Slashdot Mirror
Nicotine Shown To Reduce Symptoms of Schizophrenia (newatlas.com)
New submitter future guy quotes a report from New Atlas: A meta-analysis of worldwide studies conducted in 2005 definitively showed what many doctors had been anecdotally noting for decades. Schizophrenia patients were much more likely to become heavy smokers than than those in the general population. In fact some studies found over 80 percent of those diagnosed with schizophrenia were smokers. There were many social and psychological hypotheses proposed to explain this strange anomaly, but none were ever sufficient. A new study published in Nature Medicine has not only revealed how smoking can normalize the impairments in brain activity associated with schizophrenia, but unlocks an entirely new field of drug research to combat the disease. The study expanded on the recent discovery of a genetic mutation, labelled CHRNA5, that was identified as being associated with the cognitive impairments seen in schizophrenic patients. The scientists took mice with the CHRNA5 gene variant and discovered they displayed similar characteristics to those suffering from schizophrenia, such as an inability to suppress a startle response and an aversion to social interaction. Using brain imaging technologies the research team discovered the mice with the CHRNA5 gene variant displayed symptoms of hypofrontality, a state of decreased blood flow in the prefrontal cortex of the brain. Hypofrontality is commonly thought to be a prominent cause of many symptoms of schizophrenia, as well as being associated with other psychiatric conditions including Bipolar Disorder and ADHD. As well as identifying the role this gene variant plays in causing hypofrontality, the study examined how nicotine acted to restore normal activity to the prefrontal cortex. The researchers found that within one week of daily nicotine dosing the impaired brain activity in mice with schizophrenic characteristics had normalized.
Petco will start selling Marlboros next to the cat food.
Interesting, I suspect that increased Norepinephrine in the prefrontal cortex mediated by the activation of Nicotinic receptors increases prefrontal cortical control over the limbic system. I wonder if Atomoxetine would do the same thing.
Smoke weed
The voices from my microwave have been telling me this for years.
You are welcome on my lawn.
I know it's not the first post but the voices insisted I post anyway. ;)
Anons need not reply. Questions end with a question mark.
it sounds like this should be a commercial. Do you tend to avoid social situations..yes.. do you hear voices..no. does the tv talk directly to you..no. do you think everyone around you is talking about you..of course
light up a cowboy killer. you might have a low blood flow to your prefrontal cortex, and some gene variant that these little tobacco puffers can cure!
studies also show higher intellect leads to less socializing. No desire to talk to dummies is a mental health problem that must be cured. More deliberate dumbing down of the people
I've never been a smoker myself, but my imaginary friend from childhood vanished around the time I started hanging out with smokers. She came back too, shortly after I stopped breathing secondhand smoke. If I ever start smoking firsthand, it might kill her. We've been imaginary friends so long now I just couldn't do that to her.
Hmmm.. That explains why my psycho ex-girlfriend would calm the fuck down when she'd have a cigarette...
Do not look into laser with remaining eye.
Weirdly enough the lung cancer rate of schizophrenics is significantly lower than the population as a whole despite a higher than normal rate of smoking. http://www.schizophrenia.com/s...
Interestingly they also have lower rates of rheumatoid arthritis. Presumably there's a link between the immune system and schizophrenia.
I have a cousin with schizophrenia. He was institutionalized for a few years. I visited him regularly and ended up volunteering to help out at the psych ward. Over time, I met more than a hundred patients. I would say 80-90% of them smoked or used nicotine patches (which were free while cigarettes were not). Compare that to about 11% smokers for the state (California) or 15% for the whole country. This was all back before vaping, which should be a big help for these people, since they can get their nicotine fix without all the crap in tobacco smoke.
In the Western World there is a moral imperative to denounce cigarets, alcohol, drugs and anything that smacks of fun. It is our proud Christian heritage. Right or wrong, we are emotionally dedicated to this cause and will not be deterred by inconvenient facts. Proper taxing and licensing of these corrupt activities can make them technically legal, but never morally acceptable.
The 'inconvenient facts' are that there is an element in each of these activities that benefits society and individuals. In the case of tobacco, one immense benefit is nicotine.
Nicotine is closely related to choline which millions take for mental benefits. It helps students learn and remember. It helps stressed workers and others to feel calm. And nicotine does the same.
Subversive scientists are learning about benefits in alcoholic beverages and illicit drugs despite pressure from legislators and moral dictators and timid journalists who are afraid to publish the findings. Medicine, the law and the church (superstition) are keeping us in the dark ages.
...omphaloskepsis often...
No wonder I'm the only sane person in my family. Everyone else smokes.
A friend of mine worked with schitzos. The medical and government policy was to pile on the tobacco as they all knew it was mostly good for their condition. Even the schitzos knew this as they would do whatever the hell they could for more.
Is this the sort of science that wasn't done as it was so obvious that everyone assumed that it had already been done.
Umm, I'll take schizophrenia instead. So will myself. And me.
*Yes Yes I know you can inject nicotine instead of smoking cigarettes and getting lung cancer. There are after all other types of cancer one could want.
That's not what the voices in my head tell me...
