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EPA Approves Release of Bacteria-Carrying Mosquitoes To 20 States (nature.com)

schwit1 writes: The U.S. Environmental Protection Agency (EPA) has approved the use of a common bacterium to kill wild mosquitoes that transmit viruses such as dengue, yellow fever and Zika, Nature's news team has learned. On November 3rd, the agency told biotechnology start-up MosquitoMate that it could release the bacterium Wolbachia pipientis into the environment as a tool against the Asian tiger mosquito (Aedes albopictus). Lab-reared mosquitoes will deliver the bacterium to wild mosquito populations. The decision -- which the EPA has not formally announced -- allows the company, which is based in Lexington, Kentucky, to release the bacteria-infected mosquitoes in 20 U.S. states and Washington DC.

MosquitoMate will rear the Wolbachia-infected A. albopictus mosquitoes in its laboratories, and then sort males from females. Then the laboratory males, which don't bite, will be released at treatment sites. When these males mate with wild females, which do not carry the same strain of Wolbachia, the resulting fertilized eggs don't hatch because the paternal chromosomes do not form properly. The company says that over time, as more of the Wolbachia-infected males are released and breed with the wild partners, the pest population of A. albopictus mosquitoes dwindles. Other insects, including other species of mosquito, are not harmed by the practice, says Stephen Dobson, an entomologist at the University of Kentucky in Lexington and founder of MosquitoMate.

133 comments

  1. A killer gene drive? What could possibly go wrong? by Anonymous Coward · · Score: 1, Funny

    It’s not like bacteria frequently mutate and jump species!

    And this only makes the entire species go completely extinct! Like in that Star Trek Voyager episode. So fuck the moral implications.

    </sarcasm>

    It will be fun times, when it turns out that humanity really is too dumb to live.

    [CAPTCHA: ending]

  2. We still have an EPA? by Anonymous Coward · · Score: 0

    The traitor administration hasn't fully defunded it yet?

  3. Fingers Crossed by Anonymous Coward · · Score: 1

    Our backyards is full of bloody cane toads at this time of year... I hope they get this one right ;)

  4. It will be hilarious ... by Anonymous Coward · · Score: 0

    When you will find out, that the genetic diversity between people in your community of fucktards is bigger than that of your designated scapegoats that you conveniently blame your complete failure in life on, and they kill you before you manage to release them. XD

    Please... go ahead. Maybe it will teach you a lesson. And maybe not. lol

    1. Re:It will be hilarious ... by Anonymous Coward · · Score: 0

      It's true. Black people and white people look exactly the same and there's far more diversity in each group than between groups because between groups there are no differences whatsoever.

      I wonder when you will find out that islam is, in fact, a religion and not an inheritable trait.

  5. Ecofacist Propaganda Agency with another great pla by Anonymous Coward · · Score: 0

    For their next trick, free Ebola sandwiches!

  6. America always has funds for literal genocide! by Anonymous Coward · · Score: 0

    We wouldn't be Real America(TM) without it, now would we?

  7. Re:What else can mosquitoes deliver? by Anonymous Coward · · Score: 0

    This would be so amazing

  8. I'm actually amazed that this works by phantomfive · · Score: 1

    I've read research that this strategy actually works, which is amazing to me.

    There are so many mosquitos, how can they possibly release enough to actually make a difference in the population?

    --
    "First they came for the slanderers and i said nothing."
    1. Re:I'm actually amazed that this works by Anonymous Coward · · Score: 5, Interesting

      (a) because breeding captive mosquitoes is not very difficult (though it's not pain free: mosquitoes require a blood meal to reproduce, which often involves a person sticking his/her arm in the cage)

      (b) because if the "sterile males" are released in the right time and place, they outnumber the wild males, so *most* wild females mate with a sterile male; repeated a few times this can actually wipe out the wild population

      (c) but as far as I know, separating captive males and females is not so easy

      Source: I used to work in a tropical medicine institute (but not directly with any mosquitoes).

    2. Re:I'm actually amazed that this works by aberglas · · Score: 1

      So, if there are 100 billion wild males, how many sterile ones do you need? A metric shit load?

    3. Re:I'm actually amazed that this works by Dog-Cow · · Score: 1

      Unless they force you to go back, too, that plan is pointless.

    4. Re:I'm actually amazed that this works by Anonymous Coward · · Score: 2, Funny

      (c) but as far as I know, separating captive males and females is not so easy

      They should have the male work a full-time job while giving the female stay-at-home mosquito an unlimited wine-budget and a sense of superiority. That usually does it in the species I've observed.

    5. Re:I'm actually amazed that this works by Anonymous Coward · · Score: 0

      One strategy that can easily bring xenocide on the bloodsuckers is to engineer genetic deformity, carried by males, that causes larval demise, but only in females. If eradication of the species proves to be a "oops" moment, then luckily the pests are actually quite easy to reintroduce.

    6. Re:I'm actually amazed that this works by MangoCats · · Score: 2

      It's targeting a specific species of mosquito, I think part of the effectiveness is reducing that species' competitiveness with other species of mosquito that fill the same niche in the environment.

      End result, you'll still get bitten - but hopefully not Dengue.

    7. Re:I'm actually amazed that this works by MangoCats · · Score: 2

      Your tax dollars at work, breeding mosquitoes in the lab by the shit-ton.

    8. Re:I'm actually amazed that this works by gtall · · Score: 2

      Your tax dollars at work, countering mosquito born diseases after they've already infected the populace.

