Slashdot Mirror


Researchers Are Keeping Pig Brains Alive Outside the Body (technologyreview.com)

In a step that could change the definition of death, researchers have restored circulation to the brains of decapitated pigs and kept the reanimated organs alive for as long as 36 hours. From a report: The feat offers scientists a new way to study intact brains in the lab in stunning detail. But it also inaugurates a bizarre new possibility in life extension, should human brains ever be kept on life support outside the body. The work was described on March 28 at a meeting held at the National Institutes of Health to investigate ethical issues arising as US neuroscience centers explore the limits of brain science. During the event, Yale University neuroscientist Nenad Sestan disclosed that a team he leads had experimented on between 100 and 200 pig brains obtained from a slaughterhouse, restoring their circulation using a system of pumps, heaters, and bags of artificial blood warmed to body temperature.

89 of 150 comments (clear)

  1. Pure filth and evil by Anonymous Coward · · Score: 5, Insightful

    This type of experimentation is absolutely evil. This should not be done, even to animals. This is possibly the cruelest thing I have ever heard. Leave it to human beings to invent something that's even worse than death. Because killing isn't bad enough, we need to invent a way to put things into a literal living hell.

    1. Re:Pure filth and evil by sinij · · Score: 4, Insightful

      Yes, this is likely very cruel to pigs if they ever regain consciousness. Which is not given. This will also help treat trauma and organ failure patients and will save human lives.

    2. Re:Pure filth and evil by sinij · · Score: 5, Informative
      Reading TFA:

      Sestan says the organs produce a flat brain wave equivalent to a comatose state

      So no, pig brains were not feeling. They were effectively shut down.

    3. Re: Pure filth and evil by Anonymous Coward · · Score: 1

      Bu, but, butt....

      BACON!!!!!1!

    4. Re:Pure filth and evil by SJMage · · Score: 2

      As much as I understand your exasperation, the usage of homophobic slurs inexcusable. You don't fight against oppression by perpetuating oppression against other victimized groups.

    5. Re:Pure filth and evil by Oswald+McWeany · · Score: 4, Funny

      Yes, this is likely very cruel to pigs if they ever regain consciousness. Which is not given. This will also help treat trauma and organ failure patients and will save human lives.

      I'm not falling for that. I saw The man with 2 brains. I learnt my lesson from that- I know where that leads. Steve Martin does make documentaries right?

      --
      "That's the way to do it" - Punch
    6. Re:Pure filth and evil by iggymanz · · Score: 1

      wrong, brains were from a slaughterhouse that transform pigs into that highest and most noble achievement of being bacon, ham, chops and pork tenderloin. Brains tacos are a thing in some places, but I doubt a couple hundred brains missing from the market inconvenienced any mexicans.

    7. Re:Pure filth and evil by Anonymous Coward · · Score: 1

      Reading TFA:

      Sestan says the organs produce a flat brain wave equivalent to a comatose state

      So no, pig brains were not feeling. They were effectively shut down.

      So you're saying a Futurama Trump head in a jar is right around the corner?

    8. Re:Pure filth and evil by Anonymous Coward · · Score: 1

      Hahaha, you must be new to the neoliberal agenda. Make tolerance intolerant again, etc etc.

    9. Re:Pure filth and evil by Joce640k · · Score: 1

      save human lives.

      Good luck putting it back into a living human body...

      --
      No sig today...
    10. Re:Pure filth and evil by NicknameUnavailable · · Score: 1

      I agree, and I'm of the type to believe nature exists to serve us and that virtually any form of GM is perfectly acceptable on a moral basis. This is just torture, the best potential outcome of which is a means to control the minds of people. It ranks up there with sociology and psychology on the evil scale because even the best outcome is absolutely horrible while the other outcomes are just more horrible.

