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Testosterone Increasingly Being Used To Fight Aging In Men

An anonymous reader writes: In this time of advanced technology, our battle against aging isn't going well. Lifespan has been improved quite a bit through halting numerous diseases and improving nutrition, but medical science is struggling to slow the gradual wear and tear that builds up as we get older. Cutting edge treatment theories are all hellishly complex, so many men are turning to a solution that's been with us for 80 years: testosterone. Clinics are popping up around the U.S. that prescribe no actual medicine, but instead hand out testosterone and supplements. "In 2013, 14,000 kilograms of testosterone were sold in the United States. That might not sound like much, but a typical adult male has just 0.000000035 kilograms of testosterone floating around in his bloodstream. There is a lot of extra T in the hormonal composition of the country—and it only accounts for the legal sales."

John Hoberman, professor and author, calls this new medical model "client-centered libertarian medicine." He says, "Once upon a time, respectable society feared contamination by illegal and disreputable drugs that were consumed by social deviants. Now regulators are concerned about a growing demand for legal drugs that serve socially sanctioned goals such as productivity, physical attractiveness, and sexual viability. The 'threat' posed by such drugs originates in the very system of values that sanctions their use, and it is a paradox that has put regulators in an untenable position."

47 of 201 comments (clear)

  1. Is it low T? by RogueWarrior65 · · Score: 5, Funny

    No, it's low T&A.

    1. Re:Is it low T? by demonlapin · · Score: 4, Informative

      T&A = tits and ass; the implication is that men are seeking treatment because they aren't getting laid as much.

    2. Re:Is it low T? by dheltzel · · Score: 2

      Wait! You're saying Charlie's Angels had a plot?

      Off to watch some reruns to verify this . . . .

    3. Re:Is it low T? by RogueWarrior65 · · Score: 2

      Here's a musical number that explains it.
      https://www.youtube.com/watch?...

    4. Re:Is it low T? by Anonymous Coward · · Score: 2, Informative

      It should be pointed out that, past about age 65 - 70, men can get plenty of tail as there are many more women alive after then than men.

      Woo Hoo!

  2. "client-centered libertarian medicine" by Anonymous Coward · · Score: 2, Insightful

    AKA, under-regulated.

    1. Re: "client-centered libertarian medicine" by JaredOfEuropa · · Score: 2, Interesting

      That goes for cocaine as well, and any other substance abuse.

      I think anyone should have the right to snort, shoot or smoke anything they like, and that the government should curtail the use of drugs only in exceptional cases:
      - Use of the substance causes a clear danger to others (like drugs that turn you into an axe wielding maniac after 1 hit)
      - Use of the substance causes a clear danger to users (such as highly addictive drugs or drugs causing damage: marihuana / alcohol and minors)

      In such cases the government should step in, if:
      - The number of problem cases far outweighs the number of normally functioning users, and
      - The proposed controls are effective in reducing the number of problem cases, and
      - The effects of the proposed controls outweigh the undesired side effects of the controls (such as the impact on responsible users)

      Of course, one man's undesired side effects (such as regular pot smokers being jailed) are another man's bonus side effects.

      --
      If construction was anything like programming, an incorrectly fitted lock would bring down the entire building...
  3. Really, Slashdot? by Greyfox · · Score: 5, Insightful

    Tunning into an infomercial food suppliment quackery site, are we? This is a new low, even for slashdot. Did Dice put you up to this or are you just giving free advertising to any shit that comes along now?

    --

    I'm trying to teach myself to set people on fire with my mind... Is it hot in here?

    1. Re:Really, Slashdot? by Anonymous Coward · · Score: 2, Insightful

      According to the comments, Slashdot reaches a new low with every single article they post.

    2. Re:Really, Slashdot? by GrumpySteen · · Score: 2

      Dammit! Just look at this comment! Slashdot has reached a new low!

  4. Not medicine? by internerdj · · Score: 5, Insightful

    Estrogen given to a patient is medicine, what is different for testosterone? Is he making some sort of Paleo marketing ploy or does he mean that the product isn't going through the medical approval process?

