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Study Finds Probiotics 'Not As Beneficial For Gut Health As Previously Thought' (theguardian.com)
An anonymous reader quotes a report from The Guardian: The gut microbiome is the sum total of all the micro-organisms living in a person's gut, and has been shown to play a huge role in human health. New research has found probiotics -- usually taken as supplements or in foods such as yoghurt, kimchi or kefir -- can hinder a patient's gut microbiome from returning to normal after a course of antibiotics, and that different people respond to probiotics in dramatically different ways. In the first of two papers published in the journal Cell, researchers performed endoscopies and colonoscopies to sample and study the gut microbiomes of people who took antibiotics before and after probiotic consumption. Another group were given samples of their own gut microbiomes collected before consuming antibiotics. The researchers found the microbiomes of those who had taken the probiotics had suffered a "very severe disturbance." "Once the probiotics had colonized the gut, they completely inhibited the return of the indigenous microbiome which was disrupted during antibiotic treatment," said Eran Elinav, an immunologist at the Weizmann Institute of Science in Israel and lead author on the studies.
The scientists also compared the gut microbiomes of the gut intestinal tract of 25 volunteers with that of their stools. They found that stool bacteria only partially correlated with the microbiomes functioning inside their bodies. "So the fact that we all almost exclusively rely on stool in our microbiome research may not be a reliable way of studying gut microbiome health," said Elinav. In the second paper, the researchers examined the colonization and impact of probiotics on 15 people by sampling within their gastrointestinal tract. They divided the individuals into two groups: one were given a preparation made of 11 strains of very commonly used probiotics and the other were given a placebo. Of those who were given probiotics, he said, "We could group the individuals into two distinct groups: one which resisted the colonisation of the probiotics, and one in which the probiotics colonized the gut and modified the composition of the gut microbiome and the genes of the host individual."
The scientists also compared the gut microbiomes of the gut intestinal tract of 25 volunteers with that of their stools. They found that stool bacteria only partially correlated with the microbiomes functioning inside their bodies. "So the fact that we all almost exclusively rely on stool in our microbiome research may not be a reliable way of studying gut microbiome health," said Elinav. In the second paper, the researchers examined the colonization and impact of probiotics on 15 people by sampling within their gastrointestinal tract. They divided the individuals into two groups: one were given a preparation made of 11 strains of very commonly used probiotics and the other were given a placebo. Of those who were given probiotics, he said, "We could group the individuals into two distinct groups: one which resisted the colonisation of the probiotics, and one in which the probiotics colonized the gut and modified the composition of the gut microbiome and the genes of the host individual."
Shame on those poop eaters. All for nothing lol.
The Night Defender Eugenia Loli Sweating and farting nervously on the verge of mental meltdown, ELQ reloads each of her precious OSNews pages, making sure all is well. Fifty Internet Explorer windows are open in Windows XP, it's grinding the hard drive to death. ELQ's cable modem and NIC activity LEDs are nearly solid from the raw frenzy of almost constant browser reloading. Eugenia's eyes twitch rapidly from window to window with mercurial speed to make sure that any rogue comments do not escape her attention, always hitting her refresh buttons with pinpoint accuracy. No logical order for checking, purely random and impulse driven by raw Mediterranean temper, stopping for the occasional savage bite from a greasy pork loin still affixed to the bone, Eugenia's eyes never leave the monitor. "N-n-n-n NO! No TIME for Dance Dance Revolution, oh but it's been so long! I cannot allow the BASTARD flooders' comments to be seen. MY DOMAIN IS SACRED!" Hair is frizzled and days unwashed, ass-crack just barely half wiped in a frenzy to return to her monitor, having taken a large shit earlier. No time to flush! Her armpits are over-ridden with pubic hair, her fat flaps reek of B.O. and yeast from days of neglect and hour upon hour of sweating. Relentless sweating. "Cannot to be keeps up this pace! I may be need to go to hospital for exhaustions" she pants in desperation, wiping the sweat from a matted hair lock with her week-old t-shirt offering. The hour of judgment approaches! Comment number 45 in thread 374 is clearly of anti-Greek sentiment! It reads "Eugenia continues to post yet another story that's simply ripped off from other websites. How much longer can this continue? It's my opinion that she has poor editorial skills. I think they should be revoked." "YOU BASTARD