    11. Re:Pure filth and evil by NicknameUnavailable · · Score: 1

      Bacon isn't immoral - the slaughter is quick and relatively painless and moreover necessary for our survival, that's just nature, in fact that's significantly more kind than nature. This is evil because it involves taking a thing with some degree of sentience, keeping it in a sensory-deprived state and conscious with no hope of recovery, and just poking it. Think of the screeching monkey brain experiment from the movie Transcendence, the only difference here is that you can't hear the tortured animal's cries because the tech isn't even that advanced yet. Hell, this is more fucked up than Kosher or Halal slaughter where they string the animal up by its feet and slice the throat while letting it drain out over minutes fully conscious thanks to the preferential placement of the brain in regard to reduced blood availability. The thing can't even feel its heart beating, it knows it is fucked and all it can see/feel/hear is nothingness until someone flips the switch seemingly at random to shut it off. This is sick and the "scientists" involved are just would-be psychopathic serial killers without the balls to hunt and torture something more dangerous than an animal.

    12. Re:Pure filth and evil by oic0 · · Score: 1

      Remember too that the brain is just part of a system. Without responses from the rest of the system it fails to feel a lot of different emotions. Stress and fear in particular require a bit of feedback from the rest of you to continue on.

    13. Re:Pure filth and evil by rogoshen1 · · Score: 3, Insightful

      So pretend a person is in a car accident and bleeds out. A procedure like this could be done to preserve the brain while the surgeons repair the wounds..

      Or while waiting on blood transfusion, or a donor organ.

      Your absolutely right, this has no practical application other than pig torture and every doctor's latent desire to emulate Frankenstein.

    14. Re:Pure filth and evil by R3d+M3rcury · · Score: 2
    15. Re: Pure filth and evil by NicknameUnavailable · · Score: 1

      There's nothing wrong with killing an animal for food until we find a better solution (that doesn't turn you into a walking vagina,) that's simply biology, there's a lot wrong with torturing an animal.

    16. Re:Pure filth and evil by sheramil · · Score: 2

      And yet when we talk about extending human lifespan or trying head swap surgery all of a sudden that's against nature and 80 years of life is enough!

      I was wondering, where's that Italian surgeon whose name escapes me, who pops up every six months and announces he's going to do a head swap operation with a different rich client? As I faintly recall, the last one was some Russian oligarch with a terminal illness.

    17. Re: Pure filth and evil by Joce640k · · Score: 1

      Who knows how much physical and mental pain these brains-in-jars are feeling right now?

      --
      No sig today...
    18. Re:Pure filth and evil by Tough+Love · · Score: 1

      So those are brain dead brains?

      --
      When all you have is a hammer, every problem starts to look like a thumb.
    19. Re:Pure filth and evil by Khashishi · · Score: 1

      I don't think it would be that horrible to experience. If they could recover brain function, I assume it would be sort of like dreaming. When your brain is disconnected from the outside world, you start to make up your own reality.

    20. Re: Pure filth and evil by iggymanz · · Score: 1

      I don't bother with a moral framework for what has been natural for humans for millennia, bon appetite!

    21. Re:Pure filth and evil by another_twilight · · Score: 1

      it involves taking a thing with some degree of sentience, keeping it in a sensory-deprived state and conscious

      Were that the case, I'd agree wholeheartedly, but TFA states

      There was no evidence that the disembodied pig brains regained consciousness.

      Later, TFA states

      Sestan now says the organs produce a flat brain wave equivalent to a comatose state

      although that statement is made in the context that they were looking to see if an ex-vivo brain could regain consciousness. Initially they thought they had found evidence of this, then put it down to artifacts in the equipment.

      So, I'm not sure I'd give them a pass just because they failed to take a brain from an animal that has died and restore it to a kind of disembodied consciousness.

      without the balls to hunt and torture something more dangerous than an animal.

      Um, the only way I can get that sentence to parse makes calling someone else psychopathic kind of hypocritical.

    22. Re:Pure filth and evil by arglebargle_xiv · · Score: 1

      Also, what if the police want their brains back? Or do they share one brain among themselves?

    23. Re:Pure filth and evil by rtb61 · · Score: 1

      Ahh, so I see you have never suffered from a headache. You are aware you do not really feel pain in the rest of your body, you feel that pain, in your brain. You nervous system feeds those sensations back to your brain, so only the connections in your brain to that nervous system need to be intact to feel, literally anything, from you body being onfire, to being shredded in a mulching machine, of course anything except probably anything fun. The way to tell if the brain is alive is that it is in fact functioning and not brain dead ie not functioning. So yeah, it sounds pretty cruel and probably quite a questionable experiments. Those brains likely going brain dead as a result of extreme shock, a chemical shut down. Pretty fucking insensitive.

