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Researchers Uncover the Genetic Roots Behind Rare Vibration Allergy (vice.com)

derekmead writes: A team of National Health Institute researchers has for the first time uncovered the genetic roots of one of the strangest allergies: vibrations. The vibration allergy, which is just as it sounds, may be quite rare, but understanding it more completely may yield important insights into the fundamental malfunctioning of immune cells in the presence of allergens. The group's findings are published in the New England Journal of Medicine. In addition to being uncommon, the vibration allergy is not very dangerous. In most cases, the allergic response is limited to hives—the pale, prickly rash most often associated with allergic and autoimmune reactions. Other less-common symptoms include headaches, blurry vision, fatigue, and flushing. The triggering vibrations are everyday things: jogging, jackhammering, riding a motorcycle, towel drying. Symptoms appear within a few minutes of exposure and are gone usually within an hour.

83 comments

  1. Wifi allergy by waynemcdougall · · Score: 2

    And what if I have a vibration allergy in the 2.4 GHz range?

    --
    Recycle PCs and build a wireless community network www.hillsborough.org.nz
    1. Re:Wifi allergy by brian.stinar · · Score: 1

      Then you must live in the great capital city of my state, Santa Fe.

    2. Re:Wifi allergy by Anonymous Coward · · Score: 0

      And what if I have a vibration allergy in the 2.4 GHz range?

      Sorry, cracking up too hard to provide an answer.

      Don't worry though, hysterical laughing is probably just an allergic reaction to bullshit hypothetical questions.

    3. Re:Wifi allergy by Applehu+Akbar · · Score: 1

      "Then you must live in the great capital city of my state, Santa Fe. [engadget.com]"

      So Saul's crazy brother is not an aberration there?

    4. Re:Wifi allergy by Anonymous Coward · · Score: 0

      That would be an interesting idea but "electromagnetic sensitivity" has already been disproven (as in proven to be completely phycological)... so there's nothing to explain.

    5. Re: Wifi allergy by Anonymous Coward · · Score: 0

      I'm allergic to the sound vibrations caused by laughter, you insensitive clod!

    6. Re:Wifi allergy by antdude · · Score: 1

      Or both? :P

      --
      Ant(Dude) @ Quality Foraged Links (AQFL.net) & The Ant Farm (antfarm.ma.cx / antfarm.home.dhs.org).
    7. Re:Wifi allergy by penguinoid · · Score: 1

      And what if I have a vibration allergy in the 2.4 GHz range?

      Then you're allergic to LED lights, but only when they're on a wireless router.

      --
      Don't waste your vote! Vote for whoever you want, unless you live in a swing state it won't matter anyways
    8. Re:Wifi allergy by Anonymous Coward · · Score: 0

      Then you would have a histamine reaction to microwaves that would be trivial to test for...

    9. Re:Wifi allergy by ITRambo · · Score: 2

      It's logical to presume that our universe did not create a demon with horns that tortures "bad" people for all of eternity at the whim of a bearded white man sitting on a throne atop a cloud, with his spirit on one side and his son on the other side. The universe is far greater than that, whether it was created by the word of God that gave birth to the universe, or an initial vibration that set off a massive expansion and standing waves that led to the formation of matter when things cooled down.

    10. Re:Wifi allergy by Anonymous Coward · · Score: 1

      And what if I have a vibration allergy in the 2.4 GHz range?

      Then you're allergic to LED lights, but only when they're on a wireless router.

      I'm getting a bit tired of all the jokes regarding wifi allergy. They are lame and don't deal with the issue. If the issue exist, then you are making fun of handicapped people. If it doesn't exist, then you make fun of mentally ill people. On top of that, it's not even funny when people keep telling the same "joke".

      Medical books aren't flawless. Take for instance phantom pain, as in pain in amputated arms or legs. This was described as lack of nerve ping reply and can appear when nerve pathways are cut. Misshapen people born without fully developed limbs were viewed as mental disturbed when complaining about pain and it was a sign of envy towards "normal" people. At some point one doctor started researching the books for the source experiment for this info and failed to locate it. He then used a brain scanner to see activity in the pain center. While the pain was easy to detect, it turned out that it was impossible to tell from the scan if the limb was present at birth or not. In other words pain is lack of ping reply, but it doesn't have to have ever worked in order to trigger. They don't yell highly about all the people they labeled as mentally ill due to complaining about pain through the years.

