First Human Embryos Edited In US (technologyreview.com)

← Back to Stories (view on slashdot.org)

First Human Embryos Edited In US (technologyreview.com)

Posted by BeauHD on Thursday July 27, 2017 @10:00AM from the there's-a-first-for-everything dept.

randomErr shares a report from MIT Technology Review: The first known attempt at creating genetically modified human embryos in the United States has been carried out by a team of researchers in Portland, Oregon, MIT Technology Review has learned. The effort, led by Shoukhrat Mitalipov of Oregon Health and Science University, involved changing the DNA of a large number of one-cell embryos with the gene-editing technique CRISPR. Until now, American scientists have watched as scientists elsewhere were first to explore the controversial practice. To date, three previous reports of editing human embryos were all published by scientists in China. Now Mitalipov is believed to have broken new ground both in the number of embryos experimented upon and by demonstrating that it is possible to safely and efficiently correct defective genes that cause inherited diseases. In altering the DNA code of human embryos, the objective of scientists is to show that they can eradicate or correct genes that cause inherited disease, like the blood condition beta-thalassemia. The process is termed "germline engineering" because any genetically modified child would then pass the changes on to subsequent generations via their own germ cells -- the egg and sperm. Reached by Skype, Mitalipov declined to comment on the results, which he said are pending publication. But other scientists confirmed the editing of embryos using CRISPR.

140 comments

Min score:

Reason:

Sort:

Gattaca predicted the outcome in 1997 by omfglearntoplay · 2017-07-27 10:05 · Score: 2, Insightful

http://www.imdb.com/title/tt01...
This is heading us into a scary and evil world. Not to mention all the screw-ups that will happen. Edit gene blah to fix pimples... whoops that gives you an automatic heart attack at age 30.
A few years back I remember seeing all the Chinese scientists talking about editing human genes so that they would not crave meat. It'd be cheaper to feed them that way. GREAT IDEA, WHAT COULD GO WRONG?!!!!
1. Re:Gattaca predicted the outcome in 1997 by avandesande · 2017-07-27 10:12 · Score: 1
  
  You could say the same thing about the invention of the automobile but somehow we survive (at least most of us)
  
  --
  love is just extroverted narcissism
2. Re:Gattaca predicted the outcome in 1997 by green1 · 2017-07-27 10:17 · Score: 2
  
  Gattaca was more about reading the genes and discriminating based on it. (there are plenty of other films that talk about what could go wrong by making edits that result in unforeseen complications) Refusing to hire someone because their genes say their life expectancy isn't long enough to be worth training them, or who is expected to have more sick days than you want, or who has a condition that will be expensive for the corporate health plan to treat.
  Gattaca predicted that we'd be able to read more in to the results of a genetic test than we currently can, but it may still happen. It also predicted that genetic testing would be cheap and easy for corporations to do.
  Interestingly enough, it also predicted that governments would outlaw the practice of doing so, but that corporations would ignore the law and do so anyway because it would be easy to do under the guise of drug testing, or any other excuse that gave up a few skin cells, a hair follicle, or any blood/urine/etc.
3. Re:Gattaca predicted the outcome in 1997 by jedidiah · 2017-07-27 10:25 · Score: 2
  
  Not even remotely close. This is more like the development of the atomic bomb. Nice to see that this group isn't any smarter than anyone else and doesn't have to sense to have some apprehension about this.
  
  --
  A Pirate and a Puritan look the same on a balance sheet.
4. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 10:25 · Score: 0
  
  Have you actually seen the movie or just bringing it up because someone else has talked about it?
  Gattaca was about discriminating based on your genes. I don't recall anything about editing genes. But what do I know, I've only seen the movie 5 or 6 times and the last time was at least 10 years ago.
5. Re:Gattaca predicted the outcome in 1997 by jedidiah · 2017-07-27 10:29 · Score: 1
  
  The whole reason the protagonist was shat on was because he was a naturally conceived baby. It was not clear if babies were engineered or merely selected but the same level of genetic understanding was implied.
  I think the real problem with this is that we're not nearly as smart as we think we are and this is tinkering with people. With people that are dying, this kind of thing makes more sense from the risk/reward perspective.
  
  --
  A Pirate and a Puritan look the same on a balance sheet.
6. Re:Gattaca predicted the outcome in 1997 by alvinrod · 2017-07-27 10:33 · Score: 2
  
  I don't think it's necessarily evil any more than any other technology is. The same technology that can do all of the harm that you imagine can also eliminate diseases and other manners of affliction. Humanity has faced this dilemma throughout history, and some have chosen poorly, but those who choose wisely tend to end up ahead of the curve and humanity advances.
7. Re:Gattaca predicted the outcome in 1997 by Hognoxious · 2017-07-27 10:37 · Score: 2, Funny
  
  I've only seen the movie 5 or 6 times and the last time was at least 10 years ago.
  It could have changed a fair bit since then.
  
  --
  Confucius say, "Find worm in apple - bad. Find half a worm - worse."
8. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 10:40 · Score: 0
  
  You could say the same thing about the invention of the automobile
  Editing human genes is absolutely nothing like the invention or adoption of the automobile. Not objectively, not in analogy, not practically, not ethically, not legally, not economically, and not in it potential social, cultural, civic or national repercussions. It's not even the same scientific field, or material phase!
  You may as well say the invention of the automobile was the same thing as the writing of the Tales of Baron Munchausen.
9. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 10:41 · Score: 0
  
  what's to prevent anybody from having a heart attack at 30 without genetic modification?
10. Re: Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 10:43 · Score: 0
  
  Back to your buggy whip factory, Luddite.
11. Re:Gattaca predicted the outcome in 1997 by NEDHead · 2017-07-27 10:44 · Score: 1
  
  Perhaps it has been re-edited...
12. Re: Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 11:02 · Score: 0
  
  Back to your rickshaw pulling job, slave. Your master has a new whip to break in.
13. Re:Gattaca predicted the outcome in 1997 by interkin3tic · 2017-07-27 11:05 · Score: 2, Insightful
  
  Edit gene blah to fix pimples... whoops that gives you an automatic heart attack at age 30.
  TLDR: it will be illegal to perform the type of edits you're worried about.
  
  Doctors doing this to people would be legally required to follow ethics guidelines. Researchers in lab don't have to since they're not doing research on people*.
  
  Those ethical guidelines were already being debated heavily when it was even more hypothetical than it is now. Steven Pinker is probably the most gung ho guy for "do germline editing" and even he seems to suggest no edits for purely cosmetic reasons. The guidelines will be codified into policy for clinics wanting to do this in people. The safe money is that they specifically ban any edits that aren't correcting life-threatening conditions like cystic fibrosis. I would bet that there will be a short list of conditions and mutations that would be approved for correction. These would be well documented mutations that are purely negative, and the fixes approved will be restoring it to "normal" sequences.
  