      --
      Chaos - everything, everywhere, everywhen
    24. Re:Pure filth and evil by Keramos · · Score: 1

      Yep. All they gotta do is hook the brains up to twitter and get something at least as insightful as "covfefe" out of them, and BAM! we're in the future.

    25. Re: Pure filth and evil by DanAndDusty · · Score: 1

      The brain doesn't have pain receptors.. However it does process sensations from pain..

      People who have limb amputations often complain of "Phantom Limb Pain" (Yes.. Its googleable)

      So Im glad the flat-line output of these brains does imply no processing, because I gather phantom limb pain is bad, I would hate to think what Phantom Body pain would feel like.

    26. Re:Pure filth and evil by Khashishi · · Score: 1

      It's pure speculation on either of our parts..

    27. Re:Pure filth and evil by alexgieg · · Score: 1

      save human lives

      Someone already mentioned the Nazis, so I give you Unit 731. Experimenting on American POWs helped save human lives!!!, so it was not only perfectly okay, pardoning the researchers was even more so, right? Right?

      --
      Conservatism: (n.) love of the existing evils. Liberalism: (n.) desire to substitute new evils for the existing ones.
    28. Re:Pure filth and evil by david_thornley · · Score: 1

      It doesn't really matter, but Unit 731 "logs" were mostly Chinese. There are some differences, though.

      We routinely kill pigs. My last ham and cheese omelette tasted fine, and I rather suspect it involved an untimely demise for a pig. We don't routinely kill humans, and generally don't eat them afterwards.

      Also, neither the Nazis nor Unit 731 cared a bit about how the subjects felt. (One Unit 731 role was to let Japanese doctors practice battlefield operations, like say amputating a limb, and they thought anesthetic would be a waste of resources.) Modern animal experiments have ethical constraints on them.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
    29. Re:Pure filth and evil by david_thornley · · Score: 1

      Not to mention their pets. The only way to get healthy cats on a vegan diet is to use all parts of the vegan.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
    30. Re:Pure filth and evil by david_thornley · · Score: 1

      Feel free to look through my posting history. You'll notice that I'm not, in fact, right-wing. I find the Democrats as a party to be too right-wing.

      Veganism as a moral stance is stupid. That said, I really don't care in general what other people do to themselves, so I'm not upset with them.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
    31. Re:Pure filth and evil by david_thornley · · Score: 1

      Is the pig brain conscious? I got the impression that the researchers were preventing that, and were verifying with the brain waves.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
    32. Re:Pure filth and evil by alexgieg · · Score: 1

      We routinely kill pigs.

      Killing isn't the problem. The problem is causing pain for long periods. US factory farms are particularly cruel endeavors on that side of the equation, and on the other ethical constraints on animal research provide hardly better living conditions for those used in them. That pain, and the brutality that goes into producing and maintaining it, are the aspects that need corrected, specially because it isn't uncommon for both to "overflow" into how humans themselves get treated by other humans.

      --
      Conservatism: (n.) love of the existing evils. Liberalism: (n.) desire to substitute new evils for the existing ones.
    33. Re: Pure filth and evil by net28573 · · Score: 1

      If anything, the researchers would perform a lobotomy of some sort and focus on keeping the tissues alive and viable outside the body. The pig wouldn't even exist after that point and it wouldn't be able to process any bodily pain either.

      --
      RIP TRICERATOPS, YOU NEVER EXISTED
    34. Re: Pure filth and evil by iggymanz · · Score: 1

      Wasn't aware the soldiers were eating enemy afterwards.

      I'm all for self-defense too and right to bear arms, that's natural and right.

  2. I have no mouth and I must scream? by sl3xd · · Score: 3, Insightful

    That said, there's living tissue and functioning tissue... I'm not sure this is the latter.

    --
    -- Sometimes you have to turn the lights off in order to see.
    1. Re:I have no mouth and I must scream? by hcs_$reboot · · Score: 2

      Hawking's brain was working pretty well.

      --
      Slashdot, fix the reply notifications... You won't get away with it...
    2. Re:I have no mouth and I must scream? by Anonymous Coward · · Score: 1

      The summary makes it sound like they took a dead brain and pumped blood through it. Not at all what the title said. I, of course, didn't read the article.