    9. Re:I'm actually amazed that this works by Anonymous Coward · · Score: 1

      (c) but as far as I know, separating captive males and females is not so easy

      Source: I used to work in a tropical medicine institute (but not directly with any mosquitoes).

      Don't know how it's actually done, but since only females bite, all you should have to do is coat an arm with some sticky glue and let nature follow its course.

    10. Re: I'm actually amazed that this works by Anonymous Coward · · Score: 3, Informative

      Compared to treating babies born with microcephelia over their lifetime...seems like a drop in the bucket.

    11. Re:I'm actually amazed that this works by Gr8Apes · · Score: 1

      I'd be fine with reverting the females to non-bloodsucking variety. Leave the males as males that cause further devolution.

      --
      The cesspool just got a check and balance.
    12. Re:I'm actually amazed that this works by Anonymous Coward · · Score: 1

      (a) because breeding captive mosquitoes is not very difficult (though it's not pain free: mosquitoes require a blood meal to reproduce, which often involves a person sticking his/her arm in the cage)

      They don't stick an arm in. They use bladders of blood they hang in the cage.

    13. Re:I'm actually amazed that this works by Impy+the+Impiuos+Imp · · Score: 1

      Separating them via computer and robot seems like a job awaiting someone.

      --
      (-1: Post disagrees with my already-settled worldview) is not a valid mod option.
    14. Re:I'm actually amazed that this works by Anonymous Coward · · Score: 0

      Science! It's about time you did something useful! : )

    15. Re:I'm actually amazed that this works by Anonymous Coward · · Score: 0

      Human blood?

    16. Re:I'm actually amazed that this works by MagicM · · Score: 1

      (c) but as far as I know, separating captive males and females is not so easy

      Since the males don't bite, it sounds like you can rig up a fresh side of pork with some automatic fly-swatters, and just kill the ones that land for lunch.

    17. Re:I'm actually amazed that this works by brianerst · · Score: 2

      My understanding is that they separate them at the larval stage and there is a size difference - basically pour some water through a sieve and one side has females and the other side has males. It's something like 99.9% effective.

    18. Re:I'm actually amazed that this works by chihowa · · Score: 1

      (a) because breeding captive mosquitoes is not very difficult (though it's not pain free: mosquitoes require a blood meal to reproduce, which often involves a person sticking his/her arm in the cage)

      They don't stick an arm in. They use bladders of blood they hang in the cage.

      The technical term for those blood bags is "grad student".

      --
      If you want a vision of the future, imagine a youtube comments section scrolling - forever.
    19. Re:I'm actually amazed that this works by RockDoctor · · Score: 1
      If the diseases in question travel from mosquito to human (well, mammal) and then back to mosquito, but not from human to human, even if the whole population is infected with all of these disease then suppression of the mosquitoes would still be an effective way of clearing the population of these diseases.

      I think that Zika has rare human-human (sexual) transmission. But even that doesn't obviate the validity of the approach.

      --
      Birds are not dinosaur descendants;birds are dinosaurs, for all useful meanings of "birds", "are" and "dinosaurs"
  9. Mosquitos are anoying, but.... by Anonymous Coward · · Score: 2, Insightful

    Weren't we thaught in school not to mess with the ecosystems and let nature run its course? else we might risk exterminating some species by mistake?

    1. Re: Mosquitos are anoying, but.... by Anonymous Coward · · Score: 1

      Mosquitoes are God's creatures. Don't fuck with them.

    2. Re: Mosquitos are anoying, but.... by Nehmo · · Score: 3, Funny

      Mosquitoes are God's creatures. Don't fuck with them.

      The bacterium Wolbachia pipientis is also a creation of our Lord. We are only being a servant of God.

      --
      (||) Nehmo (||)
    3. Re:Mosquitos are anoying, but.... by Anonymous Coward · · Score: 0

      "when wintertime rolls around, the gorillas simply freeze to death."

    4. Re: Mosquitos are anoying, but.... by Anonymous Coward · · Score: 0

      It would be a bit hard to have sex with them.

    5. Re: Mosquitos are anoying, but.... by aberglas · · Score: 1

      The piece of code I just wrote is a creation of the Lord. Including the bugs which are all part of His plan.

    6. Re:Mosquitos are anoying, but.... by Anonymous Coward · · Score: 0

      Tiger mosquitoes are invasive exotics in North America. We are returning the ecosystem to how it was.

    7. Re:Mosquitos are anoying, but.... by Green+Mountain+Bot · · Score: 1

      We're not eliminating the entire biomass that fills that niche - just a particularly nasty, invasive one that spreads disease. Other, native mosquito species will fill the same ecological niche, so the system as a whole will remain intact.

  10. Can we genocide the bastards? by Anonymous Coward · · Score: 0

    If someone figures out how to extinct all mosquitos on Earth, I am totally on their side!

    1. Re: Can we genocide the bastards? by Anonymous Coward · · Score: 0

      That's not too hard (arsenal of cobalt bombs). There's a minor side effect on all other life though.

  11. Re:Ecofacist Propaganda Agency with another great by Custard+Horse · · Score: 4, Funny

    For their next trick, free Ebola sandwiches!

    Is that like Free Mandela tee-shirts?

  12. And how on Earth.... by franzrogar · · Score: 0

    And how on Earth is going the EPA and US to control that such kind of hybrids doesn't invade another countries like Canada or Mexico?