FUCK!", Eugenia erupts in raw hatred, simultaneously ripping a 120 decibel-at-1-meter fart into the back of her chair. "Nobody is to be attack my site!" Eugenia blasts away at 10 words per minute in a barely-coherent broken English. She's on a mission. After several hours, the words on the screen are completely shattered and in disarray, they make no sense. Eugenia is impressed with her English progress and submits her lousy retort. Relaxing only for several seconds to savor the rush, she continues her patrol, sleepless into the night. Eugenia claims she has 600 acres and a 4 storey house Yup, a self-employed pissing loser with a family, 600 acres of deeded land, several automobiles and a four-story house. What do you have? 2,000 British pounds to your name, a playstation2, some computers and a husband that picks up the tab for everything? That's what I thought, you fucking olive-picking, highboot fecal smear of a bridge troll. RESPONSE: Well, what a waste of a good fortune. Assuming that it were true, of course. Which is something that most of us won't do, given your gutter-mouth rambling and apparent poor breeding. Taken from OS News posting by Eugenia 03/04/2000 Your post would be a lot more credible if you omitted like every 25th word to simulate your bad English. Actually I didn't even read it at all, isn't that awesome? To Eugenia-- Have you ever taken a step back and looked at your life? Taken a calming deep breath, cleared your head, and assessed the situation? Looked around at what you have made for yourself, what you've done and how it's affected you? If you had, it wouldn't be hard to see that things aren't as rosy as most people would be comfortable with; furthermore, it seems as if you're not comfortable with you or your situation either. It's no large feat to realize that things in your life are falling apart, and have been for quite a while. In fact, you don't really seem to have a life now and all that you own or have is going to go away eventually because it's not yours. Yes, Eugenia, here's the simple, terrible truth: your life is in shambles and it's only getting worse. Let's take a look at the swill and depravity that you live in. Your Slashdot journal entry from Saturday, March 02, 2002 encapsu
I am well aware that there is a symbiosis at work in my digestive tract. But that still doesn't make me feel good about gulping down live cultures of bacteria like that. ICK!
My disgust at the thought of eating probiotics is only dwarfed by the horror I experienced when I learned about non-surgical fecal transplants!
Oh, I am reacting just typing that.
The world is a horrifying place.
Been saying this for years. I get some people have IBS but the reliance on things like yogurt is crazy.
Fun little tip for a stomach ache - saliva. Let it build in your mouth (without water) and swallow in one gulp. Not only does it give your mouth a natural way to break down any bateria / sugar, but helps to calm your gut. Mouthwash is the nuclear option.
So much of how your body functions comes down to diet. It's interesting they do not go into what foods were consumed.
But what does it all mean, Basil?
Was it for the better that "probiotics colonized the gut and modified the composition of the gut microbiome and the genes of the host individual"?
shit transplants for the health crazed. /s
Seriously, is anything really good or really bad for you in moderation?
Don't waste your money on probiotic capsules. If you want to try to increase the amount or variety of bacteria in your guts, there are tons of delicious foods that are chock full of probiotics. Olives, pickles, fermented meats like the Italian delicacy soprasetta (which might be the tastiest thing ever invented by humans). Kimchi is also good, but it will make you smell bad, so if you're single, you might want to go easy on the kimchi.
Also, if you use vinegar on salads, try getting some of that good cider vinegar that still has the "mother" in it. Shake the bottle and use like any other vinegar. And of course, yogurt, kefir, that kind of stuff is delicious too.
I'm not crazy about kombucha. It's a big fad now and there are places here in California that have kombucha on tap, but it's not really to my taste. Some people swear by it. I notice that now when you buy it in the store, they ask for an ID since there's a small amount of alcohol in it.
Also, alcohol is not really good for your gut bacteria, but there are more important things in life than gut bacteria, you know? Just eat a lot of different kinds of food and you'll end up with good gut bacteria without even trying.
You are welcome on my lawn.
Most probiotics are a pretty small range of bacteria, and I don't know if I've ever seen anywhere that confirms these are actually the ones we want on a large scale...especially when some supplements have pretty large doses of these.
From all the reading I've done it seems the best direction will be to focus on prebiotics, aka the foods that the microbiome thrives on, which is typically fibrous vegetable matter. Feed the good ones you've got (rather than trying to implant others), and you'll probably be better off.
... that smoking is bad for my health.