  I would bet my house that human augmentation, making embryos that are better faster stronger (Work is never over) than normal would not be allowed in the US in the foreseeable future.
  
  "What could go wrong" is that the editing could fail in some cases, and you'd abort the pregnancy, much like people do now when they discover via amniocentesis that their embryos have life-ending mutations.
  
  Also superhuman zombie babies could destroy the earth like in "I am Legend" only with smaller vampire creatures. In movies which will inevitably be made.
  
  (* Any pro-lifers out there wanting to debate this off-topic point are free to instead yell it into the wind and get it out of their system faster)
14. Re: Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 11:06 · Score: 0
  
  He's probably been gene-edited to have at least 1% animal DNA, and couldn't actually scientifically differentiate himself from one anyway.
  No need to bother thinking the slave has any annoying human-specific "rights".
15. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 11:07 · Score: 0
  
  Current genetics?
16. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 11:09 · Score: 0
  
  this is tinkering with people.
  That is a good thing.
17. Re:Gattaca predicted the outcome in 1997 by KiloByte · 2017-07-27 11:11 · Score: 3, Insightful
  
  even he seems to suggest no edits for purely cosmetic reasons. The safe money is that they specifically ban any edits that aren't correcting life-threatening conditions
  And even safer money says a huge industry of cosmetic edits will pop up before life-threatening conditions even start regulatory approval trials. You'll just need to fly out of the country to do so.
  
  --
  The creatures outside looked from Alt-Right to Antifa; but already it was impossible to say which was which.
18. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 11:16 · Score: 0
  
  Doctors doing this to people would be legally required to follow ethics guidelines.
  And we have reassuring precedent for this being maintained.
  Like, 1938 Germany.
19. Re:Gattaca predicted the outcome in 1997 by Kjella · 2017-07-27 11:20 · Score: 2
  
  Gattaca predicted that we'd be able to read more in to the results of a genetic test than we currently can, but it may still happen. It also predicted that genetic testing would be cheap and easy for corporations to do.
  Well I don't know about corporations, but I think we're nearing the point where it ought to be a no-brainer for medicine. Your DNA doesn't change, that means if we sequence a newborn today it's good for ~80 years of treatments and 80 years of accumulating knowledge and the cost is now around $1000. So like $12.50 a year to know your current and future risk factors, even if it's almost useless the amortized cost is trivial. Of course that's assuming we stick this result in a database somewhere... a lot of people aren't not going to be happy about that. There's got to be a lot of info in there though on what nature has given us...
  
  --
  Live today, because you never know what tomorrow brings
20. Re:Gattaca predicted the outcome in 1997 by ShanghaiBill · 2017-07-27 11:31 · Score: 0
  
  Gattaca was more about reading the genes and discriminating based on it.
  Gattaca was a stupid movie. They were screening people to ensure they were qualified to be astronauts. This is something WE ALREADY DO. No one with a defective heart should be sent into space at taxpayer expense. If genetic testing can streamline and improve the screening then of course we should be doing it.
21. Re:Gattaca predicted the outcome in 1997 by ShanghaiBill · 2017-07-27 11:35 · Score: 2
  
  The other no brainer is saving stem cells from the umbilical cords of newborns. These cells can be stored in liquid N2 at negligible cost, and used to treat all sorts of disorders later in the kid's life, as well as used for anti-ageing and life extension. Yet it is almost never done.
22. Re:Gattaca predicted the outcome in 1997 by ShanghaiBill · 2017-07-27 11:41 · Score: 1
  
  The whole reason the protagonist was shat on was because he was a naturally conceived baby.
  He had a defective heart, as well as other health problems that made him completely unqualified to be an astronaut. Since the genetic testing would have found these problems, it actually made a lot of sense to use it.
23. Re:Gattaca predicted the outcome in 1997 by ShanghaiBill · 2017-07-27 11:51 · Score: 1
  
  TLDR: it will be illegal to perform the type of edits you're worried about.
  
  It is unlikely to be illegal everywhere. Medical tourism is already a big business.
  What is wrong with gene editing to fix pimples, if the treatment is proven safe and effective? Severe acne can be emotionally devastating, and have physical consequences such as secondary infections. Why should the government be making that decision instead of leaving it to informed individuals and their doctors?
24. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 12:05 · Score: 0
  
  Doctors doing this to people would be legally required to follow ethics guidelines.
  And we have reassuring precedent for this being maintained.
  Like, 1938 Germany.
  And OJ.
25. Re: Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 12:14 · Score: 0
  
  What do you consider negligible costs? When my first son was born, in 2012, this option was presented but had a price tag of several thousand dollars. We had already hit our insurance out of pocket max on my wife so the pregnancy ended up costing us $6,000. To add another few thousand on top of that was tough to swallow because it's so abstract.
  My second son still born in 2015 would have cost us a few thousand dollars to save the stem cells. We had much better insurance then (my wife is a nurse) so that pregnancy only cost us about $3,000. However after eating 2 years of the other children's childcare costs (about $15,000/yr) on top of the general expense of a child it's tough again to justify an abstract extra few thousand dollars.
  I make well above the medium family income by myself, but there is nothing reasonable about the cost of harvesting and saving those stem cells.
26. Re:Gattaca predicted the outcome in 1997 by grep+-v+'.*'+* · 2017-07-27 12:23 · Score: 1
  
  but those who choose wisely tend to end up ahead of the curve and humanity advances
  So you're saying the wise normal humans will be running in front of the horde of 3 headed zombies, all chanting "brains, Brains, BRAINS"?
  
  It's just another tool, neither good or bad. It's how it's used by it's wielder is what actually counts. Hopefully they experiment on themselves first.
  
  --
  If the universe is someone's simulation -- does that mean the stars are just stuck pixels?
27. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 12:51 · Score: 0
  
  Tech isn't evil. People are evil. The existence of evil people is not an argument against research and experimentation.
  You fear the unfamiliar, so you resist it. But in your fear you fail to see the amazing potential for good that tech like this can do.
  I have been cursed with terrible acne for my entire life. It has had severe impacts on my mental health and my social life. If a simple genetic procedure means nobody will have to endure this life-crushing indignity again, then I am ALL FOR IT!
  Things might go wrong. That's part of the journey. But by taking that risk, the pioneers make the world a much better place for everyone else.
  It is worth it.
28. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 12:54 · Score: 1
  
  The atomic bomb killed a lot of people.
  And ended a terrible worldwide war that would have otherwise gone on to kill WAY MORE people.
  It has also, so far, prevented a third such war.
  Yes, tech like this must be taken seriously. But it must not be flatly rejected out of fear.
  We need it.
29. Re:Gattaca predicted the outcome in 1997 by avandesande · 2017-07-27 12:56 · Score: 0
  
  Really, gene editing has zero useful social functions like curing congenital heart defects, or adding aids resistance or any of the thousand of benefits? You are a moron.
  