    Or should we, the rest of the World, to just sit and close our mouth with whatever thing they like to do that might fuck our countries? Same as the Paris Climate?

    1. Re:And how on Earth.... by Anonymous Coward · · Score: 0

      Or should we, the rest of the World, to just sit and close our mouth with whatever thing they like to do that might fuck our countries? Same as the Paris Climate?

      Yes, please do. That's exactly what we need, more complacency. Thank you for choosing American Leadership Lines, please come again.

    2. Re:And how on Earth.... by Kiuas · · Score: 4, Insightful

      Or should we, the rest of the World, to just sit and close our mouth with whatever thing they like to do that might fuck our countries? Same as the Paris Climate?

      Wait what? Did you just equate genetically modified species being released into the wild with a non-binding international treaty to curb emissions? Wtf?

      For the Nth time, the Paris climate agreement is non-binding. If for whatever reason your country does not care about the global climate, you're entirely free to ignore the Paris goals, shut your eyes and keep burning all the oil and the coal you want. There are no sanctions in the treaty for countries that do not meet their goals.

      The point of the Paris agreement is to try to get everyone to do what they can to slow down the rate of emissions (and hence warming) to a point where the consequences are more manageable. The point is precisely to try to make sure nations don't get fucked by massive climatic changes.

      Comparing such a project, which has a well understood basis in natural science (the greenhouse effect has been well understood for over a century and is demonstrable in a lab) and is based on the voluntary co-operation of nations for the common good of everyone (just like the closing of the hole in the ozone layer, which was also achieved by an international consensus and realization that continuation of past practices would have lead to serious harm for everyone) to an experiment where a single nation starts to release genetically modified insects is just plain dumb. We know that reducing emissions is good for everyone in the mid to long term, and we know this for a fact. We don't know that releasing genetically modified mosquitoes into the wild will not have significant adverse effects.

      I understand that this kind of strawman where the Paris treaty is seen as some kind of NWO tool to control what nations can do flies on facebook & al where people get their news from mainly reading headlines of blogposts, but I seriously expect people on this site to have a modicum more of insight into what the treaty actually says before going overboard with the tinfoilhat level of crazy.

      --
      "It is the business of the future to be dangerous" -Alfred North Whitehead
    3. Re:And how on Earth.... by Anonymous Coward · · Score: 0

      We can only promise a quick and painless death, for those who can afford it.

      Sit tight.

    4. Re:And how on Earth.... by PoopJuggler · · Score: 1

      Binding or not, it is wrong of us to not participate.

    5. Re:And how on Earth.... by Anonymous Coward · · Score: 0

      You mean participating by exceeding the requirements that were to be placed on us?

      Oh no.. you don't mean doing anything about climate change. You mean virtual signaling about climate change.

    6. Re:And how on Earth.... by be951 · · Score: 4, Informative

      how on Earth is going the EPA and US to control that such kind of hybrids

      Well, first of all, these are not "hybrids". They are just regular mosquitoes carrying a bacteria that regularly infects mosquitoes already. So, done?

      doesn't invade another countries like Canada or Mexico?

      What the bacteria does is make the male mosquito sterile, so that when he mates with a female in the wild, instead of producing thousands of new mosquitoes they just make thousands of eggs that don't develop. I'm pretty sure we don't have to worry about the eggs migrating to other countries. And since male mosquitoes (the only ones being infected and released) only live about ten days, the risk of them travelling across borders seems fairly small. And if they do, their tenancy as illegal aliens of other countries will be quite short-lived. And, since the treatment they receive sterilizes them, they will have no foreign-born offspring disrupting the existing mosquito populations of other countries, taking their jobs, getting on mosquito welfare, or whatever.

    7. Re:And how on Earth.... by Anonymous Coward · · Score: 0

      how on Earth is going the EPA and US to control that such kind of hybrids

      Well, first of all, these are not "hybrids". They are just regular mosquitoes carrying a bacteria that regularly infects mosquitoes already. So, done?

      doesn't invade another countries like Canada or Mexico?

      What the bacteria does is make the male mosquito sterile, so that when he mates with a female in the wild, instead of producing thousands of new mosquitoes they just make thousands of eggs that don't develop. I'm pretty sure we don't have to worry about the eggs migrating to other countries. And since male mosquitoes (the only ones being infected and released) only live about ten days, the risk of them travelling across borders seems fairly small. And if they do, their tenancy as illegal aliens of other countries will be quite short-lived. And, since the treatment they receive sterilizes them, they will have no foreign-born offspring disrupting the existing mosquito populations of other countries, taking their jobs, getting on mosquito welfare, or whatever.

      +5 nutshell

    8. Re:And how on Earth.... by franzrogar · · Score: 1

      Quote: "And, since the treatment they receive sterilizes them, ..."

      Are you sure? I mean, are you SCIENTIFICALLY sure about that point?

      Let's see some scenearios I'm sure they have taken into account (pun intended):

      1) Mosquitoes infected that ain't sterile after all.
      2) Interspecies newborns that might became bacteria-proof (think like horse + donkey = mule). This mosquito+bacteria + another species of mosquito from other Country might create another thing that hasn't been studies and might even create much much worse scenario
      3) Etc.

      That's why in Europe is not allowed to sell GMOs and in EEUU it is, because there's no study of side-effects. (Like when an USA University proposed, seriously, to launch an umbrella into space to reduce global warming... Â_Â )

    9. Re:And how on Earth.... by be951 · · Score: 1

      Are you sure? I mean, are you SCIENTIFICALLY sure about that point?