Did not RTFA. I'll just stick with the headline and assume I'm all good from here. Cough cough
to quit smoking.
Bleh, kissing a smoker. Been there, done that, no desire for a repeat.
So, smoking tobacco may cure religion.
I always knew, that people standing in Minus temperatures before buildings in a storm to smoke, were mentally ill.
I vape all of the time and have never had that problem. In fact, vaping helped me to quit smoking and my lung capacity is much better now and improving all of the time.
It sounds like you weren't doing something right, maybe your vape was spitting because you were using dirty atomizers or you weren't cleaning your gear regularly or you were vaping at too low of a wattage. If you are doing it right, it should feel almost like you're pulling air.
And no, vapour is not harmful, otherwise people who live by the sea, who live in foggy or humid areas or areas would have problems. Not to mention people who cook or go to saunas or take hot showers regularly or use facial steamers or use inhalers.
Interesting, I suspect that increased Norepinephrine in the prefrontal cortex mediated by the activation of Nicotinic receptors increases prefrontal cortical control over the limbic system. I wonder if Atomoxetine would do the same thing.
Also see this earlier Slashdot article: https://science.slashdot.org/s...
On that article I responded to:
The title says peppers but it says nicotine is actually the chemical at work. There are actually a few positive effects nicotine possesses, the negative effects of smoking are mediated by the oxidation products of cigarettes.
Which makes me wonder if electronic cigarette products may not only be not bad for you, but even potentially beneficial as they give you a low dose of nicotine through vaporization without the oxidation caused by burning.
https://slashdot.org/comments....
Big apple, new Yorik, undig it, something's unrotting in Edenmark.
Indeed. Suicide, accidents and overdoses have been shown to be very effective at reducing lung cancer rates!
What ? In the same way that a 45 Luger can eliminate a migraine ?
Unicode killed the ASCII-art *
There's more in most vaping liquids than just nicotine and water. I wouldn't call it harmless. But if the choice is between smoking and vaping, the latter is a lot cleaner.
All these links to stories about declassified photos, yet all *I* want to see is one ONE measly photo of the mice, stepping out of this lab, taking a smoke break, just hanging out with these guys in their lab coats. Maybe showing off their "tracks" from other labs, or something.
WARNING: Smartphones have side effects--most of them undocumented.
Well, but there is this...
Technically, this is a hardware problem and may be resolved at some point, but as it is presently integral to the process, I'm pretty comfortable with "vaop(u)r is extremely harmful"
I've fallen off your lawn, and I can't get up.
That's what I like about /.
You make a stupid joke, and from the discussion that follows learn some obscure facts on a completely unrelated topic.
What do cat lovers have to do with anything? Isn't it a documented and indisputable fact that crazy old ladies eat cat food after they have run out of human food in the house? Kind of like: "I'm eating cat food? Must be running out of food... gotta go to the store again!"
In other news, life is a series of tradeoffs.
Indeed. I could have tried to quit, with a very high risk of failure, and put my daughter at risk - or I could take the much more guaranteed but not 100% effective option. I opted for the latter.
Unicode killed the ASCII-art *
Also, people showing those effects while high should forget about ANY substance that plays with serotonin levels.
I'm not going to go into details, but from personal experience I don't think that's a good rule... I'll just say effects of different drugs are, well, quite different from each other, even if they both alter serotonin levels.
Someone had to do it.
Smoking calms people because they are effectively engaging in deep breathing exercises as they smoke. Nicotine is a stimulant and by itself should not calm people.
I just want you to look at yourself and what you just said - you could have tried to quit, and put your daughter at risk... only a severe addict could ever rationalize a statement like that. Keep trying...
News flash: Nicotine is physically addictive, and the act of smoking is psychologically addictive.
Film at eleven.
My mother's psychiatrist gave my mother a nod for smoking. I wish her psychiatrist was there to also hold her hand while she needed 6 liters of oxygen a minute. She's died at 66.
https://www.youtube.com/c/BrendaEM
I tried vaping, it filled my lungs with clear goop and was hard to breathe when I woke up. That shit is very bad for you. I feel it's almost worse than cigarettes. I'm pretty sure you're not supposed to fill your lungs with liquid vapors. At least not that much at a time.
Well, considering that one of the standard treatments for those with COPD involves using a Nebulizer (generally with something like Albuterol infused in the vapor), I would suggest that it is WHAT is being vaporized (the "flavor" chemicals and perhaps the frickin' GLYCOL) that is the issue, rather than "wet lungs" from the vapor itself.
Here's the connection:
1) People generally start smoking weed in their teenage years.
2) Schizophrenia generally becomes symptomatic in the teenage years
3) An diagnosed schizophrenic can have psychosis symptoms from smoking weed
Therefore, to uninformed fucks, weed causes schizophrenia. So far studies imply correlation with zero causation. The rate of schizophrenia does not increase with smoking weed, but some people first notice symptoms concurrently with smoking weed.
This wouldn't even be a discussion if the US government wasn't completely psychotic in its scheduling laws.
When the only tool you have is a claw hammer every problem starts to look like the back of someone's skull.
A) "Same time next month?"