What idiot thinks that if you give pills of a specific biome you will get something BESIDES that specific biome???? Look, if you take probiotic pills, you are replacing your normal biome WITH the biome of the pills.
That was the presumed GOAL of taking the pills. The fact that your biome change is the thing you were trying to do, that's why you take the pills.
If you have a blue car, and then paint it with red paint you are an idiot if you complain that the car is no longer red.
There are lots of good reasons to try and change your microbiome. We are pretty sure that some microbiomes cause ulcers, obesity, and even diabetes, We have suspicious about cancer, autism, autoimmune diseases, and many other things.
We don't know much about microbiomes, we are not sure about a lot of things and it might make zero sense to take a probiotic pill. But it also might make a lot of sense.
These studies don't answer the real question. They have nothing to do with it being beneficial or not, they just show that a change has occurred. They are talking about whether the pills change your biome, (and they do), not about whether it is a good idea to change your biome by taking the pills.
excitingthingstodo.blogspot.com
Why? WHY?
Government funding for impartial research is long gone. Why would anyone take a study like this at face value?
Conclusion: Privately funded research replaces the academic biome with a pathogenic strain.
It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
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The summary (and you really don't expect me to read TFA do you?) does not make clear at all why this would be a bad thing.
The researchers found the microbiomes of those who had taken the probiotics had suffered a "very severe disturbance." "Once the probiotics had colonized the gut, they completely inhibited the return of the indigenous microbiome which was disrupted during antibiotic treatment," said Eran Elinav, an immunologist at the Weizmann Institute of Science in Israel and lead author on the studies.
OK. Is that a bad thing then?
Is the "indigenous" microbiome automatically better than the probiotic? (Maybe it has cool costumes and casinos and stuff)?
I mean, it might be better, but the summary isn't giving us any hint why
Instead of not taking probiotics, how about not taking antibiotics at all.
I think you meant this Soppressata or this Sopressa.
Small correction, since I was actually wondering what you meant (and I've been living in Italy for >30 years...).
"very severe disturbance." "Once the probiotics had colonized the gut, they completely inhibited the return of the indigenous microbiome which was disrupted during antibiotic treatment,"
Isn't that the entire point of taking probiotics? To populate the gut microbiome with whatever you are ingesting? Who in their right mind would have theorized anything else occurring? The entire point is to get those strains of bacteria in the guts. How is that a "very severe disturbance"?
that's how yoghurt is made. Same with cheese. How did you think they were made?
saddly some cheap industrial process are just mixing in cheap acids to accelerate the precipitation.
you also get a firm product at the end just like with naturally occurring lactic acid, but with less waiting for the fermentation to produce those.
but yes, the *real* one relies on fermentation.
"Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
They do mostly nothing with healthy people, who have a digestic system that can cope with it. They experimented with it on sick people and that didn't turn out very well: much more people died in the group that got probiotics than in the placebo group: https://www.marshallprotocol.c...
I thought the whole point of probiotics was to recolonize/alter the gut bacteria, and that those probiotic interventions were beneficial??
Although I must admit to having doubts too. How do live cultures make it through the stomach's acidic environment intact? I thought that Helicobacter pylori (the main cause of stomach ulcers) was one of the few bacteria able to handle the acidity?
"The researchers found the microbiomes of those who had taken the probiotics had suffered a "very severe disturbance."
A pound and a half of Sauerkraut can do that for you.
“Once the probiotics had colonised the gut, they completely inhibited the return of the indigenous microbiome which was disrupted during antibiotic treatment,”
Isn't that the point of taking probotics, to replace you bad gut bacteria. After taking biotics, which like nuke in your gut, good gut bacteria comes back, i wont call that a negative effect. What is this rubbish?
"However, the studies did not look at clinical effects of probiotics and more research remains to be done in this respect."
Hence my point incomplete rubbish until a real conclusion is reached.
Sony guts.
Depends if she has yeast infection tendencies...
Probiotics are good, probiotics are not so good.
Coffee is bad, coffee is good.
Wine is good, wine is bad.
Calories are bad, no carbs are bad.
Nutrition is complicated. Science will continue to find seemingly contradictory conclusions forever.
So what's a person to do? Do what Grandma always said: don't overdo anything. Sure, eat yogurt, but don't live on the stuff. Drink coffee, but don't drink ONLY coffee. Drink wine, but not too much. And so on.
It's not rocket science.