      From TFA: "Using lab-grown mosquitoes to kill mosquito pests has been tested extensively in Brazil in recent years. [emphasis mine]" A number of other tests -- for specifically this method, and similar ones -- are mentioned as well, so I'm going to go with "Yes" in answer to your question.

      I'm not sure why you think this is being approved for widespread use (somewhat anyway. But still limited to areas with temperature and precipitation conditions to areas where it was successfully tested within the U.S.) without adequate testing. It is not as if it is going from concept directly to broad approval.

    10. Re:And how on Earth.... by Anonymous Coward · · Score: 0

      What is the difference between mosquitos and feminists? Male mosquitoes don't bite and female feminists don't suck.

    11. Re:And how on Earth.... by Gussington · · Score: 1

      Quote: "And, since the treatment they receive sterilizes them, ..."

      Are you sure? I mean, are you SCIENTIFICALLY sure about that point?

      I'm not sure, but what I am confident of is that the scientists who do this work for a living know more about it than you or I. And even if they go off half-cocked there are layers and layers of scrutiny and regulations to pull them up.
      So yeah, the place to ask these questions is not here.

  13. Re:What else can mosquitoes deliver? by Anonymous Coward · · Score: 0

    There are white muslims too you know.

  14. Too late for that by Anonymous Coward · · Score: 2, Informative

    The Zika-carrying mosquito is an invasive species in the US, and one that got there because of Human globalization and transport systems. Wiping out that subspecies is to restore balance not disrupt it.

    1. Re:Too late for that by boudie2 · · Score: 1

      That's probably what Indians say about whitey.

  15. Re:A killer gene drive? What could possibly go wro by Anonymous Coward · · Score: 0

    Fish birds and frogs eat mosquito's - so if their food source drops 20% then....
    The companies selling overpriced ineffective mosquito repellent will also be hurt.
    Adolescents who make girl dorms mosquito friendly will get less
    Now if only we can add the bacteria to food outside Mosques to American mozzies

  16. Re:A killer gene drive? What could possibly go wro by Anonymous Coward · · Score: 1

    Not only are the targeted mosqutoes an invasive species, but your ability to read TFS is as offensively poor as your abuse of apostrophes.

  17. This won't end well by Anonymous Coward · · Score: 0

    n/t

  18. Re:A killer gene drive? What could possibly go wro by thereitis · · Score: 2

    By approving to only 20 states, do they really think the mosquitoes will not cross state lines? Or jump to Mexico or Canada? What if a country like N.Korea starts designing and releasing their own organisms in a "F the world" gesture - then will it be seen as a problem?

  19. Re:A killer gene drive? What could possibly go wro by Anonymous Coward · · Score: 0

    Dude, it is males. They don't magically reproduce. The give the bacteria to the females, which can breed offsprings. End of story.

  20. Re:A killer gene drive? What could possibly go wro by thereitis · · Score: 1

    Sounds good on paper. Let's watch and see.

  21. Re: Ecofacist ... --.-- by nospam007 · · Score: 1

    "And for the record: I agree that this plan is utterly insane."

    I disagree. If that was the case, the article obviously would have the whatcouldpossiblygowrong flag.

  22. What could possibly go wrong? by Anonymous Coward · · Score: 0

    This is not going to end well. Nope. Not at all.

    "Think of the children" syndrome is going to kill us all.

  23. Well.. by Anonymous Coward · · Score: 0

    What could possibly go wrong?

  24. Finally! by dHagger · · Score: 5, Informative

    The Wolbachia bacteria already exists naturally in insects all over the world, including several species of mosquitoes. The bacteria inhibits reproduction of viruses like Zika, Dengue and Chikungunya in the mosquito, significantly reducing the risk of spreading the virus. This without using any kind of chemicals or genetic engineering. The World Mosquito Program has more information about Wolbachia: http://www.eliminatedengue.com...

    1. Re:Finally! by Anonymous Coward · · Score: 0

      Serious question: Can we produce mass quantities of Wolbachia and simply spray it where ever mosquitoes are found? The process of producing male only infected mosquitoes in the lab sounds immensely complicated and expensive by comparison.

      Second, nature always finds a way. Surely there will be mosquitoes found with a natural resistance to Wolbachia. Just how long will this method be useful until a whole new variation of Wolbachia resistant mosquitoes take back the niche?

  25. These comments are terrible by GrumpySteen · · Score: 5, Insightful

    The bacteria they're using already exists in nature and already infects mosquitoes. Nothing is being released that isn't already out there. All this conjecture about genetically modified organisms, hybrids, extinction, jumping species, etc. is just knee-jerk fear-mongering by people who have no clue what they're talking about.

    1. Re:These comments are terrible by burtosis · · Score: 4, Funny

      Ok, so you agree this can and will start a zombie apocalypse, that's all I needed to hear. Time to top off those ammo bins.

    2. Re:These comments are terrible by gtall · · Score: 1

      Zombie mosquitoes? Now there is a horror flick.

    3. Re:These comments are terrible by Anonymous Coward · · Score: 0

      Right.

      No need to worry about mosquitos carrying any human-harmful diseases. It's not as if that the freaking REASON this is being done in the first place.