      A more "fun" case was a doctor who treats people with back problems. They then to ask about sex and he answered what the books states. At some point he noticed the the single source for "correct" position for minimizing strain on the back turned out to be a single doctor, who assumed the answer without tests. After this discovery he decided to test this with a scientific approach. He made test subjects do it in all sorts of positions and measured strain in each case for each gender. It turned out that the previously recommended spoon was actually the worst of the normal positions. Instead the correct is woman on back, man standing. While not critical, it is still an untested assumption, which made it into the books and used as patient recommendations.

      Cel phones have been tested and it turns out that the brain activity increases up to half an hour after using one. The effect of this is unknown, other than falling asleep is harder than if you didn't use the phone just before trying.

      Slashdot had the story not long ago about the brain communicating with itself using a magnetic field. Comments (for once) actually stated that this test result for once gave wifi allergy some credibility and such comments wasn't even voted as funny or trolling.

      Wifi allergy (or whatever we should call it) is problematic to test. For starters, there are billions on the line for the industry, if not more than that. This naturally results in a risk of bribery. There are also golddiggers, who naturally fails to show effects when tested. Whoever is behind the test can also have personal or political reasons for wanting a certain result.
      All this combined as well as lack of tests, which can be repeated by other labs with the same result makes me question how much we actually know about this issue. I wish and hope for wifi to be harmless, but I would prefer to get a trustworthy proof of that.

      And yeah you can be allergic to LED. It's called prone to seizures, which can be triggered by flashing lights. It can also trigger migraine, which (unlike what some people believe) isn't just a headache. In fact it is much worse and always attack the very same spot on the head, indicating a physical defect related to that area. Bright light or high frequency light can also trigger migraine. Unlike wifi allergy, migraine is a proven medical condition where doctors can test if a patient has an attack right now.

      Still some doctors not working with migraine have no problem stating that the condition doesn't exist. Reminds me of a GP doctor, who told me food allergy doesn't exist and he knew that better than the allergy department at the hospital, who issued the paper stating that I do have food allergy. This is yet another reason not to trust just a single doctor or a single test result unless you have reason to trust the doctor.

    11. Re:Wifi allergy by Gilgaron · · Score: 1

      You can't be allergic to flashing lights, an allergy is an immune response. You could be sensitive to flashing lights, and maybe WiFi, but the latter certainly hasn't be shown in any testing I've seen. It seems like pedantry but if you're trying to engage with scientists and medical professionals and they scoff at the idea of allergies to certain things it would be because there isn't a mechanism for that phenomena to interact with the immune system. Things can be unintuitive: iodine is too small to cross link antibodies but people can be allergic. How? It binds to epitopes on your cells that are large enough to cross link antibodies and changes their conformation to something sensitive people's immune systems target as foreign.

    12. Re:Wifi allergy by Anonymous Coward · · Score: 0

      Nice link.

    13. Re:Wifi allergy by myowntrueself · · Score: 1

      It's logical to presume that our universe did not create a demon with horns that tortures "bad" people for all of eternity at the whim of a bearded white man sitting on a throne atop a cloud, with his spirit on one side and his son on the other side. The universe is far greater than that, whether it was created by the word of God that gave birth to the universe, or an initial vibration that set off a massive expansion and standing waves that led to the formation of matter when things cooled down.

      Also the modern Christian 'devil' is just that; very modern and did not exist in Judaism nor even European paganism (eg Norse, Celt, Germanic, Greek nor Roman).

      --
      In the free world the media isn't government run; the government is media run.
    14. Re:Wifi allergy by Anonymous Coward · · Score: 0

      That ain't nuthin'. Hell, I whack off at 2.4 GHz.

    15. Re:Wifi allergy by JumperCable · · Score: 1

      If it was true, then it would be testable. To date, no person claiming WiFi allergies have been able to tell you when wifi is on or off.

    16. Re:Wifi allergy by TylerJWhit · · Score: 0

      Logical? By definition, logic uses a systematic form of of thought to validate or invalidate an idea. You've provided no 'logic' to your conclusion. You've only made a definitive declaration. Your premise and your conclusion are the same, and therefore circular. There was no systematic process you went through to derive the conclusion you got. Every statement you've made is a questionable premise.

