could say... by Vellmont · · Score: 4, Insightful


      The trick is that doctors need to stop treating schizophrenics like we're sick. They need to start treating us like we're real people that just happen to have a different sense of reality.

      In a sense, I sort of agree with you, in another, totally not. Depression is also another way of viewing reality. Is someone who's depressed "wrong" about concentrating on the negative aspects of living? No... but I think most people who're depressed would rather NOT be depressed. Obviously telling someone who's depressed to just "cheer up", and "things aren't that bad" isn't going to help much. But like a disease, it's an aspect of yourself you'd rather not have and aren't in total control of, and want to be "cured" of. So the disease model isn't too far from the truth. I don't see how scizophrenia is much different.

      You yourself don't really like your symptoms, wouldn't you rather they be gone? So I'm not sure I really understand your point.

      --
      AccountKiller
    18. Re:Then I guess you could say... by DigitalHammer · · Score: 2

      There is an ongoing study that involves having patients yell at computer generated avatars to get the source of their hallucinations to STFU. Perhaps it may interest you: http://www.vice.com/en_ca/read...

    19. Re: Then I guess you could say... by MobSwatter · · Score: 1

      It's actually not really a comical thing, they like to blame physiology. For the most part it is the pressure applied by society simply because the numbers are not consistent with the growth of it.

    20. Re:Then I guess you could say... by sound+vision · · Score: 4, Interesting

      From the people I've known with schizophrenia (three diagnosed, a couple others probably undiagnosed) the audio hallucinations can either be recognized as hallucinations, or accepted as real, depending on the severity of the disorder at the time. If they are in a less severe mode they usually recognize the voices are not real (not to imply they can stop or control them). The recorder would do no good there. In more severe conditions, they may be unable to tell the difference between the hallucinations and reality, and the hallucinations can be not just auditory but also visual and (most importantly) cognitive. With cognitive delusions, reasoning capacity goes out the window - any kind of "evidence" presented to them would be disregarded. In the really bad cases, when they are ducking out of view of windows so the snipers outside can't get a clear shot, you won't be able to get them to look at any computer program really.

    21. Re:Then I guess you could say... by eulernet · · Score: 1

      The feeling of knowing what you're seeing or hearing is fake is indescribable.

      You make it sounds like it's a problem.
      Personally, I'm a meditator, and I *know* that everything is fake and I accept this as a fact, so I concentrate on my perception of the "reality".

    22. Re: Then I guess you could say... by Anonymous Coward · · Score: 0

      Schizophrenia is not the metal disorder associated with "split personalities." You are thinking of bipolar disorder. Funny, though...

      There's as problem with this statement. Yoiu simply don't know what "schizophrenia", "split personalities" and so on are. The psychologists / psychyatrists have been measuring and grouping things together kind of arbitrarily because they look the same. Nothing wrong with that, since that was all they had up to now. Looking at these things as genetic disorders will completely restructure their entire field in the same way that genetic grouping of animals showed that almost identical creatures were in fact completely different groups with just parallel evolution making them look similar.

      Maybe "split personalities" will turn out to just be another side of one of the diseases which is currently grouped under the "schizophrenia" disorder.

      Is there anyone here even competent to comment on genetic psychiatric medicine? It would be really interesting to hear some guesses where this is going to go.

    23. Re:Then I guess you could say... by gtall · · Score: 1

      That works for more than hallucinations, I can assure it. I find it quite effective for many of life's little frustrations.

    24. Re:Then I guess you could say... by kimvette · · Score: 1

      > that schizophrenia itself has a bit of a split personality.

      Wrong.

      Schizophrenia is when you hear "god" telling you to kill that actress.

      DID is when at times you really believe you are god, then a moment later you believe you're a receptionist at a law firm, then you believe you're a construction worker - and your personalities may or may not know one another and be friends. It's a really messed up condition - I had a friend with DID once and it was unnerving because I'd wonder who I would be talking to next time I'd see her. More recently I've encountered someone I've been chatting online with who at times insists she is Hathor, the ancient Egyptian goddess, and other times insists she is a different "god" and other times she is just her. Now, she could just be trolling people online but I really do think she genuinely has DID. It's a very strange condition.

      --
      The Christian Right is Neither (Christian nor right). See: Matthew 23, Matthew 25, Ezekiel 16:48-50
    25. Re:Then I guess you could say... by JimSadler · · Score: 2

      Thank God those of us who are not afflicted do not know what it is like to be overwhelmed with voices and visions. It has to be painful beyond understanding. The social losses also must be awful. And with this now found to be eight different diseases I wonder what effect the medications applied must have been having as the chances of getting the right meds for a particular disease must be really lousy. I fear that this new understanding may cause a lot of patients to cease taking there medications. On the up side just maybe we have reached a starting point for a real cure for this plague that has ruined millions of lives. And I hope the lawyers take notice as the discrimination by insurance companies against what is now considered an organic disease must have been illegal all along.

    26. Re:Then I guess you could say... by JimSadler · · Score: 1

      In some mental patients the amount of internal dialogue is so great that the capacity to respond to situations goes right out the window. Thinking about all the things caused by the illness in a frantic, high speed mode, disallows focusing energy into confronting the world and it just gets more and more tragic. You can see this in people who flee from the police at high speeds. Many of those folks would get a warning or a trivial ticket but they over react due to their internal dialogues and endanger themselves and everyone else in a frantic effort to escape for no reason at all.

    27. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      It could help. Unfortunately, it calls for a schizophrenic to rely on that equipment. Depending on the type of schizophrenia, a person may unable to utilize that equipment. They might not trust it. They might struggle to understand how to handle the device, etc. I live with a schizophrenic who has symptoms from multiple types with a heavy emphasis on paranoid and disorganized. This person has very low patience, high suspicion, high aggression, and struggles to varying degrees to concentrate on activities other than listening to and talking to "the voices."

      It's still a marvelous idea though. In my situation, it just wouldn't work. The schizophrenic in my case has a high amount of trust in his own thinking, and so trusts that the voices he hears are real completely.

    28. Re:Then I guess you could say... by Chris+Mattern · · Score: 1

      More importantly, not only did you know why it was happening, whether or not it happened was *your choice*.

    29. Re:Then I guess you could say... by jafiwam · · Score: 1

      The trick is that doctors need to stop treating schizophrenics like we're sick. They need to start treating us like we're real people that just happen to have a different sense of reality. In a sense, I sort of agree with you, in another, totally not. Depression is also another way of viewing reality. Is someone who's depressed "wrong" about concentrating on the negative aspects of living? No... but I think most people who're depressed would rather NOT be depressed. Obviously telling someone who's depressed to just "cheer up", and "things aren't that bad" isn't going to help much. But like a disease, it's an aspect of yourself you'd rather not have and aren't in total control of, and want to be "cured" of. So the disease model isn't too far from the truth. I don't see how scizophrenia is much different.

      You yourself don't really like your symptoms, wouldn't you rather they be gone? So I'm not sure I really understand your point.

      I have met (and married) people who "didn't feel normal" when they weren't depressed and would have constant lapses in treatment drugs (even if they worked, which most didn't).

      While they didn't enjoy being depressed, they enjoyed "not being themselves" less, or were so screwed up the cause-effect understanding was broken.

      Depression while also a complicated and layered description containing many different states, is not similar in that people always want to not be it.

    30. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      Too bad we can't test for uncaring jerks like you and then take care of it with an abortion.

    31. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      Being along I've half a mind to ask who farted but they already know who I am what I want.

    32. Re:Then I guess you could say... by tehcyder · · Score: 1

      The trick is that doctors need to stop treating schizophrenics like we're sick...It's not that schizophrenics can't be treated or virtually cured

      Your two statements contradict each other.

      --
      To have a right to do a thing is not at all the same as to be right in doing it
    33. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      Yes, you great defender of truth, pick apart the schizophrenic's post for disorganized thinking. Did your mother have any fucking children that lived?

    34. Re: Then I guess you could say... by TheCarp · · Score: 1

      and its worth noting that this means the basis for the joke is actually the same as the basis for the article, that its actually hard to tell disorders apart from an outside view. Its almost a second joke layered on top.

      --
      "I opened my eyes, and everything went dark again"
    35. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      The point here is that if you treat patients like their sick, that tends to trigger a response from the amygdala as well as causing the brain to fixate on a point that's undesirable to be at. The consequence is that you wind up with more of the behavior that you don't want and less of the behavior that you do want. As well as a patient that's less able to make changes as most of their upper brain functions are being shorted on energy necessary to function properly.

      The problem with chronic conditions is that it can very easily become a part of a person's identity. Or more to the point, a person can become so invested in their life with a disorder that they can't imagine what things would be like if it were to go away.

      You're also neglecting the fact that a person's behaviors and thoughts when they have a condition like this are usually the only rational response to the disorder. Trying to take that away leaves people in a state where they aren't really one thing or the other. At least with Schizophrenia, the person had an idea what that was like. In many cases the condition where there is no longer any schizophrenia is completely foreign.

      Also, depression is a poor example here. Depression is one of the most treatable and common mental health problems that people get treated for. Most people will have minor depression at some part of their life and major depression, while less common, is at least comprehensible via analogy to that.

    36. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      And if you start to suspect that the trip won't end, it gets significantly less awesome.

    37. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      No, they don't contradict each other at all. And that attitude is why the mental health profession is such a shit hole.

      We don't treat people who aren't very well organized as if they're sick, but we expect them to learn how to get organized anyways. We also, despite my protests to the contrary, don't consider people that like listening to Justin Bieber to be mentally ill, but they should really get better tastes in music.

      The point is that if we treat these people like they're mentally ill, it's not terribly inviting and you'll fight the brain the whole way. If we approach things as being about figuring out how to more effectively manage ones life and completely ignore any mental illness, you're no longer fighting the brain as much. The patient is more in control of the process and doesn't need to defend himself against the doctor.

      Coincidentally, that focus on disorder is a huge reason why people don't come in for treatments that might actually be helpful. Because there's this idea that only nuts come in for therapy, people won't come in. And when they do, they wind up with some sort of diagnosis as insurance won't pay without a diagnosis. But, the diagnoses themselves lead to further discrimination by other doctors and the public at large.

    38. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      the disease model isn't too far from the truth.

      I have no problem with people who are depressed wanting to do something about their depression. I also have no problem if that something is a drug.

      But I have huge problems with calling depression a disease. It just feels like a step towards "you have this 'disease', therefore, for your own good, we are taking away your right to make decisions for yourself".

    39. Re:Then I guess you could say... by Anonymous Coward · · Score: 1

      Sadly, there's a lot of this in my family. A lot of the ducking out of the view of windows because the Mafia, Nazis, ex coworkers, etc are out to get them.

      The disease seems to push them to apply the strongest knowledge and reasoning they have to create an explanation for what they're experiencing. The reasoning can require amazing government coverups, conspiracies, religion or technology.

      Even when medicated, the memories of the hallucinations are still treated as real. The bad guys just stopped bothering them for a while.

      Perception of reality, to the depth of memory and world view are all skewed.

      Society only frequently encounters higher functioning schizophrenics. They generally don't see the bat-shit-insane horror of the disease. People seem to be left with romantic visions of super-intelligent people, burdened with their creativity, just needing to be understood. Sure there are some of those, but they don't see the person who beats the shit out of their mother daily for no clear or understandable reason, the woman who runs away from home because she thinks everyone's been replaced with robots, and no word of a lie, the guy who chases an innocent stranger of a woman down the street because he thinks that she's concealing the fact that she's the magical embodiment of a unicorn.

    40. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      I have met someone whom I'm pretty sure has schizophrenia. He has those kind of cognitive delusions, blocking out all form of logic other than his own. But one thing I did notice is how if the person going against his ideas is held in very high regard, he just kind of seems to go with their opinion, although clearly internally and very highly disagreeing with it. It's very interesting because up until today I've seen him work with 10-20 people and only one of them managed to get some work done, not because he imposed his views, but because he was held in high regard. What's your take on this?

    41. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      Plus there are people who rock the boat a bit too much. Folks who take "free speech" literally. They will be harassed until they end up in the psych ward. And sure as hell the military and the special services have highly developed methods to get this done. The only difference to the KGB is that their methods are less obvious in the "free world". Well, sometimes. Sometimes they give you the Mk1 Eyeball or the Mk1 Dog Bark treatment. And surely they expect you to commit suicide on this. This world is controlled by dark forces, which are actually the other side of our consumerist coin.

    42. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      AC, have you tried changing your diet? It sucks, but after I completely eliminated wheat, dairy, preservatives and anything from the genus solanaceae (nightshade vegetables), I got no more hallucinations. Also got rid of some similar symptoms that I didn't even realize weren't normal. I actually thought the sensation of bugs crawling on the skin was much worse than the auditory hallucinations, but mine weren't that loud either.

    43. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      My SO works in a library and encounters a lot of people with poorly managed disorder, schitzophrenia among them.

      What she finds interesting is the degree of focus they can bring to researching their supposed tormentors - whether it's RFIDs that someone has installed in their brain, or radio waves, or the dust devil that has a demon in it, or [insert phenomena here], they try to find solutions. Because their thinking is disordered, their research is ultimately not useful (because it focuses on what is, at base, a symptom rather than an etiology). Nonetheless, their utter devotion and focus make it clear that they're not 'broken,' just not operating with a high-functioning set of input filters.