      1) Take a bacteria that occurs "naturally" in a population
      2) Create more instances of that bacteria and infect the host as a population control
      3) Watch the increased bacteria population create more mutations (since there are more chances of mutation there WILL be more mutations)
      4) Apply Law Of Unintended Consequences liberally.

      Yeah. I'm totally convinced. Nothing Could Possibly Go Wrong.

    4. Re:These comments are terrible by Ranbot · · Score: 2

      The racist comments are terrible too... That and what you said are the reason no one with actual technical knowledge of a subject posts in Slashdot forums anymore.

    5. Re:These comments are terrible by PoopJuggler · · Score: 1

      So because something exists in nature, humans are incapable of using that thing to disrupt delicate ecosystem balances or create unnatural combinations of that thing with other things that could, in turn, take a path that was unforeseen by the god-like humans who have a perfect record of predicting the outcomes of their machinations in every chaotic system imaginable?

    6. Re:These comments are terrible by Anonymous Coward · · Score: 0

      They suck your brains.

    7. Re:These comments are terrible by dunkelfalke · · Score: 1
      --
      "It's such a fine line between stupid and clever" -- David St. Hubbins, Spinal Tap
    8. Re:These comments are terrible by Ranbot · · Score: 1

      "Zoombies" and "Zombeavers" are actual movies about zombie animals in a zoo and beavers, respectively... Zomsquitoes doesn't sound too far out there in comparison.

    9. Re:These comments are terrible by Anonymous Coward · · Score: 0

      The worst that could happen is that we inadvertently breed a population of mosquitoes that are immune to this bacteria. For that to happen, there need to be enough mosquitoes remaining after this treatment to create a viable population, or the resistant mosquitoes will not be able to find mates to reproduce with.

      Should the worst happen, we will just need to find another way to deal with this mosquito problem. But the worst outcome is in no way a catastrophe, it merely leaves us back where we started.

    10. Re:These comments are terrible by ZZZaphod · · Score: 1

      That statement is incorrect. If, and I'm paraphrasing to make the point, 'we are introducing nothing different', then in fact, we could not expect any change. But, in fact, we are releasing something that is not already out there, and hoping that we like the changes it makes. If I may give words to the thing that you see stuck in our brother's craw, it is: We know that complex systems are complex. We know that we have been, and continue to be surprised by the interactions of complex systems and even moreso by the reactions of complex systems to our intervention. This is true even when we make a careful study of them beforehand. To describe a bit further, the vitriol you hear grows from long lived frustration. From living with the consequences of a lineage of men in white coats who think it their right to make choices that may hurt or harm hundreds, thousands or millions of their brothers. This vitriol is exasperated by a history of excuses and weak apologies as to how the suffering is noble, for it was for the cause of progress that he and his kin did suffer. In the nation I was born, we have a quaint notion that men are created equal, and that my right to life and prosperity and may never infringe upon my fellow countrymen. There, every man has a right to conduct grand, sweeping experiments - on himself, and his family, and his land. And then when he has proven the efficacy and safety of his progress, can his countryman, choose to follow suit. Although it ought not be, a mans confidence is independent of his understanding.

  26. Re:Ecofacist Propaganda Agency with another great by Hal_Porter · · Score: 1

    Free Palestine *

    * Offer only valid with the purchase of one Palestine at full price.

    --
    echo -e 'global _start\n _start:\n mov eax, 2\n int 80h\n jmp _start' > a.asm; nasm a.asm -f elf; ld a.o -o a;
  27. Re:What else can mosquitoes deliver? by Anonymous Coward · · Score: 0

    CIA/Blackwater do not need EPA approval. How do you know this has not already happened?

  28. Have we learned nothing... by Ragnarok89 · · Score: 1

    from Jurassic Park?

    Life... will find a way.

  29. but... by Kludge · · Score: 1

    Do mosquito females only mate with one male?
    I ask because if mosquitoes are like cats or humans who mate with many males, they would end up with offspring even if most of the males are shooting blanks.

  30. One thing is for certain by cstacy · · Score: 4, Funny

    When these males mate with wild females, which do not carry the same strain of Wolbachia, the resulting fertilized eggs don't hatch because the paternal chromosomes do not form properly.

    Except for the ones that do form. One thing is for certain: there is no stopping mutant DNA; the mosquitos will soon be here. And I for one welcome our new insect overlords. I’d like to remind them that as a trusted Slashdot moderator, I can be helpful in rounding up others to toil in their underground anti-DEET research labs.

  31. Reading Comprehension Fail by coinreturn · · Score: 3, Insightful

    There are no genetically-modified mosquitoes here. They are infected with a naturally-occurring bacterium. Please reduce the size of your tinfoil wardrobe.

    1. Re:Reading Comprehension Fail by Thirty4 · · Score: 2

      In Brazil they are using genetically-modified mosquitoes. FTA - "Using lab-grown mosquitoes to kill mosquito pests has been tested extensively in Brazil in recent years. The country has allowed large-scale releases of such mosquitoes in response to an epidemic of the Zika virus that began in 2015. Zika is a mosquito-borne virus that has been linked to severe birth defects, such as abnormally small heads — a condition known as microcephaly. Aedes aegypti mosquitoes are thought to be the primary vector for the virus. One type of mosquito being tested in Brazil is a genetically modified variety of A. aegypti developed by Oxitec in Milton, UK. When the modified male mosquitoes mate with wild females, they pass a lethal gene on to any progeny."