  2. The triggering vibrations are everyday things by turkeydance · · Score: 1

    vibrating

  3. Re:The democrats are the servants of the devil by Anonymous Coward · · Score: 0

    The devil is their master

  4. Turn up the bass by Anonymous Coward · · Score: 0

    1) Turn up the bass
    2) develop skin herpes
    3) ????
    4) Profit, probably.

  5. Re:The democrats are the servants of the devil by Anonymous Coward · · Score: 0

    She won't serve the people. She won't serve the companies. She won't serve their campaign donors. She will serve THE DEVIL.

  6. Re:The democrats are the servants of the devil by Anonymous Coward · · Score: 0

    Trump will deliver us from Clinton. He will forgive our Obama.

  7. wife by Anonymous Coward · · Score: 0

    Maybe thats why my wife complains about a headache after she uses he vibrator???

    1. Re:wife by reboot246 · · Score: 1

      Maybe with you, but with the rest of us she never complains!

    2. Re:wife by Anonymous Coward · · Score: 0

      Maybe it's easier to shove the vibrator up your asses than the OP's.

  8. I know someone who has the allergy by Anonymous Coward · · Score: 1

    Your mom. She gets all flush and blurry eyed when I vibrate her.

  9. CLINTON WANTS TO ENSLAVE OUR CHILDREN by Anonymous Coward · · Score: 0

    Black and white. We will die for the chinese.

  10. Re:The democrats are the servants of the devil by Anonymous Coward · · Score: 0

    Voting republican is the only chance to come into heaven. The only one.

  11. Re:The democrats are the servants of the devil by Anonymous Coward · · Score: 0

    THE DEVIL SPIRIT clouds the voter's eyes. Only the just see the truth.

  12. Re:The democrats are the servants of the devil by Anonymous Coward · · Score: 0

    The democrats will ruin the land of the free.

  13. Re:The democrats are the servants of the devil by Anonymous Coward · · Score: 0

    Sanders was sent by him PERSONALLY.

  14. Everyday things by GrumpySteen · · Score: 4, Funny

    The triggering vibrations are everyday things: ... jackhammering

    Really?

    1. Re:Everyday things by Anonymous Coward · · Score: 0

      I get like this from operating 2 cycle engines, sometimes badly. I still won't use a weed whacker, and my chainsaw is electric.

    2. Re:Everyday things by Anonymous Coward · · Score: 0

      jackhammering

      Ur mom.

    3. Re:Everyday things by Anonymous Coward · · Score: 0

      My name is Jack Hammer, you insensitive clod!

    4. Re:Everyday things by Venerable+Vegetable · · Score: 1

      It's part of my morning routine. Wake up, take a shower, eat a sandwich, do some jackhammering, go to work. Isn't his how everyone does it?

    5. Re:Everyday things by Anonymous Coward · · Score: 1

      The triggering vibrations are everyday things: ... jackhammering

      Really?

      Sometimes vibrator just doesn't cut it.

    6. Re:Everyday things by Anonymous Coward · · Score: 1

      I usually jackhammer-off before I shower.

  15. wtf is "towel drying" by Anonymous Coward · · Score: 1

    and why does it involve vibration... i just hang shit up and thermodynamics happens, how is everyone else drying there towels?

    1. Re:wtf is "towel drying" by I'm+New+Around+Here · · Score: 1

      I think it means using a towel to dry something. Such as their skin.

      --
      If you think I voted for Trump because of this post, you're wrong. I voted for Dr. Jill Stein of the Green Party. Again.
    2. Re:wtf is "towel drying" by Rain2 · · Score: 1

      Thatsthejoke.jpg

    3. Re:wtf is "towel drying" by I'm+New+Around+Here · · Score: 1

      Oh, I see. I just thought it was a really clueless AC. :^)

      --
      If you think I voted for Trump because of this post, you're wrong. I voted for Dr. Jill Stein of the Green Party. Again.
  16. jackhammering? by AndyKron · · Score: 2

    Jackhammering is an every day thing? Maybe to some people I suppose.

    1. Re:jackhammering? by Anonymous Coward · · Score: 0

      Every day in the sense of a 'common, mundane phenomena', as opposed to a vibration allergy that is only triggered by very particular types of vibrations at specific frequencies or intensities.

      It's a poor choice of words, but understandable none-the-less.