      Imagine what they could accomplish if their ability to filter real from imagined is improved.....

      And since the original article talks about genetic bases, I wonder whether nor not those genes confer any advantage when all of them are not combined in a single individual? Maybe it's a storyteller gene, or an imagining gene, or visualization.....who knows?

    44. Re:Then I guess you could say... by omnichad · · Score: 1

      I have a feeling that part of what afflicts people like you is a superior ability of pattern recognition. Unfortunately, that means you can "hear things" in the background noise of the world and they are recognized as voices and words.

      I would assume that it's closely related to genetic advantages that would allow you to learn people's faces more easily.

    45. Re:Then I guess you could say... by omnichad · · Score: 1

      Probably pattern recognition. If innocuous background noise is perceived to be intelligent data, the brain amplifies it (isolates / focuses) rather than filtering it out. It's possible that the voices go away in complete sensory deprivation.

      On the other hand, some studies show people born deaf also have language hallucinations - in sign language or lip movement.

    46. Re:Then I guess you could say... by Rich0 · · Score: 1

      I don't think people appreciate how biological reasoning actually is, and just how modular the brain is, with every part having to trust the other parts to do their jobs. Your reasoning might be perfectly intact, but perhaps your visual perception has a problem, which means that you're going to make bizarre decisions.

      You can have a brain that does 95% of everything spot-on, but some very specific abnormality causes really bizarre cognitive functionality.

      Just talk to anybody young who had a serious stroke. They could probably describe just how things changed for them, what did and didn't recover, and so on. In the beginning they might have been completely oblivious to there even being anything wrong - sometimes they perceive everybody around them as suddenly becoming dumb/etc.

    47. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      Depression IS a disease, in many cases (like mine) caused by a genetic miscoding for production and control of the protein serotonin (one of the major neurotransmitters).

      With serotonergic drugs I have a life at the high end of high tech R without them I cower under the bed in biochemically-caused panic, overwhelmed by feelings of imminent death/worldwide doom, and completely unable to use my broken brain: can't add, can't speak clear sentences, can't think straight.

      In some people the disease is transient, caused by the stresses of life (the average human has 2 - 4 major depressions in a lifetime) like loss, trauma, whatever. In some people, it's chronic (bad genetics).

      If you're lucky, there's a medication that manages your depressive disease. If you're not lucky (like me for the first 54 of my 58 years) there is no medication that treats it and you live in hell.

      Depression IS a disease, usually of genetic etiology, just like diabetes is a disease (genetic; problems with production and control of the protein insulin). Get over it.

    48. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      This maniac focus also has to do with the fact that the mis-wired brain is pumping out such massive doses of various chemicals that behavior is truly skewed but with massive power behind it (many schizophrenics have lesions in their brains from the abnormal amounts of various neurochemicals dumped there over time).

      Imagine drinking three liters of caffeine and what your brain would be firing like; for many schizophrenic or BPAD folks, that chronic, unmodulable, overdriven state is reality.

    49. Re: Then I guess you could say... by Anonymous Coward · · Score: 0

      Personally, I excel at pattern recognition, but I suck at facial recognition, as well as remembering names. If a name is unusual, I can remember it though. Faces will stick eventually, but names I've known for years will slip.
      I can read a technical fact once and remember it forever though.

    50. Re:Then I guess you could say... by david_thornley · · Score: 1

      Huh? I've not been given the impression that anybody wants to take away my right to my own decisions because of any disease, whether it be flu, coronary artery disease, or depression. (They do want to monitor suicidal thoughts with depression, but that's not the same thing.)

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
    51. Re:Then I guess you could say... by david_thornley · · Score: 1

      If you completely ignore the illness, you're not doing much good (at least in cases of depression). A lot of depression therapy is about managing depressive tendencies, which is working with the patient, not on the patient, but does require acknowledging the mental illness.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
    52. Re:Then I guess you could say... by Bobakitoo · · Score: 1

      And the next baby after the abortion would be all these things minus the schizophrenia. Or were you implying that it is schizophrenia that made him a 'beautiful person', 'very generous' and a 'musician'? Because I know a lot of peoples just like that and they are not schizophrenic.

    53. Re:Then I guess you could say... by Anonymous Coward · · Score: 0

      > But I have huge problems with calling depression a disease.

      Why, because it affects the brain instead of some other organ?

    54. Re: Then I guess you could say... by Anonymous Coward · · Score: 0

      It great that depression is treatable fothoe it works on. Its a bitch for us that it doesn't. Genetic tesiting will help sort us out and hopefully point in the direction to drugs & treatments that help.

      To better days,

    55. Re: Then I guess you could say... by Smurf · · Score: 1

      Or he could just be referring to the etymology of the word schizophrenia: from schizo, split, and phren, mind.

  2. not a single disease. by Anonymous Coward · · Score: 0, Funny

    We agree.....

  3. i knew that. by jaeztheangel · · Score: 3, Funny

    well, when i say 'I', its more of a consensus decision.

    1. Re:i knew that. by Anonymous Coward · · Score: 0

      Look at the time of their postings. One minute between the two. Not enough time for " jaeztheangel " to have seen the AC's post and copied it, that's why I modded both of them up 'funny'. Posting AC (having logged out first) because of it.

      ++++ Captha - 'Socially'

    2. Re:i knew that. by cold+fjord · · Score: 2

      We are not amused.

      --
      much of left-wing thought is a kind of playing with fire by people who don't even know that fire is hot - George Orwell
  4. Schizophrenia is not multiple personality disorder by mod+prime · · Score: 4, Informative

    AKA Dissociative identity disorder. There is a slight comorbidity between the conditions, but depression and anxiety are also comorbid.

  5. DNA? by sumdumass · · Score: 4, Interesting

    If it is embedded in DNA, is it hereditary?

    If it is, I hope it does not bring back Eugenics or the forced sterilization practices of the early 19th century. That didn't end well on several fronts.

    1. Re:DNA? by Anonymous Coward · · Score: 0

      Early 19th century? In Canada, the Alberta Eugenics Program was active until 1972. Sterilized a bunch of people. Efficient program; they spent about 13 minutes on average to decide on a case.

    2. Re:DNA? by rtb61 · · Score: 2

      Let's be honest there is quite a bit of difference on a planet with 7 billion people to enact laws making procreation and child rearing a privilege and responsibility only for those appropriate to do so versus you can spit out all the ones you want expecting the rest of society to care for them and take responsibility for them, this versus extermination camps.

      Suck it up, despite all the whining about how badly it was done in the past it will not ever stop all of us or future generations from biting the bullet, it is a matter of inevitability or total collapse from the 20 billion idiocracy taking over and an extinct species replacing them.

      A whole lot of problems can be safely easily eliminated in a generation or three or we can continue to fail future generations with them.

      --
      Chaos - everything, everywhere, everywhen
    3. Re:DNA? by nine-times · · Score: 1

      It's been known to be hereditary for a long time, as have many other diseases that haven't caused us to have forced sterilization. Why do you think we'd start now?

    4. Re:DNA? by Anonymous Coward · · Score: 0

      If it is embedded in DNA, is it hereditary?

      I don't know, ask a Hungarian.

    5. Re:DNA? by Anonymous Coward · · Score: 0

      Why would this bring back eugenics more than any other disease? We have plenty of disorders with genetic components running the gammut from mildly irritating (normal life span) to incompatible with life outside the womb for an extended time. Why would this one in particular lead to a reintroduction of forced sterilization?

    6. Re:DNA? by Anonymous Coward · · Score: 4, Insightful

      You will be amazed at how few babies people have once you give them (especially women) access to birth control (and the realistic ability to use it without terrible social stigma), as well as a livable income.

      The stats have shown this throughout history....high birth levels are associated with poverty, and also with the unavailability of (completely voluntary) birth control. The wealthy class across the globe generally has zero or one child per couple, whereas indigents generally have 5 or more per couple. And government funded birth control being freely given to the populace has also been shown to significantly reduce birth rates.

      Before you go sterilizing people, consider that there may be a much more just and humane way of achieving the exact same goals, and making everyone involved a whole lot happier about it.

    7. Re:DNA? by sjames · · Score: 1

      Waiting to put on a black shirt?

      Who is first on your extermination list?

    8. Re:DNA? by alvinrod · · Score: 2

      That's one way to look at it. Another is that we'll strive to develop the techniques and technology that can be used to correct this problem through medical intervention. That ability would go a long way towards being able to cure several other hereditary diseases as well. Perhaps being able to meddle with our own genetics will end even more poorly, but we'll likely learn something along the way.

    9. Re:DNA? by NotSanguine · · Score: 1

      Let's be honest there is quite a bit of difference on a planet with 7 billion people to enact laws making procreation and child rearing a privilege and responsibility only for those appropriate to do so versus you can spit out all the ones you want expecting the rest of society to care for them and take responsibility for them, this versus extermination camps.

      Suck it up, despite all the whining about how badly it was done in the past it will not ever stop all of us or future generations from biting the bullet, it is a matter of inevitability or total collapse from the 20 billion idiocracy taking over and an extinct species replacing them.

      A whole lot of problems can be safely easily eliminated in a generation or three or we can continue to fail future generations with them.

      Absolutely. Let's start with you. Seems reasonable to me. Do I hear a second?

      --
      No, no, you're not thinking; you're just being logical. --Niels Bohr
    10. Re:DNA? by Anonymous Coward · · Score: 0

      Eugenics was primarily advocated by progressives and Democrats (check for yourself if you don't believe me). They don't need to bring it back, they have new ways of screwing minorities (affirmative action, multiculturalism), plus the tried and true battery of old schemes (Keynesianism, minimum wage, public education, etc.).

    11. Re:DNA? by Risha · · Score: 1

      Like bipolar disorder, it's been known to be at least partially hereditary for decades. I don't think this particular study is going to bring out the pitchforks and torches.

    12. Re:DNA? by Anonymous Coward · · Score: 0

      Well, since you asked...

    13. Re:DNA? by Anonymous Coward · · Score: 0

      What do you mean bring it back, look what happens to humans with the wrong chromosomes in many countries right now. http://www.nybooks.com/articles/archives/1990/dec/20/more-than-100-million-women-are-missing/

      And yes I know that is a bit of a diversion but it shows how frequently a very similar decision is made right now, DNA testing for such diseases will just accelerate the use of the process.

      I have nothing to say about the ethics of such behaviour however I do suspect that there may be hidden risks that result in the creation of a mediocre population when genius and mental illness are closer to each other than they are to "normal".

    14. Re:DNA? by Anonymous Coward · · Score: 0

      How about we go with his second option, extermination. Apparently these are the only two choices, so why not just go full evil instead of evil light?

    15. Re:DNA? by Anonymous Coward · · Score: 0

      Early 19th century? In Canada, the Alberta Eugenics Program was active until 1972. Sterilized a bunch of people. Efficient program; they spent about 13 minutes on average to decide on a case.

      Pity I wasn't on the council; I'd have sterilised me in a heartbeat.

      Wait, what?

    16. Re:DNA? by Anonymous Coward · · Score: 0

      Like a form of diabetes or being many times being stupid? I vote we sterilize people who are jerks before we touch people with health issues. So anyone trying to pass Eugenics should first need to be sterilized because they're both stupid and jerks.

    17. Re:DNA? by LeadSongDog · · Score: 1

      What if instead of sterilization we pass laws saying that if you knowingly and willingly pass defective genes on to your kid, you'll get prosecuted just as though you'd harmed them through abuse. For example, if a couple knew they were both carriers of the cystic fibrosis gene, they had a kid anyway, the kid had CF, and died at age 20, they would go to jail for murder.

      captcha = "condom"

      That would certainly discourage people from getting tested...

      --
      Oh, I'm sorry sir, I thought you were referring to me, Mr. Wensleydale.
    18. Re:DNA? by omnichad · · Score: 1

      Life is a fatal condition. Putting arbitrary value on specific lifespans that you deem acceptable aren't as eugenic as you believe.

    19. Re:DNA? by Anonymous Coward · · Score: 0

      I think the unasked question is whether it is ethical to enact restrictions regarding whether a person may genetically parent a child.

      My two cents: I don't think the right exists, notwithstanding the fact that it could (in extremely remote theory) improve humanity by removing genetically proven genetic liabilities from the gene pool, mostly because it would be impossible to administer without bias - human beings are not objective. While I definitely think there are people who have children who would probably leave the world a better place by not doing so, it's not my right to tell them that.

      While it might be a case where someone with x genetic markers would have their reproductive rights curtailed, 'genetic markers' could be used which identify people from particular ethnicities or morphology with known shared issues - Sickle-cell, for example, or Tay-Sachs - and used as a weapon of prejudice, which I'd argue would be wrong.

      Sigh. If humans were rational actors.....but in the final analysis, we're really not. We'll have to muddle through as we always have, and work for the best outcomes we can.

    20. Re:DNA? by rtb61 · · Score: 1

      I'll second that moron, check before you make statements and if you can't check don't assume otherwise you'll make an ass out of yourself.

