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Early Childhood Neglect Associated With Altered Brain Structure, ADHD

vinces99 writes "Under the rule of dictator Nicolae Ceausescu, thousands of Romanian children were placed in overcrowded orphanages with bleak conditions and minimal human contact, a legacy that continued even after the 1989 revolution. Only recently have research and public concern caused policy changes.

University of Washington research on children who began life in these institutions shows that early childhood neglect is associated with changes in brain structure. A paper published this month in Biological Psychiatry shows that children who spent their early years in these institutions have thinner brain tissue in cortical areas that correspond to impulse control and attention. "These differences suggest a way that the early care environment has dramatic and lasting effects for children's functioning," said lead author Katie McLaughlin, a UW assistant professor of psychology.

Since 2000, the Bucharest Early Intervention Project has worked to document and treat the children's health. McLaughlin joined the team about six years ago to focus on brain development. This study is among the first in any setting to document how social deprivation in early life affects the thickness of the cortex, the thin folded layer of gray matter that forms the outer layer of the brain. The study provides "very strong support" for a link between the early environment and ADHD, McLaughlin said.

48 of 87 comments (clear)

  1. Parallels exist in animals by BoRegardless · · Score: 1

    If you don't care for and train them early they will bite the hand that feeds them.

    1. Re:Parallels exist in animals by fustakrakich · · Score: 1

      We are animals. The parallels should be expected. Human nature is the same as all other nature.

      --
      “He’s not deformed, he’s just drunk!”
    2. Re:Parallels exist in animals by linuxrocks123 · · Score: 2

      Dude, that's no excuse. You still need to stop peeing on my lawn.

      --
      vi ~/.emacs # I'm probably going to Hell for this.
    3. Re:Parallels exist in animals by OakDragon · · Score: 1

      I think "nuclear family" does not mean what you think it does. But if I'm wrong, what is the alternative that you're thinking of?

    4. Re:Parallels exist in animals by fustakrakich · · Score: 1

      That's the dog (sorry 'bout that)... I'm out back helpin' the missus uh, *clean the pool*..

      --
      “He’s not deformed, he’s just drunk!”
    5. Re:Parallels exist in animals by linuxrocks123 · · Score: 1

      Human nature is the same as all other nature.

      I'll be more serious now: no, it's not. We fit the definition of animals, yes, but we're freaks of nature. We're smarter than all other animals we know of; our brains have more synapses than any other animal we know of; we have more complex societies than any other animal we know of; and, we've been able to harness more energy in directed ways than any other animals we know of (exhibited by electrical grids, cars, planes, and rockets that leave the fucking atmosphere and send objects into space). You wouldn't necessarily expect, say, a mouse or fish to have the same problems with emotional neglect that human children have if they aren't "shown love" but still have all their basic nutritional needs met. That's something that's going to fuck up humans much, much more than most other animals. It'll fuck up monkeys (someone did a morally reprehensible experiment, referred to elsewhere in this thread, that proved that). According to the GP, it'll fuck up dogs, too, which you might expect since they're relatively smart. But you can't go the other way. You can't say, "this level of social interaction is fine for my dog, so my kid'll be fine if I treat him like that, too". Because we're not like dogs. We're an extreme of nature. We're freaks.

      --
      vi ~/.emacs # I'm probably going to Hell for this.
  2. No need to go to Romania by Vinegar+Joe · · Score: 4, Insightful

    Just walk down any street in Chicago.......

    --
    "The average reporter we talk to is 27 years old......They literally know nothing." - Ben Rhodes
    1. Re:No need to go to Romania by germansausage · · Score: 1

      It's the baddest part of town........

    2. Re:No need to go to Romania by davester666 · · Score: 1

      Leroy Brown, is that you?

      --
      Sleep your way to a whiter smile...date a dentist!
    3. Re:No need to go to Romania by RandomSkratch · · Score: 1

      It runs parallel to Fake Street.

    4. Re:No need to go to Romania by AbrasiveCat · · Score: 1

      It's the baddest part of town........

      My name is Sue, how do you do.

  3. Thank facebook for the next generation of adhd by BarbaraHudson · · Score: 2, Interesting

    Too many parents are wasting more time on facebook and other "social media" sites. At least with TV, the parents could sit on the couch and have the kid on their lap, so there was some contact. Facebook and twitter are sowing the next generation of facebook and twitter users with low attention spans.