    2. Re:jackhammering? by del_diablo · · Score: 1

      You don't have to live in that large of a city before you might encounter jackhammers 3-4 weeks a year, because some construction work is being done somewhere you pass by.
      Occasions include replacing pavement, redigging underground cables, replacing lamp posts, and more.

  17. No Winter Dwellers by Anonymous Coward · · Score: 0

    So if they started shivering they'd break out in a rash? Interesting.

  18. THEY PRAY TO THE DEVIL EVERY NIGHT by Anonymous Coward · · Score: 0

    He is their ruler.

  19. Re:The democrats are the servants of the devil by reboot246 · · Score: 1

    So she's self-serving? I can believe that about any politician.

  20. Could that allergy be Cholinergic Urticaria? by Anonymous Coward · · Score: 0

    Could the vibrations cause enough heat to trigger it? Perhaps mislead the body into thinking it's next to a heat source.

    Just wondering because i suffer from another rare allergy, from cold allergy, started around age 5 or 6 on my face cheeks.

    Perhaps these allergies may all have something in common or strong similarities at the genetic level?

  21. Very interesting that this is a real thing. by Anonymous Coward · · Score: 0

    I guess it is too early in the age of this thread to get any useful comments other than jokes about vibrators and normal political trolls.. no surprise.

    I think they might be onto something here. I have type 1 diabetes and have had for 20 years. I had a lot of bizarre allergies as a kid to normal things that no one else was allergic to and a lot of allergic responses that seemed to have no explanation. I tell that story to share this:

    I came down with type 1 when I was in my mid 20s, and have been involved in research since being diagnosed and have learned a lot about the disease and how it comes about for some people (myself included) In most cases where type 1's develop the disease and are not born with it, the auto-immunity has been brewing for about a decade before the diagnosis happens. (You can be pre-type 1 diabetic and still not have symptoms. You can be down to a 2% functional islet mass in the pancreas and still not have high blood sugar.) Point is that the disfunction that brings about type 1 starts as much as 10 years or so before the functional islet mass population goes below 2% and full blown type 1 diabetes comes about.

    I remember when I was about 12, I had this odd skin reaction that was like just random inflammation, and I could never figure out what caused it. It used to really freak people out.. I could sometimes just take my fingernail and scratch lightly on my arm and write words and about 20 to 30 minutes later the word would swell up and turn red and look like someone had carved a word on me with a knife and then 20 minutes after that it was gone. Odd, random inflammation. Scratching can be a kind of low vibration so this seems to have something to it. Anything that lets us understand what is going on with the adaptive immune system sheds some light on the development of type 1 and other related diseases that share the same pathways (this includes diseases like Rheumatoid Arthritis, Ulcerative Colitis, Multiple Sclerosis, Shogrens syndrome and scleroderma to name a few.) The more we know about what is happening the more we can find genes and immune cells and chemicals and proteins that are part of the process that are players in the disease and will help bring out better ways of diagnosing the disease and treating and eventually curing it.

    So in summary I think that this sheds some light on my experiences with auto-immune disease.

    1. Re: Very interesting that this is a real thing. by Anonymous Coward · · Score: 0

      Best post in thread is by AC :/

    2. Re:Very interesting that this is a real thing. by Major+Blud · · Score: 1

      In most cases where type 1's develop the disease and are not born with it

      I'm Type 1 as well. Although we weren't "born with it", we were most certainly born with the genetic marker that made us susceptible to it (I'm sure you know this).

      I had this odd skin reaction that was like just random inflammation

      Maybe that odd skin reaction is what triggered the auto-immune response that attacked your islet cells? I know correlation-and-causation and all of that, but it makes you wonder about a lot of things that you could catch that would trigger that response (the Coxsackie virus has been implicated, but is somewhat inconclusive).

      Just remember, we're only 10 years away from cure, and have been for over 30 years now ;-)

      --
      If you post as Anonymous Coward, don't expect a reply.
    3. Re: Very interesting that this is a real thing. by Anonymous Coward · · Score: 0

      A huge amount of diabetes is self inflicted consuming way too much sugar in your diet is probably much more likely them a extremely rare vibration allergy.

    4. Re: Very interesting that this is a real thing. by Anonymous Coward · · Score: 0

      Learn the difference between type I and type II diabetes so you can troll better next time.