    2. Re:Reading Comprehension Fail by Anonymous Coward · · Score: 0

      Correction:

      They are artificially infected with a naturally-occurring bacterium.

      That is people are going to be doing something by their own decision that occurs naturally through the laws of nature.

      man the laws of nature in many ways

      It's not the same thing. Please expand the openness of your mind and reduce your use of tin foil wardrobe jokes. thx :P

    3. Re:Reading Comprehension Fail by Anonymous Coward · · Score: 0

      that's supposed to read: man [less than symbol] the laws of nature in many ways.

      Furthermore because man is fallible. The laws of nature are not.

      And unlike man, nature can be vicious as f*ck when she gives consequences, as is extremely obvious I think.

  32. Re:A killer gene drive? What could possibly go wro by Anonymous Coward · · Score: 0

    We don't see many Aedes albopictus in Minnesota, nor are we likely to after the mosquitoes are released in those twenty states. I think they don't like winter.

    We do have plenty of other mosquitoes that are incredibly aggravating, however, and in the cities bacteria is routinely dumped into low-lying marshes in the spring to eat the mosquito larvae before or as they hatch.

  33. Test it in DC first by Anonymous Coward · · Score: 0

    I say we release these in Washington DC first and then wait awhile and see what happens. If, after a couple of weeks, everyone there is okay (as in "normal") then they can release the mosquitoes in the other states. But, if the people in DC just walk around making nonsensical statements, like "You can keep your doctor!" and "It's not a tax cut for the rich!', then we destroy the remaining stock.

  34. Re: A killer gene drive? What could possibly go wr by Anonymous Coward · · Score: 0

    I posit that the poster is not actually in the USA and is instead trying to make a joke... but failing miserably.

  35. Re: A killer gene drive? What could possibly go wr by Anonymous Coward · · Score: 0

    Not sure if you are trolling, but in case you are not. Cold kills the buggers, so no need for all states. Also no need to release them in states where there is no problem.

  36. Re: A killer gene drive? What could possibly go wr by Anonymous Coward · · Score: 0

    What's better, a physical wall or an organic wall that can grow and shrink accordingly? Think about it, though the bacteria is specifically for the Tiger Mosquito, just like easter eggs in software there could be a specific pathogen which reacts with water not treated in the US...not anything super bad, but enough to make people crossing the boarder to think twice...just saying that it could happen...it's certainly plausible.

  37. Genetics 101 Question by CodeHog · · Score: 2

    Wouldn't this strengthen the population that carries the viruses by eliminating the weaker carries, i.e. breeding out the weak and re-enforcing the stronger ones? I'm not a biologist or geneticist

    --
    Fat, drunk, and stupid is no way to go through life, son.
    1. Re:Genetics 101 Question by Anonymous Coward · · Score: 0

      Same thing has happened with pesticides and herbicides. Those immune to the introduces chemical (bacteria in this case) remain, while those not immune are wiped out. Once that shift occurs, the immune population slowly increases to take over for those that weren't immune.

      Do we want super mosquitoes? Because this is how we get super mosquitoes.

    2. Re:Genetics 101 Question by Anonymous Coward · · Score: 0

      This is a similar model to the eradication of the primary screw-worm fly or Cochliomyia hominovorax. Due to an abundance of infertile males, over time, the various populations will decrease, to the point where normal mating males are few and far between.

    3. Re:Genetics 101 Question by bahwi · · Score: 1

      Yes, but resistances are best seen as cycles. Many crop plants go through 10-20 year cycles due to various diseases. As plants are distributed immune to a certain disease another eventually comes along, and then disease resistance for that is prioritized. Maintaining an immunity has costs associated with it, so they don't last a long time.

      Also, disease resistant ones may not be "stronger" except in this aspect, it could be linked to a weaker trait, or multiple traits, good, bad, and mostly neutral, but that is determined based on other factors and environment.

    4. Re:Genetics 101 Question by Gussington · · Score: 1

      Wouldn't this strengthen the population that carries the viruses by eliminating the weaker carries, i.e. breeding out the weak and re-enforcing the stronger ones? I'm not a biologist or geneticist

      Only if they survive. For millions of already extinct species this didn't happen, so don't bet the house on 'life always finds a way' bullshit.

  38. Re:A killer gene drive? What could possibly go wro by Anonymous Coward · · Score: 1

    This shit is literally like 50 years old. The science is settled. Even the alarmist EPA couldn't find anything wrong with it.

  39. Re: A killer gene drive? What could possibly go wr by Anonymous Coward · · Score: 0

    Not sure if you're just retarded, but cold states have short but brutal mosquito seasons.

    I'm from the south originally but I've never seen mosquitoes as bad as in areas of North Dakota, Ontario, or Alaska.

  40. Bubonic plague already exists in nature, too by Anonymous Coward · · Score: 0

    If someone proposed releasing extra prairie dogs infected with bubonic plague, the logic that such infected animals already exist in nature would not be a satisfactory defense against concerns about increasing human risk.

    "Nature red in tooth in claw..." just because something is natural says nothing about its safety.

  41. Re:A killer gene drive? What could possibly go wro by Ol+Olsoc · · Score: 5, Informative

    By approving to only 20 states, do they really think the mosquitoes will not cross state lines? Or jump to Mexico or Canada? What if a country like N.Korea starts designing and releasing their own organisms in a "F the world" gesture - then will it be seen as a problem?