  --
  love is just extroverted narcissism
30. Re: Gattaca predicted the outcome in 1997 by ShanghaiBill · 2017-07-27 13:13 · Score: 1
  
  this option was presented but had a price tag of several thousand dollars.
  It is expensive because almost no one does it. If it was routine, it would be cheap. Definitely less than $1000. That cost would be recouped many times over in savings later in life. Got liver cancer? Just grow a new one from your own stem cells.
31. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 13:14 · Score: 0
  
  If we have the means of curing terrible genetic diseases, it would be unethical not to do so.
  Compelling others to suffer because you are afraid of the learning process is terribly selfish and short-sighted.
32. Re: Gattaca predicted the outcome in 1997 by ChrisMaple · 2017-07-27 14:41 · Score: 1
  
  Just what do you think human beings are? Plants? If you're a land-dwelling macroscopic living thing, you're either plant or animal. No third choice.
  
  --
  Contribute to civilization: ari.aynrand.org/donate
33. Re:Gattaca predicted the outcome in 1997 by BlueStrat · 2017-07-27 14:59 · Score: 4, Insightful
  
  Really, gene editing has zero useful social functions like curing congenital heart defects, or adding aids resistance or any of the thousand of benefits? You are a moron.
  You have to admit that this new ability to edit human genes does have the potential to be used in some pretty damned creepy and dangerous ways. Couple that with human nature and you're almost assured it will be, at some point. Do you believe someone like Kim Jong Un and N. Korea would hesitate to create "super-soldiers" and more with this?
  An abundance of caution going forward is not uncalled-for considering the possible uses and results along with their depth, scope, and implications for humanity's future.
  Strat
  
  --
  Progressivism (aka US 'Liberalism'): Ideas so good they need a police/surveillance-state to enforce.
34. Re: Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 15:06 · Score: 0
  
  Just what do you think human beings are? Plants? If you're a land-dwelling macroscopic living thing, you're either plant or animal. No third choice.
  Animalia-plantea (sic)? : )
35. Re: Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 15:09 · Score: 0
  
  Just what do you think human beings are? Plants? If you're a land-dwelling macroscopic living thing, you're either plant or animal. No third choice.
  Animalia-plantea (sic)? : )
  Okay, macroscopic...although......
36. Re:Gattaca predicted the outcome in 1997 by Applehu+Akbar · 2017-07-27 15:11 · Score: 1
  
  You have to admit that this new ability to edit human genes does have the potential to be used in some pretty damned creepy and dangerous ways. Couple that with human nature and you're almost assured it will be, at some point.
  But if we refuse to use it for good, we're not putting the GMO toothpaste back in the tube. We would be leaving the field wide open for North Korea and ISIS.
37. Re: Gattaca predicted the outcome in 1997 by Applehu+Akbar · 2017-07-27 15:14 · Score: 2
  
  "I make well above the medium family income by myself, but there is nothing reasonable about the cost of harvesting and saving those stem cells."
  You're confusing cost with price.
38. Re:Gattaca predicted the outcome in 1997 by BlueStrat · 2017-07-27 15:38 · Score: 1
  
  But if we refuse to use it for good,...
  My exact words were; "An abundance of caution going forward is not uncalled-for..."
  Nowhere did I state nor imply that I thought a ban was a solution. In fact I did not offer any solutions, as quite frankly, it's a damned difficult question with many very fundamental principles involved, many in possible opposition to one another. There are no simple solutions here, particularly as the CRISPR-cat is out of the bag and already used on human embryos, and most Western governments as yet have near-zero policy structure and regulatory outlines even being seriously discussed by their lawmakers, regulators, and leaders.
  Strat
  
  --
  Progressivism (aka US 'Liberalism'): Ideas so good they need a police/surveillance-state to enforce.
39. Re:Gattaca predicted the outcome in 1997 by jezwel · 2017-07-27 15:45 · Score: 2
  
  I considered this with the recent birth of my son, however with adult stem cells now identified it didn't seem like they would be needed in the future. Plus the cost was another factor is declining this. All I can do now is cross my fingers and hope that science proceeds apace with adult stem cell processes becoming cost effective for more treatments.
40. Re:Gattaca predicted the outcome in 1997 by interkin3tic · 2017-07-27 16:11 · Score: 1
  
  Sure, but that will happen no matter what scientists and doctors here in the US do, so what's your point?
41. Re:Gattaca predicted the outcome in 1997 by interkin3tic · 2017-07-27 16:14 · Score: 1
  
  The government of Germany engaged in eugenics, therefore our government will approve crispr use for making superhumans?
  
  Ugly truth of Germany was that a good number of Germans were totally in favor of genocide at that time. I don't see that level of support for making designer babies here in the US now. And, if most people are convinced designer babies are a good thing, it's going to happen anyway. What's the alternative? Burning all knowledge of CRISPR? Little late for that.
42. Re:Gattaca predicted the outcome in 1997 by interkin3tic · 2017-07-27 16:17 · Score: 1
  
  OJ was not licensed to do anything you're talking about by a medical board.
  
  Doctors wouldn't be able to advertise superhuman babies services and keep their licenses and access to the facilities they'd need to do this work. It's much more regulated than using a knife and gloves like OJ did, and can't be done in as much secret or quickly.
43. Re:Gattaca predicted the outcome in 1997 by interkin3tic · 2017-07-27 16:24 · Score: 0
  
  It is unlikely to be illegal everywhere. Medical tourism is already a big business.
  Sure, but we were talking specifically within the US here. CRISPR clinics elsewhere may pop up, but that was going to be true no matter what we did in the US, and would have been true even if the current study hadn't been done.
  
  Why should the government be making that decision instead of leaving it to informed individuals and their doctors?
  The ethics discussion panels I was talking about are being done by scientists and doctors, not the government. I believe medical boards which issue and can revoke medical licenses are made up of doctors, the ones making the medical guidelines too. So "the government" in this case WOULD be the informed individuals and doctors.
  
  What is wrong with gene editing to fix pimples, if the treatment is proven safe and effective? Severe acne can be emotionally devastating, and have physical consequences such as secondary infections.
  I linked to two discussions of the ethics. Steven Pinker can easily be contacted online, as can George Church and the other people weighing in on the ethics. They've discussed at length their ethical concerns. You can read them online. You can probably get in contact with them and raise these points at any future ethics meetings, or write opinion articles for science magazine or other journals if you want.
  