    5. Re:Very interesting that this is a real thing. by Anonymous Coward · · Score: 0

      In most cases where type 1's develop the disease and are not born with it

      I'm Type 1 as well. Although we weren't "born with it", we were most certainly born with the genetic marker that made us susceptible to it (I'm sure you know this).

      I had this odd skin reaction that was like just random inflammation

      Maybe that odd skin reaction is what triggered the auto-immune response that attacked your islet cells? I know correlation-and-causation and all of that, but it makes you wonder about a lot of things that you could catch that would trigger that response (the Coxsackie virus has been implicated, but is somewhat inconclusive).

      Just remember, we're only 10 years away from cure, and have been for over 30 years now ;-)

      Actually we are closer to a cure for type 1 from a few different angles of research and I was told a cure was 5 years away when I was diagnosed 20 years ago. (They were talking about a stem cell cure, but stem cells do not address the auto-immune part, after a time all of the grafted cells will just be re-currant disease.) What I believe the key to a type 1 cure is adjuvant therapy that re-programs the adaptive immune system. This is done in much the same way as a vaccination works but is much more specific.. essentially you immunize yourself against the errant immune cells and helper T-cells kill the auto-immune cells in mass.. This is already being done in human patients. Also there are drugs under investigation (this would be off label drugs that are already approved by the FDA) like Verapamil, that reduces the expression of a gene called TIXNIP, which would essentially cause the immune system not to be able to attack the beta cells, due to not being able to see them. Both interventions are in the phase 2 human trial stage at this point. There are also starting to be gene therapies that could have an effect both in specific tissues and systemically . This is the best time in history so far to be diabetic.. though that can be said about any time in the future.. Insulin pumps will get better, this will keep us alive until a practical cure comes about.. until that time all I can say is , eat healthy, exercise and stay in shape, stay healthy and hold out until one of a few hundred practical cures pan out.

  22. TFA forgot one other source by Anonymous Coward · · Score: 0

    Motorboating.

  23. Advancing knowledge by LunaticTippy · · Score: 1

    I love stuff like this. Finding a scientific explanation for something that sounds like baloney. All the bogus gluten and electricity allergies have made me very skeptical about things like this, but this is fascinating. It sort of rubs me wrong, it doesn't make sense to me that vibration could induce an allergic reaction, but I cannot deny evidence like this.

    --
    Man, you really need that seminar!
    1. Re:Advancing knowledge by Anonymous Coward · · Score: 0

      I love stuff like this. Finding a scientific explanation for something that sounds like baloney. All the bogus gluten and electricity allergies have made me very skeptical about things like this, but this is fascinating. It sort of rubs me wrong, it doesn't make sense to me that vibration could induce an allergic reaction, but I cannot deny evidence like this.

      I posted above about type 1 diabetes and skin allergies.

      You may not understand if you have never experienced it, but ever have an itch that the more you scratched it the more it itched? Same kind of thing. Other than allergic reactions mosquito bites can be like that.. the more you mess with it the more it bothers you. It all starts with an irritant and the cells degranulate and you end up with inflammatory cytokines in the skin and you get the hives and or flushing.. You want to see what this is like in a controlled fashion? Take a 500 milligram Niacin pill (Nicotinic acid, not Niacinamide which is your "No-Flush niacin) and wait about 20 minutes.. you will get skin flushing starting at your head and going down your body for about a half hour.. same kind of reaction. It is a very real thing, the reaction is caused by an inflammatory chemical called Prostaglandin D2 or PGD2 for short. read about it here:

      Fascinating none the less and it is a real thing and another puzzle piece in allergies and medical conditions and autoimmunity.

    2. Re:Advancing knowledge by Obfuscant · · Score: 1
      I have vibration allergy, you insensitive clod.

      I don't get hives, my response to the allergen is to have a palsy. This, of course, creates a positive feedback loop -- until I explode.

      Yes, much like Kenny, those bastards with jackhammers kill me every time. Good thing I'm a time lord.

  24. Don't worry, baby by Anonymous Coward · · Score: 0

    They're just allergy hives! I'm allergic to repetitive motions. Honest!

  25. Re:Not an allergy by blue+trane · · Score: 1

    Say that when you have annoying physical symptoms associated with exposure to an allergen.

  26. Wind Turbine Illness? by xxxJonBoyxxx · · Score: 1

    Could this be behind "wind turbine illness" a lot of people now complain about?