      But we are looking at the possibility of a future in which a whole new kind of torture, more horrible than any invented before, becomes an actual possibility. Combine tech that keep a brain alive with implants that create a virtual reality for that brain...and you can make the religious myth of "Hell" an experiential reality for any helpless victim you choose.

    3. Re:I have no mouth and I must scream? by david_thornley · · Score: 1

      Humans have already mastered the art of keeping other humans in extreme distress for a long time. Heck, I've heard accounts from people who had large third-degree burns, and that sounds less comfortable than most torture devices.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
  3. Futurama by Anonymous Coward · · Score: 5, Funny

    Already covered the ethical issues of this in detail. Nixons head must not be allowed to take over again!

    1. Re:Futurama by Anonymous Coward · · Score: 5, Funny

      Came for the Futurama reference; leaving satisfied.

    2. Re:Futurama by PolygamousRanchKid+ · · Score: 4, Insightful

      Nixons head must not be allowed to take over again!

      Given another Clinton/Trump choice in 2020 . . . I'll vote for the third party disembodied pig head, instead.

      --
      Schroedinger's Brexit: The UK is both in and out of the EU at the same time!
    3. Re:Futurama by Mike+Van+Pelt · · Score: 3, Insightful

      I'd write in Cthulhu as the lesser evil.

    4. Re:Futurama by neoRUR · · Score: 1

      Next thing you know we will be talking to our meat! (go to 1:24 in video)
      https://www.youtube.com/watch?...

  4. Kramer by XanC · · Score: 4, Funny

    Believe me, somewhere in this hospital the anguished oink of pig-man cries out for help!

  5. Dilbert ... by Anonymous Coward · · Score: 1

    Wow, this weeks Dilbert seems especially relevant now.

  6. Donovan's Brain by magusxxx · · Score: 1

    If people keep repeating the word 'pork', I'm outta here!

    --
    Care killed the cat, but satisfaction brought it back.
  7. Stop making fun of POTUS! by houghi · · Score: 2

    Seriously. This is not funny anymore.

    --
    Don't fight for your country, if your country does not fight for you.
    1. Re:Stop making fun of POTUS! by ilsaloving · · Score: 5, Funny

      What do you mean? We're talking about disembodied comatose pig brains, not.... oh.

    2. Re:Stop making fun of POTUS! by david_thornley · · Score: 1

      While I can intellectually understand the argument that the people who voted for Trump got what they deserved, I don't see that those of us who didn't got what we deserved.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
  8. Next Step: Drones by ghoul · · Score: 1

    No need to create complicated AI chips. Just use brains from convicts.

    --
    **Life is too short to be serious**
    1. Re:Next Step: Drones by AntronArgaiv · · Score: 2

      No need to create complicated AI chips. Just use brains from convicts.

      But, please...not "ABNORMAL" ones

    2. Re:Next Step: Drones by angel'o'sphere · · Score: 1

      A convicted decapitated abnormal Go player - who plays on AI levels - would finally be a challenge for me! /me looks around for his go books

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    3. Re:Next Step: Drones by HiThere · · Score: 3, Interesting

      Cordwainer Smith figured that mouse brains would suffice for many uses. But I think he cheated when letting them understand English. (OTOH, he had the sliced into thin sections and, preserved somehow, not really specified. But they didn't require lots of support equipment. This wasn't the same as his "underpeople", I think I'm remembering from "The Lady that Sailed the Soul".)

      --

      I think we've pushed this "anyone can grow up to be president" thing too far.
  9. Summary missing key detail by Nidi62 · · Score: 4, Insightful
    From TFA(and yes, turning in my slashdot card)

    There was no evidence that the disembodied pig brains regained consciousness. However, in what Sestan termed a “mind-boggling” and “unexpected” result, billions of individual cells in the brains were found to be healthy and capable of normal activity.

    So the brains are still dead. There is no consciousness, no functioning of the brain itself. All this really shows is something that really isn't a surprise: the brain cells don't die right away. Because the neurons are still dead, this is no different than keeping an arm or an organ alive outside the body. It might lead to some improvements with transplants, but until they can actually show renewed neuron activity in the brain, this idea is as dead as a slab of bacon.

