Slashdot Mirror


New Research Suggests the Appendix Has a Purpose After All (qz.com)

The appendix is an organ thought to have gone the way of our wisdom teeth and body hair: At one point we all needed them, now people can get by just fine without them. However, it turns out, at least the appendix has some purpose in the body. From a report: Scientists, though, have never been certain what the appendix used to do -- and if it is still, in fact, useless. On Jan. 9, a team of researchers led by scientists at Midwestern University Arizona College of Osteopathic Medicine published a review study proposing an answer: the appendix is a secondary immune function that both catalyzes immune cell responses and floods your gut with beneficial bacteria when they've been depleted. And it still plays that role, in a limited fashion, in human body function."We can function okay without it, but the appendix does provide some degree of immunity and beneficial bacteria,â Heather Smith, an anatomist and lead author of the paper said.

24 of 133 comments (clear)

  1. "News" by ledow · · Score: 5, Informative

    Not news.

    The appendix has MANY subtle jobs rather than one obvious one, that's why you can do without it.

    I've been telling people for 20+ years after reading it online that the appendix is PARTLY a store of stomach bacteria etc. to help reseed the stomach in the case of it being flushed during illness.

    People with appendices recover better from a bout of stomach flu and are less likely to get knock-on infections that those without. It's been in the medical literature for decades, at least, and been on this site at least twice I'm sure.

    It's also not the appendix's only job.

    This is not "news" at all.

    1. Re:"News" by ledow · · Score: 4, Informative

      Yep. Wikipedia has citations going back to 1989 for that.

    2. Re:"News" by jellomizer · · Score: 2

      Well like a lot of science News it probably is a bad summary of the newest findings. The big thing that happened recently in science is the realization on how integral to our health those bacterias are. So the appendix benefits from this finding shows that it is far more helpful than before.

      --
      If something is so important that you feel the need to post it on the internet... It probably isn't that important.
    3. Re:"News" by Impy+the+Impiuos+Imp · · Score: 3, Funny

      Your chiro would probably tell you the appendix problem was due to sublaxations and recommended some kind of feely-doo. You would now be dead without the butcher.

      --
      (-1: Post disagrees with my already-settled worldview) is not a valid mod option.
    4. Re:"News" by lord_mike · · Score: 2

      People WITHOUT appendices are also much LESS likely to get Ulcerative Colitis, but much MORE likely to get its cousin, Crohns Disease... which also suggests there is something immune related to the organ. If you get an appendectomy before the age of 20, you are less likely to get either Inflammatory Bowel Disease!!

      http://www.badgut.org/informat...

    5. Re:"News" by T.E.D. · · Score: 3, Funny

      Yep. Wikipedia has citations going back to 1989 for that.

      Sadly most people never notice those citations, because they are down in the Appendix.

  2. Shocking. by Anonymous Coward · · Score: 2, Interesting

    You mean to tell me that something attached to other organs, that has blood vessels, that has metabolizing and reproducing cells, that has multiple cell types, that has nerve endings, actually has a purpose? Gee whiz next thing you'll be telling me that the tailbone has no function and we'd be A-OK if instead of something hitting your tailbone it hits the end of your spinal cord directly instead.

  3. How is this news? by argStyopa · · Score: 5, Informative

    I've read about this role for the appendix for at least 5 years? At LEAST.

    Here's an early article I found on the subject https://blogs.scientificameric... - and if SciAm had it in 2012, it had to be relatively established information, they're not anywhere near cutting-edge reportage.

    And here's a Discover magazine thing saying the same thing in 2008: http://discovermagazine.com/20...

    --
    -Styopa
  4. always read the appendix by turkeydance · · Score: 4, Funny

    for useful info.

  5. Re:Mystery solved by ledow · · Score: 5, Interesting

    Because DNA of anything tends to carry legacies and evolve from previous similar things rather than just invent random stuff. Re-use is a large factor of DNA and it's complexity masks a lot of differences. That's why most diseases are NOT "just one dodgy gene".

    This is why two testicles look similar to two ovaries, and why there's two of each, and why both sexes have pubic hair and anus in the same place, and why the female pelvis - though differing dimensions - isn't fucking octagonal or something.

    And your gender is determined not in some magical early moment but quite late in foetal development, and not cast in stone as you're also surrounded by female hormones until birth.

    More strange is why certain birds have such vastly different coloured/shaped/sized male/females.

  6. White Blood Cells, part of the Immune System by CrashNBrn · · Score: 5, Informative
    The Appendix: Slimy But Not Worthless (2006)

    The appendix is a slimy, dead-end sac that hangs between the small and large intestines. It's about a half inch in diameter and three inches long. As quickly as 11 weeks after conception, the appendix starts making endocrine cells for the developing fetus. Endocrine cells secrete useful chemicals, such as hormones, and the appendix endocrine cells secrete amines and peptide hormones that help with biological checks and balances as the fetus grows.

    After birth, the appendix mainly helps the body stave off disease by serving as a lymphoid organ. Lymphoid organs, with their lymphoid tissue, make white blood cells and antibodies.