    --
    "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    1. Re:Thank facebook for the next generation of adhd by PPalmgren · · Score: 4, Interesting

      I'm as much of a lawn guarder as the next guy, but what? The ADHD spike really showed up in the 90's, well before this stuff existed or was commonplace. My stepmother's son has ADHD, born in the early 90's, and she's practically a luddite when it comes to technology.

      If anything, I think it would have more to do with a double income household. The uptick aligns more with the lack of stay-at-home parents than with technology. I'm not surprised children don't get the attention they need when mommy and daddy are working 8-5 and burned out trying to keep up with the Joneses.

    2. Re:Thank facebook for the next generation of adhd by LWATCDR · · Score: 1

      You left out divorce a swell which started to climb in the mid 70s.

      --
      See my blog http://ilovecookes.blogspot.com/ for light hearted technical information.
    3. Re:Thank facebook for the next generation of adhd by BarbaraHudson · · Score: 1
      People (both parents and kids) were spending (and fighting over) time on computers in the '90s. And not just for games - I saw one marriage destroyed by chat programs, who knows how many others it happened to.

      Then again, the vcr also did a lot of damage. I remember seeing people who would rent 6 movies Friday night, watch them, then rent 7 movies Saturday night, and watch them as well. The whole family was glued to the tube the whole weekend.

      Same with Atari 2600s and Nintendo.

      Some people can't walk away from "oh shiny!"

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    4. Re:Thank facebook for the next generation of adhd by BarbaraHudson · · Score: 1
      It's not an either-or situation. We've had a generation of ever-more complex devices more effectively competing for our attention, and the damage, like getting hit on the head repeatedly, is cumulative.

      This problem is now fed by sites that adapt their behavior to each individual to more effectively get and keep their attention. I didn't believe in internet addiction, but I'm now seeing so many people who can't even perform basic tasks like eating without constantly checking what's going on on facebook that I've had to change my mind.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
  4. Other possibilities? by jklovanc · · Score: 4, Insightful

    While human contact is very important in child development there might also be a least a couple or other contributing factors. Here are a few of possibilities;
    1. Lack of proper nutrition. If the body is spending all it's food surviving there is little left to grow. It is well known thet the brain takes a lot of nutrition to grow.
    2. Lack of exercise. If you don't use the motor parts of the brain they may not grow.
    3. Lack of stimulating toys.
    4. Lack of stimulating play.
    There may be more or it may be all of the above. The study does not isolate any of these factors so there is no way to know which one is important. This looks like yet another study to prove a theory rather than test the theory.

    1. Re:Other possibilities? by judoguy · · Score: 1
      I agree in general that these things might contribute, but I want to look at this through the lens of low income in the U.S.

      1. Lack of proper nutrition. If the body is spending all it's food surviving there is little left to grow. It is well known thet the brain takes a lot of nutrition to grow.

      Calories aren't the issue these days, it's crap carb calories. Low income = obese in America these days.

      2. Lack of exercise. If you don't use the motor parts of the brain they may not grow.

      I suppose, but running around is free, pretty much.

      3. Lack of stimulating toys.

      I'm old. When we didn't have any store bought toys, we played with sticks and tin cans and cardboard boxes and matches(!) when I was a kid in the 50s and early 60s. When bored enough, we'd dig holes in the sides of hills to make caves. I'm still amazed none of us died in a collapse.

      4. Lack of stimulating play.

      See the point above.

      I'm not a Luddite by any definition. I've been coding for over 30 years. Grew up going to Radio Shack for surplus parts before Tandy made it into a retail toy store. I grew up mostly as the only child of a single working mother. This whole issue is pretty complex.

      I just know it irritates the hell out of me to be in a restaurant and watch a small child trying hard, and failing, to compete with it's mother's phone for attention.

      --
      Peace is easy to achieve, just surrender. Liberty is much harder get/keep.
    2. Re:Other possibilities? by jklovanc · · Score: 1

      Calories aren't the issue these days, it's crap carb calories. Low income = obese in America these days.

      Calories are not proper nutrition. For that you need protein, vitamins and minerals.

      The rest shows how privileged you actually were. You were allowed to go outside and play with friends of your choice. You were allowed access to things like sticks, cans, matches and shovels. In these institutes most kids were kept indoors and forced to stay quiet and not cause issues. Your life was very different than institutional life.

      I just know it irritates the hell out of me to be in a restaurant and watch a small child trying hard, and failing, to compete with it's mother's phone for attention.

      There are two sides to every story. While you did see the child competing for attention you didn't see the child to exactly the same thing for the previous four hours. Sometime children need to learn to amuse themselves while parents do other things. For all you know the parent is setting up a play date for the child.