    --
    The only thing necessary for evil to triumph is for it to be pitted against a slightly greater evil
    1. Re:Summary missing key detail by Catbeller · · Score: 1

      The brains are being artificially deadened by the blockers in the solution, per the article. They are probably thinking about what happens if they took those out...

      No reason for a brain to die. Supply it with what it needs, and it can stay alive...who know how long. If you can feed the auditory and retinal input, you'd have something that has no haptic reality, but can still think, see, hear. Neural cybernetic links are doable.

      Death as we always define it is nonsense. If the brain is alive, death doesn't come. We let the brain die when the body dies because of traditions so laser-etched into our souls that the body is the person. You don't die when your heart stops. The heart is a pump. You die when your brain dies. Sobering to think that the newly-dead person you are seeing in front of you maintains consciousness for a minute or so, in the dark and quiet we all get to greet at the end.

    2. Re:Summary missing key detail by NoImNotNineVolt · · Score: 1

      until they can actually show renewed neuron activity

      but, as per your own quote...

      billions of individual cells in the brains were found to be healthy and capable of normal activity.

      --
      Chuuch. Preach. Tabernacle.
    3. Re:Summary missing key detail by david_thornley · · Score: 1

      Brains are, in fact, biological, and it isn't clear to me that they'd be immortal if properly taken care of outside the body.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
  10. Care Dog Meets Pee Bear: a SubGenius bedtime Story by spun · · Score: 1, Troll

    (Trust me, it's relevant.)

    (originally published in "Bob's" Big Book of Fables for Sleepy-Heads, Simon & Schuster, 1943)

    Once upon a time!

    Care Dog was strolling along on a bright, sunny Summer's day. Sweet-hearted fellow that he was, he enjoyed the beautiful singing of the birds and the comforting buzz of the bees. He was on the road through Sweet-Wood Forest, with Care-A-Lot town far behind him, when quite suddenly he happened upon Pee Bear, who was sitting right in the middle of the road. That rascally Pee Bear was picking fat gray ticks off of his feces-encrusted sphinctor area, and popping them into his mouth, chewing them with a look of glee.

    "Pee Bear! You shouldn't be picking ticks off your fanny and eating them!" scolded Care Dog, who was naturally concerned for the health of all the animals in the forest.

    "Go fuck yourself ragged, Care Dog... with a big dick, with BIG RED STRAPS!" cursed Pee Bear, who seemed to be in quite a nasty mood. "These fucking shit-ticks are driving me crazy!" He bent over to gnaw feverishly at his own rectum. Urgent little whines of relief mingled with yelps of pain.

    "B-but Pee Bear!" said Care Dog, his feelings hurt. "Those ticks are all covered with your poo-poo! They could be carrying a terrible disease! Why, you might die from eating them!"

    Pee Bear stopped his butt-chewing then, and looked up at Care Dog with an expression of pure hate.

    "Me and everything else in this forest is half dead already, you stupid sap! Look around you, Care Dog! This whole forest is dying, the humans of Realworld Land did it, and there isn't a Jesus-fucking thing anybody's gonna do about it. You and all your precious fellow Cute-A-Lots, and me, and everything else that lives in this forest, we're all going to die. Nothing can stop the living hell on earth that's coming -- not all the rainbows and hearts and flowers and unicorns, and pretty little tick-less baby-faced simpering liberal goody-two-shoes TV stars like you, in the universe! These festering mutated ticks on my anus -- they're but the barest glimpse of the suffering in store for you! Yes, even you, Care Dog! Your "Loving God" is about to abandon you, and your world -- and mine! -- to a fate unimagined in your most unspeakable nightmares. And for what? For nothing! So don't give me your sappy sweetie-weetie CRAP, you pathetic eunuch of a cutesy-putesy pile of shit!!! Now leave me alone and let me deal with this horrible itching in peace! -- if there is such a thing as peace in this fucked world."

    Care Dog was stricken! He didn't know what to say. He knew that Pee Bear only needed a little love and understanding -- but the tormented Bear of the Bathrooms looked as if he would strike him if he said a word!

    What was Care Dog to do?

    But then, upon seeing the big tears welling up in the eyes of the poor Canine of Kindness, Pee Bear got a crafty look in his eye. He hung his head and apologized.