    I don't know that the concept is to have strict geographic borders. Any borders will be very fuzzy. But the highly focused control methods are not new. Bacillus thuringiensis I is also used to control Mosquitoes. And it does a great job, killing the larvae of just the mosquitoes (also fungus gnat and blackfly larvae) but that's it. In the pond in my backyard, we use it, and doesn't bother the frogs or fish one bit.

    Bacillus thuringiensis K a version of the bacteria that goes after Gypsy moths. And it's approved for "organic" status.

    Both completely natural, not man made and found on beaches.

    And did you know that there are some species of insect that cannot reproduce without Wolbachia, the bacteria in question? It is a very common bacteria, it has the same effect in a male mosquito who picks it up randomly as in a purposely infected one.

    We've learned a lot about pest control, and have gone far beyond early and clumsy efforts. While so many Slashdotters are still stuck in the 1960's Andromeda Strain world, we've been using these highly focused controls for many years. might as well rail on about vaccines.

    tl;dr version. if Wolbachia is a problem, we're screwed already because it's ubiquitous. As for NK pulling some insect borne stunt, its them and everyone else. This isn't rocket surgery.

    --
    The shepherds did so well protecting the flock that the sheep no longer believed that wolves existed.
  42. Re:A killer gene drive? What could possibly go wro by Anonymous Coward · · Score: 0

    Dude, it is males. They don't magically reproduce. The give the bacteria to the females, which can breed offsprings. End of story.

    Dude. Expecting the average slashdot user to know anything about sexual reproduction and how it works is a little foolish don't you think?

  43. Re:A killer gene drive? What could possibly go wro by Anonymous Coward · · Score: 0

    Except that the EPA is no longer alarmist and openly hostile towards science.

  44. the uneducated masses stir in fear by Anonymous Coward · · Score: 1

    My favorite comments thus far have been ones from people with clearly no understanding of biology or pathology. Would you wet your pants in your chair if I told you this isn't the first time a strategy like this has been employed? Not specifically with the mosquito, or any particular species thereof, but with many invasive species of plants, such as cheatgrass:

    https://blog.nature.org/science/2016/09/07/attacking-invasive-cheatgrass-root-soil-microbes-biocontrol-sage/

    and fish:

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333861/

    This is not under-explored science, nor is it novel. Read a book (or a publication) once in a while instead of buzzfeed and you'd be surprised to learn what we actually know how to do with regard to ecosystem modification.

  45. Re:A killer gene drive? What could possibly go wro by Ogive17 · · Score: 3

    Well - 1st off this species originated in tropical and sub-tropical Asia.. so the more arid western states probably do not have a mosquito problem to begin with. 2nd, southern states that do not experience prolonged sub-freezing temperatures probably have a much larger rate of infection. That right there condenses the areas that could use this "treatment".

    They are only releasing the mosquitoes with the naturally occurring bacteria, they aren't really genetically modified. Think of it more as selective breeding aimed at controlling this aggressive mosquito.

    I just got back from Japan - it wasn't nearly as bad this time but this breed is nasty. My son and I are pin cushions to them.

    --
    "Action without philosophy is a lethal weapon; philosophy without action is worthless."
  46. Don't mess with nature by Anonymous Coward · · Score: 0

    Cane Toads Australia

    1. Re:Don't mess with nature by bahwi · · Score: 1

      And the dodo, T-rex, Brontosauri that roam freely....

      oh wait.

  47. Re: A killer gene drive? What could possibly go wr by Anonymous Coward · · Score: 0

    I think that's the plan, and for you to keep your people in your country too. Don't send them here. Then we'll all be happy.

  48. Natives by Anonymous Coward · · Score: 0

    It's probably what the Native Americans said about the previous Native Americans they got THEIR land from.

    Or do you think that they distributed evenly across the Americas, hung out in their territory and never fought with each other? Read up on the Iroquois.

  49. Re: A killer gene drive? What could possibly go wr by Anonymous Coward · · Score: 0

    This right here. I grew up in Georgia. The Skeeters were bad. Was stationed in Alaska for a while. The skeeters there are far and away the worst I had ever seen. We used 100% deet replant to keep them away.

    https://www.amazon.com/dp/B00TV2J5IG/

  50. Next stage: Vocal Cord Parasites by Anonymous Coward · · Score: 0

    The plan to selectively eliminate population by language spoken has begun...

  51. What could possibly go wrong? by Anonymous Coward · · Score: 0

    What could possibly go wrong????

  52. Naturally occurring by slick7 · · Score: 1

    The basic ingredients of aspartame are naturally occurring. That doesn't mean we should engorge ourselves with it. With the ubiquity of Bisphenol A in the human food chain, sterile "males" will decimate the human race. Thereby giving these insects free reign over this planet. That's how G-d rolls.

    --
    The mind conceives, the body achieves, the spirit manifests.
  53. Re: A killer gene drive? What could possibly go wr by alvinrod · · Score: 2

    Yeah, it's true that Northern states still have mosquitoes. I've even had someone jokingly tell me that the mosquito is even the state bird of Minnesota.

    However, not all mosquito species actually carry the diseases that we'd like to prevent, and some of those species that are carriers don't inhabit northern states or aren't as prevalent on the west coast of the country.

  54. Dear Lord, please . . . by sgt_doom · · Score: 1

    . . . tell me this has absolutely nothing to do with Oxitec or the Gates Foundation, for when Gates Foundation owned Oxitec, and they released those dengue-fighting mosquitoes, every single location experienced an explosion in that Zika virus!