  If you're actually asking and not just trying to make a point lazily, I'd say because that's unethical for reasons discussed at length elsewhere, and you should start reading the two links I provided. I'm not going to do your homework for you.
44. Re:Gattaca predicted the outcome in 1997 by hey! · 2017-07-27 16:27 · Score: 1
  
  Well, I think the immediate application will be to be able to have children who won't have to worry about developing Huntington's and other genetic diseases where we can zero in on a single gene, or perhaps several genes.
  But the things that make a human admirable or superior are nigh-imperfect aren't going to translate into genes in any way we will be able to figure out anytime soon.
  One of the big surprises when the human genome was decoded is that it is far, far smaller than anyone had suspected. We expected over 100,000 protein-encoding genes, we found fewer than 20,000. What this means is that the way DNA directs the undifferentiated cells of a blastula to turn into a human isn't anything like reading a blueprint, where there's a 1-to-1 correspondence between a part of the blueprint and the actual end result. It's more like the Mandelbrot set, where an immensely complex and unexpected landscape emerges from very terse instructions.
  So I don't think we'll be able to edit peoples genes to make them successful, or intelligent; not anytime soon at least. We'd probably be able to tweak features like eye color, although that may have unintended consequences. Changing a single behavior like liking to eat meat is questionable; food likings are largely a product of culture and habituation. Brute force methods, say disabling the glutamate receptors on the tongue, are likely to have unintended consequences.
  
  --
  Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
45. Re:Gattaca predicted the outcome in 1997 by rtb61 · 2017-07-27 16:41 · Score: 3, Insightful
  
  Well in this case, the claim "by demonstrating that it is possible to safely and efficiently correct defective genes", is a bit fat lie. The only way that it is possible to demonstrate that is to allow the experiment to reach maturity. You might have managed your change but it is extremely hard to tell how much damage you have down especially to what they used to call junk genes, which in reality are a complex set of interrelated genes that don't turn stuff on or off but adjust how much they are turned off or on. Do not claim value or safety until the experimental subject has achieved maturity, else it is a lie.
  
  --
  Chaos - everything, everywhere, everywhen
46. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 16:53 · Score: 0
  
  The whole reason the protagonist was shat on was because he was a naturally conceived baby.
  He had a defective heart, as well as other health problems that made him completely unqualified to be an astronaut. Since the genetic testing would have found these problems, it actually made a lot of sense to use it.
  He did not have a defective heart, genetic testing gave a high probability of heart problems and other issues. When his parents have a second child they opt for the procedure to have their child not have congenital defects and they could also choose the eye and hair color. Its not discussed how this is done which is good since there could be any number of technologies that could produce the same result which were not fully comprehended at the time. It also gives the movie a bit of a timeless quality since it has a pretty stylized design it can seem to take place in almost any time.
  Now the love interest played by Uma Thurman did have a defective heart that she had to take medication for.
  The issue the movie presents is that genetic testing and manipulation supposedly make a superior person and that you are only as good as your genetic outcomes predict. It was not that the protagonist did not have the ability, drive, or intelligence to become an astronaut but that he was judged on a genetic test that gave some probabilities that he MAY develop certain conditions. He was not even given the chance to prove that he could do it, one look at his genetic results and thats it.
  In the movie this creates 2 classes of citizens those who have been engineered and those who have not for either personal, religious or maybe that they can not afford it. There seemed to be quite a few who were born natural so if everyone could afford the procedure it would seem unlikely most would not take it. The protagonists family are presented as middle class so it would seem that would be the minimum bar to entry for this. Although economics is not much discussed through the movie so this is conjecture.
  Anyway this can be a boon to society but real discussions need to take place on the implications of this technology and who should have access to it (Everybody)
47. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 19:37 · Score: 0
  
  Thanks for lumping me in with everyone else. Been talking for deaf ears since 1997..
  Btw, nuclear energy is da bomb, and everyone who disagree are stupid.
48. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 20:01 · Score: 0
  
  Did you even watch the movie?
  The point of the main plotline was that DNA based discrimination is wrong and was wrong. He lived far beyond what the DNA tests expected and did things that the science said was impossible.
  
  If genetic testing can streamline and improve the screening then of course we should be doing it.
  And genetic testing shows the average person with African ancestry has an IQ of 85 and Europeans have an average IQ of 108. IQ certainly is an important measure in screening astronaut candidates.
  Does a person's ethnicity determine their capability?
  Are you for racism? Are you for discriminating based on science with low predictability?
49. Re:Gattaca predicted the outcome in 1997 by enrique556 · 2017-07-27 20:17 · Score: 1
  
  There is no technology that mankind has so far invented that can do as much for individuals or mankind as a whole as CRISPR.
  Here we have news of a huge breakthrough in human genetic engineering, and someone's deferring to a second rate sci fi fantasy hollywood movie for guidance.
  Makes me wonder why we even bothered separating church from state so long ago.
50. Re: Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 20:20 · Score: 0
  
  you're either plant or animal. No third choice.
  Er...ever heard of fungi?
51. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 20:28 · Score: 0
  
  What's the alternative? Burning all knowledge of CRISPR? Little late for that.
  Alternative is to allow all those implicitly or explicitly defining themselves as just another arbitrary permutation of DNA, to hold them to their self-definition, and treat them accordingly.
  Permanently.
  And the relevant timeframe is "little early", not "little late".
52. Re: Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-27 20:38 · Score: 0
  
  Is this where I offer you a bet for your soul?
  Come on... no risk, right?
  CAPTCHA: pointy
53. Re:Gattaca predicted the outcome in 1997 by parkinglot777 · 2017-07-27 23:55 · Score: 1
  
  Well in this case, the claim "by demonstrating that it is possible to safely and efficiently correct defective genes", is a bit fat lie. The only way that it is possible to demonstrate that is to allow the experiment to reach maturity. You might have managed your change but it is extremely hard to tell how much damage you have down especially to what they used to call junk genes, which in reality are a complex set of interrelated genes that don't turn stuff on or off but adjust how much they are turned off or on. Do not claim value or safety until the experimental subject has achieved maturity, else it is a lie.
  I completely agree. Though, scientists nowadays like advertising so that they can get more grants to do things they want to do. I am not saying it is a bad thing, but many of them are abusing the Internet to make fame before the real result from their researches are in...
54. Re:Gattaca predicted the outcome in 1997 by bluefoxlucid · 2017-07-28 01:35 · Score: 2
  
  Man we should fix that last metabolic pathway in the Vitamin C cycle. Vitamin C is awesome. Mega-dosing Vitamin C won't cure your cold or flu; but high doses (like, 500mg/day) will remove mercury and lead from your body.
  Vitamin C regulates prolactin, helps generate Dopamine and Norepinephrine, donates two electrons to act as a powerful anti-oxidant while itself not radicalizing, helps with cell wall building, helps to counter damage and stress caused by cortisol release, and generally does a whole lot of important stuff to your body. Vitamin C improves sleep, cholesterol levels, attentiveness, and (yes) the functioning of your immune system, relative to a C-deficient human.
  Humans have the framework to produce Vitamin C in the liver, and carry a defective gene for the last coding protein. That's why we need dietary Vitamin C. Most animals produce it internally, which is why your cat isn't on a steady diet of oranges and prune juice.
  