    The appendix, by virtue of its lymphoid tissue, is part of a complicated chain that makes B lymphocytes (one variety of white blood cell) and a class of antibodies known as immunoglobulin A antibodies. The appendix also produces certain chemicals that help direct the white blood cells to the parts of the body where they are needed the most.

    The dirty gut is a good training ground for young white blood cells. The appendix, with its sac routinely collecting and expelling foodstuffs, exposes the white blood cells to myriad bacteria, viruses and drugs passing through the gastrointestinal tract. This way, the white blood cells learn to fight potentially deadly bacteria, such as E.coli.

    The appendix's contribution to the body's white blood cell and antibody production reaches its peak when you are about 20 or 30 years old, then production falls off sharply. By age 60, the appendix serves very little active purpose. ...

    Emphasis mIne.

  7. Re:Mystery solved by fahrbot-bot · · Score: 4, Funny

    ... as you're also surrounded by female hormones until birth.

    And the you get married and have a daughter and you're surrounded yet again until... the day... you die.

    [ P.S. I wouldn't have it any other way... ]

    --
    It must have been something you assimilated. . . .
  8. Re:Mystery solved by JoeMerritt · · Score: 2

    Because women have nipples, and the additional genetic code required to completely remove nipples from males gives no survival benefit.

  9. Re:Mystery solved by aliquis · · Score: 2

    So when is the decision of XX vs XY chromosomes made?

  10. Re:American scientists catch up, after decades by Hognoxious · · Score: 2

    That's nothing! Recently slashdot discovered that the moon was created by something banging into the Earth!

    --
    Confucius say, "Find worm in apple - bad. Find half a worm - worse."
  11. Re:Mystery solved by HornWumpus · · Score: 2

    Everybody has two rows of vestigial nipples. The first is easiest to see, looks like a small mole, the rest look like freckles.

    --
    John McAfee 'It was like that time I hired that Bangkok prostitute; to do my taxes, while I fucked my accountant'
  12. Lifespan? by cyberjock1980 · · Score: 3, Insightful

    So this makes me wonder if people without their Appendix have a different lifespan than those that keep it. I tried to google for the answer, but I came up short. Anyone know of any studies on this subject?

  13. It's confirmation, and I approve by Bigjeff5 · · Score: 5, Insightful

    If you thought you knew this before a study like this came out, then you're as bad as all the other gullible sheep out there, because there was not a large body of good evidence to point to to support that opinion.

    The study in the Qartz article is a review study, looking at hundreds of other studies. It's an extremely important kind of study for solidifying our understanding of how things work, and frankly in my opinion they often don't get enough attention because people think they know these things already. You did not know these things already. You had a couple of articles that you'd seen before that suggested maybe the appendix isn't as useless as doctors used to think, but you didn't have a body of evidence that you could point to to prove that fact. Now you do. That's the importance of the study.

    Of course, in typical fashion the SlashDot summary woefully misrepresents it as a study saying "Hey guys! I found this brand new thing that other people have already found! Check it out!", which of course that isn't what the study was doing at all.

    --
    Security is mostly a superstition... Avoiding danger is no safer in the long run than outright exposure. - Helen Keller
  14. Re:NOT NEWS SLASHDOT! by Bigjeff5 · · Score: 2

    No, scientists had reasonable evidence to suggest that might be a function of the appendix.

    Until there is a large scale review study of all the studies on the subject, just like the study in the article, no reasonable scientist would say the subject was closed.

    The SlashDot summary was terrible, though, so there is that.

    --
    Security is mostly a superstition... Avoiding danger is no safer in the long run than outright exposure. - Helen Keller
  15. Consider the source by tomhath · · Score: 3, Informative

    Midwestern University Arizona College of Osteopathic Medicine

  16. Re:Mystery solved by sexconker · · Score: 2

    Not quite. Being beneficial is not what keeps things around. More often, being detrimental is what gets them removed.

    In times of extreme competition, beneficial traits can statistically outweigh the lack of that trait and become commonplace. (The lack of that trait is detrimental when competition is extremely high.)

    But evolution typically results in beneficial traits leading to specialization (literally, a new species), not the destruction of the old species. It's "why we still got monkeys".

    Beneficial traits have to be beneficial enough to be selected for from that start all the way up to successful reproduction for evolution to "choose" the beneficial trait.
    This has to be done to the widespread exclusion of the lack of the trait to make the trait universal across the species / exterminate the old species.

    Alternatively, detrimental traits only have to be selected against once before reproduction (killing the organism), or during all reproduction attempts, for evolution to "choose" to remove it. Even without a widespread beneficial trait in the species putting pressure against the negative trait, other pressures (climate, predation, etc.) and will ensure it gets removed over time.

  17. Re: Purpose? by Anonymous Coward · · Score: 5, Funny

    The purpose is store sliced carrot. Haven't you noticed that when you vomit there is always carrot in there, even if it has been months since you ate any?

  18. Are you crazy? by Xenna · · Score: 2

    "Midwestern University Arizona College of Osteopathic Medicine"

    Osteopathy is quack medicine!
    How dare you pollute Slashdot in this manner?

    There used to be standards here, or was that before Trump?

  19. Re:You Think You Can Do Without Body Hair? by Boronx · · Score: 2

    Hint: it's you.