      --
      Chaos - everything, everywhere, everywhen
  6. 5 Ridiculous Myths You Probably Believe by tepples · · Score: 3, Interesting

    I wonder if the depression and anxiety are more side effects of the medications used to treat schizophrenia, or effects of trying to avoid discrimination against people with schizophrenia due to its misrepresentation by Hollywood, as a recent Cracked article suggests.

    1. Re:5 Ridiculous Myths You Probably Believe by mod+prime · · Score: 5, Interesting

      Well - they make you feel a little sluggish, and quite drowsy for about 8 hours (more at higher doses) after they kick in (so don't take them for breakfast if you have plans), but not depressed. It is possible to feel despair because of your chronic condition and the prospect of long term sluggishness I suppose but

      Schizophrenics who seek help often do so for anxiety and depression rather than psychosis. There is often a history of these issues predating medication, but not always.

      It's not just Hollywood, it's everywhere. The psychotic=violent myth is in every media that has discussed the issue. Newspapers only mention schizophrenia if someone was hurt, furthering the association in people's minds. My current employer refused to let me work without supervision because I had advised them I have had psychotic episodes and am undergoing treatment until I gave them a psych's letter telling them they were being morons (small and new business, so I forgave and educated instead).

    2. Re:5 Ridiculous Myths You Probably Believe by BarbaraHudson · · Score: 2

      Part of the problem is that some schizos ARE dangerous - we just don't know ahead of time who they are. If this lets us tell the two apart, awesome. Of course, there's the problem of false positives, as well as the question of environment (does a tendency to be dangerous still need an environmental trigger to manifest itself)?

      Unfortunately, all meds have side effects. It's up to the patient, in consultation with their doctors and therapists, to find the right balance, which can change over time. "I feel fine now, I guess I don't need this anymore" is almost always a lie, but a tempting one.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    3. Re: 5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 0

      Part of the problem is the readers' definition of violence.

      Societal, familial and self are three distinct area of concern. /. Sharp knives can kill or cut apart stigma;)

    4. Re: 5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 0

      A less acknowledged fact is that the proportion of societal violence attributable to schizophrenia is small.

      http://m.bjp.rcpsych.org/content/180/6/490.full

    5. Re:5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 0

      The problem with meds is that they aren't a treatment, they are at best a bandage. The closest thing there is to a "cure" for these disorders is psycho-social education. Get the brain to start rewiring things and teach these people how to evaluate their perception of reality.

      Medication is useful in the short term to get people close enough to start seeing things the way that other people do, but if a person is taking medication for the long term, it's more likely to be professional incompetence than actual necessity.

      And yes some are dangerous, but most of the time it's because people aren't educated about how to deal with folks that aren't on the same page. I knew a medication nurse that had spent decades working at the lockdown ward of one of the local hospitals, and during her time there they only had to restrain one patient. As in, that was the only time that they needed to restrain a patient because they got out of control And considering that the lockdown ward generally has the most ill most dangerous patients, I think that's a good indication of the actual risk factor there.

    6. Re:5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 0

      Part of the problem is that some schizos ARE dangerous

      So are sociopaths and psychopaths. What you are trying to imply is that schizophrenics are more dangerous than other mental disorders. That claim is A) not factual and B) a matter of perspective. Is a person capable of stealing people's life savings as dangerous as a person that may harm or kill a person? Personally I would say the sociopath has the capacity to do far more damage, but I also consider that the sociopath will be out of jail repeating crime much sooner than a violent criminal. They can also target many more people prior to being caught than the violent criminal which causes much more damage to society.

    7. Re:5 Ridiculous Myths You Probably Believe by dcollins117 · · Score: 4, Insightful

      The problem with meds is that they aren't a treatment, they are at best a bandage.

      For the majority of medical afflictions being treated today there is no cure, so the best doctors can do is offer palliative care.

      There is no cure for cancer, heart disease, athsma, arthritis, or even the common cold. So little is known about the human brain that zero percent of psychological disorders are effectively treated. Whenever I hear a doctor brag about how much they know about the human body or worse a psychologist remark about how much is known about the brain I always remind them how much there is they don't know.

    8. Re:5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 0

      No they often go together and are seen together before prescribed meds. In some ways, it can be one's realization that one's anxieties aren't getting calmed in the foreseeable/believeable future that can be what is truly depressing, for lack of a better term.

    9. Re:5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 0

      Paranoid schizophrenia is what most psych worlers dread the most or is close to the top. Especially when the patient has command hallucinations.
      "God told me to gouge out my eyeball". Etc.

    10. Re:5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 1

      That's far too pessimistic. Consider lymphomas in children, which used to be invariably fatal. A solid majority of them now go on to live normal full lives with no recurrence after a single (though unpleasant) bout of treatments. Or how about testicular cancers, where the no-recurrence rate is now something like 95%? If anything, cancers might be the field where we have the most truly curative treatments, apart from the things that can be corrected by surgery.

    11. Re:5 Ridiculous Myths You Probably Believe by Antique+Geekmeister · · Score: 1

      > There is no cure for cancer, heart disease, athsma, arthritis, or even the common cold.

      Your definition of "cure" seems quite odd. "cancer" can include quite modest, benign lymphomas, easily and safely excised. Some types of heart disease, such as pericarditis, are very effectively cured with antibiotics. "asthma" can include environmental asthma, easily handled by getting _out_ of cities and moving to a beach can handle it quite effectively. Many cases of mild Type 2 diabetes are effectively cured by weight loss, exercise, and diet. Arthritis is harder, but the common cold is any of hunderds or thousands of minor infections, and almost all of those are cured by supportive care and time.

      There's no "apply this medicine and it is gone" for most of them, but for some, well defined treatment can cure many cases.

    12. Re:5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 1

      Psychotic=violent is not a myth. It may not be the absolute rule, but it is far from being a myth, and the suggestion that it is reeks of dishonesty.

      I am the primary caregiver for an especially physically aggressive paranoid+disorganized schizophrenic. I find that people don't go far enough with psychotic=violent. Perhaps it's the, now, years I've spent at the front line of care, but whenever I see advocacy groups and high-functioning schizophrenics spin schizophrenia into a quirky eccentricity that can be managed fairly easy without threat to others, I am enraged. I have rushed home to find police cars waiting for me because that hour I spent out trying to work afforded my adult schizophrenic family member opportunity to "attack" the neighbor's physical house as retribution for the neighbor being a high-ranking general in a foreign military that has been spying on her for over 30 years. My schizophrenic believes she is fed a constant stream of information and data from an unnamed operator on board a satellite who also uses that satellite fire lasers to burn her teeth and gums. My schizophrenic also regularly talks about killing people. If you're being treating by meds, that means you're only as good as your meds and your regimen in taking them are.

      Perhaps, experience has colored my bias, but given what a psychosis is frankly, how can anyone say that psychotics are not inherently dangerous? You may believe you are non-threatening; however, this is your perspective, the perspective of someone who is admittedly psychotic. I emphasize with your situation, and I realize that my situation involves a more extreme case. Schizophrenia is certainly not one-size-fits-all. However, I can't blame people for being fearful. I live every day of my life in utter fear. If anything, Hollywood (at least within the last 20 years) has been very good to psychotics. Even on crime shows like America's "Law & Order" series, violent psychopaths are made more well-rounded. There is an attempt to show that they are people. This is a notable contrast to the crime dramas and movies on the 1980s, films like Cobra and Tightrope in which psychopaths are one-dimensional animals.

      The actual amount of violence crime attributed to schizophrenics is said to be quite low. I don't find comfort in that, if true. The ratio of schizophrenics to non-schizoprenics is sufficiently low by comparison. The question I would be curious about is, what percentage of schizophrenics ultimately commit violent acts during an episode I would consider a schizophrenic who has thrown rocks at a neighbor to be point toward that percentage the same as one who murders a caregiver. We can't only count violent acts that end in death or police reports.

    13. Re:5 Ridiculous Myths You Probably Believe by dcollins117 · · Score: 1

      My definition of "cure "is when people stop dying of these diseases. My point was that medical doctors and psychiatrists in particular have but a tenuous grasp on the actual workings of the human body. Many doctors contend if you have a mental illness that it is not a medical problem. You have to go see a psychiatrist for that. As if the brain weren't part of the human body.

      If you want to cherry-pick cases where where medical science reigns supreme, I'm all in favor of antibiotics. I will gladly join you in celebrating that success. However....

      Remember Ted Kennedy? Great guy, guzzled Chivas and often pulled his pants down during parties on Martha's Vineyard? He's dead. Got glioblastoma, didn't last much more than a year despite having the best doctors in the world.

      How about Randy Pausch? He was fully aware how well and truly fucked he was by pancreatic cancer, even made a video about it. He's now six feet under.

      Let's not forget Richard Feynman, being blessed with two forms of cancer, liposarcoma and WaldenstrÃm's macroglobulinemia. Suffice to say it didn't end well.

      Then there's Patrick Swayze, Farrah Fawcet, Gilda Radner, Peter Jennings, Sydney Pollack - I don't see much point in continuing this particular litany, having abundantly made my point already.

    14. Re: 5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 0

      A less acknowledged fact is that the proportion of societal violence attributable to schizophrenia is small. http://m.bjp.rcpsych.org/conte...

      Possibly because the number of schizophrenics is small, and the fact that the disease makes people ineffective at being surreptitiously violent disallowing for repeat offenses without being caught; plotting someone's demise with invisible conspirators tends to draw attention. A more interesting number is what percentage of schizophrenics turn violent versus what percentage of "normal" people, and statistically for what reasons? My hypothesis is that normal people have a smaller percentage - if not absolute numbers - who turn violent for petty or imagined reasons.

    15. Re: 5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 0

      I would stress more the definition of violence. Society as so much stigmatised male, physical violence, but little has been done of the female psychological violence which in many ways can be far more damaging over time.

    16. Re:5 Ridiculous Myths You Probably Believe by BarbaraHudson · · Score: 4, Interesting

      Part of the problem is that some schizos ARE dangerous

      So are sociopaths and psychopaths. What you are trying to imply is that schizophrenics are more dangerous than other mental disorders.

      I never came near implying that. Not once did I mention sociopaths OR psychopaths. To the contrary, I wrote that if this finding lets us tell the dangerous schizos from those who aren't, this will be awesome. My answer presumes that many schizos are not dangerous. I even went further, posing the question of whether a tendency towards violence might still need an environmental trigger.

      A real-life example from one of my classmates in high school. Diagnosed as schizophrenic at 8 years of age, his father basically tried to "beat the devil out of him" for the next 8 years. That's akin to pounding on a bomb to see if it's armed. Even if he wasn't dangerous before, this course of conduct almost certainly lead to "arming the bomb." He beat his father to death right in front of me, and I was next on his list. He was found to be not criminally responsible, in part due to my testimony, and having seen and heard what he did that night, I believe the jury got it right.

      Does that sound like someone who's unsympathetic to the problem?

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    17. Re:5 Ridiculous Myths You Probably Believe by angel'o'sphere · · Score: 1

      You seem not to understand your parent: for most cases you mention: is no cure!
      Only adapting/changing your lifestyle and time cures it.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    18. Re:5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 1

      Psychiatrists are medical doctors. It's a specialty, like gastroenterology or orthopedics. They go through med school, then additional training. You go to a family practice doctor and they send you to a psychiatrist, they're not saying it's not a medical problem they're saying it's beyond their training - which is a damned good thing for them to do. If I'm sick, really sick, I want to see a specialist. Don't you? Psychologist aren't medical doctors, they're PhDs, and have their own certificates. A good MD would know when a psychologist or a psychiatrist is correct, and either of those should know when a neurologist would be warranted. But it's not like humans come with particularly good diagnostic code reading systems.

      Cancer is a very broad term. It's like "infection." People still die of infections as well as cancers, so you might as well say that infections are fatal and untreatable. Infections have a higher rate of successful treatment, but neither is treated successfully 100% of the time, nor 0% of the time. Numerically, most cancers are successfully treated. No one is saying that's good enough.

      Look, pretty much all animals die. You're cherry picking if you say otherwise. If you're whinging that medicine hasn't been able to prevent death in humans, you must have a very depressing life and absurdly high expectations of what the limits and pace of science are.

    19. Re:5 Ridiculous Myths You Probably Believe by Rich0 · · Score: 1

      My definition of "cure "is when people stop dying of these diseases. My point was that medical doctors and psychiatrists in particular have but a tenuous grasp on the actual workings of the human body.

      To be fair, many of these "diseases" are just labels applied to general classes of symptoms, which probably have many underlying mechanisms. It is a bit like saying we haven't come up with a cure for "ache" yet, even though many conditions that cause aches do in fact have genuine cures.

      Many doctors contend if you have a mental illness that it is not a medical problem. You have to go see a psychiatrist for that. As if the brain weren't part of the human body.

      Heck, I can't figure out why in the US dentistry is treated differently than any other form of medicine. I can appreciate that insurers don't want to pay for cosmetic treatments like teeth whitening, but if I break any bone in my body other than a tooth, it is treated differently than if I break a tooth.

    20. Re:5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 0

      "Normal" people are violent enough; I'm sure they've got the shizos covered...

    21. Re:5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 0

      Study of the genome and the "broken" bits that code for disease will turn this whole game around. When we can introduce into the body the CORRECT biochemisty to patch around the "broken" biochemical pathways, we'll be treating disease with what the body needs, not some analogue or something that somehow fools the body as with most current treatments. Effectiveness will go up, side effects will go down, and won't that be something...