  --
  Support my political activism on Patreon.
55. Re:Gattaca predicted the outcome in 1997 by Neuronwelder · 2017-07-28 01:52 · Score: 1
  
  You said scary and evil. Point taken.. While it does promise corrections in genetic defects.. Who's hands is it going to be in?? The Good? or The Bad? Its a subject with lot to think about..
56. Re:Gattaca predicted the outcome in 1997 by PoopJuggler · 2017-07-28 02:38 · Score: 1
  
  The automobile has destroyed the atmosphere...
57. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-28 02:55 · Score: 0
  
  They will have to ruminate their meals all day long like elepahnts and cows.
58. Re:Gattaca predicted the outcome in 1997 by ShanghaiBill · 2017-07-28 05:30 · Score: 1
  
  So "the government" in this case WOULD be the informed individuals and doctors.
  You seem to be confused about what "individual choice" means. When someone says that decisions about, say, medical procedures, speech, and property should be left up to "individuals", they mean the individual who actually inhabits the body affected, is voicing the opinion, or owns the relevant property. They do NOT mean just ANY individuals, such as the police, or an "ethics panel", or even the voting public, even though these are indeed made up of "individuals".
59. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-28 06:21 · Score: 0
  
  If we have the means of curing terrible genetic diseases, it would be unethical not to do so.
  Compelling others to suffer because you are afraid of the learning process is terribly selfish and short-sighted.
  That's assuming the means themselves are ethical and the side effects of the cure aren't worse than the disease. Both of which are absolutely essential questions that should guide everything in biotechnological research.
60. Re:Gattaca predicted the outcome in 1997 by RespekMyAthorati · 2017-07-28 16:12 · Score: 1
  
  Who's hands is it going to be in?? The Good? or The Bad?
  
  Nope, the Ugly.
61. Re: Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-28 18:25 · Score: 0
  
  The atomic bomb killed a lot of people.
  And ended a terrible worldwide war that would have otherwise gone on to kill WAY MORE people.
  As with the flu, if you take a pill and you get well, you don't know the outcome without the pill.
  Correlation is not causation.
  I was taught to think the same way, and did, until I read about the bat bomb, amongst other things...
  Read about it, you can find it on Wikipedia and other places.
  It has also, so far, prevented a third such war.
  It has done no such thing. Politicians have. Of all people...
  Yes, tech like this must be taken seriously. But it must not be flatly rejected out of fear.
  We need it.
  I'm not saying we don't, but I find no argument in your comment to agree with your final statement.
  My view: it remains to be seen.
62. Re:Gattaca predicted the outcome in 1997 by Anonymous Coward · 2017-07-28 20:00 · Score: 0
  
  You must get a lot out of literature if you thought Gattaca was about screening astronauts. FYI, it's about the ability of the human spirit to overcome both our personal limitations and the totally prescribed lives in a dystopian future where a DNA-based caste system determines the outcome of everybody's life. And like all good sci-fi, it's a really a commentary/warning about the world of today rather than the dystopian future—we already have an economic caste system that largely determines outcomes sans the DNA-editing.
  I'm sorry you didn't enjoy a classic sci-fi film because you misunderstood it to somehow be against genetic testing. Maybe stick to less cerebral fare like the one where the oil drillers blow up an asteroid with nukes.
Re:Happy Thursday from The Golden Girls! by Ann+O'Nymous-Coward · 2017-07-27 10:08 · Score: 1

*chortle* Uh, that's 'confidante'.
Gotta love those Mondegreens.
Point Mutations by Anonymous Coward · 2017-07-27 10:15 · Score: 0

Start with fixing the point mutations before mass producing Mirandas. -- Father Henry, forcibly retired
better than /. editors by turkeydance · 2017-07-27 10:15 · Score: 1

we hope
American embryos edited by a Russian, no surprise by Anonymous Coward · 2017-07-27 10:16 · Score: 0

First they tampered with our elections, now they're tampering with our babies! What's next? Our vodka?!
You know science has gone too far.... by Zephyn · 2017-07-27 10:23 · Score: 5, Funny

....when even the cannibals have to start worrying about GMOs.
1. Re:You know science has gone too far.... by Anonymous Coward · 2017-07-27 12:07 · Score: 0
  
  Yeah, but the cannibals no longer crave meat, remember. Science fixed that.
  Now that cannibal mushroom over there. Watch out for that thing.
Re:American embryos edited by a Russian, no surpri by dejitaru · 2017-07-27 10:25 · Score: 1

i'd hope russians tamper with our vodka, I love russian vodka
Its dangerous, but so are all important advaces by joe_frisch · 2017-07-27 10:26 · Score: 1

Technological and scientific advances have the potential to drastically change the world. That's why they are valuable. That's why they are dangerous.
I don't want to stop or even slow genetic research BUT, I would like to see real work put into developing rules to try to prevent some of the possible nightmare futures it could create.
1. Re:Its dangerous, but so are all important advaces by ShanghaiBill · 2017-07-27 12:04 · Score: 1
  
  I would like to see real work put into developing rules
  How are you going to enforce these rules? You can already buy CRISPR kits on eBay.
2. Re:Its dangerous, but so are all important advaces by Anonymous Coward · 2017-07-27 12:46 · Score: 1
  
  I've never thought of keeping embryos in the crisper.
3. Re:Its dangerous, but so are all important advaces by joe_frisch · 2017-07-27 14:42 · Score: 1
  
  You won't always be able to enforce them but if, for example, home DNA hacking is seen as a major threat you could probably restrict and track technologies the way it is done for nuclear technology. (if there were no restrictions, a homemade nuclear bomb is not impossible).
  You can also arrest and imprison people when they are caught doing illegal mods.
  It may not be necessary. The technology to effectively modify humans may require a large infrastracture. Or maybe not?
  I agree with your general point though that we need to think about enforcement as well.
  (Of course large bio-med companies will argue that only large bio-med companies should have access to this technology....)
They edited the first human embryos? by Anonymous Coward · 2017-07-27 10:26 · Score: 1

They edited the first human embryos? Can you believe that? The first human embryos ever and they went and edited them rather than keep them in their original state.
Come to think about it, I'm surprised that they managed to find the first human embryos. Also that they still exist, and are still embryos.
Confirmed... I read the article by Anonymous Coward · 2017-07-27 10:29 · Score: 5, Funny

They edited some embryos to remove defective genetic defects. Two healthy white babies were successfully delivered 9 months later. Parents Tyvek and Ledasha Washington were happy with the outcome since it allowed them to have children who are more likely to succeed despite their parents' elevated melanin levels.
1. Re:Confirmed... I read the article by Anonymous Coward · 2017-07-27 11:13 · Score: 0
  
  At first I was like wait no white people would be named Tyvek or Ledasha, and then I finished reading and lol'd.
  CAPTCHA: whiter
2. Re:Confirmed... I read the article by Anonymous Coward · 2017-07-28 00:04 · Score: 0
  