    1. Re:Not medicine? by Enry · · Score: 2

      Because lady parts

    2. Re:Not medicine? by gstoddart · · Score: 5, Funny

      People get old, and there is no magic bullet to stop it.

      Well ... technically it doesn't need to be magic to stop you from getting old.

      --
      Lost at C:>. Found at C.
    3. Re:Not medicine? by BarbaraHudson · · Score: 3, Informative

      It only showed an increased breast cancer risk for those taking estrogen + progesterone. Estrogen-only treatment resulted in a reduction of breast cancer incidence.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    4. Re:Not medicine? by rogoshen1 · · Score: 2

      well to be honest, any old bullet with sufficient velocity stops aging in its tracks -- especially if applied directly to forehead.

  5. Article did not discuss downsides by gurps_npc · · Score: 4, Insightful
    They couldn't mention the downside of taking testerone?

    It decreases fertility, enlarges the prostate, and causes other issues.

    --
    excitingthingstodo.blogspot.com
    1. Re:Article did not discuss downsides by Dr+J.+keeps+the+nerd · · Score: 4, Funny

      Other side effects include aggression and being banned from sports competitions.

    2. Re:Article did not discuss downsides by thoriumbr · · Score: 4, Insightful

      I don't think aging people on their 70's will care much about fertility...

    3. Re:Article did not discuss downsides by rjstegbauer · · Score: 2

      ...as well as an increased risk of heart attack.

      http://abcnews.go.com/blogs/he...

      I'll pass, since I already have heart disease in my family history. You can choose otherwise.

    4. Re:Article did not discuss downsides by aliquis · · Score: 3, Insightful

      Some people argue dying at 75 is good.

      Some people would rather the physically and mentally fit in their 80-100 and then die at 100 rather than ill 80-120 and die at 120.

    5. Re:Article did not discuss downsides by NostalgiaForInfinity · · Score: 4, Insightful

      Low testosterone and high testosterone each correlate both with some desirable and some undesirable factors, and almost nothing can be said about causality.

      Your best bet is to exercise, eat better, and lose weight; that clearly has health benefits and will also naturally raise your testosterone levels.

    6. Re:Article did not discuss downsides by billewood · · Score: 3, Interesting

      There is considerable evidence that testosterone actually DECREASES male lifespan, perhaps by as much as 20 years. For example, from a very well controlled study on the lifespans of Korean eunichs: http://www.sciencedirect.com/s...: "The average lifespan of eunuchs was 70.0 ± 1.76 years, which was 14.4–19.1 years longer than the lifespan of non-castrated men of similar socio-economic status. Our study supports the idea that male sex hormones decrease the lifespan of men." I entirely support having the choice to take testosterone, for whatever reason one would like. I have a friend who's life has been quite improved by testosterone treatment, in fact. BUT taking T to help with unspecific effects of aging is a dangerous experiment and fad and people should be aware that there are likely to be some very serious and unforeseen consequences. I managed to talk my aging father out of this treatment, and as a consequence I just may be able to enjoy his company for years to come. Any doctor who suggests taking T to prolong lifespan is either critically misinformed or displaying severe lack of judgement, imo. And the author of that paper, who keeps referring to T as a magic wand? He is an idiot. I'm not a medical doctor but I am a PhD and I have done studies on the effects of sex hormones on animals. It's not clear why testosterone might decrease the lifespan of men, but one likely candidate is the fact that testosterone clearly decreases immune system function.

    7. Re:Article did not discuss downsides by LynnwoodRooster · · Score: 2, Funny

      The longer lives of the eunuchs wasn't from lower T - it was from not having 50 years of nagging wives...