    22. Re:5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 0

      No, no: the Harvey the Dog, possessed by an ancient demon, demands of you the blood of pretty girls and, when you try to kill the dog to shut him up, "supernatural powers" prevent you from doing so.

    23. Re:5 Ridiculous Myths You Probably Believe by mod+prime · · Score: 1

      Psychotic=violent is not a myth. It may not be the absolute rule, but it is far from being a myth, and the suggestion that it is reeks of dishonesty.

      The equals sign makes it absolute. One equals the other. They are the same. That's as absolute as you can get. There is an increased chance of violence in psychotics and it is considerable but the equation tars me with a brush unfairly.

      This would be like instead of saying 'If you are black, there is an increased chance you are involved in crime' {in the USA, presumably a function of poverty and entrenched gang culture etc} but instead saying "All black people are criminals".

      It's unfair and its harmful. Please stop it.

      You may believe you are non-threatening; however, this is your perspective, the perspective of someone who is admittedly psychotic.

      Totally non-threatening. I only kill secretive government spies who are trying to assassinate me. Either that or I've only ever been the victim of violence (a lot), not the perpetrator.

      If anything, Hollywood (at least within the last 20 years) has been very good to psychotics.

      Like what? Twelve Monkeys? Beautiful Mind? Donnie Darko? They're the most positive ones I can think of.

      Even on crime shows like America's "Law & Order" series, violent psychopaths are made more well-rounded

      Also, we'd appreciate it if you didn't conflate psychosis with {violent} psychopathy. Really, please never do this again.

      . The question I would be curious about is, what percentage of schizophrenics ultimately commit violent acts during an episode

      Until you learn the answer to this question please stop saying psychotics are inherently violent. Thank you.

    24. Re: 5 Ridiculous Myths You Probably Believe by Anonymous Coward · · Score: 0

      Some non schizos are dangerous too. In fact most violent murderers are non schizo. Should we just knock everybody out with chemical coshes too just to be on the safe side. It would also lead to massive pharmaceutical profits which must be good for jobs and economy.

    25. Re:5 Ridiculous Myths You Probably Believe by Swave+An+deBwoner · · Score: 1

      Yes, a pet peeve of mine.

      With all the hype and hoopla insurance companies have been ladeling out about "wellness" and "preventive care", the fairly well established correlation between poor dental status (decay, gum disease) and heart disease goes unmentioned lest their hypocrisy be uncovered. and their profits diminished.

  7. Helps explain a few things ... by BarbaraHudson · · Score: 2

    Helps explain why my dog reacts differently to different people with the diagnosis of schizophrenia. Some he's very friendly with, others he makes it abundantly clear that he wants nothing to do with them - or with them being around me.

    Dogs can sense a lot of things we miss - maybe they can pick up something about the dangerous ones that we can't. And yes, one of the ones he kept growling at eventually went looking for a gun. Told my neighbor (who has 3 registered hand guns) that he hated my guts and where could he buy a gun? Stopped a few weeks later after dusk walking around with a holster with what appeared, in the dark, to be a gun. Knees on the ground, hands in the air, the whole bit. Apparently he wasn't happy that I had reported him to Youth Protection for moving back to the neighborhood after he had assured the court he wouldn't be having any more contact with a kid living in the next building.

    --
    "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    1. Re:Helps explain a few things ... by linuxrocks123 · · Score: 2

      Or your dog could just not like certain people because they smell bad to him. Some schizophrenic people have poor hygiene. Or maybe the dog doesn't like the color of their skin. I met a racist dog once -- it was hilarious :)

      In any case, I think it's more likely a coincidence of some sort than the dog peering into someone's soul. Remember, we're the species with orders of magnitude more neurons than everyone else, and dogs are about as smart as small children.

      --
      vi ~/.emacs # I'm probably going to Hell for this.
    2. Re:Helps explain a few things ... by BarbaraHudson · · Score: 4, Interesting

      Dogs have had many more generations of breeding to tailor their responses to us than we have had to them - something like 10x as many generations, since they breed about 10x quicker than humans. So they can read us much better than we can read them - they've self-selected for that ability, since the ones that can read us best know best how to suck up to us and get us to feed and shelter them and pick up their poop. Todays dogs are specialists - and their specialty is humans.

      Given this, dogs are probably better judges of people than we are.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    3. Re:Helps explain a few things ... by Anonymous Coward · · Score: 1

      I have seen dogs go crazy over the stupidest things - like nothing.

      And maybe the dog is taking a cue from you. For some reason you don't like these people so the dog growls. I have seen that happen many times.

      And I happen to have a schizophrenic brother who has many dogs that love him to death AND he has a dog sitting/walking business that is highly recommened. He loves dogs and they love him.

      Dogs love me too - and as far as I'm concerened, they should be eaten and not seen. I cannot stand those barking, shit eating, bred to stupidity by stupid people, digusting creatures - and those are their good qualities. Dogs have been bred for looks by idiotic breeders and as a result, they are stupid and prone to diseases

      So, as you were saying?

    4. Re:Helps explain a few things ... by ignavus · · Score: 1

      Given this, dogs are probably better judges of people than we are.

      Clearly dogs should be employed in recruitment departments.

      --
      I am anarch of all I survey.
    5. Re:Helps explain a few things ... by linuxrocks123 · · Score: 5, Insightful

      That's an interesting hypothesis. But I don't buy it, certainly without some scientific testing (versus emotional, speculative anecdotes from people with dogs). Evolution doesn't work like leveling up in a video game. Once a local maximum is reached, further generations have no impact. I would also wager that, while there may have been some selection pressure to "read" a person's immediate emotional state, selection pressure for reading general personalities, etc. was likely much weaker. And, of course, the selection pressure for humans to "read" other humans would have been much, much greater. After all, we have to mate with each other. Dogs don't have to mate with us. They do, however, have to mate with other dogs, and interaction with other dogs probably dominated the selection pressure on dogs' social intuition faculties. So, I would speculate people are likely better judges of people than dogs are.

      What probably happened with the schizophrenic people was perhaps they were anxious, because of delusions or whatever, and the dog picked up on that. You probably also did. That you had a single negative interaction with one person your dog didn't like is not an important piece of information, if we're going to go about this scientifically. But, hey, I'm speculating too. Someone would have to research this. How and why, I have no idea. But my speculation can beat up your speculation :P

      --
      vi ~/.emacs # I'm probably going to Hell for this.
    6. Re:Helps explain a few things ... by Antique+Geekmeister · · Score: 1

      > Once a local maximum is reached, further generations have no impact.

      Except when they do, of course. Cross breeding can profoundly remix different 'local maxima' and even produce new breeds. Environmental changes, or changes in other species, can also interact profoundly with inherited characteristics, and some genes are even activated or de-activated by environment. And canine behavior isn't merely genetic, it's trained by the limited culture in dog families, and by the humans they interact with.

      Dogs are likely to have a _different_ set of criteria for judging people. And people are under enormous personal and evolutionary pressure to lie effectively, espefcially to other people. So I'm unsurprised when a colleague's dog has a very different sense of whom they like when visiting the office. I have noticed that the dog's opinions about new hires seem to match my long term opinions, and it's not even my dog.

    7. Re:Helps explain a few things ... by Anonymous Coward · · Score: 0

      Dogs love me too - and as far as I'm concerened, they should be eaten and not seen.

      Nice twist on a classic there, Hannibal.

    8. Re:Helps explain a few things ... by Anonymous Coward · · Score: 0

      I would bet your dog does not like the ones with anxiety problems.

    9. Re:Helps explain a few things ... by BarbaraHudson · · Score: 1

      I would bet your dog does not like the ones with anxiety problems.

      To the contrary. I have PTSD, and he's been a real lifeline when things have turned pear-shaped. Dogs have helped me hide it for decades, because getting treatment wasn't easy. Now, while I was finally able to successfully get help in the last year, I will always need a dog - which is okay. It's better than the alternative.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    10. Re:Helps explain a few things ... by Anonymous Coward · · Score: 0

      Question is, would you always need a "hotdog", Frank N. Furter? Apparently not. You had your 'frankfurter', surgically removed, hahahaha!

    11. Re:Helps explain a few things ... by airdweller · · Score: 1

      "Helps explain why my dog reacts differently to different people with the diagnosis of schizophrenia. Some he's very friendly with, others he makes it abundantly clear that he wants nothing to do with them - or with them being around me. "

      Or, most likely, your dog just picks up on your attitude towards those people. They're great at that.

    12. Re:Helps explain a few things ... by BarbaraHudson · · Score: 1

      He wasn't picking up on my attitude. The guy who eventually went looking for a gun because he hated me? I had previously invited him and two of his relatives into my home, and had NO clue whatsoever as to why my dog was growling at him, and only him. I had pretty much an "open door" policy at the time, and he was one of several people he'd let come in, but not get close to me.

      He came in handy when another neighbor tried to "squeeze the Sharmin" and didn't want to take no for an answer. Could have used him in the subway a couple of years ago.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    13. Re:Helps explain a few things ... by omnichad · · Score: 1

      The local maxima for specific traits don't continue to "level up". 20/20 vision is about the best we're going to evolve (with a few minor outliers), because there's no genetic advantage to having better.

    14. Re:Helps explain a few things ... by linuxrocks123 · · Score: 1

      Both humans and dogs have had ample opportunity to cross-breed. Dogs' opinions of people are likely to based on the primitive, intuitive brain. I don't know how different their criteria would be. Their main purposes in judging people are probably going to be something like, "Is this person going to feed me, kick me, or kill me or my master?" Hardly conducive to a job interview situation. If you really think the dog is better at judging new hires than yourself or other humans, I suggest you let the dog perform an interview. I would make sure first, though. "You know, that DOG never liked this SOB from the start!" is likely to be subject to some pretty severe confirmation bias if you're not keeping records.

      It's pretty easy to experimentally verify this. Whenever you hire someone new, gauge how the dog likes the person, and how you like the person, and write that down in a journal. Six months down the road, go back and see who was right. After a sample size of 20 or so, decide whether to let the dog participate in the interview process. You might want to do this subtly so as not to freak the candidates out, but it would be pretty easy to be, like, "Hey, we have a dog! Doggy, say hi to !" without making it obvious you're getting the dog's opinion for hiring purposes. I'm surprised you haven't done this already. It's important to get as many people's -- er, creatures' -- opinions as possible when hiring someone.

      Personally, I'd be pretty pissed if someone passed me over for a job because a dog didn't like me, but unless the dog's being racist or sexist, I wouldn't have a leg to hump or to stand on in a lawsuit. Actually if I somehow found out that happened, I'd probably think some really negative things about the company and be kind of glad. But, hey, don't let broader society stop you. Do the experiments, then go with Dog.

      --
      vi ~/.emacs # I'm probably going to Hell for this.
    15. Re:Helps explain a few things ... by david_thornley · · Score: 1

      Why wouldn't there be a genetic advantage for better vision? I think we basically are running up against physiology here, and that we'd need to have somewhat different eyes to have greater resolution.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
    16. Re: Helps explain a few things ... by omnichad · · Score: 1

      What's the survival advantage of better than 20/20 vision? "Good enough" is really as far as natural selection can go.

    17. Re:Helps explain a few things ... by Reziac · · Score: 1

      Undoing some mod points to reply here, but anyway...

      Aside from how dogs have been selected to "read man" (see the results of testing police dogs, where it was found most were alerting not on drugs, but on handler expectations), a dog's nose can pick up even the slightest difference in a person's metabolism -- half a dozen molecules are sufficient for some dogs' noses to distinguish. In crude terms, when there's something "wrong" with the human's chemistry, which includes brain chemistry, they smell different from other folks (probably due to the metabolic byproducts being different). If that smells "wrong" to the dog, they're going to react against it, often with fear or aggression.

      This is also why some assistance dogs alert to their owner's health status -- I know a guy whose dog goes nuts if he's starting a diabetic episode, and he's learned (the hard way) the dog is right even tho he hasn't any symptoms yet. He starts smelling wrong to her, so she throws a fit, and she notices well before the blood test does. (He's done multiple tests in a row to check against her reaction.)

      Incidentally I have a dog who 'alerts' on certain abnormal personalities -- he's naturally trusting and loves everyone else, but acts like he wants to kill a very few individuals: One was a paranoid schizophrenic (among other symptoms, she heard voices and saw things that weren't there), another had bipolar disorder with severe anger issues, and so on. And this dog, who has an exceptional nose, visibly does the "take a sniff, then react" thing. I've learned that when this dog doesn't like someone, I had better pay attention, because he's always right.

      [I'm a pro dog trainer with over 40 years experience. I notice these things.]

      --
      ~REZ~ #43301. Who'd fake being me anyway?
  8. Eugen Fischer by tepples · · Score: 0

    If so, they're going to have to come up with a new name for Eugenics that isn't connected to Eugen Fischer, the National Socialist anthropology professor who taught the guy who taught Mengele.

    1. Re:Eugen Fischer by nine-times · · Score: 4, Informative

      Are you joking? "Eugenics" comes from Greek. 'Eu' meaning good, like euphoria, euphemism, or utopia. 'Genic', dealing with birth, breeding, and production, like in genetics, generate, or hydrogen.