    3. Re:Other possibilities? by jklovanc · · Score: 1

      Care to cite any studies that support that statement? Here is a link to a list of studies and the conclusion is that the jury is still out on the effects of iron on ADHD.

    4. Re:Other possibilities? by jklovanc · · Score: 1

      Methinks thou dost protest too much. I said there may be other factors as well. I am just trying to point out that blaming the thinning of the brain on one factor is not scientifically supported by this study.

  5. ADHD by Anonymous Coward · · Score: 5, Funny

    Are people still getting ADHD ? Aren't they updating to AD4K these days.

  6. Not Surprising: supported by controlled experiment by cortex · · Score: 4, Interesting

    Greenough showed the effects of enriched and deprived environments on cortical connectivity and thickness in a series of studies. This is one of his early studies:

    Science. 1972 Jun 30;176(4042):1445-7. Rearing complexity affects branching of dendrites in the visual cortex of the rat. Volkmar FR, Greenough WT.

    "Higher-order dendritic branching is considerably greater in Golgistained neurons from the occipital cortex of rats reared in groups in a complex environment than in similar neurons of littermates reared individually in laboratory cages have intermediate amounts of branching, while lower-order branching did not appear to be affected by any rearing environment."

  7. Makes sense by EzInKy · · Score: 3, Insightful

    And I believe correlation will be found with the lack of child rearing and the forcing of both parents working on the populace. Began with Reagan as I recall, and most certainly coincides with the continuos concentration of wealth in the upper class in this country.

    --
    Time is what keeps everything from happening all at once.
    1. Re:Makes sense by DontLickJesus · · Score: 3, Insightful

      Forcing both parents to work likely isn't causal. The breakup of the family working all together at the same/related jobs is likely more specific. One can work and nurture at the same time, they rightfully go hand in hand. Teach your progeny what you know the way you learned it. It promotes learning and confidence in learning.

      --
      Where genius and insanity become confused true wisdom is found
    2. Re:Makes sense by EzInKy · · Score: 2, Interesting

      So you deny it was Reagan who drove the second parent from the home then? Name one major sociatal change in the last thirty years that enables the average person to support a family on one income. Hell, we can't even get a living minimum wage passed in this country. It's all about more profit for the profit mongers and nothing about the survival of the family. So for some it is the best of times, for others the worst of times.

      --
      Time is what keeps everything from happening all at once.
    3. Re:Makes sense by globaljustin · · Score: 1

      i don't think someone orchestrated the need for both parents to work as part of a way to alter the brain structure of a generation...

      but there is no denying that people with low impulse control make better consumers...

      --
      Thank you Dave Raggett
    4. Re:Makes sense by Tailhook · · Score: 4, Informative

      Reagan

      Here we are, discussing a story about the developmental damage measured in the brains of the victims of Ceausescu's communist hellhole, and this fucking freak starts bitching about Reagan, the one president in my lifetime that made a point of illuminating the plight of people subjected to that nightmare.

      In actual fact the ratio of working women has been steadily increasing since the end of WW2. Reagan's time in office didn't influence that trend one way or the other.

      But keep knock'n back that Daily KOS kool-aid. No sense in allowing reality to impede on that fucked up worldview.

      --
      Maw! Fire up the karma burner!
    5. Re:Makes sense by buddyglass · · Score: 1

      Day care, if done right, can be as stimulating as staying at home with mom. Even the average U.S. day care is light years away from an Eastern bloc orphanage.

    6. Re:Makes sense by LWATCDR · · Score: 2

      No you are wrong.
      http://www.dol.gov/oasam/progr...

      The rate of women joining the workforce has been more or less constant since 1948. The increase in the divorce rate, the pushing of women to have a career instead of staying home, the reduction of well paying manufacturing jobs, and many other issues has caused this.

      I know of a couple where the mother has the higher potential to earn and the father stays at home which is fine. The key is not that women must stay home but at least one parent should stay home during the early years of the childrens life.

      --
      See my blog http://ilovecookes.blogspot.com/ for light hearted technical information.
  8. And if the opposite was true? by nowsharing · · Score: 3, Interesting

    Imagine if the opposite was true; if complete neglect and institutionalization was good for kids. Now that would be a real finding.

  9. old article with different title by Anonymous Coward · · Score: 4, Insightful

    If you leave a child in a room, with all the nutrition and proper shelter that they will ever need, by themselves, they will grow up to be mentally retarded. This article brings nothing new to the table. It is common knowledge that without human contact they will have hindered learning abilities, such as language and social development, such as the Feral kid who grew up with wolves and ran around on all four legs and couldn't learn to speak properly.