    1. Re: Dear Lord, please . . . by Anonymous Coward · · Score: 0

      Even worse, they just might reproduce handicapped mosquito's. Imagine getting hit by a retarded mosquito with a little helmet!

  55. MEASURED RESPONSE by Anonymous Coward · · Score: 0

    Me and my children are not their lab rats and nature is not their lab.

    The EPA does not legally exist anyway, so any such action on their part will be viewed by many American's a a military attack and will be subject to a measured response.

    Warnings have been given.

  56. AUS by Anonymous Coward · · Score: 0

    two words: cane toad.

  57. Re:A killer gene drive? What could possibly go wro by Anonymous Coward · · Score: 0

    And yet here they are.. doing their job to ensure solid science is applied safely in industry. The world didn't end and the country is operating quite well regardless of what reddit or msnbc might have predicted. Who'da thunk it?

  58. One Side Effect by Anonymous Coward · · Score: 0

    Unfortunately Wolbachia pipientis can cause parthenogenesis which would be a really terrible turn of events. Sending out irradiated males, like we did with the screw fly makes far more sense.

    https://microbewiki.kenyon.edu/index.php/Wolbachia_pipientis

  59. Re: A killer gene drive? What could possibly go wr by Anonymous Coward · · Score: 0

    AC you replied to. I spent 6 years at Fort Rich. Summer deployments to greely were insane for the little bastards. I remember feeling like I had a hundred in each ear canal.

  60. There's an easier way by hyades1 · · Score: 1

    If you want to cut down on the number of blood-sucking parasites in your area, the answer is simple: quit electing them.

    --
    I've calculated my velocity with such exquisite precision that I have no idea where I am.
  61. Re:Ecofacist Propaganda Agency with another great by Anonymous Coward · · Score: 0

    Seems like I can order one from Amazon Warehouse in Used - Acceptable condition, but I just get the feeling it doesn't actually work perfectly.

  62. Re:A killer gene drive? What could possibly go wro by Gussington · · Score: 1

    We've learned a lot about pest control, and have gone far beyond early and clumsy efforts. While so many Slashdotters are still stuck in the 1960's Andromeda Strain world, we've been using these highly focused controls for many years. might as well rail on about vaccines.

    Oh man, I thoroughly enjoyed that post. Good work!

  63. Wolbachia is HUGELY risky by Anonymous Coward · · Score: 0

    False: "Instead of relying on genetic engineering, MosquitoMate infects lab-grown mosquitoes with the common bacterium Wolbachia pipientis, which affects mosquitoes but not animals or humans."

    The 2006 study "Survival of Wolbachia pipientis in Cell-Free Medium" by Rasgon et al. clearly states:

    "Wolbachia infections are maintained by strict maternal inheritance, horizontal transfer events are common over evolutionary time."

    "Wolbachia bacteria were able to survive extracellularly for up to 1 week with no decrease in viability ..."

    And "... were able to reinvade cells and establish stable infections at all time points."

    "The ability of Wolbachia bacteria to survive outside host cells may increase the probability of successful horizontal transfer and the exploitation of new ecological niches." Source: http://aem.asm.org/content/72/11/6934

    The book Immunology, Inflammation and Diseases of the Eye by E. Pearlman and K. Gentil (on page 91) states:

    Wolbachia "is most numerous in the mammalian host compared with the insect stage ... Elevated Wolbachia DNA and even intact Wolbachia are detected in the blood." Further along, it states "within 7 days in the mammalian host, bacteria numbers increased 600-fold." Therefore, it would be fairly easy to add Wolbachia to serologic testing.

    "Wolbachia spp. should be further evaluated as causes of human infection, especially as Wolbachia infection of mosquitoes is increasingly considered to be a tool for interfering with mosquito-borne transmission of human pathogens" (Chen, Dong, et al., 2015). NOTE: Filariodea coxI gene was not found in this case which points to mosquito-to-human transmission. Source: http://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(14)00040-8/fulltext

  64. Re: A killer gene drive? What could possibly go wr by Obfiscator · · Score: 1

    I agree with this. I've lived in central Africa, the upper Midwest US, and a Nordic country.

    The mosquitoes in central Africa (city and rural areas) were definitely less bothersome than summer in rural areas in the other two places. On the other hand, occasionally you come down with malaria.

    --
    "Nothing shocks me. I'm a scientist." -Indiana Jones
  65. the 20 states are by baubo · · Score: 1

    The 20 states are CA, CT, DC, DE, lL, IN, KY, MA, ME, MD, MO, NH, NJ, NV, NY, OH, PA. RI, TN, VT, and WY. (from the document at https://www.regulations.gov/do...)

  66. Re:Ecofacist Propaganda Agency with another great by Anonymous Coward · · Score: 0

    How long before the target mosquitoes adapt to the bacteria, and then become more potent.?

  67. Re:A killer gene drive? What could possibly go wro by Anonymous+Cow+Ward · · Score: 1

    Oh no, not an invasive mosquito species going extinct. Whatever will we do?

    --
    Examine even your most deeply held beliefs. Nobody is always right.
  68. Re: A killer gene drive? What could possibly go wr by Anonymous+Cow+Ward · · Score: 1

    Yep, cold states have intense mosquito seasons, but not with the species they're targeting in this article.

    --
    Examine even your most deeply held beliefs. Nobody is always right.