    2. Re:Eugen Fischer by Anonymous Coward · · Score: 1

      I'd expect most people to interpret "eugenics" as the Greek stems for "good" and "genes", because that's where the word comes from. A fairly obscure nazzy doktor with a similar name isn't what tainted the word.

    3. Re:Eugen Fischer by tepples · · Score: 1

      Are you joking?

      Yes, in part. But proponents of eugenics will still need to disguise it to the public because Fischer or no Fischer, the public still associates eugenics with Nutsies.

      "Eugenics" comes from Greek.

      So does the name Eugene, which is rendered "Eugen" in German.

    4. Re:Eugen Fischer by Guy+Harris · · Score: 2

      I'd expect most people to interpret "eugenics" as the Greek stems for "good" and "genes", because that's where the word comes from. A fairly obscure nazzy doktor with a similar name isn't what tainted the word.

      I'd expect most people neither to associate it with the Greek stems in question nor with Eugen Fischer; I'd expect them to have no clue where the word came from.

    5. Re:Eugen Fischer by Anonymous Coward · · Score: 0

      Actually, the "u" in utopia means "not", u-topia = not a place. Reference

    6. Re:Eugen Fischer by angel'o'sphere · · Score: 1

      An utopia is not nevessaryly good and most definitely does not start with an 'Eu'.

      But perhaps not yor fault that americans don't know/care how to pronounce the 'eu' correctly, hint: 'joy' - 'eu' is pronounced correctly like the 'oy' in the enlish word 'joy'.
      And no, Zeus, is not pronounced Zoooooos!

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    7. Re:Eugen Fischer by nine-times · · Score: 1

      The word "utopia" comes from the Greek "eu" + "topos", i.e. "good place". The English spelling "utopia" is supposed to preserve the pun of confusing eutopia with "ou" + "topos", "no place".

      I don't know about modern Greek pronunciations, but in Attic Greek, "eu" wouldn't have been pronounced as 'oy', as in the enlish word 'joy'. At least not as far as I've ever heard. It would have been more like the "eu" in the english word "feud". My recollection is that the pun is used in Platonic dialogues, though I wouldn't be able to remember where it appears.

    8. Re:Eugen Fischer by angel'o'sphere · · Score: 1

      Sorry, but what is in you ears the difference between 'oy' in joy an 'eu' in feud? For me as a layman there is none.
      Your deduction of the word utopia is half right: It comes from 'ou' - nothing/none and 'tropia' - place, meaning 'no such place'. But 'ou' is not the same as 'eu', obviously. Hint: there are classic greek 'utopia' novels which make pretty clear what the origion of the word is :)

      How attic greek actually was pronounced, no one knows. But best bet is: similar to modern greek.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    9. Re:Eugen Fischer by nine-times · · Score: 1

      Sorry, but what is in you ears the difference between 'oy' in joy an 'eu' in feud? For me as a layman there is none.

      Well you implied that you weren't American, so maybe it's your accent? Because pronouncing the "eu" like you would in "feud" makes "Zeus" pronounced like "Zoooooos".

      How attic greek actually was pronounced, no one knows. But best bet is: similar to modern greek.

      Except for the fact that people have studied it quite a lot, and have a pretty good idea of how it was pronounced.

    10. Re:Eugen Fischer by angel'o'sphere · · Score: 1

      Well, than as a german I pronounce feud wrong.

      Except for the fact that people have studied it quite a lot, and have a pretty good idea of how it was pronounced.
      If that was the case, americans would not pronounce it wrong.
      And: you can not study the pronunciation of a DEAD language.
      EU is pronounced as the 'oy' in joy, believe it or not.

      And Achilles is not pronounced Ak-kill-as. However we get used those absurdities, it only makes watching movies like Troy a pain to the ears.

      Two greek protagonists holding up cups of wine and dropping a potion to the ground: "Toooo Zoooooos". The people in the cinema: 'hae?' ... well ... spilling some drinks is a sacrifice to the goods, we all know that. The third time it happens, people murmur: Oh! To Zoys! Thats what they mean ...

      If Zeus would be spoken Zoooos, it would be written Zous (in greek letters), but it is not ... ;D

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    11. Re:Eugen Fischer by nine-times · · Score: 1

      And: you can not study the pronunciation of a DEAD language.

      You can, and people do. In order to study dead languages (or dialects, or accents that no longer exist), linguists can sometimes find old writings from the time and place that describe how things are supposed to be pronounced. That makes things relatively easy. Without those kinds of sources, they can do things like analyze poetry or songs from the time, and figure out how the poetry was supposed to sound. They can look at puns and figure out which words were supposed to sound similar. It may not be a perfect science, but through years of studying these kinds of things, people can get a pretty good idea of how words were pronounced.

      EU is pronounced as the 'oy' in joy, believe it or not.

      Not in Attic Greek, it's not.

      And Achilles is not pronounced Ak-kill-as

      Well in the ancient Greek, IIRC, it would have been more like A-kill-e-oos (except the K sound would be a sound that we don't have in English), and Americans tend to pronouncing it as Ak-kill-ees, but that's neither here nor there. It sounds like you're maybe making the mistake of thinking that your German pronunciation is the absolute correct pronunciation, regardless of what language is being spoken or how the original language would have pronounced it.

    12. Re:Eugen Fischer by angel'o'sphere · · Score: 1

      mistake of thinking that your German pronunciation is the absolute correct pronunciation, regardless of what language is being spoken or how the original language would have pronounced it.
      Well, first of all, for most languages indeed german is very close to their pronunciations (includes wild examples like Finnish, Japanese, Hungarian, Turkish ... name one). The only two examples - from my mind - where it is not is english, and according to the writing, but less to the sound: French. However you certainly find native american or south american languages that are not easy to pronounce for germans, or african for that matter ... Thai comes to mind, or Cantonese)
      And second: I don't make _that_ mistake :) I can read greek, don't understand much, but can more or less fluently read a text aloud ... no greek complained so far, except for ancient rules of 'stressing' sylables.

      So, to paraphrase it, the only ones who have those ridiculous claims about attic greek are americans and to a lower extend englishs.

      The rest of the european world, especially the greek, pronounce it as I suggested. So, very strange if one part west of the atlantic deduces that from old songs and the other part east of it deduces the opposite. (Actually the 'american' ... and in this case only the american, not including the UK ... opinion about how latin is spoken is the same: completely ridiculous considering that we have 'reto romanic', romanian, italian, spanish, portuguese as counter examples :) )

      However your 'arguing' about how Achilles is spoken, nails it: Achilles is written in greek with the letter X (chi) as the second letter. So any 'k' sound in the middle is simply wrong.
      Look at the word TeX, a text setting (programming) language and how it is spoken, the 'ch' in our roman transliteration of the greek word Achilles corresponds to the X in TeX and is pronounced likewise :)

      My interpretation is: 100 or more years ago a small clique of american 'scholars' _invented_ the idiotic pronunciations of latin and greek and for some reason they became 'mainstream' or 'school knowledge' in the US ... and since a few decades or even a century no one challenged it.
      (I just saw an old history channel movie about the battle at the Thermopylae, it is so ashaming what nonsense the narrators are claiming ... unbelievable ... and most of them are habilitated professors in well named universities. Seems american really have trouble to simply read old sources and have the urge to reinvent/retry/reexamine half assed 'ideas' because they believe that is more accurate than an ancient text. And ofc as always the name Leonidas was a pain in the ear, but well, same for any other greek Hero)

      Reminds me a bit about the scene in the movie 'Star Gate' when the main character corrects the wrong translations.

      But it is always funny to meet americans on a 'latin conference' proclaiming they can 'speak' latin fluent and everyone is clapping his tights because of their 'accent' ...
      Granted however: my impression is much more americans actually _speak_ latin than europeans, only the 'accent' is funny.

      Btw, a friend of mine teaches classic greek, however she is a greek ... so perhaps she is 'preoccupied' :)

      Sorry, no point in arguing about it. All americans have a 'wrong' school education about how classic greek is pronounced ... I did not really want to make an issue about it, sorry if you actually learned classic greek, was mot meant as an offense.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    13. Re:Eugen Fischer by nine-times · · Score: 1

      no greek complained so far... the only ones who have those ridiculous claims about attic greek are americans and to a lower extend englishs.

      Ok, so what I'm taking away from this conversation is simply that you are a highly opinionated person who doesn't know what Attic Greek is. It's a dialect of ancient Greek, and it was not pronounced the same as modern Greek. So when I'm talking about Attic Greek being pronounced in some way, it's not really a sensible argument to say that I'm wrong because modern Greeks pronounce it differently. They're different dialects separated by thousands of years. It would be like insisting that people in Renaissance England used the same pronunciation as the English do today, when we know very factually that they did not.

      Your arguments, frankly, are crazy and ignorant, so I don't feel like arguing anymore.

    14. Re:Eugen Fischer by angel'o'sphere · · Score: 1

      I pointed out that a friend of mine is
      a) greek
      b) teaches modern greek
      c) teaches attic / classic greek

      I also pointed out that your illusional 'we can deduce how it sounded' is wrong, as there is no way at it would work for a DEAD language. We can only conclude from current pronunciations of similar words or from pronunciations of foreign words in other languages (imported greek words) etc. In rare cases we have dictionaries ...

      Further I would simply follow the majority. If one part of the world speaks Zeus like 'Zoys' and the other part speaks it 'Zoos' and the first part of those people is the majority, and lives very close to Greece and is philosophizing about that topic literally since millennia, while the other part is living in the 'new world' and is contemplating this topic since roughly 300 years and is the minority, then it is a safe bet that the 'majority (to which I belong)' is right.

      Finally, the absolute no brainer: why should those pairs of letters be pronounced the same:
      epsilon ypsilon
      eta ypsilon
      omega ypsilon
      omicron ypsilon
      ??

      Well, depending about which time we speak not all those letters existed anyway, perhaps that leads to further confusion.

      Btw: first sentence in the german article: http://de.wikipedia.org/wiki/Z... 'Aussprache' means pronounciation. And 'klassisch' means 'classic'.

      So, yes I was talking about classic greek all the time.

      Your arguments, frankly, are crazy and ignorant, so I don't feel like arguing anymore. Ignorant when I'm clearly right? ROFL. But this was an academic/philosophic discussion anyway ... to sad you did not enjoy it.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    15. Re:Eugen Fischer by nine-times · · Score: 1

      We've covered this. You're a crazy German who has somehow assumed that, because you once said something in Greek and your Greek friend didn't criticize you, the German pronunciation of any word in any dialect of any language is proper, and the only people in the world who disagree are English speakers who are somehow all dumber than you.

      Once we uncovered that much information, it stopped being worth my time to compose real responses. The fact that you don't believe linguists are capable of studying languages is just the last nail in the coffin. I've read your responses up until now, but I won't read any more. It's a waste of time. I'm guessing you're probably a 12 year-old or a mental case anyway.

    16. Re:Eugen Fischer by angel'o'sphere · · Score: 1

      Ah, sorry for the misunderstanding.
      I assumed you would be speaking or at least read greek and where interested in a civilized dispute about such stuff. I explain you my "thought process" you explain me yours ... we germans, and for that matter the greeks really like that.

      I did not realize that you are just a pretending asshole, the stuff you claim "I had written" in your last post I actually don't have.
      Example:
      the German pronunciation of any word in any dialect of any language is proper, and the only people in the world who disagree are English speakers who are somehow all dumber than you.

      So, just because you neither can read greek nor speak it, obviously, you have the right to insult, harass even someone whom's arguments you obviously can't follow?

      Wow ... but that is /. and I even had you marked green since years ... pft.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
  9. i knew that. by Anonymous Coward · · Score: 1

    This is a masterful, insightful and original joke that doubtlessly required a lot of effort and definitely has not already been posted in this thread.

  10. Re:Schizophrenia is not multiple personality disor by Will.Woodhull · · Score: 1
    "I have dissociative identity disorder, and so do I"

    Meh. That just isn't as funny as the old one.

    --
    Will
  11. Next deconstruction: autism. by macraig · · Score: 4, Insightful

    Next this needs to be done with what we call "autism". There's a reason it's called the "autistic spectrum"; it's a MUCH bigger but nebulous target than schizophrenia. There's so much symptomatic comorbidity that the diagnoses would be funny if the consequences weren't so depressing.

  12. Docs have long suspected as much. by sg_oneill · · Score: 2, Interesting

    One of the problems of Psychiatry is that because the brain has been bit of a black box to us for so long (We can see the input, we can see the output, but the gears and cogs inside remain a bit of a mystery) disorder classification has been mostly about symptomology rather than causes, most of the time. Docs have long suspected that "schizophrenia" was a collection of disorders with similar-ish results. This finding appears to confirm it.

    See also: ADHD and Autism.