      --
      Browsing at +1 - no ACs, I ignore their posts. So refreshing!
  6. in other words, manufactured ailment. by nimbius · · Score: 4, Insightful

    "client-centered libertarian medicine." is how assholes pronounce the words "snake oil" and It lives on the shelf with things like homeopathic remedies and juice cleansing. Testosterone, multi-inhaler asthma treatments, statin deficiency,and Circadian Dysrhythmia are all part of pharmaceutical corporations nose dive into profit with the concept of fear, forever and faith. Fear the disease, remember that once you have it you must always consume the product to relieve it, and finally never doubt your trust or faith in the product despite overwhelming evidence it may even be detrimental to your health.

    people become old as a part of human life. Testosterone does not radically alter that condition because becoming old is not a problem but a feature of life itself. In the United states as we inch inexorably closer to single payer healthcare its becoming increasingly evident to medical corporations that an alternate revenue stream will need to be secured. As an example, cigarette manufacturers diversified into food and alcohol; they realize relatively little revenue from cancer sticks at all.

    --
    Good people go to bed earlier.
    1. Re:in other words, manufactured ailment. by Anonymous Coward · · Score: 2, Insightful

      I do think this sounds a bit like snake oil, but I also agree that medicine needs to be deregulated, and treated like taxes: you can make your own decisions, but might also want an expert. These people are making their own decisions--so what if it's misguided? What do you care? And as the article states--why not collect data and see what's going on? Why rely on the FDA to make that evaluation? Because the FDA is never wrong?

      The problem is that, for every one of these examples, there's many many more of people trying to get basic medicines that they either can't get, or become costly to get (in terms of time or money, or both, because they're the same), because of overregulation. Do you really need a doctor or PA or NP for every prescription you get? No--I suspect that many Slashdot readers could make those decisions themselves, either when they start taking a med, or after an initial consultation, or could get meds from other providers. Has the war on drugs been successful? I think not.

      As I've grown older, I've come more and more to the opinion that if the government is trying to protect you from yourself, it's probably doing something it shouldn't be doing.

      I should go in for medical care because I need help, not because the government tells me I'm not in the capacity to make that decision for myself.

      Why do I really care what snake oil people take? If it makes them happy or fulfilled, let them do it. It's better than about a million other things they could be doing.

  7. Re:Well considering that many of us have low T by jellomizer · · Score: 5, Insightful

    I expect many people are getting diagnosed with Low T so they can get more bulked up at the gym faster.
    There is so much talk about an unrealistic body image for women. But the same thing is happening for men. We are expected to have 6 pack abs, Peck mussels that can dance, and arms thicker than your waist.
    We expect to look like a Greek Statue (while the ancient greeks made their statues, based on an exaggerated body image). While men should look more like that of Roman statues (based on actual body appearances)
    So we go to the doctor and explain that we have such problems and we get the prescription of T.

    Sure there are good reasons too, but I expect a lot of men are getting it where it isn't really needed.

    --
    If something is so important that you feel the need to post it on the internet... It probably isn't that important.
  8. Lift by kilfarsnar · · Score: 5, Insightful

    If you lift weights you can boost your testosterone naturally. And you'll get other benefits like more strength, increased bone density and better balance. You don't have to be Jack LaLanne (though he provided an excellent example). You just need to put your body under stress for 30 - 60 minutes 2 - 3 times a week; in a way that is safe for one's age, obviously.

    Regular exercise and a healthy diet can go a long way towards staying healthy and living longer. But we knew that already and still many of us do not do it. There's still the testosterone shot, I guess...

    --
    "What the American public doesn't know is what makes them the American public." -Ray Zalinsky (Tommy Boy)
    1. Re:Lift by Joey+Vegetables · · Score: 2

      I agree, but a man will benefit from those activities even more if his T starts out being near, or perhaps even slighly above, normal levels, with "normal" being defined not as the average today, which we know is much lower than in the past for various reasons, but the average from 30 years ago. I am not sure this is a bad thing as long as there is competent medical supervision. It's not for everyone; as others have pointed out, it can worsen heart problems, hypertension, aggression, etc. especially if done to excess. But many Americans are low due to medications, chemicals, age, etc., in addition to still-as-yet-unproven reasons. Proper diet, exercise, *and* supplementation may turn out to be the right solution for many people.