    "Oh, I'm so sorry, Care Dog. Can you forgive me? I'm just been in such a bad mood lately, what with these ticks and vermin eating away at my poor asshole." He smiled his sweetest sad smile at Care Dog, and shuffled his feet bashfully to show that he was sorry.

    Care Dog wiped the tears away and looked up hopefully, "You... you really mean it, Pee Bear?"

    "Sure, Care Dog. In fact, why don't you come closer? There's a present I'd like to give you."

    Trustingly, Care Dog walked towards Pee Bear. In his childlike innocence, he hadn't even noticed that that wily Bear had extended his huge, hideous bear dick from its furry sheath. Its pointed tip glistened with a quivering drop of anticipatory "gleet." The hairy base of it writhed with fleas.

    Care Dog sniffed the air. "Say, do you smell something dead, Pee Bear?" (Care Dog quickly dismissed the ridiculous, primitive urge that always made him want to find any dead thing and roll around on it. That wasn't the kind of thing that polite dogs did!)

    Then he saw that Pee Bear wore a very strange expression. Why was he l

    --
    - None can love freedom heartily, but good men; the rest love not freedom, but license. -- John Milton
  11. The potential implications are staggering by Falconnan · · Score: 5, Insightful

    Admittedly, the article suggests a comatose state. However, imagine being in this state: No sensory input from any normal sources. The potential for the final state of the body to translate into a sensation of pain from any/all possible sources. I understand the goal here, and maybe at some point this would be a viable option. However, to me, this is kind of terrifying. The animal cruelty implications aren't minor, either.

    1. Re:The potential implications are staggering by bigpat · · Score: 3, Insightful

      Of course the ethical point of this is serious. Even if you could achieve human brain transplant. I mean,,,,,,the other host,,,,is or was someone else,,,how do you cope with that, the family sees their love ones walking and talking but with someone else's brain, brings me to Altered Carbon sci-fi series.

      Kind of really scary

      Kinda really scary... but... if we can achieve some sort of economically viable cloning/body growing technology. So say growing a new body costs about the same or less than buying a new car so most people can afford it, then I think that could be on balance a good thing for society and especially for individuals whose bodies become permanently disabled well before "their time".

      I think some aspect of Altered Carbon's view of a potential future are terrifying, especially if the ability to restore life in its fullest is reserved for the wealthy and a token few. We don't want to create a vampire class where the wealthy maintain their wealth and power over others simply by refusing to die while others remain poor simply because they don't live long enough to accumulate relative wealth.

      If economically viable for a great number of people, then the ability to live another lifetime in a younger healthier body could really improve our existence in a variety of ways and people would always retain the option to just to live out their existing natural lifespan and be done with it.

      In some scenarios it could make overpopulation worse, but society needs to adapt to the lower death rates we have already achieved with modern medicine regardless of any radical life extension that would be measured as a couple hundred years. Just random accidents and degradation of the brain itself will still cause attrition, unlike in the fictional Altered Carbon universe where it is a lot harder to die and the biological limitations of the brain are circumvented with a literary device.

      Speaking for myself, I think I could go for another couple rounds of a healthy youthful life.

    2. Re:The potential implications are staggering by swb · · Score: 1

      My guess is what you describe only really works with an Altered Carbon type of device to store brain contents and transfer it to a new brain.

      I'd guess that the surgical complexity to actually move a physical brain between skulls makes it necessary to treat the brain's contents separately from its physical entity.

    3. Re:The potential implications are staggering by h4ck7h3p14n37 · · Score: 2

      I share the same concerns about this type of research. I seem to remember another recent experiment where they grew mice with brains containing some human brain cells. It's not just animals though, what about artificial intelligences?

      Since we can't enter the consciousness of something else, how can we be sure we haven't created something that exists in a state of constant agony?

    4. Re:The potential implications are staggering by HiThere · · Score: 2

      That's not clear. Admittedly my first thought was "This is something new in the way of sensory deprivation!", but on further thought I'm less sure. From what I've heard, people who have recovered from being "locked in" don't report anything dreadful. They just became fuzzy and disconnected. It's as if because they weren't receiving any messages, they just didn't think. They don't seem to have been aware that time was passing.