45 Luger
Mom, is that you?? I've told you not to try telling jokes...
Ever kissed a meateater... down there? I will state, for the record... that vegetarian chicks definitely taste better.
Youre probably very correct, seeing as the ingredients in vape jizz is all oil bases. I figured after a month it wasnt worth it having to "build" coils and shit was a waste of time. plus it was making me feel like crap, so i just stopped it. I highly recommend not trying any of the vape "mods" or anything thats for "blowin' clouds" i figure it will eventually be outlawed.
How disrespectful. What a way to talk to your mother. Go to your womb !
Unicode killed the ASCII-art *
Ever kissed a meateater... down there? I will state, for the record... that vegetarian chicks definitely taste better
To borrow from another joke, I respond: Wrong Hole!
https://app.box.com/WitthoftResume Code: https://github.com/cellocgw
... that's not exactly an obscure fact if you know anything about guns. Nothing wrong with being ignorant of a field - god knows I'm a babe in the woods about a lot of things - but seriously, those are two of the most popular pistol rounds ever, for two of the most famous pistols ever.
Youre probably very correct, seeing as the ingredients in vape jizz is all oil bases. I figured after a month it wasnt worth it having to "build" coils and shit was a waste of time. plus it was making me feel like crap, so i just stopped it. I highly recommend not trying any of the vape "mods" or anything thats for "blowin' clouds" i figure it will eventually be outlawed.
I would imagine that the vapes that are designed around Tobacco might be targeted at temps different for those that are designed for vaping Marijuana. At least that would be what I would hope.
But once you start listening to the modders and coil-winders, all bets are off. Most of those people don't even know the difference between vaping and combusting. They just want a big "cloud", as you said.
What ? In the same way that a 45 Luger can eliminate a migraine ?
OMG the assault rifle ban is going to cause a migraine epidemic!
Apocalypse Cancelled, Sorry, No Ticket Refunds
Smoking calms people because they are effectively engaging in deep breathing exercises as they smoke. Nicotine is a stimulant and by itself should not calm people.
Yeah that's why they give kids amphetamines so they can sit still isn't it.
Apocalypse Cancelled, Sorry, No Ticket Refunds
A pistol is now an assault rifle ?
Unicode killed the ASCII-art *
Google "vape juice ingredients" and you will see that I fact I'm right and you made yourself look like a moron. I looked into making my own and I know people that make their own.
Well that goes back to 90% of youtubers are morons and have nfi what their talking about most of the time. I watched a few videos a while back and the guy was trying to explain ohms law. I'm an electrician by trade for 16 years.. I had to turn it off it was so misinforming
Well that goes back to 90% of youtubers are morons and have nfi what their talking about most of the time. I watched a few videos a while back and the guy was trying to explain ohms law. I'm an electrician by trade for 16 years.. I had to turn it off it was so misinforming
LOL! I feel ya!
I am an electrical engineer by trade (or I was before I pissed-off my boss for outing him as a poser...). One of the warning signs I have always used to determine when someone is just b.s.-ing is when they start sticking-together terms-of-art that don't go together. I am SURE that laughable YT video had a metric buttload of that "fun-ness"...
Lugers are 9mm not 0.45 inch; shoot someone in the leg with a 9mm an ambulance takes them to the hospital, with a 45APC, the leg probably comes mostly off and they bleed out. A lot of anti-gun people would consider the Thompson an assault rifle.
Apocalypse Cancelled, Sorry, No Ticket Refunds
A last-ditch effort to attract the only customer deemed worthy of the product?
Requiem for the American Dream
What worked for me was picturing some giant overbearing asshole behind a big desk (potentially wearing some kind of cowboy hat) leaning over the desk to bark an order to a minion re. enforcing his will over the world's population solely for his own financial gain. What a fucker. Don't buy him another five-pool yacht.
Requiem for the American Dream
Smoke weed mixed with tobacco!?
Requiem for the American Dream
* 'weed causes psychosis'
* 'tobacco fixes it'
* weed can't be taxed as easily as tobacco
* therefore weed is bad
Requiem for the American Dream
Which, presumably is the next logical step?
Requiem for the American Dream
Actually, wrong, 45 Cal Lugers DO exist. They are very rare and only a few were ever made, but they are a thing. At least one was plated in gold and last sold at auction for over a million dollars.
Unicode killed the ASCII-art *
Many (all?) antipsychotic drugs have some heavy side effects. Patients pretty much have to decide between illness, obesity, parkinson symptoms or any combination of those 3. No wonder they might get heart diseases.
Yes, One of my favorites who is intelligent and knows what hes talking about whether its from a previous education or just researching before he makes his videos, is AvE That guy is awesome. Most others that talk about anything technical just fuck shit up. Also got to remember part of job security is covering your bosses fuck-ups and inexperience. Im from Las Vegas, NV The land of the Self Proclaimed Journeyman. Makes my job hard, My main job when im not running a job of my own is to travel from job to job fixing peoples fuckups.. Makes for a nice job for me as i get to fuckoff and use my brain to figure out what the guy was attempting to do. Also stressful, so i smoke weed(and its legal here now!)