    --
    Excuse the Unicode crap in my posts. That's an apostrophe, and slashdot is busted.
    1. Re:Docs have long suspected as much. by Anonymous Coward · · Score: 1

      traditionally psychiatrists have lied about how the condition worked. they sold us treatments for profits, including medication. each decade they revised the cause of it and the medical model of treatment. they used to think it was caused by too much blood in the brain, for example, and draining blood was a treatment for it.

      then after they discovered major tranquilizers from manufacturing petroleum byproducts and dyes after subsequently testing the chemicals on humans, they found they could "remove" the functionality of the brain with a chemical lobotomy. they then started to sell drugs to us. they revised the model a bit, claiming that drugs corrected chemical imbalances, a total falsehood. example: if you had too much dopamine you'd become psychotic or too little serotonin you'd be depressed. but research never backed that up, and tests show no correlation. in fact mice were recently bread w/ serotonin channels knocked out completely, while signs of depression did not increase. in reality the drugs work by knocking out pathways, blocking receptors of up to 99% of receptor sites for antipsychotics, erasing memories & impulses completely. antidepressants work by making serotonin / other pathways less useful, which results in inhibited nerve impulses and zombification (dead through serious drug injury, yet still living and walking and talking), removing emotion, focus, memories, and sensations, creating mentally illness. this damaging of a persons brain results in changes and new personalities, but does not treat the underlying problem . . Meanwhile those unlucky souls who got drugged never managed to recover naturally, and it's hard to describe how their lives and brain development were interrupted, .. many of them simply felt down or depressed, that happens, did nothing else to fix it, like it was a medical problem, then doctors tried to drug damage it out of them, interrupting nature and neurophysics from running it's course.

      many wonderfully collected articles are available for read @ http://www.madinamerica.com/..

      More @ http://www.oregonstatehospital.net/resources.html

      What I forsee for the future are treatments being made available that do not correct any problems but continue to mask the problem & cause other problems entirely. People will also be drugged into having a mental illness that never goes away, another cause for schizophrenia.

    2. Re:Docs have long suspected as much. by jbeach · · Score: 1

      Influenced by an earlier comment above, I originally read this as "Dogs have long suspected as much" : ) Perhaps they have. Perhaps they have.

      --
      The Invisible Hand of the Free Market is what punches workers in the nuts.
  13. Re:Schizophrenia is multiple diseases, really? by gargleblast · · Score: 2

    Well - no, and no. Recall that schizophrenia is a perception-of-reality disorder and has almost nothing to do with dissociative identity (a.k.a. multiple personality) disorder

  14. Re:Schizophrenia is not multiple personality disor by mod+prime · · Score: 1

    Since Greek is taken, maybe we could replace the clumsy literal PC English with Latin? "I have Schismentis and so do I?"

  15. 8 days a week by Anonymous Coward · · Score: 0

    I guess that is why some people are messed up 8 days from sunday. :)

  16. So a spectrum? by Anonymous Coward · · Score: 0

    Cool - a new 'spectrum' disorder! Schizo can be cool like those ADHD and Aspie kids!

  17. Old news by mescobal · · Score: 4, Informative

    Please stop repeating something like it is new. Since its origins the concept is called "the schizophrenias". We knew that 100 years before now: http://schizophreniabulletin.o...

    --
    La culpa no es del chancho...
    1. Re:Old news by Anonymous Coward · · Score: 0

      Please stop repeating something like it is new. Since its origins the concept is called "the schizophrenias". We knew that 100 years before now: http://schizophreniabulletin.o...

      Perhaps you and other people like you knew this, but the rest of us that are included in that 'We' did not.

    2. Re:Old news by Anonymous Coward · · Score: 0

      They didn't have DNA to back up the hypothesis 100 years ago. That also complicated the process of counting variations. I'm not claiming the current count (8) is accurate, as rare variants are almost by definition easily overlooked. But at least it's a much better supported hypothesis than we had in the past, when doctors only had symptoms.

      So, what we had was classical psychiatry, and this is new because it's evidence-based.

    3. Re:Old news by Anonymous Coward · · Score: 0

      This is very new and very significant scientific work. Too bad the summary didn't provide a sound bite that you recognized as novel. You couldn't be more of an idiot, and your post is the opposite of informative.

    4. Re:Old news by Anonymous Coward · · Score: 0

      I think they did give some new information, that is:

      genetic marker X is a good indicator of condition Y, while marker Z is an even better predictor of condition W.

      If they found genetic markers to associate with most forms of schizophrenias, then that is actually pretty big news.

  18. DNA? by Anonymous Coward · · Score: 1

    What if instead of sterilization we pass laws saying that if you knowingly and willingly pass defective genes on to your kid, you'll get prosecuted just as though you'd harmed them through abuse. For example, if a couple knew they were both carriers of the cystic fibrosis gene, they had a kid anyway, the kid had CF, and died at age 20, they would go to jail for murder.

    captcha = "condom"

  19. Flavor of the week by briancox2 · · Score: 2

    When you don't need to prove anything ... and it only needs to be "evidence based" ... a diagnosis can change as frequently as insurance billing requirements.

    --
    We should learn what we need to know about issues, before we decide what we need to feel about them.
  20. Schizos have multiple personalities by Anonymous Coward · · Score: 0

    Just like YOU, transsexual Frank N. Furter -> http://slashdot.org/~BarbaraHu... + http://slashdot.org/~tomhudson... + http://slashdot.org/~Barbara%2... ?? Guess you CAN actually, for once, play expert here on schizophrenics since it takes one to know one (or in your case, 3 registered slashdot accounts including how you stalk people by anonymous posts for years too freak).

    1. Re:Schizos have multiple personalities by Anonymous Coward · · Score: 0

      And in other news, APK is a hypocritical hypocrite whose hypocrisy towers over everything he says. That noise you hear? That's the sniggering of a thousand Slashdotters observing APK in his efforts to pass himself off as someone else.

  21. R O T F L M A O by Anonymous Coward · · Score: 0

    "Frank N Furter" (rocky horror picture show, right?) I read Barb/Tom's post history, he/she's really a transsexual nutjob.

    1. Re:R O T F L M A O by tepples · · Score: 1

      Are you sure it's not just two people in the same household whose personalities rub off on each other?

  22. Sets of mutations: necessary or sufficient by Anonymous Coward · · Score: 0

    There are thousands and thousands of different mutations that are known to cause intellectual disability (mental retardation) - and almost certainly millions and millions more yet to be discovered. Obviously intellectual disability is not a single gene disorder.

    But it's also been clear for a few decades that schizophrenia is not a single gene disorder. And in order to be diagnosed with schizophrenia you have to have fairly high levels of brain function. If you've got a mutation that disrupts your brain function so severely that you're never able to walk or talk and end up dying in early childhood then you're not going to be diagnosed with schizophrenia - even if the mutation disrupts genes involved in schizophrenia.

    Now, at some level these recent research results are guaranteed to be qualitatively correct - that there are different sub-types of schizophrenia caused by mutations in different sets of genes. And, of course, it follows that if a person has a particular sub-type of schizophrenia causes by a particular set of mutations then that particular set of mutations would also cause schizophrenia in other people. That is, the particular set of mutations would be a sufficient condition to have schizophrenia.

    The more subtle question is whether a particular set of mutations would be a necessary condition to have a particular sub-type of schizophrenia - and, based on a consideration of biological mechanisms, the answer is almost certainly "no" in the general case. Let's say you have some biological pathway/process that involves three genes - A, B, and C. And suppose that a set of minor mutations in all three genes results in schizophrenia. But what about more severe mutation in only two genes (A and B - but not C)? Surely, the combination of two mutations could also disrupt the same biological pathway/process as the combination of three mutations? Or what about a single very severe mutation in only gene A?

    What is the underlying biological mechanism where a biological pathway/process needs multiple mutations to be disrupted? You might propose a high level of redundancy but that only protects against loss of function but not gain of function mutations. If this research is correct there's still a lot that's missing.

    Along these lines, it's interesting that there's only a couple genes where mutations can cause schizophrenia with high penetrance - i.e. almost everyone who has the mutation gets schizophrenia. And, in that regards, it's interesting that there are individuals who are missing most of their brains due to genetic mutations but they still live mostly normal lives - just the mildest intellectual disability perhaps.

    So it will be interesting to see if this research pans out but my view is that the key issue is less likely to be that schizophrenia can only be caused by sets of genes and more that schizophrenia is such a high level disorder that environment plays a major role.

    1. Re:Sets of mutations: necessary or sufficient by CrashNBrn · · Score: 1

      I take it you find it interesting .

    2. Re:Sets of mutations: necessary or sufficient by Anonymous Coward · · Score: 0

      What is the underlying biological mechanism where a biological pathway/process needs multiple mutations to be disrupted? You might propose a high level of redundancy but that only protects against loss of function but not gain of function mutations. If this research is correct there's still a lot that's missing.

      There is some unclear assumption going on here; I think that schizophrenia somehow involves gain of function. There is no reason to assume so; it's just one of the many relatively likely ways of getting loss of function.

  23. "Barbara" (or is it really Tom) Hudson is... by Anonymous Coward · · Score: 0

    R O T F L M A O "Frank N. Furter"? Hey, you judge http://img3.wikia.nocookie.net...

    1. Re:"Barbara" (or is it really Tom) Hudson is... by Anonymous Coward · · Score: 0

      APK is a loser with nothing better to do than troll and stalk other people's posts. R O T F L M A O, he then hypocritically accuses others of the same behaviour.

      Old fool of a man, what recalcitrant rubbish are you going to throw next?

    2. Re:"Barbara" (or is it really Tom) Hudson is... by Anonymous Coward · · Score: 0

      He struck a nerve Barb. It's no rubbish. You're a real tranny. You've stalked him for years. You told others to do so with you by ac posts.

    3. Re:"Barbara" (or is it really Tom) Hudson is... by Anonymous Coward · · Score: 0

      Hahahahahahaha

  24. Does this mean genetic testing can daignose it? by mikeabbott420 · · Score: 1, Flamebait

    It might be very valuable for treatment if the condition didn't come as a mystery and a surprise. It also raises the question of testing in the early stages of fetal development and abortion being used by "carrier" couples to select for lower risk children. I honestly have no idea of what the ethical choices are there but I would lean towards multiple tries if it meant bringing a child to term that doesn't have such a high probability of suffering in its future.

    --
    This program was made possible by a grant from the Ultra-Humanite, and viewers like you.
  25. it is not, probably doesn't exist by globaljustin · · Score: 2, Interesting

    oh man...so is crazy genetic?

    no...but this study is from the University of Washington St. Louis wants to say it is...they analyzed data and this is what they conclude, from full text:

    Schizophrenia is a group of heritable disorders caused by a moderate number of separate genotypic networks associated with several distinct clinical syndromes

    That's what they say..."group of heritable disorders"...it reminds me of when I studied Mendell in HS science and fruit flies and hemophilia.

    It sounds fish as hell to me...psychology is great but it's so often wrong. ex: one year the DSM lists 'homosexuality' as an actual disorder...next year...not a disorder! magic!

    again...i actually love psychology...but it's just full of random theories from the 19th century that are floating around...so many disorders to describe very similar and overlapping symptoms...symptoms very often open to interpretation...

    I wanted to see if this passed the basic "correlation is causation" test...because this is just spreadsheets here these guys are looking at...they are re-analyzing data.

    From the full text:

    The 4,196 cases and 3,827 controls in the MGS study were combined to identify SNP sets. We had data of good quality on 696,788 SNPs on these cases and controls, and **from these we preselected 2,891 SNPs that had at least a loose association (p values,1.031022) with a global phenotype of schizophrenia (see the data supplement)**.

    Emphasis added. Honestly that's enough for me to want to see it for myself, the actual data on a computer screen, before I give this any credence.

    Obviously mental disorders exist. Just like anything it is related to our genetics and our environment and our choices...I would need to see alot of evidence before I believe TFA's assertions to the heritability.

    Examine this list of behavior (copied from wikipedia which quotes the DSM):

    According to the revised fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR), to be diagnosed with schizophrenia, three diagnostic criteria must be met:[10]

    Characteristic symptoms: Two or more of the following, each present for much of the time during a one-month period (or less, if symptoms remitted with treatment).

    - Delusions
    - Hallucinations
    - Disorganized speech, which is a manifestation of formal thought disorder
    - Grossly disorganized behavior (e.g. dressing inappropriately, crying frequently) or catatonic behavior
    - Negative symptoms: Blunted affect (lack or decline in emotional response), alogia (lack or decline in speech), or avolition (lack or decline in motivation)
    If the delusions are judged to be bizarre, or hallucinations consist of hearing one voice participating in a running commentary of the patient's actions or of hearing two or more voices conversing with each other, only that symptom is required above. The speech disorganization criterion is only met if it is severe enough to substantially impair communication.
    - Social or occupational dysfunction: For a significant portion of the time since the onset of the disturbance, one or more major areas of functioning such as work, interpersonal relations, or self-care, are markedly below the level achieved prior to the onset.
    - Significant duration: Continuous signs of the disturbance persist for at least six months. This six-month period must include at least one month of symptoms (or less, if symptoms remitted with treatment).

    I want to say that if you talk to a "good" psychiatrist or psychologist they will be able to explain how *they* personally in practice diagnose these different disorders and it may make sense. Furthermore, I'm convince psychology is a great area for scientific investigation.

    All that said, as I look at that list of behaviors, then I look at the data as presented, I can only conclude that "schizophrenia" is *probably* an obsolete distinction and this data is being erroneously interpreted.