      --

      I think we've pushed this "anyone can grow up to be president" thing too far.
    5. Re:The potential implications are staggering by drunken_boxer777 · · Score: 2

      Pain is transmitted by a specific kind of neuron called a nociceptor. If they aren't transmitting pain signals, then, if conscious, the brain would not experience pain. That doesn't mean it could relive the final moments over and over in sensory deprivation and experience mental anguish. Not pleasant however you slice it (no pun intended), but that doesn't seem to be the case here. The investigator stated that there was a flat EEG, and we don't have any reason to believe a brain is "thinking" without EEG activity.

      (I realize this anthropomorphizes pigs quite a bit, but the ethical concerns largely focus on translation to humans.)

    6. Re:The potential implications are staggering by Anonymice · · Score: 1

      You're forgetting that those brains need a body. It would neither help the masses, nor affect population levels. Unless the bodies are being artificially grown in their entirety, someone's brain is going to be sacrificed so another can be hosted.

      The only ethical solution here would be for the host to already be brain-dead.

    7. Re:The potential implications are staggering by bigpat · · Score: 1

      My guess is what you describe only really works with an Altered Carbon type of device to store brain contents and transfer it to a new brain.

      I'd guess that the surgical complexity to actually move a physical brain between skulls makes it necessary to treat the brain's contents separately from its physical entity.

      I think you have the notion of complexity backwards. It seems far less complicated to try and connect 31 nerve bundles in the spine and optic nerves than to map out an entire living human brain and try to make a working copy of it. The brain is very very complex. 125 trillion synapses in the cerebral cortex alone and the brain is constantly changing.

      If we can ever get to the point we can repair spinal cord injuries, then we can do brain to body transplants. Somehow mapping the human brain to make an exact working copy might be mathematically impossible. And even if it were possible then it still would just be a copy made over some finite period of time.

    8. Re:The potential implications are staggering by Falconnan · · Score: 1

      Respectfully, this assertion is probably incorrect. Nociceptors are responsible for transmitting data from the body indicating damage, true. However, perception of pain takes place in the brain, and can in fact be experienced without exterior stimulation. Typically this results in some serious pain being experienced despite a lack of damage. Ask amputees. Now, usually, when the system is working it seems that the brain fills in data from multiple sources and derives that there is nothing wrong. However, without data coming in there is no source to double check. If this hypothesis is correct, who knows what you'd experience.

  12. A bit misleading by MerlinTheWizard · · Score: 1

    As far as I got it, they managed to keep the brains "alive" in the sense that cells were getting nutrients through artifical blood flow. There was no sign of any remotely normal functioning of the brains though. So, outside of any ethical considerations, that's still completely pointless.

    One thing to consider is that once a brain is deprived of any afferent information, its ability to function probably declines very quickly. It may be interesting for neural experimentation but that's pretty much it.

    Of course, if any sort of consciousness was kept "alive", that would be something else entirely.

  13. Sweating by Tablizer · · Score: 2

    Must ... Resist ... Trump ... Jokes...

  14. reminds me of the 90's TV show LEXX by FudRucker · · Score: 1

    that dragonfly looking space ship with all those brains in those containers in the back, stanley tweedle was the captain

    --
    Politics is Treachery, Religion is Brainwashing
  15. Somewhere in Heaven... by magusxxx · · Score: 2

    Don Adams looks at Stephen Hawking and says, "Missed it by THAT much."

    --
    Care killed the cat, but satisfaction brought it back.
    1. Re:Somewhere in Heaven... by Tough+Love · · Score: 1

      Don Adams looks at Stephen Hawking and says, "Missed it by THAT much."

      Stephen Hawking pretty much proved that the will to live is nearly limitless, and that a healthy body is only a small part of what we are.

      --
      When all you have is a hammer, every problem starts to look like a thumb.
  16. Brain, brain, brain, what is this brain? by slew · · Score: 1

    Just don't let this technology fall into the hands of the Imorg... Pain and delight may ensue...

  17. Are You Thinking What I'm Thinking? by cstacy · · Score: 1

    This non-kosher headache nightmare will be with me for some time, Pinky.

  18. Are You Thinking What I'm Thinking? by cstacy · · Score: 1

    This non-kosher headache nightmare will be with me for some time, Porky. Errrr, Pinky.

    Thee-a-tha-thee-a-butt That's All, Folks!