    2. Re:Lift by Anonymous Coward · · Score: 2, Informative

      Unfortunately, most people do not understand what it means to have low Testosterone. I suffer from low T and am familiar with this subject:

      1. Having low T means you have an organ somewhere not working. Primary: Testes. Secondary: Pituitary. Tertiary: Stress.
      2. Herbal supplements and working out do not raise Testosterone if you suffer from Primary/Secondary failure, because you cannot produce adequate amounts in the first place.
      3. Testosterone is not steroids. It is bio identical hormone. As someone pointed out in a previous response, if you were a body builder, you would be taking a steroid. Something way more potent.
      4. TRT, testosterone replacement therapy, simply puts a man WITHIN NORMAL RANGE of other men. Scales vary by lab, but a popular one is 300-1000. As a 35 year old man, comparing myself with the limited data available (fairly new science), i scored a 220. I'm suppose to be 400-600 atleast for my age. A man on TRT will simply receive (assuming he doesn't abuse it) will simply be dosed so that his TOTAL T falls within the avg range.

      Testosterone WORKS. Having only taken t-cypionate, i can tell you the difference for someone who suffers from low T (fatigue, memory loss, no libido, no morning erections, no real muscle gains in the gym) is night and day. Most guys just assume they are stressed out or unhappy when they suffer from these problems, like i myself did, but a body building friend of mine swore to me up and down that i had to have low T and i should get blood work done. 1 year after hearing him tell me the same thing, i went and got checked.... and he was right. I was below the minimum amount of acceptable testosterone. Not believing this, i got tested 3---- more times, at different clinics. I failed the test every time. So, i decided to 1 month of Test. I can tell you, that i use to 'feel normal' minus the libido, terrible sleep, and forgetfulness. By my 3rd day on T, i woke up with an erection which would have made my father proud, i actually wanted* to sleep with my girlfriend, and i was easily pushing more weight than i had been capable of in a long time. Testosterone is, bar none, THE CURRENCY in a man's body.

      Having been on both sides, i now REMEMBER what normal is. It's NOT normal to not want your girlfriend. Its NOT normal to have weak erections or no morning wood (when your 35), and its NOT normal to have crappy sleep and wake up every few hours. Increasing my T to 'regular' levels comparable to other 35 year olds SOLVED all of these issues for the duration that i was on it. So please, if you're like me, and really have a need for it.... PLEASE, ignore all the crap you hear about it, and try it.

  9. Not entirely untenable by ItsJustAPseudonym · · Score: 2

    ...it is a paradox that has put regulators in an untenable position.

    Maybe not entirely. Here's a recent article about fake supplements: http://www.washingtonpost.com/...

    Regulation, apparently, has its part to play.

  10. Re:Well considering that many of us have low T by Anonymous Coward · · Score: 3, Interesting

    Sorry but no. First off, body builders aren't taking testosterone. There are much better steroids out there (or "gear" in musclehead parlance). Nobody who wants to bulk up would ever take testosterone. It's just not worth it in terms of expense, difficulty of acquisition and frequency of dosing.

    Secondly, you should look into the three major global testosterone studies. There have been 3 studies since the 1980's. The results: Testosterone levels in the developed world (but not emerging markets) have plunged almost 30% over the past few decades.

    That means you. (Assuming you're of the XY persuasion).

    You can blame a combination of water recycling (and women on the pill), ubiquitous soy in our foods, statin drugs, plastic water bottles and more.

    The irrefutable evidence is that testosterone levels in America, Europe and Japan have tanked. The question that policy makers and physicians are asking is, "should we care?"

    I think probably, yes. But to each his own.

  11. Side effects may include death by John+Newman · · Score: 3, Interesting

    Testosterone supplementation in men with low T levels appears to have the unfortunate side effect of death.