    --
    Thank you Dave Raggett
    1. Re:it is not, probably doesn't exist by Risha · · Score: 4, Insightful

      Do you actually know anything about psychiatry, or are you just going by this particular article about a study that you think is iffy? Because it's not news that schizophrenia is at least partially hereditary, they've known that for decades. The same is true of bipolar disorder and major depressive disorder. The only debate is to what degree they are caused by hereditary versus environment. You can compare it to how diabetes runs in families, but in general can be triggered or not depending on your lifestyle. But some people will develop the disease even if they treat their body like a temple. This study has made the news because they're claiming to have identified the specific genes involved, not because there wasn't already general agreement that there were genes involved in predisposing someone to get schizophrenia.

    2. Re:it is not, probably doesn't exist by Dr.Dubious+DDQ · · Score: 1
      "That's what they say..."group of heritable disorders"...it reminds me of when I studied Mendell in HS science and fruit flies and hemophilia."

      "Heritable" doesn't mean exactly the same as "genetic".
      "Heritability" refers to how much of the variation of a trait in a population is due to genetics. The number of heads or legs a person has is most definitely "genetic", but not really "heritable" at all; if you meet someone with one leg or two heads,the reason for that is almost certainly NOT because of a mutation in some "number of heads/legs" gene they inherited.

      Writing that types of schizophrenia are "heritable" just reflects that there are genetic factors that influence how likely it is that someone will develop a variety of schizophrenia, not that schizophrenia is "caused" by genetics (nor necessarily that schizophrenia symptoms can't potentially be caused by environmental factors alone sometimes).

  26. citation note by globaljustin · · Score: 1

    those quotations are from page 2 and 3 of the full text of the study respectively

    --
    Thank you Dave Raggett
  27. There is no chemical imbalance.. by Anonymous Coward · · Score: 0

    Schizophrenia = They just hate you and want to control you.

  28. Bangs head against wall by John+Allsup · · Score: 2

    Bipolar Disorder, Psychosis and Schizophrenia for Dummies who know a little physics etc.

    Life is generally in a good position when it has potential (like gravitational potential in the case of high ground) and the capacity to use it in a controlled fashion. That means balancing in a position that would otherwise be considered an unstable equilibrium in the sense of dynamical systems theory. Our bodies are at their most efficient when well balanced (just watch a good dancer to see this in action) and our brains are at their best when similarly balanced. If something disturbs the equilibrium, this disturbance and the required correction can be used to understand the disturbance. This is how stimulation affects us.

    Now consider a simple example of a balancing physical object, but with no control mechanism: a spinning top. This has three states--spinning upright (when the gravitational potential is near its maximum), wobbling (when the gravitational potential is slightly lower, in which case it behaves erratically and gives up its energy randomly until...) finally we have the fallen over state. This is what medical people term depression. The simple solution is to get upright and balanced again, but this is hard in our modern overly complex society, and the result of trying to get up is often a lot of wobbling, which gets diagnosed as things like mania, psychosis and schizophrenia depending on how exactly this wobbling manifests itself. The key is to get balanced before you get pushed over, and that is hard when the medical mental health people seem to have the idea that you fix a wobbling spinning top by knocking it over and gluing it to the floor.

    Trying to understand mental health in a 'sum of the parts' way is just dumb, but it is the obsession of the medical fraternity, and is to the extent that it is politically very difficult to suggest otherwise. How our genetic code creates us is an approach that misses the point that without the environmental context in which that genetic code develops, it won't develop, so you need to understand the environment as well (and that means understanding the entire world in complete detail, which is rather a long way the other side of impossible).

    Viewed as an equilbrium seeking system, 'mental illnesses' like mania and schizophrenia are just seen as things like oscillations and resonant modes that are being excited by either an appropriate drive, or are resonating within the equilibrium seeking system. The biological stuff is just an implementation detail in much the way that transistors on a chip are implementation details of your python program that you are running that you can safely ignore in most cases. Medication is basically trying to solve a software problem by randomly pumping noise into the processor. A computer will crash instantly if you do this, but humans are rather more robust, and can survive for a long time in an unbalanced state. They are, however, rather unproductive in this state and won't tend to find life enjoyable. But they can survive for a long time, but can become desperate to get out of such states.

    --
    John_Chalisque
  29. they're not looking for a way to treat it by ihtoit · · Score: 1, Informative

    ...they're looking for a way to introduce and re-legitimise the term "sociopath" so it sews up the trainwreck that is the DSM.

    --
    Political debates have me rolling my eyes so much I think I got optical whiplash. I should sue. - Foamy The Squirrel
    1. Re:they're not looking for a way to treat it by Anonymous Coward · · Score: 0

      In all Soviet States, they do the same. Whether it is the U.S.A. or the U.S.S.R.

  30. Nutritional deficiencies! by Theovon · · Score: 1, Interesting

    Probably at least a few of those sub-disorders are actually nutritional deficiencies. We have this myth (perpetuated by MDs who have ZERO training in nutrition) that we don't have nutritional deficiencies in America. In fact, the American diet is horrible, and we all know it. B12 deficiencies are common (which is one of the reasons shots are often prescribed), as are deficiencies in magnesium, along with numerous other vitamins and minerals. Since the mid 90's, the FDA has mandated "enrichment" of foods, but the forms of the additives are NOT the biologically active forms, so some people have trouble processing them. For instance, MTHFR gene defects are common (my wife and I have different ones, and she has the really bad C677T defect), making folic acid (which is artificial) range from useless to poisonous to some people who need to take methylfolate instead. In fact, since the mid 90's a lot of people have reported declines in their health, which may be correlated with that FDA mandate (although without a more complete study, we have to assume this is anecdotal and COULD be correlated more strongly with something else).

    Anyhow, my point is that many psychological disorders, such as bipolarism, are associated with vitamin deficiencies. If you look at the symptoms lists of various B vitamin deficiencies, for instance, you'll see that it is already established what kinds of psychological effects can occur in cases of "extreme" deficiencies. If we can get past the idea that nobody in America can have extreme vitamin deficiencies (you can have plenty of some vitamin but still be anemic if you can't USE it in that form), then we can start treating mental disorders using carefully controlled diets and supplement schedules. I'm sure it won't work on everyone, but it would be insane to not try it in place of loading people up on antipsychotics because the "doctors" are mental hospitals have no fucking clue about nutrition.

    And just to reinforce, folic acid is basically poison to about 10% of humans. Different vegetables contain methylfolate and/or folinic acid, NOT folic acid. Defects in the genes that code enzymes that convert folinic acid and folic acid are more common than most food allergies, making this a serious problem!

    One interesting side-effect of this is the proliferation of the bad genes. People with homozygous C677T mutation have about a 30% conversion rate from folic acid to methylfolate. (Meanwhile the unconverted folic acid itself interferes with the methylation cycle.) If a woman gets pregnant and takes folic acid in large quantities (which is what doctors instruct), the fetus will take all of the methylfolate, and the mother will get very sick. Meanwhile the fetus will be allowed to develop when otherwise it would have naturally aborted due to an inability on its own to convert folinic acid that you get from food. As a result, we have more people born with this defect, while people in the FDA and the medical profession are too ignorant of the consequences to deal with them properly. Mind you, if they were to take more methylfolate, the viability of this defect would increase, but at least the mothers wouldn't get as sick.

  31. Not a single disease by Anonymous Coward · · Score: 0

    They're saying schizophrenia is married?

  32. WOW... This could be Nobel Prize worthy by Kevin+by+the+Beach · · Score: 1

    The analytics that went into this research have wide ranging application potential. This could be the tipping point for full exploitation of genetic markers in a wide range of medical/genetic diagnostics. It may not be as easy to build as say a single test like BRAC, but I could envision a series of grouped diagnostics markers that could be funneled into a matrix that would show the probability disease. Also, this is an excellent example of government (TAX) money well spent on research. Thank you NIH.

  33. Great news for U.S Big Pharma by Anonymous Coward · · Score: 0

    Because now they can sell no less than eight different pills to those unfortunate who are suffering from schizophrenia.

  34. It can be controller with medications by Anonymous Coward · · Score: 0

    It can be controlled however you need to work out with the doctors. It will take some time to get used to the medications and seeking help from the doctor for every appointment help narrow down the problem and find out the solution.

    Also, it is extremely important for family members to meet the doctors during the appointment where they can describe to the doctor about the patient's abnormal behavior (which the patient may not be aware of)

    I have schizoaffective disorder and i take the prescribed meds without changing unless directed by the doctor but the problem i see is having my wife to see the doctor to relate the behaviors that i made.

    For medications, i take sodium valprorate (a decade ago i had lithium carbonate that i had blood tests during the visit to the doctor) and a quite expensive though better medication called "olanzapine" with benzhexol to control the shaky hands on the nerves.

  35. environment, choices, and genetics by globaljustin · · Score: 1

    Because it's not news that schizophrenia is at least partially hereditary, they've known that for decades

    if it is such common knowledge, you should easily be able to point me to some sort of proof

    lets see it...show me proof

    also, after you paste a link to support your claim, I'd like for you to addess this as well: you're taking a complex situation, over-simplifying it, then telling me all the ways it becomes complex but just using your own rhetoric

    in one sense, i agree, everyone knows that your genes determine characteristics...but people like you ignore that it is **common knowledge** that many factors influence "who we are"...environment...personal choices,...just as salient, if not more, than genetics

    --
    Thank you Dave Raggett
    1. Re:environment, choices, and genetics by Risha · · Score: 1
      Ooookay? You're one of those people who like to demand "proof" in exhausting detail in any internet discussion, aren't you. Try plugging "schizophrenia hereditary" into any search engine, such as Google. Here are the first three results:

      As can be seen from the graph below, schizophrenia definitely has a very significant genetic component. Those who have a third degree relative with schizophrenia are twice as likely to develop schizophrenia as those in the general population. Those with a second degree relative have a several-fold higher incidence of schizophrenia than the general population, and first degree relatives have an incidence of schizophrenia an order of magnitude higher than the general populace.

      The causes of schizophrenia are not fully known. However, it appears that schizophrenia usually results from a complex interaction between genetic and environmental factors. Schizophrenia has a strong hereditary component. Individuals with a first-degree relative (parent or sibling) who has schizophrenia have a 10 percent chance of developing the disorder, as opposed to the 1 percent chance of the general population. But schizophrenia is only influenced by genetics, not determined by it. While schizophrenia runs in families, about 60% of schizophrenics have no family members with the disorder. Furthermore, individuals who are genetically predisposed to schizophrenia don’t always develop the disease, which shows that biology is not destiny.

      Unlike other genetic conditions such as Huntington's or cystic fibrosis, it is believed that no one single gene causes the disease by itself but rather that several genes are associated with an increased risk of schizophrenia. While schizophrenia occurs in one percent of the general population, having a history of family psychosis greatly increases the risk. Schizophrenia occurs at roughly ten percent of people who have a first-degree relative with the disorder, i.e., a parent or sibling. However, the highest risk occurs when an identical twin is diagnosed with schizophrenia. The unaffected twin has a roughly 50 percent chance of developing the disorder. The genetic component appears to extend beyond family environment. For example, children with a parent living with schizophrenia who were put up for early adoption still develop schizophrenia at a higher rate than the rest of the of the population.

      Further down the page, the US government weighs in:

      Scientists have long known that schizophrenia runs in families. The illness occurs in 1 percent of the general population, but it occurs in 10 percent of people who have a first-degree relative with the disorder, such as a parent, brother, or sister. People who have second-degree relatives (aunts, uncles, grandparents, or cousins) with the disease also develop schizophrenia more often than the general population. The risk is highest for an identical twin of a person with schizophrenia. He or she has a 40 to 65 percent chance of developing the disorder. We inherit our genes from both parents. Scientists believe several genes are associated with an increased risk of schizophrenia, but that no gene causes the disease by itself.16 In fact, recent research has found that people with schizophrenia tend to have higher rates of rare genetic mutations. These genetic differences involve hundreds of different genes and probably disrupt brain development.

      Some of those links include actual cites from scientific studies, by the way. I'm not going to bother locating physical copies of those journals and don't have a pubmed subscription, but you're welcome to look them up if you'd like.

  36. compare it to hemophilia by globaljustin · · Score: 1

    ok...compare "schizophrenia" as you are trying to explain it to something like hemophilia

    some disorder that is not based on perception of behavior

    so...hemophilia...the English royal family famously inbred so much that hemophilia became a problem genetically

    is hemophilia "heritable" or is it "caused" by genetics...show me in comparison to hemophilia how schizophrenia is "heritable" and "genetic"

    --
    Thank you Dave Raggett
  37. sources are not scientific & religious familie by globaljustin · · Score: 1

    you linked me to "schizophrenia.com"...which is sort of like linking me to "antivaxer.com" to as evidence vaccinations cause autism

    you even admit it yourself: "Some of those links include actual cites from scientific studies, by the way"

    how do you know that? how do you know those links cite scientific studies? did you see it yourself?

    so you looked at these articles, saw that they had actual research cited, but you chose **NOT** to copy/paste that information, instead, you chose to copy/paste information that *lacks* that information

    if you were trying to be honest in this discussion you would not have linked to those ridiculously questionable sources, and instead found the actual research (if it even exists)

    nih info...from the nih.gov page, we can see one of the fallacies of diagnosing disorders with symptoms of "hallucinations" and "strange speech"

    religious families...**of course** when the dad is a Pentacostal preacher the likelihood of his kids "hearing demons" skyrockets....***that is not genetic....it is ideological***...it is learned behavior, but even the best studies do not control for this

    i want to see how many of these cases are from religious families who believe that a deity speaks to them

    just saying that...just saying "God talks to me"...is essentially enough to get you diagnosed as schizophrenic according to the DSM!

    if your family members do ***anything*** you are more likely to do it, practically...that is not a genetic link at all

    --
    Thank you Dave Raggett
  38. Re:Look everyone: It's Frank N. Furter! by Anonymous Coward · · Score: 0

    Frank, please: You're the one that sliced off your furter (lol) and now you're pissed about it?