    What we need are scientist who focus on positive outcomes, rather than the negative. What are the effects of creating interest for a child in lets say math, science, music, etc at a very early age? You may get a child prodigy, interest should be one of the highest priorities in school. Interest and potentiality are what create great minds, children have the highest potential versus a man who is in his 30's or even 20's, but first interest must be created before the potentiality can leap to higher levels. A child who has no interest in learning has no potential, but one who does can become the next Einstein.

    There are always going to be neglected children, an article on neglected children isn't going to help neglected children or bad parents. Children spend more time at school then they do at home (in terms of interaction and creating self identity). Schooling is where, if anything, disorders such as ADHD arise. The primary education system needs improvement, not parents, because nothing can actually be done about parenting, there will ALWAYS be bad parents, but there could always be GOOD TEACHERS who could improve their lives.

    What OP posted pretty much sums up what a bad scientist is, wasting time and resources on something that has little effect on helping the world

    1. Re:old article with different title by Anonymous Coward · · Score: 1
    2. Re:old article with different title by l0n3s0m3phr34k · · Score: 1

      I think it's partially because their mirror neural network never got properly "set up" . Mirror neurons are VERY important to being able to properly react and socialize...

  10. ancient news by swell · · Score: 3, Insightful

    Decades ago there was an experiment with monkeys deprived of maternal support to varying degrees. Some not allowed to touch or see the mother. Autopsies showed that the deprived monkeys had massive (and obvious to any observer) brain deficiencies. These monkeys were never able to adjust to social settings with others of their kind. Their behavior was obviously abnormal. My impression was that every moment of their life was stressful for them. Sorry I can't recall the source of the video I saw.

    This result would be the same for dogs, cats and humans. I can't comprehend why it would be news in the year 2014.

    --
    ...omphaloskepsis often...
    1. Re:ancient news by jc42 · · Score: 1

      Decades ago there was an experiment with monkeys deprived of maternal support to varying degrees. Some not allowed to touch or see the mother. Autopsies showed that the deprived monkeys had massive (and obvious to any observer) brain deficiencies. These monkeys were never able to adjust to social settings with others of their kind. Their behavior was obviously abnormal. My impression was that every moment of their life was stressful for them. Sorry I can't recall the source of the video I saw.

      This result would be the same for dogs, cats and humans. I can't comprehend why it would be news in the year 2014.

      Hmmm ... You seem to have missed the even more "interesting" followup studies. I was a grad student working with some of those reasearchers, so I heard a bit about it. They took their adult solo-raised monkeys, who were highly asocial, and caged them for a while with infant monkeys. After a few months, they took those individuals and put them in the "social" cages with established groups of their own species -- and they behaved like normal, socialized monkeys.

      So maybe we could try this with our "deprived" human children. Put them into a social setting (perhaps schools) with younger children, and watch their interactions. They aren't monkeys, of course, but we are all close relatives, so maybe it would work with them, and they'd become at least somewhat better-socialized humans after a while.

      Or maybe humans are hopeless. We don't really know until we do such experiments on ourselves. But we do seem to have a population of good test subjects, and the results couldn't be much worse than what we've been doing. Imprisoning such young adults in response to minor mischief would seem to be exactly the wrong thing to do, if those monkey experiments apply to our species, too.

      --
      Those who do study history are doomed to stand helplessly by while everyone else repeats it.
  11. See author Dr. Gabor Mate by Anonymous Coward · · Score: 1

    Not only is abuse a factor, but also basic critical factors missing from childhood such as emotionally stable adults. I've been studying this subject and working with kids (currently mentoring) for the last 5 years and it all fits, especially after meeting parents and observing how they treat and interact with their child. Check out author Gabor Mate and his books on stress, addiction, parenting, and ADHD. His lectures are all over youtube and his website is outstanding: drgabormate.com. I've handed out dozens of copies of his books to parents and it's made a difference in understanding not only ADHD, but the general mental health of children and what makes them behave as they do. If you are a parent I would urge you to check out this author, ideally before you kid reaches adolescence. Heads up!