  27. tl;dr by Hylandr · · Score: 1

    In short, they literally allergic to physical exertion.

    Reminds me of my Ex...

    --
    ~ People that think they are better than anyone else for any reason are the cause of all the strife in the world.
  28. Yes, an allergy by Anonymous Coward · · Score: 1

    Jesus christ being sensitive to vibrations is not an allergy.

    But having a histamine response to vibration is the very definition of an allergy.

    The fuck is wrong with people.

    Your comment makes me wonder the same thing.

  29. Re:Not an allergy by arth1 · · Score: 1

    Jesus christ being sensitive to vibrations is not an allergy.

    I didn't even know he was sensitive.

    The fuck is wrong with people.

    Ok, thanks for the diagnosis. At least there are pills for that.

  30. I have this by Anonymous Coward · · Score: 0

    ..and I can't jog as a result. Jogging more than a few blocks triggers one of the itchiest sensations I have ever felt throughout my leg muscles. It takes an hour to dissipate.

  31. That's dermatographic urticaria. by denzacar · · Score: 1

    I remember when I was about 12, I had this odd skin reaction that was like just random inflammation, and I could never figure out what caused it. It used to really freak people out.. I could sometimes just take my fingernail and scratch lightly on my arm and write words and about 20 to 30 minutes later the word would swell up and turn red and look like someone had carved a word on me with a knife and then 20 minutes after that it was gone.

    That's dermatographic urticaria. It's relatively common - about 5% of people have it.
    https://en.wikipedia.org/wiki/...

    --
    Mit der Dummheit kämpfen Götter selbst vergebens
  32. Is this why mountain biking made my arms itch? by PeterM+from+Berkeley · · Score: 1

    It never bothered me much, frankly, but my arms would itch every time I would mountain bike going over washboarded paths. Usually I was hanging on too hard to the handlebars to really pay much attention to it.....

    --PM

  33. sex... by Anonymous Coward · · Score: 0

    must be tough to have sex,....

  34. Oh, crap. Brace for impact by ThatsNotPudding · · Score: 1

    "You know what else vibrates? RADIO WAVES!!!"

  35. Not entirely ridiculous, but not an “allergy by Theovon · · Score: 1

    I have “touch urticaria.” Especially at night when I like in bed, the pressure against my skin causes histamine production. I’ve had this checked out, and while my histamine levels are high, my IgE levels are completely normal, so this is NOT an allergic reaction. Something else is putting excessive histamine into my system. A dietician suggested that it could be intestinal flora generating histamine, and a dietary change may help, so I’ve been working on that. But at this point, I have to take Allegra every night so I can get to sleep without itching and scratching for hours. (Fexodenadine is very weak, but it's the only antihistamine I can stand — all others zombify me the next day, including Claritin and Zyrtec.)

  36. Damnit by wkwilley2 · · Score: 1

    My hands swell and get itchy when I use a weedeater for longer than 30 minutes at a time.

    I know this isn't web MD, but I think i finally have an allergy.....shit.

    --
    Have you ever fallen asleep at the keybhanusdiog?
  37. Hypo-allergenic vibrators? by Anonymous Coward · · Score: 0

    These things don't work as advertised for these people then...

  38. I think I have this! by pisces22 · · Score: 1

    This makes me sound like I browse WebMD and then believe that I have every malady out there but I've been diagnosed with Exercise-Induced Anaphylaxis and Urticaria (http://www.aafp.org/afp/2001/1015/p1367.html). However, my doctor indicated that even vibrations can set it off. I once broke out in hives while just standing at a concert. The boom-boom-boom of the beats over the course of a couple of hours was, apparently, enough to bring out the hives. Shit sucks. I have to take Zyrtec to exercise, take a flight, go to a concert, or use my jackhammer.

    1. Re:I think I have this! by mcswell · · Score: 1

      I had exercise-induced urticaria, but it was the result of an actual food allergy. I would occasionally break out in hives after a long run, or when taking a hot shower after a run. I went to a dermatologist (or maybe it was an allergist, I forget now) and had the 40-pin skin test. It showed a pronounced allergy to beef and tomatoes. I stopped eating beef and tomatoes before a run (so long Philly cheese steaks...), and haven't had urticaria in over ten years, despite still running distances and taking hot showers.

      Disclaimer: I've never used a jackhammer.