  39. Re:Frank N. Furter wasn't you dog confused? by Anonymous Coward · · Score: 0

    Hahahahahaha

  40. Re:Look everyone: It's Frank N. Furter! by Anonymous Coward · · Score: 0

    Hahahahahahahahaha

  41. Schizophreniacs have multiple personalities by Anonymous Coward · · Score: 0

    Just like YOU, Frank N. Furter! YOU have 3 on /. http://slashdot.org/~BarbaraHu... = http://slashdot.org/~tomhudson... + http://slashdot.org/~Barbara%2... so you seem to fit the bill (as you use each of them to mod yourself up and those who got the best of you down with).

  42. You have multiple personality disorder by Anonymous Coward · · Score: 0

    Schizophrenia, Frank http://slashdot.org/comments.p...

  43. Did they release the SNP data? by Anonymous Coward · · Score: 0

    I skimmed the paper and supplementary information, but didn't see a list of SNPs in their SNP sets, unlike the recent GWAS paper from the schiz working group. Did I just miss it, can it be obtained elsewhere, or did they really leave their main results out of the paper?

  44. genetics? nurture? by SylviaCaras · · Score: 1
  45. Keep in mind, it is wazzu we're talking about by Anonymous Coward · · Score: 0

    It's very likely a single disease and they just couged it.

  46. Who the HELL would want to do that to you? by Anonymous Coward · · Score: 0

    LMAO: A picture says a 1,000 words http://img3.wikia.nocookie.net...

    1. Re:Who the HELL would want to do that to you? by BarbaraHudson · · Score: 1

      Quite a few men apparently, judging from the ones who have either hit on me or tried to force themselves on me in the last few years.

      Of course, you're too busy mentally masturbating with your stupid HOSTS file to realize that the world has changed in the last few decades. Both your hosts file and your attitude towards the LGBT are woefully inadequate and obsolete, apk.

      It reminds me of the joke I heard as a kid.

      Little Johnny pulls down his pants and says "Ha ha, I have one of these and you don't."

      Little Suzie pulls up her skirt and says "Ha ha, my mommy says that with one of these I can get as many of those as I want!"

      Jealous much?

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    2. Re:Who the HELL would want to do that to you? by Anonymous Coward · · Score: 0

      You said you proved apk's points on hosts wrong. Where? You always run http://news.slashdot.org/comme... from them is what I see.

  47. BarbHudson's own stalking method quoted by Anonymous Coward · · Score: 0

    Telling others to stalk apk by ac posts as he/she does? I know not

    HOWTO: trolling the hosts file guy in one easy step The next time you see a post by him, just reply anonymously. And to really mess with his head, reply anonymously to your anonymous post, disagreeing with your first anon post (extra points if you claim in the second post that you're him - that REALLY sets him off) - by tomhudson (43916) barbara.hudson@ ... a - h u dson.com on Saturday April 16, 2011 @01:38PM (#35841122) Journal

    from http://slashdot.org/comments.p...

  48. I have undeniable scientific evidence by Anonymous Coward · · Score: 0

    Of /.'s own Frank N. Furter's schizophrenia/multiple personality disorder http://slashdot.org/~BarbaraHu... = http://slashdot.org/~tomhudson... = http://slashdot.org/~Barbara%2...

  49. So what are the 8 specific disorders? by jbeach · · Score: 1

    I couldn't find it in the article, and I'm not well versed enough in the science to pull it out of a quick scan of the doc.

    --
    The Invisible Hand of the Free Market is what punches workers in the nuts.
  50. And If Slapping One Label on Eight Is Not Enough.. by crunchygranola · · Score: 1

    We have "Schizo-Affective Disorder" in which we get to claim that the various "schizophrenias" and the various mood disorders are just one big unhappy diagnosis!

    Makes things easy for the diagnostician - just one diagnosis, and you can prescribe lithium and anti-psychotics to everyone. And then you can pile on more drugs to treat the side-effects from the drug combinations you started with. And then of course, there are the side-effects of the side-effect treating drugs. Eventually you can work your way up to one or two dozen drugs at once.

    Seriously - I have relatives that have suffered from this sort of diagnostic abuse.

    --
    Second class citizen of the New Gilded Age
  51. You're disordered and dangerous by Anonymous Coward · · Score: 0

    I think the main issue is that people associate scizophrenia with violent behaviour. It's actually fairly easy to give the assumption of an external voice in your head to anyone whom you subject to long term suggestion (it's what hacking a person is all about, also known as marketing). In my experience I've found most schizophrenics to be overly empathic which makes them highly suggestable, add to that a tendency to relate most things together (ex: rats are evil, cats kill, person is wearing a shirt with a rat on it, person said 'cat'! *auditory hallucination on the word cat* must kill person) it becomes reasonable to that person to believe God (existence surely must mean a single thing) has told them to kill. But it all comea down to morality at the end. One cannot blame murder on a state of being if they have the capability to talk, walk, dress up in the morning and eat. So to look at these "disorders" as a get out of responsibility free card is dangerous for all of us I believe, including to those who do have a schizophrenic mind but live a productive life.

  52. Bwaahahaha: bullshit by Anonymous Coward · · Score: 0

    They must be blind or stupid or you are lying (guessing the latter) Frank N. Furter.

  53. Hysteria by NewYork · · Score: 1
  54. Get to know the REAL 'BarbaraHudson' by Anonymous Coward · · Score: 0

    One of the 1st times "Barb" libeled me stating "APK is a know-nothing that's never worked in the industry" -> http://slashdot.org/comments.p... in 1 of her numerous sockpuppet fake accounts kept active @ the same time here she uses to upmod herself & downmod opponents she can't get the better of (everyone's onto your games, freak).

    Funny part is I've DONE FAR BETTER than ole' "cyclops Frank N. Furter" ever has shown in that exchange too http://slashdot.org/comments.p... , lol!

    ---

    Later, he/she kept a journal on me & libeled me even more but worse -> http://slashdot.org/journal/25...

    (Typical b.s. to *try* to 'put down' computer "geeks/nerds" saying "I live in a basement with my mommy" etc. when *ANYTHING BUT THAT* is true, considering I am a taxpaying homeowner!).

    ---

    * From the dates you can SEE she's kept this up unceasingly since early to mid 2010 no less, & that's only scratching the surface (there's far more).

    (Even TELLING OTHERS TO HARASS ME BY ANONYMOUS COWARD POSTS, calling me a "pedo" -> http://news.slashdot.org/comme... )

    He/She left in May 2012 after being exposed for ALL OF THAT, but came back with this NEW account of hers, & what started up again (I did *NOT* bother "shim" even once before that)?

    You guessed it (more harassment) -> http://tech.slashdot.org/comme...

    Where I challenged her for her usual CRAP she always runs from (to validly disprove my points on hosts, which she clearly, cannot):

    "I tore apart your stupid hosts file crapola." - by BarbaraHudson (3785311) on Tuesday August 19, 2014 @10:46AM (#47703255) Homepage

    Oh, really?

    Then why'd you run from disproving my points on them giving users added speed, security, reliability & more here too then -> http://tech.slashdot.org/comme...

    APK

    P.S.=> Barb/Tom (whatever, with multiple sockpuppets too http://slashdot.org/~BarbaraHu... = http://slashdot.org/~tomhudson... + http://slashdot.org/~Barbara%2... ) you've destroyed yourself yet again...

    ...apk

  55. BarbaraHudson: "Eat your words"... apk by Anonymous Coward · · Score: 0

    "His only "legend in his own mind" was that he claimed that "his" hosts file could completely secure a windows computer. " - by tomhudson (43916) on Saturday February 12, @11:19AM (#35186644) Homepage Journal FROM -> http://slashdot.org/comments.p... in the YEAR 2011 years ago no less

    I never claimed a HOSTS file can secure you completely... show me where I have? I want a quote, big talker... you'll never get it, because I never, EVER said that: HOSTS files are, however, a valuable layer of defense for the concept of "layered security".

    * You couldn't produce proof THEN, & you certainly can't now (vainly *trying* to put words in my mouth I NEVER ONCE SAID!)

    APK

    P.S.=> Still @ your LIES, you transsexual weirdo? Ok, asking it again now nearly 5 yrs. later now in response to your bullshit lies again here quoted:

    "APK - not only an expert on how the HOSTS file is the best way to secure your computer" - by BarbaraHudson (3785311) on Wednesday September 17, 2014 @07:06PM (#47932519) Homepage

    Under your NEW sockpuppet account too no less: SEE my challenge to you above - where've I ever said they completely secure you? I never have, liar...

    Of course, YOU ARE welcome to disprove my points on them after you said this lately too:

    "I tore apart your stupid hosts file crapola." - by BarbaraHudson (3785311) on Tuesday August 19, 2014 @10:46AM (#47703255) Homepage

    Oh, really?

    Then why'd you run from disproving my points on them giving users added speed, security, reliability & more here too then -> http://tech.slashdot.org/comme... ?

    ... apk

  56. BarbaraHudson: "Eat your words"... apk by Anonymous Coward · · Score: 0

    "His only "legend in his own mind" was that he claimed that "his" hosts file could completely secure a windows computer. " - by tomhudson (43916) on Saturday February 12, @11:19AM (#35186644) Homepage Journal FROM -> http://slashdot.org/comments.p... in the YEAR 2011 years ago no less

    I never claimed a HOSTS file can secure you completely... show me where I have? I want a quote, big talker... you'll never get it, because I never, EVER said that: HOSTS files are, however, a valuable layer of defense for the concept of "layered security".

    * You couldn't produce proof THEN, & you certainly can't now (vainly *trying* to put words in my mouth I NEVER ONCE SAID!)

    APK

    P.S.=> Still @ your LIES, you transsexual weirdo? Ok, asking it again now nearly 5 yrs. later now in response to your bullshit lies again here quoted:

    "APK - not only an expert on how the HOSTS file is the best way to secure your computer" - by BarbaraHudson (3785311) on Wednesday September 17, 2014 @07:06PM (#47932519) Homepage

    Under your NEW sockpuppet account too no less: SEE my challenge to you above - where've I ever said they completely secure you? I never have, liar...

    Of course, YOU ARE welcome to disprove my points on them after you said this lately too:

    "I tore apart your stupid hosts file crapola." - by BarbaraHudson (3785311) on Tuesday August 19, 2014 @10:46AM (#47703255) Homepage

    Oh, really?

    Then why'd you run from disproving my points on them giving users added speed, security, reliability & more here too then -> http://tech.slashdot.org/comme... ?

    ... apk

  57. Get to know the REAL 'BarbaraHudson' by Anonymous Coward · · Score: 0

    One of the 1st times "Barb" libeled me stating "APK is a know-nothing that's never worked in the industry" -> http://slashdot.org/comments.p... in 1 of her numerous sockpuppet fake accounts kept active @ the same time here she uses to upmod herself & downmod opponents she can't get the better of (everyone's onto your games, freak).

    Funny part is I've DONE FAR BETTER than ole' "cyclops Frank N. Furter" ever has shown in that exchange too http://slashdot.org/comments.p... , lol!

    ---

    Later, he/she kept a journal on me & libeled me even more but worse -> http://slashdot.org/journal/25...

    (Typical b.s. to *try* to 'put down' computer "geeks/nerds" saying "I live in a basement with my mommy" etc. when *ANYTHING BUT THAT* is true, considering I am a taxpaying homeowner!).

    ---

    * From the dates you can SEE she's kept this up unceasingly since early to mid 2010 no less, & that's only scratching the surface (there's far more).

    (Even TELLING OTHERS TO HARASS ME BY ANONYMOUS COWARD POSTS, calling me a "pedo" -> http://news.slashdot.org/comme... )

    He/She left in May 2012 after being exposed for ALL OF THAT, but came back with this NEW account of hers, & what started up again (I did *NOT* bother "shim" even once before that)?

    You guessed it (more harassment) -> http://tech.slashdot.org/comme...

    Where I challenged her for her usual CRAP she always runs from (to validly disprove my points on hosts, which she clearly, cannot):

    "I tore apart your stupid hosts file crapola." - by BarbaraHudson (3785311) on Tuesday August 19, 2014 @10:46AM (#47703255) Homepage

    Oh, really?

    Then why'd you run from disproving my points on them giving users added speed, security, reliability & more here too then -> http://tech.slashdot.org/comme...

    APK

    P.S.=> Barb/Tom (whatever, with multiple sockpuppets too http://slashdot.org/~BarbaraHu... = http://slashdot.org/~tomhudson... + http://slashdot.org/~Barbara%2... ) you've destroyed yourself yet again...

    ...apk