    There is a growing literature on the potential dangers of testosterone supplementation. Not enough yet to say it's as clearly a bad idea as female HRT, but for sure it isn't something men should run out and do without a careful and personalized discussion with a knowledgeable (actual) doctor.

    In general I think it's safe to say that the "take extra of the hormones that go down with age in some people" theory of fighting aging is pretty thoroughly discredited by now. Thyroid hormone, growth hormone, testosterone, estrogen, etc. - the science is clear this is not how you fight aging. In general, more likely to hasten death than prevent it.

    1. Re:Side effects may include death by Joey+Vegetables · · Score: 2

      This is well understood, and means that testosterone therapy is contraindicated in people with, predisposed to, or having a family history of these problems. That would include me. It also means it may be risky for others. I am considering it anyway, for the simple reason that I'd rather be maximally healthy for 20 more years than to live 40 in my current condition, which is influenced by low testosterone (it is not absurdly low, just a little, but still affects my life in countless ways, nearly all of them negative).

    2. Re:Side effects may include death by judoguy · · Score: 2

      Not enough yet to say it's as clearly a bad idea as female HRT, but for sure it isn't something men should run out and do without a careful and personalized discussion with a knowledgeable (actual) doctor.

      Even endocrinologists, unfortunately, are not immune to cant and insurance industry pressure.

      Too many of them just run insurance driven diabetes shops and ignore actual science in adherence to "conventional practice", i.e., not what works, but what is defensible in court.

      --
      Peace is easy to achieve, just surrender. Liberty is much harder get/keep.
  12. testosterone problems by Anonymous Coward · · Score: 4, Insightful

    As a physician, I have seen the growth of the testosterone industry over the past decade. This has been pushed by direct to consumer advertising by big Pharma, which fails to adequately inform the target population of the significant risks. Co-opted endocrinologists have been paid to create a new syndrome called "andropause" which can be treated with testosterone. We learned the risks of estrogen in post menopausal women only after many years, and we now are set to repeat the same story with cardiovascular disease, prostate problems, and stroke in men. Why can't we just age gracefully?

    http://www.drugwatch.com/testosterone/heart-attack/
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901445/

    1. Re:testosterone problems by blue9steel · · Score: 2

      Why can't we just age gracefully?

      Why would we want that? Natural != Good I happen to like vaccinations, antibiotics, pain killers and other marvels of modern medicine, why don't you?

  13. change your diet and exercise instead by NostalgiaForInfinity · · Score: 4, Insightful

    Low testosterone, aging, and loss of lean muscle mass, fat gain, obesity, diabetes, heart disease, low libido all correlate. Because testosterone supplementation improves some of these problems somewhat, people have concluded that they might be caused by low testosterone. But they are clearly caused simply by bad diet and lack of exercise, and you're likely going to improve your overall health much more by exercising and eating better. Exercise and improvements in diet will also naturally increase your testosterone levels.

    Once you start taking testosterone, you usually end up dependent on it for life. That means not just applying it every day, it means more frequent checkups, monitoring for side effects, and pretty tough questions when you start getting prostate problems and cancer (which you will, sooner or later).

    Trying to fix what are just bad lifestyle choices in most men (lack of exercise, too much sitting, bad diet) with medicine (statins, testosterone, etc.) also puts an enormous strain on our medical system and is one of the reasons the US spends so much money on health care: the cost of testosterone replacement is usually several hundred dollars a month for the drug alone, plus even more money for the extra monitoring and tests. Insurance may currently cover that, but don't bet on it in the future. And even if it covers it, you still end up with co-pays, frequent trips to the doctor, and potential complications and additional drugs to deal with side effects.

    (Of course, some small percentage of men really do have abnormally low or absent testosterone due to actual disease, and for those, supplementation makes sense.)

  14. Re:Do the Division by Anonymous Coward · · Score: 3, Informative

    No, it absolutely does not mean that. What you said would have made sense if 14,000 kilograms were all used in one instant not throughout the whole year.