    This link will hopefully inspire your interest:
    http://www.youtube.com/watch?v=UGmADfU5HGU

    This is a fairly core lecture:
    http://www.youtube.com/watch?v=HZNH7mvEgPA

    And of course the author:
    http://drgabormate.com/

  12. join the ECNA by turkeydance · · Score: 1

    the Early Childhood Neglect Association is a non-profit

    1. Re:join the ECNA by drinkypoo · · Score: 1

      shouldn't that be the care association? or is the point to promote neglect? that name is as bad as american cancer society

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
  13. Additional reading by stonedown · · Score: 2

    "The Boy Who Was Raised as a Dog" contains stories about children who went through trauma, and recovered to a degree one would not have thought possible. One of the stories is about the indoctrinated children who were released from Waco, before the structure burned. Another story is about a child which spent about a year (as I recall) caged like an animal. Though disturbing, it's a fascinating look at childhood development and a fresh way of looking at how best to care for traumatized children and help them to be able to heal as much as possible.

    "Born for Love: Why Empathy is Essential -- and Endangered" is about how empathy is "learned", and why it is so essential.

    Both books are by co-authors Dr. Bruce Perry and Maia Szalavitz. They are highly recommended for anyone working with traumatized children.

  14. CASA: I am for the Child by stonedown · · Score: 5, Informative

    When we are born, we have no choice what home we are born into, or who our parents are. We may be born into wealth or poverty. We may have parents who treat us with care and tenderness; or we may have parents who don't know how to care for a child, have drug addictions, are incarcerated, are violent, or are mentally unstable. Some children are loved and kissed, while other children are severely neglected, beaten, or abused sexually. This is the lottery we all played. Most of us won. Some children lost.

    Abused children are missing a part of their childhood. Where they should have received love, they received brutality or neglect. Because they missed out on a crucial part of their development, they are behind the other children. Children which have to be removed from their parents for their protection can sometimes be placed with family or a close friend. When this is not possible, they enter the foster care system.

    In the foster care system, there may be many people involved in the child's life: parents, other family or friends, social workers, attorneys, therapists, doctors, educators, foster parents or group home staff, and hopefully a Court-Appointed Special Advocate (CASA) or Guardian ad Litem (GAL).

    A CASA is a volunteer who is a constant adult presence in the child's life, which may be lacking other permanency. While social workers, group home staff, therapists, and doctors may work with many children, a CASA is assigned to a single child. The CASA meets with the child at least every other week, takes her out for activities or to eat, learns about her needs and circumstances, and uses this knowledge to advocate for her best interests.

    Please consider volunteering as a CASA.

    http://www.casaforchildren.org...

  15. Adoption by Charliemopps · · Score: 5, Interesting

    We adopted our son a few years ago. When you're going through the process you're required to take classes where they prepare you for this. Romanian and Russian orphanages are so horrific we specifically ruled out adopting from those countries. It's a tough choice but you have to weigh your families ability to deal with huge amounts of stress and the financial burden of years of therapy, drugs, etc...

    We adopted from Ethiopia, which is a country that's renowned how well they care for their orphans despite the poverty. I saw the care centers, and the people that ran them. They rival daycares here in the US and the workers hugged and cried with my son when he left. Even despite that, the lack of a true 1on1 relationship with a mother has had a significant impact on my son. With women especially, he fears they'll leave him. He acts out to get attention. His teachers need to do special 1on1 activities with him to reassure him. Give him special tasks, etc. It's tough but he's otherwise a great kid and definitely smarter than I was at that age. It's the biggest challenge I've ever had in my life. I couldn't imagine what the famillies of those Romanian children are going through. My hat is off to them.

    One of the first things they have you watch is this study from the 1950s where they gave monkeys a Fake wire mother that had milk and cloth mother that did not:
    https://www.youtube.com/watch?...

    Caution: it's emotionally disturbing to a lot of people.
    The monkey would rather starve on the cloth comforting mother than eat on the wire mother.

    1. Re:Adoption by Time+Ed · · Score: 2

      I adopted three from Ukraine. I can tell some stories about raising the products of East European orphanages.

      Chapeau to you sir. You and your wife are kind people. Good luck on your adventure.

    2. Re:Adoption by Morpeth · · Score: 2

      Just like to say, well done sir -- parenthood alone is hard work, let alone with any added issues. Hats off to you.

      --

      'The unexamined life is not worth living' - Socrates
  16. Did they account for nutrition and exercise? by neo-mkrey · · Score: 1

    Or lack thereof?

  17. not a repost by dingleberrie · · Score: 1

    So environment has a bigger influence that what we've measured in the Genome.
    If only we tackled the less expensive solutions first.

    http://science.slashdot.org/st...

    1. Re:not a repost by dingleberrie · · Score: 1

      Oops, this was a repost. I meant to post this comment in an alternate thread.
      http://science.slashdot.org/st...