  19. anything worth doing is worth militarizing by roc97007 · · Score: 1

    I'd be astonished if someone hadn't wondered if pig brains could pilot a missile.

    --
    Oliver's law of assumed responsibility: If you're seen fixing it, you will be blamed for breaking it.
  20. Re:Care Dog Meets Pee Bear: a SubGenius bedtime St by sheramil · · Score: 1

    I came here to deliberately NOT post a link to that story. With big, red straps!

  21. Old news, russsians did this long ago... by Faw · · Score: 2

    ...and it was all done in the 1950s. Search for Doctor Sergei S. Bryukhonenko.

    Experiments in the Revival of Organisms

    Check the weird stuff in youtube.

  22. I can see the movie now; by Chris+Mattern · · Score: 1

    "They Saved Arnold's Brain"

    1. Re:I can see the movie now; by Tough+Love · · Score: 1

      Only that?

      --
      When all you have is a hammer, every problem starts to look like a thumb.
  23. Experiments in the Revival of Organisms by drunken_boxer777 · · Score: 1

    If you've got 20 minutes, check out this video from Moscow in 1940 showing attempts to keep severed dog heads alive. Even J B S Haldane makes an appearance.

  24. That's amazing. by Cryptimus · · Score: 2

    I had a good look during the recent State of The Union and I couldn't see any mechanical devices whatsoever. They must've really cracked the miniaturization problem.

  25. From the pig's point of view... by Tough+Love · · Score: 1

    From the pig's point of view, being slaughtered and eaten is already pretty much the most horrifying thing imaginable. Supposing that consciousness could be restored, isn't that better than death? What's the issue here? Maybe we shouldn't be killing and eating pigs.

    The big take away for me is, there's no debate at all about whether a pig has consciousness and self awareness. It hasn't always been that way.

    --
    When all you have is a hammer, every problem starts to look like a thumb.
  26. Re:Care Dog Meets Pee Bear: a SubGenius bedtime St by spun · · Score: 1

    It's a story written by Paul Mavrides, you've honestly never heard of the Church of the SubGenius or Bob Dobbs? You should have gotten a copy in your Nerd Starter Pack. Sad, you are missing out on some really good comedy. Here's a link https://www.amazon.com/Book-Su...

    --
    - None can love freedom heartily, but good men; the rest love not freedom, but license. -- John Milton
  27. And I Must Scream by IonOtter · · Score: 1
    --
    [End Of Line]
  28. Biology still remains in the dark age ... by fygment · · Score: 1

    The only way our human understanding of biology has been able to progress has been by the brutalisation of living organisms. While that was understandable centuries ago in the past century (at least) there have been the tools in place for biology to take a more theoretical approach say, the development of mathematical models to explain and simulate living organisms. Yet instead biology has overwhelmingly continued to embrace crass approaches to the study of organisms using modern technology only to persist in the same observation-by-destruction methodology. What is it in the majority of biologists that makes this approach persist, that makes killing organisms or perverse experiments like the subject of this thread acceptable?

    Biology isn't a science until it develops some first principles like say math or physics. Until then it is little more than butterfly collectors, mostly harmless unless you are something they take an interest in ... then your life is forfeit.

    --
    "Consensus" in science is _always_ a political construct.
    1. Re:Biology still remains in the dark age ... by david_thornley · · Score: 1

      Biology is a science. Mathematics isn't. A science is something where we find objective evidence of things, make theories, make tests and observations to try to falsify the theories, and repeat. Mathematics is something where we start with basic assumptions and make deductions from them. It's very useful as an assist in science, but it isn't science.

      Physics doesn't have first principles. It has assumptions and theories. A little over a century ago, space and time were first principles. We now know there is no such thing; they're ways of looking at spacetime. Causality was a first principle. That doesn't turn out to be true on the quantum level.

      Suppose we'd had incredibly powerful computers in 1900, and we programmed them to find physical laws. We wouldn't have relativity. We wouldn't have quantum mechanics. We know far more now, and physicists are still insisting on experiments, because we don't know enough.

      Physics is far simpler than biology. We know a lot less about the fundamental principles of life, if they exist, than the fundamental principles of physics.

      In short, the reason why biologists run experiments is that they have to, in order to learn new things..

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes