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Large Genetic Study Finds First Genes Connected With ADHD (arstechnica.com)

A paper published in Nature Genetics this week looked at genetic data from more than 50,000 people, finding 12 different regions of DNA that seemed to play a role in increasing ADHD risk. Ars Technica reports: This evidence comes from a genome-wide association study, or GWAS: a close look at how the DNA of people with ADHD differs from those without. Geneticist Ditte Demontis and her colleagues used data from more than 20,000 people with ADHD, comparing them to a control group of 35,000 people without an ADHD diagnosis. They found 304 points where tiny differences in DNA -- like single letter swaps -- were distributed across their two groups in a statistically telling way. If any of those variants were very close together, the researchers counted them as representing the same stretch of DNA, grouping them together into 12 important regions.

There were correlations between the genetic risk for ADHD and a range of other conditions, including depression and anorexia. That ties in with the idea that genetic variation might be important in a way that plays out system-wide. Some of the genes they identified are also known to be involved in other neurological conditions, including speech and learning disabilities, depression, and schizophrenia.

4 of 117 comments (clear)

  1. Re:Makes sense by jblues · · Score: 3, Funny

    Doh, I was going to make the first post, mentioning this, however I got distracted.

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    If it acquires resources on instantiation like a duck, then its a shared_ptr<Duck>
  2. Took long enough! by wolfheart111 · · Score: 4, Funny

    The Researchers kept getting distracted :(

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    [($)]
  3. ADHD, the disease of not wanting to be confined by Jarwulf · · Score: 3, Informative

    in a four wall box all day long doing meaningless tasks for a giant abstract system or learning to do meaningless tasks for a giant abstract system that normal healthy humans naturally want to do.

  4. Re: Please leave these alone by Anonymous Coward · · Score: 3, Informative

    The diagnosis is not really vague. There are specifics.
    If you don't really meet them strongly, you probably don't have it.
    I have a son with it and we knew even when he was a baby that he was different. Turns out he matches the textbook symptoms and it is only with medicine that he can cope with his disability, i.e, participate successfully in society, and he has only a moderate case. None of his other brothers have ADHD.