    The typical blood content cannot be used to establish dosage without the half life, which in this case is only 2-4 hours. So you would need quite a few doses of 0.000000035 kg per day just to keep the level around that value. In practice, typical dosages that lead to normal blood levels are on the order of 100-200mg per week. With that in mind 14,000kg equates to year-long treatments for 1.5-3 million men.

  15. Re:Well considering that many of us have low T by pr0nbot · · Score: 2

    Dancing peck mussels was how I discovered I was allergic to seafood :(

  16. Re:Well considering that many of us have low T by linear+a · · Score: 5, Interesting

    Curious about those studies. Were they age-controlled or survey of the general (ageing) population?

  17. Re:Not affecting life expectancy in a positive way by Beyond_GoodandEvil · · Score: 2

    While this might seem like it reduces aging, US is 45th or 46th in life expectancy globally. Other countries are not using these treatments, and men live an extra 10-12 years in some of them
    Ugg, So much wrong info. 1st US is 36th in life expectancy, 2nd our neighbors to the north, Canada lives 2.7 years longer and they're #11. So as you can see there's a not really a difference in living 3 more years yet those 3 years span 25 other countries. Taking these treatments isn't going to kill you that much faster.

    --
    I laughed at the weak who considered themselves good because they lacked claws.
  18. Re: by hawkinspeter · · Score: 4, Funny

    You can burn your fingers if you're not very good with a lighter.

    --
    You're a temporary arrangement of matter sliding towards oblivion in a cold, uncaring universe
  19. Narrowing that down, if 10% become mass murderers by raymorris · · Score: 2

    > In such cases the government should step in, if:
    > - The number of problem cases far outweighs the number of normally functioning users, and

    I wonder if we can make this a bit more specific and clear. You said "the number of problem cases", but I wonder if you meant "the direct and indirect effects of problem cases". Here's why I say that:

    Suppose that smoking Z has limited negative effects on 90% of users. Perhaps most just get lazy and unmotivated. However, 10% of users commit mass murder. Going strictly by the words you wrote, substance Z shouldn't be regulated - most users don't become dangerous. The people who are not dangerous ARE however killed by the 10% who go postal. That would be a problem.

  20. Re: by Immerman · · Score: 2, Informative

    There have been several studies now that suggest that marijuana use, particularly heavy use, among minors (prior to early twenties, while the brain is still developing ) cause a drop in intelligence and significant structural brain changes of unknown impact.

    Still wouldn't be my go-to drug to reference for "clear dangers" - the only clear dangers that spring to mind are are those shared by alcohol - the perceived safety, combined the proclivity for doing stupid things under the influence. Granted alcohol is a lot more likely to get you into life-threatening situations, but some puritan parents might consider getting laid to be similarly dangerous to their precious indoctrinated babies.

    Beyond that there's always the old saw the "Marijuana is hazardous to your health - it can cause your ass to be thrown in jail" - which is in fact probably by far the greatest danger of the drug, and a very real danger at that.

    --
    --- Most topics have many sides worth arguing, allow me to take one opposite you.
  21. Re:Well considering that many of us have low T by GrumpySteen · · Score: 2

    I work a job that expects me to be in the office 6-7 days a week for 12+ hours. ...
    I am moody, have low energy, have low focus, am easily distracted, am losing motivation, have low libido, am tired, am stressed, and am starting to feel run down.

    Stress causes testosterone levels to drop. Get a job that doesn't require working 72-84 hours a week and your testosterone levels will probably go back to normal on their own without adding to your risk of strokes, heart attacks and blood clots.

  22. Re:Not affecting life expectancy in a positive way by sexconker · · Score: 2

    List_of_countries_by_life_expectancy on wikipedia

    Flawed list using flawed data that, even if you trusted it, doesn't properly account for differences in the tracking of infant mortality.

  23. Re:Fight Aging? by BarbaraHudson · · Score: 2

    Why do humans feel the need to fight every issue that arises?

    Too much testosterone?

    --
    "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.