  Tyvek is clearly a Vulcan name, so their inter-species children should have impressive logical abilities and a great change of doing great things in this world. Pointy ears can be edited out.
3. Re:Confirmed... I read the article by Anonymous Coward · 2017-07-28 07:40 · Score: 0
  
  I'm still trying to parse
  
  defective genetic defects
  To determine if the genes work or not.
4. Re:Confirmed... I read the article by RespekMyAthorati · 2017-07-28 16:14 · Score: 1
  
  since it allowed them to have children who are more likely to succeed despite their parents' elevated melanin levels.
  And much less likely to be shot by a cop.
5. Re:Confirmed... I read the article by Anonymous Coward · 2017-07-29 18:57 · Score: 0
  
  Because they're much less likely to commit violent crime.
Both Sides? by darkain · 2017-07-27 10:30 · Score: 2, Interesting

On one hand, we're creating genetically modified super-humans. On the other hand, we're also creating AI fueled human killing drones.
World War III sure is looking to be pretty freggin awesome!
1. Re:Both Sides? by Hognoxious · 2017-07-27 10:43 · Score: 1
  
  Certainly worth getting a popcorn machine. Do you think neutrality will be an option?
  
  --
  Confucius say, "Find worm in apple - bad. Find half a worm - worse."
2. Re:Both Sides? by Anonymous Coward · 2017-07-27 10:54 · Score: 0
  
  Certainly worth getting a popcorn machine. Do you think neutrality will be an option?
  What, net neutrality?
Edit? by Sperbels · 2017-07-27 10:37 · Score: 2

So 'edit' is the euphemism we're using for genetic engineering now?
1. Re: Edit? by Anonymous Coward · 2017-07-27 11:20 · Score: 0
  
  Well, you don't engineer source code. You edit, or change it. DNA is biological source code.
2. Re:Edit? by quenda · 2017-07-27 16:16 · Score: 1
  
  So 'edit' is the euphemism we're using for genetic engineering now?
  No. It refers to a specific technique of genetic engineering.
  What part of "clustered regularly interspaced short palindromic repeats" don't you understand?
3. Re:Edit? by Anonymous Coward · 2017-07-27 18:52 · Score: 0
  
  Editing code is exactly what they did. But let's call it hacking, sounds cooler.
4. Re:Edit? by m.alessandrini · 2017-07-27 19:16 · Score: 1
  
  I can't help figuring the scientists using the DNA machine, and the software interface having a "Edit" menu, with Copy, Cut, Paste, Undo, Redo, ...
Re:INB4 all the fundie bullshit by Anonymous Coward · 2017-07-27 10:44 · Score: 0

Funny thing is that the part of the world that thinks abuse and pedophilia are OK is also the part of the world that opposes genetic engineering.
The US is going to go around removing genetic diseases and making people healthier. I have no doubt, though, that while the first objections will come from the religious and anti-science freaks, the next objections will come from the Leftists that will object at people getting healthier if not everyone can afford it.
Just Wondering by NEDHead · 2017-07-27 10:45 · Score: 0

Is it too late to fix Trump?
1. Re:Just Wondering by Anonymous Coward · 2017-07-27 11:43 · Score: 0
  
  That ticket has been marked resolved: no change necessary.
  The other ticket, specifically regarding you, has been marked closed: not fixable.
  I had considered marking it as "unable to reproduce" but there's a slim chance that two liberal weirdos identifying as any of the umpteen-hundred modern genders, given that many of whom are sexual deviants, might turn out to be biologically male and biologically female and make one. And you just might be in one of those pairs some day. Ultimately though, you'll still be blind fool hence my reason for closing the ticket.
2. Re:Just Wondering by NEDHead · 2017-07-27 12:28 · Score: 1
  
  How sad to be you
3. Re:Just Wondering by ChrisMaple · 2017-07-27 15:01 · Score: 0
  
  What are your accomplishments and abilities that make you better than Trump?
  
  --
  Contribute to civilization: ari.aynrand.org/donate
4. Re:Just Wondering by NEDHead · 2017-07-27 15:32 · Score: 1
  
  Well, for starters: I don't abuse women; I don't cheat on my wife; I am not a narcissistic asshole; I am concerned about the welfare of others; I am concerned about the health of our planet; I know science from fiction; and I don't lie.
  And yes, I have a successful career.
5. Re:Just Wondering by PoopJuggler · 2017-07-28 02:42 · Score: 1
  
  Even my kid's pet hamster is better than Trump, although they are the same color.
Re:INB4 all the fundie bullshit by iggymanz · 2017-07-27 10:50 · Score: 1

the land of breast augmentation and facelifts and pec & butt implants is going to use genetic engineering only to make people healthier. yeah right, anon.
So... by DontBeAMoran · 2017-07-27 10:53 · Score: 0

How long until real-life catgirls? Or all women with a C-cup chest size as the minimum?
Or all blondes with blue eyes? I think someone was fixated on that a few decades ago and it didn't turn out very well.

--
#DeleteFacebook
1. Re:So... by cyn1c77 · 2017-07-27 11:30 · Score: 3, Insightful
  
  How long until real-life catgirls? Or all women with a C-cup chest size as the minimum?
  Or all blondes with blue eyes? I think someone was fixated on that a few decades ago and it didn't turn out very well.
  Why does it have to be about gratuitous cosmetic crap? People can already get plastic surgery, they don't need genetic modifications to look good if so inclined.
  But what about no sickle cell anemia or cystic fibrosis? What about improving the human genome in a voluntary way without committing genocide?
  Dream a little bigger than chest size! Not everyone like C-cups and catgirls, but no one likes to die young.
  And given that some people won't even take vaccines, which have been around for at least 200 years (?), I think it's safe to say that there is no danger or the whole population immediately undergoing genetic modifications.
2. Re:So... by Anonymous Coward · 2017-07-27 11:55 · Score: 0
  
  My guess is that the catgirl and tits research will take the lead but as they approach success, the scientists will suddenly switch all their focus to big dicks as fears of inadequacy build. What's the point of catgirls with big tits and blue eyes if they run off with other men?
  They'll also probably put a lot of effort into genetic engineering that will affect late-life subjects (ie. themselves). Otherwise there wouldn't be a point.
Re:Happy Thursday from The Golden Girls! by Anonymous Coward · 2017-07-27 10:54 · Score: 0

With a uid that low, you should be used to this by now. Sad!
Re:INB4 all the fundie bullshit by Anonymous Coward · 2017-07-27 11:13 · Score: 0

You added "only" to that sentence because you knew you aren't smart enough to address what the GP really said and need a strawman to push over.
Re: American embryos edited by a Russian, no surpr by Anonymous Coward · 2017-07-27 11:18 · Score: 0

If their vodka doesn't smell like rubbing alcohol and gives me something besides a headache, I'll try it. It's like getting rum from the Caribbion. It ain't the same anywhere else. I'd trust the Russians to know how to work a potato.
Re: American embryos edited by a Russian, no surp by Anonymous Coward · 2017-07-27 11:18 · Score: 0

Fuck, Caribbean*
But.. by Anonymous Coward · 2017-07-27 11:19 · Score: 1

Are they really defects or stages in evolution? Who decides when a mutation may or may not eventually evolve into a meaningful advance for a species?
1. Re:But.. by Anonymous Coward · 2017-07-27 11:51 · Score: 0
  
  Are they really defects or stages in evolution? Who decides when a mutation may or may not eventually evolve into a meaningful advance for a species?
  As with most things in life, those that do, often do much of the initial deciding as well.
  Those that advocate that we get a practical demonstration of technology first and then later try to figure things out often find themselves on an inconveniently positioned side of history. One might conclude from this that Luddites apparently perform an important role in the long survival of a society, even if their logic is not rational.
  Sometimes just because we can doesn't mean we should. because putting the genie back in the bottle when we later discover it's flaw is generally pretty hard.
2. Re:But.. by ChrisMaple · 2017-07-27 15:05 · Score: 2
  
  Some defects are obvious, leaving their victims dead before they're one year old.
  
  --
  Contribute to civilization: ari.aynrand.org/donate
3. Re:But.. by conquistadorst · 2017-07-28 00:23 · Score: 1
  
  Are they really defects or stages in evolution? Who decides when a mutation may or may not eventually evolve into a meaningful advance for a species?
  Survival and propagation of species drives selection. Something humans are really good at disrupting "naturally" these days.
I saw this in a movie by Anonymous Coward · 2017-07-27 11:21 · Score: 0

https://www.youtube.com/watch?v=wRnSnfiUI54
"Edited" with... by dpiven · 2017-07-27 11:26 · Score: 1

... vi, emacs, dd or notepad?
1. Re:"Edited" with... by Anonymous Coward · 2017-07-27 11:30 · Score: 1
  
  vim and emacs likely both have CRISPR plugins.
2. Re:"Edited" with... by Anonymous Coward · 2017-07-27 21:37 · Score: 0
  
  systemd
Chimera Army uuunnniiiite! by Anonymous Coward · 2017-07-27 11:34 · Score: 0

I'm guessing the point is to make an army of chimeras to run everybody out of Oregon during the eclipse. We are pretty scared down here you know, there isn't even infrastructure in Salem to feed everybody that's going to be here, to speak nothing of water, an army of genetically modified Oregonians at the airport is our only hope!
Had my genetic profile done... apk by Anonymous Coward · 2017-07-27 11:46 · Score: 0

See subject: Actually, my brother did (so might as well be me). The results were interesting & blew a few "family rumors" dispelled too (of having mongol, jew, or ukrainian ancestry).
Turned out I'm "fluoresent NEON white" (lol) being 97.2 PURE polish ancestry (from southern poland near Ukraine) & folks THERE are generally only ~83% so (found that odd but it seconded my father telling me so).
Less than 1% total of Greek, Spanish (no 'dark blood'/moorish traces though - said "Iberian peninsula"), Finnish each (somewhere probably 1,000's of years ago judging by the other number).
* I have NO wish to not be what I already am (as I'm proud to be polish).
So, a "wee bit off-topic" here but not really - after all, it's about genetics!
APK
P.S.=> In the end, lastly: I think a LOT of these folks playing games w/ gene editing will make a LOT of mistakes. Somewhere in my life I heard that the Nazis (mengele iirc) attempted it via breeding. I seem to recall their results were much were like what Mr. Spock told Capt. Kirk about Khan: "Superior ability breeds superior ambition"... I recall (maybe not true, feel free to correct me) that the Nazis ended up w/ psychopaths (super-intelligent but SUPER lack of empathy etc.)... apk
1. Re:Had my genetic profile done... apk by Anonymous Coward · 2017-07-28 05:14 · Score: 0
  
  See subject: Actually, my brother did (so might as well be me). The results were interesting & blew a few "family rumors" dispelled too (of having mongol, jew, or ukrainian ancestry).
  Turned out I'm "fluoresent NEON white" (lol) being 97.2 PURE polish ancestry (from southern poland near Ukraine) & folks THERE are generally only ~83% so (found that odd but it seconded my father telling me so).
  Less than 1% total of Greek, Spanish (no 'dark blood'/moorish traces though - said "Iberian peninsula"), Finnish each (somewhere probably 1,000's of years ago judging by the other number).
  My father had a PhD in 5 fields (including biology), taught biology at the university level, and was a professional consultant. I do not have my dad's credentials, but I remember many dinner table conversations. With every generation going back, you lose 50% of chromosome genetic information from any given ancestor (mtDNA is even worse; it's a straight female line, meaning a single female ancestor for each generation). It may be that you have Jewish ancestry, but genes disappeared in your brother. I know I'm part Blackfoot Indian, but it was so long ago I don't have the genetic markers.
  In simple terms I'm roughly 50% English, 25% Swedish, and 25% Scottish. Looking at actual proven lines gets more nuanced with traces of Italian, Spanish, Portuguese, native American, French, etc. Family folklore and unproven lines includes Jews.
Re:INB4 all the fundie bullshit by ShanghaiBill · 2017-07-27 11:58 · Score: 0

Religious extremism has been linked to several genes. So the GMO corporations could surreptitiously edit those genes to eliminate resistance to their other products.
Coming soon to a test tube near you... by Anonymous Coward · 2017-07-27 15:02 · Score: 0

...fetuses without the genetic defect the defect that causes non-blond hair, the defect that causes non-blue eyes, and that causes non-white skin. It's a shame that we didn't have this ability in the 1930's. (Come on, you know that's where this will go.)
1. Re:Coming soon to a test tube near you... by physburn · 2017-07-27 22:17 · Score: 1
  
  If we could get get rid of obesity, my eyes would feel better, and people would live longer.
Re:INB4 all the fundie bullshit by Applehu+Akbar · 2017-07-27 15:17 · Score: 1

Funny thing is that the part of the world that thinks abuse and pedophilia are OK is also the part of the world that opposes genetic engineering.
You mean Hollywood and Berkeley?
Need more proof. by Anonymous Coward · 2017-07-27 15:38 · Score: 0

You would have to do the same edit a few times and prove that the edit sticks over time.
and see if it is not modified back.
or changes to some thing else. Or maybe down the road things will go all haywire.
Jurassic World... by Anonymous Coward · 2017-07-27 18:16 · Score: 0

Well, they can't get the original DNA, so I'm sure if they paid a "few volunteers" enough they'd be good to go creating the theme park.
The trick is that there's an awful lot we have no clue on vis a vis DNA. Lot's of it appears to do nothing, but... then again, maybe it does something.
Ah, stuff it, let's play with it in the wild. We are clever, we would never let anything bad be created, or make any mistakes. We're scientists!
Obligatory SMBC reference by azrael29a · 2017-07-27 20:45 · Score: 2

Obligatory SMBC comic about gene editing
mandatory editing by Anonymous Coward · 2017-07-27 21:15 · Score: 0

because herd will benefit!
* ability to work longer hours
* eat less or eat food which is easy to produce and thus pollute less, maybe fart less so we can live in more closed space
* remove aggression genes so that there is no voilence and no opposition to goverment
* etc etc....
Maybe we should walk before we run... by Lord+Kano · 2017-07-28 00:59 · Score: 1

Cant we start with sheep, chimpanzees or something before doing this with human embryos?
LK

--
"Hi. This is my friend, Jack Shit, and you don't know him." - Lord Kano
1. Re:Maybe we should walk before we run... by PoopJuggler · 2017-07-28 02:44 · Score: 1
  
  Just what the world needs, super mutant chimpanzees. It's already infested with hairless apes who are too smart for their own good, to much detriment.
Addendum & U.S. Miltary... apk by Anonymous Coward · 2017-07-28 01:59 · Score: 0

See subject: While my brother took his PT tests in Basic Training he set records there (distance running + obstacle course speed of completion etc.) & they "swabbed" the inside of his gums & face cheeks areas.
(I know what this is - it's sampling for genetic engineering test markers for superior physicality (I took genetics in collegiate academia)).
This doesn't surprise me @ all... why?
* Good "jocks" in my family is why. My uncle was a collegiate All-American in basketball (now a dean @ Penn State or @ least last I knew of) & I was pretty ok @ Lacrosse in my time (lettering 1st string freshman & sophomore until physical problems put an end to it for me) http://lemoynedolphins.com/sports/2014/5/29/MLAX_0529144330.aspx/ letter "K" (for a national champion level team from then on out)... & decent students all too.
APK
P.S.=> When they do those 'swabs'? They're looking to USE it for practical manufacture (as in this article's premise) - on a guess here as to why?? Making "super-soldier" Capt. America type soldiers in labs (wouldn't surprise me 1 bit - IF I can think of it, it's been LONG done) - IF that is the case??? It's kind of NICE to know that part of ME is in some "superman" somewhere quite possibly, lol... apk
Re:Happy Thursday from The Golden Girls! by Ann+O'Nymous-Coward · 2017-07-28 04:15 · Score: 1

Not sad at all, I get a genuine giggle out of them. Really. I wasn't being sarcastic with my previous comment, I'm not being sarcastic now. They're fun!
Don't we already know how this is going to turn ou by Ebsolas · 2017-07-28 04:48 · Score: 1

Am I the only one remembering Star Trek? Or what about the Asgards from Stargate? pretty sure that this whole issue about gene editing has been universally regarded as a terrible idea right up there with skynet and grey goo.
We need to start training Blade Runners NOW. by Anonymous Coward · 2017-07-28 05:07 · Score: 0

Replicants will be made soon. We need to start training Blade Runners NOW before it's too late.
Have a bun in the oven? Put it thru the CRISPR by dkman · 2017-07-28 05:45 · Score: 2

n/t

--
I refuse to sign
Universal Soldier by DarthVain · 2017-07-28 05:57 · Score: 1

Meh. I'm not too worried about "Super-Soldiers". Even were you to edit things to make you the most optimal human being, you are still a human being, and are going to be limited by basic biology. Outside of science fiction there are much better ways to kill people and wage wars. A simple bullet will still kill a soldier. Though I guess probably the biggest improvement would be to increase resistance against biological weapons... then again that might have the positive spin off that people stop bothering to make biological weapons as they just aren't as effective. Besides the conventional, chemical, and nuclear ones will all be just as effective against a "super-soldier" as a normal one. Nano-tech is way more scary, but again really only exists in that way in science fiction.
1. Re:Universal Soldier by Anonymous Coward · 2017-07-28 16:32 · Score: 0
  
  Meh. I'm not too worried about "Super-Soldiers".
  "Super-soldiers" are actually far down the list of possible 'evil' uses. You could end up with the entire population genetically "optimized" for their part in society, like strong but not very smart laborers (cheap, self-replicating machines) and others each "customized" to fit their role, and all with a strong genetic predisposition to herd-instinct, lack of more-advanced critical-thinking skills, and an extremely strong predisposition to an instinctual submissiveness to authority. Within a few generations much of humanity could resemble a human ant-colony.
2. Re:Universal Soldier by Anonymous Coward · 2017-07-29 01:31 · Score: 0
  
  What if we also optimize them to be happy with their roles? Would that be a bad thing?
  I have a lot of freedom right now, and I can't say it makes me happy. Restricting my freedom would make me less happy. But if you hacked me so that I was happy with less freedom, instead of always searching for something and never finding it...how would that be bad?
I'll give you an example... apk by Anonymous Coward · 2017-07-28 09:59 · Score: 0

See subject: I live partial color-blindness (red/green, why I'm not designing CPU's) - no electrical allowed in my day. Good vs. camoflague YOU 'SEE' (you don't. To normal eyes you get optically tricked into pattern recog error (I don't & diff. lantern tests I see, you don't too -goes both ways, InfraRed to ULTRAViolet, lol)
That's a trait passed Matriarchal per. My ma kept blaming it on paternal side.
BUT, if I can't build the motor, Ibe "deux ex machina" APK Hosts File Engine 9.0++ SR-7 32/64-bit https://www.google.com/search?hl=en&source=hp&biw=&bih=&q=%22APK+Hosts+File+Engine%22+and+%22start64%22&btnG=Google+Search&gbv=1/
* You are claiming 'disappearance'. Wrong. Available possibles mathematically alone never go - no 'introns no junk DNA' epsecially during mRNA recombination.
APK
P.S.=> Got to jet - reprogramming portions of the above & it's THIS now https://www.youtube.com/watch?v=W97xeMZR6Bs/ - easily 30% faste & still not done... apk
Re:INB4 all the fundie bullshit by iggymanz · 2017-07-28 10:30 · Score: 1

Wrong, India and China are fine with abuse of women and children, and they have practiced editing of human genome of embryos. Therefore GP is wrong.
Re:INB4 all the fundie bullshit by iggymanz · 2017-07-28 10:33 · Score: 1

China and India have done genetic engineering on embryos. They are fine with abuse of children and women. Therefore, your first sentence is ignorant and wrong.
The U.S. has large corporations that will use genetic engineering to make designer humans including for military purposes, because there is a market for it. They already have committed all possible crimes to the present date for power and money including making drugs that maim and kill, nothing will stop them from doing evil in the realm of genetic modification.
My first though was, If it was edited on Slashdot by PJ6 · 2017-07-28 12:43 · Score: 1

the baby would be born with a huge Ã(TM) sticking out of its face.